120 results about "Polymer brush" patented technology

The invention discloses a preparation method of Fe3O4 magnetic nanoparticles rich in carboxyl groups on the surface, which comprises the following steps: modifying Fe3O4 nanoparticles by using polyethylene glycol and silicon dioxide to enhance the dispersity and biocompatibility of the magnetic nanoparticles, modifying the surfaces of PEG-Fe3O4 coated SiO2 nanoparticles by using a silane coupling agent containing silane groups and unsaturated double bonds to obtain the magnetic nanoparticles rich in carboxyl groups on the surface, and modifying the magnetic nanoparticles rich in carboxyl groups on the surface by using a silane coupling agent containing silane groups and unsaturated double bonds to obtain the magnetic nanoparticles rich in carboxyl groups on the surface. Then octavinyl-POSS and double bonds on the surfaces of the nano particles are subjected to click modification to form an octahedral cage, 4-mercaptobenzoic acid and double bonds are further subjected to click modification, the surfaces of the nano particles are rich in carboxyl, and a polymer brush rich in carboxyl is constructed. Compared with a conventional streptavidin coupling method, a high-density polymer chain provides a large number of carboxyl active binding sites, so that the streptavidin coupling amount is increased, the antibody coupling rate is increased, and a solution is provided for applications such as high-sensitivity biological detection, efficient targeted drug delivery and stable immunoassay.

The application belongs to the technical field of membrane separation materials, and discloses an ultrahydrophilic oil-water separation membrane, a preparation method and application thereof, and comprises the following steps: 2-(2-bromoisobutyryloxy)ethyl methacrylate monomers are prepared from 2-hydroxyethyl methacrylate and 2-bromoisobutyryl bromide, and a polymer with an atom transfer radical polymerization initiator is prepared through a free radical polymerization reaction; the polymer with the atom transfer radical polymerization initiator and polyacrylonitrile are dissolved into a solvent, and a PAN / P(AN-g-BIEM) blended membrane is prepared through a non-solvent induced phase separation method; and a hydrophilic polymer brush is grafted to the surface of the PAN / P(AN-g-BIEM) blended membrane to obtain the ultrahydrophilic oil-water separation membrane; the ultrahydrophilic oil-water separation membrane prepared by the application has a high separation flux, excellent oil-water separation efficiency and separation performance for different oil-in-water emulsions.

The invention discloses a DA bond polymer with antibacterial and self-repairing functions for a wood surface as well as a preparation method and a use method of the DA bond polymer. Chitosan serves as a wall material, cinnamon essential oil serves as a core material, the cinnamon essential oil and chitosan antibacterial microcapsules are prepared through emulsification, crosslinking and spray drying, and essential oil controlled release is achieved. Then bisphenol A diglycidyl ether DGEBA and furfuryl alcohol FA are used as raw materials, furyl functional epoxy resin FER is prepared under the catalysis of triethylamine TEA, bismaleimide BMI is added, and a DA bond self-repairing polymer is prepared through a DA reaction; and adding 4, 4-diaminodiphenylmethane DDM into the system, reacting with redundant DGEBA to generate a cross-linked polymer network, and adding the microcapsules into a DA bond semi-interpenetrating self-repairing network solution to obtain the DA bond polymer. A thin film formed by brushing and curing wood has antibacterial and self-repairing functions, scratches and microcracks on the surface of the wood can be repaired, and microbial erosion is inhibited.

The invention relates to the technical field of blood purification materials, in particular to a zirconium-titanium bimetal MOF hollow microsphere adsorbent and a preparation method and application thereof. The adsorbent is based on a Zr / Ti bimetallic node and a phosphonic acid-carboxylic acid mixed ligand, a composite MOF hollow microsphere structure with high stability and high specific surface area is constructed through a solvothermal and polymerization synergistic reaction in a water-in-oil suspension system, a phosphonic acid group and Zr are strongly coordinated to improve the stability of a framework, and the composite MOF hollow microsphere structure has a high specific surface area. The carboxylic acid group keeps the hydrophilicity of the pore channel; meanwhile, a cross-linked network of acrylamide and N, N '-methylene bisacrylamide penetrates through crystal gaps in the balling process, so that the material has excellent mechanical strength and fluid stability; and a sulphobetaine amphoteric polymer brush layer is constructed on the surface of the MOF through endogenous initiation point modification and surface in-situ controllable free radical polymerization technologies, so that protein adsorption and platelet adhesion are effectively inhibited, the blood compatibility is remarkably improved, and meanwhile, the channel accessibility is maintained to promote rapid diffusion and adsorption of bilirubin.

The invention provides a hydrophilic modified polytetrafluoroethylene oil removal film and a preparation method thereof. A modified layer of the hydrophilic modified polytetrafluoroethylene oil removal film is mainly prepared from the following raw materials in percentage by mass: 8-12 wt% of a hydrophilic vinyl monomer, 0.3-0.6 wt% of a cross-linking agent, 0.2-0.5 wt% of an initiator and the balance of a deionized water solvent. A new chemical grafting modification strategy is adopted, the surface of the PTFE membrane is activated through low-temperature plasma, co-grafting and cross-linking polymerization of a hydrophilic monomer and a cross-linking agent on the surface of the PTFE membrane are initiated, and a layer of firm hydrophilic polymer brush with a three-dimensional network structure is constructed on the surface of the membrane; a stable hydration layer is formed on a membrane-water interface, the PTFE membrane is endowed with excellent underwater super-oleophobic property, the oil-water separation efficiency, flux and anti-pollution capacity of the PTFE membrane are remarkably improved, the technological process is simple, and the product performance is stable.

The invention belongs to the technical field of lithium battery negative electrode interface modification, and discloses a multifunctional two-dimensional hybrid polymer artificial SEI membrane and a preparation method and application thereof. Comprising a compound as shown in a formula I, a polymer brush is grafted on the surface of brominated graphene oxide through atom transfer radical polymerization (ATRP), monomers of the polymer brush are carboxyl-containing monomers and fluorine-containing monomers, and the artificial SEI membrane is constructed through spin coating and membrane forming. The multifunctional artificial SEI film provided by the invention has the structural and functional characteristics of two-dimensional graphene oxide and in-situ reaction type macromolecules, the mechanical property of the film can be remarkably improved by an accumulated two-dimensional skeleton, the Young modulus can reach 3.7 GPa, the growth of lithium dendrites is inhibited, and the performance of the film is improved. Functional groups (carboxyl and fluoro) in the hybrid polymer brush and lithium metal are subjected to in-situ chemical reaction, so that the electrode interface stability and the lithium deposition uniformity are improved, and the hybrid polymer brush has wide application prospects in the field of lithium batteries.

The invention relates to the field of polymer composite materials and functional films, and provides a cast film for a lithium ion battery, which is characterized in that the cast film is of a laminated composite structure, and the laminated composite structure comprises a support layer and an interface functional layer; the supporting layer comprises polymer fibers and boron nitride nanosheets which are dispersed in a three-dimensional network of the polymer fibers in a highly oriented manner; wherein the included angle between the plane normal direction of the boron nitride nanosheet and the thickness direction of the cast film is less than 30 degrees; the interface functional layer comprises a hyperbranched polymer matrix and LLZO nanowires which are distributed in the hyperbranched polymer matrix in a gradient manner; the surface, deviating from the supporting layer, of the interface functional layer is grafted with a zwitterionic polymer brush through chemical bonding; wherein the surface density of the LLZO nanowire is gradually reduced from the surface, grafted with the zwitterionic polymer brush, of the interface functional layer to the direction of an interface combined with the supporting layer; the cast film has good electrochemical performance, interface stability and safety performance.

The application relates to the technical field of shoe sole materials, in particular to a foamed composite material and application of the foamed composite material in shoe materials, which comprises EVA resin, ethylene-propylene-diene rubber, wear-resistant particles, a filler, a foaming agent, a crosslinking agent, a lubricant and an activator; wherein the wear-resistant particles are modified porous corundum, which is obtained by in-situ ring-opening polymerization of flexible PCL chains in and outside the pores of the porous corundum after surface activation; and the flexible PCL chains further have polyethylene glycol-stearic acid polymer brushes. Compared with the prior art, the application has the beneficial effects that: the EVA provides good processability and elasticity, the ethylene-propylene-diene rubber endows the material with excellent low-temperature performance and aging resistance; the corundum core of the modified porous corundum provides a high-hardness wear-resistant framework, significantly reduces the abrasion amount in a unit volume, the polycaprolactone main chain and the polyethylene glycol-stearic acid side chain compensate the rigidity of the corundum, and guarantee the high resilience, especially the low-temperature resilience, of the EVA material.

The invention discloses a medicinal glass bottle and a forming process thereof, and belongs to the technical field of medical materials, the medicinal glass bottle comprises a glass bottle body and a composite coating on the inner wall of the glass bottle; the forming process comprises the following steps: 1) pretreating the glass substrate; 2) constructing a composite layer; 3) constructing a barrier layer; and 4) cross-linking inerting and post-processing. According to the inner wall coating designed by the invention, a sandwich structure is adopted, and strong adhesive force of a bottom layer is realized through amino silane; the silver nanoparticles are anchored in situ by using a branched polyethyleneimine network, so that stable antibiosis is realized; a compact zwitterionic polymer brush is constructed on the outermost layer through surface-initiated polymerization, and a super-hydrophilic and biologically inert surface is provided; and finally, through cross-linking inerting treatment, the stability and safety of the coating are greatly improved. The problems of medicine adsorption, microorganism breeding, coating instability and the like of a traditional packaging material are solved, and a safe and reliable novel solution is provided for medicine packaging.

This application discloses a nanovesicle, its preparation method, and its application. The nanovesicle includes a core layer containing hemostatic active ingredients; first, second, third, and fourth intermediate layers (collectively forming a shell); and an outer layer (corona). The first intermediate layer is composed of a pH-sensitive polymer material, sensitive to the absolute value of transmembrane pH difference; the second intermediate layer is composed of a hypoxia-sensitive lipid complex; the third intermediate layer is composed of an osmotic pressure-sensitive phospholipid bilayer, sensitive to the absolute value of transmembrane osmotic pressure difference; the fourth intermediate layer is composed of an inflammatory factor / reactive oxygen species-sensitive hydrogel; and the outer layer is composed of a bifunctional polymer brush possessing both temperature difference response and mechanical difference sensing capabilities. This nanovesicle can respond to multidimensional microenvironmental differences between the intravascular and extravascular sides at the bleeding point, orderly disintegrating and releasing hemostatic active ingredients, providing a feasible technical approach for developing precise hemostasis strategies that do not rely on activation of the systemic coagulation system.

Disclosed herein are microfluidic assay devices that have improved versatility and reliability. An example microfluidic assay device includes a cassette having a body formed by a plurality of layers. The body includes a reaction chamber having an inlet, an outlet downstream from the inlet, and a non-fouling polymer brush with a plurality of assay reagents. The reaction chamber is configured to house a fluid sample. The body also includes a seal disposed adjacent the outlet of the reaction chamber for preventing fluid flow through the outlet, and an actuator configured to break the seal upon actuation to create a fluid flow path for the fluid sample to exit from the outlet of the reaction chamber.

The invention relates to the technical field of blood purification, and particularly discloses resin for adsorbing cell factors and a preparation method of the resin. The invention relates to a resin for adsorbing cytokines, which is a composite microsphere with a core-shell structure, a core layer is a porous polystyrene-divinyl phenyl body, and a phenylboronic acid functional group is covalently bonded on the core layer; the shell layer is a zwitterionic polymer brush grafted outside the core layer through surface-initiated atom transfer radical polymerization; the preparation method comprises the following steps: synthesizing porous polystyrene-divinyl benzene microspheres, and fixing chloromethyl on the skeleton of the microspheres to obtain a macromolecular initiator; reacting the macromolecular initiator with a compound containing phenylboronic acid groups, and covalently immobilizing the phenylboronic acid groups on the microsphere matrix; the microsphere matrix and the zwitterionic monomer are subjected to surface-initiated atom transfer radical polymerization reaction, and the zwitterionic polymer brush is formed on the surface of the microsphere. The resin provided by the invention has the advantages of high selectivity, high adsorption capacity and excellent blood compatibility.

The invention relates to a high-solid-content preparation method of a cyclic polymer brush. According to the preparation method disclosed by the invention, electrostatic mediation is utilized to realize intramolecular closed loop of the linear polymer brush, so that the preparation of the annular polymer brush under high solid content is realized; the method can be applied to various monomer systems, is high in universality, simple to operate, high in solid content, high in reaction efficiency and extremely low in by-product content, can realize preparation of the cyclic polymer brush without a complicated separation process, and has extremely high industrial application prospects.

A polymer of structure (A) with two end group R3p, and R4p, and a polymer chain (R) which has either repeat units of structures (Ip) or (IIp). R3p, is either a C-1 to C-8 alkyl, a moiety of structure (IIIp), or a moiety of structure (IIIpI). R3p is a C-1 to C-8 alkyl if the repeat unit is (IIp). R3p is structure (IIIp) or structure (IIIp1) if the repeat unit has (Ip). R4p is either a terminating moiety such as H, a moiety of structure (IVp), a moiety of structure (IVp1), or a moiety of structure (IVp2). R3p and R4p cannot respectively, both simultaneously, be moieties of structure (IIIp) and (IVp), simultaneously be moieties of structure (IIIp) and (IVp1), or simultaneously be moieties of structure (IIIp) and (IVp2). The polymer of structure (A) must contain, one grafting end group moiety selected from structures (IIIp), (IVp), (IVp1) or (IVp2). Composition of this with a solvent are used in DSA processing.

A random terpolymer of N-(2-hydroxypropyl) methacrylamide, carboxybetaine methacrylamide and sulfobetaine methacrylamide, and a polymer brush and to a functionalized polymer brush containing this terpolymer are disclosed. The random terpolymer increases the resistance of the substrate surface to non-specific adsorption of substances from biological media and / or to non-specific interaction with biological media components, and is suitable for use in the form of a polymer brush, for example in sensors or membranes.

The present application relates to the preparation field of organic polymer monolithic column, in particular to a kind of double-continuous supermacroporous cellulose / polystyrene composite monolithic column and its preparation method and application.Firstly, O / W Pickering emulsion is prepared using modified cellulose nanocrystal (CNC), and Janus CNC-PS with single side grafted polystyrene (PS) polymer brush is prepared by electron activation regeneration-atom transfer radical polymerization (AGET-ATRP) reaction system, and double-continuous phase emulsion gel (Bijel) is prepared by one-step stirring method using Janus CNC-PS with different HLB values as stabilizer.Then, double-continuous supermacroporous cellulose / polystyrene composite monolithic column is obtained by in-situ active polymerization through AGET-ATRP reaction using Janus CNC-PS as macromolecular initiator and Bijel as emulsion template.The obtained monolithic column has uniform skeleton structure, double-continuous skeleton and pore, high mechanical strength, and the unmodified side of CNC covers the outer surface of skeleton, so that the pore surface has hydrophilicity and is easy to modify.The monolithic column effectively overcomes the defects of current polymer monolithic column, such as poor biocompatibility, low mechanical strength and low specific surface area, and has great application potential in the field of enzyme and cell immobilization and biomacromolecule separation and analysis.

The invention belongs to the technical field of biomedicine, and particularly relates to a preparation method of a potassium K < + > recognition response quartz crystal microbalance chip and a blood potassium concentration quantitative detection method. A 3-aminopropyltriethoxysilane (APTES) solution is used for carrying out functionalization treatment on the surface of a silicon dioxide sheet, so that a large number of amino functional groups are obtained on the surface of the silicon dioxide sheet. The preparation method comprises the following steps: taking 4-acrylamide benzene-15-crown-5 as a template, then anchoring an ATRP (Atom Transfer Radical Polymerization) initiator-bromoisobutyryl bromide on the surface of the template through a covalent bond, and carrying out grafting construction of a benzene-15-crown-5 functional polymer brush by adopting Cu0-mediated surface-initiated atom transfer radical polymerization (Cu0-SI-ATRP) by taking 4-acrylamide benzene-15-crown-5 as a polymeric monomer. The potassium selective quartz crystal microbalance based on the crown ether functionalized polymer brush is obtained.

The invention discloses a polymer brush with a nanoscale microphase separation structure, a polymer film and a preparation method of the polymer film, the polymer brush comprises a liquid crystal unit, and the preparation method comprises the following steps: reacting the liquid crystal unit with halogenated alcohol to prepare a liquid crystal side chain; reacting the liquid crystal side chain with norbornene dianhydride to prepare a liquid crystal monomer containing carboxyl at the tail end; reacting the liquid crystal monomer containing carboxyl at the tail end with fatty alcohol or difatty glyceride to obtain a block type liquid crystal monomer; and carrying out ring-opening metathesis reaction on the block type liquid crystal monomer under the action of a Grubbs catalyst to prepare the polymer brush. The introduction of the liquid crystal unit provides stronger driving force for microphase separation of the brush polymer, so that the nanoscale microphase separation structure can be directly obtained through an annealing process under the condition of not adding any guide layer.

The invention discloses a preparation method of high-dispersity pigment carbon black, which comprises the following steps: S1, carrying out heat treatment on original carbon black under the protection of inert gas to obtain surface-activated carbon black; s2, carrying out heating reaction on the carbon black and grafting molecules to obtain functional carbon black of which the surface is grafted with specific active groups after the reaction; s3, dispersing the carbon black in an organic solvent, firstly adding an olefin pyridine monomer to carry out substitution reaction, then adding a functional monomer containing a dynamic covalent bond to carry out polymerization reaction, and forming a polymer brush on the surface of the carbon black; and S4, carrying out post-treatment to obtain the high-dispersity pigment carbon black. According to the preparation method, high steric hindrance and solvation rejection are given to the carbon black through a covalent anchoring-polymer brush structure, the sedimentation rate of an alcohol ester system is smaller than 5%, and long-term thermal aging stability is maintained by virtue of a stress relaxation mechanism of a dynamic disulfide bond; the harsh requirements of high-end printing ink, high-solid-content coatings and polymer master batches on high blackness, low sedimentation and durability can be met.

The application discloses an oily structural color pigment ink and application thereof, and belongs to the technical field of photonic crystal material preparation. Components of the oily structural color pigment ink include at least one block polymer brush, at least one resin or at least one precursor of the resin, and at least one organic solvent. The oily structural color pigment ink provided by the application is a layered structural color material obtained by self-assembly based on the microphase separation principle of the block polymer brush. The provided oily structural color pigment ink can be compatible with most common pigment coloring methods, including but not limited to screen printing, spraying, inkjet printing and intaglio printing. The structural color of the oily structural color pigment ink is not limited to the visible light band, and covers ultraviolet spectrum, visible spectrum and infrared spectrum, and the wavelength range of the covered electromagnetic spectrum is 200 nm to 2000 nm.

The invention relates to the technical field of membrane separation, and discloses a high-protein milk concentration process based on a membrane filtration technology, the process adopts an electric response membrane grafted with an electric response polymer brush on the surface, and an electric control zymogen modified by genetic engineering is added into milk feed liquid to be treated. The zymogen is modified with an electric field responsive anchoring group and an electric signal activated ferrocene protecting group. In the filtering stage, a first electric field is applied to stretch the polymer brush, so that anti-pollution filtering is realized; and in the cleaning stage, switching to a second electric field to enable the polymer brush to shrink and drive the zymogen to be anchored on the surface of the membrane, and applying an activation pulse to trigger the activity of the zymogen so as to degrade pollutants in situ. On the premise of not interrupting production, not adding chemical cleaning agents and not damaging target product protein, milk concentration is efficiently and continuously carried out, and long-term stable high permeation flux is maintained.

The invention relates to the field of cable insulating materials, in particular to a double-layer network heat-conducting composite insulating material for cables and a preparation method thereof.The material comprises an inner heat-conducting layer, a transition layer and an outer insulating layer, and in the inner layer, a three-dimensional heat-conducting network is built through a vertically-oriented boron nitride nanotube and reduced graphene oxide-boron nitride nanosheet heterostructure; flexible polymer brush grafted nanoparticles are introduced into the transition layer, so that thermal mismatch is relieved; and the outer layer is cooperated with GO-QDs by coating Al2O3 with a temperature response polymer, so that high-temperature interface self-enhancement and electron trap effects are realized, and the breakdown strength is greater than or equal to 45kV / mm. The material disclosed by the invention has the performance retention rate gt after being aged at 180 DEG C and 35 kV for 1000 hours; and meanwhile, the thermal resistance is reduced by more than or equal to 75%, the tensile strength is improved by more than or equal to 50%, the service life is remarkably prolonged, and the insulating material can be widely applied to insulation of electric automobiles and ultrahigh-voltage cables.

The present invention relates to a capillary core, an evaporator, a loop heat pipe, a cooling device, an electronic device, and a capillary core manufacturing method. The present invention aims to provide a capillary core, an evaporator, a loop heat pipe, a cooling device, an electronic device, and a capillary core manufacturing method that can improve the long-term stability of the hydrophilicity of the capillary core. The capillary core of the present invention is a capillary core of a porous elastomer that is permeated by a working fluid in a liquid phase, which is provided inside an evaporator that changes the working fluid in the liquid phase to a gas phase. The porous elastomer includes composite voids having communication holes at portions where a plurality of spherical voids partially overlap each other. The surface of the voids of the porous elastomer is coated with a hydrophilic polymer having a betaine group and a molecular weight of 10,000 or more of a polymer brush structure.

The present invention provides a method for thermal welding of thermoplastics using a hot plate, said method comprising the steps of: a) heating the hot plate to a temperature required for welding the thermoplastics, and bringing the thermoplastics to be welded into contact with the hot plate until the areas of the thermoplastics to be welded melt, and b) removing the thermoplastics from the hot plate, joining the areas of the thermoplastics and pressing them together to weld them, wherein the hot plate body is made of a material selected from the group of metal, metalloid, metal oxide, metalloid oxide, metal nitride, metalloid nitride, metal oxynitride, ceramic and / or glass, and the hot plate is provided with a polymer brush on one or more surfaces intended for contact with the thermoplastics. In further aspects, the invention discloses a device and a hot plate useful in the method.

This invention belongs to the field of biomedical adsorption materials technology, and discloses a blood purification adsorption catheter and its preparation method. The invention uses polydimethylsiloxane polymer as the main body, with two elliptical intersecting blades as a mixer structural unit. After curing with PDMS polymer, a catheter body with a specific mixer structure embedded in the inner wall is prepared. Subsequently, the inner wall of the catheter is modified by reversible addition-fracture transfer radical polymerization to form a polymer brush layer. By coupling nanoantibodies to the polymer brush, a catheter material with antigen adsorption function is prepared. The static mixer structure in the catheter material prepared by this invention can significantly enhance the diffusion and convection of target toxin molecules in the fluid, effectively improving the efficiency of specific adsorption of toxin molecules by the antibody-functionalized catheter inner wall, and is expected to be applied in clinical blood purification treatment for the removal of medium and large molecular toxins, including inflammatory factors.

The invention relates to the technical field of papermaking, in particular to a preparation method of ultrathin high-strength paper-based adhesive tape base paper. The preparation method comprises the following steps: mixing softwood pulp and hardwood pulp, forming base paper by adopting a double-net dehydration process, and forming a covalent cross-linked network in a paper sheet by adopting a cellulose reactive coupling agent with an o-benzoquinone structure and a multi-sulfydryl compound based on a sulfydryl-benzoquinone click chemistry and interface supramolecular assembly multi-bonding enhancement system; meanwhile, a dual intelligent enhancement system based on a biomacromolecule self-assembly body and a dynamic metal coordination network is established, and dynamic reversible crosslinking is constructed through a polyelectrolyte compound and a Fe < 3 + >-tannic acid coordination network; a multifunctional surface treatment technology combining a zwitterionic polymer brush and bionic in-situ mineralization is developed, a sulphobetaine methacrylate polymer brush grows through a surface-initiated atom transfer radical polymerization method, amorphous silicon dioxide is induced to be mineralized, and the adhesive tape body paper prepared through the method is high in strength.

The present application relates to the technical field of surface modification, and provides a mixed polymer brush coating resistant to wear in dry / wet environment and a preparation method thereof.The present application first prepares a silica sol-initiator coating on the surface of a substrate;then grafts self-lubricating hydrophobic polymer brushes under UV irradiation;finally grafts hydrophilic polymer brushes on the surface of the coating through ATRP reaction, so as to realize the preparation of the mixed polymer brush coating.The present application makes the mixed polymer brush coating have stronger bonding strength and wear resistance through the interaction between the initiator layer and the polymer brush layer;in water, the hydrophilic polymer brushes in the coating are combined with water molecules to swell and form an effective hydration layer, thereby playing a hydration lubrication function;in the dry state, the hydrophilic polymer brushes shrink after dehydration, so that the hydrophobic silicone brushes are exposed, thereby endowing the surface with a dry-state self-lubrication function.The method provided by the present application can be carried out under air condition, does not need a deoxygenation step, is simple to operate and easy to realize batch preparation.

The invention discloses a method for immobilizing cellulase by using a Ti3O5-based composite photothermal conversion material and application. The material is composed of a Ti3O5 core coated with polydopamine and a glycidyl methacrylate modified azobenzene polymer brush grafted on the surface of the Ti3O5 core. The preparation method comprises the following steps: forming a PDA layer on the surface of Ti3O5 through dopamine auto-polymerization, synthesizing a gAZO polymer brush, and finally modifying the gAZO onto the PDA-coated Ti3O5 through photo-initiation grafting reaction. The material disclosed by the invention can realize local temperature regulation and control at 35-50 DEG C under the irradiation of visible light of 100-150 mW / cm; when being used for immobilizing cellulase, the immobilized cellulase can be locally heated through illumination in the synchronous saccharification and fermentation process, so that the problem that the optimal saccharification and fermentation temperatures are not matched is solved, and the SSF efficiency is improved; the process is simple, and a novel controllable temperature control strategy is provided for the bio-refinery process.

The invention discloses a medical radionuclide labeled microsphere, a preparation method thereof and application of the medical radionuclide labeled microsphere in synthesis and labeling of irradiation treatment drugs in various radionuclides. The medical radionuclide-labeled microspheres are solid microspheres or hollow microspheres with the radioactive specific activity of 1.85-185 MBq / mg formed by sequentially wrapping resin microspheres with the particle size of 100-200 nm or 1-100 [mu] m, an anchoring layer with the thickness of 0.1 nm and a polymer brush with the thickness of 20-100 nm from inside to outside and then adsorbing radionuclides. The radionuclide-labeled microspheres are used for synthesizing and labeling medicines, and in-vitro cytotoxicity and mouse in-vivo transplanted tumor growth inhibition experiments show that the radionuclide-labeled microspheres have better internal irradiation treatment efficiency on malignant solid tumors; the biosecurity of the microsphere, the preparation convenience of the nuclide-labeled microsphere and the nuclide labeling stability are relatively high, and the application value is relatively high.

The invention relates to the technical field of optical thin films, in particular to an easy-to-peel PET (polyethylene terephthalate) base film for dry film photoresist and a preparation method of the easy-to-peel PET base film, and the easy-to-peel PET base film is prepared by putting PET master batches and multifunctional composite microspheres into a double-screw extruder according to a mass ratio of (85-95): (5-15) and carrying out melt blending, extrusion, sheet casting, two-way stretching and traction rolling. The multifunctional composite microsphere prepared by the invention has a unique three-layer structure of rigid SiO2 core / polyester compatible layer / fluorine-containing polymer brush, and the SiO2 core obviously improves the rigidity, dimensional stability and heat resistance of a base membrane; the polyester compatible layer ensures the excellent compatibility and dispersibility of the microspheres and the PET matrix, and avoids the reduction and embrittlement of the mechanical property of the film due to the addition of the inorganic filler; the polymer brush on the surface directly provides excellent stripping performance; the prepared base film is especially suitable for high-performance dry film photoresist, and has remarkable market application value.