27 results about "Antimicrobial surface" patented technology

The invention relates to a preparation method of an antibacterial surface-modified polyurethane foam dressing, which comprises the following steps: firstly, preparing a polyurethane foam base material with an open pore structure through a reaction of polyol and isocyanate; then, the foam surface is subjected to plasma treatment or chemical oxidation and other pretreatment modes to activate the surface; then, grafting silane or macromolecular chain segments containing antibacterial groups on the surface of the foam; antibacterial agents such as nano-silver, quaternary ammonium salt or chitosan are further loaded; and finally, washing and drying to obtain the finished dressing. The method is simple and convenient to operate, the antibacterial property of the polyurethane foam can be effectively improved, the good liquid absorption property and softness of the polyurethane foam are kept, and the method is suitable for preparing dressings for chronic wounds, surgical postoperative wounds and infectious wounds.

This invention discloses a polymer-loaded drug-eluting nanoparticle with high encapsulation efficiency and its application in coatings and surface film materials. The polymer-loaded drug-eluting nanoparticles are prepared via emulsion polymerization, simultaneously loading antibacterial drugs with different log P values. The preparation process is simple, and the resulting product has small particle size, high molecular weight, high uniformity, and high drug encapsulation efficiency, achieving the substitution of non-reactive surfactants with reactive surfactants. A coating can be prepared using the above-mentioned polymer-loaded drug-eluting nanoparticles. The coating can be further used to prepare sustained-release antibacterial surface film materials through cross-linking film formation, exhibiting good mechanical properties, excellent chemical resistance, and high safety. This invention can be widely applied to various environmental and material surfaces, including but not limited to surface modification of instruments and building materials in residential and medical environments, thereby achieving a long-lasting antibacterial effect.

Despite the existence and deployment of a range of antimicrobial / disinfectant / sterilization technologies and products, transmission of infectious diseases remains a significant problem worldwide, continuing to cause hundreds of millions of infections and millions of deaths every year of both human beings and animals. State-of-the-art technologies suffer from several disadvantages including being discrete in space and time, being overly dependent on human skill and discipline, and in some cases having harmful side-effects to human health. This invention proposes a series of industrial grade antimicrobial product designs, and materials and methods to make them highly effective products that offer continuous antimicrobial action, with minimum dependence on human discipline and skill once deployed, and with no harmful side-effects. Methods may include either or both first and second materials be formed by vapor or solution-based coating schemes and many may be antimicrobial in nature. Nanopores and / or nanotubes produce an ultra-high anti-microbially active surface area.

Despite the existence and deployment of a range of antimicrobial / disinfectant / sterilization technologies and products, transmission of infectious diseases remains a significant problem worldwide, continuing to cause hundreds of millions of infections and millions of deaths every year of both human beings and animals. A field-deployable antimicrobial surface product assembly designed for gases or liquids including: a substrate configured as a tile or a mesh: an adhesion layer disposed on at least one surface of the substrate: a first material in contact with at least one surface of the adhesion layer, where the first material includes nanotubes and / or nanopores, where the nanotubes and / or nanopores are open on one end only; and a second material deposited on at least a majority of surfaces of the nanotubes and / or nanopores which includes at least one antimicrobial material, and where the second material inactivates biological microorganisms in gases and liquids upon physical contact.

The present invention is directed to an antimicrobial substrate having a layer of PbTe quantum dots (QD) attached to an outer surface of the material. Further provided is a method of fabrication the substrate / modification of a material for obtaining an antimicrobial surface.

The application discloses a cassava tuber postharvest browning inhibition and fresh storage quality preservation treatment method, which comprises a three-step synergistic process of polyphenol oxidase targeted inhibition pretreatment, selective air permeable composite coating treatment and biological antagonistic bacteria surface inoculation treatment. First, the tuber is immersed in a vacuum infiltration treatment of a citric acid and L-cysteine hydrochloride composite inhibition solution, then is immersed and coated with a chitosan-sodium alginate-nano silicon dioxide selective air permeable composite coating, and finally is sprayed with bacillus subtilis inoculation. The three-step treatment synergistically realizes vascular browning inhibition for 25-30 days, and prolongs the shelf life from 2-3 days to 3-4 weeks.

The invention discloses a laser-induced periodic structure and chemical composite coating synergetic antibacterial surface and a preparation method thereof. A periodic surface structure LIPSS is etched on the surface of a base material through laser treatment, the structure period is controlled to be about 350 nm, the surface subjected to laser treatment is combined with a composite chemical coating (PCA) through chemical plating, and polydopamine PDA serving as a strong adhesive can be combined with non-toxic natural polymer chitosan CS; meanwhile, silver ions Ag < + > are reduced into silver nanoparticles (AgNPs) by utilizing the reduction characteristic of PDA, PDA-CS-Ag is co-deposited on the LIPSS through chemical plating, the modified Ti-PCA-LIPSS modified surface is obtained, and the modified surface can remarkably inhibit biological film formation and reduce bacterial adhesiveness. The modification method can be applied to the field of material surfaces, and particularly has potential application prospects in modification of medical implant materials.

The present invention relates to nuclease bacteriocin-derived antimicrobial protein complexes, their preparation and use, and related products having antimicrobial surfaces. The complexes comprise a nuclease bacteriocin polypeptide and an immunity polypeptide linked to a bacteria-binding moiety.

The present invention relates to a cell culture vessel characterized in that it comprises an inner surface on which one or more lectins are immobilized, the lectins being capable of binding to one or more species of microorganisms. Furthermore, the invention relates to a method for cultivating cells, comprising bringing the cell culture medium containing the cells into contact with a surface bearing immobilized lectin, and to the use of immobilized lectin to reduce microbial contamination in a cell culture brought into contact with such a surface.

Community-associated and hospital acquired infections caused by bacteria and viruses on surfaces are global challenges to human health. New strategies that offer non-specific and broad protection are urgently needed. Irradiated cerium nanoparticles IrCNPs are provided which optionally are synthesized with a metal such as silver. These nanoparticles are designed to have superior function due to a higher trivalent (Ce3+) surface fraction, which produces high potency and residual effects on a variety of surfaces. Preferred IrCNPs can rapidly and completely eradiate Pseudomonas aeruginosa, Staphylococcus aureus, and methicillin resistant S. aureus, both species and biofilm, within 3 hours of exposure, and are effective against viruses as well.

Surface treatment powders including a peroxide source active, an anionic surfactant adjuvant, and an alkaline salt arc disclosed. The surface treatment powders are substantially free of quaternary ammonium compounds and bleach activators. The surface treatment powders exhibit biocidal activity under EN 1276 and fungicidal activity under modified EN 1650 or modified EN 13697. Methods of making and using the surface treatment powders are further disclosed.

A method for handling of a surgical instrument in a healthcare facility during a reprocessing cycle. The method including: reprocessing the surgical instrument in at least one reprocessing apparatus for cleaning the surgical instrument, transporting the cleaned surgical instrument from the at least one reprocessing apparatus to a storage cabinet with a transport container comprising at least one first wall having a first inner surface defining a first storage space for accommodating the surgical instrument, and storing the transported surgical instrument in a storage cabinet comprising at least one second wall having a second inner surface defining a second storage space for accommodating the surgical instrument. Wherein at least a portion of the first inner surface and second inner surface of the storage cabinet and the transport container is an antimicrobial surface.

A multi-layered polymeric checkstand conveyor belt of the type used in grocery stores that is printed to display advertising information to engage the shopper at the point of sale and coated with a durable and impervious antimicrobial-containing surface coating. The inclusion of a QR code on the printed belt enables a shopper to easily access the information with a QR code reader app on the shopper's cell phone which directs to the store's website. The advertising and information content on the website can be easily changed and updated by the store so that the information content, including store promotions and special events are kept current. The antimicrobial agent in the surface coating is a quaternary ammonium organosilane compound that kills microbes on contact and has long-lasting residual effects to destroy and prevent the proliferation of microbes such as bacteria, viruses, mold, and the like. However, the cleanliness of the antimicrobial checkstand conveyor belt must be maintained by regular, and preferably at least daily, cleaning with an all-purpose cleaner and application of an antimicrobial surface protectant that inhibits the growth of bacteria the conveyor belt surface for an extended period of time. Compliance with the cleaning procedure is facilitated and ensured by the provision of an App downloaded to a tablet PC, for example, that has a detailed dashboard and accessible data to remind, report, and confirm cleaning of the belt.

The present invention discloses a method for preparing a touch screen and a touch screen structure, wherein the preparation method comprises: performing an optimization treatment on a tin surface of a cover glass to remove residual impurities and defects on the glass surface and forming a plurality of fine pits evenly distributed on the tin surface; performing an antibacterial treatment on the cover glass to form an antibacterial surface with silver ions on the cover glass; covering the processed tin surface with a bonding layer so that the optical resin material of the bonding layer is filled into the fine pits on the tin surface, and the relative refractive index between the bonding layer and the cover glass is between 1.04 and 0.96; and providing a touch sensor, and sequentially and closely overlapping the cover glass, the bonding layer and the touch sensor to form a touch screen structure with high light transmittance and antibacterial effect.

The present disclosure relates to a composition and a method of making microgel particles with antimicrobial properties, for example, for packaging, food, textiles, and medical applications. In an implementation, an antimicrobial microgel comprises: a first peptide comprising arginine, the first peptide in a concentration of about 0.1 mg / mL to about 20 mg / mL; an organic acid in a concentration of about 0.6mg / mL to about 20 mg / mL, and a second peptide comprising at least one amine group, the second peptide in a concentration of about 0.4 mg / mL to about 8 mg / mL, and a method of making the same. These particles may be used as a stand-alone antimicrobial in liquid or as a coating on surfaces. The antimicrobial microgel may be used to provide antimicrobial food packaging including a non-migrating antimicrobial surface for controlled and sustained protection against spoilage or pathogenic organisms without compromising the integrity or flavor of the packaged food.

The invention discloses a long-acting antibacterial surface modified titanium metal material as well as a preparation method and application thereof. The titanium dioxide nanotube array titanium is constructed on the surface of the titanium implant, and the PLGA coating with the optimized layer number is deposited, so that precise slow-release drug loading of the antibacterial polypeptide is realized. The coating not only overcomes the defects of uncontrollable initial release and limited lasting time of a traditional single-layer coating, but also remarkably prolongs the antibacterial validity period, can provide stable antibacterial protection as long as several days for the surrounding environment of a postoperative implant, and reduces the infection incidence rate.

An antimicrobial composition is provided. The antimicrobial composition includes a polymer matrix, an oil-derived component covalently bonded to the polymer matrix, and an oil-derived antimicrobial component non-covalently associated with at least one of the polymer matrix and the oil-derived component. Methods of making and using the antimicrobial composition are also provided.

The present disclosure relates to a composition and a method of making microgel particles with antimicrobial properties, for example, for packaging, food, textiles, and medical applications. In an implementation, an antimicrobial microgel comprises: a first peptide comprising arginine, the first peptide in a concentration of about 0.1 mg / mL to about 20 mg / mL; an organic acid in a concentration of about 0.6mg / mL to about 20 mg / mL, and a second peptide comprising at least one amine group, the second peptide in a concentration of about 0.4 mg / mL to about 8 mg / mL, and a method of making the same. These particles may be used as a stand-alone antimicrobial in liquid or as a coating on surfaces. The antimicrobial microgel may be used to provide antimicrobial food packaging including a non-migrating antimicrobial surface for controlled and sustained protection against spoilage or pathogenic organisms without compromising the integrity or flavor of the packaged food.

An arrangement of a lens less imaging microscopy system having an antimicrobial and anti-bacterial surface. The system provides a modular layout, i.e., having exchangeable or interchangeable modules along with autoclave ability of individual modules. The lens less imaging system may include a light engine module, sample containing specific module, camera module, chip dock module that are swappable, respectively. The lens less imaging system may also include a software module that allows recognition of attachments and detachments of the various modules. The lens less imaging system has higher flexibility and affordability due to the swappable modules.

The disclosure relates to anti-bacterial thin films for surfaces. Specifically, the disclosure relates to photocatalytic, superhydrophobic thin films for prevention of certain infectious ambulatory diseases, as well as systems and methods for their formation.

A method of manufacturing a metal component with an anti-microbial molecular layer may comprise: disposing the metal component in a piranha solution; washing the metal component; and grafting a surface of the metal component with a Si-Quat or hybrid Si-Quat molecular layer.

The present disclosure concerns copper coatings on glass with a thickness of about 8 to 10 nm to maintain high levels of transparency. In some aspects, the coatings are of copper, copper (I) oxide, and / or copper (II) oxide. In some aspects, the copper coatings as set forth herein provide an antiviral and / or antimicrobial surface for safer touch-screen devices.

Polycationic polymeric antimicrobial surfactant and polymeric biocompatible antimicrobial surfactant compositions are useful in dispersing various compounds in a carrier liquid. The polycationic polymeric antimicrobial surfactant and polymeric biocompatible antimicrobial surfactant compositions employ polymers having both hydrophilic domains and hydrophobic domains so that the compositions can disperse particles such as polymer particles or droplets in a continuous phase as well as provide stable dispersions that have not been provided before. The antimicrobial properties of the compositions provide much-needed capabilities of fighting infectious agents such as bacteria and viruses in a wide spectrum of products such as paint, adhesives, and coatings. Methods of using these compositions as well as methods of making products using the compositions are disclosed.

A method includes depositing an antimicrobial material onto a surface of a substrate. The method includes binding a photochromic material to the antimicrobial material. Depositing the antimicrobial material and binding the photochromic material can include forming a mixture of the antimicrobial material and the photochromic material and depositing the mixture onto the surface of the substrate. It is also contemplated that depositing the antimicrobial material and binding the photochromic material can include first depositing the antimicrobial material onto the surface of the substrate and then depositing the photochromic material onto the antimicrobial material.

Disclosed are methods for detecting an antimicrobial surface coating on a substrate including the steps of applying an anionic agent to a surface of the substrate, allowing the anionic agent to bond to antimicrobial surface coating present on the substrate, removing unbonded anionic agent, subjecting the surface of the substrate to a predetermined process to effect a change in the bonded anionic agent, observing the change, and verifying, based on the observed change, the presence of antimicrobial surface coating on the substrate. Further disclosed are antimicrobial surface coating solutions, methods for their application, and methods for reactivated antimicrobial surface coatings.

A phase stable, concentrated antimicrobial solution having a pH less than 0.6, comprising:a. an effective amount of at least one sparingly soluble antimicrobial agent;b. an effective amount of at least one antimicrobial surfactant selected from the group consisting of anionic surfactants and amphoteric surfactants; andc. an effective amount of at least one solvent selected from the group consisting of esteramides, diamides, branched dibasic esters, and alkyl pyrrolidones;wherein, the weight ratio of the at least one antimicrobial surfactant to the at least one solvent is from about 1:3 to about 3:1, and wherein the solution, when diluted with an aqueous diluent at a ratio of from about 1:64 to about 1:1024 has a pH of from about 1 to about 6, and passes the Germicidal Spray Testing AOAC 961.02 test method, at room temperature, and at a contact time of no greater than 10 minutes against S. aureus. Effective ready-to-use (RTU) solutions, kits for use in making the concentrated and RTU solutions, methods of antimicrobial reduction using the solutions, and methods of making the solutions are also disclosed.

The present development is an antimicrobial surface nanostructured carbon-based coating for a substrate, a process for making the antimicrobial surface coating, and a method for using the coating to inhibit pathogen growth on the substrate surface. The carbon-based coating material comprises pure carbon deposited on the substrate as a plurality of elongated nanostructures wherein each nanostructure has a high aspect ratio. The high aspect ratio creates needle-like nanostructures on the surface that exhibit antimicrobial properties. In an exemplary embodiment, the carbon-based coating is a diamond coating wherein the elongated nanostructures have a needle-like morphology and each needle has a height of <5 μm and an extremely sharp radius of curvature at the tip.