108 results about "Controlled delivery" patented technology

A medical device for treating a cancerous tumor comprises an electric field generating circuit configured to generate one or more electric fields at or near a site of the cancerous tumor. The cancerous tumor comprises a cancerous cell population. The medical device comprises control circuitry in communication with the electric field generating circuit. The control circuitry is configured to control delivery of the one or more electric fields from the electric field generating circuit at or near the site of the cancerous tumor. The medical device comprises one or more electrical leads in electrical communication with the electric field generating circuit. The medical device further comprises a drug delivery catheter for delivery of one or more chemotherapeutic agents. The control circuitry causes the electric field generating circuit to generate one or more electric fields at frequencies selected from a range of between 10 kHz to 1 MHz at the site of a cancerous tumor located within a bodily tissue. The one or more electric fields are effective to delay mitosis and cause mitotic synchronization within a proportion of the cancerous cell population.

Methods, devices, and systems are disclosed for controlled delivery of a therapy, such as a stimulant, to a mouth of a subject via an oral device positioned in a secured configuration in the mouth. At least one of a tongue position stimulator (TST) and tongue position sensor (TSE) is provided, according to certain aspects. According to another aspect, a stimulus is delivered to the mouth and / or tongue via a mouthpiece secured to the subject's teeth. In another regard, a stimulus is delivered that generates a natural response to eliminate or reduce sleep disorders, such as for example at least one of snoring and obstructive sleep apnea.

Systems and methods for assembling and introducing cartridges containing remediating component(s) into packaged beverages are provided herein. In particular, a transport system for transporting sealed cartridges to an introduction system for delivery into beverage containers is provided herein. The transport system may receive cartridges from the source, via an inlet, into a straight-line tube having a diameter approximately 1.1 times a width of the cartridges. A transition guide fluidly connects the straight-line tube to the introduction system and may include an outlet opening through which cartridges are dispensed. The transport system includes assist jets configured to inject inert gas into the straight-line tube to propel cartridges, pressure sensors disposed along the transport tube to detect cartridge presence or movement, and a control system operably coupled to the pressure sensors and assist jets to modulate gas injection and control delivery of the cartridges to the introduction system.

Example apparatuses and systems are disclosed for providing controlled delivery of electrolysis products to a site which may be used for treatment of infection and ablation of undesirable cells and tissue. A system disclosed may include a power supply, two electrodes, an aqueous matrix that may close the electric circuit between the electrodes at the treated site, and a controller. The controller may control the electrical circuit to induce a direct current through the electrodes and an aqueous matrix to produce electrolysis products. The duration and magnitude of the charge applied may determine the dose of the products applied to the treatment site. The composition of the electrodes and the aqueous matrix may be chosen to produce desired products. An apparatus is disclosed that may be in the form of a pad for applying to a wound. An apparatus is disclosed that may be used for treating internal tissue.

The present disclosure provides compounds comprising at least one GalNAc moiety. The compounds may further comprise or be a therapeutic moiety and / or compound. The compounds thus provide a means of controlled delivery of therapeutic moieties to biological targets by incorporation of the GalNAc moiety. The present disclosure also provides synthetic precursors to the compounds. The present disclosure further provides pharmaceutical compositions and kits comprising the compounds, methods of inhibiting expression of a target nucleic acid, and methods of treating or preventing a disease or disorder by administering to a subject in need thereof the compounds or pharmaceutical compositions.

Disclosed herein are exemplary medical devices for controlled delivery of material compositions, particularly occlusive, therapeutic, or diagnostic compositions. Medical devices disclosed herein comprise components for maintaining a stationary position, for providing catheters at a precise step in a method, for inflating or deflating a balloon, if present, and for providing a composition to a target site.

A device for delivering a medical fluid (4) comprising a body which houses: at least one containment tank (20) of a medical fluid, a fluid injection device (24) which interfaces with said containment tank (20) and is suitable to allow controlled delivery of a fluid through a cannula (32), an extraction device (40) of the cannula (32) from a retracted or rest configuration to an extracted or infusion configuration, activation means (44) which comprise a rotor (48), rotatable about a rotation axis (X-X) in an injection rotation direction (I) and in a control rotation direction (C), opposite each other.

The utility model discloses a biological prevention and control releasing device based on a four-axis unmanned aerial vehicle, which belongs to the technical field of biological prevention and control and comprises an unmanned aerial vehicle body. The throwing mechanism comprises a connecting assembly and a storage shell, the top of the connecting assembly is fixedly connected to the bottom of the unmanned aerial vehicle body, the bottom of the connecting assembly is clamped to the two sides of the top of the storage shell in a limiting mode, the storage shell comprises a storage bin, a protection cover is connected to the bottom of the storage bin, and a discharging bottom cylinder is connected to the bottom of the protection cover; a discharging buffer pipe is arranged among the storage bin, the protection cover and the discharging bottom cylinder in a communicating mode. And a synchronous putting assembly is arranged in the storage shell and comprises a material shifting rod and a discharging ratchet wheel, the material shifting rod and the discharging ratchet wheel are arranged at the two ends of the discharging temporary storage pipe in a transmission mode correspondingly, and the synchronous putting assembly is used for stably putting trichogramma eggs, so that the situation that the trichogramma eggs are put too much or too little on one side is avoided.

An autoinjector comprising a housing and a syringe assembly that carries a needle. A drive spring 8 is configured to urge a driver 10 to rotate, which controls delivery of a drug. Biasing means are

The invention discloses a negative pressure sealing drainage device, and relates to the technical field of medical instruments, and the negative pressure sealing drainage device comprises an arm band assembly, a liquid storage assembly, a dressing assembly and a drug delivery assembly. The arm band assembly comprises an arm band, elastic binding bands, a control panel, a display screen and a storage battery, and the elastic binding bands are fixed to the upper end and the lower end of the arm band through hook-and-loop fasteners. The liquid storage assembly comprises a liquid storage box, a negative pressure pipe, an overflow floater and a negative pressure pump. The dressing assembly comprises a dressing bottom layer, an annular airbag ring, a polyimide substrate layer, a sensor and a top covering layer, the annular airbag ring is arranged at the bottom of the dressing bottom layer, and the sensor is arranged at the top of the polyimide substrate layer. The medicine delivery assembly comprises three medicine cavities, a conveying pipe, a micro peristaltic pump and a mixing pipe. And the end part of the negative pressure tube penetrates through each layer of the dressing to a wound position. The device is good in sealing effect, capable of monitoring the wound state in real time, capable of achieving independent control delivery of various drugs and convenient to carry.

The present disclosure relates to devices and systems for targeted and controlled delivery of a therapeutic agent to a treatment site of an eye. Particularly, aspects are directed to a therapeutic agent delivery device that includes a polymeric substrate having a release region, a delivery region, and a receiving region; one or more reservoirs formed within the release region; a therapeutic agent disposed within the one or more reservoirs; an active, passive, or combination thereof controlled release mechanism for release of the therapeutic agent from the one or more reservoirs into the delivery region; and a circuit formed on the polymeric substrate, the circuit having a current source, a first iontophoresis electrode located within the delivery region for transport of the therapeutic agent from the delivery region into a target tissue via electromigration, and a second iontophoresis electrode located within the receiving region for maintaining electroneutrality within the tissue.

A valve assembly for a medical device includes a body having an inlet in fluid communication with a fluid source and an outlet in fluid communication with a delivery conduit of the medical device. The valve assembly includes a shuttle configured to move within the body between first and second positions to control delivery of fluid from the inlet to the outlet. In the first position, the shuttle is configured to maintain the fluid at a first pressure within the body and block the outlet from the inlet such that the delivery conduit is isolated from the fluid at the first pressure. In the second position, the shuttle is configured to maintain the fluid at a second pressure within the body and fluidly couple the outlet to the inlet such that the delivery conduit receives the fluid at the second pressure.

A drug delivery device comprising a reservoir containing a fluid to be delivered from the device by advancing a piston in the reservoir at an advancement speed that defines a delivery rate for a medicament. An electric motor drives a delivery mechanism of the drug delivery device by rotating so as to advance the piston at the advancement speed. A control unit is configured to control the rotational speed and on / off state of the electric motor. The rotational speed of the electric motor is measured by operating the electric motor in a monitoring mode for detecting a back electromagnetic force signal, and the signal is sent to the control unit. The control unit controls the rotational speed of the electric motor so that the back electromotive force signal can be detected in the monitoring mode. In addition, the control unit adjusts the on / off state of the electric motor to control the delivery rate of the medicament through the outlet.