81 results about "Cannabis" patented technology

A harvester for removing cannabis flower from stalks includes a blade follower iris that adjusts the size of the flower-stripping opening to correspond to the diameter of the stalk. The size of the opening may be controlled by centrifugal and spring forces that cause the iris to open and close. In addition, an improved stalk-pulling belt drive conveyor system utilizes two relatively floating, releasably coupled belt systems to pinch and pull the stalk through the blade follower iris.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant comprising a quantitative trait locus (QTL) or a causal polymorphism associated with a flower density trait, and to Cannabis spp. plants having a flower density trait of interest comprising defined allelic states of polymorphisms defining the QTL or defined allelic states of causal polymorphisms provided herein. Also provided are Cannabis spp. plants with a flower density trait of interest comprising defined allelic states of polymorphisms and plants identified, characterized or produced by the methods described. Further provided are methods of marker assisted selection, genomic selection, marker assisted breeding, and genetic modification, for obtaining plants having a flower density trait of interest.

The present invention relates to an extract of in vitro cultured C. sativa root tissues, characterized in that said extract comprises at least one lignanamide. The present invention also relates to a pharmaceutical, dermatological, nutraceutical, or cosmetic composition comprising, as an active ingredient, the extract described above.

The present invention describes a method for the large-scale production of Cannabis sp. seedlings using the mini-cuttings technique. The process involves establishing a clonal mini-garden with super-dense planting of mini-stock plants trained in a "cup" form, optimizing use of the available space and significantly increasing productivity per unit area. An inert substrate is used, such as sand and expanded perlite, although variations such as vermiculite, carbonized rice husk, or coconut fiber can be employed without compromising efficiency. Environmental control is automated, ensuring ideal conditions of temperature, humidity, and photoperiod, maintained by means of artificial lighting, such as full-spectrum LED lamps operating for at least 18 hours per day to keep the plants in a continuous vegetative state. The invention offers significant advantages in terms of efficiency, genetic quality, sustainability, and reduction of operating costs, meeting the demands of the medicinal and industrial markets for high-quality Cannabis sp. products. By enabling the accelerated production of uniform clonal seedlings, the method has the potential to revolutionize cannabis cultivation practices.

A gas jet sieve trichome separation assembly is employed in use to separate trichomes from source plant material, such as separating kief from cannabis source plant material. The gas jet sieve trichome separation assembly, as well as an associated method of its operation, serves to separate and collect trichomes in a manner that has proven more effective and efficient than past techniques, and in a manner that facilitates enhanced automation and that is intended for larger scale production capabilities. Per various implementations, the gas jet sieve trichome separation assembly has a housing, one or more sieves, one or more rotatable arms, one or more actuators, a vacuum source, and a cyclonic separator.

The invention relates to a preparation method of fructus cannabis active polypeptide, which comprises the following steps: soaking degreased fructus cannabis meal in water for several hours, fishing out, freezing and melting twice, grinding into thick liquid, adding bromelain into the thick liquid for hydrolysis, and after the first hydrolysis, adding aspergillus niger acid protease for second hydrolysis; and after the secondary hydrolysis is finished, carrying out enzyme deactivation on the hydrolysate, centrifuging to remove unhydrolyzed precipitates, taking supernate, collecting filtrate by using a 2000Da ultrafiltration device, and concentrating and drying the filtrate to obtain the fructus cannabis active polypeptide powder. The fructus cannabis active polypeptide prepared by the preparation method disclosed by the invention has the effects of exciting the activity of ethanol dehydrogenase and inhibiting the activity of tyrosinase, and can be used as a raw material of functional food or cosmetics.

Provided herein is the identification of markers and genes associated with flower initiation in Cannabis. The markers are useful for breeding Cannabis plants that initiate flowering at longer daylengths, which allow for earlier maturation and harvesting and ability to grow outdoors at different latitudes or in greenhouses without artificial light deprivation. Also provided are methods for selecting plants by obtaining nucleic acids and detecting one or more markers that indicate flower initiation at increased daylight hours in order to establish plant lines having shorter harvest period as a result of flowering at increased daylight hours.

The present invention relates to the process of enrichment of Phytocannabinoids namely CBD and Δ9-THC from the dried aerial part (leaves and inflorescence) of Cannabis sativa. The present invention also relates to the preparation of formulation having enriched CBD and THC by combining with appropriate acceptable excipients such as nutriose, dextrin and maltodextrin. The present invention also discloses the use of the phytocannabanoids enriched blend for the management of pain including cancer pain & general pain.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant with respect to a flowering time trait comprising genotyping the plant for a quantitative trait locus (QTL) associated with a flowering time trait, and to methods of producing plants having a flowering time trait of interest based on defined allelic states of polymorphisms defining the QTL. Also provided are Cannabis spp. plants having a flowering time trait of interest comprising defined allelic states of polymorphisms defining the QTL and plants identified, characterized or produced by the methods described herein. The invention further relates to marker assisted selection and marker assisted breeding methods, in particular using a combination of specific markers provided, for obtaining plants having a flowering time trait of interest or for modulating the flowering time of cannabis plants.

Methods and apparatus for sterilizing plant material include disposing plant material in a sub-atmospheric pressure environment, dispersing a non-toxic, non-polymerizable gas into the sub-atmospheric pressure environment, applying an electric field to change the gas into cold plasma, and maintaining exposure of the plant material to the cold plasma until substantially sterilized plant material is obtained, wherein an amount of at least one active constituent in the plant material is substantially unchanged by the sterilizing. The plant material may be cannabis.

Provided herein is the identification and markers and causal genes associated with day-neutral autoflowering in plants and their use in selecting plants, including Cannabis plants, having autoflowering activity. The markers are useful for breeding autoflowering plants by obtaining nucleic acids, detecting one or more markers that indicate autoflowering activity, and establishing plant lines having such characteristics. Also provided are methods of editing plants to establish plant lines having autoflowering allelic variations.

The application discloses a method for ultrasonic regulation and control of functional properties of acidified cannabis sativa L. protein and application thereof. The application fully hydrates the cannabis sativa L. protein under acidification conditions, combines ultrasonic pretreatment, and performs heat induction to make the protein have ordered aggregation with enriched beta-folding, and meanwhile, improve the functional properties of the protein: the gel strength is 12.37 g under 60% ultrasonic power, which is about 33% higher than that of a non-ultrasonic control, the cohesiveness is 8.6 g, the emulsion stability is 185.89 min, which is about 2.6 times higher than that of the non-ultrasonic control, the apparent viscosity is improved and presents shear thinning behavior (power law index n1 < 1), and the strain breakage resistance is enhanced. The method can simultaneously regulate and control the ordered aggregation degree, gel property, emulsification and rheological property of the cannabis sativa L. protein, is suitable for strong acid type plant protein beverages, acid emulsions and high-acid gel food systems, and has the advantages of simple process, green safety and the like.

This invention relates to a novel cannabinoid oral pharmaceutical dosage form based on a Type IV or Type IV-like formulation classified using a Lipid Formulation Classification System. The formulation is contained in a container. "Type IV-like" means that the formulation is oil-free, for example, free of triglycerides or mixed glycerides.

The present invention relates to a composition for protecting nerve cells, comprising a supercritical extract of Cannabis sativa and, more specifically, to a composition for protecting nerve cells, comprising a supercritical extract of Cannabis sativa, thereby exhibiting an antioxidant effect and a nerve cell death inhibitory effect.

The invention provides an umbilicus application suppository for treating constipation and a preparation method thereof, and relates to the technical field of medicine.The umbilicus application suppository for treating constipation comprises a suppository body, the suppository body comprises a suppository matrix and a traditional Chinese medicine microcapsule, and the traditional Chinese medicine microcapsule comprises an emulsified oil phase, an emulsified water phase and a traditional Chinese medicine composition; the traditional Chinese medicine composition comprises rheum officinale, fructus cannabis, bunge cherry seeds, astragalus membranaceus, ginseng, immature bitter oranges, mangnolia officinalis, rhizoma atractylodis, radix sophorae flavescentis, golden cypress, fructus cnidii and fructus evodiae. A transdermal promotion mechanism is designed and optimized by adopting a traditional Chinese medicine micro-capsule structure, and a specific traditional Chinese medicine composition and a micro-encapsulation process are combined, so that the transdermal absorption efficiency of the medicine is effectively improved, the skin irritation reaction is reduced, and meanwhile, the stable slow release of the medicine is realized, thereby solving the problems of low transdermal absorption efficiency, large effect fluctuation, poor skin compatibility and the like in the prior art; the preparation has the advantages of high transdermal absorption efficiency, small skin irritation, good drug sustained release performance and the like.

This document describes methods and compositions for preventing hermaphroditism in Cannabis plants, as well as methods and compositions for making male sterile Cannabis plants.

The present invention discloses systems, devices, and methods for symphasic closed-cycle heat exchange, applicable to processes for extraction of compounds from biological materials, such as cannabis and other plants; said systems, devices, and methods incorporating a closed-cycle refrigeration circuit to provide energy savings and other improvements over existing single loop closed-cycle extraction processes.

System and method for infusing cannabis flower with one or more terpenes, THC, CBD, or any combination thereof. Embodiments include tumbling cannabis flower in a rotating treatment vessel, such as in a closed-loop system, while exposing the cannabis flower to an atomized liquid comprising one or more terpenes, THC distillate, or CBD distillate.

The application discloses a traditional Chinese medicine composition for treating constipation, which is prepared from the following traditional Chinese medicine extracts: 20-30 parts of radix rehmanniae preparata, 15-25 parts of fructus corni, 10-20 parts of radix scrophulariae, 10-20 parts of radix ophiopogonis, 10-20 parts of prunus domestica, 9-15 parts of semen platycladi, 10-20 parts of semen cannabis, 4-6 parts of semen abri, 10-20 parts of bombyx batryticatus, 8-12 parts of angelica sinensis, 8-12 parts of salvia miltiorrhiza, 3-8 parts of prunus armeniaca, 8-12 parts of platycodon grandiflorum, 8-12 parts of fructus aurantii, 9-12 parts of pericarpium citri reticulatae, 4-8 parts of glycyrrhiza uralensis, and a preparation method thereof is disclosed. The application is used for treating constipation of the type of dry intestine due to yin deficiency by the treatment principles of tonifying kidney yin, tonifying heart yin, moistening the intestines, moistening the intestines with pungent flavor, promoting lung and regulating qi, lifting the cover of the pot, regulating qi and invigorating the spleen, and regulating and protecting the spleen and stomach.

Provided is use of MfERF026 regulation in growth, development, and stress tolerance of Medicago sativa, which belongs to the technical field of plant genetic engineering. Provided is use of a regulatory agent for MfERF026, which is an ethylene responsive factor (ERF) in Medicago falcata, in promoting growth and development and improving drought tolerance and cold tolerance of M. sativa. The inhibited expression of MfERF026, the ERF in M. falcata may enhance the drought tolerance and cold tolerance of the M. sativa. Moreover, the inhibited expression of MfERF026, the ERF in M. falcata, may regulate the growth and development of M. sativa, thereby accelerating the growth rate of M. sativa to increase the number of leaves. The inhibited expression of MfERF026 provides a novel theoretical basis and a candidate gene for cultivating novel leguminous forage varieties with high resistance, yield, and protein content.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant comprising a quantitative trait locus (QTL) or a causative polymorphism associated with pathogen resistance, and to Cannabis spp. plants having a pathogen resistance trait of interest comprising defined allelic states of polymorphisms defining the QTL. Also provided are plants with a pathogen resistance trait of interest identified by the methods described herein. The invention further relates to marker assisted selection and marker assisted breeding methods for obtaining plants having a pathogen resistance trait of interest, as well as to methods of producing Cannabis spp. plants with the pathogen resistance trait of interest and plants produced by these methods, based on the allelic state of the QTLs or the causative polymorphism.

The present disclosure concerns a group of cannabinoid compounds defined by formulas (I) to (IV), wherein R1 is —H or —COOH, for the first time isolated and fully characterized in structure, absolute stereochemistry by the present applicant. Methods of isolation, characterization, stereoselective synthesis, biological activity, pharmaceutical composition and therapeutic applications of the present compounds as modulators of the cannabinoid CB1 receptor are also object of the disclosure.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a medicinal and edible traditional Chinese medicine composition with a bowel relaxing function and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 4-10 parts of bunge cherry seeds, 2-7 parts of fructus perillae, 3-8 parts of fructus cannabis, 2-5 parts of rhizoma polygonati, 2-5 parts of mulberries and 1-5 parts of semen raphani. The raw materials of the traditional Chinese medicine composition are homologous in medicine and food, no toxic or side effect exists, the preparation method is easy to operate, preliminary experiments verify that the traditional Chinese medicine composition can remarkably promote gastrointestinal motility, relax bowel and increase relative abundance of lactobacillus, and the traditional Chinese medicine composition has the potential of industrial production and popularization.

Apparatuses, methods, and systems for extraction, isolation, purification, and conversion of various cannabinoids, and modifications of whole-plant hemp extracts therewith are presented. A method for preparing a whole-plant hemp extract based product includes extracting cannabinoids from plant materials, such as one or more hemp varieties of Cannabis sativa. The method also includes separating and purifying CBD from the extracted cannabinoids, converting purified CBD to Δ9-THC and Δ8-THC and concurrently converting Δ9-THC to CBN, purifying and separating the CBN, and combining the purified CBN with a whole-plan hemp extract. Products and supplements related to the method are also described.

The invention discloses a traditional Chinese medicine compound preparation for treating constipation and a preparation method of the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation is prepared from 20-90 g of radix astragali, 10-60 g of raw rhizoma atractylodis macrocephalae, 10-15 g of peach kernels, 30-60 g of fructus cannabis, 30-45 g of herba leonuri, 6-60 g of raw radix et rhizoma rhei, 30-60 g of fried fructus aurantii immaturus, 15-30 g of ginger processed cortex magnoliae officinalis, 15-20 g of pogostemon cablin, 15-30 g of fried betel nuts, 10-30 g of fried semen raphani, 3-6 g of stevia rebaudiana leaves, 3-10 g of agilawood, 15-30 g of pericarpium citri reticulatae and 10-15 g of radix aucklandiae. The traditional Chinese medicine compound preparation disclosed by the invention has the beneficial effect of comprehensively treating constipation through compatibility of various medicinal materials. Firstly, radix astragali has the effects of enhancing immunity and regulating spleen and stomach functions, and can improve intestinal tract movement and promote digestion and absorption of food; and the raw bighead atractylodes rhizome has the effects of invigorating spleen and replenishing qi, can regulate the transportation and transformation functions of spleen and stomach, and is beneficial to improving the root cause of constipation. The peach kernels and the fructus cannabis have the effect of relaxing bowel, and can promote peristalsis of intestinal tracts.

The application belongs to the technical field of content detection, and discloses a kind of HPLC detection methods for simultaneously determining the content of multiple components in semen Cannabis capsules.The detection method includes mixing reference solution, chrysophanol and methanol to obtain mixed reference solution.The reference solution includes physcion solution, magnolol solution, houpo chrysophanol solution, emodin solution, rhein solution, nobiletin solution, aloe emodin solution, hesperidin solution and paeoniflorin solution;The contents of semen Cannabis capsules are mixed with methanol, and the test solution is obtained after heating and refluxing;The mixed reference solution and test solution are respectively sucked and injected into high performance liquid chromatograph.The detection method can simultaneously determine the content of multiple index components, can comprehensively reflect the quality of the preparation, and the test method has excellent precision, repeatability, stability and high sample recovery rate.

The utility model discloses a cannabis oil processing and cleaning device, and relates to the field of cleaning equipment, the cannabis oil processing and cleaning device comprises an insertion rod and a cleaning unit arranged on the peripheral wall of the insertion rod, and an extrusion unit is arranged on the insertion rod. The utility model discloses a cannabis oil processing and cleaning device. According to the cannabis oil processing and cleaning device, when an inserting rod is inserted into the inner wall of an oil pressing pipe, the end of an extrusion plate makes contact with the end of the oil pressing pipe, at the moment, by moving an adjusting base, the adjusting base pushes a rotating rod to rotate, the rotating rod pushes the extrusion plate to move, and a brush on the extrusion plate makes contact with the inner wall of the oil pressing pipe; and a handle is rotated to drive an inserting rod to rotate, so that the inserting rod drives a cleaning unit to rotate, a hairbrush on an extrusion plate rotates, the inner wall of the oil pressing pipe is cleaned, the cleaning completeness of the inner wall of the oil pressing pipe is guaranteed, and the cleaning cleanliness is improved.

The unique annual herbaceous Cannabis plant variety ‘ESB-1’ is provided. The variety can be distinguished by its outstanding features of a THCV cannabinoid content ratio of about 1 part THC to 1 part THCV and purple leaf stem, when grown under certain growing conditions.