1632 results about "Femto second laser" patented technology

The invention is directed to a method and an arrangement for high-resolution microscopic imaging in laser endoscopy based on laser-induced object reaction radiation and for performing microscopic cuts in biological tissue. In using multiphoton processes for endoscopic applications in biological materials with an accuracy of under one millimeter, radiation of a pulsed femtosecond laser is focused into an object by means of a transmission focusing optics unit comprising a transmission system and miniature focusing optics having a high numerical aperture greater than 0.55 to trigger a local object reaction radiation in the micrometer to nanometer range, and the distal end of the transmission focusing optics unit is moved in at least two dimensions for highly spatially resolved scanning of the object and for transmitting object reaction radiation which is scanned in a locally progressive manner to an image-generating system with a photon detector. In an other embodiment the femtosecond laser radiation is energy enhanced is applied to the same transmission focusing optics unit to perform microendoscopic surgery in biological tissue.

Optical coherence tomography (OCT) is used to map the surface elevation and thickness of the cornea. The OCT maps are used to plan laser procedures for the treatment of an irregular, opacified or weakened cornea, and in the treatment of refractive errors. In the excimer laser phototherapeutic keratectomy (PTK) procedure, the OCT data is used to plan a map of ablation depth needed to restore a smooth optical surface. In the excimer laser photorefractive keratectomy procedure, OCT mapping of epithelial thickness is used to achieve clean laser epithelial removal. In femtosecond laser anterior keratoplasty procedure, OCT data is used to plan the depth of femtosecond laser dissection to remove an anterior layer of the cornea, leaving a smooth recipient bed of uniform thickness to receive a disk of donated corneal tissue. The linkage of an OCT system to a precise laser surgical system enables the performance of new procedures that are safer, less invasive and produce faster visual recovery than conventional surgical procedures.

Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be effected under gonioscopic control. Internal delivery may he controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

A laser system using ultrashort laser pulses is provided. In another aspect of the present invention, the system includes a laser, pulse shaper and detection device. A further aspect of the present invention employs a femtosecond laser and a spectrometer. Still another aspect of the present invention uses a laser beam pulse, a pulse shaper and a SHG crystal. In yet another aspect of the present invention, a multiphoton intrapulse interference phase scan system and method characterize the spectral phase of femtosecond laser pulses. Fiber optic communication systems, photodynamic therapy and pulse characterization tests use the laser system with additional aspects of the present invention.

Waveguides produced in bulk glass using femtosecond pulsed lasers have diameters and refractive index profiles that are manipulated by additional motions or beams. For example, spot focuses of the femtosecond pulsed lasers trace overlapping or widened tracks by superimposing additional relative motions between the spot focuses and the bulk glass. Additional femtosecond pulsed beams can also be used to produced widened waveguides.

A multifunctional optical micro-manipulation device comprises a femtosecond laser, an optical tweezers laser, an optical system, a stage, a light source system, an imaging system, a spectral measurement system and a computer, wherein the optical system comprises a shutter, an attenuator, a focusing lens, a near IR reflector and a microscopic objective lens; the light source system comprises an illumination light source and a condenser lens; the microscopic objective lens is arranged on the stage for condensing a laser beam emitted by a laser generator onto a sample; the condenser lens is arranged below the stage for condensing a visible light emitted by the illumination light source onto the sample; and the imaging system includes an IR filter and CCD camera sequentially disposed on the projection light path of the near IR reflector. By integrating three functions of laser tweezers, femtosecond laser scissors and microspectrometer in one system, the invention can overcome the singleness and the disadvantages of the prior laser micro-beam technology and can be widely used for studying in biological, medical, biophysical, material chemistry and nano-technology fields.

The present invention relates generally to methods for high throughput and controllable creation of high performance semiconductor substrates for use in devices such as high sensitivity photodetectors, imaging arrays, high efficiency solar cells and the like, to semiconductor substrates prepared according to the methods, and to an apparatus for performing the methods of the invention.

The invention discloses a terahertz pulse measurement-based burning temperature sensing device and a terahertz pulse measurement-based burning temperature sensing method. Laser is emitted from a femtosecond laser device, and is divided into reference laser and detection laser through a beam splitter, the detection laser is focused on a photoconduction antenna type terahertz emitter, terahertz pulses emitted by the terahertz emitter are focused on a ZnTe crystal through an off-axis paraboloid lens group; and the reference layer is collimated and is coincident with terahertz waves focused on the ZnTe crystal after passing through a semi-transmission and self-reflection mirror, parallel grating groups and a polarizing film, the terahertz waves are modulated by using Pockels effect of the ZnTe crystal, and image signals corresponding to collected first reference layer carrying terahertz pulse strength information and second reference laser not carrying the terahertz pulse strength information are input into a computer by a CCD (Charge Coupling Device) detector for subsequence processing. According to the invention, the precision and speed of the non-contact combustion measurement method are increased, and the non-contact measurement of combustion object temperature and temperature distribution is realized.

A method of providing a feature on a contact lens including applying a femtosecond laser beam to ablate at least a portion of the contact lens to provide the feature on the contact lens. In one embodiment, the femtosecond laser beam has a pulse width between 10×10⁻¹⁵ seconds and 200×10⁻¹⁵ seconds, and has a wavelength between 100 nm and 1500 nm. A contact lens is also provided including at least one fenestration fluidically connecting the anterior surface and the posterior surface, the fenestration being formed using a femtosecond laser in a manner that areas surrounding the fenestration are substantially free of heat damage.

A surgical procedure for implanting a lens or strengthening material in a cornea without making a flap as is done in Lasik procedures. A femtosecond laser or some future developed laser which has the same ability is modified to cut a pocket in the stroma layer of a cornea with no side cuts and only an opening at the surface of a cornea. Alternatively, a modified microkeratome shaped and sized to form the desired shape for a passageway bed cut which is cut to join a central bed cut. Alternatively, the passageway bed cut can be done using a femtosecond laser or some future developed laser which has the same ability. The passageway bed cut is smaller in dimension than a central bed cut of a pocket in which the lens will be implanted in procedures where an expandable lens or strengthening material is used. A modified microkeratome having a web, a central blade shaped to form the passageway bed cut and sled runner on either side of the blade and separated therefrom is also disclosed. A patient interface with a mask is also disclosed to allow a femtosecond laser or some future developed laser which has the same ability may also be used to form both the central bed cut and a passageway bed cut or only a single bed cut with an opening at the surface of the cornea to form the pocket is also disclosed.

The invention provides a preparation method of a super-hydrophobic micro-nano structure on a titanium alloy surface. The preparation method comprises the following steps: performing ultrasonic cleaning on a titanium alloy sample respectively with acetone and anhydrous alcohol, to obtain a titanium alloy sample with a clean surface; performing femtosecond laser photoetching processing on the surface of the titanium alloy sample with the clean surface, to obtain the titanium alloy sample with the surface having the super-hydrophobic micro-nano structure in one step, wherein a femtosecond laser beam is fixed and perpendicular to the surface of a processed material, the single pulse energy of the femtosecond laser beam is 100mu J-800mu J, the pulse width is 100fs-500fs, the central wavelength is 500nm-1000nm, the repetition frequency is 500Hz-2kHz, and the size of the etched facula of the femtosecond laser beam is 0.5mum-300mum; the surface of the titanium alloy sample moves relative to the etched facula of the femtosecond laser beam along the three-dimensional directions x, y and z, the motion positioning precision in x and y directions is 50nm-100nm, and the motion positioning precision in z direction is 5nm-10nm.

The invention relates to a method for selectively preparing or integrating multistage silver micro-nanostructures inside various plane substrates and micro fluidic chip channels by the utilization of the femtosecond laser inducing metallic silver reduction technology. In addition, the silver multistage micro-nanostructure substrate prepared by the method is used as a reinforced substrate for surface-enhanced raman spectroscopy SERS. The method provided by the invention comprises the following steps of: preparing a silver plating solution for femtosecond laser micro-nano machining, establishing a femtosecond laser micro-nano machining system for realizing multi-point scan in the silver plating solution, placing the silver plating solution and the substrate into the femtosecond laser micro-nano machining system and preparing the multistage silver micro-nanostructures on the substrate. According to the invention, a laser beam scans in the silver plating solution along a track designed in advance by a program. The preparation method is independent of the smoothness of the substrate. In particular, the preparation of silver multistage structure SERS substrate can be accomplished on the bottom of the micro fluidic chip channels, thus realizing catalysis and surface-enhanced raman test application.

A system and method are provided for reshaping the surface of a resilient transparent material such as a cornea. In the system, a laser unit generates a femto-second laser beam to deliver focused energy inside the material. Specifically, the energy is focused over a defined spot pattern to weaken the material. Further, the system includes a contact element that forms a contour surface. In order to reshape the material, the system provides for holding the contour surface of the contact element against the surface of the weakened material. After holding the contour surface against the material for a pre-determined time duration, the surface of the material is reshaped with a desired configuration that substantially mimics the contour surface of the contact element.

The invention relates to a laser shaping method of a multi-scale functional surface of micronano for semiconductor material, relating to micronano material preparation and laser micromachining technical field; the invention aims at providing a method and a device for preparing femtosecond laser of super-hydrophobic functionalization for microstructural surface based on the semiconductor material and through the systematically technical design of multi-scale surface micro-shaping and microstructural surface processing, and realizing optional and controllable preparation of semiconductor material surface having multi-scale microstructure such as micron, submicron and nano. The invention solves the technical problems such as high cost, low efficiency and difficult operation in traditional preparation methods of microstructural surface with super-hydrophobic function.

Disclosed are systems and methods for modifying a reticle. In general, inspection results from a plurality of wafers or prediction results from a lithographic model are used to individually decrease the dose or any other optical property at specific locations of the reticle. In one embodiment, any suitable optical property of the reticle is modified by an optical beam, such as a femto-second laser, at specific locations on the reticle so as to widen the process window for such optical property. Examples of optical properties include dose, phase, illumination angle, and birefringence. Techniques for adjusting optical properties at specific locations on a reticle using an optical beam may be practiced for other purposes besides widening the process window.

The invention discloses a structural light microscopic imaging system based on line scanning time-space focusing. The system comprises the components of a femto second laser device; an acousto-optical modulator which is used for periodically modulating light source strength according to a sine function; a line scanning module which is used for scanning in a linear focusing light spot direction and a vertical linear light spot function; a dispersion element which is used for generating a spatial chirp; a collimating lens which is used for focusing different frequency components after grating dispersion to a parallel transmission direction; a microscope module; and a synchronous control module which is used for performing synchronous controlling on the acousto-optical modulator, the line scanning module and the microscope module, thereby obtaining a reconstructed image. According to the structural light microscopic imaging system, the reconstructed image can be obtained through strength-modulated line scanning structural light illumination in a line scanning time-space focused scanning mode and strength change of synchronously modulated excited light, thereby improving resolution and contrast in line scanning time-space focusing and reducing excitation outside a focal plane caused by medium scattering.

A system and its method for creating a microchannel in the trabecular meshwork of an eye include a laser unit for generating a laser beam, and an imaging unit for creating an image of the trabecular meshwork. The system also includes a computer which defines the microchannel. A comparator that is connected with the computer then controls the laser unit to move the focal point of the laser beam. This focal point movement is accomplished to create the microchannel, while minimizing deviations of the focal point from the defined microchannel.

The invention relates to a method for preparing a micro optical element on a quartz glass substrate by applying femto-second laser, which is characterized by comprising three steps of femto-second laser irradiation, chemical etching and hydrogen-oxygen flame polishing. The method can achieve processing of any surface types including a plane, a standard spherical surface, a non-spherical surface and the like; and the step of the hydrogen-oxygen flame polishing only has a generated product of water, thus the method is environment-friendly, has quick polishing, avoids physical contacts and chemical reactions at the same time, and solves the difficulty which cannot be solved by a common polishing wheel because the high temperature of the flame can repair lattice damages caused by micro-machining.

The invention relates to a method for processing a micro array on glass surface via femtosecond laser pulse sequence belonging to the technical field of femtosecond laser application. The method comprises the following steps: (1) modulating the conventional femtosecond laser into the femtosecond laser pulse sequence including two sub-pulses on a time domain via a pulse shaping method, wherein the time interval range of two sub-pulses is 50fs-2ps, and the energy ratio range of two sub-pulses is 0.2-5; (2) focusing the femtosecond laser pulse sequence on the surface of glass material, scanning the required micro array configuration pattern on the glass surface according to the relative movement between the glass material and the laser focal point; (3) immersing the glass material with micro array configuration pattern obtained in the step (2) in a hydrofluoric acid solution with the concentration being 1-10%, carrying out reaction on the micro array configuration pattern region and the hydrofluoric acid solution so as to from a concave micro array structure. The modification degree of the femtosecond laser irradiation region is increased and the etching efficiency of the irradiation region is finally improved.

The invention relates to a fiber micro-nano Fabry-Perot interference type pressure sensor and a manufacturing method thereof, and belongs to the fiber sensor technical field; the pressure sensor is formed by fusing a fiber (1) with a fiber film (2), wherein an end face of the fiber is provided with a micropore, and an end face of the fiber film (2) is complete; a fuse surface and the micropore form an embedded Fabry-Perot micro-cavity; the manufacturing method comprises the following steps: using a femto second laser to process the micropore on the end face fo the fiber; fusing the fiber with the other fiber having the complete end face so as to form the Fabry-Perot micro-cavity; cutting and grinding the fiber length on one end to several micrometers so as to form a fiber thin film, and forming the pressure sensor with a micro-nano structure. Compared with the prior art, a sensor head is in micro-nano size, so temperature has small intersect influence for pressure measurement; the sensor is made of quartz material with same performance, so thermal expansion coefficient is consistent, and structure is stable; considering material and a making process, the pressure sensor is high temperature resistant, has micro structure, is anti-electromagnetic interference, anti pollution, high in reliability, and high in precision.

The invention relates to a normal-temperature normal-pressure femto-second CARS (Coherent Anti-stokes Raman Spectroscopy) time-resolved spectrum measuring system which relates to the technical field of nonlinear optics and solves the problem of multiple limiting factors of traditional femto-second CARS time-resolved spectrum measuring experiment. Beams output by a femto-second laser are adjusted through a series of reflectors and optical delay lines by the system to form three bundles of beams which have approximate energy and are respectively positioned on three peaks of a square on the vertical direction of the beams, the beams are focused to a sample pool and then emit a new beam along a specific angle, i.e. a CARS signal, the CARS signal is filtered through a filter plate, then received by a probe and input to a monochromator, the data acquisition of an electrical signal converted by a photomultiplier is carried out by utilizing BOCCAR, and the data are input to a computer for data processing. The invention can carry out femto-second CARS time-resolved spectrum measurement under the experimental conditions of normal temperature and normal pressure and is applicable for the femto-second CARS spectrum measurement of gas samples and liquid samples in a static sample pool.

Systems and methods are provided for disrupting tissue within preretinal or retinal structures of an eye. At least one femtosecond laser pulse is directed through the cornea of the eye to a target location. The at least one femtosecond laser pulse has sufficient intensity to induce nonlinear absorption in tissue within the target location. The at least one laser pulse is corrected at an adaptive optical element as to substantially reduce dispersion and aberration of the at least one laser pulse due to changes in the wavefront profile associated with the laser pulse due to travel through eye tissue between the surface of the eye and the target location. At least the target location is imaged to produce an in vivo image of the target location. The adaptive optical element is adjusted according to distortion detected in a reflected wavefront.

The invention relates to a system and a method for detecting and identifying Chinese herbal medicine. In the invention, terahertz which is radiated from gallium arsenide under the excitation of femto-second laser is used for researching Chinese herbal medicine so as to achieve the purpose of distinguishing true and false Chinese herbal medicine and detecting the quality of the Chinese herbal medicine. In the system and the method, the femto-second laser is divided into pump light and detection light by a beam splitter; after being modulated by a chopper and an attenuator, the pump light is focused by a focusing lens onto the gallium arsenide to give off the terahertz; the radiated terahertz is focused onto a tested Chinese herbal medicine sample by two parabolic mirrors; a terahertz signal with Chinese herbal medicine information is collected and focused onto an electro-optic crystal by another two parabolic mirrors; and detection light is also focused onto the electro-optic crystal by a delay device so as to detect the terahertz signal with the Chinese herbal medicine information. The corresponding terahertz absorption spectrum is calculated after Fourier transform, and then the Chinese herbal medicine can be quickly and effectively identified and screened by a support vector machine method.