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1112 results about "Adipose tissue" patented technology
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In biology, adipose tissue, body fat, or simply fat is a loose connective tissue composed mostly of adipocytes. In addition to adipocytes, adipose tissue contains the stromal vascular fraction (SVF) of cells including preadipocytes, fibroblasts, vascular endothelial cells and a variety of immune cells such as adipose tissue macrophages. Adipose tissue is derived from preadipocytes. Its main role is to store energy in the form of lipids, although it also cushions and insulates the body. Far from being hormonally inert, adipose tissue has, in recent years, been recognized as a major endocrine organ, as it produces hormones such as leptin, estrogen, resistin, and cytokine (especially TNFα). The two types of adipose tissue are white adipose tissue (WAT), which stores energy, and brown adipose tissue (BAT), which generates body heat. The formation of adipose tissue appears to be controlled in part by the adipose gene. Adipose tissue – more specifically brown adipose tissue – was first identified by the Swiss naturalist Conrad Gessner in 1551.
Method and apparatus for non-invasive body contouring by lysing adipose tissue
A method and apparatus for producing lysis of adipose tissue underlying the skin of a subject, by: applying an ultrasonic transducer to the subject's skin to transmit therethrough ultrasonic waves focussed on the adipose tissue; and electrically actuating the ultrasonic transducer to transmit ultrasonic waves to produce cavitational lysis of the adipose tissue without damaging non-adipose tissue.
Owner:ULTRASHAPE INC +1
Methods and devices for detection and control of selective disruption of fatty tissue during controlled cooling
ActiveUS20050251120A1Ultrasonic/sonic/infrasonic diagnosticsSkeletal/connective tissue cellsMedicineAdipose tissue
Owner:THE GENERAL HOSPITAL CORP
Systems and methods for the destruction of adipose tissue
InactiveUS20050154431A1Ultrasonic/sonic/infrasonic diagnosticsChiropractic devicesEnergy applicatorTransducer
Described is a system and method for the destruction of adipose tissue using an energy applicator such as a HIFU transducer. The system has a scan head containing an energy applicator, a mechanical arm for carrying the weight of the scan head, and a therapy controller such as a computer for controlling the operation of the scan head. The therapy controller may be part of a general purpose computer, and may be used as a robotic controller to automate the procedure. Methods are included for destroying adipose tissue in a quick, non-invasive manner.
Owner:LIPOSONIX
Apparatus and method for disrupting subcutaneous structures
InactiveUS20070060989A1Improve breathabilitySelective disruptionUltrasound therapyElectrotherapyDiseaseCellulite
Methods and apparatus are provided for disruption / destruction of subcutaneous structures in a mammalian body for the treatment of skin irregularities, and other disorders such as excess adipose tissue, cellulite, and scarring. Devices and methods include energy mediated applicators, microneedles, catheters and subcutaneous treatment devices for applying a treatment non-invasively through the skin, less invasively through the skin, or minimally invasively via a subcutaneous approach. Various agents to assist or enhance the procedures are also disclosed.
Owner:THE FOUNDRY INC
Systems and methods for separating and concentrating regenerative cells from tissue
ActiveUS20050084961A1High yieldImprove consistencyBioreactor/fermenter combinationsBiocideBiomedical engineeringAdipose tissue
Systems and methods are described that are used to separate cells from a wide variety of tissues. In particular, automated systems and methods are described that separate regenerative cells, e.g., stem and / or progenitor cells, from adipose tissue. The systems and methods described herein provide rapid and reliable methods of separating and concentrating regenerative cells suitable for re-infusion into a subject.
Owner:LOREM VASCULAR PTE LTD
Use of adipose tissue-derived stromal cells for chondrocyte differentiation and cartilage repair
Methods and compositions for directing adipose-derived stromal cells cultivated in vitro to differentiate into cells of the chondrocyte lineage are disclosed. The invention further provides a variety of chondroinductive agents which can be used singly or in combination with other nutrient components to induce chondrogenesis in adipose-derived stromal cells either in cultivating monolayers or in a biocompatible lattice or matrix in a three-dimensional configuration. Use of the differentiated chondrocytes for the therapeutic treatment of a number of human conditions and diseases including repair of cartilage in vivo is disclosed.
Owner:COGNATE BIOSERVICES
Transgenic non-human animals expressing a truncated activintype II receptor
InactiveUS6891082B2Increase myostatin signal transductionReduce and inhibitPeptide/protein ingredientsMuscular disorderMyostatinBrown adipose tissue
The present invention provides a substantially purified growth differentiation factor (GDF) receptor, including a GDF-8 (myostatin) receptor, as well as functional peptide portions thereof. In addition, the invention provides a virtual representation of a GDF receptor or a functional peptide portion thereof. The present invention also provides a method of modulating an effect of myostatin on a cell by contacting the cell with an agent that affects myostatin signal transduction in the cell. In addition, the invention provides a method of ameliorating the severity of a pathologic condition, which is characterized, at least in part, by an abnormal amount, development or metabolic activity of muscle or adipose tissue in a subject, by modulating myostatin signal transduction in a muscle cell or an adipose tissue cell in the subject. The invention also provides a method of modulating the growth of muscle tissue or adipose tissue in a eukaryotic organism by administering an agent that affects myostatin signal transduction to the organism.
Owner:THE JOHN HOPKINS UNIV SCHOOL OF MEDICINE
Apparatus and methods for the destruction of adipose tissue
ActiveUS7857773B2Eliminate and greatly reduce needLimited amountUltrasonic/sonic/infrasonic diagnosticsUltrasound therapySkin colorNon invasive
Methods and apparatus are described for modifying unwanted tissue for cosmetic reasons. The methods provide a non-invasive manner to perform body contouring by destroying adipose tissue while simultaneously causing collagen contraction in a single procedure so that as destroyed tissue is removed from a treatment volume, the volume shrinks gradually to maintain the skin tone of the treatment area.
Owner:SOLTA MEDICAL
Modified and stabilized GDF propeptides and uses thereof
InactiveUS7202210B2Prevent practical therapeuticPrevent prophylactic utilityFungiBacteriaAcute hyperglycaemiaMuscle tissue
Modified and stabilized propeptides of Growth Differentiation Factor proteins, such as GDF-8 and Bone Morphogenetic Protein-11, are disclosed. Also disclosed are methods for making and using the modified propeptides to prevent or treat human or animal disorders in which an increase in muscle tissue would be therapeutically beneficial. Such disorders include muscle or neuromuscular disorders (such as amyotrophic lateral sclerosis, muscular dystrophy, muscle atrophy, congestive obstructive pulmonary disease, muscle wasting syndrome, sarcopenia, or cachexia), metabolic diseases or disorders (such as such as type 2 diabetes, noninsulin-dependent diabetes mellitus, hyperglycemia, or obesity), adipose tissue disorders (such as obesity), and bone degenerative diseases (such as osteoporosis).
Owner:WYETH LLC
Method and device for fat treatment
InactiveUS20110112520A1Good electrode couplingEvenly distributedElectrotherapySurgical instruments for heatingVoltage pulseTissue heating
A method and apparatus for fat destruction and body contouring. The method comprises pre-heating treated tissue and applying a high voltage pulse to destroy adipose tissue. The device includes an energy source for tissue heating and an HV pulse generator for applying voltage pulsed in the range of 200V to 5 kV.
Owner:INVASIX
Systems for electrical stimulation of nerves in adipose tissue regions
Systems provide a stimulation electrode assembly sized and configured for placement in an adipose tissue region to stimulate a nerve in the adipose tissue region comprising an elongated lead sized and configured to be implanted within the adipose tissue region, the lead including at least two electrically conductive portions to apply electrical stimulation to nerve tissue in the adipose tissue region, and at least two expandable anchoring structures deployable from the lead to engage adipose tissue and resist dislodgment and / or migration of the at least two electrically conductive portions within the adipose tissue region.
Owner:MEDTRONIC URINARY SOLUTIONS
Transgenic non-human animals expressing a truncated activin type II receptor
The present invention provides a substantially purified growth differentiation factor (GDF) receptor, including a GDF-8 (myostatin) receptor, as well as functional peptide portions thereof. In addition, the invention provides a virtual representation of a GDF receptor or a functional peptide portion thereof. The present invention also provides a method of modulating an effect of myostatin on a cell by contacting the cell with an agent that affects myostatin signal transduction in the cell. In addition, the invention provides a method of ameliorating the severity of a pathologic condition, which is characterized, at least in part, by an abnormal amount, development or metabolic activity of muscle or adipose tissue in a subject, by modulating myostatin signal transduction in a muscle cell or an adipose tissue cell in the subject. The invention also provides a method of modulating the growth of muscle tissue or adipose tissue in a eukaryotic organism by administering an agent that affects myostatin signal transduction to the organism.
Owner:THE JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE
Ultrasonic treatment and imaging of adipose tissue
InactiveUS20080015435A1Ultrasonic/sonic/infrasonic diagnosticsUltrasound therapyElectricityHuman body
A system for the destruction of adipose tissue utilizing high intensity focused ultrasound (HIFU) within a patient's body. The system comprises a controller for data storage and the operation and control of a plurality of elements. One elements is a means for mapping a human body to establish three dimensional coordinate position data for existing adipose tissue. The controller is able to identify the plurality of adipose tissue locations on said human body and establish a protocol for the destruction of the adipose tissue. A HIFU transducer assembly having one or more piezoelectric element(s) is used along with at least one sensor wherein the sensor provides feed back information to the controller for the safe operation of the piezoelectric element(s). The sensor is electronically coupled to the controller, and the controller provides essential treatment command information to one or more piezoelectric element(s) based on positioning information obtained from the three dimensional coordinate position data.
Owner:LIPOSONIX
Methods for electrosurgical incisions on external skin surfaces
InactiveUS6896672B1Accurate cutMinimal painSurgical instruments for heatingCoatingsCuticleCuldoplasty
Systems and methods are provided for removing fatty tissue underlying a patient's epidermis (e.g., blepharoplasty, brow lifts, eyelid shortening procedures, and the like). These methods include positioning one or more active electrode(s) and one or more return electrode(s) in close proximity to a target site on an external body surface of the patient. A high frequency voltage difference is applied between the active and return electrode(s), and the active electrode(s) are translated across the external body surface to create an incision therein. The bipolar configuration controls the flow of current to within and around the distal end of the probe, which minimizes tissue necrosis and the conduction of current through unwanted paths in the patient. The residual heat from the electrical energy also provides simultaneous hemostasis of severed blood vessels, which increases visualization and improves recovery time for the patient.
Owner:ARTHROCARE
Method and apparatus for selective treatment of biological tissue using ultrasound energy
A method and apparatus are provided for dermatological treatment by focusing ultrasound energy in a volume of tissue below the dermis to obtain selective heating and thermal damage of certain portions of the volume while sparing other portions of the treatment volume from thermal damage. Selective heating of fibrous septae can be achieved while relatively sparing surrounding fatty tissue, which can lead to some shrinkage of the fibrous septae and reduction in the appearance of wrinkles. The matrix of hair follicles can also be selectively heated to provide relatively safe temporary or permanent hair removal. The superficial musculoaponeurotic system can also be selectively heated to obtain a tightening of the overlying skin.
Owner:THE GENERAL HOSPITAL CORP
Ultrasound system and method to deliver therapy based on user defined treatment spaces
InactiveUS20100286518A1Facilitates userUltrasound therapyOrgan movement/changes detectionUltrasound imagingSonification
An ultrasound imaging and therapy system is provided that includes an ultrasound probe and a diagnostic module to control the probe to obtain diagnostic ultrasound signals from a region of interest (ROI) of the patient. The ROI includes adipose tissue and the diagnostic module generates a diagnostic image of the ROI based on the ultrasound signals obtained. The system also includes a display to display the image of the ROI and a user interface to accept user inputs to designate a treatment space within the ROI that corresponds to the adipose tissue. The display displays the treatment space on the image. The system also includes a therapy module to control the probe to deliver, during a therapy session, a therapy to a treatment location based on a therapy parameter. The treatment location is within the treatment space defined by the user inputs.
Owner:GENERAL ELECTRIC CO
Systems and methods for the destruction of adipose tissue
InactiveUS7993289B2Ultrasonic/sonic/infrasonic diagnosticsChiropractic devicesEnergy applicatorTransducer
Described is a system and method for the destruction of adipose tissue using an energy applicator such as a HIFU transducer. The system has a scan head containing an energy applicator, a mechanical arm for carrying the weight of the scan head, and a therapy controller such as a computer for controlling the operation of the scan head. The therapy controller may be part of a general purpose computer, and may be used as a robotic controller to automate the procedure. Methods are included for destroying adipose tissue in a quick, non-invasive manner.
Owner:LIPOSONIX
GASP1: a follistatin domain containing protein
Owner:WYETH LLC
Lead and electrode structures sized and configured for implantation in adipose tissue and associated methods of implantation
ActiveUS20060004429A1Spinal electrodesExternal electrodesElectrical stimulationsBiomedical engineering
Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and / or migration of the electrically conductive portion within the adipose tissue region.
Owner:MEDTRONIC URINARY SOLUTIONS
Endocrine pancreas differentiation of adipose tissue-derived stromal cells and uses thereof
The invention provides cells, compositions and methods based on the differentiation of adipose tissue-derived stromal cells into a cell expressing at least one genotypic or phenotypic characteristic of a pancreas cell. The cells produced in the method are useful in providing a source of differentiated and functional cells for research, implantation, transplantation and development of tissue engineered products for the treatment of diseases of the pancreas and pancreatic tissue repair.
Owner:ARTECEL
Method for affecting urinary function with electrode implantation in adipose tissue
Systems and methods provide a stimulation electrode assembly comprising an elongated lead sized and configured to be implanted within an adipose tissue region. The lead includes an electrically conductive portion to apply electrical stimulation to nerve or muscle in the adipose tissue region and at least one expandable anchoring structure deployable from the lead to engage adipose tissue and resist dislodgment and / or migration of the electrically conductive portion within the adipose tissue region.
Owner:MEDTRONIC URINARY SOLUTIONS
Systems and methods for treating patients with processed lipoaspirate cells
Cells present in processed lipoaspirate tissue are used to treat patients. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of stem cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the stem cells are not exposed to an external environment prior to being administered to a patient. Compositions that are administered to a patient include a mixture of adipose tissue and stem cells so that the composition has a higher concentration of stem cells than when the adipose tissue was removed from the patient.
Owner:LOREM VASCULAR PTE LTD
Methods of using regenerative cells in the treatment of musculoskeletal disorders
Owner:LOREM VASCULAR PTE LTD
Methods of using regenerative cells to promote wound healing
Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.
Owner:LOREM VASCULAR PTE LTD
Energy-based tissue tightening
ActiveUS20130296700A1Easy to seeEasy to identifyUltrasonic/sonic/infrasonic diagnosticsUltrasound therapyEnergy basedThermal treatment
Owner:GUIDED THERAPY SYSTEMS LLC
Noninvasive aesthetic treatment for tightening tissue
ActiveUS20130281891A1Avoid injuring vital structureEasy to seeUltrasonic/sonic/infrasonic diagnosticsUltrasound therapyNon invasiveThermal treatment
Systems and methods for noninvasive tissue tightening are disclosed. Thermal treatment of tissues such as superficial muscular aponeurosis system (SMAS) tissue, muscle, adipose tissue, dermal tissue, and combinations thereof are described. In one aspect, a system is configured for treating tissue through delivery of ultrasound energy at a depth, distribution, temperature, and energy level to achieve a desired cosmetic effect.
Owner:GUIDED THERAPY SYSTEMS LLC
Method and device for soft tissue treatment
InactiveUS20060211958A1Good effectReduce unwanted damageUltrasound therapyChiropractic devicesMuscle tissueConnective tissue fiber
A method and system for non-invasive treatment of a soft tissue, such as adipose tissue, muscle tissue or connective tissue. The apparatus comprises an applicator configured to apply a pressure pulse to the skin surface having a negative pressure phase with respect to ambient pressure. The method comprises applying at least one pressure pulse to the skin surface overlying the soft tissue, where the pressure pulse has at least one negative pressure phase.
Owner:SYNERON MEDICAL LTD
Methods of Preparing and Using Novel Stem Cell Compositions and Kits Comprising the Same
The present invention provides novel stem cell compositions having significant therapeutic and practical advantages, as well as methods of preparing and using such compositions for the treatment and prevention of injury and disease in patients. The invention may be applied to stem cell populations isolated from a wide variety of animals, including humans, and tissues. In particular applications, the invention is used to prepare a stem cell composition from a collagen-based tissue, such as adipose tissue, isolated from a patient, and the stem cell composition is subsequently provided to a site of actual or potential injury in the patient. The invention further includes related kits comprising the stem cell compositions, which are remarkably stable and retain viability and efficacy during storage and shipment.
Owner:VETSTEM INC
Treatment of cellulite and adipose tissue with mid-infrared radiation
InactiveUS20070142881A1Prevents inadvertent punctureNo riskDiagnosticsSurgical needlesConnective tissue fiberMid infrared
A method and apparatus that will alter the fibrous strands in the fatty layers of the skin to reduce the appearance of cellulite and adipose tissue. Electromagnetic energy is used to selectively shrink or alternatively photoacoustically ablate the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite and adipose tissue while avoiding damage to the surrounding fatty cells.
Owner:NEW STAR LASERS
Modified and stabilized gdf propeptides and uses thereof
InactiveUS20070149455A1Avoid utilizationImproved pharmacokinetic propertiesFungiBacteriaMuscle tissueAmytrophic lateral sclerosis
Modified and stabilized propeptides of Growth Differentiation Factor proteins, such as GDF-8 and Bone Morphogenetic Protein-11, are disclosed. Also disclosed are methods for making and using the modified propeptides to prevent or treat human or animal disorders in which an increase in muscle tissue would be therapeutically beneficial. Such disorders include muscle or neuromuscular disorders (such as amyotrophic lateral sclerosis, muscular dystrophy, muscle atrophy, congestive obstructive pulmonary disease, muscle wasting syndrome, sarcopenia, or cachexia), metabolic diseases or disorders (such as such as type 2 diabetes, noninsulin-dependent diabetes mellitus, hyperglycemia, or obesity), adipose tissue disorders (such as obesity), and bone degenerative diseases (such as osteoporosis).
Owner:WYETH LLC
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