45 results about "Controlled delivery" patented technology

Systems and methods for assembling and introducing cartridges containing remediating component(s) into packaged beverages are provided herein. In particular, a transport system for transporting sealed cartridges to an introduction system for delivery into beverage containers is provided herein. The transport system may receive cartridges from the source, via an inlet, into a straight-line tube having a diameter approximately 1.1 times a width of the cartridges. A transition guide fluidly connects the straight-line tube to the introduction system and may include an outlet opening through which cartridges are dispensed. The transport system includes assist jets configured to inject inert gas into the straight-line tube to propel cartridges, pressure sensors disposed along the transport tube to detect cartridge presence or movement, and a control system operably coupled to the pressure sensors and assist jets to modulate gas injection and control delivery of the cartridges to the introduction system.

The utility model discloses a biological prevention and control releasing device based on a four-axis unmanned aerial vehicle, which belongs to the technical field of biological prevention and control and comprises an unmanned aerial vehicle body. The throwing mechanism comprises a connecting assembly and a storage shell, the top of the connecting assembly is fixedly connected to the bottom of the unmanned aerial vehicle body, the bottom of the connecting assembly is clamped to the two sides of the top of the storage shell in a limiting mode, the storage shell comprises a storage bin, a protection cover is connected to the bottom of the storage bin, and a discharging bottom cylinder is connected to the bottom of the protection cover; a discharging buffer pipe is arranged among the storage bin, the protection cover and the discharging bottom cylinder in a communicating mode. And a synchronous putting assembly is arranged in the storage shell and comprises a material shifting rod and a discharging ratchet wheel, the material shifting rod and the discharging ratchet wheel are arranged at the two ends of the discharging temporary storage pipe in a transmission mode correspondingly, and the synchronous putting assembly is used for stably putting trichogramma eggs, so that the situation that the trichogramma eggs are put too much or too little on one side is avoided.

An autoinjector comprising a housing and a syringe assembly that carries a needle. A drive spring 8 is configured to urge a driver 10 to rotate, which controls delivery of a drug. Biasing means are

The invention discloses a negative pressure sealing drainage device, and relates to the technical field of medical instruments, and the negative pressure sealing drainage device comprises an arm band assembly, a liquid storage assembly, a dressing assembly and a drug delivery assembly. The arm band assembly comprises an arm band, elastic binding bands, a control panel, a display screen and a storage battery, and the elastic binding bands are fixed to the upper end and the lower end of the arm band through hook-and-loop fasteners. The liquid storage assembly comprises a liquid storage box, a negative pressure pipe, an overflow floater and a negative pressure pump. The dressing assembly comprises a dressing bottom layer, an annular airbag ring, a polyimide substrate layer, a sensor and a top covering layer, the annular airbag ring is arranged at the bottom of the dressing bottom layer, and the sensor is arranged at the top of the polyimide substrate layer. The medicine delivery assembly comprises three medicine cavities, a conveying pipe, a micro peristaltic pump and a mixing pipe. And the end part of the negative pressure tube penetrates through each layer of the dressing to a wound position. The device is good in sealing effect, capable of monitoring the wound state in real time, capable of achieving independent control delivery of various drugs and convenient to carry.

The present invention relates to pro-molecules having a mono-, oligo-, or polysaccharide as a carrier, which allow the controlled delivery of their active ingredients, to the method for obtaining the pro-molecules and to uses thereof. The present invention has applications in the field of chemistry, especially in fragrances, flavors (edible), pharmaceuticals, dietary supplements, and agricultural actives (pesticides and fertilizers, inter alia).

The exemplary embodiments attempt to identify impending hypoglycemia and / or hyperglycemia and take measures to prevent the hypoglycemia or hyperglycemia. Exemplary embodiments may provide a drug delivery system for delivering insulin and glucagon as needed by a user of the drug delivery system. The drug delivery system may deploy a control system that controls the automated delivery of insulin and glucagon to a patient by the drug delivery system. The control system seeks among other goals to avoid the user experiencing hypoglycemia or hyperglycemia. The control system may employ a clinical decision support algorithm as is described below to control delivery of insulin and glucagon to reduce the risk of hypoglycemia or hyperglycemia and to provide alerts to the user when needed. The control system assesses whether the drug delivery system can respond enough to avoid hypoglycemia or hyperglycemia and generates alerts when manual action is needed to avoid hypoglycemia or hyperglycemia.

1. The name of the design product: discharging machine (1502). 2. The use of the design product: controlled delivery of materials. 3. The design features of the design product: in shape. 4. The picture or photo that best indicates the design features: perspective view 1.

The invention relates to a transdermal patch combined with an electronic control system in the form of a smartwatch. The patch features a display that shows information about the current status and drug delivery. Simultaneously, electrical contacts within the patch enable the targeted delivery of active ingredients under the skin. The system reacts in real time to the patient's condition and can be used for various applications including insulin control, blood measurement and vacuum blood tests. The invention offers precise and needs-based control of drug delivery and enables continuous monitoring and adjustment based on the patient's current needs.

The present invention relates to a polymer system with a nano-in-micro architecture (fucoidan micromatrix with PLGA nanoparticles incorporated therein) and finds application as a system for controlled delivery of low molecular weight water-soluble medicinal substances (e.g. galantamine hydrobromide, benzydamine hydrochloride, betahistine hydrochloride, etc.). The system includes polylactic-coglycolic acid (PLGA) nanoparticles in a fucoidan matrix, with the PLGA content being from 1% to 10% and fucoidan content being from 90% to 99% in the form of a fucoidan matrix with 100% PLGA nanoparticles incorporated therein, with the microparticles having an average diameter of 2 μm to 10 μm. The polymer system for controlled release of low molecular weight water-soluble drugs, when loaded with low molecular weight water soluble drugs such as galantamine, benzydamine, doxylamine, contains polylactic-co-glycolic acid from 1% to 10% and fucoidan from 90% to 99% in the form of a fucoidan matrix with PLGA nanoparticles incorporated therein, in the form of a fucoidan matrix with PLGA nanoparticles incorporated therein from 94% to 99% and a low molecular weight water-soluble drug from 1% to 6%, wherein the microparticles have an average diameter of 2 μm to 10 μm.

The disclosure pertains to implantable medical devices for controlled delivery of therapeutic agents. Some devices according to the disclosure have a titanium reservoir, and a porous titanium oxide based membrane to control the rate of release of the therapeutic agent. The reservoir contains a formulation of the active agent, including a stabilizer for the active agent, wherein the stabilizer is provided in an extended-release configuration or a sustained release carrier.

An application nozzle for applying dental active substances in the oral cavity of a patient comprises a nozzle body extending flat in a longitudinal direction from a connection region towards a free treatment end. The nozzle body tapers in cross-section towards the treatment end and integrates at least two media channels extending independently from the connection region to the free treatment end. The nozzle enables controlled delivery of multiple dental active substances simultaneously through separate channels while maintaining precise application geometry. The tapered design facilitates access to confined oral cavity areas and enhances treatment effectiveness. An active substance applicator incorporating such application nozzle provides improved dental treatment delivery compared to conventional single-channel applicators.

Apparatus, systems, and methods for controlled delivery of electrolytes and cell permeation therapy to tissue sites are disclosed. The systems, apparatus, and methods may include designs having features for efficiently deploying a flexible substrate with electrodes at the tissue site for treatment and for facilitating the retraction of the electrodes back into a housing for removal after treatment. The systems, apparatus, and methods may further include expansion members for radially expanding the flexible substrate to aid in positioning the electrodes adjacent to tissue to facilitate treatment.

The present application relates to the technical field of water pollution treatment, and discloses a river and lake water treatment microbial carrier delivery device and a use method, which comprises a delivery ship body, a delivery storage box and a delivery mechanism, and the delivery mechanism is composed of three components, i.e., a quantitative delivery component, a depth delivery component and a regulation and control delivery component. The delivery depth is adjusted through an extension pipe, the multi-pipe differential angle regulation and control is realized through a crankshaft and a regulation and control frame structure, and the closed-loop quantitative delivery is realized through a piston structure and a one-way valve. The present application solves the technical problem that the existing microbial delivery device can only be used for surface spraying, the vertical microbial distribution in the water body is uneven, and the treatment blind area is prone to occur. The present application can dynamically adjust the delivery parameters, realize the full-water-depth and multi-point three-dimensional uniform delivery of the river and lake water body, greatly improve the treatment effect and the utilization rate of the microbial agent, adapt to different river and lake scenes, and is stable and reliable in operation, and is suitable for river and lake sewage treatment and ecological restoration engineering.

The present invention describes methods, systems, and apparatuses for controlled delivery of wellbore fluids such as providing a plurality of pressurized sources of an aqueous base fluid having respective flow rates, and target predetermined physical and / or chemical characteristic values; blending at least two of the pressurized sources of aqueous base fluid thereby creating a blended pressurized source of aqueous base fluid; testing to determine the blended source's physical and / or chemical characteristics; comparing to the target predetermined physical and / or chemical characteristic values to identify if they match; based on the comparison altering the flow rates of at least one of the plurality of pressurized sources of aqueous base fluids; and repeating steps until the blended pressurized source of aqueous base fluid matches the target predetermined physical and / or chemical characteristics.

The devices, systems, and methods disclosed herein may be directed to a delivery system including a therapeutic member configured for endoluminal placement via the delivery system into the esophagus of the patient, wherein the therapeutic member comprises a treatment portion comprising a film for controlled release of a chemotherapeutic agent. The film may comprise a control region, a therapeutic region, and a substantially impermeable base region. The film is configured to release the chemotherapeutic agent in a direction away from the substantially impermeable base region. The delivery system is configured to enable a treatment provider to position the treatment portion of the therapeutic member proximate to a treatment site associated with the esophagus of the patient, and the therapeutic member is configured to administer a therapeutically effective dose to the treatment site for a sustained period following endoluminal placement of the therapeutic member.

Disclosed herein are exemplary medical devices for controlled delivery of material compositions, particularly occlusive, therapeutic, or diagnostic compositions.

The present application relates to the technical field of medical data transaction, in particular to a cross-chain medical data transaction method, a transmission protocol and a system, comprising compliance preprocessing and quality characterization of medical data to form a transaction data offer; and registering the transaction data offer as an on-chain queryable offer record, outputting an offer fingerprint and an offer constraint set; initiating a transaction request and giving a use commitment and a compliance qualification declaration; a cross-chain coordination mechanism performs consistency verification, generates a cross-chain authorization credential, and outputs an authorization status record; a data provider executes controlled delivery according to the cross-chain authorization credential and the authorization status record, and generates a use audit event stream; when a revocation condition, out-of-range access or regulatory audit request is triggered, the cross-chain coordination mechanism executes freezing, revocation or accountability treatment according to the authorization status record and the use audit event stream, and completes the closed loop of the transaction. The present application improves the data credibility, controllability and automatic matching ability under multi-chain collaboration.

Rotary microfluidic medical pump and pumping method embodiments are discussed herein that may include elements having an integrated set for establishing fluid communication with a patient's body. Such embodiments may be used for controlled delivery of small and precise volumes of therapeutic or non-therapeutic medical fluids to a patient in a variety of environmental conditions.

The invention relates to administration of clinical anesthesia. Particular embodiments provide systems and methods for controlled delivery of a combination of an analgesic agent and a hypnotic agent. More specifically, the invention relates to closed-loop control systems / methods for automatically controlling the administration of a combination of a hypnotic agent and an analgesic agent in a clinical anesthesia setting which incorporate feedback based on one or more indirect measures / indicia of analgesia. The invention further relates to such control systems / methods that account for limitations of such indirect measures / indicia of analgesia.

A customizable drug delivery system and method utilizing a laser pattern generator (LPG) to define application of a drug delivery payload (DDP) contained within a drug delivery device (DDD) to a drug delivery target (DDT) is disclosed. A computer control device (CCD) supervises the LPG to select a drug payload pathway (DPP) from a drug pathway database (DPD) and writes the selected DPP to the DDD. This pathway patterning process (PPP) modifies the hydrophilic properties of the DDD and enables the DDD to selectively attract and absorb the DDP. The DDD is then injected with the DDP or exposed for drug exposure time (DET) by the CCD and DPD during which the DPP written to the DDD absorbs a controlled amount of DDP. The DDD when subsequently inserted into a drug delivery target (DDT) delivers the DDP to the DDT under controlled delivery rates defined by the DPP and the DET.

A system for administration of medicament to a user-body, the system comprising an automated medicament delivery device configured to deliver medicament to a user utilizing an AID algorithm using a set of initial input parameter values, receive a user input selecting at least one desired therapy parameter value, receive an additional user input enabling optional adjustments to input parameter values of an AID algorithm at least partially controlling delivery of the medicament, adjust one or more input parameters values of the set of initial input parameter values of the AID algorithm to create a set of adjusted input parameter values, generate a request to adjust administration of medicament to a user via the automated medicament delivery device utilizing at least a portion of the AID algorithm using the set of adjusted input parameter values, and deliver medicament to the user according the generated request.

A treatment delivery system includes a fluid delivery system connected to a first fluid reservoir and a second fluid reservoir. The system directs a first fluid from the first fluid reservoir to a treatment site and directs a second fluid from the second fluid reservoir to the treatment site and a control unit to control the fluid delivery system according to a treatment process comprising a flow of the first fluid and the second fluid, the treatment process including multiple phases. A first phase includes a controlled delivery of the first fluid from the first fluid reservoir to the treatment site. A second phase of the plurality of phases includes a controlled delivery of the second fluid from the second fluid reservoir to the treatment site, the control unit automatically activating a transition from at least the first phase to the second phase.

Described are devices, systems, and methods for controlled delivery of therapeutic and / or diagnostic agent(s) in a tissue in a subject. In particular, provided are carrier devices in which the agent(s) may be enclosed. One or more carrier devices may be injected or implanted at target loci in a tissue, such as in a malignant neoplasm. The agent(s) may diffuse from the carrier devices in a predetermined and controlled manner. Further provided are methods for developing optimized parameters for intraparenchymal placement of carrier devices and diffusion of the agent(s), to achieve an optimized therapeutic exposure in the target tissue. Further provided are devices and systems for intraparenchymally placing carrier devices at desired loci in a tissue.

A method for the controlled delivery of a fracturing fluid to a well bore comprises formulating an aqueous base fluid such that it meets or exhibits desired physical and chemical characteristics for an optimal fracturing fluid. The formulation of the aqueous base fluid max involve commingling one or more sources of waste water with a source of fresh water followed by controlled injection of one or more additives. This process is substantially completed prior to delivering the aqueous base fluid to the well site. This allows the delivery of an optimal volume of the aqueous base fluid with homogeneously blended additives to the well bore.

A portable and self-contained oilfield tool cleaning apparatus is disclosed for on-site cleaning of oilfield tools within an enclosed cleaning vessel. The apparatus supports multiple cleaning techniques, including chemical, hydro, mechanical, thermal, and optional ultrasonic cleaning, through controlled delivery of water, chemical agents, heated fluids, steam, and air. The system includes a fluid-delivery subsystem having a freshwater tank, a monitoring and control subsystem, a fluid-recovery and waste-collection subsystem, and an optional hydro-vacuum system configured to assist in debris removal, slurry evacuation, and spent fluid recovery. An internal spray system applies cleaning media uniformly to the oilfield tool, while a removable carrier and secondary containment structure enhance operational flexibility and environmental protection. The apparatus is transportable, modular, and designed for operation in harsh field environments, enabling efficient, safe, and environmentally responsible cleaning of oilfield tools while minimizing downtime and environmental risk.

Disclosed is a drug delivery system that specifically carries and releases an active substance to a target organ or tissue. The coating of the shape memory component constituting the drug delivery system enhances the biocompatibility and controlled delivery of the active substance previously loaded into the coating material to the target organ or tissue.

Systems and methods for assembling and introducing cartridges containing remediating component(s) into packaged beverages are provided herein. In particular, a transport system for transporting sealed cartridges to an introduction system for delivery into beverage containers is provided herein. The transport system may receive cartridges from the source, via an inlet, into a straight-line tube having a diameter approximately 1.1 times a width of the cartridges. A transition guide fluidly connects the straight-line tube to the introduction system and may include an outlet opening through which cartridges are dispensed. The transport system includes assist jets configured to inject inert gas into the straight-line tube to propel cartridges, pressure sensors disposed along the transport tube to detect cartridge presence or movement, and a control system operably coupled to the pressure sensors and assist jets to modulate gas injection and control delivery of the cartridges to the introduction system.

An oral drug delivery device for the controlled delivery of a lipophilic drug, the device comprising a lipophilic drug emulsified in a film-forming hydrophilic polymer, a release modifier, and an emulsifier, the device being incorporated into or formed as an orally administrable unit dosage form, wherein upon ingestion of the unit dosage form and contact with the gastric and / or intestinal media, the release modifier forms a viscous gel that gradually erodes as it travels through the stomach and intestinal tract, releasing the emulsified drug into the surrounding environment at a controlled rate.

The utility model discloses a kitchen storage cabinet with refrigeration function in the technical field of storage cabinets, which comprises a base, a cabinet body and a shunting pipeline, the cabinet body is fixedly connected to the top of the base, the shunting pipeline is fixedly connected to the rear side wall of the cabinet body, the left side wall and the right side wall of the inner cavity of the cabinet body are fixedly connected with division bars, and the division bars are fixedly connected to the left side wall and the right side wall of the inner cavity of the cabinet body. The partition strips are sequentially arranged from top to bottom, a storage basket is placed between the partition strips, a sealing frame is placed between the partition strips and located on the lower side of the storage basket, a partition plate is fixedly connected to the interior of the sealing frame, through holes are formed in the bottom of the partition plate, and the through holes are evenly distributed. According to the storage cabinet with the refrigeration function for the kitchen, partition refrigeration can be conducted on the storage cabinet, the practicability of the storage cabinet is improved, cold air flow can be controlled and conveyed according to different adjusted storage cabinet spaces, and the refrigeration effect is improved.

This application relates to a platform for providing compounds and implants that provide long-lasting release of therapeutics, such as statins and steroids, in biological and therapeutic applications, such as in ocular administration and / or via implantation or insertion. In some embodiments, the compounds of the application comprise a first radical (D1) and a second radical (D2) (e.g., having the formula: D1-L-D2). In certain instances, D1 is a processable group such as a radical of a steroid, L is a linker, and D2 is a drug such as a statin. While there are some controlled delivery systems for delivering an active pharmaceutical ingredient (API) to a treatment site, the systems generally contain polymer carriers that can create technical and / or regulatory challenges, such as, for example, burst release kinetics, low drug loading, and adverse inflammatory responses. The present application presents a therapeutic consisting entirely or almost entirely of API which could address such technical and regulatory challenges.