817 results about "Chain reaction" patented technology

The invention relates to a grid steel structure node failure diffusion prediction method, which comprises the following steps of: forming a failure inducement and evolution path model according to a connection form of a bolt-sphere node and a welding node, a stress transfer path, node local yield and fatigue accumulation factors; a diffusion logic of node failure-force flow redistribution-adjacent node stress concentration-chain reaction is constructed; nodes are regarded as middle points of the graph, rod pieces are regarded as edges, and propagation weights between the nodes are defined; the weight parameters are dynamically assigned based on material attributes, node connection types, spatial geometric positions and historical stress states; multi-source monitoring sensors including strain gauges, displacement meters, thermometers and accelerometers are arranged at key nodes of the grid structure, so that node states are sensed; in combination with real-time monitoring data, extracting strain rate change, vibration characteristics, frequency drift and residual deformation key characteristics of each node; a node health state feature vector set is constructed by using time sequence analysis, and the gradual degradation trend of nodes is reflected.

The invention belongs to the technical field of wafer processing, and discloses a multi-section high-flatness wafer cutting method which comprises the following steps: S1, wafer pretreatment and stress buffer layer preparation; s2, performing layered rough cutting by using a diamond blade; s3, plasma fine cutting and interface repairing; s4, performing multi-layer cooling and surface polishing; and S5, surface quality closed-loop detection is carried out. According to the method, copper layer residues and resin carbonization defects are synchronously eliminated. Cryogenic treatment induces lattice reconstruction through ultrafast phase change and blocks a chain reaction of dislocation defects, so that the intrinsic mechanical strength of the material is recovered, and a chemical mechanical polishing system activates the self-repairing characteristic of the material while removing a sub-surface damaged layer through the synergistic effect of abrasive chemical activity and mechanical shearing force, so that an atomic-scale smooth interface is formed, and the self-repairing performance of the material is improved. A closed-loop detection system depends on multi-dimensional data fusion and ion beam fixed-point repair, accurate positioning and performance recovery of cross-scale defects are achieved, and the electrical integrity of a chip functional area is ensured.

The invention discloses a safety risk management and control system for a chemical industry park, particularly relates to the technical field of risk diffusion prediction, and is used for solving the problem that in the prior art, an emergency instruction and a risk propagation path are dynamically mismatched, and cross-regional chain reaction cannot be cooperatively blocked. Environmental parameters and equipment state data are obtained through a data acquisition module, and a fluid correction module extracts a continuous coherent bar code of turbulent vortex to generate a path correction coefficient; the coupling modeling module is combined with a multi-physics field coupling equation to generate dynamic space-time propagation parameters, and the path prediction module predicts a diffusion direction and an influence area according to vector superposition of the parameters and a three-dimensional topological map; the instruction optimization module adjusts the priority and the trigger range of a control instruction, and the execution control module organizes emergency equipment to block a diffusion path according to a preset logic; through dynamic modeling and path matching optimization, time-space cooperation of emergency response and control execution is realized, and the accident diffusion risk of the chemical industry park is significantly reduced.

The invention discloses an antistatic PPO material based on graphene and a preparation method thereof.The preparation method comprises the steps that aminated polyphenyl ether and modified filler react to prepare modified polyphenyl ether, the modified polyphenyl ether is treated with benzenesulfonyl chloride to prepare the antistatic PPO material, when the aminated polyphenyl ether and the modified filler are used, the modified filler is equivalent to a cross-linking agent, and when the modified filler is used for modifying the aminated polyphenyl ether, the modified filler is equivalent to a cross-linking agent; the modified filler is interspersed among the molecular chain segments, graphene is arranged in the modified filler and has a very good conductive effect, so that the material has an antistatic effect, and the surface of the modified filler contains an organic silicon chain segment, so that the antistatic property of the material is improved; when the material is combusted, a phosphorus-containing organic silicon chain segment on the surface of the modified filler can form a P-O-Si compact carbon layer, a nitrogen element on a side chain can generate amino free radicals, then active hydrogen atoms and hydroxyl free radicals are captured, a combustion chain reaction is interrupted, a sulfur element can release sulfur dioxide gas, the oxygen concentration is further diluted, and the oxygen concentration is reduced. Therefore, the material has a good flame-retardant effect.

The invention discloses a comprehensive pipe gallery monitoring and early warning analysis method based on multimode sensing fusion reasoning, relates to the technical field of comprehensive pipe gallery monitoring and early warning, and solves the technical problem that in the prior art, only the risk at the current moment is processed, the potential chain reaction of the risk is ignored, and the risk is spread. According to the method, risk event evolution chains are constructed through development nodes of risk events, and a comprehensive pipe gallery risk evolution network is constructed according to overlapped nodes and index description sets of the risk event evolution chains; the early warning state score of the comprehensive pipe gallery is analyzed; analyzing an early warning consequence score of the comprehensive pipe gallery according to the consequence score of the risk event corresponding to the alarm node; based on the early warning state score and the early warning consequence score, the early warning grade of the comprehensive pipe gallery is analyzed; according to the invention, through the comprehensive pipe gallery risk evolution network, potential risk chain reactions are predicted in advance, and early warning is carried out in time.

The invention provides a tumor exosome (TDEs) fluorescence detection method based on tandem hybrid chain reaction (HCR) and selective coordination, and aims to combine an aptamer, a tandem enzyme-free amplification technology and selective coordination of Cu < 2 + > to analyze a clinical lung cancer blood sample. The programmed cell death ligand 1 (PD-L1) biomarker overexpressed on the surface of the TDEs is selected as a target for detecting the exosome. The HCR can easily generate a large amount of double-stranded DNA, so that the HCR can be used as a means for signal amplification. The high affinity of the aptamer to the protein will affect the tandem HCR reaction and then modulate the HCR product. Cu < 2 + > and a double-stranded DNA product are utilized to form a compound, and a fluorescence signal of calcein can be accurately adjusted, so that accurate fluorescence quantification is performed on the concentration of TDEs.

The invention discloses application of iron ruthenium nano-enzyme in preparation of nucleic acid detection products, and belongs to the technical field of biological detection and nano-materials. The RIN has stable peroxidase-like (POD) activity, and can catalyze a chromogenic reaction between 3, 3 ', 5, 5'-tetramethyl benzidine (TMB) and hydrogen peroxide (H2O2). The catalytic activity of the nano-enzyme can be selectively inhibited by pyrophosphate (PPi) generated in a nucleic acid amplification reaction, so that visual colorimetric analysis on whether target nucleic acid exists or not is realized. In combination with a polymerase chain reaction (PCR) system, the invention constructs a new nucleic acid detection strategy which does not need fluorescence labeling, is simple and convenient to operate and has high sensitivity. Through verification, the system can be widely applied to rapid on-site screening and visual interpretation of related nucleic acid of drug-resistant pathogens (such as ESKAPE flora) and the like, and has a good application prospect.

Safe addressable firing controls positioned within a reusable housing that only allows voltage and current from the shooting panel to reach the explosive device by addressing the switch to open allowing electricity to pass through it and setting off the chain reaction during detonation, wherein the safe addressable firing controls positioned within a cartridge that creates a safety barrier between the surface equipment and a downhole tool, such as an explosive device.

The invention discloses a coal oxidation dynamic evolution multi-parameter real-time monitoring device under ultraviolet radiation, the device comprises a monitoring unit and a reaction unit, the monitoring unit comprises an ultraviolet radiation module, a gas monitoring module, a heat monitoring module, an active group monitoring module, a free radical monitoring module and a control unit, the reaction unit comprises a multi-channel in-situ reaction module and a coal sample reaction cavity, and a monitored coal sample is arranged in the coal sample reaction cavity; the ultraviolet radiation module is used for generating a controllable ultraviolet radiation field on the surface of the coal sample; the gas monitoring module is used for monitoring gas components released in the coal oxidation process in real time; the heat monitoring module is used for monitoring temperature distribution inside and on the surface of the coal sample; the active group monitoring module is used for tracking dynamic evolution of functional groups on the surface of the coal sample. Accurate and high-timeliness coal sample dynamic evolution monitoring is realized, and key data support is provided for revealing a coal oxidation chain reaction mechanism and a spontaneous combustion process.

The invention discloses an industrial equipment linkage control system based on dynamic time sequence reconstruction, relates to the technical field of kiln linkage control, solves the technical problems that a multi-system collaborative dynamic time sequence reconstruction capability is lacked and chain reaction caused by disturbance coupling is difficult to solve, and provides an industrial equipment linkage control system based on dynamic time sequence reconstruction by distinguishing humidity abnormal levels and customizing a heating strategy. The method ensures that heat release is completely matched with a wet material transmission rhythm, improves product drying uniformity, accurately calculates retention time and rotation speed according to a kiln type, realizes a'moisture evaporation demand-rotation speed-retention time 'closed loop, reduces energy consumption, integrates real-time material parameters, waste heat recovery and environment heat dissipation, accurately calculates a heat gap, and performs graded response, so that the energy consumption is reduced, and the energy consumption is reduced. And finally, a cooling air volume-pressure correlation model and an induced draft fan compensation-pressure repair model are established, accurate pressure compensation during cooling strengthening is achieved, and the stability of the microenvironment in the kiln is improved.

The invention discloses a marine ranch breeding equipment reliability evaluation method and system based on a large model, and the method comprises the steps: obtaining the operation parameters of all breeding equipment in a marine ranch, and obtaining an interaction data set between the equipment; constructing a dependency graph model by taking the breeding equipment as nodes; injecting a simulation fault signal into at least one breeding device, and deducing a fault propagation probability by adopting a Bayesian network to obtain a chain reaction path; when the activation value of the node in the chain reaction path exceeds a preset activation threshold value, calculating the overall reliability level according to the path length and the influence weight of the path on the dependency graph model; comparing and analyzing the reliability level with reliability data of each fault record sample in the historical operation log data; when the similar fault scene is matched, it is determined that the overall operation state is abnormal, and meanwhile the corresponding breeding equipment is abnormal, and the hysteresis quality of breeding equipment reliability evaluation in the prior art can be effectively reduced.

The invention provides a lubricating oil production multi-source data fusion analysis method which comprises the following steps: acquiring a stirrer rotating speed signal, acquiring pressure distribution data of a corresponding pipeline, and if the stirrer rotating speed fluctuation range exceeds a preset threshold range, marking that the stirring rotating speed is abnormal; analyzing the pressure distribution change of the pipeline when the stirring rotating speed is abnormal, combining the monitored viscosity change of the oil fluid and the difference of the oil circulating flow speed, and performing fusion calculation to obtain a shear stress distribution index in the pipeline; if the shear stress distribution index is abnormal, the suspension state of oil particles and the deposition rate of pollution particles are detected, and if the suspension state and the deposition rate exceed corresponding preset threshold values, the oil pollution diffusion degree is determined through the suspension state and the deposition rate; and identifying abnormal equipment according to the abnormal signal time sequence correlation, acquiring operation parameters of the abnormal equipment, synchronously analyzing to obtain equipment operation state coupling, analyzing equipment fault chain reaction characteristics, and generating an equipment chain abnormality distribution diagram according to the chain reaction characteristics.

The invention discloses a new energy battery topological insulator fire extinguishing system and a chain reaction suppression method, and the fire extinguishing system comprises a detection module arranged in a battery module; the composite tank is internally provided with a topological insulator composite material, and the topological insulator composite material is a Bi2Te3-coated PFPE compound; and the high-pressure directional release device is connected with the composite tank. According to the invention, the Bi2Te3-coated PFPE compound is injected into the battery module through the high-pressure directional release device, so that a thermal runaway chain reaction can be effectively blocked, secondary reburning is avoided, and the use safety of a new energy battery is greatly improved.

The utility model provides a compressed air foam fire extinguishing device. The compressed air foam fire extinguishing device comprises a pressure container, a compressed air foam generating part, a driving unit and a foam release spray pipe assembly, wherein foam premixed liquid is preloaded in the pressure container; the compressed air foam generating part adopts a shunt damping principle; compressed air foam with a certain foaming multiple is formed in compressed air foam liquid released by the compressed air foam generating part based on the flow division damping principle, the particle size of water can be refined, the coverage area of the water can be increased, more heat can be absorbed, comburent can be efficiently cooled, the penetrating force is improved through the compressed air foam, and the heat efficiency is improved. And the flame retardant can rapidly permeate into comburent to prevent rapid chemical chain reaction in the combustion process.

The invention belongs to the field of food safety detection, and particularly relates to a fluorescence aptamer sensor based on a hybridization chain reaction and application of the fluorescence aptamer sensor. The fluorescent aptamer sensor comprises a nucleic acid aptamer probe, a complementary chain probe and hairpin probes, wherein the hairpin probes comprise a first hairpin probe and a second hairpin probe. The high specificity of the nucleic acid aptamer and the signal amplification of the hybridization chain reaction are utilized, so that the selectivity and the sensitivity of AFM1 detection are improved, the kit has the advantages of isothermal amplification, high specificity, high sensitivity, low cost and the like, and the AFM1 can be simply, quickly, sensitively and specifically detected.

The invention relates to the technical field of dry-type transformers, and discloses a dry-type transformer with a lead-out wire arrangement structure, which comprises a dry-type transformer main body, a control cabinet and a base, and is characterized in that the dry-type transformer main body is connected with the control cabinet through a plurality of wire groups; wire arranging mechanisms with the same number as the wire groups are arranged between the dry-type transformer main body and the control cabinet, and the wire arranging mechanisms are used for independently fixing a plurality of wires in the same wire group. According to the invention, the plurality of independent junction box assemblies are arranged on the wire mounting part, and can be used for separately fixing and arranging a plurality of wires of the same wire group, so that each wire is kept at a safe distance, and the problem of chain reaction of the wires can be avoided.

The invention relates to the technical field of aluminum oxide production, and provides an evaporation station intelligent optimization system based on multivariable coupling regulation, which comprises a DCS (Distributed Control System) lifting module used for optimizing a control strategy and hardware support; the intelligent optimization control module is used for realizing multivariable coupling regulation and control; the data storage and analysis module is used for historical data recording and process analysis; the execution module is used for receiving the control instruction and driving field equipment; the DCS control system lifting module, the intelligent optimization control module and the data storage and analysis module are in bidirectional communication connection in sequence, and the intelligent optimization control module is in unidirectional communication connection with the execution module. Through multivariable coupling regulation and an intelligent algorithm, mother liquor discharging index fluctuation is stabilized, and the operation qualification rate and the alkali circulation efficiency are improved; steam consumption matching is optimized, and energy conservation and consumption reduction are achieved; variable fluctuation chain reaction is reduced, and abnormal response time is shortened; automation of key procedures is promoted, and manual errors are reduced.

The invention provides a single-molecule gene sequencing method based on an MOSFET device, and belongs to the technical field of single-molecule gene sequencing. A grid electrode and a source and drain electrode area of the MOSFET device are coated with a chromium surface and a gold surface in sequence, after the grid electrode is coated with a PMMA coating, a hole only capable of containing single polymerase is developed through high-precision electron beam exposure, and the single polymerase is formed in the hole; the PDMS micro-channel is attached to the periphery of the grid electrode to form a micro reaction chamber, and electronegative polymerase is driven into a high-potential PMMA hole by utilizing a negative pressure circulating scanning method and forms gold-sulfur bond connection with a bottom grid electrode gold atom, so that modification of a single polymerase on the grid electrode is completed. By further upgrading and improving a product-grade MOSFET device, a sequencing technology which takes a single polymerase chain reaction as a sequence information feedback source and realizes high-precision reading of a sequence by utilizing an intrinsic physiological function of biomolecules is formed, and an effective signal analysis method is constructed, so that the information reading effectiveness is improved, and the accuracy of information reading is improved. The accuracy and the high efficiency of a single molecule sequencing technology are improved.

The invention relates to the technical field of chemical-looping hydrogen production, and discloses a self-heating type chemical-looping hydrogen production and in-situ decarburization system and method.Hydrocarbon fuel is converted into hydrogen and carbon dioxide through a chemical-looping circular reaction, and meanwhile coupling of CO2 trapping and separation on the source side and chemical-looping hydrogen production of the hydrocarbon fuel is achieved through an absorbent; on the basis of in-situ separation of CO2, the hydrocarbon fuel conversion rate and the hydrogen yield are improved, the requirement for equipment needed by production is lowered, and meanwhile the energy efficiency level of a hydrogen production system is improved. Besides, the system can realize self-heating chemical looping hydrogen production and in-situ decarburization without external heat input through matching of a hydrogen production raw material, an oxygen carrier and CO2 absorbent particles, endothermic reduction of the oxygen carrier in the hydrogen production decarburization reactor and in-situ absorption and heat release of CO2, so that a series of problems of limited heat and mass transfer performance and the like existing in external heat driven chemical looping reaction are solved; and self-heat balance in the system can be realized, and the universality of the chemical looping technology is improved.

The invention relates to the field of flame-retardant materials, in particular to a flame-retardant PC composite material and a preparation method thereof.According to the flame-retardant PC composite material, graphite-modified polycarbonate can improve the flame retardant property of polycarbonate, holes formed when the graphite-modified polycarbonate is heated can play roles in smoke abatement and heat preservation, the overall compatibility is good, dispersion is uniform, and the flame-retardant PC composite material is prepared. In addition, the modified organic silicon balls D, the modified nano silicon balls A and the like are compounded to be used for quenching a combustion chain reaction, isolating oxygen, achieving flame retardance and toughening and reinforcing the polycarbonate base material, and holes in the modified carbon balls C can be used for rapid heat dissipation and prevention of continuous combustion. Meanwhile, oxygen which cannot be isolated by the blocking layer can be diluted, the modified nano silicon spheres B can be used for retarding flame and eliminating smoke, and the defect that the mechanical property of the composite material is reduced due to the formation of holes in a system can be overcome, so that the composite material has relatively high mechanical property while realizing good flame retardance and smoke abatement property.

The invention discloses a risk assessment method and system for chemical leakage, and relates to the technical field of risk assessment. A risk assessment system for chemical leakage comprises a chemical three-dimensional construction module, a chemical leakage simulation module and a chemical leakage assessment module. According to the method, the chemical three-dimensional distribution model is constructed, so that the types, reserves and space structures of the chemicals in the region are comprehensively perceived, and the authenticity and space accuracy of leakage simulation are enhanced; a chemical compatibility matrix and a logic adjacency chain diagram are introduced, so that a potential chain reaction path is effectively identified, and the pre-judgment capability of a complex accident coupling risk is improved; a leakage space prototype is set based on a leakage point, and a surrounding building model is constructed, so that risk assessment has structured and local response capabilities, and the comprehensive influence of building purposes, function sensitivity and exposure conditions can be reflected.

The present invention generally relates to droplets and / or emulsions, such as multiple emulsions. In some cases, the droplets and / or emulsions may be used in assays, and in certain embodiments, the droplet or emulsion may be hardened to form a gel. In some aspects, a heterogeneous assay can be performed using a gel. For example, a droplet may be hardened to form a gel, where the droplet contains a cell, DNA, or other suitable species. The gel may be exposed to a reactant, and the reactant may interact with the gel and / or with the cell, DNA, etc., in some fashion. For example, the reactant may diffuse through the gel, or the hardened particle may liquefy to form a liquid state, allowing the reactant to interact with the cell. As a specific example, DNA contained within a gel particle may be subjected to PCR (polymerase chain reaction) amplification, e.g., by using PCR primers able to bind to the gel as it forms. As the DNA is amplified using PCR, some of the DNA will be bound to the gel via the PCR primer. After the PCR reaction, unbound DNA may be removed from the gel, e.g., via diffusion of washing. Thus, a gel particle having bound DNA may be formed in one embodiment of the invention.

The invention provides a method for synchronously inverting unsaturated soil solute reaction parameters, and belongs to the technical field of software development. The method comprises the following steps: establishing an initial model for simulating chain reaction migration of solutes in unsaturated soil based on HYDRUS-1D software, and generating a corresponding input file; based on observation data of the one-dimensional vertical infiltration test, determining a plurality of solute reaction parameters to be synchronously inverted and an initial value range thereof; adopting a genetic algorithm to randomly generate an initial population containing multiple groups of parameter combinations in the initial value range; performing solute transport simulation on each group of parameter combination in the population, and automatically extracting a simulation result; calculating a fitness value corresponding to each parameter combination based on the observation data and the simulation result obtained in the step S4; and iteratively optimizing, and judging whether a termination condition of the genetic algorithm is met or not. By optimizing a software running program and adjusting automatic extraction and processing of calculation parameters, efficient and continuous soil solute transport analysis is realized.

The invention provides a fully synthetic cutting fluid special for a copper part and a preparation process thereof. The fully synthetic cutting fluid special for the copper part comprises the following raw materials in parts by weight: 0.5-2.0 parts of a defoaming agent, 1.0-3.0 parts of an antioxidant, 0.5-2.0 parts of a corrosion inhibitor, 2.0-5.0 parts of a surfactant, 0.5-1.5 parts of a metal ion complexing agent and 80.0-100.0 parts of deionized water. Wherein the antioxidant is prepared from carnosol, daidzin and butylated hydroxytoluene. The carnosol and the daidzin can be used for reducing the oxidation reaction by capturing free radicals, and the butylated hydroxytoluene can be used for further enhancing the anti-oxidation effect by interrupting the oxidation chain reaction. And through the combined action and mutual complementation of different anti-oxidation mechanisms, a synergistic effect is formed, and oxidation of the copper part in the machining process is effectively prevented. Wherein the metal ion complexing agent is composed of isothiocyanate, polyaspartic acid and amino trimethylene phosphonic acid, multiple protection mechanisms are formed, and the corrosion resistance of the copper part is remarkably improved. And the existence of the metal ion complexing agent is also beneficial to improving the stability of the cutting fluid.

The present document describes methods and systems for amplifying and quantifying amplification of a nucleic acid molecule, with a polymerase chain reaction (PCR) or a loop-mediated isothermal amplification (LAMP), by irradiating, with a heating activation light beam from a continuous wave laser a biological enzymatic reaction mixture in solution comprising a nucleic acid template, a polymerase enzyme, and chemically modified nanoparticles. Quantification of the amplification is achieved by irradiating the biological enzymatic reaction mixture during an annealing and / or elongation steps with an ultraviolet (UV) light source and measuring with a photodetector a transmission change in UV light transmission.

The invention discloses a preparation method of reactive antioxidant grafted modified nylon 6 and a film thereof, and belongs to the technical field of nylon modification. A reactive antioxidant containing a hindered phenol structure and nylon 6 are subjected to melt chemical grafting to form a covalent bond combined nylon 6-antioxidant system, and hindered phenol provides hydrogen atoms and can be combined with free radicals generated in the aging process, so that the chain reaction of the hindered phenol is terminated, and phenoxy free radicals with low activity are formed by the hindered phenol. According to the invention, the reactive antioxidant grafted modified nylon 6 is further processed into a film product, and the nylon 6 film product prepared by the method has the advantages of less antioxidant migration, aging resistance, high mechanical property retention rate and the like.

The invention relates to an organic combined polluted underground water in-situ remediation method based on a micro-nano iron-based material. The method comprises the following steps: acquiring underground water pollution information; establishing a composite reaction zone at a preset position, and constructing a reduction-oxidation chain reaction system; and operating the composite reaction zone, collecting monitoring data, and optimizing the composite reaction zone until the composite pollution is degraded and removed to a preset value. Through series reaction of powerful reduction of the micro-nano iron-based material and advanced oxidation of the iron-based activated persulfate, the performance of the micro-nano iron-based material serving as a strong reduction material and an active agent is fully played, pollutants such as halogenated hydrocarbon in underground water are sequentially subjected to reduction degradation, pollutants such as benzene series and volatile phenol are sequentially subjected to oxidative degradation, and the pollution to the underground water is reduced. Effective management and control of underground water combined pollution of medical and chemical parks and enterprises are realized; a monitoring well is configured based on a composite reaction zone, and remediation materials are discontinuously added in combination with management and control conditions, or other management and control materials are flexibly selected, so that long-term management and control of groundwater pollution risks are realized.

The invention provides a cooperative control method for a power grid and associated power plants and related equipment, and in the method, a real-time power grid load and a grid-connected point voltage between each power plant and the power grid need to be acquired firstly, so that power grid operation monitoring is carried out according to the real-time power grid load and the grid-connected point voltage of each power plant. When at least one of the real-time power grid load and the voltage of each grid-connected point triggers a preset abnormity judgment rule, abnormal fluctuation data are determined, and at least one of active power and reactive power of at least one power plant is adjusted according to the abnormal fluctuation data, inverter power characteristics of each power plant and system inertia data of the power grid, so that the power grid load is determined; and the connection between the power grid and the load end and each power plant is maintained. Therefore, the active and reactive conversion relation in each power plant can be fully considered, chain reaction caused by adjustment lag of single equipment is avoided, and the operation stability of a power grid is ensured.

The invention provides a boron drug with tumor targeted release capability for boron neutron capture therapy and a preparation method thereof, relates to the technical field of tumor therapy, and provides a boron drug which can be activated through high-concentration NAD (P) H at a tumor site and can release a B-10 drug in a targeted manner for boron neutron capture therapy. A boron-10-containing compound in the boron medicine is connected with 3-aldehyde quinoline salt through a self-elimination reactive group, the 3-aldehyde quinoline salt can be specifically reduced by NAD (P) H rich in tumor cells to trigger chain reaction, and the effective boron-10 compound is released for boron neutron capture therapy. The damage to normal cells in the BNCT process can be effectively reduced by a method for targeted aggregation of the boron drug in the tumor cells. The boron drug synthesis method is simple, mild in condition and high in yield, has the advantages of stable chemical property, good light stability, small toxicity and the like, and provides a good application prospect for the field of boron neutron capture therapy.

The invention discloses a nucleic acid detection sensor based on S9.6 antibody bivalent capture, and belongs to the technical field of biological detection. The sensor comprises hairpin probes H0, H1 and H2, a single-chain probe I and an electrode or a chip which is self-assembled with an S9.6 antibody, the single-chain probe I is used for initiating H1 and H2 to generate a hybridization chain reaction so as to prepare a signal amplification material, in the presence of target nucleic acid, the hairpin probe H0 is recognized and opened and is hybridized with the prepared signal amplification material so as to form a compound, the compound contains two sections of DNA / RNA double strands, the DNA / RNA double strands are specifically recognized by an S9.6 antibody so as to be captured on a sensing interface, and the DNA / RNA double strands are captured by the S9.6 antibody. And determining the content of target nucleic acid by analyzing the signal change on the sensing interface. The method is suitable for any single-stranded nucleic acid detection, the detection process is simple, convenient and rapid, and high-sensitivity detection performance is obtained.