7 results about "Depolarization" patented technology

A dual-chamber leadless pacemaker (LP) system includes a first leadless pacemaker (LP1) and a second leadless pacemaker (LP2), wherein LP1 is configured to be implanted in or on a first heart chamber and deliver pacing pulses to the first heart chamber, and LP2 is configured to be implanted in or on a second heart chamber and deliver pacing pulses to the second heart chamber. Information is obtained regarding the amplitude of the pacing pulses delivered by LP2 to the second heart chamber and / or the sensitivity of a sensing circuit of LP1, which is configured to be used by LP1 to detect the inherent depolarization of the first heart chamber. A crosstalk protection duration is determined based on at least some of this information, such that it is performed for an appropriate duration when crosstalk protection is executed.

Provided herein are depolarizing ion channel therapeutics and methods of using the same for boosting retinal neuronal function.

A clinical evaluation system and method are disclosed that facilitate the use of one or more morphologic atrial depolarization waveform-based features or parameters determined from biophysical signals such as cardiac or biopotential signals that are acquired, in preferred embodiments, non-invasively from surface sensors placed on a patient while the patient is at rest. Morphologic atrial depolarization waveform-based features or parameters can be used in a model or classifier to estimate metrics associated with the physiological state of a patient, including the presence or non-presence of a disease, medical condition, or an indication of either. The estimated metric may be used to assist a physician or other healthcare provider in diagnosing the presence or non-presence and / or severity and / or localization of diseases or conditions or in the treatment of said diseases or conditions.

The application is suitable for the field of biofeedback technology, and provides a non-invasive feedback method, device, equipment and program product for pelvic floor muscle training. The method comprises the following steps: in the process of pelvic floor muscle training of a living body, an active electrode arranged on the pelvic floor muscle of the living body is used to acquire a first electromyographic signal generated by the depolarization of the pelvic floor muscle fiber when the pelvic floor muscle contracts; and whether the pelvic floor muscle training performed by the living body meets a preset requirement is determined according to the first electromyographic signal. In the method, the electromyographic signal used to determine whether the pelvic floor muscle training performed by the living body meets the preset requirement is acquired by the active electrode arranged on the pelvic floor muscle of the living body. Since the active electrode can be directly attached to the skin, the effect of the pelvic floor muscle training can be determined without using a vaginal probe, and therefore, the effect of the pelvic floor muscle training performed by the living body can be determined non-invasively, and the safety and comfort of the pelvic floor muscle training are improved.

A therapy system includes an implantable medical device including one or more implantable electrodes (40, 42, 48, 50, 94), and a computing apparatus (24) including processing circuitry and operably coupled to the one or more implantable electrodes (40, 42, 48, 50, 94). The one or more implantable electrodes (40, 42, 48, 50, 94) include a left bundle branch (LBB) electrode positionable adjacent a portion of a patient's LBB, and a right bundle branch (RBB) electrode positionable adjacent a portion of the patient's RBB. The computing apparatus (24) is configured to monitor electrical activity using the LBB and RBB electrodes, detect electrical activity based on the monitored electrical activity indicative of left ventricle (LV) depolarization and indicative of right ventricle (RV) depolarization, determine a temporal difference based on the detected electrical activity indicative of LV depolarization and the detected electrical activity indicative of RV depolarization, and determine whether there is a cardiac physiological condition based on the determined difference.