142 results about "Flow diverter" patented technology

Neurovascular flow diverter and delivery systems, and methods of using the same are disclosed herein. The systems can include an introducer sheath, a catheter, a deployable flow diverter that can be contained in the introducer sheath or in the catheter, a core wire, and one or several deployment features coupled to the core wire and engaging the flow diverter. The deployment features can include one or more of a pusher, one or several friction bumps, one or several deployment coils, a claw mechanism, a self-expanding element, a supporting coil, a tip coil, and / or an atraumatic tip. One or more of the deployment features can be radiopaque.

Devices are provided with an internal dimension that can be reduced and increased in vivo. In one example, an interatrial shunt for placement at an atrial septum of a patient's heart includes a body. The body includes first and second regions coupled in fluid communication by a neck region. The body includes a shape-memory material. The body defines a passageway through the neck region for blood to flow between a first atrium and a second atrium. The first and second regions are superelastic at body temperature, and the neck region is malleable at body temperature. A flow area of the passageway through the neck region may be adjusted in vivo.

Systems and methods for delivering a device for regulating blood pressure across a patient's atrial septum are provided. The delivery apparatus may include a first catheter, a hub having one or more engagers disposed thereon, the one or more engagers configured to releasably engage with a first expandable end of the shunt in a contracted delivery state within a lumen of a sheath, and an second catheter extending through a center lumen of the first catheter and the hub, wherein the first catheter, the hub, and the second catheter are independently moveable relative to the sheath. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices also may be used to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

A downhole pumping system for subsea use is provided. The pumping system is designed such that all fluid conduits and electrical signal conduits are internalized within the pumping assembly. This design provides a substantially constant and elongated profile for the pumping assembly. The pumping assembly includes a housing containing the power assembly, a power actuator assembly operably linked to the production fluid assembly, and a central bore extending through the pumping assembly to provide fluid communication between the power assembly and a first end of the pumping assembly. The pumping system also includes a flow distributor / connector at the first end or the pump head for providing fluid communication between the pump head and a delivery system extending from the surface to the pumping system. The communicating fluids include a high pressure power hydraulic fluid, a low pressure discharge hydraulic fluid, and a pressurized production wellbore fluid.

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.

A device includes a pre-sample reservoir, an actuator mechanism, and a diverter. The pre-sample reservoir can be fluidically coupled to a delivery member to receive and isolate a predetermined volume of bodily-fluid withdrawn from a patient. The actuator mechanism is operably coupled to the pre-sample reservoir such that, when actuated, a negative pressure is formed in the pre-sample reservoir that urges the bodily-fluid to flow into the pre-sample reservoir. The diverter can selectively control fluid flow between the delivery member and the pre-sample reservoir. The diverter includes a flow control mechanism that defines a first fluid flow path and a second fluid flow path. The diverter is movable between a first configuration in which the bodily-fluid flows through the first fluid flow path to the pre-sample reservoir, and a second configuration in which the bodily-fluid flows through the second fluid flow path to a sample reservoir coupled to the diverter.

Disclosed are flow diverters including a self-expanding tubular member comprising a plurality of expandable cells having interconnected zig-zag rings and diagonal struts. The tubular member has a constrained configuration having a first outer diameter of at least 1.0 mm sized for delivery using a flow diverter delivery system and an expanded configuration having a second outer diameter larger than the first outer diameter. Related devices, delivery systems, and methods of using the devices and delivery systems for treating disease, particularly intracranial and cerebral aneurysms by deploying implantable expandable devices, are provided.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.

A method may involve creating a first opening in a right pulmonary artery and a second opening in a superior vena cava. A shunt may be percutaneously delivered into the first opening and the second opening. A stent may be percutaneously delivered into the superior vena cava adjacent to the shunt. The stent can comprise a covering to at least partially prevent flow of blood from the shunt through the stent and / or may be at least partially flexible to allow the stent to bend away from walls of the superior vena cava in response to inflow of blood through the shunt. The stent may be sized to seal against the superior vena cava at a first end and a second end of the stent to trap blood between the stent and the walls of the superior vena cava.

The invention provides a soil reducing inorganic sulfide continuous extraction device and a use method thereof. The extraction device comprises a brown reaction bottle, a first sealing bottle plug is arranged at a bottle opening of the brown reaction bottle, and a gas replacement needle, a sample injection needle and a liquid replacement needle are arranged on the first sealing bottle plug; the reagent deoxidizing bottle is connected with the sample injection needle through a first liquid flow divider and a first multi-channel injection pump; a second sealing bottle plug is arranged at a bottle opening of the reagent deoxidizing bottle, a first needle tube, a second needle tube and a third needle tube are respectively arranged on the second sealing bottle plug, a needle seat of the second needle tube is connected with a second two-way valve, the second two-way valve is connected with a first liquid diverter, the first liquid diverter is connected with a first multi-channel injection pump, and the second liquid diverter is connected with a second multi-channel injection pump. A channel of the first multi-channel injection pump is connected with an eighth two-way valve on the sample injection needle seat; and the absorption liquid deoxidizing bottle is connected with the liquid changing needle through a second liquid diverter and a second multi-channel injection pump. The detection efficiency and stability of the soil reducing inorganic sulfide are improved.

An apparatus for shunting blood includes a flow-indication chamber shaped to define an entry port and an exit port, and one or more moveable objects disposed within the flow-indication chamber and configured to move in response to a flowing of the blood from the entry port to the exit port. At least a portion of a wall of the flow-indication chamber is transparent so as to expose the moveable objects to sight. Other embodiments are also described.

The present invention relates to a bore access spool assembly comprising a housing (2) having a longitudinal axis, an upper end (3) of the housing being configured for connection to a riser, a lower end (4) of the housing being configured for connection to a subsea well assembly. The housing further comprises an upper bore (5) located at the upper end, and a plurality of lower bores (6, 6a) located at the lower end, a chamber (7) extending along the longitudinal axis linking the upper and lower bores. A diverter sleeve (11) is provided for introduction into the housing chamber (7) through the upper bore (5), the diverter sleeve (11) being open at its upper end to allow access into a sleeve interior from the upper bore (5), and having an angled kick surface (17) at a lower end of its interior, the diverter sleeve (11) and housing (2) having respective guide formations. The diverter sleeve (11) is configured to be received within the chamber (7) and guided into position through interaction of the guide formations to a deployed state to block a first one (6a) of the plurality of lower bores (6a, 6b), and to divert communication of the upper bore (5) instead to be with a second one (6b) of the plurality of bores.

A shunt for treating glaucoma that includes a silicone rubber duct for diverting aqueous humor from a chamber of a patient's eye and a fixation body frictionally located on the duct in an arrangement permitting sliding displacement of the fixation body, for fixing and sealing the duct within scleral tissue surrounding the eye. The duct has a rigid proximal portion having a proximal end and a deformable distal portion locatable in the scleral channel and having a distal end. The distal portion is severable, allowing a surgeon to cut the distal portion to a desired length corresponding to the anatomical dimensions of the patient's eye and a required bleb position. The proximal portion has a capillary lumen having a diameter which is smaller than the diameter of a lumen of the distal portion, thereby reducing a flow rate of aqueous humor along the capillary lumen.

Disclosed are flow diverters including a self-expanding tubular member comprising a plurality of expandable cells having interconnected zig-zag rings and diagonal struts. The tubular member has a constrained configuration having a first outer diameter of at least 1.0 mm sized for delivery using a flow diverter delivery system and an expanded configuration having a second outer diameter larger than the first outer diameter. Related devices, delivery systems, and methods of using the devices and delivery systems for treating disease, particularly intracranial and cerebral aneurysms by deploying implantable expandable devices, are provided.

Disclosed are flow diverters including a self-expanding tubular member comprising a plurality of expandable cells having interconnected zig-zag rings and diagonal struts. The tubular member has a constrained configuration having a first outer diameter of at least 1.0 mm sized for delivery using a flow diverter delivery system and an expanded configuration having a second outer diameter larger than the first outer diameter. Related devices, delivery systems, and methods of using the devices and delivery systems for treating disease, particularly intracranial and cerebral aneurysms by deploying implantable expandable devices, are provided.

The present technology is generally directed to interatrial shunting systems and associated devices and methods. For example, a system configured in accordance with embodiments of the present technology can include a shunting element implantable into a patient at or adjacent a septal wall. The shunting element can have a lumen that fluidly connects a left atrium and a right atrium of the patient to facilitate blood flow therebetween when the shunting element is implanted. In some embodiments, the system further includes a flow control element to selectively control blood flow between the left atrium and the right atrium.

A fluidic system includes a cartridge having a brine subsystem, a contrast agent subsystem, and a vacuum subsystem. The fluidic system further includes a diverter and a first set of conduits coupled to the cartridge and the diverter, the first set of conduits having a single saline channel, a single contrast agent channel, and a single vacuum channel. The fluidic system further includes two or more hub assemblies, at least one of the two or more hub assemblies configured to have a third saline flow path, a third contrast agent flow path, and a third vacuum flow path, the two or more hub assemblies are coupled to one another to provide saline, contrast agent, and vacuum to a lumen of a catheter coupled to at least one of the two or more hub assemblies. The fluid system further includes a second tubing set having a plurality of tubing sets, each tubing set coupled to the diverter and one of the two or more hub assemblies.

Interventional procedures on the carotid arteries are performed through a transcervical access while retrograde blood flow is established from the internal carotid artery to a venous or external location. A system for use in accessing and treating a carotid artery includes an arterial access device, a shunt fluidly connected to the arterial access device, and a flow control assembly coupled to the shunt and adapted to regulate blood flow through the shunt between at least a first blood flow state and at least a second blood flow state. The flow control assembly includes one or more components that interact with the blood flow through the shunt.

A cardiac microperfusion device is disclosed that includes an integrated flow restrictor and a diverter from the left atrium to modulate flow within the blood vessel, particularly flow within the coronary sinus. Related methods and systems are also disclosed.

A shunt for treating glaucoma comprises a silicone rubber duct for diverting aqueous humor from a chamber of a patient's eye and a fixation body frictionally located on the duct in an arrangement permitting sliding displacement of the fixation body, for fixing and sealing the duct within scleral tissue surrounding the eye. The duct has a rigid proximal portion having a proximal end and a deformable distal portion locatable in the scleral channel and having a distal end. The distal portion is severable, allowing a surgeon to cut the distal portion to a desired length corresponding to the anatomical dimensions of the patient's eye and a required bleb position. The proximal portion has a capillary lumen having a diameter which is smaller than a diameter of a lumen of the distal portion, thereby reducing a flow rate of aqueous humor along the capillary lumen.

An endoscope with a fluid flow diverter is provided. The endoscope includes endoscope body and a tool port cap assembly defining an opening into an instrument path through the body of the endoscope for insertion of an instrument. The tool port cap assembly comprises an upper tool port portion, a lower tool port portion, at least one fluid flow channel, and a diverter seal disposed between the upper tool port portion and the lower tool port portion. The diverter seal is arranged to direct fluid flowing antegrade through the instrument path (i.e., along a distal-to-proximal direction) into the fluid flow channel. Further disclosed are integrated irrigation channels, both primary and auxiliary, incorporated into the endoscope handle.

The present technology relates to adjustable shunting systems and methods. In some embodiments, the present technology includes an adjustable shunting system that includes a drainage element having an inflow portion configured for placement within a patient. The system can also include a flow control assembly having a gating element operably coupled to the outflow portion of the drainage element. The flow control assembly can further include a first actuation element and a second actuation element coupled to the gating element. The first and second actuation elements can be configured to selectively move the gating element relative to the outflow portion to control an amount of fluid flow therethrough. The first and second actuation elements can each extend less than entirely around a perimeter of the drainage element.

The utility model discloses a diverter and refrigeration equipment, including diverting main pipe and a plurality of branches communicated with the diverting main pipe, the diverting main pipe is provided with a mixing chamber, the mixing chamber of the diverting main pipe is provided with at least two stirring impellers, the stirring impellers rotate under the impact of refrigerant, and the stirring impellers rotate under the impact of refrigerant. And the rotation directions of the at least two stirring impellers are opposite. The stirring impeller is arranged in the flow dividing main pipe, when a refrigerant passes through the stirring impeller, pressure generated by flowing of the refrigerant enables the stirring impeller to rotate, when the stirring impeller rotates, the refrigerant is also driven to flow spirally, and gas and liquid divided by branches in all directions are equal through striking and flow guiding of the stirring impeller, so that the flow dividing efficiency is improved. And the problem of non-uniform shunting is solved.

Endovascular assemblies may include a catheter, a shunt, and a wire. The shunt includes a frame and a liner secured about the frame. The wire extends through the catheter and is coupled to the shunt. The shunt is configured to move between a collapsed configuration and a radially expanded configuration in response to movement of the wire. Endovascular assemblies may be used to shunt a vessel.

The dialysis catheter replacement connector comprises a flow divider, a first catheter, a second catheter and a third catheter, one end of the first catheter and one end of the second catheter are communicated with one end of the third catheter through the flow divider, and the other end of the first catheter is provided with a one-way valve used for inserting a guide wire. The other end of the second catheter is provided with a second catheter connector used for being connected with a radiography syringe, and the third catheter is provided with a third catheter connector used for being connected with the shearing opening of the built-in catheter. According to the dialysis catheter replacement tube connector, radiography and placement of a guide wire into the body of a patient can be conducted at the same time, operation of a doctor is facilitated, operation risks are reduced, and medical safety is improved; the catheter infection probability in the catheter replacement process can be further reduced; the blood loss of a patient can be reduced, the surgical tolerance of the patient is improved, and the postoperative recovery time is prolonged; the medical experience of the patient can be improved, and the satisfaction degree of the patient is improved.

The invention relates to a medical device, in particular a stent or flow diverter, comprising a mesh structure, in particular a self-expandable mesh structure, wherein the mesh structure comprises at least one mesh structure element (10) which is encased, in particular in its entirety, by a nanostructured coating formed from fibrin nanofibres (11, 12), wherein the nanostructured coating has a first layer (L1) which forms a matrix, in particular a felt-like or fleece-like matrix, of interconnected fibrin fibres (11), wherein some fibrin fibres (12) protrude freely beyond the first layer (L1) and form a second layer (L2) comprising a single-fibre structure, in particular a pile-like single-fibre structure, and wherein the nanostructured coating additionally contains a polynucleic acid-based or peptide-base KLF5 inhibitor that is integrated into the first layer (L1) and / or the second layer (L2).

A valve assembly includes a housing which has a liquid inlet and a liquid outlet, a cover affixed to the housing, a flow regulating assembly located in the housing, and an anti-cavitation flow diverter mounted in the housing. The anti-cavitation flow diverter includes an outer wall that surrounds an inner hollow portion. Sets of flow apertures are formed through the wall thickness of the outer wall. Each flow aperture is open to the inner hollow portion and extends at an angle along a non-radial path through the outer wall. Flows of liquid flowing through each set of the flow apertures impinge upon each other at meeting points which are spaced from inner surfaces of the housing.

To provide a shunt system and a method with tissue growth prevention.SOLUTION: A shunt comprises a central flow portion configured to fit at least partially within an opening in a tissue wall. The tissue wall is situated between a first anatomical chamber and a second anatomical chamber and the opening represents a blood flow path between the first anatomical chamber and the second anatomical chamber. The central flow portion is further configured to maintain the blood flow path from the first anatomical chamber to the second anatomical chamber. The shunt further comprises a barrier configured to alter growth of tissue around the shunt.SELECTED DRAWING: Figure 4

The invention relates to a medical device, in particular a stent or flow diverter, comprising a mesh structure, preferably a self-expanding mesh structure, wherein the mesh structure comprises at least one mesh structure element (10) which is encased, in particular in its entirety, by a nanostructured coating formed from fibrin nanofibres (11, 12), wherein the nanostructured coating has a first layer (L1) which forms a matrix, in particular a felt-like or fleece-like matrix, of interconnected fibrin fibres (11), wherein some fibrin fibres (12) protrude freely beyond the first layer (L1) and form a second layer (L2) comprising a single-fibre structure, in particular a pile-like single-fibre structure, and wherein the nanostructured coating additionally contains retinoic acid and / or a synthetic retinoid, which is integrated into the first layer (L1) and / or the second layer (L2).