90 results about "Diagnostic evaluation" patented technology

The present invention relates to methods and compositions for the treatment and diagnosis of cardiovascular disease, including, but not limited to, atherosclerosis, ischemia/reperfusion, hypertension, restenosis, and arterial inflammation. Specifically, the present invention identifies and describes genes which are differentially expressed in cardiovascular disease states, relative to their expression in normal, or non-cardiovascular disease states, and/or in response to manipulations relevant to cardiovascular disease. Further, the present invention identifies and describes genes via the ability of their gene products to interact with gene products involved in cardiovascular disease. Still further, the present invention provides methods for the identification and therapeutic use of compounds as treatments of cardiovascular disease. Moreover, the present invention provides methods for the diagnostic monitoring of patients undergoing clinical evaluation for the treatment of cardiovascular disease, and for monitoring the efficacy of compounds in clinical trials. Additionally, the present invention describes methods for the diagnostic evaluation and prognosis of various cardiovascular diseases, and for the identification of subjects exhibiting a predisposition to such conditions.

The present invention relates to methods for the diagnosis, evaluation, and treatment of mood disorders, particularly bipolar disorder. In particular, patient test samples are analyzed for the presence and amount of members of a panel of biallelic markers comprising one or more specific markers for bipolar treatment and one or more non-specific markers for bipolar treatment. A variety of markers are disclosed for assembling a panel of markers for such diagnosis and evaluation. Algorithms for determining proper treatment are disclosed. A diagnostic kit for a panel of said markers is disclosed. In various aspects, the invention provides methods for the early detection and differentiation of mood disorders or bipolar treatment. Methods for screening therapeutic compounds for mood disorders are disclosed. The invention (1) gives methods providing rapid, sensitive and specific assays that can greatly increase the number of patients that can receive beneficial treatment and therapy, thereby reducing the costs associated with incorrect diagnosis, and (2) provides methods for improved therapies.

The inventive subject matter as a whole is an improved transceiver apparatus and system for diagnostic evaluations of living subject, human or animal; and is particularly effective as a clinical tool for the spectroscopic scanning or magnetic resonance imaging of humans suspected of being afflicted with a particular disease, disorder, or pathology. The improved transceiver apparatus is used as an essential component in a computer controlled system suitable for magnetic resonance imaging (“MRI”), or nuclear magnetic resonance spectroscopy (“MRS”), and/or nuclear magnetic resonance spectroscopic imaging (“MRSI”); and the present improvement of these electromagnetic signaling systems will provide far more accurate and precise visual images and accumulated data for the clinician or surgeon, as well as serve as a basis upon which to make a diagnosis and decide upon a mode of therapeutic treatment for that individual.

The present invention relates to methods and compositions for the treatment and diagnosis of immune disorders, especially T helper lymphocyte-related disorders. For example, genes which are differentially expressed within and among T helper (TH) cells and TH cell subpopulations, which include, but are not limited to TH0, TH1 and TH2 cell subpopulations are identified. Genes are also identified via the ability of their gene products to interact with gene products involved in the differentiation, maintenance and effector function of such TH cells and TH cell subpopulations. The genes identified can be used diagnostically or as targets for therapeutic intervention. In this regard, the present invention provides methods for the identification and therapeutic use of compounds as treatments of immune disorders, especially TH cell subpopulation-related disorders. Additionally, methods are provided for the diagnostic evaluation and prognosis of TH cell subpopulation-related disorders, for the identification of subjects exhibiting a predisposition to such conditions, for monitoring patients undergoing clinical evaluation for the treatment of such disorders, and for monitoring the efficacy of compounds used in clinical trials.

The present invention relates to methods and compositions for the treatment and diagnosis of immune disorders, especially T helper lymphocyte-related disorders. For example, genes which are differentially expressed within and among T helper (TH) cells and TH cell subpopulations, which include, but are not limited to TH0, TH1 and TH2 cell subpopulations are identified. Genes are also identified via the ability of their gene products to interact with gene products involved in the differentiation, maintenance and effector function of such TH cells and TH cell subpopulations. The genes identified can be used diagnostically or as targets for therapeutic intervention. In this regard, the present invention provides methods for the identification and therapeutic use of compounds as treatments of immune disorders, especially TH cell subpopulation-related disorders. Additionally, methods are provided for the diagnostic evaluation and prognosis of TH cell subpopulation-related disorders, for the identification of subjects exhibiting a predisposition to such conditions, for monitoring patients undergoing clinical evaluation for the treatment of such disorders, and for monitoring the efficacy of compounds used in clinical trials.

A device for obtaining dental measurements to determine a patient's occlusal vertical dimension and centric relation position where these dental measurements are used to make dentures for the patient; and for obtaining dental measurements for balancing a patient's dentures and methods for making these dental measurements with the device. The device comprises a contact plate, a post, a ball nut, and a striking plate, where the combination of the contact plate being attached to the central lingual surface of the lower base plate, the ball nut being swivelably attached in a tapered opening in the contact plate, the post being adjustably secured to the ball nut; and the striking plate being attached to the central lingual surface of the upper base plate, are received in the mouth of the patient such that they cooperate with each other to obtain dental measurements including, but not limited to, occlusal vertical dimension, centric relation position, or measurements for balancing a patient's dentures.

A patient immobilization device for immobilizing a patient and performing a diagnostic evaluation of such patient is comprised of a backboard, a structure configured to support the head of a patient on the backboard, and a pupil-sizing indicator positioned on a surface of the support structure to be visually accessible to a person that is visually evaluating the head and face of an immobilized patient on the backboard.

The present invention relates to methods and compositions for the treatment of body weight disorders, including, but not limited to, obesity. Specifically, the present invention identifies and describes genes which are differentially expressed in body weight disorder states, relative to their expression in normal, or non-body weight disorder states, and/or in response to manipulations relevant to appetite and/or weight regulation. Further, the present invention identifies and describes genes via the ability of their gene products to interact with gene products involved in body weight disorders and/or appetite and/or body weight regulation. Still further, the present invention provides methods for the identification and therapeutic use of compounds as treatments of body weight disorders. Additionally, the present invention describes methods for the diagnostic evaluation and prognosis of various body weight disorders, and for the identification of subjects exhibiting a predisposition to such conditions.

An adaptive optics microperimetry, infrared beacon emits infrared light to the pupil of the subject, the Hartmann wavefront sensor measures the wavefront aberration of the human eye carried by the reflected light of the fundus, and the computer calculates the control voltage based on the measured aberration , driving the wavefront corrector to correct the aberration of the human eye. After the aberration correction is completed, the fixed optotype for fixing the line of sight of the examinee and the optical stimulation optotype for providing optical stimulation to the fundus of the examinee are displayed at a plurality of predetermined positions on the stimulus optotype display device. The pupil camera uses the infrared light emitted by the infrared light source in front of the eye to capture the subject's human eye pupil image and calculate the pupil diameter. The computer controls the change of the optical stimulus visual target according to the change of the subject's pupil diameter, and measures the subject's field of vision. The invention has high reliability, reduces the stimulus redundancy caused by the aberration of the human eye in the visual field test, is beneficial to discover early micro-perspective defects, and provides a powerful tool for the evaluation of the micro-perspective defects of the human eye and the diagnosis of related diseases.

A system and method for remote servicing of an in-field product at a customer site. The remote servicing system includes a portable service interface, typically a laptop computer, which is utilized to connect a remote servicing on-line center with the in-field produce, such as a medical image scanner. The portable service interface includes software not resident with the in-field product to permit such servicing functions as diagnostic evaluations of the in-field product, as well as downloading configuration files, original source files, protocols and other software from the on-line center through the portable service interface at the customer site. The field engineer or other operator is able to provide service functions to in-field products that are not networked or are not readily networked with the on-line center and that do not have the on-line center connecting software resident on the portable service interface.

The invention discloses a diagnostic evaluation method considering disturbing influence for a satellite sensor fault. The diagnostic evaluation method comprises the following steps: aiming at a satellite sensor system influenced by interference factors such as noise and modeling nondeterminacy, respectively taking vector distance similarity and vector direction similarity as evaluation indexes to realize the detection and isolability quantitative evaluation of the sensor fault through deploying conditions of mathematical description, system model and a satellite sensor of a fault mode. The diagnostic evaluation method provided by the invention can bring the fault diagnosis of the satellite sensor forward to a design stage on the condition of not depending on any fault diagnosis algorithm, and guide the optimal configuration of the satellite sensor.

The present application discloses solid compositions for the oral administration of dyes, and diagnostic use thereof. Preferably, such diagnostic use is aimed at the diagnostic evaluation of the gastrointestinal tract.

The present invention relates to methods and compositions for the treatment and diagnosis of immune disorders, especially T helper lymphocyte-related disorders. For example, genes which are differentially expressed within and among T helper (TH) cells and TH cell subpopulations, which include, but are not limited to TH0, TH1 and TH2 cell subpopulations are identified. Genes are also identified via the ability of their gene products to interact with gene products involved in the differentiation, maintenance and effector function of such TH cells and TH cell subpopulations. The genes identified can be used diagnostically or as targets for therapeutic intervention. In this regard, the present invention provides methods for the identification and therapeutic use of compounds as treatments of immune disorders, especially TH cell subpopulation-related disorders. Additionally, methods are provided for the diagnostic evaluation and prognosis of TH cell subpopulation-related disorders, for the identification of subjects exhibiting a predisposition to such conditions, for monitoring patients undergoing clinical evaluation for the treatment of such disorders, and for monitoring the efficacy of compounds used in clinical trials.

The invention is an evaporation waveguide monitoring, diagnosing and evaluating method and device, characterized in that the device is composed of temperature-humidity sensor, electromagnetic wind direction-speed sensor, GPS receiver, air pressure sensor, compass converter, data collector, LCD, communication interface, Flash memory, AC power supply, and multi-channel serial communication and calculation display unit and the method includes the steps: real-time measuring hydro-meteorological parameters and diagnosing the evaporation waveguide height and the vertical distribution of atmosphere correction refraction indexes; calculating the cut-off frequency and cut-off wavelength of a radar, and integrated with the input radar parameters and target parameters, calculating the transmission losses and maximum detection distance of the radar electromagnetic wave to draw a distribution diagram of detection probability of the radar; evaluating if the distribution diagram has over-the-horizon ability. Its advantages: simplifying the measuring method; continuously and real-timely measuring the hydro-meteorological parameters; and the accuracies of evaporation waveguide engine value diagnosis and radar detection evaluation reach above 95%.