647results about "Contracting/expanding measuring chambers" patented technology

A delivery device includes a durable housing portion and a separable disposable portion that selectively engage and disengage from each other. The disposable housing portion secures to the patient-user and may be disposed of after it has been in use for a prescribed period. Components that normally come into contact with a patient-user or with an infusion medium, including a pump device, are supported by the disposable housing portion for disposal after the prescribed use, while the durable housing portion supports other components such as electronics for controlling delivery of the infusion medium from the reservoir and a drive device and drive linkage.

A system for the metering and delivery of small discrete volumes of liquid is comprised of a small or minimal number of inexpensive components. One such component is a movable member, such as a miniature precision reciprocating displacement pump head, which is driven by an actuator that comprises a shape memory alloy material. The operating mechanism of the system is of little or minimal complexity. The system facilitates the precise metering and delivery of the small discrete volumes of liquid. Potential applications for the system include subcutaneous, long-term, automated drug delivery, for example, the delivery of insulin to a person with diabetes. In such an application, the small, simple and inexpensive nature of the invention would allow for its use as both a portable and a disposable system.

A dispenser for dispensing a substance, such as a pharmaceutical, ophthalmic, dermatological, cosmeceutical, cosmetic or other product, has a body defining a variable-volume storage chamber for storing the product. A dispensing portion of the dispenser is connected with the body and defines a bore coupled in fluid communication with the storage chamber for receiving substance therefrom, and an outlet aperture coupled in fluid communication with the bore. A one-way valve of the dispenser includes an axially-extending valve seat and an axially-extending flexible valve cover seated on the valve seat and defining a normally-closed, axially-extending seam therebetween forming a fluid-tight seal between the valve cover and valve seat. The flexible valve cover is movable relative to the valve seat and the seam is connectable in fluid communication with the outlet aperture to allow the passage of substance through the seam and out of the dispenser. The dispenser further comprises an actuator and piston assembly including a piston receivable within the bore, a manually-engageable actuator connected to the piston for moving the piston between first and second positions relative to the bore to dispense substance within the bore through the outlet aperture, and an integral, dome-shaped spring coupled to at least one of the piston and the actuator for biasing the piston in a direction from one of the first and second positions toward the other.

A fluid dispensing system provides a non-contact method of monitoring the change in the fluid volume over time. This approach avoids the use of probes or sensors that come into direct contact with the fluid to be dispensed. The system comprises an apparatus comprising three chambers. The first chamber has a fixed volume and contains a pressurized gas. A solenoid valve is used to control the flow of gas from the first chamber into the second. The second chamber is sealed so that the combined mass of air in the first and second chambers remains fixed. The third chamber is adjacent to the second and contains medication in the form of incompressible fluid that is to be administered to a human or animal subject via a suitable delivery port. A piston is disposed between the second and third chambers and is movable responsive to the flow of gas into the second chamber to dispense fluid from the third chamber as desired. By sensing the pressure in the first and second chambers at any point in time, a processor is programmed to calculate the flow rate or dispensed volume of the fluid being delivered using principles derived from the Ideal Gas Law.

A volume adjustable manual pipette having a hand-holdable housing supporting (i) an electronic digital display and associated position sensing and control circuitry, (ii) a plunger unit and (iii) a quick set volume adjustment mechanism for simultaneously controlling the volume setting of the pipette and the electronic display, the quick set volume adjustment mechanism comprising a pipette volume setting member for limiting upward movement of the plunger unit within the housing to define the volume setting for the pipette and the volume setting member being supported for axial movement on the plunger unit and releasably secured relative to the housing by a pipette user operable locking mechanism. When released from the housing, the volume setting member is axially moveable on and with the plunger unit to quickly set the volume for the pipette. When secured to the housing, the plunger unit is axially moveable relative to the volume setting unit to aspirate and dispense the selected volume of liquid into and from a pipette tip extending from a lower end of the housing. The volume setting of the pipette is monitored by the sensing and control circuitry to provide a real time display of the volume setting of the pipette.

The invention relates to a method for dosing a volume of liquid (VF) of less than 1 !l that is to be dispensed, by means of a dosing pump, in particular a pipette (2). According to said method, a tip (13) is completely filled with a liquid and contains the liquid (16) to be dispensed at least in the vicinity of its outlet (13a), a volume of gas (VL) is drawn into the tip (13) via the outlet (13a) and a volume corresponding to the sum of the volume of liquid (VF) to be dispensed and the volume of gas (VL) is then supplied to the tip (13) in such a way that the volume of liquid (VF) is dispensed via the outlet (13a) in a contactless manner. The device comprises a plurality of dosing pumps that can be simultaneously actuated, in particular pipettes (2), which can be actuated by an injection plunger (6), in addition to a motor (1), which drives the injection plungers (6) and also a valve (3), which is located between the dosing pump and its respective tip (13) in order to fill each system completely with liquid without any gas.

Detachable tube assemblies, such as those useful in remote spraying devices, are disclosed. Tube segments are interconnected using radial extensions interfit with alignable radial holes on tubes to be coupled together. An actuator rod is provided with flexible barbs and a disk guide. The rod can be used to remotely actuate a spray.

An air-filled pipette for accurately metering small and large volumes of fluid samples is provided. The pipette has dual resolution capability such that the pipette can accurately aspirate a wide range of sample volumes and deliver them contact-free (touchless). The pipette may include an extension mandrel that reduces air space in a disposable tip within the pipette. The dual resolution capability and/or the extension mandrel also minimize errors associated with the compressibility of air. Multiple pipettes may also be arranged to form a pipetting module for the metering of multiple sample volumes simultaneously and automatically. The pipette includes a channel block having at least one cylindrical passage, that slides up and down over a rod, and a cylinder, with an axially extending passage therethrough, that is sized, shaped and aligned to fit into the cylindrical passage in a dynamic sealing relationship. A method for mixing multiple fluid samples within a pipette tip is also provided.

A system for delivery of a volume of infusible fluid. The system includes a controller configured to calculate a trajectory for delivering infusible fluid, the trajectory comprising at least one volume of fluid, and determine a schedule for delivering the at least one volume of fluid according to the trajectory, wherein the schedule comprising an interval and a volume of infusible fluid for delivery. The system also includes a volume sensor assembly for determining the at least one volume of fluid delivered, wherein the controller recalculates the trajectory based on the volume of fluid delivered.

A dispensing cartridge for a relatively precise dispensing of various fluids having a relatively wide range of viscosities is disclosed. The dispensing cartridge in accordance with the present invention is relatively simpler in configuration than known dispensing cartridges while minimizing leakage of the fluid and eliminating problems associated with chemical attack of the O-ring by the fluid in the dispensing cylinder. In particular, the dispensing cartridge in accordance with the present invention includes a cylinder; a piston with a central bore and a bleed plug. In order to simplify the design, the air vent is configured as a tortuous path, for example, a spiral path, defined by a spiral bleed plug, which in a pre-staged position, allows air to freely escape along the spiral path along the circumference of the plug. As the piston contacts the fluid, the forward motion of piston is resisted by the high back pressure created by the small effective diameter and relatively long length of the spiral path. Once the piston contacts the fluid, the spiral plug is pushed into the piston closing the spiral path. By controlling the fluid flow by way of a tortuous path, the amount of fluid backflow through the piston is minimized if not eliminated, thus eliminating the need for an annular overflow chamber, thereby simplifying the design of the piston. In order to minimize problems related to the sealing of the piston within the dispensing cartridge, the piston may be provided with one or more radially extending sealing lips. These sealing lips are used in lieu of or in conjunction with an O-ring. The sealing lips further simplify the design by eliminating the O-ring as well as the need for an annular chamber adjacent thereto as well as problems relating to chemical attack of the O-ring by the fluid within the dispensing cylinder. In an alternative embodiment for use that is particularly adapted with non-aggressive fluids, the piston is provided with a single sealing lip and an O-ring.

A drug dispensing system is provided that may be used universally and in which medical substances can be mixed with a carrier solution (13) in a simple manner. The device and system have a dispensing module (6) for medical substances and a hydrophilic nonwoven (14) with a carrier solution (13). The emission area of substance discharge openings (21, 22, 23, 24) of the dispensing module (6) are directed toward the nonwoven (14).

A fluid dispensing apparatus includes a mounting assembly having a plurality of mounting apertures and a plurality of fluid dispensing cartridges positioned within the mounting apertures. The mounting apertures and cartridges include matching cross-sectional profiles that lack symmetry. Each fluid dispensing cartridge includes a fluid reservoir, at least one valve, a metering chamber and a piston. The apparatus also includes a magnetic switch assembly controlling the movement of the piston and a means for damping the movement of the piston.

A system for capture of dose delivery information is provided. The system includes a medication delivery device, a dose information capture device adapted to he attached to the medication delivery device, and a target element adapted to be attached to the medication delivery device. The target element comprises a magnet or ferrous element and the target element attaches to the medication delivery device on a dose delivery mechanism of the medication delivery device. The dose information capture device includes a magnetic position sensor adapted to detect a position of the target element. As an alternative to magnetic sensing, MEMS flow sensors, and the like may also be used. Exemplary systems preferably transmit dose information in real time to remote devices for further processing,

A volume sensor-free microdosing device comprises a pressure chamber which is at least partly delimited by a displacer, an actuating device for actuating the displacer, the volume of the pressure chamber being adapted to the changed by actuating the displacer, a media reservoir which is in fluid communication with the pressure chamber, an outlet opening which is in fluid communication with the pressure chamber, and a control mechanism. The control mechanism drives the microdosing device in such a way that a small change of volume of the pressure chamber volume is effected per unit time by a movement of the displacer from a first position to a predetermined second position, the second position of the displacer defining a larger volume of the pressure chamber than the first position, so as to suck a fluid volume into the pressure chamber, and that, in a second phase, a large volume change of the pressure chamber volume is effected per unit time by a movement of the displacer from the second position to the first position, so as to eject a defined fluid volume from the outlet opening in this way.

Containers and methods are disclosed whereby portions of an available stand-by supply of flowable material within a container may be dispensed substantially immediately on-demand. Preferably, the containers include an open-ended container shell having a resilient, shape-retaining side wall defining an interior space, a liner positioned within the interior space of the container shell, and a cap closing the open-ended container shell to seal the liner against leakage of flowable material. The liner has a flaccid liner body for containing a flowable material to be dispensed. The cap has a discharge opening to allow an amount of flowable material to be discharged therethrough from the liner body. Importantly, the container includes a valve system which includes one-way discharge and inlet valves. The one-way discharge valve allows only flowable material to be discharged from the liner via the discharge opening, but prevents ambient air from being introduced into the liner when the discharge of flowable material is finished. The one-way inlet valve serves to trap air within the interior space of the container shell in response to a collapsing force applied against the side wall of the container shell which, in turn, allows ambient air to enter the interior space when such collapsing force is removed.

An apparatus and means of repeatedly dispensing controlled doses of liquid.

Liquid measuring and dispensing devices measure and dispense a quantity of cooking oil or other liquids or flowable powders. The liquid measuring and dispensing device attaches directly to the bottle containing the material, eliminating the need to search for measuring instruments when one desires to measure a quantity of material. Because of the direct bottle attachment, it is impossible to spill the material during the measuring process. Furthermore, because the use of external measuring instruments is eliminated, there is no cleaning process required after measuring and dispensing a quantity of material.