94 results about "Right atrium" patented technology

A method is provided that includes inserting an inflow cannula of a left ventricular assist device (LVAD) of a LVAD system into a left chamber of a heart of a patient transeptally via a right atrium and a superior vena cava (SVC). An outflow cannula of the LVAD is coupled to a left subclavian artery or a left axillary artery. Other embodiments are also described.

Systems and methods for implanting a shunt for regulating blood pressure between a patient's left and right atria are provided. The shunt comprises an anchor having a neck region, first and second end regions, and a conduit affixed with the anchor formed of a biocompatible material that is resistant to transmural and translation tissue ingrowth and that reduces a risk of paradoxical embolism. The shunt may be advanced through the sheath until the first region protrudes from the sheath and self-expands within the left atrium. The shunt and the sheath may then be retracted until the first region contacts the left side of the atrial septum. The sheath may further be retracted until the counterforce exerted by shunt tension on the atrial septum overcomes the friction of the retained portions of the shunt such that the second region is exposed from the sheath and self-expands within the second atrium.

The invention provides an automatic counting method and system for ultrasonic microbubbles in right heart acoustic radiography. The method comprises the following steps: acquiring a cardiac radiography image of a patient through high-resolution ultrasonic equipment; extracting a region of interest of the cardiac angiography image based on the cardiac vascular structure, and performing image registration operation on the cardiac angiography image by taking the region of interest as a reference point to obtain a registered image; carrying out pixel-by-pixel addition on two frames of pulse images with opposite phases in the registered image to obtain an enhanced image; determining the high-echo bright spots in the enhanced image as suspected microbubbles, and performing denoising processing according to the feature similarity to obtain real microbubbles; judging pathological conditions according to whether real microbubbles exist in the left atrium or not; if the real microbubbles exist in the left atrium, grading the abnormal blood flow according to the change data of the microbubbles in the left atrium and the right atrium. According to the method, through high-precision image registration, multi-modal feature analysis and dynamic parameter fusion technologies, the microbubble detection accuracy is improved, and quantitative grading of pathological conditions is achieved.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum, and a drug-eluting biodegradable material that biodegrades over time to release a drug that limits tissue overgrowth. The inventive device also may include a biodegradable material that biodegrades to offset flow changes caused by tissue overgrowth. The inventive device may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits.

A device for regulating blood pressure between a patient's left atrium and right atrium comprises an hourglass-shaped stent comprising a neck region and first and second flared end regions, the neck region disposed between the first and second end regions and configured to engage the fossa ovalis of the patient's atrial septum; and a one-way tissue valve coupled to the first flared end region and configured to shunt blood from the left atrium to the right atrium when blood pressure in the left atrium exceeds blood pressure in the right atrium. The inventive devices may reduce left atrial pressure and left ventricular end diastolic pressure, and may increase cardiac output, increase ejection fraction, relieve pulmonary congestion, and lower pulmonary artery pressure, among other benefits. The inventive devices may be used, for example, to treat subjects having heart failure, pulmonary congestion, or myocardial infarction, among other pathologies.

An implantable lead for use with an implantable medical device (IMD) includes a tubular lead body having a proximal portion including a proximal end, a distal portion including a distal end opposite the proximal end, and an intermediate portion between the proximal portion and the distal portion. A helical electrode extends distally from the distal end of the tubular lead body. At least one atrial electrode is disposed in the intermediate portion of the tubular lead body. At least one electrical conductor extends through the tubular lead body and is mechanically and electrically coupled to the helical electrode and the at least one atrial electrode. The intermediate portion may have a pre-formed bend configured to urge the at least one atrial electrode against a surface of the right atrium when the lead is implanted. A distal pre-formed bend located in the distal portion of the tubular lead body may be configured to bias a plurality of pacing / sensing electrodes towards a surface of a right ventricle. A distal pre-formed bend located in the distal portion of the tubular lead body may be configured to bias the helical electrode and at least one pacing / sensing against a surface of a right ventricle.

The utility model relates to an adult simulation load device for online calibration of an extracorporeal membrane oxygenation system. The system comprises a left ventricular artery system simulation box, a right atrial vein system simulation box, a resistance device, a V-A ECMO treatment mode artery perfusion cannula, a V-V ECMO treatment mode vein perfusion cannula, a vein drainage cannula, a bottom plate, a right atrial vein system simulation box hydraulic monitoring sensor, a left ventricular artery system simulation box hydraulic monitoring sensor and a manual pressure release valve. And a ball valve pressurizing device and a vertical partition plate. The left ventricular artery system simulation box, the resistance device and the right atrial vein system simulation box are sequentially connected through pipelines. The device is simple in structure, convenient and practical to operate and capable of accurately simulating the blood volume of a patient, the pressure difference between a venous system and an arterial system and the resistance of a blood circulation system when an adult patient adopts a V-A ECMO treatment mode and a V-V ECMO treatment mode respectively, and has practical value; calibration data has clinical guiding significance, the measurement accuracy of key parameters of equipment is effectively guaranteed, and clinical risks are reduced.

The present disclosure relates to a device assembly and a method for treating heart failure by normalizing elevated blood pressure in the left atrium of a heart of a mammal. Disclosed herein is a transcatheter interatrial septum excision device assembly configured to create a sized interatrial aperture between the right and left atria of a heart for the relief of elevated left atrial pressure. The device assembly comprises a delivery catheter, a tissue stabilizer attached to a first catheter having a central lumen and a penetrating tip that permits passage of a guidewire, and a cutter attached to a second catheter having a central lumen that permits passage of the first catheter. Alternative configurations comprise a (third) catheter having a central lumen that permits passage of the aforementioned components to and from the right atrium, a tissue retention mechanism and an optional coaxial alignment mechanism.

An arrhythmia type inference device includes: an obtaining section that obtains a target signal waveform indicating a time-series change in the area of a region, which is at least one of a left atrium, a left ventricle, a right atrium, and a right ventricle, the target signal waveform being generated by analyzing an image of a heart of a target subject; and an inference section that infers the type of tachyarrhythmia suffered by the target subject based on the shape of the target signal waveform having a frequency in a frequency band higher than a reference frequency band predetermined as a normal range. This allows the arrhythmia type inference device to accurately infer the type of tachyarrhythmia from the image obtained by image-capturing of the heart.

The invention discloses a hemodynamic monitoring system and a control method for an intermittent occlusion balloon catheter. The monitoring system comprises a blood flow pressure measurement module, a cardiac displacement measurement module, a thrombus monitoring module and an infusion pump control module. The control method comprises the steps that a right atrium and vena cava pressure threshold value is set, the size of a balloon is controlled and adjusted through an infusion pump, the relation between blood flow pressure and the pressure threshold value is continuously monitored, and then the expansion size and time of the balloon are fed back and adjusted; based on an automatic cold solution suction-discharge module, the cardiac displacement change is indirectly measured; in the treatment process, parameter changes such as cardiac displacement, right atrium pressure and vena cava pressure of a patient are measured, and whether the patient recovers hemodynamics or not is monitored, and safe machine withdrawal conditions are met; and the thrombus risk condition near the balloon is analyzed through the thrombus monitoring module. The size and time of the balloon are adjusted through pressure feedback, and the infusion precision is improved; and machine withdrawal judgment conditions are set, so that the treatment effect of the patient is improved.

The present technology is generally directed to interatrial shunting systems and associated devices and methods. For example, a system configured in accordance with embodiments of the present technology can include a shunting element implantable into a patient at or adjacent a septal wall. The shunting element can have a lumen that fluidly connects a left atrium and a right atrium of the patient to facilitate blood flow therebetween when the shunting element is implanted. In some embodiments, the system further includes a flow control element to selectively control blood flow between the left atrium and the right atrium.

An ultrasound imaging and backscatter system includes an ICE ultrasound catheter having an ultrasound pMUT transducer array disposed within a distal end of the ultrasound catheter and including a plurality of transducer array elements disposed on a substrate. One end of the catheter shaft is connected to the handle assembly and the other end is connected to the ultrasonic transducer array. The catheter shaft accommodates an electronic flexible cable in communication with the signal trace and directs each of the plurality of transducer array elements to transmit and receive an ultrasound beam, receives at least one signal from the plurality of transducer array elements, and constructs at least one image characterizing one or more tissue components of the scanned object. An ultrasound imaging system is used to measure tissue thickness, tissue scar, and lesion assessment for left atrium, right atrium, left ventricle, and right ventricle tissue wall characteristics and other intracardiac tissue anomalies.

A method of sensing a physiological parameter involves advancing a delivery catheter to a right atrium of a heart of a patient via a transcatheter access path, advancing the delivery catheter through an atrial septal wall into a left atrium of the heart, deploying a distal anchor of a sensor implant device from the delivery catheter, anchoring the distal anchor of the sensor implant device to a first pulmonary vein, withdrawing the delivery catheter from the first pulmonary vein, thereby exposing at least a portion of a sensor module of the sensor implant device in the left atrium, deploying a proximal anchor of the sensor implant device from the delivery system, anchoring the proximal anchor of the sensor implant device to a second pulmonary vein, and withdrawing the delivery catheter from the heart.

A method and devices for relieving pressure in the left atrium of a patient's heart is disclosed. The method includes using an ablative catheter in a minimally invasive procedure to prepare an opening from the coronary sinus into a left atrium of the patient's heart. Once the opening is prepared, the opening may be enlarged by a technique such as expanding a balloon within the opening. A stent is then placed within the coronary sinus of the patient, with a transverse portion expanding within the opening, allowing blood to flow from the left atrium to the coronary sinus and then to the right atrium. Pressure within the left atrium is thus relieved.

A right cardiac assisting device to be percutaneously implanted inside a patient's heart, including an inlet, an outlet, a pump connecting the inlet to the outlet, and being designed to be located inside the right atrium or vena cava of the patient. The assisting device includes at least one support element configured to be secured to a first membrane of the patient's heart by passing through the first membrane, the first membrane separating the right atrium from the pulmonary artery of the patient's by passing through it. The support element tightly cooperates with the outlet to immobilize the pump, the inlet and the outlet inside the patient's heart and enable the patient's blood flow to be driven from the inlet to the outlet through the first membrane.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

The invention relates to the technical field of internal medicine operations, and discloses an ectopic implantation valve stent system for treating tricuspid regurgitation, which comprises a right atrium and a right ventricle fixedly connected to the right atrium; the tricuspid valve is fixedly connected between the right atrium and the right ventricle; the cannula assembly is connected into the tricuspid valve in a sliding mode; the supporting assembly is fixedly connected to the right atrium; the bracket assembly is fixedly connected to the supporting assembly; the valve assembly is fixedly connected to the supporting assembly; one part of the supporting assembly is fixedly connected to the right atrium, and the other part of the supporting assembly is fixedly connected to the tricuspid valve. Liquid medicine is injected into the curing tube through the sealing nozzle through the injection tube, after the liquid medicine and the curing liquid are mixed, the curing liquid is cured, meanwhile, barbed nails on the fixing plate layer are used for puncturing the root of the tricuspid valve for further fixing, the stent assembly and the valve assembly are not prone to falling off after being installed, the service time is longer, and the fixing effect is better. Patients do not need to have mental stress due to the falling risk of the support assembly.

Mitral regurgitation can be reduced by creating one passageway between the right atrium and left ventricle in a portion of the tricuspid annulus just above the ventricular septum and another passageway through the outer wall of the left ventricle near at least one of the left ventricular papillary muscles. A support rod is positioned in the right atrium in contact with the septal portion of the tricuspid annulus, and a support plate is positioned adjacent to the second passageway and against the outer wall of the left ventricle. The support plate is pulled toward the support rod using a tether that extends between the first support plate and the support rod, passes through both passageways, and is under tension. The tension in the tether moves the root of the tendon closer to the mitral valve, which reduces mitral regurgitation.

The invention discloses application of scopalactone in treatment of pulmonary arterial hypertension, and relates to the technical field of medicinal chemistry. The scoparone is applied to preparation of the medicine for treating pulmonary arterial hypertension. The medicine comprises scopalactone, a pharmaceutically acceptable carrier, a diluent and an excipient, the medicine further comprises other medicines for treating the pulmonary arterial hypertension, and the other medicines for treating the pulmonary arterial hypertension are selected from a prostacyclin medicine, an endothelin receptor antagonist and a phosphodiesterase-5 inhibitor. The scopalactone is applied to preparation of the medicine for treating pulmonary arterial hypertension, right heart insufficiency caused by hypoxia can be remarkably reversed, and the right heart function is effectively improved by reducing the transverse diameter of the right ventricle and the transverse diameter of the right atrium and improving the indexes such as tricuspid valve ring plane contraction displacement; the average pulmonary arterial pressure and right ventricular systolic pressure can be obviously reduced, and hemodynamic parameters are improved; the area and thickness of a blood vessel wall can be remarkably reduced, the blood vessel structure is improved, and pulmonary arteriole reconstruction is relieved.

A system for improving the function of a defective heart includes a tubular membrane, a replacement valve, a set of one or more inlets, and a set of one or more outlets. The tubular membrane encompasses (i) a first chamber of the system, shaped to conform to an interior region of a right atrium of the heart, and (ii) a second chamber of the system, shaped to conform to an interior region of a right ventricle of the heart. The replacement valve is configured to separate the first chamber from the second chamber, and has leaflets for providing flow in only one direction. The one or more inlets connect the first chamber with a first portion of cardiovascular anatomy, and the one or more outlets connect the second chamber with a second portion of cardiovascular anatomy.

Apparatuses and methods for performing transseptal extracorporeal membrane oxygenation are disclosed. The method may include puncturing a septum between the right atrium and the left atrium and advancing a catheter system through the puncture and into the aorta. The catheter system may include coaxially arranged and independently moveable venous and arterial sheaths having independently positionable openings for removing blood from the patient and for returning oxygenated blood to the patient, e.g., within the aorta.

This invention discloses a method for blood collection from the right adrenal vein, belonging to the field of venous blood collection methods. The method includes the following steps: providing an RH catheter, which is a dedicated catheter for hepatic artery angiography, with its tip bent 180° to form a plane, and its tip bent perpendicularly to this plane at 90°; inserting the RH catheter through the right femoral vein, advancing it to form a loop in the right atrium, and then pulling it back to the inferior vena cava; adjusting the direction of the RH catheter, using its three-dimensional curved portion to hook onto the opening of the right adrenal vein, thereby inserting it into the right adrenal vein; injecting contrast agent to confirm that the tip of the RH catheter is located within the right adrenal vein; collecting a blood sample from the right adrenal vein through the RH catheter, with a single blood sample volume of 12 ml; after blood collection, performing post-confirmation angiography to verify whether the RH catheter is located within the target vein. This invention can significantly improve the success rate of right-side catheter insertion and blood collection efficiency, while reducing costs and facilitating operation.

The invention discloses an interventional valve ring device and an interventional valve device. The interventional valve ring device and the interventional valve device can be used for mitral valve and tricuspid valve lesions. The interventional valve ring device is mainly composed of a valve ring, a valve ring conveying system, a fixing nail and a fixing nail conveying system. The interventional valve is mainly composed of a fixing support, a supporting support, a supporting support covering film and valve leaflets. The interventional valve ring and the interventional valve enter the heart through the interventional delivery system and can pass through the apex of the heart, the femoral vein, the jugular vein or the subclavian vein, the right atrium or the left atrium. The interventional valve is fixed in the interventional valve ring, and a minimally invasive, safe and effective treatment method can be provided for a patient.

Systems and methods are described for determining a fluid congestion status of a subject, the method being carried out by at least one processor executing operations comprising: receiving an initial right atrial pressure for the subject; causing, over a time period, a vessel occlusion device to perform an occlusion cycle to change blood flow resistance in a blood vessel of the subject; receiving monitored readings for a right atrial pressure response to the changed blood flow resistance in the blood vessel over the time period; and determining, for the subject and based on the readings representing the right atrial pressure response, a fluid congestion status associated with a heart of the subject.

The invention relates to a cardiovascular implant device for directing flow. A cardiovascular implant device includes an annular body, one or more anchoring members, and a diversion assembly. The annular body includes a central flow tube extending from an inflow end to an outflow end and a flow path extending through the central flow tube. The one or more anchoring members extend outwardly from the annular body and are configured to secure the cardiovascular implant device to a tissue wall. The diversion assembly is positioned to align blood flow out of the cardiovascular implant device with a natural flow pattern of blood in the right atrium such that the blood flow out of the cardiovascular implant device is combined with the natural flow pattern of blood in the right atrium.

Methods, systems, and computer-readable medium for determining a systemic vascular resistance (SVR), by receiving a systolic blood pressure (SBP) and a diastolic blood pressure (DBP) from one or more blood pressure devices, receiving a first bioimpedance from a first electrode and a second bioimpedance from a second electrode, determining a stroke volume based on a difference between the first bioimpedance and the second bioimpedance, determining a mean arterial pressure (MAP) based on the SBP and the DBP, receiving a heart rate, determining a cardiac output based on the heart rate and the stroke volume, determining a first value based on a right atrial pressure (RAP) or central venous pressure (CVP) and the map, determining a second value based on the first value and the cardiac output, and determining a SVR based on the second value and a factor.

An apparatus, system, and method for creating a shunt between a right atrium and a left atrium of a patient's heart. An apparatus includes a shielding structure, a tube proximal to the shielding structure, and an actuating mechanism at a proximal end of the tube. The tube is configured to pass through a lumen of a steerable catheter. The actuating mechanism is for deploying the shielding structure through the tube. The shielding structure is configured for passing through an opening in an atrial septum from the right atrium to the left atrium, and for being retracted in a proximal direction to contact the atrial septum for shielding a proximity of the opening from blood flow in the left atrium to facilitate cryoablation of the opening from the right atrium.

The present technology is directed to adjustable interatrial shunting systems that selectively control blood flow between the left atrium and the right atrium of a patient. The adjustable interatrial devices include a shunting element having an outer surface configured to engage native tissue and an inner surface defining a lumen that enables blood to flow from the left atrium to the right atrium when the system is deployed across the septal wall. The systems can include an actuation assembly for selectively adjusting a geometry of the lumen and / or a geometry of a lumen orifice to control the flow of blood through the lumen.

The application discloses a kind of near-field coherent heart radio frequency sensing method and system based on code division multiple access, comprising: 4-way frequency f synchronous baseband signal is configured, 4-way synchronous chip is configured, synchronous baseband signal is multiplied with corresponding synchronous chip to modulate, and 4-way digital baseband signal is obtained;4-way digital baseband signal is handled to obtain 4-way heart measurement signal;4-way heart measurement signal is respectively transmitted to corresponding antenna by radio frequency transceiver and is emitted;The antenna is respectively arranged in left ventricle, left atrium, right ventricle, right atrium;Antenna receives reflected signal, and is recorded as heart sensing signal;Heart sensing signal is transmitted to radio frequency transceiver, and after processing, the baseband signal containing heart chamber beat information is obtained;The baseband signal containing heart chamber beat information is multiplied with corresponding synchronous chip to demodulate, band-pass filter, and the demodulation signal corresponding to heart chamber beat information is obtained respectively.

The present teaching provides devices and methods for treating heart disease by normalizing elevated blood pressure in the left and right atria of a heart. Various embodiments of the devices allow left-to-right blood flow through their flow elements. The flow element of the device is designed to self-adjust the amount of blood flow in response to the left atrial pressure fluctuation.