2856 results about "Skin surfaces" patented technology

Systems, devices and methods are provided for stimulating one or more nerves within a user. A system comprises stimulator having an electrode configured for contacting the outer skin surface at a target location and an energy source coupled to the stimulator, The energy source is configured to generate at least one electrical impulse and to transmit the electrical impulse transcutaneously from the electrode through the outer skin surface of the user to a selected nerve in the user. In certain aspects, the systems and methods are particularly useful for non-medical purposes, such as reducing stress and anxiety, enhancing relaxation, improving sleep, energy, concentration and mood, increasing mental or physical performance, promoting mental health, recovery and wellness, generally improving the health and wellbeing of a user and / or for temporarily or permanently improving intelligence, learning capacity, memory retention, recall, mood, alertness and / or sleep efficiency in human beings.

An angled intraosseous access system including a guide block and / or a guide plate is disclosed. The system includes a driver having a body, and including a needle assembly rotatably coupled thereto, the needle assembly defining a needle axis. One of the guide block or the guide plate is configured to engage a skin surface and align the needle assembly axis at a predetermined angle relative to the skin surface to access the medullary cavity at the predetermined angle. Advantageously, the angled needle of the intraosseous access system can mitigate pain during infusion and mitigate backwalling.

According to some embodiments, a microdermabrasion device for treating skin comprises a handpiece assembly having a distal end and a proximal end. The handpiece assembly includes at least one delivery conduit and at least one waste conduit. The microdermabrasion device additionally comprises a tip configured to be positioned along the distal end of the handpiece assembly, wherein the tip is adapted to contact skin surface. In several embodiments, the tip comprises a lip, a first opening in fluid communication with the fluid delivery conduit and a second opening in fluid communication with the waste conduit. In one embodiment, the device includes one or more abrasive elements positioned along a distal end of the tip, wherein the abrasive elements are configured to selectively remove skin as the tip is moved relative to a skin surface.

A process for exfoliating the skin, including the scalp, and / or the nails, comprising the step consisting in subjecting a surface of said skin (K), or said nails, to a cosmetic composition and to ultrasonic acoustic waves emitted by a device comprising at least one ultrasonic transducer (13), with an acoustic intensity Isata in the region exposed to the acoustic waves that is at least equal to 0.1 W / cm2, i) the transducer being moved relative to said surface at an average sweeping speed of between 0.01 cm2 / s and 15 cm2 / s for the duration of treatment of said surface, and / or ii) the device being applied to a location on the keratin material, then moved away from the latter and applied to a different location.

The invention provides an editable digital human modeling method and device based on neural texture and three-dimensional Gaussian, and the method comprises the steps: carrying out the modeling of the expression, posture and appearance of a digital human through a three-dimensional Gaussian splashing model according to the motion sequence video data of a target object, and obtaining a Gaussian model of the digital human; modeling the expression, posture and appearance of the digital human through the neural texture model to obtain a neural texture model of the digital human; pruning the Gaussian model, and performing hybrid rendering according to a rendered image output by the pruned Gaussian model and a rendered image output by the neural texture model of the digital human to obtain a hybrid rendered image; and optimizing a Gaussian model of the digital human based on the mixed rendered image and the action sequence video data to obtain an editable digital human model. According to the method, the storage overhead and the structural complexity of the digital human model are reduced, and the high-frequency details and editing efficiency of the skin surface of the digital human model are improved.

The invention provides a blood glucose monitoring and early warning method. The blood glucose monitoring and early warning method comprises the steps of a, collecting a skin surface spectral signal I (lambda), b, collecting skin surface temperature T, humidity H, environment light intensity L and environment electromagnetic interference E parameters, c, preprocessing the spectral signal I (lambda), removing noise N (I) through wavelet transform, and d, calculating the blood glucose monitoring and early warning parameters. And the signal intensity is corrected through an ambient light intensity compensation model. According to the blood glucose monitoring and early warning method, a non-invasive acquisition mode combining near infrared spectrum and visible light spectrum is adopted, and a multi-modal regression model and a dynamic interference compensation technology are innovatively introduced, so that the problem that the precision of a sensor is influenced by skin temperature, humidity and environmental electromagnetic interference in the prior art is solved; the timeliness and the stability of signal purification are improved by utilizing preprocessing and optimization algorithms of spectral signals, such as wavelet transform, empirical mode decomposition and fast Fourier transform.

According to some embodiments, a method of promoting hair growth or hair stimulation in a subject comprises applying vacuum or suction using a handpiece assembly along a targeted portion of the subject's skin surface where hair growth or hair stimulation is desired and providing at least one treatment material to said targeted portion of the subject's skin surface, wherein the application of vacuum or suction helps promote hair growth or stimulate hair.

According to some embodiments, a method of treating a skin surface of a subject comprises heating a skin surface, abrading native skin tissue of a subject using a microdermabrasion device, wherein using the microdermabrasion device comprises moving the microdermabrasion device relative to the skin surface while simultaneously delivering at least one treatment fluid to the skin surface being treated and cooling the abraded skin surface.

A system that can deliver haptic feedback by applying an electrical stimulation to a first area of a user's body to induce a second area of the user's body to experience a level of natural sensation in response to an action occurring in a simulated remote environment and an intensity of the action is described. The system includes a controller to set parameters for the electrical stimulation based on the action occurring in the simulated remote environment and an intensity of the action. The system also includes a signal generator to generate the electrical stimulation comprising the parameters. The system also includes a skin surface electrode placed at a first location on a user's body remote from a second location on the user's body to deliver the electrical stimulation with the parameters to a nerve at or near the first area of the user's body.

The invention discloses a closed-loop noninvasive spinal cord electrical stimulation regulation and control method and system based on motion data, and the system is provided with a flexible electrode array patch which is attached to the skin surface of a to-be-tested human body; the sensing module is used for collecting electromyographic signals or acceleration signals of a user; the signals are processed, and characteristic values related to actions and motions are extracted; the closed-loop feedback module compares the characteristic value with a model set characteristic / threshold value, and judges whether to start stimulation site and stimulation parameter adjustment or not; automatically selecting an optimal electrode unit and a corresponding stimulation parameter based on a judgment result; the dynamic regulation and control module controls the optimal electrode unit to output stimulation current, and regulates the activity of corresponding spinal cord neurons; and continuously performing closed-loop adjustment on the electrode unit and the stimulation parameters according to the motion feedback data. According to the method and system, precise stimulation and closed-loop regulation and control based on the motion response of the patient are achieved, and the problems that stimulation target positioning depends on artificial experience, parameter adjustment is not timely, and individualized and closed-loop feedback capacity is lacked are solved.

According to an aspect, there is provided a personal care device (2) for performing a personal care operation on a subject, the personal care device (2) being configured to determine a location of the personal care device (2) on a body part of the subject. The personal care device (2) comprises an orientation sensor (6) configured to measure a three-dimensional, 3D, angular orientation of the personal care device (2) relative to Earth's gravity over time and output a corresponding orientation measurement signal; a surface-displacement sensor (10) configured to measure a two-dimensional, 2D, displacement of the personal care device (2) relative to a skin surface of the body part and output a corresponding surface-displacement measurement signal; a processing unit (22) configured to determine the location of the personal care device (2) on the body part based on the orientation measurement signal, the surface-displacement measurement signal and a skin contact signal indicating whether the personal care device (2) is in contact with the skin surface of the body part.

According to some embodiments, a skin treatment assembly comprises a handpiece comprising a distal end, the handpiece comprising a recess or cavity configured to receive a cartridge or other fluid container, a tip configured to be positioned along the distal end of the handpiece, the tip being configured to contact a skin surface of a subject during use, and at least one rollerball configured to extend to or near the tip, wherein the rollerball is configured to be in fluid communication with an interior of a cartridge or other fluid container secured to the handpiece, wherein the at least one rollerball is configured to contact the skin surface of the subject during use and to facilitate the delivery of fluids to said skin surface as the rollerball is moved relative to said skin surface.

Ultrasound probes, ultrasound systems, and ultrasound methods with pressure measurement capabilities for detecting and determining if bodily tissue is over-compressed during ultrasound imaging procedure. An ultrasound probe can include a probe body, an articulating probe head attached to the probe body, and a pressure-sensing device housed in an articulating area between the articulating probe head and the probe body. A method can include placing the articulating probe head of the ultrasound probe on a skin surface of a patient and moving the articulating probe head of the ultrasound probe over the patient while ultrasound signals are emitted into the patient from the articulating probe head. The method can also include monitoring for measured pressure values induced on the patient by the articulating probe head to determine whether a threshold pressure value has been exceeded.

The utility model discloses a multifunctional warp-knitted ice-feeling heat-shielding sunscreen fabric which comprises first yarn and second yarn, the first yarn is full-dull special-shaped section chinlon filaments with the specification of FDY45Dtex / 48F, and the second yarn is high-temperature-resistant spandex filaments with the specification of 40dTEX. The first yarns and the second yarns are separately perforated for weaving, so that the first yarns cover the second yarns, namely, the first yarns are exposed on the inner side, and as the first yarns adopt the chinlon filaments with cool feeling, when the fabric body is in contact with the skin of a human body, the first yarns are in contact with the skin of the human body; the first yarns with larger areas are in contact with the skin of a human body, so that a better cool feeling is kept; moreover, the first yarns and the second yarns are thin, so that the fabric body is thin, and the air permeability is good; moreover, due to the fact that the first yarn and the second yarn are woven in a high-density mode, the density of the fabric body is high, ultraviolet rays are not prone to penetrating through the fabric body, and the sunscreen effect is achieved.

The present disclosure provides a target region positioning method, an electronic device and a computer readable storage medium, the target region positioning method comprising: acquiring, by a camera, a target image comprising a skin surface region corresponding to a reaction bone; wherein the reaction bone is a bone having a target feature; identifying the skin surface region from the target image; determining first device coordinate information of a center position of the skin surface region in a device coordinate system; determining second device coordinate information of a center position of a target region comprising a lesion in the device coordinate system according to the first device coordinate information and predetermined first position relationship information; wherein the first position relationship information is position relationship information between the center position of the skin surface region and the center position of the target region.

The present invention relates to a treatment apparatus using RF energy, a method for controlling same, and a treatment method using same. More particularly, the present invention provides a treatment apparatus using RF energy, a method for controlling same, and a treatment method using same, the treatment apparatus comprising: a handpiece having an electrode configured to contact a skin surface and to transfer RF energy; an RF energy-generating unit for generating RF energy to be transferred to the electrode; a cooling unit provided to cool the electrode; and a control unit for controlling the operations of the RF energy-generating unit and the cooling unit and controlling the cooling unit so as to preliminarily cool the electrode before RF energy is applied to the electrode.

A method for mid-intensity non-ablative acoustic treatment of injured tissue is disclosed. The method involves continuously moving an ultrasound probe across an extracorporeal skin surface while emitting non-ablative therapeutic ultrasound into the injured tissue in a non-ablative therapeutic ultrasound beam profile. The method terminates energy delivery if movement speed is below a speed threshold. The non-ablative therapeutic ultrasound beam profile provides substantially uniform heating throughout a treatment volume. The heating is non-ablative and triggers a healing response in the injured tissue.

The invention relates to the technical field of human body temperature prediction, and provides a human body skin temperature prediction method and system fusing an informer and STGCN. The method comprises the following steps: according to a topological structure among a plurality of measurement points of acquired skin temperature data of a target object, based on a space-time diagram convolutional network, extracting space time sequence characteristics of the measurement points, and based on a first informer module of a self-attention mechanism, respectively according to a data matrix of the skin temperature data and a data matrix of acquired environmental parameter data; respectively extracting temperature time sequence characteristics and environment time sequence characteristics of the measurement points; and then, fusing the space time sequence characteristics, the temperature time sequence characteristics and the environment time sequence characteristics of the measurement points in a second informer module based on a self-attention mechanism according to a time sequence, inputting an obtained characteristic matrix into a full-connection neural network, and predicting the skin temperature of a target measurement point.

A system for detecting an anomalous biologic event in a person includes a wearable device for monitoring skin surface sites of a person. The wearable device includes an electrode for contacting skin sites, an electronic stimulus source with a surface area to provide stimulus, and a sensor placed adjacent the skin sites to sense physiological data. A processor is coupled to the wearable device and is configured to: cause the stimulus source to generate a stimulus; excite the electrode to trigger monitoring the skin sites; cause operation of the sensor; receive bioelectrical data from each skin site; receive physiological data from the sensor; continuously compute a difference in the received bioelectrical data for a duration; compute a difference in the received physiological data at time intervals; and generate, based on the computation, an assessment including a likelihood of occurrence of the anomalous biologic event.

The invention discloses a part digital twin surface model rapid characterization method based on virtual-real fusion, and the method comprises the steps: inputting a part design CAD model and a manufacturing solid model, and obtaining the surface feature information of the CAD model and the high-precision point cloud data of the corresponding surface of the solid model; a mechanism modeling method and a data analysis method are adopted to obtain a standard skin shape model and an authenticated skin shape model respectively; after the two skin shape models are preprocessed, a training sample set is formed through virtual-real fusion, and a deep learning model based on a generative adversarial network is constructed and used for generating a surface three-dimensional deviation form unit model meeting functional requirements; and establishing correlation mapping between the CAD ideal surface model of the part and the three-dimensional deviation form of the CAD ideal surface model to obtain a training skin surface shape model, and taking the training skin surface shape model as the representation of the digital twin surface model of the part. According to the method, the precision and efficiency of part surface feature skin surface model expression are improved, and the method can be suitable for assembly precision analysis and prediction simulation of digital twin-driven precision mechanical and electrical products.

The invention belongs to the field of synthetic biology, and particularly relates to collagen fusion polypeptide as well as application and a preparation method thereof. The collagen fusion polypeptide provided by the invention comprises: (a) a first polypeptide of recombinant III-type collagen; and (b) a second polypeptide comprising a trimerized folding domain. The collagen fusion polypeptide provided by the invention has the advantages of low immunogenicity, good biocompatibility, high biological activity and the like, can significantly promote proliferation and migration of human skin fibroblasts, and has stronger ability of promoting regeneration of endogenous collagen. The collagen fusion polypeptide has a triple helix structure similar to natural collagen, and can be self-assembled to form collagenous fibers which are good in morphology and similar to natural collagen. The method can be widely applied to the fields of skin repair dressings, biological materials, artificial implants, medical instruments, cosmetics, health care products, food and the like.

The invention relates to an extraction electrode voltage determining method, device and system, a continuous blood glucose monitoring device comprises an extraction electrode, the extraction electrode is attached to the skin surface of a user, and the method comprises the steps that first loading voltage of the extraction electrode is obtained; under the condition that the extraction electrode is loaded with the first loading voltage, the current value of first current flowing through the skin surface of the user is determined; and when the current value of the first current is within a preset current value range, determining the first loading voltage as the loading voltage for an extraction electrode to extract the tissue fluid of the corresponding user.

The invention relates to a wearable aptamer electrochemical sensor and a preparation method and application thereof, and belongs to the field of wearable sensors, and the preparation method comprises the following steps: 1) preparing an electrochemical sensing unit on a flexible substrate, including a TNF-alpha working electrode, a sodium ion working electrode and a pH working electrode; 2) preparing a microfluidic layer with a sweat detection channel; and 3) combining the flexible substrate with the microfluidic layer, and correspondingly fitting the electrochemical sensing unit with the sweat detection channel so as to monitor TNF-alpha, sodium ions and pH in sweat. By adopting the overall flexible design, the sweat TNF-alpha monitoring device is suitable for noninvasive and dynamic monitoring of human body inflammatory factors in a resting state, and the accuracy of sweat TNF-alpha monitoring can be improved; the non-invasive monitoring problem of high sensitivity, high specificity, high accuracy and high stability of sweat inflammatory factors in a non-motion state is solved, and the prepared electrochemical sensor can be attached to the surface of human skin and can be further applied to monitoring and management of inflammatory diseases and related fields.

A system for detecting an anomalous biologic event in a person includes a wearable device for monitoring skin surface sites of a person. The wearable device includes an electrode for contacting skin sites, an electronic stimulus source with a surface area to provide stimulus, and a sensor placed adjacent the skin sites to sense physiological data. A processor is coupled to the wearable device and is configured to: cause the stimulus source to generate a stimulus; excite the electrode to trigger monitoring the skin sites; cause operation of the sensor; receive bioelectrical data from each skin site; receive physiological data from the sensor; continuously compute a difference in the received bioelectrical data for a duration; compute a difference in the received physiological data at time intervals; and generate, based on the computation, an assessment including a likelihood of occurrence of the anomalous biologic event.

The invention discloses a respiration monitoring system based on a flexible strain sensor and a monitoring analysis method, and belongs to the technical field of sensors and respiration monitoring equipment. The respiration monitoring system comprises a flexible strain sensor, a connecting line, a data acquisition card and an upper computer; the flexible strain sensor is a band-aid type flexible strain sensor and can be directly adhered to the skin surface of a human body, and the deformation of muscles related to respiration is monitored and converted into the change of a resistance signal. And the flexible strain sensor is connected with the data acquisition card through a connecting line. And the data acquisition card is connected with the upper computer and is used for transmitting the acquired resistance signals to the upper computer. The quantitative breathing mode judgment standard is provided through dynamic measurement of the respiratory muscle group, and the defect that judgment is mainly conducted through naked eyes of doctors for a long time can be overcome; the relation between the respiratory muscle group deformation and the lung function parameters is associated, and the problem that the actual respiration condition of part of patients does not conform to the detection condition in conventional lung function detection can be solved.

The invention provides a male product delay spray and a preparation process thereof, and relates to the field of delay sprays. The preparation process of the male product delayed spray comprises the following steps: S1, preparing water and ethanol, and uniformly stirring and mixing; s2, extracting fructus cnidii, herba epimedii, flos caryophylli, pericarpium zanthoxyli, herba cistanche, herba cynomorii and piper nigrum respectively; s3, obtaining a corresponding extract according to the step S2; s4, putting the obtained extract into water and an ethanol dissolving solution; s5, increasing the stirring speed, heating, and fully dissolving and mixing; s6, stopping stirring and cooling to room temperature; and S7, performing filling. According to the invention, the plant extract is adopted as an effective component, and the special pepper kava extract is selected, so that the irritation can be obviously reduced, the delay effect can be obviously improved, and the effects of reducing the skin sensitivity of the penis and improving the sexual intercourse time can be achieved by applying the plant extract to the skin surface of the male penis.

A sensor patch for attachment to the adhesive surface of a base plate of an ostomy appliance is disclosed. The sensor patch has a proximal surface for attachment to the skin surface of a user and a distal surface for attachment of the sensor patch to the adhesive surface of a base plate. The sensor patch comprises an adhesive layer having a proximal side including a proximal surface for adhering the sensor patch to the skin, and a distal side including a distal surface; and a sensing layer comprising a nonwoven substrate and electrical conductors, the sensing layer arranged on the distal side of the adhesive layer, the sensing layer having a proximal side including a proximal surface and a distal side including a distal surface, the sensing layer being liquid permeable.

The invention provides an anti-aging repair composition containing PDRN, and lipid nanoparticles and application thereof. The composition provided by the invention is prepared from polydeoxyribonucleotide, micro-current tetrapeptide-1 and palmitoyl tripeptide-5. According to the application, the polydeoxyribonucleotide, the micro-current tetrapeptide-1 and the palmitoyl tripeptide-5 are compounded for use, so that the composition has a synergistic effect in the aspects of promoting cell proliferation, inhibiting an intracellular ROS (reactive oxygen species) level and the like, and has remarkable antioxidant, anti-inflammatory, anti-aging, soothing and repairing effects. The PDRN-containing composition is prepared into the lipid nanoparticles, so that the stability of the PDRN-containing composition is improved, the permeability of the PDRN-containing composition on the skin surface is improved, the bioavailability of the PDRN-containing composition is improved, the cell survival rate and cell uptake are promoted, the expression of adenosine A2A receptors, the synthesis of collagen, angiogenesis and the inhibition of anti-inflammatory factors are promoted, and a remarkable anti-aging effect is achieved.

The present invention discloses an AI-based automatic acupoint recognition and positioning system and method, the system comprises an AI server, an image acquisition device, a body shape recognition and comparison module, an AI acupoint recognition module and an acupoint projection module; the AI ​​server is used to establish at least one sample model according to a pre-collected three-dimensional image of a human body shape, wherein the three-dimensional image of the human body shape contains acupoint marking points of various parts of the human body; the image acquisition device is used to collect a three-dimensional target image of the patient's body shape when the positions of various acupoints on the patient's body need to be positioned; the body shape recognition and comparison module is used to compare the three-dimensional target image with multiple three-dimensional images of human body shapes of at least one sample model in the AI ​​server to determine whether the three-dimensional target image can match the size ratio of any three-dimensional image of human body shape; the AI ​​acupoint recognition module uses the matched three-dimensional image of human body shape as a reference to determine the positions of acupoints of various parts of the patient's body; the acupoint projection module is used to project the acupoint marking points of various parts of the human body displayed by the matched three-dimensional image of human body shape to various positions on the patient's body skin surface. Effect: AI technology can quickly and accurately locate acupoints, can adapt to different groups of people, can realize the visualization and intuition of acupoint positioning, and can more easily help people who need to quickly and accurately locate acupoints.

The invention provides a recombinant humanized elastin with high biological activity as well as a preparation method and application thereof, and belongs to the technical field of genetic engineering and biological materials. 100% of the amino acid sequence of the elastin is derived from human elastin and is prepared by expression of genetically engineered bacteria; the protein has a typical beta-spiral hydrophobic structural domain and a lysine-rich hydrophilic structural domain, has a good bionic structure and functional characteristics, can significantly promote proliferation, adhesion and migration of human skin fibroblasts, also has excellent antioxidant, anti-wrinkle and anti-aging activities, and can be used for preparing a biomimetic protein. The hydrogel can be widely applied to the fields of skin repair dressings, injection implants, artificial skin, biomedical materials, functional skin care products and the like; in addition, the elastin is good in solubility, high in stability, mature in expression system and suitable for large-scale production.