37 results about "Intraocular pressure" patented technology

The invention discloses a dioptric scleroderma cataract dynamic intraocular pressure stable control ultrasonic emulsification system adaptive to a dual-channel operation, which comprises a host control unit, an ultrasonic emulsification handle, a perfusion and suction system, an intraocular pressure monitoring unit, a pressure balance module and a scleroderma fragmentation module, through cooperation of the intraocular pressure control module and the two-way operation type adaptive control module, a high-precision filling valve and a closed-loop suction pump are synchronously adjusted in real time according to anterior chamber built-in and external monitoring fusion data, and intraoperative intraocular pressure fluctuation is controlled within + / -2 mmHg; through pulse modulation and a self-adaptive negative pressure curve of the hardcore fragmentation enhancement module, the stability of the anterior chamber is ensured while the hardcore fragmentation efficiency is improved; fluid dynamics and energy parameters can be automatically optimized according to conventional incisions or micro incisions; according to the system, the anterior chamber stability problem in the high-difficulty cataract surgery is solved.

Disclosed herein are drug delivery devices and methods for the treatment of ocular disorders requiring targeted and controlled administration of a drug to an interior portion of the eye for reduction or prevention of symptoms of the disorder. The devices are capable of controlled release of one or more drugs and may also include structures which allow for treatment of increased intraocular pressure by permitting aqueous humor to flow out of the anterior chamber of the eye through the device.

The present disclosure discloses a fluid collection box for phacoemulsification surgery, including a case composed of a front plate, a body, and a rear plate. The case communicates with a waste liquid bag. The body has a perfusion passage and a suction passage that are disposed independently. The perfusion passage is a sealed circulation cavity defined by a cover and the body. The circulation cavity communicates with a first connection port and a second connection port on the body for perfusion. There is a gap between the cover and the body. Connection and disconnection of the perfusion passage is controlled by pressing the cover. The suction passage is a pipeline that communicates a third connection port with the waste liquid bag, and performs perfusion by a peristaltic pump. The suction passage further communicates with a negative pressure regulating loop, to regulate pressure within the suction passage. According to the present disclosure, the perfusion passage and the suction passage are independently disposed, so that the two do not interfere with each other and work independently. Meanwhile, it is ensured that pressure within the perfusion passage is stable, thereby reducing changes of intraocular pressure, and improving safety during use.

An insertion device for an ocular implant for regulating intraocular pressure includes a cannula having an internal space for receiving at least a portion of an ocular implant having a stent and an implant opening for inserting the ocular implant; a handle configured to be connected to the cannula and held by a surgeon; and a holder configured to be coupled to the handle and including a receiving portion configured to receive the stent of the ocular implant. The ocular implant insertion device appropriately fixes the stent inserted into the tube of the ocular implant in a manner attached to the insertion device, thereby preventing problems such as the stent coming out of the tube, the implant being separated from the insertion device by the stent, or the stent obscuring the surgeon's field of vision during implant implantation surgery.

The invention discloses a modular integrated rapid ophthalmology screening vehicle and an examination method thereof, and relates to the technical field of ophthalmology examination. The inspection mechanism is mounted on the rear side of the bottom inner wall of the screening vehicle body; the two shading mechanisms are mounted between the top inner wall and the bottom inner wall of the screening vehicle body; through cooperative work of the vision detection module, the fundus imaging module, the intraocular pressure detection module, the slit lamp module and the AI auxiliary diagnosis module, and efficient interconnection between equipment in each module and the host server through USB-C and HDMI dual interfaces with unified specifications, the functional modules can be flexibly increased or decreased according to requirements of different screening scenes; the problems that a traditional whole machine integrated device is complex in structure and large in deployment difficulty are solved, multi-dimensional detection such as refraction detection, fundus imaging and intraocular pressure measurement can be completed through professional devices of all the modules, the screening efficiency and diagnosis accuracy are greatly improved, and the coverage range of ophthalmology screening service is effectively expanded.

The invention discloses a multi-mode simulation device and method for intraocular pressure. The simulation device comprises a track vertically arranged on the base table, a clamp is connected to the track in a sliding mode, a first liquid storage pipe with an opening in the top is installed on the clamp, the first liquid storage pipe is connected with a second liquid storage pipe through a flexible connecting pipe, and the first liquid storage pipe, the second liquid storage pipe and the flexible connecting pipe are filled with testing liquid; a temperature control module comprising a temperature sensor and a heater is arranged on the outer wall of the second liquid storage pipe; a simulated intraocular pressure measuring end is arranged at the top of the second liquid storage tube; and a distance measurement display module is arranged right above the first liquid storage pipe. The problems of mechanical pressure drifting and slow dynamic response are solved while intraocular pressure simulation precision and dynamics are guaranteed, multi-mode pressure control is achieved, practicability is high, a reliable platform is provided for medical instrument testing and pathological research, and animal experiments can be effectively replaced.

The invention relates to the technical field of vision change prediction, in particular to a vision change prediction method based on a random forest algorithm. The method comprises the following steps: S1, collecting basic data related to vision change; s2, identifying features having significant influence on vision change by using a vision correlation method; s3, using a random forest as a prediction model, and training the prediction model through a retraining mechanism; and S4, performing vision change prediction on the new data by using the trained prediction model. According to the technology, through detailed data preprocessing steps including missing value removal or filling, abnormal value processing, data standardization or normalization and feature selection, the data quality and effectiveness of an input model are ensured, in addition, the vision correlation coefficient is optimized, and the accuracy of the vision correlation coefficient is improved. Particularly, the nonlinear relation and interaction among age, intraocular pressure and diopter are considered, so that the model can more accurately capture key influence factors of vision change.

The present application relates to vitrectomy technical field, specifically disclose a kind of accurate oil exchange method and its control system in minimally invasive vitrectomy, to the problems of mutual interference, intraocular pressure fluctuation, artificial push and team cooperation caused by the same channel shared by silicon oil injection and perfluorocarbon liquid suction in prior art, the present application is physically connected by three-way component silicon oil catheter and the silicon oil perfusion control interface of vitrectomy equipment, using gas-liquid exchange air pump to provide continuous stable air pressure power source, to drive silicon oil injection with constant working pressure;At the same time, by the single manual control of surgeon suction path, according to visual observation real-time adjustment suction speed, realize the independent double-channel control and dynamic balance of silicon oil injection and perfluorocarbon liquid suction.The present application is based on the high viscosity of silicon oil and the stable voltage characteristics of air pressure power source, significantly improves the accuracy, stability and safety of operation, reduces the operation difficulty and team cooperation dependence.

The application discloses a flexible ultrasonic patch for monitoring corneal elastic modulus and a preparation method thereof, the patch comprises, from top to bottom, a top flexible packaging layer, a top electrode layer, a piezoelectric layer, a bottom electrode layer, a bottom flexible base material isolation layer and a bottom flexible packaging layer; the piezoelectric layer is internally provided with an air column. Compared with a traditional medical hard probe for measuring corneal mechanical properties, the application has good flexibility, and the tensile property and bending resistance are greatly improved; the patch can be dynamically attached to the surface of an eyelid, and long-time corneal health monitoring of a human body can be realized; meanwhile, a non-invasive monitoring mode widens the application scene of the device, and real-time monitoring of corneal elastic modulus during a sleep process at night can be realized, and other eye features such as intraocular pressure can be further obtained.

The invention provides a scleroscope device for noninvasive monitoring of an aqueous humor outflow coefficient, a monitoring method and a system, relates to the technical field of medical monitoring equipment for the ophthalmology department, and solves the problems that an aqueous humor outflow coefficient measuring method in the prior art is high in invasiveness, incapable of achieving continuous monitoring, insufficient in precision and poor in data synchronism. The sclera lens device comprises a sclera lens, the sclera lens comprises a central area, an edge landing area and a transition area connecting the central area and the edge landing area, and the edge landing area is used for making contact with the sclera of a user and providing support for the transition area and the central area; the phased array transducer matrix comprises a plurality of transducers which are annularly distributed in the transition area; the dynamic deflection control module is arranged in the transition area and is electrically connected with each transducer so as to control the excitation time delay of each transducer; the intraocular pressure monitoring module is arranged in the central area; and the signal processing module is arranged in the transition area.

A shunt operable to be implanted on an eye is provided. The shunt includes a vein fluidic channel operable to be in fluid communication with an interior of the eye and operable to receive aqueous fluid from the interior of the eye. A body is fluidly coupled with the vein fluidic channel. A valve is disposed within the body and is operable to regulate intraocular pressure in the eye by opening and closing based on pressure from the aqueous fluid. A plurality of outlets are in fluid communication with the body opposite the vein fluidic channel in relation to the valve. The outlets are operable to release the aqueous fluid to the sclera of the eye.

The invention discloses an intraocular pressure measurement method based on a non-contact technology, and relates to the technical field of intraocular pressure detection.The intraocular pressure measurement method comprises the steps that speckle images are collected and enhanced, structured light is fused to obtain a three-dimensional point cloud, and a cornea initial geometric matrix is obtained through fitting; controlling an airflow nozzle to be automatically aligned according to the normal direction of the cornea based on the initial geometric matrix, carrying out frequency sweeping resonance excitation, collecting optical, speckle and acoustic three-channel responses, then carrying out time registration and feature consistency alignment, extracting cornea resonance feature vectors through short-time Fourier transform, and obtaining estimated intraocular pressure in combination with mechanical spectrum inversion. Stable intraocular pressure is obtained through nonlinear self-correction and residual feedback, and finally measurement data are calculated and output in combination with optical, acoustic and frequency spectrum modal consistency verification and confidence interval calculation. The controllable triggering of the cornea multi-order mechanical response under the low-energy excitation is realized through the automatic alignment of the airflow nozzle according to the normal direction of the cornea and the adoption of the sweep-frequency resonance excitation.

A virtual reality (VR) system can be implemented for vision testing and eye health monitoring. The system utilizes an electronic device equipped with a high-resolution VR headset, eye-tracking sensors, and wearable devices capable of measuring intraocular pressure, tear film stability, and ocular blood flow. The device generates a VR user interface corresponding to a three-dimensional virtual environment and renders it on the VR headset. Within this environment, the system conducts a series of vision tests. Throughout these tests, the system continuously monitors eye movements using the eye-tracking sensors and collects vital data from the wearable devices. This data is then evaluated to assess both visual performance and overall eye health, providing a more holistic view of the user's ocular condition in a controlled virtual setting.

This invention provides a wearable contact lens, an active continuous intraocular pressure (IOP) monitoring method, and a device. The wearable contact lens includes: a structural layer, the working surface of which conforms to the wearer's cornea and eyelids, and compresses or releases the cornea with eyelid movement; a sensing layer, located on the side of the structural layer closest to the cornea, containing multiple pressure sensor arrays, which acquire current pressure data and current pressure area of ​​the cornea when the wearer's eyelids descend to a preset position; and a control system, which calculates and outputs the current IOP based on the current pressure data and current pressure area acquired by the sensing layer. This invention obtains the user's IOP by acquiring the force and flattened area of ​​the cornea, without requiring any external force, achieving active and continuous IOP monitoring. It is convenient, quick, and provides high accuracy.

The invention provides an intelligent intraocular pressure dynamic glasses monitoring method and system based on multi-modal sensing, and relates to the technical field of glasses monitoring, and the method comprises the steps: carrying out the determination of a monitoring point position and the collection of point position multi-modal data through an eye sensor and a pose sensor which are disposed in glasses, and obtaining the point position multi-modal collection data; performing multi-modal and intraocular pressure data influence analysis on the point location multi-modal acquisition data to obtain multi-modal influence analysis data and intraocular pressure influence analysis data; according to the multi-modal influence analysis data, combined with the intraocular pressure influence analysis data, multi-modal intraocular pressure dynamic analysis is carried out, multi-modal intraocular pressure dynamic monitoring data is obtained, and through multi-dimensional data collection and fusion analysis, the scene flexibility and the precision accuracy are greatly improved.

To provide a patient treatment system for determining an eye health index value representing the health or disease state of a patient's eye.SOLUTION: Various eye conditions can be treated, such as by monitoring a patient's eye health and using information about the patient's intraocular pressure (IOP) characteristics, information about the patient's blood pressure (BP) characteristics, and information about patient treatment, such as from a patient treatment system. In an example, a quantitative eye health index can be determined for a patient based on IOP characteristics, BP characteristics, and information about patient treatment.SELECTED DRAWING: Figure 1

The application provides a multifunctional health monitoring contact lens and a preparation and detection method thereof, comprising a contact lens body, wherein the contact lens body comprises a multifunctional detection module, and the multifunctional detection module comprises: a Raman enhancement substrate, which is fixedly arranged at an iris area on the outer surface of the contact lens body; a specific polypeptide with a Raman label is modified on the Raman enhancement substrate, which is used for changing the Raman scattering intensity of the specific polypeptide on the surface, so as to realize quantitative detection of biological macromolecules in a to-be-detected solution; a three-electrode substrate, which is fixedly arranged at the iris area on the outer edge of the contact lens body, and is used for quantitatively detecting biological small molecules in the to-be-detected solution based on an electrochemical method; and a photonic crystal substrate, which is fixedly arranged at the iris area of the contact lens body, and is used for realizing visual detection of intraocular pressure based on the spectral change of the photonic crystal substrate. The application can realize qualitative and quantitative detection of related substances, is convenient and accurate, and improves the functional diversity and expandability of the contact lens.

The invention relates to the technical field of medical health, in particular to a senile eye disease patient safety medication nursing data checking and reminding system which obtains intraocular pressure, blood sugar, heart rate and medication records of a patient in real time through a data acquisition module; a reinforcement learning model module is used for analyzing data, and an individualized drug effect-physiological index correlation model is constructed; personalized medication suggestions are generated through a dose self-adaptive adjustment module and prompts are pushed; a drug sensitivity attenuation modeling module is innovatively adopted to predict long-term drug effect change, and a clinical rule constraint module is combined to ensure medication safety; and finally, local real-time decision and cloud collaborative updating are realized through an edge computing deployment module. According to the invention, individualization, dynamics and safety of medication management are realized, and the quality and safety of medication nursing of old eye disease patients are effectively improved.

The invention relates to the technical field of intraocular pressure treatment, and discloses an intraocular pressure reduction training device which comprises a support unit, a virtual display unit, an audio stimulation unit, a transcranial stimulation unit and a control unit. The bracket unit comprises a top side part, a rear side part and two lug parts; the virtual reality unit comprises display glasses; the audio stimulation unit comprises two loudspeakers, the two loudspeakers are used for playing beat frequency music, and the beat frequency music has an audio frequency difference; the transcranial stimulation unit comprises two first stimulation media, and the first stimulation media are used for carrying out transcranial electrical stimulation or transcranial magnetic stimulation; according to the intraocular pressure reduction training device provided by the invention, various intraocular pressure reduction trainings can be performed on a user in a single treatment course through the display glasses, the loudspeaker and the first stimulation medium, so that the effect of increasing and reducing the intraocular pressure of the user is achieved.

The present disclosure relates to a method of manufacturing a keratoprosthesis exhibiting excellent physical properties by stabilizing the interface of an adhesive optical unit and a support unit through a keratoprosthesis mold and UV dose adjustment. The present disclosure can stably adhere an interface between the optical unit and the support unit by manufacturing the optical unit for 1-4 hours using low dose UV in the keratoprosthesis mold, thereby manufacturing the keratoprosthesis in which the optical unit and the support unit are integrated. The artificial cornea manufactured by the manufacturing method has a constant spherical shape and is convenient for center positioning, so that the success rate of an operation can be improved during the operation; the central part of the optical unit shows uniform and excellent physical properties, so that the physical safety in a human body can be further improved; moreover, the interface of the optical unit and the support unit shows excellent physical properties which are equivalent to about 100 times of the existing intraocular pressure, so that the separation of the optical unit and the support unit caused by intraocular pressure in the human body can be prevented at an early stage. Furthermore, by means of the manufacturing method, the eye appearance of a patient to which the artificial cornea is transplanted can be improved, and complications and side effects caused by adhesive substances can be reduced.

The invention relates to the technical field of intraocular pressure measurement, and aims to solve the problems that existing intraocular pressure measurement equipment generates measurement errors due to uneven local stress, single data based on a single sensor causes poor repeatability of measurement data, and the data stability and the like have obvious defects. According to the non-corneal contact intraocular pressure measuring device and method based on the array type pressure sensors, a core measuring area and an auxiliary calibration area collect pressure data through a plurality of pressure sensors, and through the structure of the multi-point thin film array type distributed pressure sensors, a multi-measuring-point signal fusion algorithm and self-adaptive inflation control logic, the non-corneal contact intraocular pressure can be measured. According to the intraocular pressure control system, the intraocular pressure measurement value is calculated and output to the upper computer by eliminating abnormal values and ensuring the stability of a pressure curve, so that the precision, the anti-interference performance and the adaptability of the intraocular pressure measurement data are improved, and the measurement error can be greatly reduced.

The utility model relates to the field of medical health, and the purpose is to provide an intraocular pressure measuring device to reduce the operation difficulty of user and improve measurement accuracy. The utility model discloses the technical scheme is: an intraocular pressure measuring device, characterized by: including the telescope cylinder with eyeshade, the rebound type pressure measuring module of setting in the telescope cylinder, the position adjusting module of connecting telescope cylinder and rebound type pressure measuring module, the controller of electric connection position adjusting module and rebound type pressure measuring module.

The invention discloses a digital contact lens intraocular pressure dynamic monitoring system integrated with a microsensor, and relates to the technical field of medical treatment. A microsensor module collects intraocular pressure indirect parameters and transmits the parameters to a data preprocessing module; the data preprocessing module performs standardization processing and time sliding window processing on the intraocular pressure indirect parameters to obtain historical multi-dimensional feature data and future multi-dimensional target data; the parameter screening module screens target parameters related to the intraocular pressure through correlation analysis; and the multi-task intraocular pressure prediction module outputs an intraocular pressure dynamic prediction result based on the target parameter. The invention provides a digital contact lens intraocular pressure monitoring system which integrates various microsensors, has a scientific parameter screening mechanism, is adaptive to time sequence dynamic prediction, and realizes dynamic prediction of contact lens intraocular pressure.

The invention belongs to the technical field of contact lens materials, and particularly relates to a 3D printing hydrogel material, a preparation method thereof and application of the 3D printing hydrogel material in preparation of intelligent contact lenses. The 3D printing hydrogel material is prepared from the following raw material components: hydroxyethyl methylacrylate, polyethylene glycol diacrylate, methacrylic acid-3-(trimethoxysilyl) propyl ester, PluronicF-127, poly (3, 4-ethylenedioxythiophene), poly (p-styrene sulfonate) and a photoinitiator. According to the 3D printing hydrogel material provided by the invention, the material can be directly formed into a contact lens matrix through high-precision 3D printing, so that a core material basis is provided for developing a next-generation comfortable and precise intelligent intraocular pressure monitoring contact lens which can be manufactured in a large-scale personalized manner, and the invention further provides a preparation method of the 3D printing hydrogel material. The hydrogel material disclosed by the invention is applied to 3D printed contact lenses, and the requirements of comfortable mechanical properties and the like of the contact lenses are met.

This invention belongs to the technical field of intelligent healthcare and relates to a dual-axis intelligent sensing method for dynamic measurement and health management of intraocular pressure (IOP). The method includes the following steps: Preliminary screening of fused physiological signals containing continuous IOP data and pressure state data within a synchronous time period; identification of the preliminary screening of fused physiological signals to generate an IOP event profile characterizing risk factors; analysis of the IOP event profile to generate a comprehensive intervention profile including coping strategies, with differentiated behavioral intervention instructions; execution of the comprehensive intervention profile to generate real-time feedback data on the intervention's effects; evaluation of the real-time feedback data on the intervention's effects to generate graded drug release decisions; and execution of the graded drug release decisions to generate proportionalized drug release control signals. This invention solves the problem that timed instillation cannot accurately match actual IOP peaks, potentially leading to drug waste and accumulated side effects when IOP is normal.

The invention provides a precise calibration device and calibration method for an FBG intraocular pressure sensor, and belongs to the technical field of medical detection instruments and optical fiber sensing. Comprising a fluid coupling base, and a three-dimensional micro-channel network is integrated in the fluid coupling base; the bionic eyeballs and the three-dimensional micro-channel network are communicated with each other to form a simulated aqueous humor chamber; the to-be-calibrated intraocular pressure sensing unit is arranged on the outer surface, away from the fluid coupling base, of the bionic eyeball and used for acquiring the pressure of the bionic eyeball; the fluid driving unit is used for providing fluid for the simulated aqueous humor chamber; the pressure detection unit is used for monitoring the internal pressure of the fluid coupling base; the FBG temperature sensing unit is used for extending into the intersection of each flow channel in the three-dimensional micro-flow channel network to obtain the temperature of fluid in the simulated aqueous humor chamber; and the control and processing terminal is used for acquiring the output of the intraocular pressure sensing unit, the FBG temperature sensing unit and the pressure detection unit and carrying out calibration through a built-in all-optical temperature compensation algorithm.

The application provides a dynamic adjustment micro-current stimulation and training method and system for ophthalmology. The application integrates various sensors through a wearable periocular device, collects physiological data such as corneal impedance, intraocular pressure signals, blinking behavior and visual evoked potential in real time, combines denoising, normalization, dimensionality reduction and multi-modal fusion processing, and constructs a standardized eye physiological state vector. The vector and incremental clustering are used to identify the micro-current stimulation tolerance inflection point, generate an individual safety upper limit initial value, combine a hierarchical fuzzy reasoning system and a dynamic comprehensive risk index, realize adaptive adjustment of the safety current limiting threshold, and finally smooth the micro-current output through a PID controller. The system can also update the model through cross-course memory data closed loop to improve the personalization and safety of the regulation. The application can dynamically adapt to individual physiological differences, effectively guarantee the biological safety of micro-current stimulation, and meet the needs of continuous and long-term adaptive fine intervention.

This invention discloses a closed-loop vision rehabilitation glasses system based on ultrasonic MEMS and AI-driven frequency modulation, belonging to the field of vision rehabilitation equipment technology. The system includes a glasses body (100), and an ultrasonic MEMS biosensing module (200), a visual stimulation module (300), an AI closed-loop control module (400), and a wireless communication module (130) integrated into the glasses body. The ultrasonic MEMS biosensing module is used to collect the ciliary muscle activity state of the user in a non-contact real-time manner. Its sensor array (210) is installed at a distance of ≤2mm from the face, and the light-shielding baffle (140) is tilted at 30°. The AI ​​closed-loop control module includes a data acquisition unit (410), an individualized frequency feature library construction unit (420), a real-time control unit (430), a visual health state spatial modeling unit (440), and a state guidance unit (450). It automatically identifies the user's optimal intervention frequency through multi-frequency stimulation scanning (6 / 8 / 10 / 12 / 15Hz) and a weighted comprehensive scoring method (weights: contraction speed 0.5 / accommodation amplitude 0.3 / intraocular pressure fluctuation 0.2), and dynamically adjusts visual stimulation based on real-time changes in ciliary muscle activity, forming a closed-loop rehabilitation circuit. A wireless communication module (130) enables data synchronization with an external terminal. This invention deeply integrates ultrasonic MEMS sensing, AI frequency optimization, and closed-loop control, offering advantages such as precise sensing, intelligent control, and significant rehabilitation effects.

The invention discloses a local network control electric cutting microsurgery platform which comprises a master console, a hook and a display screen are arranged above the master console, movable casters are arranged below the master console, an electric telescopic operating table is installed on the side wall of the master console, and a control panel is arranged on one side of the master console; the main console comprises a main control system, a wiring system, a power module system, an ultrasonic module system, an electric injection and suction system, an electric wave cutting system, an electrocoagulation control system, a silicone oil injection and suction pneumatic system, an intraocular pressure control system, an intraocular light source system and a silicone oil injection circuit system. In order to overcome the defect that no ophthalmology microscopic vitrectomy and super breast all-in-one machine operation platform exists in the market, the advanced network technology is applied, and a leading full-function and convenient closed-loop network control electric cutting microsurgery platform in the global ophthalmology field is provided.

The present invention provides an intraocular pressure measurement apparatus and a control method therefor. The intraocular pressure measurement apparatus comprises a measuring main body and a bearing main body. The measuring main body is configured to measure intraocular pressure and is mounted in the bearing main body. The bearing main body is configured to bear and support the measuring main body, and align an eye with a measuring end of the measuring main body. The intraocular pressure measurement apparatus of the present invention can directly measure intraocular pressure data by closing the eyelids without direct contact with the eyeballs, thereby avoiding the risk of eyeball infection. Moreover, the measuring main body is borne, supported and aligned by means of the bearing main body, which not only ensures the stability of the measurement structure, but also ensures the measurement precision. In addition, the measurement apparatus has a simple structure , a small size, and easy mobility and portability, and does not require accessories, facilitating instant measurement, and has easy operation, and high measurement efficiency.