133 results about "Intraocular pressure" patented technology

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allows for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and that may restore or maintain at least partial patency of the canal without substantially interfering with transmural or transluminal fluid flow across the canal. The devices utilize the natural drainage process of the eye and may be implanted with minimal trauma to the eye. Kits may include a support and an introducer for implanting the support within Schlemm's canal. Methods may include implanting a support within Schlemm's canal, where the support is capable of restoring or maintaining at least partial patency of the canal without substantial interference with transmural or transluminal fluid flow across the canal.

The invention relates to the technical field of intelligent medical treatment, and discloses a cataract surgery navigation control method based on multi-modal fusion, which comprises the following steps: carrying out lightweight preprocessing on an eye fundus image, ultrasonic probe data, a corneal topographic map and intraocular pressure parameters through an edge computing architecture, and constructing an efficient feature extraction network by adopting a knowledge distillation technology; self-adaptive feature fusion is realized based on an uncertainty quantification mechanism, real-time structure recognition is provided by utilizing an augmented reality technology, an intelligent navigation strategy is generated by pre-training a reinforcement learning model, an instrument control system with multilayer safety guarantee is established, and continuous optimization of the system is realized by adopting an online learning mechanism. According to the invention, the precision and safety of the operation are effectively improved, and an effective technical scheme is provided for intelligent navigation control of the cataract operation.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

The invention discloses a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, and relates to the technical field of medical instrument testing, the device comprises an eyeball environment simulation part and a suture cornea loading part, the suture cornea loading part comprises a scraping assembly and a transmission assembly, the eyeball environment simulation part comprises an intraocular pressure bubbling instrument, a hydraulic pipe, a T-shaped pipe and a tear pipe, the tear pipe is communicated with the scraping assembly, an opening in the lower end of one side of the T-shaped pipe is connected with the intraocular pressure bubbling instrument through the hydraulic pipe, and an opening in the lower end of the other side of the T-shaped pipe is provided with a hydraulic sensor. According to the device and method for simulating eyelid scraping, intraocular pressure loading and suture tension monitoring, the uniformity of cornea suture is achieved, secondary cornea damage caused by uneven suture is reduced, the risk of postoperative complications is reduced, and an experimental basis is provided for research and development of cornea substitutes.

Systems and methods for preparation of an implant and ab interno insertion of the implant into an eye of a patient including a tissue cartridge configured to receive and hold a patch of a material; a cutting device; and a delivery device. Related devices, systems, and methods are provided.

The invention discloses a dioptric scleroderma cataract dynamic intraocular pressure stable control ultrasonic emulsification system adaptive to a dual-channel operation, which comprises a host control unit, an ultrasonic emulsification handle, a perfusion and suction system, an intraocular pressure monitoring unit, a pressure balance module and a scleroderma fragmentation module, through cooperation of the intraocular pressure control module and the two-way operation type adaptive control module, a high-precision filling valve and a closed-loop suction pump are synchronously adjusted in real time according to anterior chamber built-in and external monitoring fusion data, and intraoperative intraocular pressure fluctuation is controlled within + / -2 mmHg; through pulse modulation and a self-adaptive negative pressure curve of the hardcore fragmentation enhancement module, the stability of the anterior chamber is ensured while the hardcore fragmentation efficiency is improved; fluid dynamics and energy parameters can be automatically optimized according to conventional incisions or micro incisions; according to the system, the anterior chamber stability problem in the high-difficulty cataract surgery is solved.

The invention discloses an eye vision light health management system, and relates to the technical field of vision health management systems, the system specifically comprises data management and service management, the data management comprises a data acquisition module, a data processing module, a data identification module and a data transmission module, and the service management comprises tour service, store arrival service and remote service. According to the eye vision light health management system, through cooperation of the data acquisition module, the data processing module, the data identification module and the data transmission module, a detection mode of integrating intelligent wearable equipment and an eye vision light detection instrument to detect key indexes of vision data, intraocular pressure and diopter of a patient is adopted, a single detection mode is replaced, and meanwhile, the detection efficiency is improved. The integration of the intelligent wearable device and the eyesight light detection instrument also saves the step of manual recording of the detection data by the staff, thereby improving the accuracy of the eyesight detection data of the patient.

The invention relates to the field of medical health, and aims to provide an intraocular pressure measuring device and a measuring method so as to reduce the operation difficulty of a user and improve the measuring accuracy. According to the technical scheme, the intraocular pressure measuring device is characterized by comprising a telescope barrel with an eyeshade, a springback type pressure measuring module arranged in the telescope barrel, a position adjusting module connected with the telescope barrel and the springback type pressure measuring module, and a controller electrically connected with the position adjusting module and the springback type pressure measuring module.

The present invention relates to the use of selective aquaporin inhibitors, e.g., of aquaporin-4 or aquaporin-2, e.g., certain phenylbenzamide compounds, for the prophylaxis, treatment and control of aquaporin-mediated conditions, e.g., diseases of water imbalance, for example edema (particularly edema of the brain and spinal cord, e.g., following trauma or ischemic stroke, as well as the edema associated with glioma, meningitis, acute mountain sickness, epileptic seizures, infections, metabolic disorders, hypoxia, water intoxication, hepatic failure, hepatic encephalopathy, diabetic ketoacidosis, abscess, eclampsia, Creutzfeldt-Jakob disease, and lupus cerebritis, as well as edema consequent to microgravity and / or radiation exposure, as well as edema consequent to invasive central nervous system procedures, e.g., neurosurgery, endovascular clot removal, spinal tap, aneurysm repair, or deep brain stimulation, as well as retinal edema), as well as hyponatremia and excess fluid retention, and diseases such as epilepsy, retinal ischemia and other diseases of the eye associated with abnormalities in intraocular pressure and / or tissue hydration, myocardial ischemia, myocardial ischemia / reperfusion injury, myocardial infarction, myocardial hypoxia, congestive heart failure, sepsis, and neuromyelitis optica, as well as migraines, as well as to novel assays for identifying aquaporin inhibitors.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

The invention relates to the technical field of intraocular pressure measurement, and discloses an artificial eyeball and an intraocular pressure monitoring simulation platform and method. The method comprises the following steps: controlling a water pressure regulator to regulate water pressure in a water injection pipeline and an artificial eyeball according to an intraocular pressure data model; a pressure sensor in the artificial eyeball senses and obtains a pressure electric signal in the artificial eyeball in real time; the pressure electric signal is transmitted to a transmitting coil through a signal wire, and the transmitting coil transmits the pressure electric signal to a receiving coil outside the artificial eyeball through mutual inductance; the receiving coil and the transmitting coil are in mutual inductance communication to receive and obtain a pressure electric signal, and the signal acquisition device acquires the pressure electric signal of the receiving coil to obtain an intraocular pressure measurement value; the actual intraocular pressure value is obtained by conducting signal collection on the water pressure sensor. By applying the system, the function of simulating the adjustable aqueous humor pressure and the blinking action can be achieved, high integration and intelligence are achieved, and accurate control and real-time monitoring of the change of the internal pressure of the simulated eyeball can be achieved.

The invention discloses an intelligent bed control method, device and equipment and a storage medium. According to the intelligent bed control method, the intelligent bed is controlled to adjust the posture of the bed body based on the target eye yoga content selected by the service object so as to assist the service object in executing the target eye yoga content; obtaining intraocular pressure monitoring data collected by intraocular pressure monitoring equipment in real time; and after the target eye yoga content is completed, controlling the intelligent bed to adjust the posture of the bed body according to the intraocular pressure monitoring data. According to the intelligent bed control method, the intelligent bed is controlled to adjust the posture of the bed body based on the target eye yoga content, a bed body auxiliary function for eye relaxation is provided for the service object, and the service object can be helped to better complete the body type so as to effectively relieve eye fatigue; after the target eye yoga content is completed, the intelligent bed is controlled to adjust the posture of the bed body according to the intraocular pressure monitoring data, the service object is further helped to be adjusted to the comfortable prone posture suitable for the eye health condition, and therefore the more continuous and more effective eye relaxing effect is achieved.

The invention relates to the technical field of medical instruments, in particular to an intraocular pressure sensor which comprises an intraocular pressure sensor body and a support connected with the intraocular pressure sensor body. The support is of a plate-shaped structure. According to the intraocular pressure sensor, the requirement for the stability of the position of the intraocular pressure sensor is high in the intraocular pressure detection process based on optical sensing, the support of a plate-shaped structure is adopted, the comfort degree after implantation is guaranteed, meanwhile, the intraocular pressure sensor body is prevented from moving, the stability of the position of the intraocular pressure sensor body is improved, and the intraocular pressure sensor is suitable for popularization and application. Therefore, frequent adjustment of the shooting angle in the detection process can be avoided, the shooting difficulty is reduced, and the definition of the shot image is improved.

A biosensor includes a periodic crystalline structure first layer, and an amorphous crystalline structure second layer. The first and second layers are formed from a biocompatible silicone having a Young's Modulus E between 0.4 and 2.0 MPa. The biosensor has a pressure dependent NIR resonance peak shift of less than 15 nm over a field of view of 40°, and has an optical pressure sensitivity of between 0.38 and 2.6 nm / mm Hg. The biosensor may be formed by forming a 3D crystalline structure having a periodic amorphous crystalline first layer and an amorphous crystalline second layer. Voids of the 3D crystalline structure are filled with the biocompatible silicone / polydimethylsiloxane a material. The 3D crystalline structure is removed to form an inverse structure having a first volume of an amorphous arrangement of voids and a second volume of a periodic arrangement of voids.

The present disclosure discloses a fluid collection box for phacoemulsification surgery, including a case composed of a front plate, a body, and a rear plate. The case communicates with a waste liquid bag. The body has a perfusion passage and a suction passage that are disposed independently. The perfusion passage is a sealed circulation cavity defined by a cover and the body. The circulation cavity communicates with a first connection port and a second connection port on the body for perfusion. There is a gap between the cover and the body. Connection and disconnection of the perfusion passage is controlled by pressing the cover. The suction passage is a pipeline that communicates a third connection port with the waste liquid bag, and performs perfusion by a peristaltic pump. The suction passage further communicates with a negative pressure regulating loop, to regulate pressure within the suction passage. According to the present disclosure, the perfusion passage and the suction passage are independently disposed, so that the two do not interfere with each other and work independently. Meanwhile, it is ensured that pressure within the perfusion passage is stable, thereby reducing changes of intraocular pressure, and improving safety during use.

An insertion device for an ocular implant for regulating intraocular pressure includes a cannula having an internal space for receiving at least a portion of an ocular implant having a stent and an implant opening for inserting the ocular implant; a handle configured to be connected to the cannula and held by a surgeon; and a holder configured to be coupled to the handle and including a receiving portion configured to receive the stent of the ocular implant. The ocular implant insertion device appropriately fixes the stent inserted into the tube of the ocular implant in a manner attached to the insertion device, thereby preventing problems such as the stent coming out of the tube, the implant being separated from the insertion device by the stent, or the stent obscuring the surgeon's field of vision during implant implantation surgery.

The present invention discloses an intraocular pressure detection device and method. The intraocular pressure detection device includes: a detection shell, a processing module, a first detection module, a second detection module and a pressurizing module; the detection shell includes a handheld portion and a detection portion; the pressurizing module, the first detection module and the second detection module are located at one end of the detection portion away from the handheld portion; the processing module is connected to the first detection module and the second detection module respectively; the processing module is connected to the pressurizing module, and the pressurizing module is used to be placed on the first eye when detecting the intraocular pressure of the subject; the processing module is used to control the pressurizing module to apply pressure to the first eye when the current pressure values detected by the first detection module and the second detection module both reach a reference pressure value, and obtain the target eyeball pressure value detected by the second detection module when the pressure applied by the pressurizing module reaches a preset value. The technical solution of the embodiment of the present invention improves the convenience of the intraocular pressure detection device and improves the accuracy of intraocular pressure detection.

The invention discloses an optical system for high-speed reduction of a dynamic deformation process of a cornea, which realizes high-precision analysis of physical characteristics of the cornea through a high-speed imaging technology, performs error compensation on the physical characteristics and realizes high-precision calculation of intraocular pressure. According to the technical scheme, the optical system comprises a slit lamp light source used for forming a cornea optical slice and ensuring the definition and the contrast ratio of a cornea slice image; the Samm lens is used for shooting a cornea optical section, inclined imaging light path design is adopted, and the depth of field meets the requirement that the cornea section keeps clear imaging in the dynamic process; and the high-speed camera is positioned behind the Chemma lens and is used for receiving the cornea optical slice image imaged by the Chemma lens so as to record the dynamic deformation process of the cornea.

The invention discloses a vibratory massage intelligent control eye care device, and belongs to the technical field of medical care equipment. The problems that an existing eye massager is single in function and cannot meet various scene requirements are solved, real-time monitored intraocular pressure, temperature and myoelectricity activity data are compared with threshold values to calculate error values, massage parameters are dynamically adjusted through a PID algorithm, it is ensured that the vibration frequency and intensity are always within a safe and effective range, and the effect of improving the quality of the eye massager is achieved. Therefore, the individuation and adaptability of the eye massage instrument are improved, and a patient is ensured to obtain comfortable and effective massage experience. By analyzing and calculating intraocular pressure, temperature and myoelectricity activity data and vibration frequency and intensity parameters of a patient, it is ensured that each treatment is adjusted based on the previous treatment effect, and therefore fine management and personalized adjustment of the eye nursing process of the patient are achieved; and the satisfaction degree of the patient and the pertinence and effectiveness of massage treatment are improved.

The present disclosure generally relates to devices for pressure sensing and drug delivery applications. In some aspects, devices comprising a reservoir in fluidic communication with a channel defined between two deformable polymer lenses are provided. In some embodiments, the reservoir contains a scaffold configured to reversibly absorb or release a fluid into the channel in response to a volume change of the reservoir, for example, due to an applied external pressure. In some cases, the distance traveled by the fluid is proportional to the change in volume of the reservoir. Other aspects of the disclosure relate to methods of using such devices. For example, in some embodiments, the methods relate to determining an intraocular pressure within an eye of a subject, for example, suspected of having an eye disease or disorder.

The invention discloses a modular integrated rapid ophthalmology screening vehicle and an examination method thereof, and relates to the technical field of ophthalmology examination. The inspection mechanism is mounted on the rear side of the bottom inner wall of the screening vehicle body; the two shading mechanisms are mounted between the top inner wall and the bottom inner wall of the screening vehicle body; through cooperative work of the vision detection module, the fundus imaging module, the intraocular pressure detection module, the slit lamp module and the AI auxiliary diagnosis module, and efficient interconnection between equipment in each module and the host server through USB-C and HDMI dual interfaces with unified specifications, the functional modules can be flexibly increased or decreased according to requirements of different screening scenes; the problems that a traditional whole machine integrated device is complex in structure and large in deployment difficulty are solved, multi-dimensional detection such as refraction detection, fundus imaging and intraocular pressure measurement can be completed through professional devices of all the modules, the screening efficiency and diagnosis accuracy are greatly improved, and the coverage range of ophthalmology screening service is effectively expanded.

The invention discloses a multi-mode simulation device and method for intraocular pressure. The simulation device comprises a track vertically arranged on the base table, a clamp is connected to the track in a sliding mode, a first liquid storage pipe with an opening in the top is installed on the clamp, the first liquid storage pipe is connected with a second liquid storage pipe through a flexible connecting pipe, and the first liquid storage pipe, the second liquid storage pipe and the flexible connecting pipe are filled with testing liquid; a temperature control module comprising a temperature sensor and a heater is arranged on the outer wall of the second liquid storage pipe; a simulated intraocular pressure measuring end is arranged at the top of the second liquid storage tube; and a distance measurement display module is arranged right above the first liquid storage pipe. The problems of mechanical pressure drifting and slow dynamic response are solved while intraocular pressure simulation precision and dynamics are guaranteed, multi-mode pressure control is achieved, practicability is high, a reliable platform is provided for medical instrument testing and pathological research, and animal experiments can be effectively replaced.