122 results about "Diagnostic test" patented technology

A diagnostic test device to perform a test on a biological or environmental sample is provided. In one aspect, the diagnostic test device includes a chamber configured to receive a fluid from a sample preparation reservoir at a first section of the chamber, and a plurality of spaced apart valleys along an inner surface of the at least one chamber. Each of the plurality of spaced apart valleys include a curved cross-section and is configured to promote flow of the fluid toward a second section of the at least one chamber.

A diagnostic test device to perform a test on a biological or environmental sample is provided. In one aspect, the diagnostic test device includes a chamber configured to receive a fluid from a sample preparation reservoir at a first section of the chamber, and one or more capillary grooves along an inner surface of the chamber. The capillary grooves are configured to promote flow of the fluid toward a second section of the chamber. Embodiments of the diagnostic test reservoir can increase an amount of sample available to an assay reaction, which in one example embodiment occurs within a volume of fluid in the second section of the chamber.

The utility model relates to the field of medical diagnosis, and discloses a medical antibody diagnosis detection kit which comprises a kit body, a protective structure is sleeved on the outer side wall of the kit body, a plurality of shock absorbers are arranged on the lower end face of the kit body in a rectangular manner, a placing platform is arranged in the center of the lower inner wall of the kit body, a cavity is arranged in the center of the interior of the placing platform, and the shock absorbers are arranged in the cavity. A movable extending structure is arranged in the cavity, and a clamping structure is arranged on the upper end face of the containing platform and the upper end face of the movable extending structure. According to the utility model, the combination of the buffer layer, the elastic layer and the plurality of springs is adopted, so that external impact and vibration are effectively absorbed, the influence of external impact on internal reagents is effectively reduced, the internal reagents are protected from being damaged, the service life of the kit is prolonged, and the position adjustment of the extension block is realized through the sliding of the sliding block plate in the sliding chute; the space utilization rate and the equipment compactness are improved, and the flexibility and the applicability of the medical antibody diagnosis and detection kit are enhanced.

Method, system, apparatus, and computer-readable media for reporting an automated medical opinion, including receiving, via a user interface, patient medical history, diagnostic tests, and current symptoms for a user; identifying, as automated output from a trained model, a diagnostic assessment including one or more of a medical diagnosis, a recommended medical treatment, or an recommended diagnostic medical test based on the patient medical history, diagnostic tests, and current symptoms received via the user interface; sending a report to the user based on the diagnostic assessment; receiving, via a feedback loop, feedback for the diagnostic assessment reported to the user; and updating the trained model based on the feedback.

Disclosed herein are systems, methods, and devices for an image-based, computer vision approach for anthropometric measurement of a user using an automatically generated three-dimensional model of the user. Also disclosed herein are systems, methods, and devices associated with a telehealth proctoring platform that can be used to remotely proctor, monitor, and manage patients over the course of a medical treatment plan. The telehealth proctoring platform may be used to collect and retrieve various kinds of data associated with a patient, such as at-home diagnostic test data, the anthropometric measurements of the patient, or the generated three-dimensional models in order to remotely monitor and track changes to the body of a patient over time and make dynamic adjustments to the patient's medical treatment plan.

A biodegradable and mouldable cassette for lateral flow assay device, and a lateral flow assay device comprising said cassette, and a kit comprising such a lateral flow assay device, for in vitro diagnostics of a biological sample comprising a diagnostic test strip inserted into the cassette. The cassette comprises a first cassette part and a second cassette part coupled to each other and defining a test chamber there between containing the diagnostic test strip. The cassette is made of a biodegradable material and at least one of the first cassette part and second cassette part is made of injection mouldable material, in particular gelatin or a gelatin composition.

The present invention provides a nanofiber membrane having dual scale porosity, which is manufactured by a phase separation electrospinning method. The nanofiber membrane is composed of interfibrous pores and surface pores which are interconnected, thereby enhancing air permeability, diffusion rate and filtration performance. The methods employ solvents having different evaporation rates to induce phase separation during electrospinning, resulting in high porosity structures. The nanofiber membranes are suitable for use in air filtration, medical dressings, drug delivery systems, and diagnostic test paper, thereby improving performance characteristics, such as reducing pressure drop, enhancing diffusion, and increasing diagnostic sensitivity. The method enables cost-effective and scalable production while ensuring consistency of fiber morphology.

The present invention relates to a non-invasive test for the detection of deep endometriosis. Particularly, although not exclusively, aspects of the present invention relate to one or more glycolysis-associated biomarkers (e.g., phosphoglycerate mutase 1 (PGAM1), Enolase-1 (ENO1), phosphofructokinase-1 (PFKP) and / or Hexokinase) and / or cytokines associated with aerobic glycolysis (e.g., IL-6 and / or TGF-β) which can be used to determine the likelihood of a subject having deep endometriosis based on a sample obtained from the subject.

The invention discloses an automatic diagnosis and test system based on a vehicle body domain controller, and relates to the technical field of vehicle body domain controller diagnosis and test, and the system is composed of a vehicle body domain controller, a controlled equipment monitoring module and a dynamic diagnosis module. The vehicle body domain controller sends a diagnosis command with a timestamp to the controlled equipment through the multiplexing communication interface; the controlled equipment monitoring module is responsible for monitoring response of controlled equipment and generating a state feedback signal containing performance indexes, and the performance indexes cover response delay, execution precision and an energy consumption coefficient; and the dynamic diagnosis module combines the performance indexes with time, constructs a space-time fusion coordinate system, records three-dimensional health track points, and constructs a diagnosis boundary curved surface. By calculating the mahalanobis distance, the system can judge the health state of the controlled equipment and write a result into a block chain evidence storage block for an operator to look up; the system integrates a plurality of technical means, and realizes comprehensive, accurate and real-time diagnosis of controlled equipment.

The combined use of a first antibody molecule that specifically binds to Fc [gamma] RIIb through its Fab region and binds to Fc [gamma] receptor through its Fc region and a second antibody molecule that specifically binds to PD-1 and binds to at least one Fc [gamma] receptor through its Fc region in the treatment of cancer in a patient having tumor-infiltrating T lymphocytes having medium or high PD-1 expression is described, as well as pharmaceutical compositions and kits comprising these two antibody molecules, as well as methods of using these two antibodies to treat cancer. A diagnostic test for identifying patients who benefit from the treatment described herein is also described.

The invention provides a response method and device for a diagnostic service program under ECU simulation, and relates to the technical field of ECU diagnostic testing, ECU diagnostic behaviors are defined through a structured configuration file, an independent state set is established for each diagnostic service program connection, and a response is generated by adopting a secondary matching mechanism and a function addressing processing engine. According to the scheme, multi-program parallel independent testing is supported, scenes can be flexibly switched without code modification, physical and functional addressing is completely covered, the defects of hard code modification difficulty, state management globalization and the like in the prior art are overcome, and the testing efficiency and flexibility are improved.

A wearable monitor is configured for early detection of internal bleeding events and particularly hematomas after vascular catheterization including cardiac catheterization. The wearable monitor is placed over an access location following the vascular catheterization procedure and the wearable monitor system periodically runs diagnostic test to detect changes in the tissue around the vascular access location. An emitter device may input an emitter input into the tissue and a detector device may then measure the emitter input after it has passed through the tissue, an emitter output. A computer may receive the data from the detector device and operate a program that determines changes in the tissue and in particular, pooling of blood in the tissue. The emitters may be electrodes that input an electromagnetic input, or an ultrasound emitter that inputs ultrasound sound waves, or a Near IR emitter that emits Near IR electromagnetic radiation.

In alternative embodiments, the invention provides vaccines, pharmaceutical compounds and formulations for diagnosing, preventing, treating or ameliorating Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections. In alternative embodiments, the invention provides compositions such as diagnostic tests, assays, immunoassays and test strips, and methods, for detecting or diagnosing the presence of a Streptococcal infection, e.g., Group A Streptococcus (GAS), Group C Streptococcus (GCS), or Group A Streptococcus (GGS), infections, or other pathogenic Streptococcus infections.

Based on experimental data, observed i n the Personalized Medicine Laboratory of the requesting institute, which reveal an increase in the inorganic polyphosphate (iPolyp) in fecal samples from subjects affected by colorectal cancer compared to samples from individuals not affected by the same disease, inorganic polyphosphate is suggested as a novel non-invasive biomarker to be detected in fecal samples for the early diagnosis of colorectal cancer, to be associated with other screening methods such as fecal occult blood, in order to provide greater predictivity, i.e., the probability that a subject with a positive diagnostic test is actually affected by colorectal cancer.

The present invention relates to anti-CLEC12A antibodies and the antigen-binding fragments thereof. The present invention further relates to pharmaceutical compositions and diagnostic tests comprising the anti-CLEC12A antibodies or antigen binding fragments thereof, and the uses of such antibodies for the treatment and diagnosis of microbial infections.

The invention discloses a respiratory nursing, diagnosis and detection device for the pneumology department, and belongs to the technical field of medical instruments, the respiratory nursing, diagnosis and detection device comprises a respirator, the outer wall of the respirator is communicated with an oxygen connector used for introducing oxygen, an electric push rod is fixedly installed on the outer wall of the respirator and located below the oxygen connector, and an electric push rod is fixedly installed on the inner side of the respirator. A gooseneck pipe is arranged corresponding to the telescopic end of the electric push rod, the other end of the gooseneck pipe is connected with a first spring seat, exhaled gas is directly discharged through the independent first output pipe to be detected, mixing dilution of the exhaled gas and inhaled oxygen is effectively prevented, the purity of an exhaled gas sample is guaranteed, and the exhaled gas sample can be accurately detected. Therefore, the accuracy of the analysis result of the gas sensor is improved, a piston cylinder disinfection mechanism integrated with automatic disinfection and pollution residue prevention is adopted, disinfection gas can be automatically sucked and pushed after each time of use, a nose connector and a sampling pipeline are sterilized, and cross contamination caused by bacterial virus reproduction to subsequent detection is avoided.

The present disclosure pertains to a method of predicting a molecular subtype of a tumor of a subject by (1) receiving preoperative imaging data of the tumor; (2) extracting one or more features of the imaging data; and (3) correlating the extracted features of the imaging data to a molecular subtype of the tumor. The methods may also include steps of outputting the molecular subtype of the tumor and implementing a treatment decision. The present disclosure also pertain to a computing device and a diagnostic test for predicting a molecular subtype of a tumor of a subject in accordance with the aforementioned methods.

A diagnostic system for a vehicle comprises diagnostic modules that implement respective diagnostic tests on the vehicle based on whether specific sets of conditions are met; and an arbitration module that (i) receives requests generated by the diagnostic modules to execute the diagnostic tests, (ii) determines priority levels for the diagnostic tests, and (iii) based on these priority levels, generates one or more diagnostic responses that indicate permission to execute at least one of the diagnostic tests with the highest priority level and deny permission to execute at least one other diagnostic test. In response to the indicated permission, one or more of the diagnostic modules execute the at least one diagnostic test before executing the at least one other diagnostic test.

Systems and methods are disclosed for processing digital images to identify diagnostic tests, the method comprising receiving one or more digital images associated with a pathology specimen, determining a plurality of diagnostic tests, applying a machine learning system to the one or more digital images to identify any prerequisite conditions for each of the plurality of diagnostic tests to be applicable, the machine learning system having been trained by processing a plurality of training images, identifying, using the machine learning system, applicable diagnostic tests of the plurality of diagnostic tests based on the one or more digital images and the prerequisite conditions, and outputting the applicable diagnostic tests to a digital storage device and / or display.

In one embodiment, there is provided a device for performing a plurality of respiratory diagnostic tests, comprising: a housing, a sensor assembly, and control circuitry configured to receive signals from the sensor assembly; wherein the device has a first configuration in which the device is configured to perform a first respiratory diagnostic test and a second configuration in which the device is configured to perform a second respiratory diagnostic test, wherein in the first configuration an airflow channel is defined through the device housing, the sensor assembly being configured to measure at least a first property of air in the airflow channel during the first respiratory diagnostic test, and wherein in the second configuration the airflow channel is modified relative to the first configuration, the sensor assembly being used to measure at least a second property of air in the airflow channel during the second respiratory diagnostic test. In another embodiment there is provided a stand-alone device is designed for performing an impulse oscillometry test.

A method and manufacturing apparatus (110) for manufacturing a plurality of diagnostic test elements (112) comprising at least one core tape (114) and at least one support foil tape (116). The method can be used to manufacture a plurality of analytical test elements for lateral flow assays used in the field of medical diagnostics for detecting one or more properties of a sample of a bodily fluid, such as the presence and / or concentration of at least one analyte in the sample of the bodily fluid. However, other fields of application of the invention are also feasible.

Embodiments of the present application provide a LIN diagnostic test method, an electronic device and a storage medium. The method comprises: sending a diagnostic request message to a target LIN node by a domain controller; if the node address is the same as the target node address of the target LIN node and the data identifier is the same as the target data identifier of the target LIN node, determining whether the LIN controller of the target LIN node supports long frames; if the LIN controller supports long frames, sending a first frame of diagnostic response message after a first delay time; sending a continuous frame of diagnostic response message after a second delay time; and when the sending of the diagnostic response message is completed, if the data identifier in the diagnostic response message is the same as the target data identifier and the response value in the diagnostic response message matches the expected LIN diagnostic response value, determining that the diagnostic service of the domain controller is qualified. Through pre-configuring LIN diagnostic test parameters and pre-designing a LIN diagnostic test method, embodiments of the present application realize full-automatic domain controller LIN diagnostic testing, and effectively improve the test efficiency and reliability.

This disclosure relates to method and system for implementing safety mechanism in vehicles. The method may include determining a fault parameter corresponding to a hazardous fault occurring in a vehicle. The method may include determining a set of safety requirements, mapped to the error parameter. The method may include identifying at least one diagnostic tests based on a mapping of set of safety requirements and the corresponding error parameter with at least one test identifiers from a plurality of test identifiers created for a plurality of diagnostic tests. The method may further include executing at least one diagnostic tests to determine a predefined component identifier corresponding to a faulty component. The method may further include at least one safety mechanism and at least one safety command associated to the faulty component. The method may include implementing the at least one safety mechanism and the at least one safety command.

The invention provides a temperature self-adaptive adjusting method and system of an eMMC memory, and belongs to the technical field of embedded memories. Comprising the following steps: acquiring a real-time temperature and a temperature change rate of an eMMC memory; when the temperature change rate does not exceed a change rate threshold value, executing a corresponding parameter adjustment strategy according to the change condition of a preset temperature interval where the real-time temperature of the eMMC memory is located; after the parameters are adjusted, a diagnosis test link is operated, the performance of the eMMC memory under the current parameters is evaluated, and the current configuration is selectively effective according to a performance evaluation result; and when the temperature change rate exceeds a change rate threshold value, directly interrupting a current process to enter a quick response process, skipping a diagnostic test link and directly applying predefined conservative parameters to the eMMC memory regardless of the real-time temperature of the eMMC memory until the temperature change rate returns to normal or maintains the lowest performance level.

This invention enables increased throughput of diagnostic tests, doubling, tripling, or even further the number of tests per cartridge, and is therefore considered highly environmentally and ecologically friendly. Simultaneously, it provides multiple potentially life-saving test results for one or more patients. The present invention relates to an in vitro diagnostic (IVD) testing system (1a, 1b) for performing multiple diagnostic assays, wherein the IVD testing system (1a, 1b) comprises: a test carrier (2) including a sample application port (3) configured to receive a sample fluid (30); a test region (4) including a common recessed assay membrane region (4a) and a sample release port (4b) for releasing at least one portion (30, 30a) of the sample fluid (30) into the common recessed assay membrane region (4a); and a microfluidic sample channel system (5) configured to guide the at least one portion (30, 30a) of the sample fluid (30) from the sample application port (3) to the sample release port (4b); the IVD testing system (1a, 1b) further comprises: a first assay membrane (6) positioned in the common recessed assay membrane region (4a) and configured to release the sample fluid (30) from the sample application port (3) into the sample release port (4b). The sample release port (4b) receives a first portion of the at least one (30, 30a) of the sample fluid (30) and indicates at least one first analyte (31a) in the first portion of the at least one (30, 30a) of the sample fluid (30); and a second assay membrane (7) is positioned adjacent to the first assay membrane (6) in the common recessed assay membrane region (4a) and is configured to receive a second portion of the at least one (30, 30a) of the sample fluid (30) from the sample release port (4b) and indicate at least one second analyte (31b) in the second portion of the at least one (30, 30a) of the sample fluid (30) and / or indicate at least one first analyte (31a) in the second portion of the at least one (30, 30a) of the sample fluid (30) with a sensitivity range different from that of the first assay membrane (6).

Provided herein are methods, kits and systems for the detection of Brucella antigen, method for detecting brucellosis in a mammal comprising the steps of: obtaining or having obtained a biological sample suspected being infected with Brucella sp.; and detecting in the biological sample immunogenic protein DUF883 or anti-DUF883 antibodies, wherein the presence of DUF883 or anti-DUF883 antibodies are indicative that the mammal has been exposed to Brucella, e.g., to a vaccine or immunogenic composition comprising: immunogenic protein DUF883 provided in an amount sufficient to trigger an immune response against the immunogenic protein; and a pharmaceutically acceptable vaccine carrier.

A disclosed computing device capable of achieving high data rates in link diagnostic testing by replicating traffic may include (1) a packet forwarding device configured to generate, as part of a link diagnostic test, traffic that falls below a certain threshold by a deficit and (2) a packet replication device configured to (A) receive at least a portion of the traffic from the packet forwarding device and (B) replicate the portion of traffic to generate supplemental traffic that compensates for the deficit, and (3) an interface configured to transmit the traffic and the supplemental traffic to a remote device via a link as part of the link diagnostic test. Various other apparatuses, systems, and methods are also disclosed.

The invention discloses a DSM fault diagnosis test method and device and a medium, and the method comprises the steps: constructing a CANoe test environment, and generating a test case for testing a DSM fault diagnosis program; executing a fault clearing operation through a fault clearing program in the ECUTEST software to clear all historical fault codes stored in the VCU controller before the test case simulates a new fault state, so that the VCU controller is in a single fault code state; based on the single fault code state, running the test case through a CANoe test environment; and obtaining a fault diagnosis message sent by the DSM fault diagnosis program in response to the test case, and comparing an actual fault code in the fault diagnosis message with an expected fault code in the test case to generate a diagnosis test report.

Diagnostic assays can use the disclosed cartridge tray assemblies to run tests to identify disease states and physiological conditions. The disclosed cartridge tray assemblies include a cartridge with an interior cavity, a substrate upon which the assay diagnostic test occurs, and an applicator guide. The substrate is positioned within the interior cavity of the cartridge and has a fixed sample application location at which a prepared sample is applied for the diagnostic assay. The applicator guide has a channel that is aligned above and spaced apart from the fixed sample application location of the substrate to help apply the prepared sample in a precise and accurate location on the substrate.