62 results about "Nitroxide radical" patented technology

Inhibitor compositions for abating undesirable emulsion polymerization during processing of hydrocarbon stream laden with reactive vinylic monomers are provided. The polymerization inhibitor compositions include at least a first inhibitor compound having a stable nitroxide radical and a second inhibitor including phenylenediamine. Methods of inhibiting the polymerization of monomers using the compositions of the disclosure are also provided. The methods of inhibiting polymerization of monomers include a step of adding a composition of the disclosure to a process stream. The process stream includes an ethylenically unsaturated monomer that is suspended in the bulk-phase and highly polar solvents as distractive distillation solvents.

The invention provides a composite polymerization inhibitor for a vinyl acetate production process, especially a rectification process, the polymerization inhibitor comprises a component A and a component B, the component A is a nitroxide free radical compound, and the component B is styrene. The composite polymerization inhibitor provided by the invention fully utilizes the synergistic effect of the two polymerization inhibitors, overcomes the defect of short high-temperature polymerization inhibition validity period of a nitroxide free radical type polymerization inhibitor, remarkably improves the polymerization inhibition effect of the polymerization inhibitor, can effectively prevent self-polymerization of vinyl acetate in the production process of vinyl acetate, and improves the production efficiency of vinyl acetate. And the continuity of the production process is ensured.

A method of forming a high internal phase emulsion (HIPE) foam is provided. A nitroxide-containing monomer can be used in combination with other monomers that can then be used to make a high internal phase emulsion foam upon curing. The nitroxide group can subsequently be used to control the radical polymerization of many monomers, which can be grafted from the surface of the high internal phase emulsion foam. The resulting foam can be useful in performing separations of radioactive species, metals, metal ions, multi-element ions, metal complexes, halides, and organic chemical species in chemical process streams, clean-up operations, etc.

The invention discloses a preparation method and electrochemical energy storage application of nitroxide free radical molecules with double redox active centers and analogues of the nitroxide free radical molecules, and belongs to the technical field of nitroxide free radical molecules. Through structural design of molecular bridging substituent groups, groups with multiple bridging points, such as quaternary ammonium groups and acylamino groups, are introduced to the fourth site of a piperidine ring, and the connection mode of the groups is modulated, such as linear or branched, so that controllable coupling of two redox active center units is realized. Researches show that the types, the number and the connection mode of the bridging groups have important influences on the oxidation-reduction potential, the electrochemical kinetics and the cycling stability of target molecules. The invention further discloses a charge-discharge mechanism and a degradation path of double-electron nitroxide free radical electrolyte molecules, and provides a theoretical basis and a practical basis for stable implementation of a double-electron transfer process. The research provides a brand new design thought and technical support for constructing organic flow battery electrolyte molecules with high energy density and long service life, and has a wide application prospect.

A method for continuously producing oxetane methyl methacrylate by transesterification, which utilizes dibutyl tin oxide, methyl methacrylate and 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-oxyl radical to prepare a catalyst; methyl methacrylate is subjected to transesterification with 3-ethyl-3-oxetanemethanol, a polymerization inhibitor tetramethylpiperidine nitroxide phosphite triester and the catalyst to obtain a transesterification reaction liquid; the transesterification reaction liquid is subjected to vacuum rectification in a transesterification reactor, after recovering methyl methacrylate and 3-ethyl-3-oxetanemethanol, vacuum rectification is continued to obtain oxetane methyl methacrylate. The advantage is that the process is simple and reasonable, not only high in conversion rate and selectivity, but also high in purity, low in color and acid value of the obtained product, friendly to the environment and fully capable of meeting the application requirements in high-end fields.

Provided is a polarizing plate in which the decrease in transmittance in a high-temperature environment is suppressed. A polarizing plate has a polarizing element in which a dichroic dye is adsorbed and oriented in a polyvinyl alcohol-based resin layer, a first transparent protective film laminated on one face of the polarizing element, and a second transparent protective film laminated on the other face of the polarizing element, the polarizing element and the transparent protective films being bonded with a first adhesive layer formed from a first adhesive containing a first compound, the polarizing element and the second transparent protective film being bonded with a second adhesive layer formed from a second adhesive containing a second compound, the first compound being at least one selected from the group consisting of urea, a urea derivative, thiourea, and a thiourea derivative, and the second compound being a compound having a nitroxyl radical or a nitroxide radical.

The invention belongs to the technical field of synthesis of medicines and spices, and particularly relates to a synthesis method of trans-2-octenal. The synthesis method comprises the following steps: carrying out isomerization reaction on 1-octylene-3-alcohol under the catalytic action of 3, 4-dinitrobenzoic acid to obtain a trans-2-octylene-1-alcohol intermediate; the preparation method comprises the following steps: preparing trans-2-octenal from trans-2-octylene-1-alcohol under the oxidation action of m-chloroiodobenzene, 4-hydroxy-TEMPO (4-hydroxy-2, 2, 6, 6-tetramethylpiperidine nitroxide free radical) and peracetic acid, and further preparing the trans-2-octenal from the trans-2-octylene-1-alcohol. The preparation method is mild in reaction condition, simple to operate and free of expensive reagents or catalysts.

The invention discloses a cyclic nitroxide free radical positive electrode electrolyte and a neutral aqueous organic flow battery, and belongs to the technical field of organic flow batteries. According to the positive electrode electrolyte, halide ions (such as chloride ions) in an existing supporting electrolyte are replaced by inorganic salt composed of anions such as sulfate ions and bis (trifluoromethanesulfonyl) imine ions, and the precipitation side reaction caused by the chloride ions in the charging and discharging process is avoided. Sulfate and bis (trifluoromethanesulfonyl) imine salt have wider electrochemical stability windows, and anions of the sulfate and bis (trifluoromethanesulfonyl) imine salt have a regulation effect on a free water structure, so that a more stable solvated water environment is favorably formed, strong solvating behaviors of H < + > and OH <-> are reduced, a decomposition reaction of water in the electrolyte is inhibited, and the tolerance of a system to pH fluctuation is improved; the working potential window of the electrolyte is widened, and the operation stability and the electrochemical performance of the flow battery under the neutral or near-neutral condition are improved. According to the scheme, a new material design thought and an application basis are provided for constructing a high-stability and high-safety aqueous organic flow battery.

The use of a cell-permeant molecular probe to assay the presence, and monitor the production, of the reactive oxygen species, superoxide, in red blood cells (RBCs) is described. The assay is performed using electron paramagnetic resonance (EPR) spectroscopy and a cell-permeant hydroxylamine spin trap. The cell-permeant molecular probe is not detected or quantifiable by EPR in its reduced form. However, upon entering the RBCs, the probe is oxidized by reacting with superoxide to yield a stable nitroxide radical that is detected and quantified using EPR. Our studies indicate that superoxide production is consistent with RBC metabolism that predicts lipid oxidation, membrane injury and poor post-transfusion performance. Therefore, measurement of reactive oxygen species can be used as an indicator of RBC quality at the time of donation and after storage.

The invention discloses a polymerization inhibitor for rectification of carboxylic acid vinyl ester. The polymerization inhibitor is a composite polymerization inhibitor composed of a polyphenol polymerization inhibitor, a nitroxide free radical compound and an arylamine polymerization inhibitor. The composite polymerization inhibitor prepared by the invention has good solubility in a carboxylic acid vinyl ester system; the polymerization inhibition efficiency in the induction period is high, and meanwhile, the induction period is prolonged, that is, the polymerization inhibition lasting validity period of the polymerization inhibitor in a carboxylic acid vinyl ester rectification process is long.

The present invention belongs to the technical field of organic chemical synthesis, and specifically relates to a rhein nitroxide derivative, a synthesis method, and an application thereof. The present invention uses rhein, an antioxidant pharmacological substance from the traditional Chinese medicine rhubarb, as a research object, selects its carboxyl group at position 3 as a modification site, and introduces four active intermediate nitroxides into the rhein structure based on the amide condensation and esterification reaction mechanisms and the pharmacophore splicing principle. Thirty rhein nitroxide derivatives were designed and synthesized, thereby establishing a method for synthesizing novel rhein nitroxide derivatives with mild reaction conditions, environmental friendliness, and high yield. The provided novel rhein nitroxide derivatives have the ability to scavenge DPPH and ABTS free radicals, have a protective effect on oxidatively damaged cells, and have the ability to delay the lifespan of Caenorhabditis elegans. Their effects are superior to those of rhein, providing a new approach for the development of antioxidant and anti-aging drugs.

The invention discloses a method for preparing 2, 5-furandicarboxylic acid under mild conditions, which comprises the following steps: in a water phase system, by taking bifunctional furan aldol as a raw material, a nitroxide free radical compound and nitrate as catalysts and bromine-containing inorganic salt as a promoter, oxidizing the bifunctional furan aldol under the action of an oxidizing agent to obtain the 2, 5-furandicarboxylic acid. And 2, 5-furandicarboxylic acid is obtained. The method is mild in reaction condition, can realize high conversion rate and high yield at room temperature, and has the advantages of low energy consumption and safe process; the used solvent is a water phase, no organic solvent is needed, and the method has the advantages of being green, environmentally friendly, low in price, high in safety, non-toxic and the like. The method avoids the adverse factors of organic solvent and high temperature in the conventional oxidation preparation process of the FDCA, and is a new process for preparing the FDCA.

This invention relates to a high-efficiency outdoor flame retardant additive, its preparation method, and its application, belonging to the field of polymer material additives technology. This high-efficiency flame retardant additive has N,N'-di(3-aminopropyl)-1,2-ethylenediamine as its main chain, linked with dialkoxy-monochlorotriazine, containing six N-cyclohexyloxy hindered amine groups, with a purity ≥99.5% and a total yield ≥80%. It is prepared from 2,2,6,6-tetramethylpiperidone nitroxide radical, cyclohexane, etc., via N-cyclohexyloxylation, reductive amination, N-acylation, and nucleophilic substitution reactions. Adding 0.5~3.0 wt% of this stabilizer to polypropylene materials can impart UL-94 VTM-0 flame retardancy and excellent photothermal stability. Furthermore, the preparation process is low-cost and environmentally friendly, solving the technical problems of easy deactivation of hindered amines, functional separation of additives, and low yield in traditional synthesis processes. It is suitable for polypropylene fibers, films, nonwoven fabrics, and other polyolefin products.

The invention belongs to the technical field of binders, and particularly relates to a composite binder, the composite binder comprises a block copolymer and polyvinylidene fluoride, the block copolymer comprises a first block and a second block, the first block is a prepolymer of 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine nitroxide free radicals and polyethylene oxide, the second block is a prepolymer of 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine nitroxide free radicals and polyethylene oxide, and the third block is a prepolymer of 4-hydroxy-2, 2, 6, 6-tetramethylpiperidine nitroxide free radicals and polyethylene oxide. And the second block is polystyrene. According to the composite binder, the solubility of the block copolymer in an electrolyte is controlled by regulating and controlling the molecular weight of the block copolymer and the polystyrene, the binding power of an active substance and a pole piece is improved in a working temperature interval, the block copolymer only swells to a certain degree in the temperature interval and cannot be dissolved, and the liquid retention performance of a battery cell can be improved. And when the internal heat accumulation temperature of the battery cell abnormally rises and exceeds the dissolvable temperature of the block copolymer, the block copolymer can be gradually dissolved in the electrolyte, so that the viscosity of the electrolyte is increased and gelatinized, the reaction degree of the electrolyte is reduced, and the risk of thermal runaway is prevented.

The invention discloses a preparation method of sulfoalkyl (methyl) acrylate, which is characterized in that (methyl) acrylic acid and hydroxyalkyl sulfonic acid are used as raw materials, an acidic resin catalyst is adopted, and the sulfoalkyl (methyl) acrylate is prepared by reaction in the presence of a solvent and a compound polymerization inhibitor, the compound polymerization inhibitor is a combination of a phenolic compound and at least one of the following compounds (A)-(D): (A) a quinone compound; (B) a nitroxide radical compound; (C) an inorganic salt compound; and (D) copper N, N-di-n-butyl dithiocarbamate. By using the method, the polymerization side reaction in the reaction process can be effectively inhibited, and the method has the advantages of short reaction time, simple post-treatment and low content of the hydroxyalkyl sulfonic acid dimer in the product.

This invention discloses a fluoropiperidine nitroxide radical derivative, a positive electrode electrolyte containing the same, and its applications. The fluoropiperidine nitroxide radical derivative is a compound represented by Formula I. The piperidine nitroxide radical derivative of this invention exhibits high stability and high solubility as a positive electrode active material in organic flow batteries, showing promising application prospects.

Provided are: a method for producing a resin, the method having (i) a step for polymerizing raw material monomers including specific monomers described in the description, in the presence of a nitroxide radical or a dithioester-based compound, wherein in step (i), a reaction solution containing a solvent, an initiator at a quantity of 80 mass% or more of the total initiator amount and a nitroxide radical or a dithioester-based compound at a quantity of 90 mass% or more of the total nitroxide radical or dithioester-based compound amount is charged in a reaction vessel, and at least some of the raw material monomers are added dropwise to the reaction solution at a temperature that is not lower than the decomposition temperature of the initiator; a method for producing an active light ray-sensitive or radiation-sensitive resin composition, which includes the method for producing a resin; an active light ray-sensitive or radiation-sensitive resin composition; an active light ray-sensitive or radiation-sensitive resin film obtained using the active light ray-sensitive or radiation-sensitive resin composition; a pattern formation method; and a method for manufacturing an electronic device.

This application provides a semiconductive shielding material, its preparation method and application, and cables, belonging to the field of cable material technology. The semiconductive shielding material comprises the following components in parts by weight: 50-65 parts matrix resin, 25-35 parts conductive carbon black, 5-10 parts acrylate-terminated polyalphaolefin, 1-3 parts antioxidant, 1-2 parts dispersant, 0.1-1 parts thermally triggered free radical stabilizer, and 0.5-2 parts crosslinking agent; wherein the thermally triggered free radical stabilizer includes nitroxide free radical compounds. The combined use of these components significantly improves the scorching resistance, crosslinking density, and mechanical properties of the semiconductive shielding material, exhibits excellent processability, and significantly enhances the safety and service life of cables. The introduction of acrylate-terminated polyalphaolefin and the thermally triggered free radical stabilizer is beneficial for improving melt flowability and inhibiting early crosslinking during processing, and for forming a highly dense three-dimensional network structure during the crosslinking stage.

The invention discloses a dimerization nitroxide free radical type flow battery positive electrode material as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, carrying out Favorskii rearrangement reaction and extraction on 4-oxo TEMPO, an iodine solution and potassium hydroxide dissolved in ammonia water to obtain pyrrole amide, preparing pyrrole carboxylic acid by utilizing the pyrrole amide, preparing pyrrole dimethyl amide by utilizing the pyrrole carboxylic acid, and then preparing the pyrrole dimethyl amide by utilizing the pyrrole dimethyl amide. Dissolving pyrrole dimethyl amide, adding a lithium aluminum hydride solution, carrying out a reduction reaction to prepare pyrrole methylene dimethyl tertiary amine, and finally carrying out a substitution reaction on the pyrrole methylene dimethyl tertiary amine and the dimer bridging intermediate to prepare the positive electrode material disclosed by the invention. The preparation method is simple in synthesis process and relatively high in reaction yield, and the problem of capacity fading caused by transmembrane permeation of the positive electrode material of the flow battery can be effectively inhibited.

The invention discloses a UV (ultraviolet) curing hot-melt pressure-sensitive adhesive with high cohesive strength. The UV curing hot-melt pressure-sensitive adhesive comprises butyl acrylate, 2-ethylhexyl acrylate, acrylic acid, a benzophenone derivative containing carbon-carbon double bonds, a solvent, an initiator BPO (benzoyl peroxide) and a nitroxide free radical TEMPO. Butyl acrylate and 2-ethylhexyl acrylate are used as main monomers, acrylic acid is used as a functional monomer, the inherent viscosity characteristic of an acrylic pressure-sensitive adhesive is reserved, the initial binding force with a base material is ensured, and a benzophenone derivative containing carbon-carbon double bonds has the dual functions of photo-initiation activity and cross-linking reaction point positions and can be copolymerized with the monomers to realize UV cross-linking; the nitroxide free radical TEMPO captures free radicals at low temperature and releases free radicals at high temperature, so that the molecular weight distribution is uniform, the initiator BPO and the solvent synergistically guarantee stable polymerization, the product is low in melt viscosity at 130-150 DEG C, small molecular chain segments are few, the molecular weight is large under the combined action of the three, and the hot-melt coating is realized while the cohesion strength is high.

The invention discloses a method for photocatalytic synthesis of a free radical initiator alkoxy amine, which comprises the following steps: mixing a compound containing nitroxide free radicals, an organic photocatalyst, peroxide and an organic solvent, and reacting at normal temperature under ultraviolet irradiation; removing the organic solvent, and purifying to obtain alkoxy amine; wherein the organic solvent is selected from at least one of aromatic hydrocarbon compounds, aromatic heterocyclic compounds and ether compounds. According to the method, the low-cost and high-efficiency synthesis of the alkoxy amine is realized under the reaction conditions of normal temperature and ultraviolet light by using a synthesis strategy that an organic photocatalyst and peroxide are used as oxidants. The synthesis conditions are mixed, low temperature is not needed, the method is insensitive to water and oxygen, the light source is more friendly, the operation is simple, and the experiment and industrial amplification difficulty is greatly reduced; a metal photocatalyst is not needed, the bottleneck of yield and cost is broken through, the technical problem of low yield of an existing photocatalysis strategy theory is solved, and the yield can reach 56-91%.

The present application relates to the chemical technology field, specifically to a kind of preparation method of high-purity o-vanillin.The method uses o-methoxyphenylamine as starting material, with chloral hydrate and hydroxylamine hydrochloride is condensed, hydroxylamine oximation reaction, and cyclization reaction is carried out under strong acid condition, and compound 2 is generated;Compound 2 is oxidized under strong base condition, and compound 3 is generated;Compound 3 is esterified with primary alcohol to generate corresponding ester, and then reduction hydrogenation reaction is carried out under the action of strong reducing agent, and compound 4 is generated;Compound 4 is reacted with oxidizing agent in the presence of nitroxyl radical catalyst, and compound 5 is generated;Compound 5 carries out diazotization hydrolysis reaction, and o-vanillin is generated.The method avoids the problem of regioselectivity of traditional formylation reaction through specific reaction sequence, eliminates the generation of isomer impurities from the source, realizes the efficient, environmentally friendly, economic synthesis of high-purity o-vanillin, and provides high-quality raw material guarantee for downstream pharmaceutical.

The invention discloses a pyrrolidine nitroxide free radical connected with a hydrophilic group through a carbon chain, a preparation method of the pyrrolidine nitroxide free radical and application of the pyrrolidine nitroxide free radical in a flow battery. The positive electrode of the aqueous organic flow battery comprises a positive electrode electroactive material and an aqueous solution supporting electrolyte; the positive electrode electrolyte active substance is pyrrolidine nitroxide free radical connected with a hydrophilic group through a carbon chain; and the supporting electrolyte is a single-component or multi-component chloride ion inorganic salt. The hydrophilic group and the pyrrolidine nitroxide free radical are connected through the carbon chain, so that the problems of low water solubility and low stability of the existing pyrrolidine nitroxide free radical serving as a positive electrode electroactive material of the aqueous organic flow battery can be solved at the same time.

The application discloses a halogen-free phosphonate hindered piperidine ammonium salt ionic liquid flame retardant and a preparation method and application thereof, a flame-retardant polypropylene material and a preparation method, and belongs to the technical field of chemical synthesis. The preparation method of the halogen-free phosphonate hindered piperidine ammonium salt ionic liquid flame retardant comprises the following steps: performing a solvothermal reaction on di-ester phosphate and 4-amino hindered piperidine amine as raw materials, and then performing vacuum distillation to obtain the halogen-free phosphonate hindered piperidine ammonium salt ionic liquid flame retardant. That is, the halogen-free phosphonate hindered piperidine ammonium salt ionic liquid flame retardant is synthesized by a one-step method. The nitrogen and phosphorus synergistic effect is utilized to release organic phosphorus and nitrogen free radicals to capture gas phase free radicals during combustion, and the hindered piperidine amine is decomposed to generate non-combustible gas, thereby playing a role of heat absorption and combustible gas dilution. In daily use, the hindered piperidine amine can be converted into stable nitrogen-oxygen free radicals to play a catalytic anti-ultraviolet aging function, and the halogen-free phosphonate hindered piperidine ammonium salt ionic liquid flame retardant has the dual performance of high-efficiency flame retardation and anti-aging.

The application belongs to the field of organic synthesis and particularly relates to a preparation method of ortho-carboxybenzaldehyde. The method comprises the following steps: (a) ring-opening hydrolysis of a compound of formula (3) with a strong alkali solution to prepare a compound of formula (2) or a salt thereof; and (b) oxidation of the compound of formula (2) or the salt thereof with an oxidant in a solvent under the catalysis of a nitrogen-oxygen free radical to prepare a compound of formula (1) or a salt thereof. The ortho-carboxybenzaldehyde prepared by the method is an important intermediate for synthesis of antipyretic analgesics. The method solves the problems of environmental pollution and personnel injury and high energy consumption and cost in the prior art which generally uses bromine, chlorine and a large amount of toxic solvents and high-temperature reflux reaction, and initiatively provides a method for directly ring-opening hydrolysis under the action of a strong alkali and then oxidation in a homogeneous system to prepare ortho-carboxybenzaldehyde, which is simple and convenient to operate, safe and controllable, and suitable for large-scale industrial production.

The application belongs to the technical field of pharmaceutical chemistry, and particularly relates to a gentiopicroside nitroxide radical derivative as well as a preparation method and application thereof. A series of gentiopicroside nitroxide radical derivatives with specific structures are prepared and synthesized through a chemical process. The derivatives exhibit good in-vitro COX-2 enzyme inhibition activity and in-vitro ROS scavenging activity. In-vivo and in-vitro experimental results show that each derivative can effectively inhibit the release of inflammatory mediators and oxidative stress during inflammation, thereby more effectively inhibiting the progress of inflammation and protecting tissues, and the derivatives have a wide application prospect in the preparation of drugs with the efficacy of preventing, relieving or treating inflammation.

Provided are: a method for producing a nitroxide having excellent safety without using a peroxide such as hydrogen peroxide; and a curable composition having excellent curing temperature, curing speed and wettability.　A nitroxide is generated without using a peroxide by simultaneously irradiating a reactive compound with atmospheric-pressure, low-temperature plasma and ultrasonic waves, and a curable composition having excellent curing temperature, curing rate, and wettability can be obtained by constituting the curable composition using the reactive compound containing the nitroxide.

The application discloses a piperidine nitroxide radical derivative containing an ether chain and application thereof to a positive electrode material. The application provides a compound as shown in a formula I. The piperidine nitroxide radical derivative of the application exhibits a low cross-diffusion phenomenon as a positive electrode active material in an organic liquid flow battery, and excellent chemical and electrochemical stability, which jointly promotes the improvement of the cycle life of the organic liquid flow battery. The achievement enhances the practical application value of the organic active material, and promotes the development of a commercialization process.

The application discloses a water-soluble bipolar molecule for a double-electrode flow battery system and a preparation method and application thereof, wherein the water-soluble bipolar molecule material for the double-electrode flow battery system comprises the following preparation steps: S1, acyl chloride reaction is carried out by taking nitroxide piperidinol and acyl chloride as raw materials and adding a catalyst; and S2, quaternary ammonium reaction is further carried out with 1-propanesulfonic acid-4,4'-dipyridine to synthesize the water-soluble bipolar composite molecule structure. The bipolar composite molecule can be used for positive and negative electrode materials of a water-soluble organic flow battery system, so that the influence caused by cross contamination between electrode materials can be avoided, and the stability of battery circulation is improved. Meanwhile, the organic double-electrode flow battery system is suitable for a battery environment using in-situ generated electrolyte, has the advantages of low cost, stable charging and discharging performance, high safety and high solubility of active materials, and can meet large-scale energy storage requirements.