130 results about "Pediococcus sp." patented technology

The invention discloses pediococcus acidilactici and application thereof, and relates to the technical field of microorganisms. The pediococcus acidilactici is pediococcus acidilactici Mei.1103.1, the preservation unit is China General Microbiological Culture Collection Center, the preservation number is CGMCC NO.32564, the preservation date is November 11, 2024, the preservation address is Institute of Microbiology, Chinese Academy of Sciences, No. 3, No.1 Yard, Beichen West Road, Chaoyang District, Beijing, and the preservation number is CGMCC NO.32564. The pediococcus acidilactici Mei.1103.1 is CGMCC NO.32564. The pediococcus acidilactici Mei.1103.1. The invention also provides application of the fermented dry rice flour in preparation of products for reducing uric acid, preventing / treating hyperuricemia, regulating immunity, preventing / treating kidney injury and preventing / treating fatty liver and fermented dry rice flour. The bacterium can reduce uric acid and relieve hyperuricemia; regulating blood fat; kidney and liver injuries caused by hyperuricemia are repaired; the content of volatile flavor compounds in the fermented dry rice flour is increased.

The invention discloses pediococcus acidilactici NDF12 and application thereof, the pediococcus acidilactici NDF12 is preserved in Guangdong Microbial Culture Collection Center on January 8, 2025, is called GDMCC for short, and the preservation number is GDMCC NO: 65732. The invention further discloses a preparation method of the pediococcus acidilactici NDF12. The strain is derived from Chinese local traditional dairy products, phenotype and genotype safety evaluation proves that the strain is safe and non-toxic, has excellent fermentation characteristics and probiotic characteristics, and can be used as a leavening agent for producing yoghourt. The bacterial strain also has gastrointestinal fluid endurance capacity, adhesion capacity, bacteriostatic activity, antioxidant activity, cholesterol lowering activity and blood sugar lowering activity, and has great application prospects in the fields of foods, medicines, feeds and the like.

The present invention provides a Pediococcus pentosaceus ( Pediococcus pentosus ) strain ZPP083, which is deposited with the General Microbiology Center of the China National Center for Microbiological Culture Collection under the CGMCC No. 31944. The Pediococcus pentosaceus provided by the present invention has a strong antibacterial effect and produces a novel Class IIa bacteriocin with acid, heat, and protease resistance. The present invention also constructs a genetically engineered bacterium using this bacteriocin, increasing its expression.

The invention discloses pediococcus acidilactici screening and application of pediococcus acidilactici in reducing allergenicity of whey and improving flavor, and belongs to the technical field of whey processing. The invention provides a Pediococcus acidilactici BC37, and the preservation number of the Pediococcus acidilactici BC37 is GDMCC No: 66262. The Pediococcus acidilactici BC37 can be used for preparing a Pediococcus acidilactici strain. When the pediococcus acidilactici BC37 is used for preparing the fermented whey, beta-lactoglobulin and lactose in the whey can be effectively degraded, and the degradation rates respectively reach 49.93% and 15.74%; meanwhile, after whey is fermented by the pediococcus acidilactici BC37, high-content flavor substances such as furfural, butyric acid and ethyl caprate are generated. Therefore, the pediococcus acidilactici BC37 provided by the invention has a great industrial application prospect in preparation of fermented whey products with low sensitization and unique flavor.

This invention belongs to the field of microbial technology, specifically relating to a strain of *Pediococcus pentosaceus* SUN02 with acetylcholinesterase inhibitory activity and its applications. This *Pediococcus pentosaceus* SUN02 is deposited at the China General Microbiological Culture Collection Center (CGMCC) with accession number CGMCC No. 29705. The *Pediococcus pentosaceus* SUN02 provided by this invention exhibits strong acid and bile salt resistance, good tolerance in simulated gastric and intestinal fluids, and can successfully reach the human intestine. *Pediococcus pentosaceus* SUN02, in its bacterial suspension and inactivated cells, possesses strong acetylcholinesterase inhibitory activity, produces γ-aminobutyric acid (GABA), and has antioxidant and other probiotic functions. Its application in probiotic products may help improve Alzheimer's disease, enhance learning and memory abilities, regulate mood, and improve sleep.

The invention relates to pediococcus acidilactici, in particular to pediococcus acidilactici TCI550 with the preservation number of DSM34536, and the pediococcus acidilactici TCI550 has the preservation number of DSM34536. In addition, the pediococcus acidilactici TCI550 and / or metabolites thereof can be suitable for preparing a composition for nerve health care and / or cognition improvement.

The invention relates to the technical field of functional microbial preparations, in particular to a biological preparation for relieving intestinal discomfort caused by alcohol and a preparation method and application thereof.The main technical scheme is that the biological preparation is prepared from, by weight, 5-20 parts of bacillus coagulans, 10-30 parts of pediococcus pentosaceus, 5-10 parts of lactobacillus rhamnosus and 0-20 parts of saccharomycetes. 0-5 parts of bifidobacterium longum and 0-5 parts of lactococcus lactis. By constructing an alcohol metabolism-intestinal protection dual-function synergistic system, specific florae such as bacillus coagulans, pediococcus pentosaceus and lactobacillus rhamnosus are scientifically compatible with functional components such as inulin and L-cysteine, alcohol is efficiently metabolized, and a carbon source is generated; the technical problems of low metabolic efficiency, weak intestinal protection and serious gastric acid inactivation of a traditional product are comprehensively solved.

The invention belongs to the technical field of functional microorganisms, and provides pediococcus acidilactici MR21 and application thereof. The pediococcus acidilactici MR21 provided by the invention is preserved in the China General Microbiological Culture Collection Center (CGMCC) on December 3, 2024, and the preservation number is CGMCC NO. 32896. The pediococcus acidilactici MR21 disclosed by the invention has efficient in-vitro cholesterol removal capacity, excellent safety and remarkable probiotic characteristics, and has the effects of restoring liver functions, reducing liver fat accumulation and regulating expression of fat and cholesterol metabolism related genes by remarkably reducing the content of serum total cholesterol and low-density lipoprotein cholesterol. Therefore, the function of relieving hypercholesterolemia is achieved.

This invention belongs to the field of food fermentation technology, and specifically relates to a compound probiotic agent and its application in the preparation of fermented soy milk. This invention provides a compound probiotic agent composed of *Lactobacillus fermentum* NCPS LF01, *Pediococcus pentosaceus* NCPS PPE01, and *Lactobacillus acidophilus* NCPS LA01 in a volume ratio of 1-2:1:1, and applies this compound probiotic agent to the preparation of soy products, especially fermented soy milk. The beneficial effects of this invention are that fermented soy milk prepared using this compound probiotic agent has a rich flavor, and the total flavonoid and total phenolic content, as well as the in vitro DPPH free radical scavenging rate, are significantly superior to those of ordinary commercially available strains or other strains. In summary, this compound probiotic agent can effectively improve the retention level of active ingredients and antioxidant capacity of fermented soy milk, and has outstanding application value.

The invention discloses pediococcus acidilactici and application thereof in preparation of a medicine for preventing or treating diarrhea of yak calves, and belongs to the technical field of microorganisms. The pediococcus acidilactici is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M20252012, and the preservation date is September 12, 2025. The strain has remarkable bacteriostatic activity on yak-derived multi-drug-resistant escherichia coli (the accession number of NCBI is PP859186). After the probiotic preparation is orally taken, the yak calf diarrhea induced by escherichia coli can be effectively relieved, the diarrhea rate and the inflammatory factor level are remarkably reduced, the oxidation resistance is improved, the flora structures of intestinal bacteria and fungi are adjusted, and the micro-ecological balance is restored. The invention provides a safe, green and efficient alternative antibody product which is suitable for the plateau yak breeding industry.

The microorganism strain Pediococcus acidilactici TAK 589 CoccobEst is a new antimicrobial and antioxidant probiotic, CoccobEst inhibits the growth of the enteropathogens L. monocytogenes, E. coli, S. enteritidis, S. typhimurium, S. sonnei, S. aureus, E. faecalis and C. sakazakii, but does not inhibit lactobacilli of natural intestinal microbiota. The strain's antimicrobial properties are enhanced by periplasmic peptidoglycan hydrolases with proteolytic activity. CoccobEst is used as a zootechnieai feed additive to prevent bacterial infections in the gastrointestinal tract of farm animals and pets and to prevent and reduce diarrhea. CoccobEst has highly active antioxidant defense system, increasing the redox activity of glutathione and reducing oxidative stress in cells. Therefore, CoccobEst is used as a food supplement or functional food for humans to prevent bacterial infections of the gastrointestinal tract and to prevent and reduce oxidative stress. In addition, CoccobEst is used as a starter culture in fermentation of vegetables.

This invention discloses a multifunctional Pediococcus pentosaccharide strain and its applications. Pediococcus pentosaceus The strain, named *Pediococcus pentosaceus* A07, has the accession number CCTCC NO: M 2025777 and is deposited at the China Center for Type Culture Collection (CCTCC), located at Wuhan University, No. 299 Bayi Road, Wuchang District, Wuhan City, Hubei Province. This strain is capable of degrading nitrite. Using *Pediococcus pentosaceus* A07 to reduce nitrite content can produce high-quality pickles with good flavor and texture, low nitrite content, and high viable cell count. The *Pediococcus pentosaceus* A07 provided by this invention also possesses cholesterol-lowering, zinc protoporphyrin-forming, antibacterial, and antioxidant capabilities, and produces a high biofilm.

The invention discloses a pediococcus pentosaceus MDL511, which is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.35201, the preservation date is July 11, 2025, and the classification name of the strain is pediococcus pentosaceus. The pediococcus pentosaceus MDL511 has the advantages that the preservation number is CGMCC No.35201, the preservation number is CGMCC No.35201, the preservation date is July 11, 2025, and the classification name of the strain is pediococcus pentosaceus. The pediococcus pentosaceus MDL511 disclosed by the invention can be used for remarkably reducing weight gain and fat growth of mice caused by high fat diet, reducing serum cholesterol, LDL-C (Low Density Lipoprotein Cholesterol) and ALT (Atomic Lymphocyte Transferase) levels and remarkably improving hepatic lesions and fat accumulation caused by high fat diet, so that the MDL511 has a blood fat reducing effect, can be used for preparing blood fat reducing products and weight losing products and has a good development prospect.

The invention relates to the technical field of microbial food fermentation, and particularly discloses pediococcus acidilactici RM1, a separation method and application, and the pediococcus acidilactici RM1 is characterized in that the preservation number of the pediococcus acidilactici RM1 is GDMCC NO.66765; the preservation unit of the pediococcus acidilactici RM1 is Guangdong Microbial Culture Collection Center; the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1, and the preservation name of the pediococcus acidilactici RM1 is pediococcus acidilactici RM1. The preservation time of the pediococcus acidilactici RM1 is July 28, 2025. The method has the characteristics of bright red color, difficulty in deterioration during storage and ideal quality and flavor.

The invention discloses a probiotic composition, fermented yoghurt and application of the probiotic composition and the fermented yoghurt in improving related indexes of athletes. The probiotic composition comprises bacillus subtilis SP-8-5, lactobacillus plantarum YM-4-3, lactobacillus plantarum AY01 and pediococcus acidilactici LH01. The composition of intestinal microbial populations can be adjusted through a specific compounding method, the abundance of harmful bacteria is reduced, the abundance of beneficial bacteria is improved, the immunity of intestinal tracts is enhanced, and the integrity of intestinal barriers of athletes is maintained. Meanwhile, the composition has a positive improvement effect on related exercise indexes such as plasma amino acid, excrement metabolites and exercise performance, and can be used as an effective exercise supplement to be applied to athletes.

The invention relates to a compound vomitoxin detoxification agent as well as a preparation method and application thereof, and belongs to the field of feed additives. The compound vomitoxin detoxification agent comprises the following components: detoxification bacteria, glucose oxidase, an adsorbent and a eucommia ulmoides extract, the detoxification bacteria are lactobacillus plantarum, pediococcus pentosaceus and saccharomyces cerevisiae. The compound vomitoxin detoxification agent can effectively reduce DON toxins in feed, improve the antioxidant capacity of animals, improve immunity, regulate intestinal flora and promote animal growth.

The invention provides pediococcus acidilactici SCFF996 with high EutE enzyme activity and application of the pediococcus acidilactici SCFF996 in a hangover alleviating and liver protecting product, and belongs to the technical field of microorganisms. Wherein the pediococcus acidilactici SCFF996 is preserved in the China General Microbiological Culture Collection Center, and the preservation number of the pediococcus acidilactici SCFF996 is CGMCC (China General Microbiological Culture Collection Center) No. 33405. The pediococcus acidilactici SCFF996 provided by the invention has very good EutE enzyme activity, ethanol tolerance, acid resistance and cholate resistance, can inhibit pathogenic bacteria, is easy to culture and high in reproduction speed, and has remarkable advantages in production of alcohol effect dispelling and liver protecting products.

This invention discloses a functional feed for sows to combat stress and its preparation method. The functional feed for sows to combat stress comprises the following components by weight: 700-850 parts basal feed, 0.5-3 parts probiotics, 0.01-0.05 parts yeast selenium, 5-15 parts compound amino acids, 1-3 parts vitamin premix, 2-5 parts mineral premix, and 10-30 parts carrier. The probiotics are a compound of *Saccharomyces cerevisiae*, *Bacillus subtilis*, and *Pediococcus lactis*, in a weight ratio of 3:2:1, with a live bacteria count ≥8 billion CFU / g. The yeast selenium contains ≥2000 ppm of organic selenium. This invention features a scientifically formulated and synergistic effect, organically combining probiotics, yeast selenium, and compound amino acids. Probiotics regulate the intestinal microecological balance, yeast selenium enhances the body's antioxidant capacity, and compound amino acids replenish nutritional losses, effectively alleviating stress responses in sows and solving the problem of limited anti-stress effects of single components. Simultaneously, it provides balanced nutrition to meet the nutritional needs of sows at different stages.

The invention belongs to the technical field of microecological preparations, and provides an animal microecological preparation for promoting intestinal health and a preparation method thereof. The preparation method comprises the following steps: firstly, respectively culturing lactobacillus reuteri and pediococcus acidilactici in an MRS culture medium, culturing bacillus subtilis in an LB culture medium, and culturing saccharomyces cerevisiae in a YPD culture medium to obtain high-activity bacterial liquid; the method comprises the following steps: mixing a multi-strain bacterial liquid with a substrate containing soybean meal hydrolysate, wheat bran and the like, and carrying out staged fermentation, so as to realize metabolism synergy among different strains; then, mixing the fermentation product with skimmed milk powder, maltodextrin and glycerol, and performing freeze drying to prepare a multi-strain probiotic preparation; and finally, mixing the probiotic preparation with nisin, pediococcus acidilactici, fructo-oligosaccharide and xylooligosaccharide, and performing vacuum drying to prepare the microecological preparation, so that the microecological preparation can effectively regulate the microecological balance of animal intestinal tracts, enhance the health level and reduce the use of antibiotics, and has remarkable economic and ecological benefits.

The present application relates to a kind of pentose pediococcus and the preparation method of fermented whey.The present application provides a kind of pentose pediococcus IF2, on December 31, 2025, is preserved in Guangdong Microbial Culture Collection Center, and the preservation number is GDMCC No:67584.The strain is isolated from Xinjiang yogurt, with good whey adaptability and flavor promotion capacity.After the single bacteria fermentation whey, the content of dimethyl disulfide, dimethyl trisulfide in whey can be significantly reduced, while the content of acetaldehyde and other flavor compounds is greatly improved, and fermented whey is given apple fragrance.Sensory evaluation shows that the overall preference score of fermented whey can reach 4.6 points, and the flavor is significantly improved.

This invention discloses *Pediococcus lactis* TC-4, which simultaneously degrades nucleosides, purines, and uric acid, and its applications. *Pediococcus lactis* ( Pediococcus acidilactici This invention relates to *Pediococcus lactis* TC-4, with accession number GDMCC No: 67936. *Pediococcus lactis* TC-4 of this invention can efficiently degrade three nucleosides (guanosine, adenosine, and inosine), three purines (guanine, xanthine, and hypoxanthine), and uric acid in vitro. *Pediococcus lactis* TC-4 of this invention can effectively reduce serum uric acid levels in broiler chickens, alleviating and treating hyperuricemia. Compared with traditional chemical drugs for treating hyperuricemia and / or gout, this invention has no toxic side effects on the ecological environment, no residue risk, and is green and safe. This invention has been confirmed at multiple levels, including genetic and animal studies, to have no potential harm to humans, demonstrating its advantages of safety and high efficiency.

The invention provides pediococcus acidilactici HC-2, a fermentation method for fermenting radix astragali through the pediococcus acidilactici HC-2 and application, and relates to the technical field of biological medicine, the pediococcus acidilactici HC-2 is preserved in the China Center for Type Culture Collection on January 20, 2025; the preservation number is CCTCC (China Center For Type Culture Collection) CNO: M 2025183; the preservation address is Wuhan University, Wuhan, China; the Pediococcus acidilactici HC-2 is named as Pediococcus acidilactici HC-2 in taxonomy.

This application belongs to the field of microbial technology, and mainly relates to a strain of *Pediococcus lactis* BPA03 and its applications. *Pediococcus lactis* BPA03 is classified and named *Pediococcus lactis*. Pediococcus acidilactici This *Pediococcus lactis* strain BPA03 was deposited on September 28, 2025, at the China General Microbiological Culture Collection Center (CGMCC), located at No. 3, Courtyard 1, Beichen West Road, Chaoyang District, Beijing, with accession number CGMCC No. 36109. It inhibits skin melanin deposition and improves UV photoaging, suppresses the gene expression levels of immune factors such as IL-1β, IL-6, IL-8, and TNF-α, improves the activities of superoxide dismutase, catalase, and glutathione peroxidase, inhibits vinorelbine-induced neutropenia, and improves the inhibition of immune factor expression induced by vinorelbine, thus exhibiting comprehensive anti-aging effects.

The invention discloses pediococcus pentosaceus TRM54998 with broad-spectrum antibacterial activity and application of the pediococcus pentosaceus TRM54998, and belongs to the field of microorganisms. The strain is preserved in the China Center for Type Culture Collection (CCTCC) on June 04, 2024, and the preservation number is CCTCC NO: M 20241142. It is proved that the strain has good acid resistance and bile salt resistance and can grow in the environment with the bovine bile salt concentration being 0.1-0.2% (w / v) or in the pH value range being 3-7; the fermentation supernatant has an inhibition effect on nine pathogenic bacteria such as salmonella and the like, and the antibacterial effect is stable; meanwhile, experiments prove that the pediococcus pentosaceus TRM54998 has no wide drug resistance, can relieve the problems of aggravated drug resistance, damage to microbial ecological balance and the like caused by antibiotic abuse, provides a strain resource for preparing a biological bacteriostatic agent or an intestinal probiotic agent, and has a wide application prospect.

The invention relates to the technical field of microbial culture, and particularly discloses pediococcus pentosaceus NSS0402 and application thereof to improvement of polycystic ovarian syndrome. The invention relates to pediococcus pentosaceus NSS0402, which is preserved in China Center for Type Culture Collection (CCTCC) on July 1, 2024, the address is Wuhan University, Wuhan, China, the pediococcus pentosaceus NSS0402 is named as pediococcus pentosaceus, and the preservation number is CCTCC NO: M 20241421. The pediococcus pentosaceus NSS0402 can effectively improve the polycystic ovarian syndrome and related metabolic level disorder and sex hormone level abnormality symptoms thereof, and can be applied to preparation of products for preventing, relieving or treating the polycystic ovarian syndrome.

The invention provides pediococcus acidilactici with functions of improving emotion and intestinal health and application of the pediococcus acidilactici. The pediococcus acidilactici A25-4 is preserved in Guangdong Microbial Culture Collection Center on May 23, 2025, and the preservation number of the pediococcus acidilactici A25-4 is GDMCC NO: 66384. The pediococcus acidilactici A25-4 has better cholate resistance and artificial gastrointestinal fluid resistance and can produce indole lactic acid ILA at high yield, and the optimal carbon source is fructo-oligosaccharide and galactooligosaccharide. The pediococcus acidilactici A25-4 in-vivo intervention can significantly improve the symptoms of an irritable bowel syndrome model mouse, specifically, the anxiety mood of a tested object is significantly improved; the viscera hypersensitivity of a tested object is obviously relieved; excessive activation of mast cells of a tested object is obviously inhibited; the ILA level in a tested object is obviously improved.

The invention relates to an anti-inflammatory and bacteriostatic oral liquid containing lactic acid bacteria and a preparation method, and belongs to the technical field of oral care, the oral liquid comprises the following raw materials: lactic acid bacteria freeze-dried powder, a plant extract, plant essential oil, a humectant, a flavoring agent, a solubilizer, an antioxidant and deionized water. The lactobacillus paracasei, the pediococcus pentosaceus and the leuconostoc mesenteroides are used as compound lactobacillus freeze-dried powder, adhesion of pathogenic bacteria in an oral cavity and formation of a pathogenic bacteria biological membrane can be effectively inhibited, combination of pathogenic microorganisms and tooth surfaces can be interfered through an immunoregulation mechanism, and therefore the oral liquid is endowed with an excellent bacteriostatic effect; the bletilla striata extract, the clausena lansium extract, the curcuma zedoary extract and the liquorice extract are selected as plant extracts, so that the prepared oral liquid has a prominent anti-inflammatory effect from different aspects of repair promotion, anti-inflammation and bacteriostasis; meanwhile, by compounding the myrtle wood oil, the fructus amomi oil and the sage oil, the oral liquid can also be endowed with a remarkable deodorization effect.

The invention relates to the technical field of food processing, in particular to a processing method for cooked mutton, which comprises the following steps: obtaining a fresh mutton raw material; performing pretreatment before fermentation on the fresh mutton raw material; adding a compound bacteria solution into the pretreated fresh mutton raw material, and fermenting to hydrolyze goaty-flavor substances in the mutton to obtain fermented mutton; immersing the fermented mutton into a composite gel solution and carrying out vacuum impregnation so as to selectively remove fermented free mutton smell substances, so as to obtain mutton smell removed mutton; and pickling the mutton with the removed mutton smell with ingredients, and cooking the mutton at 80-85 DEG C for 10-15 minutes to obtain a cooked mutton finished product, wherein the compound bacteria liquid consists of staphylococcus carnosus, pediococcus pentosaceus, lactococcus lactis and a calcium chloride solution. According to the invention, mutton-smell-causing short-chain branched fatty acid in mutton is degraded by a microbial mutton-smell-reducing method, and long-chain branched fatty acid with physiological activity is retained at the same time.

The invention belongs to the field of food fermentation, and particularly relates to a pediococcus pentosaceus strain, porphyra haitanensis-pediococcus pentosaceus fermentation liquor and application thereof in enhancing the intestinal barrier function. A strain of pediococcus pentosaceus is obtained through screening, the pediococcus pentosaceus and porphyra haitanensis are jointly fermented, a fermented product with the function of enhancing the intestinal barrier can be obtained, specifically, the expression level of ZO-1, occuldin, claudin-1 and claudin-4 tight junction protein related genes can be up-regulated, and the function of protecting the intestinal barrier is achieved. According to the fermentation strain and the fermentation method provided by the invention, the original biological activity and nutritional value of the porphyra haitanensis can be improved, healthy seaweed food capable of enhancing the intestinal barrier activity is developed, diversification of seaweed deep processing products and multi-level processing technologies are promoted, and rapid development of the seaweed deep industry in China is promoted.

The application discloses a pediococcus acidilactici, a bacterial agent, a microbial composition and application and products thereof for reducing uric acid, and belongs to the technical field of microorganisms. The application provides a pediococcus acidilactici with a preservation number of GDMCC No: 67942, and a 16S rDNA sequence of the pediococcus acidilactici is shown as SEQ ID NO. 1. The strain can degrade purine nucleosides, inhibit xanthine oxidase, and has strong antioxidant activity; can be efficiently fermented in a plantago major plant base to prepare a live / inactivated bacterial agent and a microbial composition. Animal experiments prove that the strain and the plantago major fermentation product can significantly reduce blood uric acid of a hyperuricemia model mouse, improve liver, kidney and intestinal injury, reduce inflammation, increase short-chain fatty acid level and regulate intestinal flora, and the inactivated fermentation product has better effect. The product can be prepared into food, health products or drugs, and is used for reducing uric acid and assisting in reducing uric acid, is safe and effective, and is suitable for long-term intervention.