13978 results about "Cosmetics" patented technology

The invention belongs to the technical field of cosmetics, and discloses anti-aging recombinant collagen as well as a preparation method and application thereof. The amino acid sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.1, and the nucleotide sequence of the anti-aging recombinant collagen is as shown in SEQ ID NO.2. The recombinant collagen CaI1 is constructed and expressed by recombining the effective sequences of the I-type collagen, the III-type collagen and the XVII-type collagen, and the recombinant collagen CaI1 is free of cytotoxicity, free of hidden danger of endotoxin and good in safety. The skin care product added with the recombinant collagen CaI1 can promote skin collagen absorption, inhibit skin aging and improve skin elasticity, and has a good application prospect.

The invention relates to a recombinant A type humanized XVII type collagen as well as construction and application thereof, the protein is the humanized XVII type collagen which is composed of an intracellular region, a transmembrane region and an extracellular region, and the amino acid sequence is as shown in SEQ No. 1. The hair follicle repairing agent has the advantages of hair follicle repairing, hair regeneration, good biological activities of cell proliferation, cell adhesion and the like, and can be widely applied to the fields of medicines, medical instruments, biological materials, tissue engineering, cosmetics and the like. The gene sequence of the recombinant A type XVII collagen is 100% identical to the corresponding part of the gene sequence of the recombinant A type XVII collagen, so that the recombinant A type XVII collagen has good hydrophilicity and high activity, and has application potential in the fields of biomedical materials, beauty cosmetics, skin care products and the like.

The invention discloses a cosmetic composition and a preparation method thereof, and belongs to the technical field of cosmetics. The invention discloses a chamomile essential oil toner which is mainly prepared from the following raw material components in parts by mass: 10 to 20 parts of modified toner, 50 to 60 parts of water, 4 to 6 parts of glycerol, 2 to 4 parts of propylene glycol, 0.8 to 1.2 parts of sodium chloride, 6.5625 to 7.875 parts of chamomile essential oil polymer micelle, 2.1875 to 2.625 parts of adhesive, 10.5 to 11.5 parts of capric triglyceride and 0.8 to 1.2 parts of cetyl polyethylene glycol. Through the synergistic effect of the modified toner and chamomile essential oil polymer micelles in a specific ratio, the dispersion stability of the toner is improved, meanwhile, the slow release effect of active ingredients is enhanced, and the chamomile essential oil toner has the advantages that the makeup holding property, the storage stability and the mildness are improved, meanwhile, the toner dispersity is improved, and the sensitive skin stimulation risk is reduced.

A stick-type cosmetic container comprises: a main body; a rotary body which is rotatably coupled to the main body and which has a rotary screw thread formed thereon; an elevation member, which is coupled to the inner side of the main body and rises, includes a stick cosmetic, and has an elevation screw thread; a remaining-amount withdrawal member which is coupled to the elevation member so as to push the stick cosmetic outward, and which has a screw protrusion; and an elastic member provided between the elevation member and the remaining-amount withdrawal member.

The invention provides a recombinant XVII type collagen and application thereof, and relates to the technical field of protein engineering. The novel recombinant human XVII type collagen is obtained by optimizing and screening collagen structural domain sequences of the human XVII type collagen and then combining the sequences. The recombinant human XVII type collagen is consistent with the corresponding part of the amino acid sequence of the human XVII type collagen, does not generate immunological rejection when being applied to a human body, and can be widely applied to the industries of surgical medical treatment and medical beauty. In addition, the recombinant human XVII type collagen is high in stability, and the problem of protein degradation in the process of expressing recombinant protein by pichia pastoris can be avoided. In addition, the recombinant human XVII type collagen also has the effects of high biological activity, high biological safety, promotion of cell proliferation and differentiation and promotion of hair growth, and can be applied to the field of cosmetics or medicines as a functional component.

The invention relates to a preparation method of a tricholoma matsutake fermentation product with anti-wrinkle and firming effects as well as a product and application of the tricholoma matsutake fermentation product. The preparation method comprises the following steps: mixing a composite plant extract, a carbon source, inorganic salt and water, then sterilizing to obtain a sterilized culture medium, inoculating a composite probiotic agent into the medium, and carrying out fermentation culture to obtain the tricholoma matsutake fermentation product with anti-wrinkle and firming effects. Centrifuging, filtering and sterilizing the culture product to obtain a tricholoma matsutake fermentation product; the bacterial strains in the compound probiotic agent comprise a combination of streptococcus thermophilus, a lactobacillus paracasei YK-L003 bacterial strain and a saccharomyces cerevisiae YK-S001 bacterial strain. According to the invention, specific strains are subjected to compounding and combined fermentation, and the fermentation product filtrate obtained after fermentation treatment of the three strains has an excellent skin conditioning effect, can effectively improve the skin state and resist and weaken wrinkles, and has an excellent effect when being applied to moisturizing and anti-wrinkle cosmetics.

The invention belongs to the technical field of cosmetic production, and discloses an anti-wrinkle composition and a preparation method and application thereof as well as cosmetics, the anti-wrinkle composition comprises a flos magnoliae extract and an emblic leafflower fruit extract, and the mass ratio of the flos magnoliae extract to the emblic leafflower fruit extract is (0.1-8): (0.5-10); through the synergistic effect of flos magnoliae and fructus phyllanthi contained in the composition, the composition not only has good elastinase inhibition ability, but also has excellent antioxidant ability, so that the composition has good elastinase inhibition ability and good free radical scavenging ability, and further achieves good anti-wrinkle performance.

The invention belongs to the technical field of cosmetics, and particularly relates to essence with anti-wrinkle, repairing and skin-brightening effects as well as a preparation method and application of the essence. The essence is prepared from the following components in parts by weight: 10 to 70 parts of herba centellae extract, 0.0015 to 0.04 part of crocus sativus extract, 0.5 to 2.5 parts of spirulina maxima extract, 0.015 to 0.2 part of radix gentianae extract, 0.1 to 1.5 parts of panthenol, 0.25 to 1.5 parts of leuconostoc / radish root fermentation product filtrate, 0.1 to 1.5 parts of carnosine and 0.21 to 5.3 parts of anti-wrinkle components. According to the essence, various effective components such as the centella asiatica extract, the spirulina maxima extract and the radix gentianae extract are matched for use, a unique composite formula is formed, all the components promote one another, the anti-wrinkle, repairing and skin brightening effects of the essence can be remarkably enhanced, and therefore all-around skin care is provided for consumers, and the essence has a good market prospect. The overall quality of the skin can be effectively improved.

The invention relates to the technical field of synthetic biology, in particular to recombinant XVII type collagen as well as a preparation method and application thereof.The amino acid sequence of the recombinant XVII type collagen comprises a sequence shown in any one of SEQ ID NO.1-SEQ ID NO.3. The recombinant XVII type collagen can be highly expressed in an escherichia coli and pichia pastoris system, the expression system is simple, the cost is low, and the recombinant XVII type collagen is suitable for industrial production. The yield is high; the biological activity is good. The protein can be compounded with other proteins to form raw materials of tissue engineering products, cosmetics, health care products or medicines, so that the protein can be widely applied to the fields of medicines, medical instruments, biological materials, tissue engineering, cosmetics and the like.

The invention discloses a preparation method of an anti-aging cosmetic containing exosome, and relates to the technical field of cosmetic preparation, the cosmetic is prepared from the following components in percentage by mass: 1.01%-5.05% of exosome wrapped by liposome, 0.5%-3% of an antioxidant, 1%-3% of a centella asiatica extract, 1%-3% of a rhodiola rosea extract, 10%-15% of a humectant and the balance of a basic matrix; wherein the exosome wrapped by the liposome is a mixture formed by mixing an exosome secreted by adipose-derived mesenchymal stem cells and an exosome secreted by plant cells according to a mass ratio of 1.5: 1.2; the plant is ginseng. According to the skin care product, the antioxidant, the centella asiatica extract and the exosome act together to improve the DPPH clearance rate of the skin care product, the skin brightness is improved, the roughness is reduced, and the excellent anti-aging performance is achieved. The lipid exosome-antioxidant-centella asiatica ternary system disclosed by the invention has a multi-target synergistic effect.

A lotion applicator for applying a lotion or skincare product to hard-to reach portions of the body is disclosed. The lotion applicator includes a handle or elongated rod. The handle includes a jaw-like structure or clamp capable of releasably holding a roll-on lotion or bottle containing lotion, soap, gel, pain relief lotion, personal care product, cleaning agent, cosmetics and the like. The clamp presents a first part and a second part forming a receptacle for holding the roll-on lotion. The length of the handle is adjustable allowing a user of the lotion applicator to reach the entire area of the back of the user and apply the lotion.

The invention relates to a composition with oil control and dandruff removal effects and application, and belongs to the technical field of cosmetics. The invention provides a composition with effects of controlling oil and removing dandruff. The composition is prepared from a soapberry fruit extract, a camellia seed extract, an artemisia annua extract, a fructus forsythiae extract, a fructus chebulae extract and an eclipta prostrata extract. Researches show that the composition composed of the components limited in the specific ratio can synergistically improve the 5alpha reductase inhibitory activity and the malassezia inhibitory activity, and the composition has remarkable oil control, bacteriostasis and dandruff removal effects. Furthermore, after the shampoo prepared from the composition provided by the invention is used in a short time, the scalp grease secretion and dandruff conditions of a subject are obviously improved. Therefore, the composition provided by the invention can efficiently regulate and control scalp micro-ecology and sebum secretion, remarkably reduce dandruff generation and realize the effects of controlling oil and removing dandruff.

The invention discloses a tightening and whitening composition containing EGCG (epigallocatechin gallate) as well as a preparation method and application of the tightening and whitening composition, and relates to the technical field of cosmetics. The invention provides a tightening and whitening composition containing EGCG (epigallocatechin gallate). The tightening and whitening composition is prepared from the following components in parts by weight: 0.1 to 2 parts of an epigallocatechin gallate nano composition, 0.05 to 0.5 part of a nucleic acid tetrahedron and 0.5 to 5 parts of glassine. When the EGCG nano composition, the nucleic acid tetrahedron and the glassine are cooperatively used, the stability of a formula can be improved, meanwhile, the EGCG can be accurately released to an epidermal layer due to the enzyme-responsive degradation characteristic (such as matrix metalloproteinase MMP-2 triggered depolymerization) of the nucleic acid tetrahedron, and the glassine is released after deeply penetrating into a corium layer along with a nucleic acid tetrahedron carrier, so that the EGCG can be accurately released to the epidermal layer. The synergistic effects of the three components on whitening and tightening are better exerted.

The invention relates to the technical field of cosmetics, and discloses an anti-inflammatory soothing cosmetic composition which comprises the following components in percentage by weight: 0.5%-4% of a barrier repairing component, 0.5%-3% of an immunoregulation component, 0.3%-2.5% of a nerve soothing component, 0.3%-3% of an anti-inflammatory plant compound, 1%-10% of a moisturizing soothing enhancer and the balance of auxiliary materials. According to the components, through a five-dimensional synergistic mechanism of barrier repair, immune tolerance, nerve desensitization, anti-inflammatory itching relieving, moisturizing and stability maintaining, anti-inflammatory relieving and barrier repair are remarkably enhanced; ceramide, rare ginsenoside, phytosterol ester and free fatty acid are introduced to synergistically construct a bionic liposome which is closer to the composition of human cuticle lipid, so that the transdermal absorption and stability are enhanced, and the repair efficiency is remarkably improved; the dipotassium glycyrrhizinate, the tamarix chinensis flower extract, the purslane extract, the dinoflaxanthine and the baicalin cooperate to quickly resist inflammation and relieve itching and strengthen barrier repair, so that the composition is suitable for highly sensitive skin.

The invention relates to a whitening and anti-aging composition suitable for sensitive skin and application of the whitening and anti-aging composition, and belongs to the technical field of cosmetics. The composition comprises bakuchiol, hydrolyzed royal jelly protein, a radix pseudostellariae extract and a golden camellia flower extract as active ingredients. The bakuchiol has the effects of resisting aging, resisting oxidation, resisting inflammation and the like; the hydrolyzed royal jelly protein can help to relieve skin discomfort, preserve moisture, enhance the skin barrier function and the like; the golden camellia flower extract has the effects of resisting light aging, whitening skin, fading spots, resisting inflammation and relieving allergy, and the radix pseudostellariae extract has the effects of resisting inflammation, resisting oxidation, resisting aging and the like. According to the composition disclosed by the invention, through reasonable blending of the components, synergistic interaction can be realized, the effects of resisting inflammation, whitening and delaying senescence are remarkably improved, and the composition contains natural components, is mild and non-irritant, is suitable for sensitive skin and can be applied to various cosmetics.

The invention belongs to the technical field of medicines, cosmetics and scalp care, and particularly relates to application of coniferaldehydes and derivatives or salts of the coniferaldehydes to preparation of medicines and cosmetics for promoting hair regeneration and treating chemotherapy-induced alopecia (CIA, CIA) and other types of alopecia, in particular to application of the coniferaldehydes and the derivatives or salts of the coniferaldehydes to preparation of the medicines and the cosmetics. Experimental results show that coniferyl aldehyde can promote hair regeneration of mice, accelerate hair growth of the mice and effectively relieve alopecia symptoms of the mice after chemotherapy, and the effect of coniferyl aldehyde is better than that of minoxidil. According to the application, coniferyl aldehyde or a composition thereof is given to a subject, so that the vigor of hair follicles is remarkably enhanced, the stationary period of the hair follicles is shortened, and the hair loss process is inhibited. The coniferyl aldehyde provided by the invention has the industrial application advantages of reliable biological safety, controllable preparation cost and high raw material accessibility, can be obtained by a plant extraction or chemical synthesis method, is suitable for an external solution, gel or a scalp care preparation, and provides a natural, safe and effective solution for alopecia patients.

The invention belongs to the technical field of cosmetics, and discloses a wrinkle-removing and anti-aging composition containing recombinant collagen as well as a preparation method and application of the wrinkle-removing and anti-aging composition. The composition is prepared from the following components: 20.4 to 35.6 percent of glycerol, 1.1 to 3.5 percent of 1, 2-hexanediol, 8.2 to 15.4 percent of apple fruit cell culture extract, 1.6 to 3.2 percent of inositol, 0.2 to 1.0 percent of elastin, 0.1 to 1.7 percent of hydroxyproline, 0.1 to 1.0 percent of sodium polyglutamate, 0.1 to 1.0 percent of sodium hyaluronate, 0.01 to 0.1 percent of acetyl hexapeptide-8, 0.01 to 0.1 percent of fibronectin, 1.72 to 3.21 percent of soluble collagen and the balance of deionized water. The amino acid sequence of the soluble collagen is as shown in SEQ ID NO. 1. The skin care product prepared by adding the anti-wrinkle and anti-aging composition is good in safety and has the effects of resisting wrinkles, improving skin elasticity and resisting aging.

The invention discloses a fructus psoraleae total flavone extract as well as a preparation method and application thereof in promoting hair growth. According to the preparation method of the fructus psoraleae total flavone extract, the specific eutectic solvent is adopted, the ultrasonic technology is combined for extraction, the content of total flavone in the fructus psoraleae extract can be remarkably increased, and the fructus psoraleae total flavone can be efficiently extracted; and the adopted extraction solvent has the advantages of greenness, environmental protection, efficient process, low cost, high safety and the like, and can solve the problems of the existing extraction process. The malaytea scurfpea fruit total flavone extract obtained by the method has the effect of promoting hair growth and can remarkably promote hair follicle cell proliferation and prolong the hair growth period, the prepared external gel product has the hair growth effect, the preparation method is simple, and external use is convenient. The malaytea scurfpea fruit total flavone extract provided by the invention can be used for developing more cosmetics and medical products for preventing alopecia and promoting hair growth, and a new scheme is provided for green extraction of natural active ingredients and treatment of alopecia.

Refill systems and cosmetic packages having such refill systems are provided herein. In some embodiments, a cosmetic package includes: a base having an inner volume and a drive post disposed proximate a bottom of the base, the drive post extending into the inner volume; a refill cartridge configured to be removably disposed within the inner volume of the base, the refill cartridge including a recess configured to mate with the drive post; and a cap configured to rest on the base and enclose the refill cartridge within the inner volume.

The invention discloses collagen polypeptide firming and anti-wrinkle freeze-dried powder, and relates to the technical field of cosmetics. The invention relates to a biological preservative which is prepared from water, butanediol, a bacillus / soybean fermentation product extract, soluble collagen, acetyl hexapeptide-8, panthenol, 1, 2, 4-trimethyl-1, 3-pentanediol and a proper amount of water. The cosmetic is prepared from 1, 2-hexanediol, tetrahydromethylpyrimidine carboxylic acid, hydroxypropyl tetrahydropyrantriol, tremella polysaccharide, saccharide isomeride, a bifidus yeast fermentation product lysate, sodium hyaluronate, DNA sodium, a radix gentianae extract, mannitol, palmitoyl tripeptide-1, palmitoyl tetrapeptide-7, oligopeptide-1, decapeptide-4, oligopeptide-3, hydrolyzed royal jelly protein, folic acid and disodium hydrogen phosphate. The additive is composed of sodium dihydrogen phosphate, citric acid and sodium citrate. The mask can provide rich nutrients for skin, deeply care the skin, moisturize and relieve the skin, tighten the skin, resist wrinkles and make the skin moisturized, glossy, elastic and tight, and is high in use safety and wide in application prospect.

A cosmetic system disclosed herein includes a container with a large-radius, grippable exterior that houses a smaller, modular cosmetic dispenser that can be removed and replaced to facilitate use of the exterior container. In one aspect, the modular cosmetic dispenser may be a solid cosmetic dispenser for lipstick or the like, with the mechanical components for dispensing the cosmetic contained withing the disposable, modular dispenser. In another aspect, the modular cosmetic dispenser may be a fluid cosmetic dispenser for a nail polish or the like, with a reservoir, threaded top, and applicator brush or the like integrated into the modular dispenser. As a significant advantage, this permits the re-use of a high-quality, ergonomically designed container with disposable modular cosmetics dispensers.

The invention relates to a crystal type mild cleansing cream and a preparation method thereof, and belongs to the technical field of cosmetics. The crystalline mild cleansing cream is prepared from the following components: glycerol, a mixed amino acid surfactant, lauryl hydroxyl sulfobetaine, disodium lauryl sulfosuccinate, a chelating agent, citric acid, a preservative, a skin conditioning component and water, wherein the mixed amino acid surfactant is formed by mixing solid potassium cocoyl glycinate, solid sodium cocoyl glycinate and a sodium cocoyl glycinate aqueous solution; the cleansing cream comprises the following components in percentage by mass: 25%-35% of glycerol, 18%-25% of active ingredients of the mixed amino acid surfactant, 3%-4.5% of lauryl hydroxyl sulfobetaine and 1%-3% of disodium lauryl sulfosuccinate. According to the crystal type mild cleansing cream, no extra thickening agent component is used, the cream body which is good in texture and stable is obtained only through synergistic thickening of the three amino acid surfactants, irritation is small, sensitive skin friendliness is achieved, the preparation technology is simple, and cost is low.

An intelligent mirror device, and techniques for operating the device, are provided. The device may include a mirror with an integrated display component, a user interface, sensors configured to capture real-time data associated with the user's face, processors, and memories storing instructions that, when executed by the processors, cause the processors to: receive an indication of a makeup look selected by the user, analyze the real-time data associated with the user's face in order to generate a three-dimensional map associated with the user's face, identify facial features of the user's face on the three-dimensional map associated with the user's face; and cause the user interface to provide, via the integrated display component, guidance associated with applying cosmetic products to the user's facial features in order to achieve the makeup look selected by the user. The guidance may be at least partially superimposed upon the user's face in the mirror.

The invention provides an anti-wrinkle combined cyclic peptide and application thereof in cosmetics, the anti-wrinkle combined cyclic peptide comprises cyclic pentapeptide-4, cyclic tripeptide-5 and cyclic hexapeptide-9, the combined cyclic peptide has a remarkable synergistic effect in the aspects of promoting expression of collagen genes Collagen I, Collagen III and Collagen IV and inhibiting acetylcholine secretion, the skin elasticity and glossiness are remarkably improved, and the anti-wrinkle combined cyclic peptide has a good anti-wrinkle effect. The generation of wrinkles is inhibited, and good anti-aging and wrinkle-removing effects are achieved.

The invention relates to bionic skin barrier cream with a three-layer phospholipid structure and a preparation method of the bionic skin barrier cream, and belongs to the technical field of cosmetics, the bionic skin barrier cream comprises the following raw materials: lecithin, wax ester, triglyceride, composite ceramide, phytosterol oleate, squalane, an antioxidant, polyol, composite amino acid, pyrrolidone carboxylic acid, urea and arginine. A stabilizing agent, a treating agent and the balance of deionized water. The bionic skin barrier cream prepared by the invention has a three-layer phospholipid structure, and compared with a double-layer phospholipid structure in the market, the firmness and hydrophobicity of the double-layer structure are further improved by the added third-layer structure, so that the prepared bionic skin barrier cream has outstanding waterproof, sweat-resistant and light pollution-resistant effects; in addition, the wax ester, the triglyceride, the phytosterol oleate, the pyrrolidone carboxylic acid and the urea selected in the invention have a synergistic effect, and can generate excellent moisturizing and repairing effects and certain protection effects.

The invention relates to the technical field of cosmetics, in particular to a nanoscale repair composition, a nanoscale repair cosmetic and a preparation method and application of the nanoscale repair composition and the nanoscale repair cosmetic. The invention discloses a nanoscale repairing composition. The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 4 to 6 parts of herba centellae extract, 2 to 4 parts of chamomile extract, 2 to 4 parts of radix ginseng extract, 1 to 3 parts of rhizoma curcumae longae extract, 3 to 5 parts of aloe extract, 1 to 3 parts of oat extract, 1 to 2 parts of liquorice root extract, 0.3 to 0.7 part of green tea extract, 0.5 to 1.5 parts of radix salviae miltiorrhizae extract, 0.5 to 1.5 parts of radix angelicae sinensis extract and 0.5 to 1.5 parts of ganoderma atrum extract. , 0.5 to 1.5 parts of radix astragali seu hedysari extract, 0.3 to 0.7 part of rhizoma polygoni cuspidati extract, and 0.3 to 0.7 part of onion extract. The nanoscale repairing composition and the nanoscale repairing cosmetic disclosed by the invention can improve the moisture content of skin, reduce moisture loss and redness of the skin, accelerate healing of injured skin, effectively relieve inflammatory response and promote collagen regeneration of the skin.

The invention belongs to the technical field of analysis and detection, and discloses a method for detecting perfluorinated and polyfluoroalkyl substances in cosmetics, which comprises the following steps: (1) mixing a perfluorinated and polyfluoroalkyl substance standard solution and an isotope internal standard solution to obtain a mixed standard solution; detecting the mixed standard solution by adopting a liquid chromatograph-mass spectrometer, drawing a standard curve, and calculating to obtain a linear equation; (2) mixing a cosmetic sample with the isotope internal standard solution, adding an extracting solution, extracting, and filtering to obtain a mixed solution to be detected; detecting the mixed to-be-detected solution by adopting the liquid chromatograph-mass spectrometer to obtain a detection result, and substituting the detection result into the linear equation to obtain the content of the perfluoro and polyfluoroalkyl substances in the mixed to-be-detected solution, the perfluoro and polyfluoroalkyl substances comprise perfluorocarboxylic acid, perfluorosulfonic acid, a fluorine polymer, perfluoroalkyl ether sulfonic acid, saturated fluorine telomere acid and perfluoroether carboxylic acid.