60 results about "Cecum" patented technology

A temporary ostomy appliance is disclosed, including a catheter for extending through the abdominal wall into the intestine. The catheter may be a transcecal catheter for extending through the cecal valve into the ileum. A portion of a catheter that extends through the cecal valve is made collapsible when the catheter is empty. The collapsed portion expands to permit passage of effluent. A balloon carried on the catheter is preformed with a shape and size in order to permit inflation without elastic stretching of the balloon wall material. A filament is provided for permitting a portion of the catheter to be fastened to internal body tissue by surgical sutures or staples. In order to release the fastening without further surgery, the filament is withdrawn by pulling on a proximal portion outside the body.

The invention relates to a formulation for the delayed and controlled delivery of an adsorbent into the lower intestine of mammals. The formulation includes a carrageenan and an adsorbent, such as activated charcoal. The invention further relates to uses of this formulation, in particular to pharmaceutical uses. In one embodiment, the formulation is used to eliminate or reduce the side effects in the intestine, in particular in the colon, of pharmaceutical agents that are administered as a treatment for a disorder, but that have side effects when they reach the late ileum, the caecum or the colon.

The invention relates to a lactobacillus reuteri lyophilized preparation and a preparing method thereof, belonging to a microbial feedstuff preparation additive; the lactobacillus reuteri lyophilized preparation is characterized in that the weight percentage of the protectant of the lyophilized preparation is that 1 percent of sucrose, 12 percent of skimmed milk, 4 percent of lactose, 1 percent of glycerin, 2 percent of starch and the rest of water; the lactobacillus reuteri lyophilized preparation of the invention is separated by the mucous membrane of cecum of soy sauce chicken, and the lactobacillus reuteri is identified by Chinese industrial microbial culture collection management center; the bacterial strain of the invention is fermented and enlarged, and then is frozen and dried; the viable count of the freezing additive reaches 10<10>cfu/g, and can be used for feeding animals directly; the experiment of the safety of animals and the experiment of feeding the animals prove that the bacterial strain has higher safety and functionality.

The invention discloses an RPA (recombinase polymerase amplification) primer for detecting a fowl adenovirus serotype 4. The nucleotide sequence of the RPA primer is as shown in SEQ ID No.1 and SEQ ID No.2 in the description. The invention further discloses a method for detecting the RPA of the fowl adenovirus serotype 4, and the method mainly comprises the steps of primer synthesis, extraction of DNA in a sample to be tested, RPA amplification reaction and analysis of an RPA amplification product. According to the RPA primer disclosed by the invention, the specificity is strong, the sensitivity is high, and the detection result is accurate. The detection method disclosed by the invention is simple in operation and good in stability, and a low-cost, rapid and specific on-site diagnosis method for effectively detecting and authenticating chicken cecum hepatitis-hydropericardium syndrome is provided.

The invention is intended for secure emptying of organism's cavities, particularly for colon decompression. The device combine the drain with means of its delivery in the shape of everting by fluid invaginator, comprising the drain, as well as their intractor. The secure emptying of cavity is ensured by a hose with punctures, placed in drain. The liquid, feeding into hose, realizes drain's recanalization, irrigates its holes and dilutes cavity contents. Transportation of drain into colon is ensured by synergy of two intubation forces. The vanguard force is generated by fluid pressure which everts invaginator, the rearguard (extraanal)—by “cylinder-piston” unit with a cuff. The hollow unit's piston acts as pneumatic carriage, but cuff is periodically joining with invaginator with drain or intractor. Evacuaton of contents is ensured by influx-and-extract method. The sequential connection of intractor and drain ensures not only intubation, but also contents' evacuation through both ends of drain. On the drawing is represented cecum with a distal fragment of drain-irrigation system of device: at left—in “evacuation” mode, at right—in “drain's recanalizaton-irrigation”, “intestines irrigation” mode.

Preparations for preventing bile acid diarrhea characterized by containing a bile acid adsorbent coated with a polymer so as to allow the release thereof around the lower part of the small intestine and the cecum; and medicines (for example, antilipemics) comprising a combination of bile acid re-absorption inhibitors with the above-described preparations for preventing bile acid diarrhea.

The invention discloses a double-balloon intestine fistulization catheter for preventing anastomotic fistula after a colorectal surgery. The double-balloon intestine fistulization catheter comprises a catheter body, a first balloon, a second balloon, a threaded compressed tablet, a first water injection opening and a second water injection opening, wherein the first balloon and the second balloon are two hollow balloons which sleeve the catheter body and are made of an elastic material; the first balloon is close to the head end; the threaded compressed tablet sleeves the part between the second balloon and the tail end; a side hole is formed in the wall, between the first balloon and the head end, of the catheter body; the first water injection opening and the second water injection opening are positioned at the tail end of the catheter body, and are respectively communicated with the first balloon and the second balloon. According to the invention, when the catheter is inserted into the intestinal tract after an intestinal surgery, the circulation of the small intestine is blocked after the first balloon is injected with water to enable intestinal fluid to be led out of the body through the head end and side hole of the catheter; after being injected with water, the second balloon and the threaded compressed tablet positioned outside the body are coordinated to fix the catheter to prevent slipping or shifting of the catheter, and at the same time, the intestinal wall of the cecum is clung to and adhered with the abdominal wall to prevent intestinal fluid from leaking outwards to the abdominal cavity.

The invention relates to the field of biological analysis methods, and in particular to an analysis method of cecal metabolome in a broiler chicken. The change of metabolites and metabolic pathways ofcecal contents after the broiler chicken eats a yeast culture produced at different fermentation time is detected by jointly using a gas chromatography-mass spectrometry, thereby determining the influence of the yeast culture on the cecal metabolic regulation and the metabolites of the broiler chicken. Metabolomics data show that yeast culture is used for feeding the broiler chicken, the cecal differential metabolites mainly involve in amino acid metabolism and cholesterol metabolism, and participates in fat, vitamin digestion and absorption processes.

The invention provides a preparation method of a mice intestinal flora alteration ERIC-PCR (Enterobacterial Repetitive Intergenic Consensus sequence-based Polymerase Chain Reaction) fingerprint spectrum. The preparation method comprises the steps: moulding mice intestinal flora alteration caused by antibacterial-associated diarrhea, extracting a cecum content DNA, eliminating humic acid in the cecum content DNA, eliminating a PCR inhibitor in the cecum content DNA, performing ERIC-PCR amplification and native polyacrylamide gel electrophoresis (Native-PAGE), and comparing with a conventional flora analysis result so as to establish the ERIC-PCR fingerprint spectrum of the mice intestinal flora alteration. According to the preparation method, with a pure-series mice as a research object, the defect caused when a conventional bacterium culturing method is applied to the microflora analysis is solved. The preparation method can be used for rapid detection of the laboratory mice intestinal flora alteration, prevents the defects of complicated operation, long time consumption, large workload and the like of conventional bacterium separation and culturing, and is capable of accurately, rapidly and effectively detecting the mice intestinal flora distribution condition.

The invention relates to a lactobacillus plantarum RS-09 with high adhesion and applications thereof, and belongs to the field of microorganisms. The strain is separated from apple juice, and is preserved in in the China General Microbiological Culture Collection Center with a preservation number of CGMCC NO.17118; has stronger acid resistance and choline salt resistance, can be stored for a longtime, has higher adhesion capacity to human colon cancer cells HT-29, and can be stably planted in intestinal tracts, wherein the planting rate of the cecum is highest; can obviously reduce the content of TNF-alpha in serum, increase the content of IL-10 and IL-4 in the serum, and has the function of immunoregulation; and has strong bacteriostatic effect on salmonella enteritis, has prevention andtreatment effects on enteritis diseases caused by flora disorder, can be applied to the field of functional foods, not only has practical production value, but also has very important significance onbody health.

Provided herein are compositions, systems, and methods for treating a disease, such as kidney and/or cardiovascular disease, with an agent that reduces the production of trimethylamine (TMA) or trimethylamine-n-oxide (TMAO) in a subject. In certain embodiments, the agent is: i) 3,3-dimethyl-1-butanol (DMB) or a DMB derivative or related compound, ii) acetylsalicylic acid or derivative thereof (e.g., with an enteric coating for delivery to the colon and/or cecum); iii) a flavin monooxygenase 3 (FMO3) inhibitor; iv) a gut TMA lyase inhibitor; v) an antibiotic or antimicrobial; vi) a probiotic or prebiotic; vii) an antiplatelet agent; or viii) a TMA and/or TMAO sequestering agent.

This invention relates to new methods of treating parasitic infections, such as trichomonas vaginalis infection and cecum amoeba infection, using L-enantiomer enriched ornidazole, in particular enantiomerically pure L-ornidazole, which provides benefits such as higher efficacy and lower toxicity to central nervous system over the existing racemic Ornidazole drug. New methods of synthesizing L- and D-enantiomers of Ornidazole in high purity and enantiomeric excess (ee), new formulations of the enantiomerically enriched L- or D-ornidazole, as well as their preparation processes and methods of use, are also disclosed.

The invention relates to a method for establishing a model of fluorescence orthotopic transplantation of subcutaneous metastasis organ cancers, which is characterized in that human colon adenocarcinoma cell strains or cancer cell strain green fluorescent proteins (GFP) of corresponding organs are selected; GFP plasmids carry out transfection on cancer cell strains of the organs via retrovirus pLPCX so that the cancer cell strains of the organs contain GFP expression plasmids; a GFP gene is connected with a pLPCX vector via a T4 ligase; a GFP-pLPCX vector is transfected to a PT67 package cell to obtain a Lovo cell; nude mice are selected and subjected to subcutaneous inoculation with Lovo cell suspension; tumors can be formed in about 4 weeks; orthotopic transplantation is carried out after green fluorescence is observed; a cut is opened on the skin and peritoneum; about 1cm cecum of the nude mice is taken out of the peritoneum; the gap between the cecum and the peritoneum is sutured and the cecum is transferred subcutaneously; the cut cecum is subjected to serosa; two fluorescence-carrying tumors with diameter of about 1mm are transplanted to the cecum via the suture and the skin is closed.

The invention discloses an escherichia coli CG1061 strain for effectively degrading aflatoxin B1. The strain is collected in the Guangdong microbial culture collection center on February 1, 2018, withthe collection number being GDMCC NO:60324. The strain is separated from a chicken cecum, is a nonpathogenic escherichia coli, can effectively degrade AFB1, can be applied to detoxicating microbes, detoxicating enzymic preparations and the like for preparing aflatoxin B1, and has a good application prospect in the fields of food and feed processing and the like.

The invention discloses a gradient centrifugation separation method of total microbes in porcine gastrointestinal contents and manure. The gradient centrifugation separation method comprises the following steps: A, performing reagent preparation of a separation buffer solution; B, performing an experimental method as follows: (1) selecting the porcine gastrointestinal contents and manure and aseptically collecting contents and manure in stomach, jejunum, ileum, cecum and colon; (2) respectively weighing the weight of the contents and manure, placing into a sterile centrifugal tube, centrifuging and discarding supernatant; (3) adding the separation buffer solution into the centrifugal tube, shaking up on a vortex mixer and centrifuging; (4) taking out the centrifugal tube, pouring supernatant fluid into the centrifugal tube, centrifuging the centrifugal tube loaded with the supernatant fluid and discarding the supernatant; (5) weighing the separation buffer solution, adding into a centrifugal tube a, shaking up on the vortex mixer, centrifuging and discarding the supernatant; (6) respectively repeating the step 3, the step 4 and the step 5 twice; (7) pouring away the supernatant fluid, transferring thalli into a 2ml centrifugal tube and preserving at the temperature of -70 DEG C for determining the dry weight of the thalli and a microbial flora. The method is easy, simple and convenient to operate and the cost is low.