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1440 results about "Microscopic image" patented technology

Microchip appearance defect detection method based on convolutional neural network

The invention relates to a microchip appearance defect detection method based on a convolutional neural network. The microchip appearance defect detection method comprises the following steps: acquiring a high-resolution microscopic image and carrying out adaptive brightness equalization processing; labeling defect features in the pre-processed image by adopting a layered labeling strategy, and dividing defects into a surface deformation class and a material anomaly class by coarse-grained classification labeling; a double-branch lightweight convolutional neural network model is constructed based on the annotation data, a first branch extracts global semantic features, and a second branch extracts local detail features. In the model training, a defect sensitivity loss function is adopted for optimization, and defect area attention, edge preservation and category balance loss items are included, so that the small-size defect detection capability and the boundary positioning precision are improved, and the problem of sample imbalance is solved. And finally, a detection result including defect types, position coordinates and confidence scores is generated by inputting a to-be-detected preprocessed microscopic image, and the defect detection performance with high precision and strong pertinence is achieved.
Owner:JIANGSU MINGYIXIN INTELLIGENT EQUIPMENT CO LTD

Ceramic supply chain quality traceability data management system based on block chain

The invention relates to the technical field of data processing, in particular to a ceramic supply chain quality traceability data management system based on a block chain, which comprises a data acquisition and processing module, a dynamic identifier generation module, an identifier embedding control module, a cross-chain data synchronization module, a multi-modal verification module and a redundancy recovery module. The data acquisition and processing module integrates firing temperature, forming pressure parameters and microscopic image data through Internet of Things equipment and edge computing nodes to generate a structured data set, the system integrated resource scheduling module optimizes node computing resource allocation, and anti-quantum encryption and IPFS distributed storage guarantee data security. And the terminal equipment integration module simplifies the multi-modal data acquisition process, and finally collaborative optimization of the ceramic quality tracing reliability, the operation efficiency and the artistic integrity is realized.
Owner:SHENYANG MOSEN TECH CO LTD

Improved convolution integral neural network model for leukocyte calculation

The invention discloses an improved convolution neural network model for leukocyte calculation, and relates to the field of artificial intelligence and medical image processing. Aiming at the problems of inaccurate feature extraction, strong background noise interference and insufficient multi-scale feature fusion in a traditional leukocyte calculation method, the model realizes fine processing and feature enhancement of a medical image through a multi-level modular design; the image preprocessing module is used for completing white blood cell positioning and image adaptive division and enhancement; multi-scale edge, texture and gray features are fused by means of an image feature extraction module, and a composite feature vector is constructed; through multi-scale convolution, a double-layer attention mechanism and convolution layer calculation of the improved convolution neural network model module, precise focusing of white blood cell contours and cell nucleus features, background noise suppression and calculation efficiency optimization are realized; and finally, a calculation result is output through a visual terminal, so that the accuracy and robustness of leukocyte counting are remarkably improved, and efficient technical support is provided for medical microscopic image analysis.
Owner:北京轻盈医院管理有限公司

Small sample plankton image enhancement recognition method and small sample plankton image model building method

The invention provides a small sample plankton image enhancement recognition method and a small sample plankton image model building method, and belongs to the technical field of underwater image enhancement. The method comprises the following steps: firstly, acquiring and sorting plankton microscopic image data, and constructing a normalized data set; secondly, designing a small sample plankton image enhancement recognition model based on a feature map reconstruction technology, performing feature extraction on the image by adopting a deep convolutional neural network, generating an intermediate layer feature map, and realizing category discrimination in combination with a feature map reconstruction mechanism; the model fuses multiple key designs oriented to cross-domain adaptation and structure perception, the distribution difference between different data domains is relieved, and the characterization capability of the model on the complex morphological structure of plankton is also remarkably improved; and finally, performing end-to-end training and optimization on the model under a meta-learning framework to obtain an optimal model. Experimental results show that the method shows excellent classification performance on a plurality of plankton data sets, and high-precision recognition can be achieved under the condition that the number of samples is limited.
Owner:OCEAN UNIV OF CHINA

Kit raw material quality detection method based on multi-modal data fusion

The invention discloses a kit raw material quality detection method based on multi-modal data fusion, and relates to the technical field of automatic quality detection of chemical reagent raw materials. Comprising the following steps: S1, synchronously acquiring spectral data, microscopic image data and chemical detection data of a kit raw material through a spectral sensor, microscopic imaging equipment and a chemical sensor; s2, inputting the multi-modal data into a self-adaptive spatial-temporal feature calibration network, and analyzing local detail features and global time sequence features of the modal data through a multi-scale spatial-temporal feature extraction module; according to the kit raw material quality detection method based on multi-modal data fusion, by constructing a collaborative fusion system of an adaptive spatial-temporal characteristic calibration network and a layered information entropy screening mechanism, the core technical problems of misalignment of multi-modal data dynamic alignment and redundant interference accumulation are solved.
Owner:JILIN UNIVERSITY

Deep learning-based microscopic image seamless splicing and enhanced reconstruction method

The invention discloses a microscopic image seamless splicing and enhanced reconstruction method based on deep learning, and the method comprises the following steps: S1, collecting a plurality of original images with overlapped regions, and recording the spatial position information and imaging parameters of the original images; s2, preprocessing the original image to generate a standardized image sequence; s3, inputting the standardized image into a structure perception feature extraction network, and extracting a feature map fusing textures and structures; s4, inputting the feature image and the original image into an image registration module; s5, inputting the registration image into the boundary attention splicing network; s6, inputting the seamless image into the residual hierarchy reconstruction network, and enhancing image details through hole convolution and multi-scale branches; s7, image quality evaluation is executed, and the structural similarity, the signal-to-noise ratio and the edge retention rate are calculated; and S8, constructing a training set and carrying out end-to-end training optimization based on a joint loss function. According to the method, a multi-module deep network is fused, and seamless splicing and high-quality enhanced reconstruction of microscopic images are realized.
Owner:DINGCHANG MEDICAL TECHNOLOGY (SUZHOU) CO LTD

Pathological feature recognition and negative elimination method based on microscopic imaging

The invention discloses a pathological feature recognition and negative elimination method based on microscopic imaging. The method comprises the following steps: S1, collecting a pathological section image and digitally generating original microscopic image data; s2, preprocessing the original microscopic image; s3, constructing a pathological image recognition network fusing converter coding and a gating dynamic receptive field mechanism, and outputting pathological feature vectors; s4, performing context modeling through an attention guidance and category perception decoder, and outputting an image classification result; s5, constructing a discriminant boundary separation model based on positive and negative sample embedding, and performing negative exclusion judgment; s6, performing confidence coefficient weighted evaluation in combination with the uncertainty and the boundary distance, setting a dynamic threshold value, and screening out low-credibility samples; and S7, coding the classification result and the negative label into structured data, and sending the structured data to a diagnosis auxiliary system. According to the method, multi-scale modeling and a negative screening mechanism are fused, and intelligent recognition and credible diagnosis output of the pathological image are realized.
Owner:DINGCHANG MEDICAL TECHNOLOGY (SUZHOU) CO LTD

Tomato disease diagnosis method based on multi-modal data analysis

The invention relates to the technical field of intelligent agricultural equipment, in particular to a tomato disease diagnosis method based on multi-modal data analysis, which comprises the following steps of: 1, synchronously acquiring and preprocessing multi-modal data, synchronously triggering a hyperspectral imaging device and a microscopic camera, respectively acquiring a plant canopy hyperspectral image and a stem microscopic image, and acquiring a plant canopy hyperspectral image and a stem microscopic image; meanwhile, temperature, conductivity and dissolved oxygen environment parameters are continuously collected in the root zone; 2, self-adaptive feature extraction and fusion in the growth stage are carried out, reflectivity correction and leaf segmentation are carried out on the hyperspectral image, and leaf surface spectrum curve features are extracted; step 3, hybrid model construction and space-time analysis: constructing a hybrid model comprising spectrum, microscopy and environment analysis networks, and dynamically adjusting each network weight through a gating network; and 4, generating a disease decision. The method can realize accurate, efficient and real-time tomato disease diagnosis, has high practical value, and can effectively improve the disease prevention and control capability in agricultural production.
Owner:CHAOHU LUOXIANG AGRICULTURAL DEVELOPMENT CO LTD

Phytoplankton microscopic image classification model construction method

The invention discloses a phytoplankton microscopic image classification model construction method, and belongs to the field of intelligent detection. For the problems of unstable microscopic image quality and small difference between phytoplankton classes, a double-branch ResNeXtViT model is provided: a ResNeXt branch enhances the texture feature extraction capability through a wavelet convolution attention module, and improves the adaptability to irregular shapes in combination with an adaptive convolution module; a Transform branch is used for capturing global context information; the feature fusion module integrates local details and a global structure. A combined data enhancement strategy including noise addition and color migration is adopted, and a joint loss function is designed to optimize intra-class compactness and local discrimination capability. Experiments show that the accuracy of the method on a Chaohu lake phytoplankton data set reaches 94.11%, which is superior to that of ResNet, ViT and other models, and the method can be deployed to an intelligent analyzer to realize rapid water quality monitoring.
Owner:Hefei Comprehensive Science Center Environmental Research Institute

Titanium alloy microscopic structure identification method and system based on deep learning and medium

The invention discloses a titanium alloy microstructure recognition method and system based on deep learning and a medium, and belongs to the technical field of image recognition, and the method comprises the steps: carrying out the serialization processing of a preprocessed microscopic image based on a trained image recognition model, inputting the serialized microscopic image into a Transformer encoder, and carrying out the recognition of a titanium alloy microstructure. And the features extracted by the Transform encoder are respectively output to a pixel-level phase classification branch and an image-level tissue classification branch, and phase classification and tissue classification are correspondingly carried out. The tissue type probability output by the image-level tissue classification branch is used as a gating signal, and the corresponding segmentation channel of the pixel-level phase classification branch is correspondingly enhanced or inhibited; based on an interactive attention mechanism, the classification semantics of the image-level organization classification branches are reversely projected to the middle layer of the segmentation branches of the pixel-level classification branches. According to the method, the microscopic structure analysis efficiency and the standardization degree are remarkably improved, and good practicability is achieved.
Owner:SHANGHAI JIAOTONG UNIV

Automobile hot galvanizing process parameter optimization method and system based on artificial intelligence

The invention relates to the technical field of hot galvanizing, and discloses an automobile hot galvanizing process parameter optimization method and system based on artificial intelligence, and the method comprises the steps: carrying out window division processing on initial cooling parameters, constructing a cooling rate matrix, and finely depicting heat exchange states of different cooling sections; the problem of insufficient cooling control precision under different cooling speed alternating conditions is solved, a microscopic image is combined to extract the grain main axis direction, calculate the mean value and range of included angles, generate a consistency index set and quantitatively describe the dispersion problem in the grain growth direction, the cooling speed and the consistency index are jointly matched, and a cooling speed structure offset matrix is constructed. The method comprises the following steps: identifying a space mutation region, accurately positioning abnormal coarse or abnormal arrangement positions of crystal grains, and finally screening target cooling parameters according to a cooling index value corresponding to an abnormal region to realize local adjustment of a cooling process, thereby reducing the abnormal growth rate of the crystal grains and improving the direction consistency of the crystal grains.
Owner:HUNAN INSTITUTE OF ENGINEERING

Method and system for digital staining of microscopy images using deep learning

A deep learning-based digital / virtual staining method and system enables the creation of digitally / virtually-stained microscopic images from label or stain-free samples. In one embodiment, the method of generates digitally / virtually-stained microscope images of label-free or unstained samples using fluorescence lifetime (FLIM) image(s) of the sample(s) using a fluorescence microscope. In another embodiment, a digital / virtual autofocusing method is provided that uses machine learning to generate a microscope image with improved focus using a trained, deep neural network. In another embodiment, a trained deep neural network generates digitally / virtually stained microscopic images of a label-free or unstained sample obtained with a microscope having multiple different stains. The multiple stains in the output image or sub-regions thereof are substantially equivalent to the corresponding microscopic images or image sub-regions of the same sample that has been histochemically stained.
Owner:RGT UNIV OF CALIFORNIA

Processing surface quality detection system and method based on microscopic image

The invention relates to the field of intelligent detection, and provides a machined surface quality detection system and method based on microscopic image.The method comprises the steps that firstly, a multi-focal-plane image sequence of a target product sample is obtained, and a full-clear image of the target product sample is generated through super-depth-of-field image synthesis; then preprocessing and calibrating the full-clear image to obtain a standardized image of the sample, then analyzing and measuring the surface characteristics of the sample based on the standardized image to generate structured data of the product processing surface quality, and finally determining the quality of the product according to a preset quality standard. And processing the structured data to form a product processing surface quality evaluation report. In this way, the comprehensiveness and accuracy of quality detection of the machined surface can be effectively improved.
Owner:SHANGHAI MAGIC PHOTOELECTRIC TECH CO LTD

Defect identification method and system for molybdenum-rhenium alloy pipe fitting based on high-definition microscopic image

The invention discloses a molybdenum-rhenium alloy pipe fitting defect identification method and system based on a high-definition microscopic image. The method comprises the following operation steps that high-definition microscopic equipment is used for collecting the high-definition image of a molybdenum-rhenium alloy pipe fitting; preprocessing the high-definition image of the molybdenum-rhenium alloy pipe fitting to obtain a molybdenum-rhenium image to be detected; performing execution processing of a region growing algorithm on the molybdenum-rhenium image to be detected to obtain a defect region to be detected; performing defect identification on the to-be-detected defect area to obtain type defects; and judging the defect problem of the molybdenum-rhenium alloy pipe fitting according to the type defect.
Owner:LUOYANG SIFON ELECTRONICS

Noninvasive sperm cell death and viability detection method

The invention relates to the technical field of biomedical detection, and discloses a non-invasive sperm cell death and viability detection method, which utilizes a bright field image and a fluorescence image to train a fluorescence-assisted bright field attention network, introduces a fluorescence attention guidance module to provide guidance for training of a Transformer encoder, and realizes non-invasive sperm cell death and viability detection through priori knowledge of the fluorescence image. By means of the method, the model can be quickly focused on key features displayed in the fluorescent highlight area, the situation that training resources are consumed on a large amount of irrelevant information is avoided, convergence is accelerated, the model training time is shortened, meanwhile, the detection precision is improved, and then a more accurate and efficient sperm cell death and activity detection model is obtained. And during actual detection, the sperm cell death and viability detection can be realized only by collecting a microscopic image, pre-processing the microscopic image and inputting the preprocessed microscopic image into the model without dyeing a sperm sample, so that the damage of a traditional detection method to sperms is avoided, the non-invasive detection of the sperm cell death and viability is realized, and the method is more suitable for clinical detection.
Owner:SUZHOU BOUNDLESS MEDICAL TECH CO LTD

Floating algae flow type microimaging sheath fluid focusing micro-fluidic chip device and floating algae flow type microimaging sheath fluid focusing micro-fluidic chip system

The invention discloses a floating algae flow type microimaging sheath fluid focusing micro-fluidic chip device and system, and belongs to the technical field of micro-fluidic control. According to the device, the three-channel sheath fluid flow chip design is adopted, a large-channel inlet structure is combined to avoid algae cell blockage, and a sheath flow focusing technology is utilized to compress a sample flow to the center of a channel and limit the sample flow within the field depth range of a microscope objective to obtain a clear image. The arc-shaped structure of the sample channel reduces laminar flow disturbance, and a four-side transparent observation area supports panoramic depth imaging. The system comprises a microscopic imaging module, a fluid driving module and a sheath liquid flow chip module, a flow rate ratio of sheath liquid flow to sample flow is accurately controlled through a dual-channel liquid flow driving injection pump, and stable imaging within the depth of field of an objective lens is realized by combining a manual focusing platform. Experimental verification shows that the system can effectively compress sample flow to 21m nuclear flow diameter, imaging of floating algae such as chlorella, scenedesmus quadricauda and the like is clear, and the contradiction between flux and imaging quality of a traditional micro-fluidic chip is solved.
Owner:HEFEI INSTITUTE OF PHYSICAL SCIENCE CHINESE ACADEMY OF SCIENCES

Intelligent algae analysis method and system

The invention provides an intelligent algae analysis method and system, and the method comprises the steps: S1, collecting a microscopic image in a microfluidic channel through a flow analyzer based on a target water body; s2, accurately marking the category, the position and the boundary characteristics of the microalgae in the microscopic image by using a marking tool supporting image segmentation and classification in combination with corresponding microalgae classification data; s3, based on the pre-training weight of the Ground SAM, performing fine tuning optimization on the model by using a transfer learning method so as to adapt to microalgae detection; s4, preprocessing the microscopic image acquired in the step S1; s5, for the preprocessed microscopic image, on the basis of the training model in the step S3, realizing target detection and segmentation of microalgae in the microscopic image by using Ground SAM; and S6, counting the types and volumes of the microalgae, identifying the types of the algae, and calculating the density of the algae. Under the support of the flow analyzer, each microalgae cell is accurately detected and counted, so that more detailed algae density data is obtained.
Owner:INST OF AQUATIC LIFE ACAD SINICA

Super-resolution fluorescence lifetime microscopic imaging method and system based on pixel relocation

The invention relates to a super-resolution fluorescence lifetime microscopic imaging method and system based on pixel relocation. The method comprises the following steps: S1, carrying out multi-focus parallel scanning on a sample by using an acousto-optic deflector; s2, synchronously collecting a fluorescence intensity image and fluorescence lifetime data through an area array detector and a point detector; and S3, carrying out super-resolution reconstruction on the fluorescence intensity image based on a pixel relocation algorithm, and mapping fluorescence lifetime data to a reconstructed image to generate a super-resolution fluorescence lifetime microscopic image. According to the invention, an AOD is adopted to replace a scanning galvanometer in a traditional TCSPC-FLIM imaging system as a light beam scanner; addressing scanning of AOD, image acquisition of EMCCD and life data acquisition of PMT and TCSPC cards are closely linked by combining well-designed multiple paths of synchronizing signals, and fluorescence life data are distributed to each dot matrix through a later data processing method, so that organic combination of super-resolution and FLIM can be realized without complicated equipment, and SR-FLIM images of samples are obtained.
Owner:SHENZHEN UNIV

Multi-path convolutional neural network-based palletizing robot path planning method

The invention discloses a path planning method for a palletizing robot based on a multi-path convolutional neural network, and relates to the technical field of convolutional neural networks, and the method comprises the steps: employing the three-source data of a quality inspection report image, a damaged video and a microscopic image, extracting features through a parallel convolutional neural network, generating a dynamic maximum curvature constraint value after the fusion, and obtaining the path planning of the palletizing robot. And self-adaptive path planning of material characteristics is realized. And nodes conforming to curvature constraint are screened based on a probability route map (PRM) to generate a track, and the vibration spectrum energy of the mechanical arm is monitored in real time. When vibration exceeds a dynamic safety threshold value, subsequent path constraint is tightened in real time through a curvature penalty factor, and the damage risk is reduced by 90%; a closed loop of material analysis, path generation, vibration feedback and parameter correction is established, and balance of safety and efficiency is achieved in a high-speed stacking scene.
Owner:JINING UNIV

Microscopic image representation method based on dynamic pluggable mask self-supervision encoder

The invention provides a microscopic image representation method based on a dynamic pluggable mask self-supervision encoder. The microscopic image representation method comprises the following steps: step 1, establishing a network based on the dynamic pluggable mask self-supervision encoder and an MAE decoder; 2, constructing a loss function to train the network, and carrying out the combined optimization of image reconstruction and classification; step 3, using a pre-training dynamic pluggable mask self-supervision encoder to extract deep feature representation of the microscopic image; and further connecting a decoder of a downstream task, and carrying out mineral microscopic image super-resolution reconstruction, inclusion automatic analysis, intelligent diamond cleanliness rating and general cell segmentation. According to the method, the feature extraction quality of the field with the data volume disadvantage is improved through the pluggable module, and the problem that most categories of cross-field data sets are unbalanced is effectively solved. Meanwhile, compared with the addition of branches, the pluggable module reduces the extra calculation overhead brought by the addition of a structure by 50%, and endows the model with extremely strong domain mobility.
Owner:BEIHANG UNIV

Micro-fluidic chip imaging positioning device

The utility model discloses a micro-fluidic chip imaging positioning device, and belongs to the technical field of micro-fluidic chip positioning. According to the technical scheme, the system comprises a microcosmic illumination module, a microcosmic imaging module, a chip moving and macroscopic illumination module, a macroscopic imaging module and an optical path multiplexing module; the microscopic illumination module comprises a fly's-eye lens assembly, the fly's-eye lens assembly comprises two fly's-eye lenses, the optical axes of the two fly's-eye lenses are parallel to each other, and the focus of each lens array element in one fly's-eye lens coincides with the center of the lens array element at the corresponding position of the other fly's-eye lens. The micro-fluidic chip clamp is applied to the aspect of micro-fluidic chip imaging positioning, overcomes the defects caused by an existing micro-fluidic chip clamp, solves the technical problems of universality, automation and high precision of micro-fluidic chip positioning, and has the characteristics of rapidness, automation, high precision and universality.
Owner:QINGDAO SINGLE CELL BIOTECH CO LTD

A method for identifying clue cells in leucorrhea microscopic images

The present invention provides a method for identifying clue cells in a leucorrhea microscopic image, which belongs to the technical field of clue cell identification, and comprises: firstly, pre-processing the stained leucorrhea microscopic image, including graying, medical image enhancement and noise removal. Through spectral feature analysis, a feature space is constructed and adaptive threshold segmentation is adopted to extract the cell area, and then edge detection and morphological operations are performed to accurately extract the complete outline of the cell. The morphological feature parameters such as cell area, perimeter, roundness, grayscale mean and variance are innovatively calculated, and a feature discrimination equation group is established in combination with the spectral feature vector to realize accurate classification and identification of cells. The identification results are post-processed to remove noise interference and perform connected area analysis, the number and proportion of clue cells are counted, and annotated images are generated; and the iterative optimization of the data set verified by medical experts solves the technical problem that the consistency of the diagnosis results is poor due to the subjective experience differences of doctors.
Owner:AFFILIATED HOSPITAL OF WEIFANG MEDICAL UNIV

Parasite ovum microscopic image detection method and system based on polymorphic prior

The invention relates to the technical field of medical image processing and computer vision, in particular to a parasitic ovum microscopic image detection method and system based on polymorphic prior, and the method comprises the steps: obtaining a to-be-detected microscopic image, and carrying out the feature extraction of the to-be-detected microscopic image through a convolutional neural network, and obtaining an initial feature map; constructing a polymorphic convolution kernel library based on preset biological morphological characteristics of the parasitic ova; performing deep convolution and feature fusion operation on the initial feature map by using a polymorphic convolution kernel library to generate a space attention map; performing feature enhancement processing on the initial feature map by using the spatial attention map to obtain an enhanced feature map; and performing bounding box regression and category prediction on the enhanced feature map to obtain a parasitic ovum detection result. According to the method, morphological priori and attention mechanisms are introduced, so that the problems of egg form similarity, background interference and the like are solved, accurate and robust automatic detection is realized, and the clinical diagnosis efficiency is remarkably improved.
Owner:SHANGHAI INSTITUTE OF INFECTIOUS DISEASE & BIOSECURITY

Carbon fiber composite material microcrack image segmentation method based on two-stage super-resolution dynamic attention network

The invention provides a carbon fiber composite material microcrack image segmentation method based on a two-stage super-resolution dynamic attention network, and the method comprises the steps: collecting a microscopic image of a to-be-detected carbon fiber composite material, and carrying out the preprocessing of the image, so as to improve the discrimination between a crack and a background; scanning the preprocessed image by adopting a multi-scale sliding window, carrying out microcrack feature extraction in combination with morphological Top-hat transformation, and positioning a candidate region with microcracks; cutting an image corresponding to the candidate region into sub-images, inputting the sub-images into a pre-trained super-resolution reconstruction network, and amplifying the sub-images to 2-8 times of the original size to obtain a high-resolution candidate region image; inputting the super-resolution enhanced candidate region image into a pre-trained convolutional neural network model for pixel-level crack segmentation to obtain a segmentation result of cracks in the candidate region; and mapping the segmented micro-crack region back to an original image coordinate system, marking the position and shape of the crack on the original image, and outputting a final micro-crack segmentation result.
Owner:DALIAN MARITIME UNIVERSITY

Mineral oxygen element analysis method based on multi-mode LIBS

The invention discloses a multi-mode LIBS mineral oxygen element analysis method. The method comprises the following steps: firstly, preprocessing an LIBS spectrum, and then fusing the spectrum and a mineral microscopic image by using a deep learning model to carry out feature extraction and oxygen analysis. The core of the method is model training: shielding a spectrum, pairing the spectrum with a corresponding mineral image (positive samples and negative samples), and generating a fused spectrum-image representation by using mask reconstruction and comparative learning. The element content is predicted based on this representation, and the model is optimized according to the oxygen prediction results. According to the method, accurate, robust and interpretable quantitative analysis of the oxygen element in the complex mineral matrix can be realized.
Owner:LISEN OPTICS SHENZHEN CO LTD

Cell classification and function evaluation method and system based on nucleolus morphology

The invention relates to the field of cell classification, in particular to a cell classification and function evaluation method and system based on nucleolus morphology. The method provided by the invention comprises the following steps: S101, acquiring microscopic image data of a biological sample; s102, acquiring a first region of interest, a second region of interest and a third region of interest; s103, extracting kernel feature data; s104, carrying out first classification on cells in the biological sample; s105, carrying out second classification on the C-type cells in the biological sample; and S106, calculating the number and / or proportion of the A-type cells and the B-type cells in the biological sample so as to evaluate the functional state of the tissues or organs corresponding to the biological sample. The method can accurately and sensitively reflect and evaluate the functional state of the tissue or organ corresponding to the biological sample, and is especially suitable for the biological sample which is lack of a specific marker and has strong heterogeneity.
Owner:SHANGHAI JIAOTONG UNIV

Chromosome abnormality detection method based on image analysis

The invention belongs to the technical field of biomedical image processing and analysis, and particularly discloses a chromosome abnormality detection method based on image analysis, which comprises the following steps: obtaining a user chromosome microscopic image set and extracting a multi-modal feature data set for processing to obtain abnormal chromosome feature data of an abnormal tracking area; and performing collection processing to obtain an abnormal risk assessment index, performing correction in combination with abnormal identification coefficients of a plurality of historical similar abnormal samples to obtain an abnormal risk correction index, and performing assessment processing according to an obtained clinical detection data set corresponding to the abnormal tracking area in combination with genetic background feature data to obtain an abnormal tracking area genetic risk judgment index. And comparing the abnormal risk correction index with the abnormal risk correction index to obtain an abnormal evaluation matching degree coefficient, and verifying an abnormal evaluation result through threshold comparison, so that efficient identification and accurate evaluation of various complex chromosome abnormality types are realized, and comprehensive risk evaluation is performed in combination with genetic background information and clinical data to improve the reliability of a detection result.
Owner:山西省汾阳医院

Stem cell microscopic image feature extraction method and system

ActiveCN120526424AImage enhancementImage analysisMicroscopic imageSubcellular organelle
The invention relates to the technical field of image processing, and discloses a stem cell microscopic image feature extraction method and system. The method comprises the following steps: carrying out segmentation processing on a stem cell delay 3D confocal microscopic image through a chromatin texture sensitive adaptive threshold segmentation algorithm to obtain a nucleoplasm separation mask image; performing feature extraction processing on the marker fluorescence image according to the mask image to obtain a radial distribution feature vector and a pluripotency maintenance index; performing time sequence quantification processing on the state change sequence based on the index to obtain differentiation track feature data; performing spatial feature extraction processing on the subcellular organelle region through a topological graph construction algorithm to obtain a spatial correlation network graph; and performing feature fusion processing through a multi-layer perceptron fusion algorithm to obtain a stem cell image feature classification result. The accuracy of stem cell state recognition and the reliability of differentiation trajectory prediction are improved.
Owner:SHAANXI DEJIAN ZHONGPU BIOTECHNOLOGY CO LTD

Probiotic packaging stability control method based on deep learning

The invention discloses a probiotic packaging stability control method based on deep learning, and the method comprises the following steps: collecting multi-source data in a packaging process, and carrying out the preprocessing of the multi-source data; performing time sequence feature analysis on the standardized structured data set, and extracting multi-scale time sequence features; performing target segmentation and multi-dimensional structure feature extraction on the standardized microscopic image data set; feature fusion is carried out, a probiotic packaging stability feature space is constructed, and a stable feature vector is generated; inputting a time sequence prediction network, and carrying out time sequence modeling and prediction processing; performing control parameter adjustment and constraint optimization based on a difference value between a prediction result and stability reference data; and executing and updating the packaging control adjustment scheme according to feedback to complete a packaging control closed loop. According to the method, deep learning and multi-source data analysis are fused, intelligent prediction and adaptive control of the probiotic packaging process are realized, and the method has the advantages of high stability and high precision.
Owner:QINGDAO TIANTAI YINLEDUO FOOD CO LTD

Exosome automatic identification and analysis method based on microscopic imaging

The invention provides an exosome automatic identification and analysis method based on microscopic imaging, and belongs to the technical field of exosome identification and analysis, and the method comprises the steps: collecting an exosome fluorescence microscopic image, carrying out the preprocessing, and obtaining an exosome region through adaptive threshold segmentation and morphological processing. A GPU is adopted to process and extract morphological, texture and statistical feature matrixes in parallel, and meanwhile, the CPU recognizes an abnormal region. And combining the features to form a region feature set, inputting the region feature set into the preliminary screening model for scoring and screening high-credibility regions. Deep feature extraction is carried out on the high-credibility region, and multiple features are fused by using an attention fusion mechanism to construct vectors; and inputting a depth classifier to obtain a classification probability matrix and a screening result. And finally outputting the number, position, classification and credibility score of the exosomes. The problems that an existing exosome analysis method often depends on manual recognition, and automatic and high-throughput analysis is difficult to achieve are solved.
Owner:QINGDAO RAISECARE BIOTECHNOLOGY CO LTD