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8 results about "Bacteriocin" patented technology

Bacteriocins are proteinaceous or peptidic toxins produced by bacteria to inhibit the growth of similar or closely related bacterial strain(s). They are similar to yeast and paramecium killing factors, and are structurally, functionally, and ecologically diverse. Applications of bacteriocins are being tested to assess their application as narrow-spectrum antibiotics.

Method for preparing allergic rhinitis spray from umbilical cord mesenchymal stem cell exosome

The invention relates to the technical field of rhinitis spray preparation, in particular to a method for preparing allergic rhinitis spray from umbilical cord mesenchymal stem cell exosomes, which comprises the following steps: 1, umbilical cord treatment; 2, culturing umbilical cord mesenchymal stem cells; 3, preparing an umbilical cord mesenchymal stem cell exosome; and 4, preparing the rhinitis spray. The rhinitis spray prepared by the method disclosed by the invention is simpler and more convenient to use. The exosome, the platelet growth factor and other substances in the rhinitis spray well solve the core problems of single curative effect, large side effect, low compliance and the like in the traditional rhinitis treatment, and through the induction and repair functions of the stem cell exosome and the bactericidal ability of the antibacterial peptide, the nasal cavity environment is improved, the anaphylactic reaction is reduced, the nasal mucosa is repaired, and the rhinitis treatment effect is improved. The allergic rhinitis is expected to be fundamentally treated.
Owner:山西药科职业学院

Private care wet tissue containing antibacterial composition and preparation method of private care wet tissue

The invention discloses a private care wet tissue containing a bacteriostatic composition, the private care wet tissue comprises a composite non-woven fabric base material and an impregnation liquid, the impregnation liquid comprises the bacteriostatic composition, a soothing anti-inflammatory agent, a moisturizing repairing agent, an odor removal regulator, a cosolvent and a stabilizer; the preparation method comprises the following steps: adding purified water, a citric acid-sodium citrate buffer agent and EDTA (Ethylene Diamine Tetraacetic Acid) disodium into a vacuum stirring tank, then adding glycerol, micromolecular sodium hyaluronate and ceramide 3, and then adding L-lactic acid and a lactobacillus acidophilus fermentation product; sequentially adding nisin, cranberry extract, polyhexamethylene biguanide hydrochloride and beta-cyclodextrin inclusion tea tree essential oil, and finally adding dipotassium glycyrrhizinate, allantoin and citrus extract. Different from the prior art that private care wet tissues only have a single antibacterial function and neglect flora balance, peculiar smell is covered by depending on essence, the base material and the steeping liquor are designed at the same time, and the functions of bacteriostasis and antibiosis, gentle private care, odor removal and itching relieving, inflammation prevention and swelling prevention, flora balance maintenance and the like are achieved.
Owner:MIAOWANG PHARMACEUTICAL (GUANGZHOU) CO LTD

Gelatin-bacteriocin amino acid-dialdehyde starch composite film and preparation method and application thereof

ActiveCN119707738Bdense microstructureuniform microstructureBio-packagingImino compound preparationComposite filmGlycerol
The application discloses a gelatin-bacteriocin amino acid-dialdehyde starch composite film and a preparation method and application thereof. The preparation method of the composite film comprises the following steps: adding a crosslinking agent into a gelatin solution, adding N-hydroxysuccinimide into the gelatin solution after activation for a set time, then adding bacteriocin amino acid into the gelatin solution, coupling for a set time under weak acid condition and in the dark, and obtaining Gel-MAAs; dissolving the Gel-MAAs in water to obtain a composite solution; dissolving dialdehyde starch in water, gelatinizing, adjusting to weak alkalinity, and obtaining a dialdehyde starch solution; adding the dialdehyde starch solution into the composite solution, mixing uniformly, reacting at 35-45 DEG C for 1-3 h, adding glycerol with a mass fraction of 1-5%, ultrasonic degassing, pouring the film solution into a mold, and drying, and thus the composite film is obtained. The composite film has excellent mechanical properties, physicochemical properties, ultraviolet resistance, good biocompatibility, and great potential in the field of active composite films.
Owner:SHANDONG UNIV

Lactobacillus paracasei subsp. paracasei with antibacterial and fermentation improvement properties, its bacteriocin and applications

PendingCN122344540ABiotechnologyMicroorganism
The application belongs to the technical field of microbial fermentation, and provides Lactobacillus paracasei subsp. paracasei with bacteriostatic and fermentation improvement characteristics, as well as a bacteriocin and application thereof. The classification name of the Lactobacillus paracasei subsp. paracasei is Lactobacillus paracasei subsp. paracasei, which has been preserved in the Guangdong Microbial Culture Collection Center (GDMCC) on June 25, 2025, the address of the preservation center is Building 59, 5th Floor, 100, Martyrs' Road, Guangzhou, and the preservation number is GDMCC No: 66588. The YCL29 bacteriocin produced by the application exhibits a significant inhibitory effect on Vibrio parahaemolyticus, and the starter prepared by the strain can be used to improve the flavor quality and metabolic regulation of fermented fish tea, thereby providing a new solution for developing a local starter with the functions of inhibiting raw material source pathogenic bacteria and regulating fermentation quality.
Owner:HAINAN UNIV

Bacteriophages producing heterologous bacteriocins

ActiveUS12673078B2BiotechnologyHeterologous
The present invention relates to the field of medicine, specifically the field of bacterial infection and treatment thereof.
Owner:ETH ZURICH

A ginseng fruit juice drink with high clarity and long shelf life and a preparation method thereof

The present application relates to the technical field of food chemistry processing, and discloses a ginseng fruit juice drink with high clarity and long shelf life and a preparation method thereof, wherein the preparation method comprises the following steps: subjecting fresh ginseng fruits to blanching color protection and acidification pretreatment to obtain pretreated ginseng fruit juice; subjecting free phenolic substances in the fruit juice to oxidative polymerization under the condition of continuous oxygen supply with laccase as a catalyst, removing insoluble polyphenol polymers by centrifugation to obtain depolymerized ginseng fruit juice; preparing TEMPO oxidized nanocellulose with a surface rich in carboxyl groups; adding the above nanocellulose dispersion, honey and streptococcal bacteriocin into the depolymerized fruit juice, and performing membrane filtration to obtain stabilized ginseng fruit juice; performing pasteurization, filling into a packaging container with a composite oxygen barrier inner liner of sodium alginate and beeswax, and cold storage aging to obtain a finished product.

Plant-derived natural preservative compound as well as preparation method and application thereof

The invention provides a plant source anti-corrosion compound as well as a preparation method and application of the plant source anti-corrosion compound. The feed additive is prepared from the following components in parts by weight: 3 to 5 parts of clove extract, 3 to 5 parts of rosemary extract, 2 to 4 parts of star anise extract, 0.2 to 0.5 part of nisin, 0.1 to 0.3 part of natamycin, 0.1 to 0.5 part of epsilon-polylysine, 0.1 to 0.5 part of vitamin E, 0.1 to 0.5 part of sodium alginate, 1 to 2 parts of chitosan, 5 to 10 parts of maltodextrin and 2 to 4 parts of starch octenyl succinate. The double-wall material microencapsulated plant source preservative compound disclosed by the invention is used as a preservative, under the addition amount of 0.3 wt%, the normal-temperature shelf life of baked food can be prolonged from 3 days to 9-12 days, and the inhibition rate for aspergillus niger, aspergillus flavus, saccharomyces cerevisiae and bacillus subtilis is gt; the quality and the flavor are not influenced; the three major pain points of thermal stability, flavor compatibility and antibacterial broad spectrum are synchronously solved; the process is simple and wide in application prospect.
Owner:HENAN JULONG ENVIRONMENTAL PROTECTION TECH CO LTD