1138results about How to "Accurate imaging" patented technology

A miniature surgical robot and a method for using it are disclosed. The miniature surgical robot attaches directly with the bone of a patient. Two-dimensional X-ray images of the robot on the bone are registered with three-dimensional images of the bone. This locates the robot precisely on the bone of the patient. The robot is then directed to pre-operative determined positions based on a pre-operative plan by the surgeon. The robot then moves to the requested surgical site and aligns a sleeve through which the surgeon can insert a surgical tool.

This invention provides an imaging optical lens assembly including: in order from an object side toward an image side: a first lens with positive refractive power and having a convex object-side surface, a second lens with negative refractive power and having a convex object-side surface and a concave image-side surface, a third lens with positive refractive power and having a concave object-side surface and a convex image-side surface, a fourth lens with negative refractive power and having a concave image-side surface, the object-side and image-side surfaces being aspheric, and a fifth lens having a concave image-side surface, the object-side and image-side surfaces being aspheric. The imaging optical lens assembly further comprises an aperture stop, disposed between an imaged object and the second lens, and an electronic sensor, disposed at the image plane for image formation.

The present invention relates to systems and methods for localized delivery of heat, useful for localized imaging and treatment of a biological material. The systems and methods of the invention can be utilized for localized treatment of cancer, inflammation or other disorders involving over proliferation of tissue, and for tissue repair. The method comprises exposing nanoparticles to electromagnetic radiation under conditions wherein the nanoparticles generate microbubbles which emit heat when exposed to ultrasonic radiation.

An apparatus and the method of its operation for rapid prototyping of a three-dimensional object which includes a radiant energy source of a wide beam of radiant energy of suitable intensity and wavelength for curing a layer of photo-curable resin contained in an open vat, a spatial light modulator (SLM) having an array of pixel elements which are individually digitally controllable by a computer, for modulating the radiant energy beam projected from the radiant energy source on a pixel by pixel basis, to form a series of time sequential images of the cross-sectional laminae of the object, an optical system for focusing each image formed by the SLM, one at a time, onto successive layers of photo-curable resin for predetermined exposure times to thereby form stacked laminae of cured resin, each lamina of cured resin being in the shape of a different one of the cross-sectional laminae, and a piston support for lowering each lamina of cured resin after it is formed by the SLM and for depositing a layer of resin corresponding to the thickness of one cross sectional lamina of the three-dimensional object before the step of projecting a new image by the SLM. The SLM, the piston support for lowering, and the optical system operate repeatedly and sequentially until a complete copy of the object is thereby produced.

Enhanced accuracy finger position and motion sensors devices, algorithms, and methods are disclosed that can be used in a variety of different applications. The sensors can be used in conjunction with partial fingerprint imagers to produce improved fingerprint scanners. The finger motion sensors may also be used (either with or without a partial fingerprint imager) to control electronic devices. When several of these finger motion and position sensors are aligned in different directions, finger motion over a two dimensional surface may be detected. This creates a finger controlled “mouse” computer input device. Motion of a finger along the surface of such sensors may allow a user to control the movement of an indicator on a display screen, and control a microprocessor device. Such techniques are particularly useful for small space constrained devices, such as cell phones, smart cards, music players, portable computers, personal digital accessories, and the like.

The invention is directed to a method and an arrangement for high-resolution microscopic imaging in laser endoscopy based on laser-induced object reaction radiation and for performing microscopic cuts in biological tissue. In using multiphoton processes for endoscopic applications in biological materials with an accuracy of under one millimeter, radiation of a pulsed femtosecond laser is focused into an object by means of a transmission focusing optics unit comprising a transmission system and miniature focusing optics having a high numerical aperture greater than 0.55 to trigger a local object reaction radiation in the micrometer to nanometer range, and the distal end of the transmission focusing optics unit is moved in at least two dimensions for highly spatially resolved scanning of the object and for transmitting object reaction radiation which is scanned in a locally progressive manner to an image-generating system with a photon detector. In an other embodiment the femtosecond laser radiation is energy enhanced is applied to the same transmission focusing optics unit to perform microendoscopic surgery in biological tissue.

A new way of mixing instrumental and digital means is described for the general field of wave front sensing. The present invention describes the use, the definition and the utility of digital operators, called digital wave front operators (DWFO) or digital lenses (DL), specifically designed for the digital processing of wave fronts defined in amplitude and phase. DWFO are of particular interest for correcting undesired wave front deformations induced by instrumental defects or experimental errors. DWFO may be defined using a mathematical model, e.g. a polynomial function, which involves coefficients. The present invention describes automated and semi-automated procedures for calibrating or adjusting the values of these coefficients. These procedures are based on the fitting of mathematical models on reference data extracted from specific regions of a wave front called reference areas, which are characterized by the fact that specimen contributions are a priori known in reference areas. For example, reference areas can be defined in regions where flat surfaces of a specimen produce a constant phase function. The present invention describes also how DWFO can be defined by extracting reference data along one-dimensional (1D) profiles. DWFO can also be defined in order to obtain a flattened representation of non-flat area of a specimen. Several DWFO or DL can be combined, possibly in addition with procedures for calculating numerically the propagation of wave fronts. A DWFO may also be defined experimentally, e.g. by calibration procedures using reference specimens. A method for generating a DWFO by filtering in the Fourier plane is also described. All wave front sensing techniques may benefit from the present invention. The case of a wave front sensor based on digital holography, e.g. a digital holographic microscope (DHM), is described in more details. The use of DWFO improves the performance, in particular speed and precision, and the ease of use of instruments for wave front sensing. The use of DWFO results in instrumental simplifications, costs reductions, and enlarged the field of applications. The present invention defines a new technique for imaging and metrology with a large field of applications in material and life sciences, for research and industrial applications.

Enhanced accuracy finger position and motion sensors devices, algorithms, and methods are disclosed that can be used in a variety of different applications. The sensors can be used in conjunction with partial fingerprint imagers to produce improved fingerprint scanners. The finger motion sensors may also be used (either with or without a partial fingerprint imager) to produce highly accurate fingerprint images as well as to control electronic devices. Here improved signal analysis algorithms and methods are disclosed that enable finger position to be determined with higher levels of accuracy as the finger is swiped over finger position sensing arrays. These algorithms are particularly useful for deep finger penetrating radio frequency (RF) based sensing arrays.

The present invention relates generally to the field of high content screening of particles, e.g., cells in a flow cytometric system. In particular, the present invention relates to devices, methods and systems to obtain line-scan images of particles, e.g., cells, of a plurality of different samples simultaneously, where the line-scan images can be used to identify cells based on at least one of a variety of phenotypic characteristics such as shape, asymmetry, and intracellular information for cell sorting and selection. In some embodiments, the line-scan images are obtained as the particles, e.g., cells, in a plurality of different samples flow through a plurality of microchannels, reducing the need and time for focusing of the image detection system. In some embodiments, the laser spot size has a small spatial resolution for rapid capturing of images of cells. In some embodiments, the laser spot size has a larger spatial resolution for imaging of larger particles or cells, e.g., rare cells in a sample. In some embodiments, the devices, methods and systems are automated for a high-throughput, high content screening of particles such as cells in a plurality of samples.

According to an aspect of the invention, since two range images (first and second range images) are individually generated by a first range image generating device and a second range image generating device by different methods, and one range image (a third range image) is generated on the basis of those range images, highly accurate range images are generated. Furthermore, as the first range image generating device and the second range image generating device commonly use image sensors, the increase in hardware size and in cost due to the use of two devices for generating range images can be restrained.

A portable, lightweight digital imaging device uses a slit scanning arrangement to obtain an image of the eye, in particular the retina. In at least one embodiment, a digital retinal imaging device includes an illumination source operable to produce a source beam, wherein the source beam defines an illumination pathway, a scanning mechanism operable to cause a scanning motion of the illumination pathway in one dimension with respect to a target, an optical element situated within the illumination pathway, the optical element operable to focus the illumination pathway into an illumination slit at a plane conjugate to the target, wherein the illumination slit is slit shaped, a first two dimensional detector array operable to detect illumination returning from the target and acquire one or more data sets from the detected illumination, wherein the returning illumination defines a detection pathway, and a shaping mechanism positioned within the illumination pathway, wherein the shaping mechanism shapes the source beam into at least one arc at a plane conjugate to the pupil. In at least one exemplary embodiment, the digital retinal imaging device is operable to minimize at least one aberration from the optical element or an unwanted reflection from the target or a reflection from a device.

This invention provides an infrared illuminator and camera system for imaging of auto vehicle license plates. The system works in ambient light conditions, ranging from bright sunlight, to dim light, to dark, to zero ambient light. It yields high-contrast imaging of the letters and numbers on retro-reflective license plates. The images of the license letter and number combinations can be read manually by a remote operator. They can be converted to text format with optical character recognition computer hardware and software. The text data can then be compared to data files listing license numbers to provide further data about the owner of a licensed vehicle. A decision can be made quickly about whether to allow a vehicle to proceed through a gate, or whether to take other action. The system uses a mono camera that is enhanced for infrared sensitivity and combined with a high power infrared illuminator to maximize range at night, and with shutter speeds set up to capture clear license plate pictures even with fast moving vehicles and even with their headlights on and interfering with human observation of the license plates. Optical filtering to pass infrared in the range of the illuminator and to reduce light outside this range, combines with a lens set up, to avoid vertical smear and sensor overload caused by headlights at night and by highlight reflected glare from the sun in daytime.

An image taking apparatus includes: a photoelectric conversion unit including a plurality of photoelectric conversion elements, the photoelectric conversion elements disposed in a two-dimensional matrix, the photoelectric conversion elements converting received light into electric charge and accumulating the electric charge; an image sensor having a function of controlling an exposure time of each of the photoelectric conversion elements of the photoelectric conversion unit on a line-by-line basis; an area division unit for logically dividing the photoelectric conversion unit into an N number of uniform areas on the basis of information related to a taken image of a subject, each of the uniform areas including a line having some of the photoelectric conversion elements, N being a natural number of two or more; an interlaced scanning unit for scanning the photoelectric conversion elements in the first to N-th areas by M lines starting with a predetermined line in a predetermined area of the first to N-th areas while changing an area to be scanned to another area in a predetermined order each time the M lines are scanned, M being a natural number of one or more; and a pixel signal reading unit for reading, from each of the photoelectric conversion elements scanned by the interlaced scanning unit, a pixel signal including an electric signal corresponding to an amount of electric charge accumulated in each photoelectric conversion element.

Methods and systems for intensity/brightness matching of a plurality of radiographic images. Software can be used to provide various stitching and blending methods to join first and second images into a composite, larger image before or after the intensity/brightness of the radiographic images are modified.

Echogenic devices, and methods of making and using such devices, are disclosed. In one aspect, the devices include a porous polymeric material that is preparable by extracting a phase separated composition. In another aspect, the echogenic devices include a polymeric composition having porous particles therein. Preferably the devices are medical devices.

A non-transitory machine readable medium that a computer program for performing a color balance operation on color values of an image represented in a color space is described. The computer program receives a selection of a location on the image that includes several pixels. Each of the several pixels of the image includes a set of color values. Based on a set of color values of a set of pixels that corresponds to the selected location of the image, the computer program identifies a set of parameters for generating a color space transform that modifies the color space. The computer program then uses the color space transform to perform a color balance operation on the image.

Pages of books are copied without distortion due to curvature of the page near the book binding or the distortion in a copied page is corrected using the spacing of equidistant bars on tape strips applied to the top and bottom edges of a page before copying. The tape is preferably transparent and rather narrow and easily attached to a page to be copied. The first step in the distortion correction procedure is to locate the bars at the top and bottom of the page. The distortion of the spacing between the imaged bars is computed based on the known distance between the equidistant bars. The computed distortion of the spacing is then input to a distortion correction algorithm. The output of the distortion correction algorithm generates a corrected image. This image may also optionally delete the bars so that they are not printed in the copy. The corrected image is then copied.

A diagnostic and therapeutic contact lens is provided for use with biomicroscopes for the examination and treatment of structures of the eye. The lens comprises a contacting surface adapted for placement on the cornea of an eye, two reflecting surfaces, and a refracting surface. A light ray emanating from the structure of the eye enters the lens and contributes to the formation of a correctly oriented real image. The light ray is reflected in an ordered sequence of reflections, first as a negative reflection in a posterior direction from an anterior reflecting surface and next as a positive reflection in an anterior direction from a posterior reflecting surface. The light ray contributes to forming the image of the structure of the eye either anterior to the lens or within the lens and proceeds along a pathway to the objective lens of the biomicroscope used for stereoscopic viewing and image scanning.