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41results about How to "Sensitive high" patented technology

Bidirectional milling force prediction method and system

The invention discloses a bidirectional milling force prediction method and system, and the system comprises a data obtaining module which is used for obtaining a current and milling force data set; a preprocessing module; a feature extraction module; the feature screening module is used for screening out current features meeting a preset condition to form a target feature matrix according to the stability of the current features, the sensitivity of the current features to the rotating speed and the correlation between the current features and the milling force; the initial module is used for constructing a neural network model based on a CNN-ResNet deep learning algorithm; the training module is used for obtaining a final prediction model for predicting the bidirectional milling force; the input module is used for inputting the target characteristic matrix of the current of the cutter with the milling force to be monitored into the prediction model; and the output module is used for outputting the bidirectional milling force predicted by the prediction model. The bidirectional milling force Fx and the bidirectional milling force Fy in the feeding direction and the direction perpendicular to the feeding direction can be predicted, and the prediction and monitoring accuracy is high; and the method can be suitable for complex cutting conditions and material changes.
Owner:JIANGSU UNIV OF SCI & TECH

Automobile transmission shaft with kinetic energy recovery function

The invention discloses an automobile transmission shaft with a kinetic energy recovery function, and relates to the technical field of vehicle transmission. The problem of torque transmission vibration energy recovery is solved. The driving shaft is in transmission connection with a vehicle driving source, the driven shaft is in transmission connection with a vehicle driving wheel, the transition shaft is used for being in transmission connection with the driving shaft and the driven shaft, and the energy recovery part is fixed to a vehicle body. The opposite sides of the driving shaft and the transition shaft are each provided with a set of pawls. The driving shaft and the transition shaft are arranged, the driving shaft and the transition shaft are meshed and matched through the pawls, meanwhile, energy conversion is conducted through piezoelectric ceramics, so that second-order vibration energy in the forklift driving or forklift driving process can be absorbed and converted, energy recovery is achieved, meanwhile, a rubber cushion block is arranged, on one hand, vibration buffering can be conducted to a certain degree, and on the other hand, the energy recovery efficiency is improved. And on the other hand, the piezoelectric ceramics can be prevented from being damaged when being driven by a relatively large torque.
Owner:四川吉利学院

Cavity-enhanced Fabry-Perot interference resonant cavity

The invention discloses a cavity enhanced Fabry-Perot interference resonant cavity, and belongs to the technical field of sensing detection. The transduction film is used as a transduction medium, vibration is generated through induction, signals are converted into vibration of the film, optical signals are modulated, and information to be measured can be obtained. According to the invention, the cavity enhancement structure is introduced, the optical fiber collimator and the transduction film jointly form an interference resonant cavity, and the phase sensitization of the optical microcavity is realized by improving the reflectivity of the cavity and prolonging the time of capturing light. Through stable interference of the resonant cavity, strong optical constraint is generated, and interaction between a light beam and a transmission signal is enhanced. In addition to the characteristics of high sensitivity, small loss, small size and high integration, the device has high expandability in the design aspects of bandwidth and sensitivity, and good sensing performance and design flexibility of the device provide a new opportunity for propelling the military and civil fields such as monitoring technology and biomedicine.
Owner:HUAZHONG UNIV OF SCI & TECH +1

High-sensitivity underwater flexible touch sensor and pressure detection method

ActiveCN119124415Astable structureThe relative position of the structure is stableForce measurementUnderwaterTouch Senses
The invention discloses a high-sensitivity underwater flexible touch sensor and a pressure detection method. The sensor comprises a top porous boss layer, an upper interlocking layer, a middle layer and a lower interlocking layer which are sequentially and coaxially arranged from top to bottom. A closed cavity is formed between the upper interlocking layer and the lower interlocking layer, the cavity is filled with insulating hydraulic oil, the upper interlocking layer is provided with an upper-layer interlocking microstructure, the lower interlocking layer is provided with a lower-layer interlocking microstructure, and the upper-layer interlocking microstructure, the lower-layer interlocking microstructure and the middle layer are all located in the cavity; the middle layer comprises a middle layer flexible substrate, and a sensitive material and a flexible electrode which are arranged above the middle layer flexible substrate, and the sensitive material adopts a patterning design and is electrically connected with the flexible electrode; according to the method, the water pressure is compensated in the aspects of structure and data processing, and high-precision pressure values can be output under different water pressures. According to the underwater flexible touch sensor, high-sensitivity and low-interference detection of the contact force can be realized when the underwater flexible touch sensor works in different depth environments.
Owner:ZHEJIANG UNIV

Kit for detecting hepatitis E virus RNA (Ribonucleic Acid) based on RAA / PCR-CRISPR-Cas13a

InactiveCN119120774Ahighly specific detectionSensitive highMicrobiological testing/measurementMicroorganism based processesNucleic acid detectionHepatitis E virus RNA
The invention discloses a kit for detecting RNA (Ribonucleic Acid) of a hepatitis E virus based on RAA (Reverse Amplification Amplification) / PCR (Polymerase Chain Reaction)-CRISPR-Cas13a. The kit comprises a primer pair used for amplifying or detecting an HEV conserved gene segment (SEQ ID No.1) and crRN A, and the sequence of crRNA is composed of an anchoring sequence and a guide sequence (39-66th sites of SEQ ID No.13). Based on a CRISPR-Cas13a nucleic acid detection technology, through design, construction and screening, a set of RAA amplification primer pair or PCR primer pair for hepatitis E virus RNA detection, crRNA and a detection method thereof are finally provided, the crRNA can realize high-sensitivity and high-specificity detection of hepatitis E virus RNA by activating Cas13a, and the sensitivity reaches 1 copy / mu L. The method is simple, convenient and rapid, and has important application value.
Owner:BEIJING YOUAN HOSPITAL CAPITAL MEDICAL UNIV

High-sensitivity flexible porous sensor and 3D printing preparation method thereof

The invention relates to a high-sensitivity flexible porous sensor and a 3D printing preparation method thereof.The product comprises a sensor body, the two ends of the sensor body are connected with wires, and the sensor body is a multi-layer composite material formed by stacking and arranging a plurality of fuses up and down; the fuses in any layer of the sensor main body are arranged in parallel; an interlayer hole is formed between any two adjacent layers of fuses of the sensor main body; micropores are formed inside and on the surface of the fuse wire; the fuse wire comprises a polymer matrix and a conductive filler uniformly distributed in the polymer matrix; the polymer matrix is a polymer which can generate volume change when external conditions change; during preparation, a fusion 3D printing technology is adopted, a composite material system is fused and then extruded from a spinning nozzle to form fuses, the fuses are stacked up and down to obtain a sensor main body, and the two ends of the sensor main body are connected with wires to form the high-sensitivity flexible porous sensor. The product disclosed by the invention has the characteristics of high sensitivity and flexibility, and has various stimulation responses; the preparation method is simple.
Owner:DONGHUA UNIV

ZIF-8 (at) MB / AuNPs ratio type electrochemical sensor, preparation method thereof and parathion-methyl detection method

The invention relates to the technical field of electrochemical sensing, in particular to a ZIF-8 (at) MB / AuNPs ratio type electrochemical sensor, a preparation method of the ZIF-8 (at) MB / AuNPs ratio type electrochemical sensor and a detection method of parathion-methyl. The ratio-type electrochemical sensor constructed by the method can realize the detection effects of high sensitivity, high speed and high precision on parathion-methyl, is good in anti-interference performance and repeatability, and has potential application prospects in the field of quality detection of agricultural products.
Owner:JIANGSU UNIV OF TECH

Chlorophyll fluorescence continuous monitoring system and method based on miniature laser radar

The invention discloses a chlorophyll fluorescence continuous monitoring system and method based on a miniature laser radar. According to the method, non-invasive detection and analysis are carried out on plants by utilizing a sensing technology, a spectrum technology and an imaging technology through a non-destructive detection technology under the condition that the tissue structure and chemical components of the plants are not damaged. The system comprises a transmitting circuit, a detection circuit, a double-layer optical filter and a core processor. According to the method, photosynthetically active radiation can be calculated by acquiring leaf fluorescence constant signals, ambient light information and ambient temperature information; and the chlorophyll fluorescence quantum productivity is calculated by combining a chlorophyll fluorescence measurement method, so that the detection method for quantifying chlorophyll fluorescence on the leaf canopy level is realized. The modulated fluorescence technology disclosed by the invention has the characteristics of rapid, simple, sensitive and reliable measurement, no interference on a sample, capability of measuring under the condition of ambient light and the like, and plays an effective role in promoting solving of a plurality of ecological key problems.
Owner:NANJING NORMAL UNIVERSITY

A new power system grid fault feature analysis method

The application relates to a novel power system grid fault feature analysis method, first, four-dimensional data of alternating current side electrical quantity, direct current side conversion parameter, equipment operation state and environmental meteorological parameter are integrated, and the integrated data is subjected to noise reduction, normalization, missing value completion and abnormal value elimination treatment, so that a standardized feature sample set is formed, then, an improved wavelet packet transform is adopted to decompose a transient signal, time domain, frequency domain and time-frequency domain features are extracted, so that a high-dimensional fault feature matrix is constructed, then, a fault feature secondary verification is realized in a mode of combination of cosine similarity and dynamic time warping; meanwhile, a graph convolution network is introduced, fault contribution degrees of each node are calculated in combination of a power grid topological structure and a power flow distribution, a fault source is accurately positioned, a fault propagation path is combed, and a fault influence range is quantified; and the application has the advantages of comprehensiveness, high efficiency, accuracy and strong adaptability.
Owner:XUCHANG POWER SUPPLY COMPANY OF STATE GRID HENAN ELECTRIC POWER

Highly sensitive immunoassay reagent and measurement method

PendingEP4317991A4accurate measurementSimple and accurate measurementBiological testingImmunoassays
Provided are a highly sensitive measurement reagent and a measurement method to make it possible to accurately and conveniently measure the sCLEC-2 concentration in blood even at the level of healthy persons. The measurement reagent contains a carrier on which a first immunological partner that binds to a physiologically active substance contained in a biological sample is immobilized; a second immunological partner that binds to the physiologically active substance; and an amphiphilic substance that contains, as a hydrophobic portion, a linear, branched, or cyclic saturated or unsaturated hydrocarbon group with 6 to 12 carbons, an aromatic hydrocarbon group with 6 to 12 carbons, or a steroid skeleton; or a chaotropic substance.
Owner:PHC CORP

Primer probe combination, method and application of RPA-LFD rapid detection of Ayu sutsugamushi

The present invention discloses a primer-probe combination, method and application for rapid detection of sweetfish larvae by RPA-LFD, belonging to the field of biotechnology. The primer-probe combination consists of an upstream primer with a sequence as shown in SEQ ID NO.3, a downstream primer with a sequence as shown in SEQ ID NO.4 and a probe with a sequence as shown in SEQ ID NO.7. The RPA-LFD detection method for sweetfish larvae established based on the primer-probe combination has the advantages of high sensitivity, good specificity, simple operation, and visualized results. It can accurately detect sweetfish larvae and effectively reduce the economic losses caused by sweetfish larvae disease. The RPA-LFD rapid detection method for sweetfish larvae provided by the present invention does not require special instruments, has simple sample processing, rapid amplification, and intuitive results. The minimum detection limit of the sample can reach 9.38×10 ‑6 ng / μL, 1000 times higher than traditional PCR methods.
Owner:QINGDAO AGRI UNIV

SERS (Surface Enhanced Raman Scattering) flexible sensor based on dual-ion modification as well as preparation method and application thereof

PendingCN121954838Ahigh selectivityhigh sensitivityRaman scatteringIonophoric ActivityKynurenic acid
The invention discloses an SERS (Surface Enhanced Raman Scattering) flexible sensor based on dual-ion modification as well as a preparation method and application of the SERS flexible sensor, and belongs to the technical field of biomedical detection. A bacterial cellulose membrane (BCM) is used as a base material, cation modification (QBCM) is carried out through glycidyl trimethyl ammonium chloride (EPTMAC), anion modification (TABCM) is carried out through tannic acid (TA), a functional substrate with asymmetric charge distribution and a porous structure is constructed, then Ag NPs are loaded on the modified base material through an in-situ reduction method, the QBCM-coated AgNPs and TABCM-coated AgNPs dual-ion active substrate is formed, and the AgNPs / TABCM-coated AgNPs dual-ion active substrate is used for preparing the composite material. The SERS flexible sensor is integrated through a layer-by-layer self-assembly (LbL) technology; the SERS flexible sensor can realize specific enrichment and synchronous detection of anionic kynurenic acid (KYNA) and cationic spermine (Spm) in urine, and is low in detection limit and good in reproducibility.
Owner:FUJIAN NORMAL UNIV

An electrochemical microneedle biosensor and a preparation method thereof

The invention discloses an electrochemical microneedle biosensor and a preparation method thereof. The biosensor is a three-electrode system, comprising a working electrode, a counter electrode and a reference electrode, wherein the substrate materials of the three electrodes are all silicon-based high-density microneedle arrays; wherein the working electrode is a silicon-based high-density microneedle with a sputtered gold layer, gold nanoparticles with a dendrite structure are deposited on the surface, and a carcinoembryonic antigen (CEA) aptamer with high specificity is combined through an Au-S bond; the electrochemical microneedle biosensor provided by the invention adopts a high-density silicon-based microneedle array to construct a three-electrode system to detect carcinoembryonic antigen in tissue fluid, the working electrode has gold nanoparticles with a dendrite structure, and the active surface area is preferably increased, the patch-type structure with three electrodes in one is easy to operate, can realize non-invasive rapid detection, and has high detection sensitivity, good specificity and low detection limit, thereby providing a simple and quick method for detecting tumor biomarkers such as carcinoembryonic antigen.
Owner:GRIMAT ENG INST CO LTD +1

A method for quickly detecting moisture in tobacco leaf processing

The invention discloses a method for quickly detecting moisture in tobacco leaf processing. 2+ As the precursor material, dimethyl sulfoxide (DMSO) was used as the solvent. Solvent-dependent rhein-based carbon dots were prepared by microwave method. The interaction between water and aprotic solvent DMSO was used to reduce the fluorescence signal of carbon dots. Combined with smartphone RGB signal acquisition technology, a new method with high sensitivity and selectivity for moisture determination was established by using the good linear relationship between moisture content and R value. The detection limit was 5 mg. This method was applied to the detection and analysis of moisture content in tobacco leaf processing, and the results were consistent with those of the reduced pressure drying method. The method is simple, stable and accurate.
Owner:CHINA TOBACCO GUANGXI IND

Near-infrared response type asymmetric polymethine cyanine dye as well as preparation method and application thereof

The invention provides a near-infrared response type asymmetric polymethine cyanine dye as well as a preparation method and application thereof. The dye has a structure as shown in a general formula I. The probe is combined with H < + > through an azaindole part in an asymmetric polymethine cyanine dye structure, so that rapid and reversible response to pH change is realized. The probe has high sensitivity and high specificity on pH, the pKa value is 6.46, the pH response linear range is 5.0-7.0, and the probe is suitable for monitoring the pH value in mitochondria. Due to inherent positive charges of the structure, the material can be gathered in mitochondria in a targeted manner and is kept stable in an autophagy process. The probe has the characteristics of high sensitivity, reliability and visualization, and is suitable for the fields of basic scientific research, drug action mechanism evaluation, cell physiological function and disease model analysis, environmental pollutant effect monitoring, regenerative medicine and the like. In addition, the probe is good in biocompatibility and high in light stability, is compatible with common fluorescence imaging equipment, and is convenient to popularize and apply.
Owner:DALIAN UNIV OF TECH

Gold-silver nanoclusters, preparation method and application thereof in electrochemiluminescence-electrochemical dual-mode detection of chloramphenicol

This invention belongs to the field of electrochemiluminescence materials technology, and discloses a gold-silver nanocluster, its preparation method, and its application in the electrochemiluminescence-electrochemical dual-mode detection of chloramphenicol. The preparation method involves adding a silver source solution to a gold source solution, then adding an alkaline thiol β-cyclodextrin solution to obtain a mixed solution. Sodium bicarbonate is added to adjust the pH to 8.2-8.4, followed by incubation to obtain a crude product of gold-silver nanoclusters. The crude product is then purified by centrifugation and dialyzed to obtain the gold-silver nanoclusters. Furthermore, this invention uses these gold-silver nanoclusters as an ECL luminescent material to construct a sensor and applies it to the quantitative detection of chloramphenicol. This sensor innovatively achieves synergistic detection of ECL and DPV dual signals, with mutually verifiable detection results, exhibiting high sensitivity, excellent selectivity, good stability, and excellent repeatability.
Owner:WEIFANG UNIV OF SCI & TECH

Micro-ecological flora balanced natural cranberry nourishing and improving causalgia and peculiar smell moisturizing and tightening essence, preparation method and application of micro-ecological flora balanced natural cranberry nourishing and improving causalgia and peculiar smell moisturizing and tightening essence

The invention discloses a micro-ecological flora balanced natural cranberry essence capable of nourishing and improving causalgia and peculiar smell, a preparation method and application, the cranberry essence is prepared from the following raw materials in percentage by weight: 12-25% of cranberry oil, 70-85% of cyperus esculentus oil and 3-5% of pepper fruit extract. The composition can promote the growth of beneficial bacteria, inhibit the growth of harmful bacteria, maintain the balance of micro-ecological flora, improve the skin elasticity, provide a moistening effect, enhance the barrier function of the skin, protect the skin from being damaged by the external environment, reduce skin sensitivity, reduce skin discomfort, relieve pruritus, and reduce stabbing pain and burning heat sensation. The disposable hygienic product prepared from the essence can keep micro-ecological flora balance and reduce skin discomfort. The wash supplies prepared from the essence are externally smeared on the skin, so that the skin has skin care activity, and the essence has good effects of inhibiting harmful bacteria, delaying skin degenerative change and moisturizing and tightening the skin.
Owner:KINGDOM HEALTHCARE HLDG LTD GUANGDONG

Generator-transformer unit intelligent fault diagnosis and tripping control method, system and device based on double microcomputer protection and storage medium

PendingCN121791056AStable electrical inputHigh reliability data redundancyElectrical testingEmergency protection detectionMicrocomputerTransformer
The invention discloses a generator-transformer unit intelligent fault diagnosis and tripping control method, system and device based on double microcomputer protection and a storage medium, and relates to the technical field of generator-transformer unit microcomputer protection and intelligent control. Constructing a multi-dimensional non-electric quantity sensing system based on the standardized electric quantity data, performing synchronous alignment and logic fusion on electric quantity and non-electric quantity signals by using a communication model, and outputting a state data set; the method comprises the following steps: performing intelligent fault identification and self-adaptive criterion generation, determining fault types, ranges and confidence coefficients, calling the self-adaptive criterion to establish hierarchical tripping and delay control logic, mapping fault levels into quick-break, delay and trend three-level action channels, and performing multi-source criterion collaboration and shunt output control through an arbitration mechanism among double devices. According to the method, the threshold value and the time delay can be dynamically adjusted according to different operation conditions, and accurate judgment of the fault type, the fault range and the confidence coefficient is achieved.
Owner:GUANGDONG DATANG INT CHAOZHOU POWER GENERATION CO LTD

Combined marker for predicting acute myocardial infarction, detection kit and application

The invention relates to new application of small molecule metabolites such as decanoyl carnitine (CN C10: 0), lauroyl carnitine (CN C12: 0), glutamine, prolyl-leucine, oleic acid and S-adenosine homocysteine in a plasma sample as combined markers in preparation of a kit for predicting acute myocardial infarction patients in subjects. The invention further relates to a kit for detecting acute myocardial infarction patients in subjects, the relative concentrations of the combined markers in blood plasma of the subjects are detected, variables of the combined markers are calculated on the basis of a binary logistic regression equation, and the acute myocardial infarction patients in the subjects are detected on the basis of determined intercept point values. And predicting whether the subject has the risk of acute myocardial infarction or not. The kit can realize high-sensitivity detection of several metabolites involved in the invention, and has the characteristics of low detection cost and good repeatability. The combined use of the small molecule metabolites can be applied to the clinical diagnosis of auxiliary prediction of acute myocardial infarction, and has high development and application values.
Owner:FIRST AFFILIATED HOSPITAL OF DALIAN MEDICAL UNIV

Turn-On type fluorescent polymer, synthesis method thereof and application of Turn-On type fluorescent polymer in uranyl ion detection

The invention belongs to the technical field of environment detection, and particularly relates to a Turn-On type fluorescent polymer, a synthesis method thereof and application of the Turn-On type fluorescent polymer in uranyl ion detection. The structural characteristics of tetraphenylethylene tetraaldehyde are ingeniously utilized, the fluorescent polymer TPE-COPs with fluorescence enhancement response to uranyl ions is synthesized at normal temperature, and the fluorescent polymer is a Turn-On type fluorescent polymer and has the advantages of high sensitivity, high selectivity, quick response and the like in the aspect of uranyl ion detection. The sensitivity and the anti-interference capability can be improved at the same time, the detection limit, the detection range and the selectivity are comprehensively considered, and huge potential and value are shown in biomedical research and application. Meanwhile, the fluorescent polymer TPE-COPs can be prepared at room temperature, the process is simple, high-temperature, high-pressure, oxygen-free and other harsh environments are not needed, and the fluorescent polymer TPE-COPs is more suitable for industrial large-scale production and application.
Owner:GUANGZHOU UNIVERSITY

CrRNA target spot and CRISPR-Cas13a system for detecting Hendea virus

The invention discloses a crRNA target spot and a CRISPR-Cas13a system for detecting a Hendea virus. The CRISPR-Cas13a system comprises Cas13a protein and crRNA, or a complex formed by the Cas13a protein and the crRNA; the crRNA comprises an anchoring sequence used for being combined with Cas13a protein and a guide sequence targeting a Hendea virus target sequence; the Hendea virus target sequence is located at the 632 to 659 sites of a Hendea virus genome. Experiments prove that the crRNA disclosed by the invention can realize high-sensitivity and high-specificity detection on Hendea virus nucleic acid by activating Cas13a, and the sensitivity reaches one copy (1copy / [mu] L); the method has an important application value.
Owner:ACADEMY OF MILITARY MEDICAL SCIENCES

Fluorescent sensor for detecting endocrine disruption activity in sewage and application

The invention relates to the technical field of biological monitoring, in particular to a fluorescence sensor for detecting endocrine disruption activity in sewage and application. A Y-type polypeptide containing an anchoring region, a hinge region and an antifouling region is creatively designed as a structural skeleton, and the tail ends of a main chain and a branch chain are respectively subjected to directional modification to prepare the multifunctional ligand-polypeptide-dye conjugate; an optical biosensing chip, namely a ligand-polypeptide-dye conjugate functionalized biosensing chip which is high in reaction efficiency, strong in anti-pollution characteristic and capable of being stably regenerated, is constructed by adopting a covalent coupling method, and then the quantum dot-nuclear receptor fluorescent probe which is high in sensitivity and adjustable in emission spectrum is prepared. The ratio fluorescence biosensing principle based on fluorescence resonance energy transfer is provided, rapid quantitative detection of the endocrine disruptors in sewage is achieved, and the endocrine disruptors have broad-spectrum specific recognition capacity on a certain type of endocrine disruptors.
Owner:SHENZHEN UNIV

Compositions, kits and methods for detecting ebv-associated nucleic acid markers

PendingCN122503548AAccurate detectionAccurate basis
The application relates to the technical field of biological detection, and discloses a composition, a kit and a detection method for detecting an EB virus related nucleic acid marker. The composition provided by the application comprises primers for detecting EB virus mRNA and EB virus derived miRNA. Through the combined use of specific primers designed for specific EB virus mRNA and EB virus derived miRNA, the application can realize rapid, high-specificity and high-sensitivity detection of the EB virus, thereby providing more accurate diagnosis information for the subsequent treatment and prevention and control of EB virus infection.
Owner:SANSURE BIOTECH INC

Kit for detecting hepatitis delta virus RNA (Ribonucleic Acid) based on RAA-CRISPR-Cas13a

The invention discloses a kit for detecting hepatitis D virus RNA (Ribonucleic Acid) based on RAA-CRISPR-Cas13a, and belongs to the technical field of nucleic acid detection. In order to solve the technical problem of how to rapidly detect or identify the hepatitis D virus, the invention provides a composition, the composition comprises an RAA primer pair and crRNA, the RAA primer pair is composed of two single-stranded DNAs with nucleotide sequences of a sequence 3 and a sequence 7, and the nucleotide sequence of the crRNA is a sequence 8. Based on a CRISPR-Cas13a nucleic acid detection technology, the invention finally provides an RAA amplification primer pair for hepatitis delta virus RNA detection and specific crRNA targeting a target sequence, and the crRNA can realize high-sensitivity and high-specificity detection of hepatitis delta virus RNA by activating Cas13a, and has important application value in the field of detection and identification of hepatitis delta virus.
Owner:BEIJING YOUAN HOSPITAL CAPITAL MEDICAL UNIV

A colorimetric aptasensor based on single-atom nanoszyme and self-screening aptamer for ultrasensitive detection of tomato mosaic virus and a preparation method and application thereof

The present application relates to a kind of based on monatomic nanozyme and self-selection aptamer for super-sensitivity detection of tomato mosaic virus colorimetric aptamer sensor and its preparation method and application, belong to electrochemistry and biological detection technical field.The present application utilizes the complex of monatomic nanozyme FeCo-NC and aptamer 1 for ToMV and the microwell plate coated with aptamer 2 for ToMV to constitute the colorimetric aptamer sensor for super-sensitivity detection of tomato mosaic virus, by combining the excellent catalytic performance of FeCo-NC with colorimetric detection system, it is first to realize that electrochemical biosensor is used in the detection of tomato mosaic virus, by verification, the sensing strategy successfully realizes the high sensitivity, high specificity visual detection of tomato mosaic virus.
Owner:INSPECTION & QUARANTINE TECH CENT SHANDONG ENTRY EXIT INSPECTION & QUARANTINE BUREAU

Flexible pressure sensor based on magnetic field and preparation method thereof

The invention provides a flexible pressure sensor based on a magnetic field, and a preparation method and a detection method thereof. The flexible pressure sensor based on the magnetic field comprises a gradient magnetoelastomer, a flexible support body, a hard isolation layer and a Hall magnetic sensor, wherein the gradient magnetoelastic body is arranged on the upper side of the flexible supporting body, the hard isolation layer is arranged on the lower side of the flexible supporting body, and the Hall magnetic sensor is arranged on the hard isolation layer. According to the flexible pressure sensor based on the magnetic field and the preparation method and the detection method of the flexible pressure sensor, the problem that an existing flexible pressure sensor based on the magnetic field does not have high sensitivity and wide range at the same time can be solved.
Owner:NINGBO INST OF MATERIALS TECH & ENG CHINESE ACAD OF SCI

Multi-band radio frequency communication signal quality dynamic optimization method and intelligent water meter

PendingCN122373145AOvercome Response Lagavoid lossMulti bandSignal quality
The present application relates to a multi-band radio frequency communication signal quality dynamic optimization method and an intelligent water meter. In view of the problem that the risk of water meter communication frequency band interruption is difficult to predict in advance in complex environment, a high sensitivity MEMS accelerometer integrated with a master control chip is used to collect three-dimensional micro-vibration signals of the water meter shell through low sampling rate, combined with time-frequency joint analysis to extract vibration modal characteristics, a graph neural network model is used to associate vibration state with radio frequency channel quality index, and real-time prediction of deterioration risk probability is realized. According to the environmental dynamic disturbance factor, the threshold value is adjusted and determined, combined with the radio frequency index step deterioration monitoring, the intelligent communication frequency band switching and context caching are triggered. The newly added vibration and radio frequency data are used for model adaptive optimization. The scheme can predict the channel interruption risk in advance, effectively improve the communication stability and adaptability of the intelligent water meter.
Owner:GUANGNUO (YANGGU) ELECTRONIC TECH CO LTD

Rapid and high-sensitivity mycobacterium tuberculosis drug-resistant strain identification and Raman quantitative analysis method

The invention discloses a rapid and high-sensitivity mycobacterium tuberculosis drug-resistant strain identification and Raman quantitative analysis method, which comprises the following steps of: firstly, constructing a semiconductor surface enhanced Raman substrate with high stability and high enhancement factors by adopting a self-assembly method to amplify a Raman signal of a signal molecule to be detected, and providing high sensitivity for analysis and detection; secondly, designing and synthesizing a plurality of mycobacterium tuberculosis nucleic acid recognition units with single base recognition capability according to mutation sites of key drug-resistant genes of the binding bacilli; appropriate Raman signal molecules and internal reference analysis are selected, a high-selectivity and high-sensitivity enzyme-free nucleic acid amplification process-free rapid mycobacterium tuberculosis drug-resistant gene Raman analysis probe is constructed, and a brand new mycobacterium tuberculosis drug-resistant strain identification and Raman quantitative analysis chip and method are constructed through spatial arrangement design. And finally, normal-temperature long-term preservation of the analysis reagent, low-cost rapid typing of common binding bacterium drug-resistant strains, and high-sensitivity and high-selectivity quantitative analysis detection are realized.
Owner:EAST CHINA NORMAL UNIV

Voice recognition method based on flexible optical fiber coupler, controller and storage medium

The invention relates to the technical field of voice recognition, in particular to a voice recognition method based on a flexible optical fiber coupler, a controller and a storage medium, and the voice recognition method comprises the steps: obtaining an original voice signal, and carrying out the feature extraction of the original voice signal, and obtaining text data corresponding to the original voice signal; preprocessing the text data to obtain a first spectrum image corresponding to the text data; performing regularization processing on the first frequency spectrum image to obtain a second frequency spectrum image; and inputting the second frequency spectrum image into a Resnet deep learning model for feature extraction and prediction classification processing to obtain a sound analysis result corresponding to the second frequency spectrum image. According to the invention, the sensitivity of acquiring the sound signal is improved, the accuracy of the sound signal recognition result is improved, and the user experience is improved.
Owner:WUYI UNIV