64 results about "Pediococcus sp." patented technology

This invention belongs to the field of food fermentation technology, and specifically relates to a compound probiotic agent and its application in the preparation of fermented soy milk. This invention provides a compound probiotic agent composed of *Lactobacillus fermentum* NCPS LF01, *Pediococcus pentosaceus* NCPS PPE01, and *Lactobacillus acidophilus* NCPS LA01 in a volume ratio of 1-2:1:1, and applies this compound probiotic agent to the preparation of soy products, especially fermented soy milk. The beneficial effects of this invention are that fermented soy milk prepared using this compound probiotic agent has a rich flavor, and the total flavonoid and total phenolic content, as well as the in vitro DPPH free radical scavenging rate, are significantly superior to those of ordinary commercially available strains or other strains. In summary, this compound probiotic agent can effectively improve the retention level of active ingredients and antioxidant capacity of fermented soy milk, and has outstanding application value.

The invention discloses pediococcus acidilactici and application thereof in preparation of a medicine for preventing or treating diarrhea of yak calves, and belongs to the technical field of microorganisms. The pediococcus acidilactici is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M20252012, and the preservation date is September 12, 2025. The strain has remarkable bacteriostatic activity on yak-derived multi-drug-resistant escherichia coli (the accession number of NCBI is PP859186). After the probiotic preparation is orally taken, the yak calf diarrhea induced by escherichia coli can be effectively relieved, the diarrhea rate and the inflammatory factor level are remarkably reduced, the oxidation resistance is improved, the flora structures of intestinal bacteria and fungi are adjusted, and the micro-ecological balance is restored. The invention provides a safe, green and efficient alternative antibody product which is suitable for the plateau yak breeding industry.

This invention discloses a multifunctional Pediococcus pentosaccharide strain and its applications. Pediococcus pentosaceus The strain, named *Pediococcus pentosaceus* A07, has the accession number CCTCC NO: M 2025777 and is deposited at the China Center for Type Culture Collection (CCTCC), located at Wuhan University, No. 299 Bayi Road, Wuchang District, Wuhan City, Hubei Province. This strain is capable of degrading nitrite. Using *Pediococcus pentosaceus* A07 to reduce nitrite content can produce high-quality pickles with good flavor and texture, low nitrite content, and high viable cell count. The *Pediococcus pentosaceus* A07 provided by this invention also possesses cholesterol-lowering, zinc protoporphyrin-forming, antibacterial, and antioxidant capabilities, and produces a high biofilm.

The invention relates to the technical field of microbial food fermentation, and particularly discloses pediococcus acidilactici RM1, a separation method and application, and the pediococcus acidilactici RM1 is characterized in that the preservation number of the pediococcus acidilactici RM1 is GDMCC NO.66765; the preservation unit of the pediococcus acidilactici RM1 is Guangdong Microbial Culture Collection Center; the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1, and the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1. The preservation time of the pediococcus acidilactici RM1 is July 28, 2025. The method has the characteristics of bright red color, difficulty in deterioration during storage and ideal quality and flavor.

This invention discloses a functional feed for sows to combat stress and its preparation method. The functional feed for sows to combat stress comprises the following components by weight: 700-850 parts basal feed, 0.5-3 parts probiotics, 0.01-0.05 parts yeast selenium, 5-15 parts compound amino acids, 1-3 parts vitamin premix, 2-5 parts mineral premix, and 10-30 parts carrier. The probiotics are a compound of *Saccharomyces cerevisiae*, *Bacillus subtilis*, and *Pediococcus lactis*, in a weight ratio of 3:2:1, with a live bacteria count ≥8 billion CFU / g. The yeast selenium contains ≥2000 ppm of organic selenium. This invention features a scientifically formulated and synergistic effect, organically combining probiotics, yeast selenium, and compound amino acids. Probiotics regulate the intestinal microecological balance, yeast selenium enhances the body's antioxidant capacity, and compound amino acids replenish nutritional losses, effectively alleviating stress responses in sows and solving the problem of limited anti-stress effects of single components. Simultaneously, it provides balanced nutrition to meet the nutritional needs of sows at different stages.

The present application relates to a kind of pentose pediococcus and the preparation method of fermented whey.The present application provides a kind of pentose pediococcus IF2, on December 31, 2025, is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No:67584.The strain is isolated from Xinjiang yogurt, with good whey adaptability and flavor promotion capacity.After the single bacteria fermentation whey, the content of dimethyl disulfide, dimethyl trisulfide in whey can be significantly reduced, while the content of acetaldehyde and other flavor compounds is greatly improved, and fermented whey is given apple fragrance.Sensory evaluation shows that the overall preference score of fermented whey can reach 4.6 points, and the flavor is significantly improved.

This invention discloses *Pediococcus lactis* TC-4, which simultaneously degrades nucleosides, purines, and uric acid, and its applications. *Pediococcus lactis* ( Pediococcus acidilactici This invention relates to *Pediococcus lactis* TC-4, with accession number GDMCC No: 67936. *Pediococcus lactis* TC-4 of this invention can efficiently degrade three nucleosides (guanosine, adenosine, and inosine), three purines (guanine, xanthine, and hypoxanthine), and uric acid in vitro. *Pediococcus lactis* TC-4 of this invention can effectively reduce serum uric acid levels in broiler chickens, alleviating and treating hyperuricemia. Compared with traditional chemical drugs for treating hyperuricemia and / or gout, this invention has no toxic side effects on the ecological environment, no residue risk, and is green and safe. This invention has been confirmed at multiple levels, including genetic and animal studies, to have no potential harm to humans, demonstrating its advantages of safety and high efficiency.

This application belongs to the field of microbial technology, and mainly relates to a strain of *Pediococcus lactis* BPA03 and its applications. *Pediococcus lactis* BPA03 is classified and named *Pediococcus lactis*. Pediococcus acidilactici This *Pediococcus lactis* strain BPA03 was deposited on September 28, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 36109. It inhibits skin melanin deposition and improves UV photoaging, suppresses the gene expression levels of immune factors such as IL-1β, IL-6, IL-8, and TNF-α, improves the activities of superoxide dismutase, catalase, and glutathione peroxidase, inhibits vinorelbine-induced neutropenia, and improves the inhibition of immune factor expression induced by vinorelbine, thus exhibiting comprehensive anti-aging effects.

The invention relates to the technical field of microbial culture, and particularly discloses pediococcus pentosaceus NSS0402 and application thereof to improvement of polycystic ovarian syndrome. The invention relates to pediococcus pentosaceus NSS0402, which is preserved in China Center for Type Culture Collection (CCTCC) on July 1, 2024, the address is Wuhan University, Wuhan, China, the pediococcus pentosaceus NSS0402 is named as pediococcus pentosaceus, and the preservation number is CCTCC NO: M 20241421. The pediococcus pentosaceus NSS0402 can effectively improve the polycystic ovarian syndrome and related metabolic level disorder and sex hormone level abnormality symptoms thereof, and can be applied to preparation of products for preventing, relieving or treating the polycystic ovarian syndrome.

The invention provides pediococcus acidilactici with functions of improving emotion and intestinal health and application of the pediococcus acidilactici. The pediococcus acidilactici A25-4 is preserved in Guangdong Microbial Culture Collection Center on May 23, 2025, and the preservation number of the pediococcus acidilactici A25-4 is GDMCC NO: 66384. The pediococcus acidilactici A25-4 has better cholate resistance and artificial gastrointestinal fluid resistance and can produce indole lactic acid ILA at high yield, and the optimal carbon source is fructo-oligosaccharide and galactooligosaccharide. The pediococcus acidilactici A25-4 in-vivo intervention can significantly improve the symptoms of an irritable bowel syndrome model mouse, specifically, the anxiety mood of a tested object is significantly improved; the viscera hypersensitivity of a tested object is obviously relieved; excessive activation of mast cells of a tested object is obviously inhibited; the ILA level in a tested object is obviously improved.

The invention relates to an anti-inflammatory and bacteriostatic oral liquid containing lactic acid bacteria and a preparation method, and belongs to the technical field of oral care, the oral liquid comprises the following raw materials: lactic acid bacteria freeze-dried powder, a plant extract, plant essential oil, a humectant, a flavoring agent, a solubilizer, an antioxidant and deionized water. The lactobacillus paracasei, the pediococcus pentosaceus and the leuconostoc mesenteroides are used as compound lactobacillus freeze-dried powder, adhesion of pathogenic bacteria in an oral cavity and formation of a pathogenic bacteria biological membrane can be effectively inhibited, combination of pathogenic microorganisms and tooth surfaces can be interfered through an immunoregulation mechanism, and therefore the oral liquid is endowed with an excellent bacteriostatic effect; the bletilla striata extract, the clausena lansium extract, the curcuma zedoary extract and the liquorice extract are selected as plant extracts, so that the prepared oral liquid has a prominent anti-inflammatory effect from different aspects of repair promotion, anti-inflammation and bacteriostasis; meanwhile, by compounding the myrtle wood oil, the fructus amomi oil and the sage oil, the oral liquid can also be endowed with a remarkable deodorization effect.

The application discloses Pediococcus pentosaceus SC009 and an application thereof, is preserved in the China General Microbiological Culture Collection Center, and has a preservation time of June 28, 2021 and a preservation number of CGMCC No.22796.The bacteria have the effects of promoting sleep and resisting oxidation, and can be used for preparing sleep-improving and oxidation-resisting food and sleep-disorder treating medicine.In animal experiments, the bacteria can significantly shorten the sleep latency of mice and prolong the sleep time length, improve the sleep quality of mice, significantly improve the total SOD and reduced glutathione content in serum of middle-aged and old rats, reduce the MDA and protein carbonyl content, and have significant antioxidant activity, and can prolong the survival time of old rats.Pediococcus pentosaceus SC009 has the effects of promoting sleep and resisting oxidation, is conducive to market popularization and utilization, and has a broad application prospect.

The invention relates to the technical field of functional foods, and particularly discloses an intestine-moistening and excretion-promoting composition, a compound probiotic preparation and a preparation method of the compound probiotic preparation. The invention provides a composition capable of moistening intestines and promoting excretion. The composition is prepared from the following raw materials in parts by weight: 75 to 150 parts of erythritol, 45 to 90 parts of inulin, 45 to 90 parts of lactitol, 25 to 50 parts of fructus cannabis, 12 to 25 parts of semen raphani, 15 to 30 parts of fructus crataegi, 27 to 55 parts of fructus lycii, 27 to 54 parts of fructo-oligosaccharide, 12 to 25 parts of resistant dextrin and 15 to 33 parts of probiotics. The probiotics are selected from one or more of lactobacillus rhamnosus, pediococcus acidilactici, bifidobacterium animalis, lactobacillus plantarum and lactobacillus reuteri; the invention further provides a compound probiotic preparation prepared from the intestine moistening and excretion promoting composition. The composite probiotic agent provided by the invention can regulate the balance of intestinal flora and promote gastrointestinal motility, and has very good intestine moistening and excretion promoting effects.

This invention discloses bacterial strains, compound microbial agents, and a method for rapidly preparing Luocheng rice noodles, relating to the field of food processing technology. The bacterial strains used for preparing Luocheng rice noodles include *Geotrichum candida* (…). Galactomyces candidum ) Mei3303.1, Pediococcus acidilactici ( Pediococcus acidilactici Mei.1103.1 and Lactobacillus paracasei ( Lactobacillus paracasei Both Mei1104.02 and Mei1104.02 have been deposited at the China General Microbiological Culture Collection Center. The beneficial effects of this invention are that by strengthening the fermentation process with compound microbial agents, it can improve fermentation efficiency, shorten fermentation time, inhibit the growth of other miscellaneous bacteria, and improve the flavor stability and safety of rice noodles.

This invention belongs to the field of microbial technology, and relates to a *Pediococcus pentosacchari* strain derived from geese, its isolation and screening method, and its application. The *Pediococcus pentosacchari* strain is *Pediococcus pentosacchari*. Pediococcus pentosaceus L2, deposited at the Guangdong Provincial Microbial Culture Collection Center, accession number GDMCC No:67207. This invention, *Pediococcus pentosaceus* L2, was isolated and screened from the cecum of healthy Magang geese. Its source is reliable and readily available, possessing safety and probiotic properties. It exhibits good antibacterial activity against *Clostridium perfringens*, demonstrating excellent probiotic potential for application in feed additives, probiotic preparations, and medications for treating geese infected with *Clostridium perfringens*.

The application belongs to the technical field of microbial application, and relates to a chiral L-lactic acid production engineering bacterium capable of selectively degrading racemic D-lactic acid and application of the chiral L-lactic acid production engineering bacterium. Pediococcus acidilactici The strain is classified and named as Pediococcus acidilactici LJ2071 and is preserved in the China Center for Type Culture Collection, has a preservation number of CCTCC M 20251230 and a preservation date of May 30, 2025. The strain has the ability to efficiently metabolize various types of biomass-derived monosaccharides and synthesize high-concentration and high-chirality L-lactic acid, has a certain degradation capacity for D-lactic acid contained in the fermentation raw material itself, and can use raw material containing a certain amount of racemic lactic acid to produce high-chirality L-lactic acid. When the concentration of racemic D-lactic acid in the fermentation liquor is not more than 1.5 g / L, the chirality of the L-lactic acid product is greater than 99.5%, and the L-lactic acid product can be used as a poly-lactic acid material polymerization monomer.

The present application relates to the technical field of microbial strains and the technical field of soybean seed coat fermentation, in particular to a Pediococcus sp. of Pteropus sp. and application thereof in improving the flavor of soybean seed coat, wherein the Pediococcus sp. of Pteropus sp. is Pediococcus sp. of Pteropus sp. BL-2 (Lactococcus petauri BL-2) , which is preserved in China Center for Type Culture Collection with a preservation number of CCTCC NO: M 20252253. The Pediococcus sp. of Pteropus sp. BL-2 of the present application not only has significant antioxidant activity, but also can significantly increase the content of 3-hydroxy-2-butanone (acetoin) with a pleasant buttery flavor in soybean seed coat and significantly reduce the content of isovaleric acid, 2-methyl-2-pentenal and dimethyl disulfide and other substances with strong irritating odor after fermentation of soybean seed coat, thereby effectively improving the flavor of soybean seed coat.

The application provides a Pediococcus pentosaceus strain A20001 with anti-inflammatory and 5-HT secretion functions, and a derivative product and application thereof, and belongs to the technical field of functional microorganisms.The strain A20001 is isolated from the excrement of a healthy centenarian in Guangxi, and is identified as Pediococcus pentosaceus through molecular identification and morphological identification.The Pediococcus pentosaceus strain A20001 has the functions of anti-inflammation and 5-HT secretion, and provides a new idea for the treatment of diseases related to intestinal inflammation and / or depression caused by insufficient 5-HT secretion.

The invention belongs to the field of feed chemistry and bioengineering, and discloses an intestinal tract health-care probiotic pig feed and a preparation method thereof. The feed is prepared by taking chitosan which is condensed and modified by food-grade lactic acid oligomers and sodium 2, 3-dihydroxybutyrate as main components, and matching bacillus licheniformis, pediococcus acidilactici, bifidobacterium and beer yeast. The modified chitosan forms a compact carrier membrane through molecular condensation, so that the damage of gastric acid and cholate can be effectively resisted, and the survival rate of probiotics in intestinal tracts is increased; the 2, 3-sodium dihydroxybutyrate is metabolized in intestinal tracts to generate butyrate, so that the synthesis of short-chain fatty acid is promoted, the energy metabolism of epithelial cells is enhanced, and the intestinal mucosal barrier is repaired. The feed provided by the invention has high stability and good biological activity, and can effectively improve intestinal flora balance and nutrient absorption function of pigs.

A method for producing fermented shiitake mushroom sauce according to an embodiment includes adding lactose and sucrose to shiitake mushroom concentrate followed by inoculation of Pediococcus pentosaceus strain or Lactobacillus acidophilus strain and fermentation to prepare lactic acid bacteria fermented product of shiitake mushroom, and mixing the lactic acid bacteria fermented product of shiitake mushroom prepared above with hot pepper extract, garlic extract, onion extract, and shiitake mushroom block, water, salt, lemongrass, and coriander, and the present invention also relates to fermented shiitake mushroom sauce produced by the aforementioned method.

The invention discloses a method for degrading African swine fever viruses by fermenting pennisetum sinese with compound probiotics, which comprises the following steps: crushing a pennisetum sinese raw material polluted by the African swine fever viruses; the preparation method comprises the following steps: inoculating a compound probiotic leavening agent containing six specific strains (pichia membranaefaciens C200-1, brevibacillus reuteri RF10-5, pediococcus acidilactici, lactobacillus plantarum, lactobacillus buchneri and bifidobacterium), and fermenting for 6-14 days at 20-40 DEG C under a closed condition. By means of the fermentation process, polluted African swine fever viruses in materials can be effectively degraded, and q-PCR detection shows negative on the seventh day. The method is specially used for solving the problem of African swine fever virus pollution, is clear in effect, green, safe and easy to implement, and provides a feed link solution for prevention and control of African swine fever.

This invention provides a solid-state fermented oat postbiotic that can promote weight loss and its preparation method. Specifically, it is obtained by solid-state fermentation of oat raw materials using a four-component compound bacterial powder. The four-component compound bacterial powder is made from *Lactobacillus paracasei* IOB413, *Lactobacillus casei* IOB-P9, *Lactobacillus plantarum* IOB602, and *Pediococcus lactis* IOB701, wherein the mass ratio of *Lactobacillus paracasei* IOB413, *Lactobacillus casei* IOB-P9, *Lactobacillus plantarum* IOB602, and *Pediococcus lactis* IOB701 is (1~2):(1~2):(1~2):(1~3). The solid-state fermented oat postbiotic provided by this invention shows great promise for application in the preparation of foods that prevent obesity, promote weight loss, alleviate hyperglycemia and hyperlipidemia, and promote bowel movements.

The invention belongs to the technical field of fermented feed, and particularly relates to a compound lactic acid bacterium agent for producing yak feed by fermenting highland barley vinasse, and application and an application method thereof. The invention provides a compound lactic acid bacterium agent for producing yak feed by fermenting highland barley vinasse, which is prepared by compounding bacterium liquid of lactobacillus plantarum, bacterium liquid of lactobacillus buchneri, bacterium liquid of lactobacillus fermentum and bacterium liquid of pediococcus pentosaceus according to the volume ratio of (2-4): (1-3): (1-3): (0.5-2). Cellulose components in the raw materials such as the highland barley vinasse, the alfalfa hay and the rapeseed cake can be fully decomposed, so that the utilization rate of the raw materials is greatly improved, and meanwhile, the content of nutritional ingredients such as crude protein in the fermented feed and the oxidation resistance of the feed are improved; a new way is provided for development of the yak industry and improvement of the additional value of the highland barley vinasse.

The invention belongs to the technical field of microorganisms, and relates to pediococcus acidilactici and application thereof. The preservation number of the pediococcus acidilactici AK-RS1 is CCTCC NO: M2025755, the pediococcus acidilactici AK-RS1 is excellent in acid resistance, alkali resistance, cholate resistance and trypsin resistance, the adhesion rate of the pediococcus acidilactici AK-RS1 to duck intestinal epithelial cells reaches 14.6%, and the pediococcus acidilactici AK-RS1 is sensitive to common antibiotics and high in safety.

The invention belongs to the field of microorganisms, and particularly relates to screening of lactic acid bacteria capable of relieving ozostomia and application of oral cavity probiotic characteristics of the lactic acid bacteria. The invention provides pediococcus acidilactici ZJUIDS-C004, and the preservation number of the pediococcus acidilactici ZJUIDS-C004 is CGMCC (China General Microbiological Culture Collection Center) NO. 34145. The pediococcus acidilactici ZJUIDS-C004 can be used for inhibiting the growth of halitosis pathogenic bacteria with fusobacterium nucleatum (F.n), and the pediococcus acidilactici ZJUIDS-C004 has an inhibiting effect on a biological membrane formed by the halitosis pathogenic bacteria; the strain is used for solving oral health problems and relieving and improving halitosis.

This invention relates to a traditional Chinese medicine composition containing celeon bone and its use in improving joint aging and injury. It belongs to the field of traditional Chinese medicine processing technology. The preparation method of celeon bone in the traditional Chinese medicine composition includes the following steps: (1) celeon bone is pulverized to obtain bone powder; (2) the bone powder is added to water and enzymatically hydrolyzed with protease, then inactivated to obtain an enzymatic hydrolysate; (3) microorganisms are added to the enzymatic hydrolysate for fermentation to obtain a fermentation broth; (4) the fermentation broth is inactivated, and solid-liquid separation is performed to obtain a clear liquid; (5) the clear liquid is dried to obtain the final product. The microorganisms include at least one of Bacillus subtilis, Lactobacillus helveticus, Pediococcus pentosaceus, Saccharomyces cerevisiae, Lactobacillus paracasei, and Lactobacillus plantarum. The celeon bone powder prepared by this invention can exert a good anti-inflammatory effect at low doses and can be used to prepare drugs for osteoarthritis caused by joint aging or injury, especially for treating osteoarthritis, rheumatoid arthritis, and other osteoarthritis. It also has good safety and broad application prospects.

The invention discloses a method for producing gamma-aminobutyric acid through double-bacterium synergistic fermentation of lignocellulose hydrolysate, and belongs to the technical field of microbial engineering. The method comprises the following steps: constructing a recombinant pediococcus acidilactici (Pediococcus acidilactici FR-XY) engineering bacterium, and constructing a recombinant pediococcus acidilactici (Pediococcus acidilactici) FR-XY; the method comprises the following steps: carrying out staged fermentation culture on lactobacillus hilgardii FR-1012 and recombinant pediococcus acidilactici FR-XY by utilizing lignocellulose hydrolysate, so as to obtain mixed fermentation liquor; centrifuging the mixed fermentation liquor, collecting mixed thalli, resuspending the mixed thalli in a conversion solution containing L-glutamic acid and coenzyme 5-phosphopyridoxal, and carrying out whole-cell conversion reaction to obtain a conversion solution containing gamma-aminobutyric acid. According to the method, the lignocellulose hydrolysate can be utilized for double-bacterium synergistic fermentation, and full utilization of a multi-element carbon source in the lignocellulose hydrolysate and efficient synthesis of gamma-aminobutyric acid are achieved.

The present application belongs to the field of life science, and particularly relates to a functional probiotic strain Pediococcus pentosaceus. The Pediococcus pentosaceus WMU002 strain of the present application is derived from human body, and is high in safety after screening, domestication and verification. The Pediococcus pentosaceus WMU002 strain selected by the present application can obviously improve the motor disorder caused by Parkinson's disease and improve the behavior ability, overcome the defects and deficiencies of the prior art, and creatively apply the Pediococcus pentosaceus to the prevention and treatment of Parkinson's disease, and further develop a probiotic preparation for preventing or treating Parkinson's disease. The Pediococcus pentosaceus preparation composition of the present application can be used as a drug for preventing and treating Parkinson's disease, has no toxic side effects, and can be used for the auxiliary treatment of clinical Parkinson's disease patients. The present application has good social and economic benefits, and is worth popularization and application.

The present application discloses a lactic acid pediococcus SWU-HX39 with the function of reducing uric acid, and the classification name is lactic acid pediococcus (Pediococcus acidilactici) Pediococcus acidilactici ), which is preserved in the China General Microbiological Culture Collection Center, with the preservation number of CGMCC No.33055, the preservation date of December 13, 2024, and the preservation address of No.3, Xili, Beichen West Road, Chaoyang District, Beijing. The lactic acid pediococcus SWU-HX39 can relieve the kidney damage caused by high uric acid, reduce the synthesis of uric acid, lower the concentration of uric acid in blood, improve the excretion of uric acid in the body, reduce the reabsorption of uric acid in the body, and achieve the effect of reducing uric acid. In addition, SWU-HX39 can reduce the expression of LPS and the expression of inflammatory factors IL-1beta, IL-6 and TNF alpha. That is, it has the functions of anti-inflammation and relieving liver inflammation, and can also increase the content of SCFAs in the body of patients with high uric acid, especially propionic acid, so as to reduce the uric acid level and improve the abnormal uric acid content.