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50results about How to "Great potential" patented technology

Two-stage potential diffusion model underwater image enhancement method based on frequency domain

The invention discloses a two-stage potential diffusion model underwater image enhancement method based on a frequency domain. The method comprises the following steps: inputting a degraded image and ambient light estimated according to the degraded image into a lightweight underwater image enhancement model to obtain a preliminary recovery image; inputting the preliminary recovery image into a high and low frequency feature pyramid encoder to obtain a potential spatial feature map set and an intermediate feature map set, and inputting the potential spatial feature map set and the intermediate feature map set into a high and low frequency prior extraction module to obtain high and low frequency images and high and low frequency image prior; inputting the low-frequency guidance priori and the potential spatial feature map set of the low-frequency image into a low-frequency guidance condition module to generate a priori guidance condition, and sending the priori guidance condition into a potential diffusion model to obtain a reconstructed potential spatial feature map set; and inputting the reconstructed potential spatial feature map set, the intermediate feature map set and the high and low frequency images into a high and low frequency feature pyramid decoder in prior to obtain an enhanced image. And improving the performance of the potential diffusion model and recovering a high-quality underwater image by using high and low frequency information priori knowledge of the underwater image.
Owner:NINGBO UNIV

Mechanical arm model prediction interaction control method based on hysteresis force model

The invention relates to the technical field of robots, in particular to a mechanical arm model prediction interaction control method based on a hysteresis force model, which comprises the following steps of: abstracting a hysteresis nonlinear phenomenon into a linear combination of a plurality of basic play operators by adopting end force modeling based on a PI (Proportional Integral) model, jointly superposing to form a description of the overall nonlinear behavior; the inverse model of the PI model is constructed in an analysis mode, the inverse model is also a PI model, the parameter of the inverse model is a function of the parameter of the original PI model, and the hysteresis characteristic of the inverse model can be determined by the relation, so that the hysteresis effect of the original PI model is effectively counteracted; and finally, a least square method is adopted as a parameter identification method, model parameters of the hysteresis characteristics of the system are accurately described, and more accurate output is obtained. According to the model prediction interaction control method, the adverse effect of the hysteresis effect on the performance of the control system is remarkably reduced, and greater potential and possibility are provided for application of the robot in the real world.
Owner:GUANGDONG UNIV OF TECH

Metal organic framework sodium ion battery positive electrode material Mn-PTO, and preparation method and application thereof

ActiveCN119570059AReduce migration resistanceFacilitate de-intercalationSecondary cellsPositive electrodesCarboxyl radicalElectrical battery
The invention provides a metal organic framework sodium ion battery positive electrode material Mn-PTO, a preparation method and application, and belongs to the technical field of battery development. According to the material, an organic ligand pyrene tetraketone with conjugate extension is selected, 2, 7-dicarboxyl-4, 5, 9, 10-pyrene tetraketone PTO-(COOH) 2 is synthesized through a series of reactions, and the material has four energy storage sites and can provide high specific capacity. The high reversible specific capacity of 160.1 mAh g < 1 > can be achieved under the current condition of 0.1 A g < 1 >; even under the current condition of 5A g < 1 >, the reversible specific capacity of 118.1 mAh g < 1 > can be realized after 7000 cycles. And stable circulation can be carried out for 10000 times under the high current of 10A g < 1 >. Therefore, the material has huge potential in the aspect of being used as a sodium-ion battery positive electrode.
Owner:NANJING TECH UNIV

Two-dimensional lead-based perovskite PVDF piezoelectric-photoelectric composite film and preparation method and application thereof

According to the two-dimensional lead-based perovskite PVDF piezoelectric-photoelectric composite film as well as the preparation method and the application thereof, (2-FBA) 2PbCl4 and PVDF are compounded, so that the content of a beta phase with a high piezoelectric constant in PVDF is effectively increased, the voltage output performance of a composite piezoelectric sensor is enhanced, meanwhile, the two-dimensional lead-based perovskite PVDF piezoelectric-photoelectric composite film has good performance in the photoelectric aspect, and the two-dimensional lead-based perovskite PVDF piezoelectric-photoelectric composite film has good application prospects. And a reliable scheme is provided for a piezoelectric-photoelectric self-powered device.
Owner:HUBEI UNIV +1

Preparation method, product and application of dual-emission fluorescence sensor

The invention relates to the technical field of sensor preparation and antibiotic detection, in particular to a preparation method of a dual-emission fluorescence sensor, a product and application of the dual-emission fluorescence sensor. The preparation method of the dual-emission fluorescence sensor comprises the following steps: dissolving 1, 3, 5-benzene tricarboxylic acid and melamine in an organic solvent to prepare a suspension; the suspension liquid is subjected to a first heating reaction and then mixed with zinc salt to be subjected to a second heating reaction, and Zn-MBTC is obtained; the preparation method comprises the following steps: dissolving Zn-MBTC and Ru (bpy) 3 < 2 + > in water, carrying out ultrasonic treatment and oscillation, and then washing, centrifuging and drying to obtain the dual-emission fluorescence sensor. The dual-emission fluorescence sensor prepared by the method has the advantages of high sensitivity and high detection speed when being used for detecting four tetracycline antibiotics, namely doxycycline, tetracycline, oxytetracycline and gold tetracycline, and the detection limit is as low as 0.013 mu mol / L.
Owner:HEBEI UNIVERSITY

Silver-coated calcium carbonate multilayer core-shell structure composite powder and preparation method thereof

The invention discloses silver-coated calcium carbonate multi-layer core-shell structure composite powder and a preparation method thereof.The preparation method comprises the steps that firstly, the surface of inner core calcium carbonate is coated with a layer of SiO2 through a sol-gel method, a CaCO3 at-SiO2 core-shell structure is formed, then Ag is loaded on CaCO3 at-SiO2 through a reduction method, and the core-shell structure composite powder with CaCO3 at-SiO2 at-Ag double-layer shell layers is formed. According to the method, silicon dioxide is ingeniously used as a middle layer, calcium carbonate and silver can be well combined together in the presence of silicon dioxide, and the problem that calcium carbonate cannot be coated with silver is solved. The method provided by the invention provides a new method for preparing a calcium carbonate core-shell structure, and also provides a new research thought for inorganic coating.
Owner:GUANGXI UNIV FOR NATITIES +1

Tough, flame-retardant and hydrophobic reactive polyurethane based on polyhydroxy ammonium polyphosphate as well as preparation method and application of tough, flame-retardant and hydrophobic reactive polyurethane

The invention discloses tough, flame-retardant and hydrophobic reactive polyurethane (RPU) based on polyhydroxy ammonium polyphosphate as well as a preparation method and application thereof, and belongs to the crossing field of flame-retardant materials and multifunctional polymers. The specific preparation process is as follows: diglycolamine is grafted to the surface of ammonium polyphosphate through a one-pot ion exchange reaction, and hydroxylated ammonium polyphosphate (aAPP) is prepared. The preparation method comprises the following steps: preparing an aAPP-NCO double-end-capped prepolymer, then carrying out an addition polymerization reaction on the aAPP and the NCO double-end-capped prepolymer under a medium-free condition to prepare flame-retardant RPU (aAPPx-RPU), further introducing polydimethylsiloxane (PDMS) into an RPU main chain, and preparing the tough, flame-retardant and hydrophobic RPU by utilizing the synergistic effect of phosphorus (P), nitrogen (N) and silicon (Si). The preparation method of the tough, flame-retardant and hydrophobic RPU is green and efficient, and can be applied to the fields of fireproof flame-retardant materials, building materials, electronic materials and the like which need to improve safety and durability.
Owner:ZHEJIANG SCI-TECH UNIV +1

Lipid nanoparticles and engineered immune cells

The application belongs to the technical field of biological medicine, and particularly relates to a kind of lipid nanoparticles and engineered immune cells. The application first provides an engineered immune cell, the engineered immune cell includes immune cell, lipid nanoparticle and exogenous drug;The exogenous drug is loaded in the lipid nanoparticle;When the immune cell is contacted with the lipid nanoparticle, the immune cell and the lipid nanoparticle endocytosis occur to obtain the engineered immune cell. In another aspect, the application also provides a kind of lipid nanoparticles that can improve the encapsulation efficiency of mRNA and the delivery efficiency of immune cells.
Owner:BLOOD TRASFUSION INST CHINESE ACAD OF MEDICAL SCI

A quaternary solid waste-based soil stabilizer for base layer, and a preparation method and application thereof

The application discloses a quaternary solid waste-based soil stabilizer (GSCP) for a base layer, which is composed of slag (GGBFS), steel slag (SSA), calcium carbide slag (CS) and phosphogypsum (PG) and has a weight ratio of GGBFS:SSA:CS:PG=56:24:12:8. The stabilizer forms C-S-H colloid and ettringite (AFt) through alkaline activation and sulfate activation, does not need to add cement or chemical activator, is used for stabilizing silty clay and steel slag mixed soil, and significantly improves the unconfined compressive strength, splitting tensile strength, water stability and freeze-thaw resistance. Compared with a traditional cement-based stabilizer, the application reduces carbon emission by 82% and cost by 31.25%, provides a low-carbon and economical solution for road engineering, and is suitable for the base layer and the subbase layer of a secondary road or above.
Owner:HUNAN UNIV

Method of reprogramming mueller glial cells to induce cell proliferation and neuronal regeneration

PendingCN122706618APromote neurogenesisgreat potential
The application discloses a method for reprogramming Müller glial cells (MG) to induce cell proliferation and neuron regeneration, and belongs to the technical field of biological medicine. The application constructs an FGF2 / Ascl1 / RA combined reprogramming system. The system induces MG to re-enter the cell cycle under the condition of no neurotoxic injury through FGF2 combined with AAV-Ascl1, and promotes the multi-round proliferation of adult and middle-aged and old MG by using FGF2 / MAPK / PI3K-Akt signals, and further combines with RA to induce MG to maintain a regeneration state for a long time and promote neurogenesis. The reprogramming system established by the application successfully solves a plurality of core technical problems in the field of mammalian retina regeneration. This breakthrough not only provides a brand-new strategy for the regenerative medicine intervention of retina degenerative diseases, but also shows great potential and value of the application from basic research to clinical transformation application, so that the application has a good application prospect.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

A conjugated polymer and a preparation method and application thereof

ActiveCN119119428Bchange colorGood planarityTenebresent compositionsNon-linear opticsBenzeneChlorobenzene
The application discloses a conjugated polymer of chlorobenzene, o-dichlorobenzene or m-dichlorobenzene and EDOT as well as a preparation method and application thereof, and belongs to the field of polymer electrochromic materials. By introducing chlorine atoms as intermediates in different active sites of benzene and EDOT as a strong electron-donating group, the obtained conjugated polymer has the characteristics of a wider redox peak, good optical contrast, fast response time, high coloring efficiency, good stability and the like.
Owner:WUYI UNIV

Hydrogen production system

The application relates to a hydrogen production system. The hydrogen production system comprises an electrolysis cell module and a steam heat pump module. The steam heat pump module comprises a heat pump assembly, a water storage tank and a flash tank. The heat pump assembly comprises a condenser. An outlet of the water storage tank is connected to a cold side inlet of the condenser. A cold side outlet of the condenser is connected to an inlet of the flash tank. An outlet of the flash tank is connected to an inlet of a fuel gas preheater. The steam heat pump module of the application only needs a small amount of electric energy to generate a large amount of water vapor. In the case of the same water vapor yield, the power consumption of the steam heat pump module is only about half of the power consumption of the water vapor generator, achieving a more energy-saving effect. In the case of the same power, the water vapor yield of the steam heat pump module is much larger than the water vapor yield of the steam generator, so that the hydrogen production system of the application can meet the demand of a high-power hydrogen production system.
Owner:SUNGROW ICARBON TECH CO LTD

Whole-vehicle heat pump integrated system of pure electric vehicle

The invention relates to the technical field of automobile air conditioner heating, in particular to a whole-vehicle heat pump integrated system of a pure electric automobile. Comprising a first water pump, a second water pump, a refrigerating device, a first electronic expansion valve, a second electronic expansion valve, a third electronic expansion valve, a first electromagnetic valve, a second electromagnetic valve, a third electromagnetic valve, a fourth electromagnetic valve, an indoor evaporator, an indoor condenser, a radiator, a fan, a compressor, a warm air water tank, an air blower, a three-way valve, a four-way valve, a gas-liquid separator and a water cooling condenser. For the heat dissipation function of the original outdoor condenser, through the heat dissipation path of combining the water-cooled condenser and the radiator with the fan and the improved internal heat dissipation structure, after the PTC and the outdoor condenser are omitted in the system, the structure and pipeline line arrangement is simplified, the fault probability is reduced, the cost is reduced, and the installation and maintenance cost is also relatively reduced; the energy efficiency improvement potential is large, and energy loss links such as PTC working heat loss and outdoor condenser heat dissipation electric energy consumption are reduced.
Owner:LIUZHOU RAILWAY VOCATIONAL TECHN COLLEGE +2

A Micro-Platform for Rapid Electrolysis and High-Sensitivity Electrochemical Nucleic Acid Detection of Cryptococcus and Its Application

This invention belongs to the field of fungal detection technology, specifically relating to a micro-platform for rapid electrolysis and highly sensitive electrochemical nucleic acid detection of Cryptococcus neoformans and its application. The micro-platform includes an integrated microfluidic chip, an external power supply, a sample introduction system, and / or an imaging system. The integrated microfluidic chip includes an electrolysis region, an electrochemical detection region, and an electrode array region. The electrolysis region includes multiple vertically arranged counter electrodes arranged in pairs, and multiple horizontally arranged hollow channels in a serpentine pattern, bonded to the electrode pairs above them. The connection point between every two electroporated channels is the electroporation lysis point. The electrochemical detection region consists of a working electrode, a reference electrode, and a counter electrode. The working electrode is modified with rGO / AuNPs nanomaterials and molecular probes.
Owner:BEIHANG UNIV +1

Doped nickel oxide-based material, preparation method and application thereof

The invention discloses a doped nickel oxide-based material, a preparation method and application thereof, and a synthetic method of the doped nickel oxide-based material, and the synthetic method comprises the following steps: adding a nickel salt and an iron salt into an ethanol and oleylamine solution, fully stirring, transferring the solution into a reaction kettle for heating reaction, then carrying out centrifugal analysis and washing, and then calcining to obtain the doped nickel oxide-based material. And heating the obtained powder and thiourea in a tubular furnace to finally obtain the doped nickel oxide-based material. The synthesis method is mild in reaction condition and easy to operate, the electron and structural properties of nickel oxide are changed through doped metal iron and non-metal sulfur atoms, the conductivity of the system is improved, then the doped nickel oxide-based material can efficiently electrolyze water under the alkaline condition, and the method can be applied to an anode material of alkaline electrolyzed water.
Owner:YANGTZE DELTA REGION INST OF UNIV OF ELECTRONICS SCI & TECH OF CHINE (HUZHOU)

Bacillus firmus BCK018 and application thereof

The invention discloses a bacillus firmus BCK018 strain and an application of the bacillus firmus BCK018 strain. The bacillus firmus BCK018 is preserved in the China General Microbiological Culture Collection Center on July 18, 2024, and the preservation number of the bacillus firmus BCK018 is CGMCC No. 31342. The bacillus firmus BCK018 has the advantages that the fatality rate of the bacillus firmus BCK018 on meloidogyne incognita J2 reaches 86.3%, the growth inhibition rate of fusarium oxysporum is 74.4%, the inhibition rate of the bacillus firmus BCK018 on ralstonia solanacearum is 88.1%, and the microbial agent prepared from the bacillus firmus BCK018 can be used for preventing and treating meloidogyne and soil-borne diseases of various crops and has the advantages of being efficient, safe, environmentally friendly and the like.
Owner:MICROBIOLOGY INST OF SHAANXI

The invention relates to a preparation method of 3, 5-dihydroxy-4apos; -pentylbiphenyl-betaine eutectic as well as preparation method and application thereof

The invention provides a 3, 5-dihydroxy-4 '-pentylbiphenyl-betaine eutectic as well as a preparation method and application thereof, and belongs to the technical field of pesticide preparation. The invention provides a 3, 5-dihydroxy-4 '-pentylbiphenyl-betaine eutectic which is formed by combining 3, 5-dihydroxy-4'-pentylbiphenyl and betaine through an intermolecular hydrogen bond, and a preparation method of the 3, 5-dihydroxy-4 '-pentylbiphenyl-betaine eutectic. According to the 3, 5-dihydroxyl-4 '-pentylbiphenyl-betaine eutectic and the preparation method thereof, the eutectic is formed by BP and BET, the solubility and the dissolution rate of BP are improved, the application amount of pesticide molecules is reduced, and the 3, 5-dihydroxyl-4'-pentylbiphenyl-betaine eutectic is applied to various plant pathogenic fungi. Results of the embodiment show that the co-crystals formed by BP and BET are combined through hydrogen bonds in a molar ratio of 1: 1, the dissolution effect of the co-crystals is superior to that of the medicine, and the dissolution effect is not affected by the pH environment. Compared with drugs with the same concentration and the drug eutecticum, the drug eutecticum shows the antibacterial activity advantage superior to that of original drug molecules.
Owner:INSTITUTE OF CHINESE MATERIA MEDICA CHINA ACADEMY OF CHINESE MEDICAL SCIENCES

Gene detection system for promoting andrographolide synthesis based on biosensor

The invention relates to the technical field of gene engineering detection, and particularly discloses a gene detection system for promoting andrographolide synthesis based on a biosensor, a key gene ApDof29 for regulating and controlling andrographolide synthesis is determined through whole genome analysis, gene expression profile research and co-expression network analysis, the core regulation and control effect of ApDof29 is verified, and the gene detection system for promoting andrographolide synthesis based on the biosensor is used for promoting andrographolide synthesis. The invention also develops a real-time dynamic monitoring system, and realizes non-invasive monitoring of andrographolide content accumulation, biosynthesis rate and metabolic intermediate concentration change by utilizing the fusion of a specific response element and a reporter gene. Through comprehensive calculation processing of an accumulation abnormal coefficient, a synthesis rate abnormal coefficient and a concentration change abnormal coefficient, the regulation and control effect of ApDof29 is dynamically evaluated, and a scientific basis is provided for subsequent gene modification.
Owner:江西省 中国科学院庐山植物园

Preparation and use of gramicidin and its antibacterial hydrogel formulations

The application provides a preparation of gramicidin and an antibacterial hydrogel preparation of the gramicidin, and discloses medical uses of the gramicidin, and provides a recombinant gramicidin, heterologous expression of the gramicidin is realized by constructing a Pichia pastoris recombinant strain, and the antibacterial activity of the gramicidin is retained, and the method has the advantages of simplicity and rapidness. Meanwhile, the hydrogel preparation of the gramicidin provided by the application shows good potential for treating wound infection of a diabetic mouse, and has the performance of rapid adhesion and hemostasis, lays a foundation for development of a new antibacterial drug, and provides a new direction for treatment of chronic inflammatory wounds and open bleeding.
Owner:JILIN UNIVERSITY

A solid electrolyte with a doped modified layer, a preparation method thereof, and solid-state battery application

A solid electrolyte with a doped modified layer and its preparation method and solid-state battery application, which relates to the field of new energy materials. It includes: a base material and a doped modified layer; the general formula of the base material is Li 7‑M PS 6‑M X M , X=Cl, Br, I, 1≤M≤1.6; the doping modification layer contains at least one element of Al, Mg, Fe, Zn, Sn, Ag, Cu, Se, Bi, Si, Mo; the interplanar spacing of the solid electrolyte (111) crystal plane is d(111), 0.54nm
Owner:BEIJING UNIV OF TECH

Pantoea agglomerans e-102, microbial inoculant and application thereof

The application provides a pantoea vagans E-102, a microbial inoculant and application thereof, and belongs to the technical field of microorganisms. Pantoea vagans The Latin name of the pantoea vagans E-102 is CCTCC NO:M 20261185. The pantoea vagans E-102 has excellent antagonistic activity on various pathogenic fungi. The plate confrontation test shows that the strain can significantly inhibit the growth of verticillium albo-atrum, fusarium graminearum, pyricularia oryzae, botrytis cinerea and sclerotinia sclerotiorum; the volatile substances also have strong bacteriostatic effect on pathogenic fungal hyphae. The indoor potting test proves that the strain has significant prevention effect on cotton verticillium wilt; the 90-day outdoor potting test further proves that the strain has stable and long-acting prevention and treatment capacity on cotton verticillium wilt. In conclusion, the pantoea vagans E-102 has good application prospect in the field of biological control of fungal diseases of cotton and other crops.
Owner:HUAZHONG AGRI UNIV

Baslaromyces pinophilus and application thereof

PendingCN121780338Aincrease plant heightIncreased fresh weightBiocideAgriculture tools and machines
The invention discloses talaromyces pinophilus and application thereof. Belongs to the technical field of biological control. According to the invention, a strain HY25 capable of efficiently antagonizing seven kinds of tobacco fusarium is separated from rhizosphere of a diseased plant by a tissue isolation method and a plate confrontation method. The talaromyces pinophilus is identified as talaromyces pinophilus through morphological and molecular biological tree establishment. A further research shows that the strain HY25 has various growth-promoting and disease-preventing capacities of dissolving potassium, dissolving phosphorus, fixing nitrogen and the like. Pot experiment results show that the control effect of fermentation liquor of the strain HY25 on tobacco fusarium root rot is 75%, and the strain HY25 has a remarkable growth promoting effect on indexes such as plant height, root length, fresh weight and leaf surface area of tobacco. In conclusion, the strain HY25 has good biological prevention and control potential on the tobacco fusarium root rot, has a growth promoting effect, and enriches biocontrol strain resources of the tobacco fusarium root rot.
Owner:CHINA NATIONAL TOBACCO CORPORATION HUNAN PROVINCIAL CORPORATION +1

Traditional Chinese medicine composition for treating insomnia

The invention provides a traditional Chinese medicine composition for treating insomnia. The invention further provides a traditional Chinese medicine extract. The invention further provides a traditional Chinese medicine preparation. The invention further provides traditional Chinese medicine jelly and a preparation method thereof. The invention further provides application of the traditional Chinese medicine composition, the traditional Chinese medicine extract, the traditional Chinese medicine preparation or the traditional Chinese medicine jelly in preparation of medicines for treating insomnia. The traditional Chinese medicine composition for treating insomnia provided by the invention is suitable for dysphoria and insomnia caused by deficiency of liver blood, yin deficiency and internal heat, and has a remarkable curative effect on patients with dysphoria and insomnia, palpitation and dreaminess, body deficiency and hidrosis, body fluid impairment and thirst.
Owner:SHANGHAI SEVENTH PEOPLES HOSPITAL

In-situ vacuum preparation system and preparation method of memristor

The application discloses an in-situ vacuum preparation system and a preparation method of a memristor, and belongs to the technical field of electronic device manufacturing. The in-situ vacuum preparation system comprises a glove box, and a vacuum collecting and connecting pipeline is connected to one side of the glove box; the vacuum collecting and connecting pipeline can be used for carrying out the following processes respectively: insulating material thermal evaporation, metal material thermal evaporation, reactive ion etching, ion beam etching, electron beam evaporation and magnetron sputtering; the insulating material evaporation and the electron beam evaporation both adopt an electron beam evaporation device; the metal material thermal evaporation and the magnetron sputtering both adopt a magnetron sputtering device; the reactive ion etching adopts a reactive ion etching device; and the ion beam etching adopts an ion beam etching device. Material deposition and electrode manufacturing in the preparation process of the memristor are carried out in the in-situ vacuum preparation system, material pollution and interface defects are avoided, the performance of the memristor is significantly improved, and the preparation process is simplified.
Owner:ANHUI UNIV

Chaetomium aureum FF21 for promoting growth of blueberries and application of chaetomium aureum FF21

ActiveCN119614380ANo negative impact on growthIncrease soluble sugar contentBiocidePlant growth regulatorsBiotechnologyMicroorganism
The invention discloses chaetomium aureum FF21 for promoting blueberry growth and application of the chaetomium aureum FF21. The chaetomium aureum FF21 has a taxonomic name of Arcopilus aureum, is preserved in the China General Microbiological Culture Collection Center on September 19, 2024, and has a preservation number of CGMCC (China General Microbiological Culture Collection Center) No.41521. The chaetomium aureum FF21 has a preservation number of CGMCC No.41521. The chaetomium aureum FF21 has the functions of increasing the content of soluble sugar, SOD enzyme, PPO enzyme and total phosphorus in blueberry plants so as to achieve the effect of promoting the growth of blueberry seedlings, and has great potential of being developed into a microbial agent.
Owner:GUIZHOU UNIV

Post-quantum digital signature key generation method based on AVX2 acceleration and matrix multiplication optimization

The invention discloses a post-quantum digital signature key generation method based on AVX2 acceleration and matrix multiplication optimization, which comprises the following contents: on the basis of original coding, parallel optimization of signature compression and decompression processes is realized by using an AVX2 instruction set, the coding and decoding efficiency is remarkably improved, and the method is particularly suitable for a large-scale data processing scene. A matrix multiplication optimization method for an algorithm is provided, and recursion operation is avoided by only performing matrix partitioning once. And in combination with a register optimization technology, the memory access is effectively reduced while the calculation accuracy is ensured, and the calculation efficiency in the signature generation process is remarkably improved. A register optimization strategy is introduced in matrix multiplication and addition operation, and a calculation result is stored in a register as much as possible by reducing memory access operation, so that the number of times of writing back to a memory is reduced, the execution efficiency of matrix operation is further improved, and the method has important significance on efficient implementation of a post-quantum digital signature scheme.
Owner:NANJING UNIV OF AERONAUTICS & ASTRONAUTICS

Preparation method and application of LRG1-targeted enzyme-responsive nano-drug

PendingCN119656173Aincreased mortalityImprove anti-tumor efficacyOrganic active ingredientsDigestive systemDrug conjugationDrug target
The invention provides an enzyme-responsive nano-drug targeting LRG1 protein, and belongs to the technical field of biological medicines, and the nano-drug is formed by co-assembling an amphiphilic drug conjugate and a carried hydrophobic drug. Wherein the drug conjugate comprises a hydrophilic end of ET peptide targeting LRG1 and a hydrophobic end of the cytotoxic chemotherapeutic drug, the hydrophilic end is covalently linked with the hydrophobic segment through an enzyme-responsive linker, and the hydrophobic drug is entrapped in the amphiphilic drug conjugate. The preparation method comprises the following steps: dissolving the amphipathic drug conjugate and the hydrophobic drug in an organic phase, uniformly mixing the amphipathic drug conjugate and the hydrophobic drug under an ultrasonic condition, dispersing the mixture into a water phase, and standing at room temperature to obtain the targeted response type nano-drug which can prolong the in-vivo circulation time of the drug, realize efficient targeting of a colorectal tumor part, remarkably inhibit the growth of the colorectal tumor of a mouse, and has a good application prospect. DNA damage of tumor cells is promoted, tumor cell apoptosis is induced, and an effective and accurate novel method is provided for enhancing the colorectal cancer treatment effect.
Owner:ZHENGZHOU UNIV

An iron-containing diatom shell material, its preparation method, its application, and a method for preparing a tannic acid-diatom shell composite material containing this material.

This invention discloses an iron-containing diatomaceous earth shell material, its preparation method, applications, and a method for preparing a tannic acid-diatomaceous earth shell composite material containing this material. The iron-containing diatomaceous earth shell material contains at least 0.4% iron by weight and at least 88% silicon, retaining the highly ordered nanoscale porous structure of natural diatomaceous earth shells. The preparation method involves culturing diatoms in G11 medium supplemented with sodium silicate nonahydrate and ferrous sulfate heptahydrate, followed by extraction via hydrogen peroxide oxidation, acid washing, and high-temperature calcination. This invention further utilizes the reaction of this iron-containing diatomaceous earth shell with tannic acid in a buffer system at pH 7.0-8.0, achieving efficient loading of tannic acid through the coordination of iron ions with tannic acid and physical adsorption. This invention features a simple process, low cost, and environmental friendliness. The prepared composite material significantly improves the chemical stability and bioavailability of tannic acid, showing broad application prospects in biomaterials fields such as drug delivery, antibacterial applications, and tissue engineering.
Owner:YANTAI INST OF COASTAL ZONE RES CHINESE ACAD OF SCI

Zif-8 / algal powder-based composite aerogel and preparation method and application thereof

The ZIF-8 / algae powder-based composite aerogel, preparation method and application thereof relate to the field of environmental engineering and material science technology. A novel chitosan / ZIF-8 / algae powder (ZIF-8 / CP / CS) composite adsorbent is synthesized for efficient adsorption of uranium ions in seawater. The results show that the adsorbent has good adsorption performance for uranium in the pH range of 4.0-8.0, and the adsorption rate is all above 89%. Mechanism analysis shows that the hydroxyl, amino, phosphoric acid groups on the surface of ZIF-8 / CP / CS and the C=N bond in ZIF-8 play a key role in the adsorption of uranium, and the quaternary phosphonium salt improves the competitiveness of the adsorbent for uranium. The competitive adsorption experiment shows that compared with the original ZIF-8 and ZIF-8 / C / CS without immobilized ionic liquid, the uranium vanadium ratio of ZIF-8 / CP / CS is increased by 20 times and 6 times respectively. The real uranium tailing pond wastewater is treated by adsorption, and the uranium content of the wastewater is reduced to 40 μg / L, so the adsorbent has good potential for extracting uranium from seawater and good application prospect for recovering uranium from uranium tailing wastewater.
Owner:HENAN UNIV OF URBAN CONSTR