23 results about "Stimulus pulse" patented technology

A method of conducting operations for an IPG adapted to provide electrical pulses to tissue of a patient for medical therapy is provided. The IPG provides the medical therapy according to pulse parameter data executed according to an execution path. The method can include identifying a root node repeated within the execution path of a first set of the pulse parameter data, identifying a stimulation pulse pattern repeated in the first set between occurrences of the root node, replacing the repeated pattern with (a) a single instance and a recurrence count or (b) a pointer to a reference pattern to generate a second set of the pulse parameter data, and communicating the second set between the external controller and the IPG and / or storing the second set within a memory of the IPG.

The application discloses a closed-loop trigger timing compensation method and system based on full-link delay measurement. The method comprises the following steps: obtaining a collected patient electroencephalogram signal and performing band-pass filtering to obtain a channel signal; calculating an individual target frequency and an individual target frequency band based on the channel signal; determining an optimal autoregressive model order based on the individual target frequency band and the channel signal; measuring the time from receiving the patient electroencephalogram signal to the magnetic stimulator emitting a stimulation pulse to determine a delay compensation point number, and processing the patient electroencephalogram signal to obtain a target oscillation signal; fitting the target oscillation signal using the optimal autoregressive model order, combining the delay compensation point number, and outputting a predicted signal sequence; and judging whether to control the magnetic stimulator to trigger stimulation based on the predicted signal sequence. The application realizes precise synchronization of TMS pulses and electroencephalogram alpha negative peaks, and provides a synchronized and visualized therapeutic effect monitoring means for clinical use.

This invention describes techniques for a medical device that delivers electrical stimulation using a current or voltage regulator with an adjustable principal amplitude. An exemplary method includes: receiving user input indicating a desired current amplitude via a programmer for an electrical stimulator; and selecting a first fractional adjustment or a second fractional adjustment as a target adjustment for achieving the desired current amplitude. A neural modulation system includes: a first electrode; a second electrode; a stimulation generator configured to deliver a first stimulation pulse to the first electrode and a second stimulation pulse to the second electrode, wherein a first current amplitude of the first stimulation pulse is a first fraction of the principal amplitude and a second current amplitude of the second stimulation pulse is a second fraction of the principal amplitude; and a processor configured to: generate initial instructions for the stimulation generator to perform: (i) deliver the first analog pulse based on the first fraction of the principal amplitude, and (ii) deliver the second stimulation pulse based on the second fraction of the principal amplitude, receiving user input including the desired current amplitude. The processor determines, based on the desired current amplitude, the adjustment of the first current amplitude of the first stimulation pulse to be required, and determines a target adjustment based at least in part on a comparison of the desired current amplitude with the main amplitude, wherein the processor is further configured to: (A) determine an adjustment to at least the first fraction as the target adjustment, or (B) determine the following as the target adjustment: (i) an adjustment to the main amplitude, and (ii) an adjustment to at least the second fraction relative to the main amplitude adjustment, and, based at least in part on the target adjustment, generate adjustment instructions for the stimulation generator to deliver the first stimulation pulse with the desired current amplitude and the second stimulation pulse with approximately the same second current amplitude.

The present application relates to an implantable electrical stimulation system and a control method. The system comprises an electrode assembly, the electrode assembly comprising a stress release section for buffering stress transmitted from the tail end of the electrode assembly and at least one contact; the stimulation section and the stress release section are connected according to a bending angle. The system further comprises a processing unit configured to, based on the measurement of the activity in the brain region of the patient, control the pulse generator to generate stimulation pulses in a first time sequence; in a second time sequence, update the electrical stimulation scheme to a second stimulation parameter set based on the degree of coincidence between the feedback information of the activity in the brain region of the patient and the expected activity information; in a third time sequence, control the at least one contact remaining to the patient to electrically stimulate the patient to regulate the state of the patient to a normal state in the third stimulation parameter set. The present application combines the electrode structure conforming to the physiological characteristics and the adaptive pulse control.

Systems, devices, and techniques for analyzing evoked compound action potentials (ECAP)signals to evaluate and select an electrode combination. A method includes controlling, by processing circuitry, deliver of a plurality of stimulation pulses via at least one stimulation electrode combination, receiving, by the processing circuitry, evoked compound action potential (ECAP) signal information representing different ECAP signals evoked from respective stimulation pulses of the plurality of stimulation pulses and obtained from respective different sensing electrode combinations, selecting by the processing circuitry and based on the ECAP signal information, one electrode combination from the different sensing electrode combinations.

The present application relates to a kind of based on motor imagination trigger's electric stimulation synchronous closed loop multimodal neuroregulation system, belong to medical rehabilitation engineering and neural engineering technical field.The system includes: electroencephalogram signal acquisition and processing module, for real-time acquisition user sensory motor cortex electroencephalogram signal, and extract the event-related desynchronization features of motor imagination task in the electroencephalogram signal by time-frequency analysis model;Motor intention recognition and trigger module generates synchronous trigger signal;Functional electric stimulation module, through multi-channel electrode device drive surface electrode output electric stimulation pulse to target area, drive target action;Transcutaneous auricular vagus nerve electric stimulation module, output and motor intention duration synchronous stimulation pulse;Central control and synchronization module, for coordination control timing.Formed " intention recognition-synchronous control-assisted movement" complete closed loop, provides a kind of efficient, accurate, individualized neural engineering solution.

This invention discloses a muscle stimulation modulation system and method based on real-time dynamic optimization, comprising: a real-time signal acquisition module for continuously acquiring multimodal physiological signals of the target limb, including at least electromyography (EMG) signals, joint kinematic angle signals, and neural electrical signals; a state assessment and prediction module for calculating real-time human state indicators based on the multimodal physiological signals, fusing historical state data, and generating future state trend prediction information through a time series prediction model; and a dynamic parameter optimization module for solving the optimal combination of stimulation parameters for the neuromuscular stimulator in real-time using an embedded optimization algorithm, based on the real-time human state indicators and state trend prediction information, with minimizing the objective function as the core. The stimulation parameter combination includes stimulation pulse intensity, frequency sequence, and waveform duty cycle. This invention enables better muscle stimulation modulation.

This invention relates to the fields of digital therapy, intelligent medical devices, and applied artificial intelligence technologies, and more specifically to a closed-loop pain management method and system integrating diagnostic assistance and interference-resistant sensing. It includes: a wearable device comprising: a neuromodulation signal generator configured to generate neuromodulation stimulation pulses; a biosensor array physically integrated with the neuromodulation signal generator configured to sense physiological data indicating the user's autonomic nervous system activity; a controller configured to execute a time-division multiplexing protocol; a processor; and a non-transitory computer-readable storage medium associated with the processor for generating a diagnostic support report. This invention enables simultaneous effective neural stimulation and high-fidelity ANS signal acquisition on a single wearable device.

The application provides an implantable closed-loop neural stimulation system and a power consumption management method thereof. The power consumption management method comprises: determining first values of a plurality of characteristic parameters based on real-time collected electroencephalogram signals; when it is determined that the first values of the plurality of characteristic parameters meet a preset trigger condition of a neural abnormal event, switching a current working mode to a first working mode and applying an intervention stimulation pulse to the electrode; within a first time window after applying the intervention stimulation pulse, obtaining second values of the plurality of characteristic parameters; when it is determined that the first values and the second values of the plurality of characteristic parameters meet a preset condition, switching the first working mode to a second working mode, or adaptively adjusting parameters of the intervention stimulation pulse, wherein the power consumption of the first working mode is higher than that of the current working mode, and the power consumption of the second working mode is lower than that of the current working mode.

A brain-computer interface (BCI) includes a multichannel stimulator and a decoder. The multichannel stimulator is operatively connected to deliver stimulation pulses to a functional electrical stimulation (FES) device to control delivery of FES to an anatomical region. The decoder is operatively connected to receive at least one neural signal from at least one electrode operatively connected with a motor cortex. The decoder controls the multichannel stimulator based on the received at least one neural signal. The decoder comprises a computer programmed to process the received at least one neural signal using a deep neural network. The decoder may include a long short-term memory (LSTM) layer outputting to a convolutional layer in turn outputting to at least one fully connected neural network layer. The decoder may be updated by unsupervised updating. The decoder may be extended to include additional functions by transfer learning.

This invention discloses a spinal cord stimulation pulse generator and a spinal cord stimulation system. The spinal cord stimulation pulse generator receives user information sent by a programmable device to obtain the target user's ECAP guidance range and target ECAP amplitude E. T The system acquires ECAP signals via stimulation electrodes. Based on whether the ECAP amplitude of the current cycle or the weighted ECAP amplitude of multiple adjacent cycles exceeds the range, a control algorithm is executed to determine the stimulation parameters for the next cycle, ultimately stabilizing the ECAP amplitude at the target ECAP amplitude within the ECAP guidance range. T This allows for dynamic and precise stimulation adjustment, enhancing the stability of spinal cord electrical stimulation.

This invention discloses an intelligent visual prosthesis system and encoding method. The system includes an external sensing processing unit and an internal implanted stimulation unit. The external sensing processing unit includes at least an environment sensing unit and a first data processing unit, and the internal implanted stimulation unit includes at least a stimulation signal generation unit and an electrode array. The environment sensing unit is used to acquire a target image. The first data processing unit is used to match the current scene to a preset lighting scene mode according to the image features or ambient illuminance of the target image, independently configure anchor points for the corresponding image grayscale value boundaries for the matched lighting scene mode, and generate a grayscale-charge density mapping relationship corresponding to the lighting scene mode. Then, the grayscale value of each pixel of the target image is mapped to the corresponding target charge density, and a stimulation command is generated and output to the stimulation signal generation unit. The stimulation signal generation unit is used to generate an electrical stimulation pulse sequence according to the stimulation command and a preset reference pulse width and output it to the electrode array.

One example of a device includes a clock, a sensing circuit, and a stimulation circuit. The clock is configured to generate a clock signal. The sensing circuit is configured to periodically sense a signal based on the clock signal. The stimulation circuit is configured to output a stimulation pulse train relative to the periodic sensing of the signal based on the clock signal.

A TENS device (100) comprises connection port(s) (110, 112, 115) configured to be electrically connected to cymba concha and cavum concha electrodes (220, 230) of a taVNS device (200) The TENS device (100) comprises a pulse generator (140) connected to the connection port(s) (110, 112, 115) and arranged to generate adjustable electrical stimulations pulses to be applied over the cymba concha and cavum concha electrodes (220, 230). A controller (150) of the TENS device (100) is configured to adjust, in response to activation of a user input (120), a stimulation parameter of the adjustable electrical stimulation pulses generated by the pulse generator (140) during a treatment session, store, in a memory (160), treatment information comprising settings of the stimulation parameter, retrieve, in response to activation of the user input (120), the treatment information from the memory (160) and control the pulse generator (140) to generate, during a subsequent treatment session, adjustable electrical stimulation pulses according to the settings of the stimulation parameter comprised in the retrieved treatment information.

This application discloses a cochlear implantation system with improved time feature selection, comprising: a microphone unit; an electrode array; a processor unit including: a filter bank; a first time feature extractor configured to determine an initial set of time features of a bandpass audio signal; a second time feature extractor configured to window-filter the bandpass audio signal and determine a secondary set of time features of the window-filtered bandpass audio signal; a stimulation generator configured to determine a final set of time features based on the initial set of time features and the secondary set of time features, and to determine a similarity measure value between the initial set of time features and the secondary set of time features for the final set of time features; the processor unit configured to determine, based on the similarity measure value, whether the final set of time features will be encoded into a stimulation pulse; the encoded stimulation pulse is transmitted to an electrode configured to apply electrical stimulation to a group of auditory nerve fibers based on the encoded stimulation pulse.

The invention relates to an electronic implant (100a,b) for implantation into the body of a living being and for monitoring and / or stimulating a bodily function, in particular a pacemaker for monitoring and / or stimulating the human heart, wherein the implant comprises: a housing (1a) which accommodates (i) electronics connected to an electrode (3a) configured to monitor bodily function via the electrode (3a) and / or to deliver a stimulation pulse to a body section (H), and (ii) a preferably rechargeable energy storage device (2a) for the long-term supply of electrical energy to the electronics; and an anchoring section (VA) for anchoring the electronic implant (100a,b) to the body section (H), wherein the anchoring section (VA) comprises an anchor (VA1) which is screwed into the body section (H) by a rotational movement, and a rotation lock which preferably extends in the direction of a rotational axis (RA) corresponding to the rotational movement and prevents a rotational movement of the anchor (VA1) in the opposite direction to the rotational movement after the anchor (VA1) has been screwed in.

Devices, systems, or methods include generating, by stimulation generation circuitry, a first train of electrical stimulation pulses at a first frequency to a first target tissue; and generating, by the stimulation generation circuitry, a second train of electrical stimulation pulses at a second frequency to a second target tissue different from the first target tissue, wherein at least some electrical stimulation pulses of the first train of electrical stimulation pulses are interleaved with at least some electrical stimulation pulses of the second tram of electrical stimulation pulses. At least the first target tissue is associated with a spinal cord of a patient, and the second target tissue is associated with at least one of a peripheral nerve or a nerve root of the patient.

This application relates to the field of detection and treatment technology for neurological and mental illnesses. This application discloses a transcranial magnetic stimulation (TMS) medical system guided by multimodal physiological signals. It includes: a host computer software module, a navigation robot, a TMS device, a stimulation coil, a stimulation pulse conversion module, a multimodal physiological signal acquisition terminal, and a physiological probe connected to the multimodal physiological signal acquisition terminal. The host computer software module includes: an examination item unit, a data processing unit, a protocol management unit, a synchronization control unit, and an evaluation system. The technical solution of this application effectively solves the technical problems of poor synchronization between traditional TMS devices and the body's physiological signal detection, inaccurate target marking, fragmented functions, and a single evaluation dimension through hardware and software linkage control, synchronous acquisition of multimodal physiological signals and stimulation pulse signals, automatic target marking, and highly integrated software management. It also provides convenience for efficacy evaluation.

Methods and systems for spinal cord stimulation (SCS) are disclosed. The methods and systems involve using electrode leads implanted within the patient's spinal column to record neural responses evoked by the stimulation. The disclosed neural responses are different in several respects from electrical responses that have previously been measured in the context of SCS, such as stimulation artifacts and evoked compound action potentials (ECAPs). The disclosed neural responses typically occur later in time following the evoking stimulation pulse. Another distinguishing feature is that disclosed neural responses are generally most prominently observed with consistent, relatively unchanging amplitudes when the evoking stimulation frequency is ultra-low, for example, about 10 Hz or less. The disclosed methods and systems may use these neural responses as indications of pain, therapy, and / or another clinically relevant dimension, to direct / confirm stimulation placement, and for feedback control of stimulation parameters.

Devices, systems, and techniques for controlling electrical stimulation therapy are described. In one example, a system is configured to deliver, via a first electrode combination, a first stimulation pulse to a portion of a spinal cord of a patient located caudally of a spinal cord injury location of the spinal cord of the patient; sense, via a second electrode combination, an evoked compound action potential (ECAP) signal elicited by the first stimulation pulse; identify, by processing circuitry, a characteristic of the ECAP signal; determine, by the processing circuitry and based on the characteristic of the ECAP signal, a therapy parameter value that at least partially defines a second stimulation pulse; and deliver the second stimulation pulse according to the determined therapy parameter value.

This invention discloses a method for monitoring catering fume emissions based on edge computing, comprising the following steps: collecting catering kitchen fume sensor data, operational behavior data, and environmental parameter data; generating fume emission pulse sequences and operational stimulus pulse sequences; establishing propagation correlations to form a fume emission synaptic network; generating emission behavior neural coding sequences based on the relationship between the operational stimulus pulse sequences and the fume emission pulse sequences; marking synaptic connections as synaptic locked states when stability criteria are met; performing propagation calculations to obtain counterfactual pulse propagation paths and identifying key pollution triggering behaviors; updating synaptic connection weights to obtain a dynamic synaptic structure; and combining key pollution triggering behaviors with the dynamic synaptic structure to generate abnormal fume emission warning information. This invention utilizes counterfactual propagation and dynamic synaptic control methods to achieve causal identification of fume emissions, possessing advantages of high accuracy and robustness.

An implantable stimulation system having a stimulation unit coupled to a programmable controller, a stimulation circuit and an array of electrodes disposed on a pair of flexible paddles is provided for selectively stimulating at least one pelvic (e.g., cavernous) nerve. The programmable controller is pre-programmed to run an excitation electrode routine that selectively scans the electrode arrays with a series of directional current flows to optimize electrode selection for use in stimulating a nerve. The implantable stimulation system may be programmed to run a first stimulation pulse sequence corresponding to a first mode for invoking a rapid erectile response, a second nerve rehabilitation stimulation mode for rehabilitating neural transmission in a cavernous nerve, a third penile rehabilitation mode for reducing penile fibrosis, and / or a fourth bladder nerve rehabilitation mode for rehabilitating neural transmission in nerves that control the lower urinary tract. Methods of operating the system also are provided.