32 results about "Cardiac stimulation" patented technology

Systems, devices, and methods for delivering pulsed electric field ablation energy to endocardial tissue are disclosed, wherein the system includes a pulsed waveform signal generator for medical ablation therapy and an endocardial ablation device including at least one electrode for delivering ablation pulses to tissue. The signal generator can deliver voltage pulses to the ablation device in the form of a pulsed waveform. The system can include a cardiac stimulator for generating a pacing signal and for delivering a pulsed waveform in sequence in synchronization with the pacing signal.

The module includes: a conversion stage (110) receiving as input a sampled activity signal (ACTk) representative of the instantaneous activity of the patient and delivering as output a first target value (Xk) by application of a predetermined activity / heart rate function (F(ACT)); a recursive digital low-pass filter (130) calculating over a predetermined time a moving average of the first target value (Xk) delivered by the conversion stage (110) and giving as output a second target value (Zk); and a combiner stage (140) receiving as input the first target value (Xk) and the second target HR value (Zk) delivered by the first digital low-pass filtering stage (130), determining the maximum of the two target values ​​and giving as output the setpoint value (HRk) to control the stimulation frequency to the patient's activity.

The invention relates to a device for assisting in the handling and implantation of at least one electrode support(s) for a cardiac device, in particular a cardiac pacing device, said at least one electrode support(s) comprising a distal end and a proximal end, the proximal end comprising at least one connector configured to be in electrical connection with at least one portion of the distal end, characterized in that said device comprises: - a body, preferably one-piece, configured to cover at least one portion of said at least one connector, - at least one receiving portion for a means of temporary electrical connection, such as a crocodile clip, said at least one receiving portion being electrically conductive, - at least one connection element in electrical connection with said at least one receiving portion, said at least one connection element being in controlled tangential contact with said at least one connector.The invention also relates to the use of this device for the transfer of electrical signals into or from a cardiac stimulation device electrode, as well as a method for assembling this device.

Esophageal intubation assemblies, esophageal cardiac stimulation and gastric decompression assemblies, and methods for using and making the same are provided.

The hybrid stimulation system is an electrical stimulation system serves to delivered an electrical stimulation impulse to the heart (human or animal heart) , using a combination of internal (intravascular) and external (body surface) electrodes, the hybrid electrical stimulation system can be used for pacing of the heart during slow heart beat (bradycardia), or shocking the heart during fast heart beat (Tachycardia) , or to terminate fast abnormal heart beat (tachy-arrhythmia) by means of override pacing (Anti-tachycardia pacing). This hybrid system can be used and introduced into the body without the need for imaging guidance such as fluoroscopy or echocardiography to insert the internal component, and does not require direct contact between the internal pacing wire and the myocardium (internal heart surface).

The invention relates to an implantable medical stimulation device (1) for stimulating an atrium (RA) of a patient's heart (H), comprising a generator device (12) with a processing circuitry (120) configured to perform a rate-adaptive cardiac stimulation in which a paced heart rate is adjusted based on a load state of the patient. The processing circuitry (120) is further configured to obtain a momentary impedance curve (ΔZ1) indicative of a measured impedance during a cardiac cycle, to compare said momentary impedance curve (ΔZ1) to a stored reference curve (ΔZrefRest) indicative of a reference impedance curve and to perform an adaption of the paced heart rate based on the comparison of the momentary impedance curve (ΔZ1) to the stored reference curve (ΔZrefRest). The processing circuitry (120) is furthermore configured to obtain said momentary impedance curve (ΔZ1) using at least one ventricular electrode pole (102).

The invention relates to a screwing stylet for improving torque transfer from a physician's hand to a lead tip (e.g., helix) of a lead device. A lead tip is provided to facilitate handling and a screwdriver functionality of the screwing stylet is provided to improve torque transfer to the lead tip of the lead device for better control of a puncturing process. The screwing stylet can be engaged directly with the tip of the lead device, thereby allowing a direct and efficient torque transfer to the fixed helix at the tip.

Existing clinically adopted epicardial pacing leads mostly rely on surgical suturing or insertion of electrodes to the heart tissue. However, these approaches can cause tissue trauma during application and / or retrieval of the implants, potentially causing detrimental complications such as bleeding, tissue damage, and / or device failure. The present invention provides a bioadhesive epicardial pacing lead for atraumatic epicardial monitoring and stimulation of the heart in vivo to overcome the limitations of existing bioelectronic implants. The bioadhesive pacing lead is composed of an insulation layer, a conductive bioadhesive interface, a built-in reservoir, an electrode lead wire, and a fluidic channel. The bioadhesive pacing lead shows robust mechanical and electrical properties, biocompatibility, continuous epicardial monitoring and pacing capability, and rapid on-demand atraumatic employment and removal.

Various configurations of systems that employ leadless electrodes to provide pacing therapy are provided. In one example, a system that provides multiple sites for pacing of myocardium of a heart includes wireless pacing electrode assemblies that are implantable at sites proximate the myocardium using a percutaneous, transluminal, catheter delivery system. Also disclosed are various configurations of such systems, wireless electrode assemblies, and delivery catheters for delivering and implanting the electrode assemblies.

Methods and systems for dynamically modifying pacing timing and backup pacing delivery in cardiac stimulation devices include applying pacing impulses, measuring corresponding responses, and, based on such responses, automatically modifying timing or operational settings of the stimulation device to improve pacing functionality. Among other things, the approaches described herein reduce unnecessary backup pacing impulses in HIS bundle pacing applications, facilitate fusion in bundle branch block applications, and automatically enable or disable backup pacing in response to achieving QRS complex correction.

The invention relates to a lead device with improved puncturing capability and reliability. The proposed structure, shape and dimensions of a tip of the lead device are configured to enable a controlled and smooth puncturing process through the septum or other tissue at the target area with high reliability and longevity. A fixed helix is provided to facilitate handling and an additional screwing sty let with screwdriver functionality may be provided to improve torque transfer to the tip of the lead device for better control of a puncturing process.

The present invention relates to a screwing lead core for improving torque transmission from a physician's hand to a lead end (e.g., a spiral) of a lead device. A lead end is provided for ease of manipulation, and a screwdriver function of screwing a lead core is provided to improve torque transmission to the lead end of the lead device to better control the piercing process. The screwed lead core may directly engage the end of the wire arrangement, allowing torque to be efficiently transmitted directly to a fixed helix at the end.

The invention relates to a method for determining at least one monitoring parameter for monitoring cardiac stimulation during a magnetic resonance imaging (MRI) scan of a patient, a MRI scanner, and a computer program. According to the method, the patient is positioned in the MRI scanner. The patient's cardiac position relative to the MRI scanner is determined. The at least one monitoring parameter is determined based on a monitoring model as a function of the patient's cardiac position.

The cardiac stimulation device includes a sensing module and a stimulation module. The sensing module is configured to measure at least one cardiac state of a subject. The stimulation module is coupled to the sensing module. The stimulation module includes a stimulation emitting coil, a stimulation control circuit and a stimulation receiver. The stimulation control circuit is coupled to the stimulation emitting coil. The stimulation control circuit is configured to drive the stimulation emitting coil to emit a stimulation electromagnetic signal based on the at least one cardiac state. The stimulation receiver includes a stimulation receiving coil and a stimulation electrode. The stimulation receiving coil is configured to receive the stimulation electromagnetic signal to generate a stimulation voltage provided to the stimulation electrode. The stimulation electrode is arranged at a cardiac stimulation area of the subject. The stimulation voltage is provided to the cardiac stimulation area through the stimulation electrode.

The present invention essentially consists of a coronary diagnostic assembly with a wire guide useful for both measuring pressure within a heart chamber for fractional flow reserve (FFR) and for performing cardiac pacing during pseudo FFR measurements, by means of a pressure sensor integrated within the wire guide.

A method for determining an index for assessing a cardiac function of a subject, includes performing, by elastography, first and second liver stiffness measurements to obtain first and second values of a liver stiffness parameter of the subject, the first and second values being associated with first and second times; determining, by a processing circuit, the index of the cardiac function based on the first and second values, and outputting, via a graphical user interface of a device, the determined index of the cardiac function of the subject. The first value corresponds to a value of the liver stiffness parameter before or immediately after performing a predetermined cardiac stimulation that modifies a cardiovascular system of the subject and the second value corresponds to a value of the liver stiffness parameter obtained after performing the first liver stiffness measurement.

The invention relates to an arrangement (200) comprising a non-transvenous implantable cardioverter-defibrillator device (210) for stimulating a human or animal heart, the non- transvenous implantable cardioverter-defibrillator device (210) comprising a stimulation unit (270) for emitting stimulation pulses (140) externally to the heart; and a programming device (220) operatively coupled to the non-transvenous implantable cardioverter- defibrillator device (210); wherein the arrangement is capable to predict an expected time of occurrence of a future T wave (Bn) by determining the future T wave (Bn) on the basis of a function using first coefficients (ai), second coefficients (ci) and / or third coefficients (di).

Systems, devices, and methods for electroporation ablation therapy are disclosed, with the system including a pulse waveform signal generator for medical ablation therapy, and an endocardial ablation device includes an inflatable member and at least one electrode for focal ablation pulse delivery to tissue. The signal generator may deliver voltage pulses to the ablation device in the form of a pulse waveform. The system may include a cardiac stimulator for generation of pacing signals and for sequenced delivery of pulse waveforms in synchrony with the pacing signal.

An implantable medical device (1) for performing a cardiac stimulation comprises a generator device (12) comprising a processing circuitry (120) for processing electrical signals, an electrode lead (10, 11) connected to the generator device (12) and extending from the generator device (12), the electrode lead (10) comprising a lead body (100) forming a distal end (101) to be arranged on cardiac tissue within a patient's heart (H), and an electrode pole arrangement comprising at least three electrode poles (102, 103, 121). The processing circuitry (120) is configured to generate an electrical stimulation signal (P) and to provide the electrical stimulation signal (P) to said electrode pole arrangement for stimulating cardiac activity. The processing circuitry (120) furthermore is configured to measure at least two electrical response signals (S, SA, SB, SC) indicative of a stimulated cardiac activity in response to said electrical stimulation signal (P) using at least two different pairs of electrode poles out of said at least three electrode poles (102, 103, 121) and to derive information indicative of a stimulation effectiveness of said electrical stimulation signal (P) based on said at least two electrical response signals (S, SA, SB, SC).

Existing clinically adopted epicardial pacing leads mostly rely on surgical suturing or insertion of electrodes to the heart tissue. However, these approaches can cause tissue trauma during application and / or retrieval of the implants, potentially causing detrimental complications such as bleeding, tissue damage, and / or device failure. The present invention reports a bioadhesive epicardial pacing lead for atraumatic epicardial monitoring and stimulation of the heart in vivo to overcome the limitations of existing bioelectronic implants. The bioadhesive pacing lead is composed of an insulation layer, a conductive bioadhesive interface, a built-in reservoir, an electrode lead wire, and a fluidic channel. The bioadhesive pacing lead shows robust mechanical and electrical properties, biocompatibility, continuous epicardial monitoring and pacing capability, and rapid on-demand atraumatic employment and removal.

A system and method for monitoring and treating a patient with heart failure is discussed. The system may receive atrioventricular (AV) conduction characteristics at different heart rates or different patient conditions. Stimulation parameters, including stimulation timing parameters, may be stored in a memory. The system may include stimulation control circuitry configured to use the patient's AV conduction characteristics to determine a parameter update schedule indicating timings at which stimulation parameters are to be updated, and to dynamically update at least a portion of a stored set of stimulation parameters in the determined parameter update schedule. Stimulation parameters may be selected from the set of stimulation parameters for use during cardiac stimulation for a specified heart rate or heart rate range.

The invention relates to a device for assisting in the handling and implantation of at least one electrode support for a cardiac device, in particular a cardiac stimulation device, the at least one electrode support comprising a distal end and a proximal end, the proximal end comprising at least one connector configured to be electrically connected to at least one portion of the distal end, characterized in that the assistance device comprises: - a body, preferably a one-piece body, configured to cover at least a portion of the at least one connector, - at least one receiving portion for a temporary electrical connection means, such as a crocodile clip, the at least one receiving portion being electrically conductive, - at least one connection element connected electrically to the at least one receiving portion, the at least one connection element being in controlled tangential contact with the at least one connector. The invention also relates to the use of this assistance device for transferring electrical signals to or from a cardiac stimulation device electrode, and to a method for assembling this assistance device.

This invention relates to an apparatus and a method for optimizing cardiac stimulation instants of a patient, wherein a signal processing chain and a set of transformations are applied to provide robust, denoised and coherent electrogram (EGM) cycles An orthogonal (uncorrelated) transformation of observed EGMs provides an improved combination of available EGMs in terms of information content, maximizes sensitivity to changes in cardiac therapy configurations and is invariant to anatomy and lead positions of each patient. Furthermore, an original feature extraction is applied after orthogonal transformation of the EGMs and allows for calculation of a set of markers that can be better interpreted and used for optimizing the stimulation instants for a given patient.

An implantable medical device (1) for performing a cardiac stimulation comprises a generator device (12) comprising a processing circuitry (120) for processing electrical signals, an electrode lead (10, 11) connected to the generator device (12) and extending from the generator device (12), the electrode lead (10) comprising a lead body (100) forming a distal end (101) to be arranged on cardiac tissue within a patient's heart (H), and an electrode pole arrangement comprising at least a first electrode pole (102) and a second electrode pole (103, 121). The processing circuitry (120) is configured to generate an electrical stimulation signal and to provide the electrical stimulation signal to said electrode pole arrangement for stimulating cardiac activity. The processing circuitry (120) furthermore is configured to measure, using said electrode pole arrangement, an impedance curve (C1, C2) indicative of a stimulated cardiac activity in response to said electrical stimulation signal and to derive information indicative of a stimulation effectiveness of said electrical stimulation signal based on said impedance curve (C1, C2).

The present application relates to a cardiac therapy device including a subcutaneous defibrillation unit including a first control component configured to detect global cardiac excitation events, generate far-field detected signals indicative of the global excitation events, and deliver defibrillation waves to a patient when the patient experiences a malignant arrhythmia, and a leadless cardiac stimulation unit including a second control component configured to detect local myocardial excitation events at predetermined stimulation sites, generate local detected signals indicative of the local excitation events, and apply stimulating electrical pulses to the predetermined stimulation sites to enhance myocardial contractility, wherein the first control component is wirelessly coupled to the second control component, and the first control component and / or the second control component is configured to determine whether to apply stimulating electrical pulses to the predetermined stimulation sites based on at least the far-field detected signals and the local detected signals.

A method for determining an index for assessing a cardiac function of a subject, includes performing, by elastography, first and second liver stiffness measurements to obtain first and second values of a liver stiffness parameter of the subject, the first and second values being associated with first and second times; determining, by a processing circuit, the index of the cardiac function based on the first and second values, and outputting, via a graphical user interface of a device, the determined index of the cardiac function of the subject. The first value corresponds to a value of the liver stiffness parameter before or immediately after performing a predetermined cardiac stimulation that modifies a cardiovascular system of the subject and the second value corresponds to a value of the liver stiffness parameter obtained after performing the first liver stiffness measurement.

The present invention relates to the field of medical device technology, and is about a multifunctional intracardiac stimulation test device for experimental animals. The device and dual pacing electrodes arranged on the test target form a test system, realize the intracardiac induction and defibrillation function, and realize the test of transcardiac current during the external defibrillation process. The device comprises: a power supply module, an intracardiac induction / defibrillation module, a transcardiac voltage measurement module and an interface module; the power supply module is used to supply power to other modules in the device; the intracardiac induction / defibrillation module is used to output an induction waveform or a defibrillation waveform to the test target; the transcardiac voltage measurement module obtains the transcardiac current of the test target by measuring the voltage between the external dual pacing electrodes placed outside the target ventricle.

A method for ascertaining at least one monitoring parameter for monitoring cardiac stimulation during a magnetic resonance measurement of a patient, a magnetic resonance apparatus, and a computer program product are provided. According to the method, the patient is positioned in the magnetic resonance apparatus. The cardiac position of the patient relative to the magnetic resonance apparatus is ascertained. The at least one monitoring parameter is ascertained based on a monitoring model as a function of the cardiac position of the patient.

Esophageal intubation assemblies, esophageal cardiac stimulation and gastric decompression assemblies, and methods for using and making the same are provided.

The endovascular catheter monitors respiratory and hemodynamic indices and simultaneously delivers cardiac stimulation, enabling cardiac rhythm regulation with respect to pleural pressure for adaptive treatment of heart failure, low cardiac output, or pulmonary congestion. The catheter is capable of measuring instantaneous pleural pressure based on measurement of intravascular volume and pressure of a large elastic blood vessel within the thoracic cavity.