40 results about "Cannabis" patented technology

A harvester for removing cannabis flower from stalks includes a blade follower iris that adjusts the size of the flower-stripping opening to correspond to the diameter of the stalk. The size of the opening may be controlled by centrifugal and spring forces that cause the iris to open and close. In addition, an improved stalk-pulling belt drive conveyor system utilizes two relatively floating, releasably coupled belt systems to pinch and pull the stalk through the blade follower iris.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant comprising a quantitative trait locus (QTL) or a causal polymorphism associated with a flower density trait, and to Cannabis spp. plants having a flower density trait of interest comprising defined allelic states of polymorphisms defining the QTL or defined allelic states of causal polymorphisms provided herein. Also provided are Cannabis spp. plants with a flower density trait of interest comprising defined allelic states of polymorphisms and plants identified, characterized or produced by the methods described. Further provided are methods of marker assisted selection, genomic selection, marker assisted breeding, and genetic modification, for obtaining plants having a flower density trait of interest.

The present invention relates to an extract of in vitro cultured C. sativa root tissues, characterized in that said extract comprises at least one lignanamide. The present invention also relates to a pharmaceutical, dermatological, nutraceutical, or cosmetic composition comprising, as an active ingredient, the extract described above.

The present invention describes a method for the large-scale production of Cannabis sp. seedlings using the mini-cuttings technique. The process involves establishing a clonal mini-garden with super-dense planting of mini-stock plants trained in a "cup" form, optimizing use of the available space and significantly increasing productivity per unit area. An inert substrate is used, such as sand and expanded perlite, although variations such as vermiculite, carbonized rice husk, or coconut fiber can be employed without compromising efficiency. Environmental control is automated, ensuring ideal conditions of temperature, humidity, and photoperiod, maintained by means of artificial lighting, such as full-spectrum LED lamps operating for at least 18 hours per day to keep the plants in a continuous vegetative state. The invention offers significant advantages in terms of efficiency, genetic quality, sustainability, and reduction of operating costs, meeting the demands of the medicinal and industrial markets for high-quality Cannabis sp. products. By enabling the accelerated production of uniform clonal seedlings, the method has the potential to revolutionize cannabis cultivation practices.

Provided herein is the identification of markers and genes associated with flower initiation in Cannabis. The markers are useful for breeding Cannabis plants that initiate flowering at longer daylengths, which allow for earlier maturation and harvesting and ability to grow outdoors at different latitudes or in greenhouses without artificial light deprivation. Also provided are methods for selecting plants by obtaining nucleic acids and detecting one or more markers that indicate flower initiation at increased daylight hours in order to establish plant lines having shorter harvest period as a result of flowering at increased daylight hours.

The invention relates to methods of identifying and characterizing a Cannabis spp. plant with respect to a flowering time trait comprising genotyping the plant for a quantitative trait locus (QTL) associated with a flowering time trait, and to methods of producing plants having a flowering time trait of interest based on defined allelic states of polymorphisms defining the QTL. Also provided are Cannabis spp. plants having a flowering time trait of interest comprising defined allelic states of polymorphisms defining the QTL and plants identified, characterized or produced by the methods described herein. The invention further relates to marker assisted selection and marker assisted breeding methods, in particular using a combination of specific markers provided, for obtaining plants having a flowering time trait of interest or for modulating the flowering time of cannabis plants.

Methods and apparatus for sterilizing plant material include disposing plant material in a sub-atmospheric pressure environment, dispersing a non-toxic, non-polymerizable gas into the sub-atmospheric pressure environment, applying an electric field to change the gas into cold plasma, and maintaining exposure of the plant material to the cold plasma until substantially sterilized plant material is obtained, wherein an amount of at least one active constituent in the plant material is substantially unchanged by the sterilizing. The plant material may be cannabis.

The application discloses a method for ultrasonic regulation and control of functional properties of acidified cannabis sativa L. protein and application thereof. The application fully hydrates the cannabis sativa L. protein under acidification conditions, combines ultrasonic pretreatment, and performs heat induction to make the protein have ordered aggregation with enriched beta-folding, and meanwhile, improve the functional properties of the protein: the gel strength is 12.37 g under 60% ultrasonic power, which is about 33% higher than that of a non-ultrasonic control, the cohesiveness is 8.6 g, the emulsion stability is 185.89 min, which is about 2.6 times higher than that of the non-ultrasonic control, the apparent viscosity is improved and presents shear thinning behavior (power law index n1 < 1), and the strain breakage resistance is enhanced. The method can simultaneously regulate and control the ordered aggregation degree, gel property, emulsification and rheological property of the cannabis sativa L. protein, is suitable for strong acid type plant protein beverages, acid emulsions and high-acid gel food systems, and has the advantages of simple process, green safety and the like.

This invention relates to a novel cannabinoid oral pharmaceutical dosage form based on a Type IV or Type IV-like formulation classified using a Lipid Formulation Classification System. The formulation is contained in a container. "Type IV-like" means that the formulation is oil-free, for example, free of triglycerides or mixed glycerides.

The present invention relates to a composition for protecting nerve cells, comprising a supercritical extract of Cannabis sativa and, more specifically, to a composition for protecting nerve cells, comprising a supercritical extract of Cannabis sativa, thereby exhibiting an antioxidant effect and a nerve cell death inhibitory effect.

The present invention discloses systems, devices, and methods for symphasic closed-cycle heat exchange, applicable to processes for extraction of compounds from biological materials, such as cannabis and other plants; said systems, devices, and methods incorporating a closed-cycle refrigeration circuit to provide energy savings and other improvements over existing single loop closed-cycle extraction processes.

System and method for infusing cannabis flower with one or more terpenes, THC, CBD, or any combination thereof. Embodiments include tumbling cannabis flower in a rotating treatment vessel, such as in a closed-loop system, while exposing the cannabis flower to an atomized liquid comprising one or more terpenes, THC distillate, or CBD distillate.

The application discloses a traditional Chinese medicine composition for treating constipation, which is prepared from the following traditional Chinese medicine extracts: 20-30 parts of radix rehmanniae preparata, 15-25 parts of fructus corni, 10-20 parts of radix scrophulariae, 10-20 parts of radix ophiopogonis, 10-20 parts of prunus domestica, 9-15 parts of semen platycladi, 10-20 parts of semen cannabis, 4-6 parts of semen abri, 10-20 parts of bombyx batryticatus, 8-12 parts of angelica sinensis, 8-12 parts of salvia miltiorrhiza, 3-8 parts of prunus armeniaca, 8-12 parts of platycodon grandiflorum, 8-12 parts of fructus aurantii, 9-12 parts of pericarpium citri reticulatae, 4-8 parts of glycyrrhiza uralensis, and a preparation method thereof is disclosed. The application is used for treating constipation of the type of dry intestine due to yin deficiency by the treatment principles of tonifying kidney yin, tonifying heart yin, moistening the intestines, moistening the intestines with pungent flavor, promoting lung and regulating qi, lifting the cover of the pot, regulating qi and invigorating the spleen, and regulating and protecting the spleen and stomach.

Provided is use of MfERF026 regulation in growth, development, and stress tolerance of Medicago sativa, which belongs to the technical field of plant genetic engineering. Provided is use of a regulatory agent for MfERF026, which is an ethylene responsive factor (ERF) in Medicago falcata, in promoting growth and development and improving drought tolerance and cold tolerance of M. sativa. The inhibited expression of MfERF026, the ERF in M. falcata may enhance the drought tolerance and cold tolerance of the M. sativa. Moreover, the inhibited expression of MfERF026, the ERF in M. falcata, may regulate the growth and development of M. sativa, thereby accelerating the growth rate of M. sativa to increase the number of leaves. The inhibited expression of MfERF026 provides a novel theoretical basis and a candidate gene for cultivating novel leguminous forage varieties with high resistance, yield, and protein content.

The present disclosure concerns a group of cannabinoid compounds defined by formulas (I) to (IV), wherein R1 is —H or —COOH, for the first time isolated and fully characterized in structure, absolute stereochemistry by the present applicant. Methods of isolation, characterization, stereoselective synthesis, biological activity, pharmaceutical composition and therapeutic applications of the present compounds as modulators of the cannabinoid CB1 receptor are also object of the disclosure.

The unique annual herbaceous Cannabis plant variety ‘ESB-1’ is provided. The variety can be distinguished by its outstanding features of a THCV cannabinoid content ratio of about 1 part THC to 1 part THCV and purple leaf stem, when grown under certain growing conditions.

The present invention relates to a rapid and accurate method for identifying haploid plants derived from crosses between Cannabis donor lines and natural inducer lines. The method comprises: sequencing maternal and paternal lines using whole genome sequencing (WGS); identifying contrasting molecular markers between maternal and paternal lines; developing diagnostic primers targeting the molecular marker; and screening F1 progeny with one-shot PCR to detect genotype indicative of haploidy.

The invention provides a transcription factor CsNF-YA and application thereof in positive regulation of CsCBCAS gene expression of China-hemp, and belongs to the technical field of gene engineering. The invention provides a transcription factor CsNF-YA, and the nucleotide sequence of the transcription factor CsNF-YA is as shown in SEQ ID No.2. The transcription factor CsNF-YA is screened from a China-hemp yeast cDNA library, the transcription factor CsNF-YA can be specifically combined with a China-hemp CsCBCAS gene promoter, expression of the CsCBCAS gene can be remarkably promoted by overexpression of the transcription factor CsNF-YA, and the transcription factor CsNF-YA can be applied to synthesis genetic improvement of China-hemp CBC.

The invention relates to the field of traditional Chinese medicine, and particularly discloses a spleen-tonifying intestine-moistening traditional Chinese medicine composition and an application method thereof in functional constipation. The spleen-tonifying intestine-moistening traditional Chinese medicine composition comprises the following components in parts by weight: roasted rhizoma atractylodis macrocephalae, codonopsis pilosula, poria cocos, pericarpium citri reticulatae, fructus cannabis and bunge cherry seeds; the formula is accurately matched with the core pathogenesis of spleen dysfunction in transportation and intestine dysfunction in moistening, the roasted rhizoma atractylodis macrocephalae, the codonopsis pilosula and the like are used for invigorating the spleen and replenishing qi to consolidate the root, the fructus cannabis and the bunge cherry seeds are used for relaxing bowel to treat the symptoms, the defect of emphasizing a single effect is avoided, and the formula is suitable for multi-subtype constipation, and has the advantages of no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect, no toxic or side effect and the like. The traditional Chinese medicine is especially suitable for patients with spleen-stomach deficiency with intestinal dryness type functional constipation.

The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine formula for regulating comprehensive metabolism, a tea drink and a preparation method. The formula consists of dried orange peel, rose, Chinese angelica, prepared rehmannia root, corn stigma, fragrant solomonseal rhizome, white paeony root, fried malt, cassia seed, vinegar bupleurum chinense, turmeric root-tuber, dried ginger, medlar, tuckahoe, madder, dwarf lilyturf tuber, immature bitter orange, astragalus root, hemp seed, coix seed and dahurian angelica root according to a specific weight ratio. The traditional Chinese medicine organically combines treatment methods of soothing liver and regulating qi, tonifying spleen and clearing damp, nourishing yin and blood, relaxing bowel and the like, and systematic regulation of sugar, fat and energy metabolism of a human body is realized through synergistic compatibility of monarch, minister, assistant and guide. Compared with the prior art, the tea not only can effectively assist in reducing fat and improving glycolipid metabolism indexes, but also can synchronously promote intestinal tract movement, improve sleep rhythm and internally regulate so as to improve skin gloss and color, and a safe and convenient tea drink solution with comprehensive conditioning benefits is provided.

A process for stabilising a macerated oil comprising a liquid carrier and a compound soluble in said carrier and containing at least one cannabinoid, characterised in that it brings about a removal of oxygen from the liquid carrier before, during or after the dissolution of the soluble compound.

The utility model relates to the technical field of fructus cannabis peptide extraction equipment, discloses an efficient fructus cannabis peptide extraction and separation device, and solves the problems that residual impurities after extraction can be adsorbed on the inner wall of an extraction tank and a floating plate and need to be cleaned manually, and the labor cost is increased. Connecting blocks are installed at the two ends of the base, a first motor is installed in the base, a supporting disc is arranged on the upper side of the base, a plurality of guide blocks are installed on the outer side of the supporting disc, a plurality of sliding grooves are formed in the inner wall of the extraction tank, a scraping ring is installed on the upper side of the supporting disc, and a threaded rod penetrates through the middle of the supporting disc in a threaded mode. The driving end of the first motor drives the threaded rod to rotate, the threaded rod rotates to drive the supporting disc to move upwards along the sliding groove, so that the scraping ring scrapes impurities on the inner wall of the extraction tank, the impurities fall on the supporting disc, and when the supporting disc ascends to the upper end of the extraction tank, a worker can collect the impurities on the supporting disc.

The method comprises the following steps: crushing and homogenizing fructus cannabis, poria cocos and herba cistanche, carrying out compound fermentation by using aspergillus oryzae, aspergillus niger and kluyveromyces marxianus, then mixing with angelica sinensis and bunge cherry seeds, and carrying out two-phase extraction by using a pulsed magnetic field-deep eutectic solvent to enrich active ingredients; the semen cannabis extract, the collagen peptide and the donkey-hide gelatin are wrapped with the psyllium husk dietary fiber-hyaluronic acid gel to form an inner core, and the outer layer is wrapped with a modified pullulan-elastin network. According to the invention, hydrophilic / hydrophobic active components are synchronously released, a gel-elastin double-layer structure protects the active components from being damaged by gastric acid, tannic acid can efficiently cross-link inner core components to strengthen structural stability, tea polyphenol modified pullulan can enable outer layers to be combined with elastin to improve intestinal tract adhesiveness, and then long-acting slow release is realized; the effects of relaxing bowel, expelling toxins, beautifying and resisting oxidation are remarkably improved, and the composition is safe, mild and higher in bioavailability.

This invention provides enzymes and methods for synthesizing cannabinoids specifically and in high yield. [Solution] A method is provided for producing one or more cannabinoids, comprising the step of contacting cannabigerol acid with a cannabinoid synthase ortholog. The cannabinoid synthase ortholog is derived from an organism other than hemp (Cannabis sativa). Also disclosed are recombinant cells of Saccharomyces cerevisiae or Pichia pastoris, which contain nucleic acids encoding the cannabinoid synthase ortholog in their genome. The cannabinoid synthase ortholog is expressed in its active form in the recombinant cells.

An electrostatic separation apparatus and method are provided for isolating glandular trichomes from trichome-bearing plant biomass such as cannabis, hemp, or hops. The system may include a vertically oriented particle transport assembly configured to convey a sample through a linear free-fall pathway, a separation chamber with opposing electrode assemblies generating a uniform electrostatic field, and discharge electrodes positioned below the chamber to neutralize residual charge. Airflow regulation may be achieved through laminar diffuser plates and periodic vibration of critical components, including the hopper and diffuser, to prevent clogging and maintain uniform flow. The hopper may further include a circular discharge spout and rounded internal fillets to prevent bridging and ensure consistent powder recirculation. The apparatus achieves high-purity trichome separation through controlled field exposure, aerodynamic stabilization, and charge-neutralized particle discharge, enabling continuous, high-throughput operation with improved yield, reduced maintenance, and enhanced reproducibility across successive processing cycles.

The invention discloses a traditional Chinese medicine composition for treating yin deficiency and intestine dryness type constipation. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 10-20 parts of bunge cherry seeds, 10-20 parts of platycladi seeds, 9-15 parts of fructus cannabis, 8-20 parts of angelica sinensis, 10-16 parts of radix scrophulariae, 9-15 parts of radix ophiopogonis, 9-15 parts of bran-fried fructus aurantii, 9-15 parts of pericarpium citri reticulatae and 3-6 parts of liquorice. The invention further discloses a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition disclosed by the invention can obviously improve the problems of strenuous defecation, dry and hard stool and the like of functional constipation patients and improve the life quality of the patients.

The invention relates to a small-scale delivery system of a nutrient solution for increasing inflorescences and cannabinoid yield of cannabis plants and a method thereof, wherein the nutrient solution is a water solution of saccharides in their preferred amounts, while other nutrients can be optionally present. The delivery system comprises at least one container filled with the nutrient solution, a dosing device and infusion means. The dosing device pushes the solution out of the container and into the cannabis plant through the infusion means over a determined time period. The method according to the invention uses plant stem infusion for delivery of the nutrient solution into cannabis plants via a defined flow regime. The cannabinoid yield in the cannabis plant increased up to 34 wt.% compared control plants.

The invention relates to the technical field of agricultural facility light environment intelligent control, and discloses a special plant (such as cannabis sativa) specificity multi-band closed-loop regulation light source and a control method, and the method comprises the following steps: S1, configuring an independent / mixed multi-band adjustable light source module composed of high-precision LED chip arrays with at least five independent bands, the wave bands comprise an ultraviolet wave band, a blue light wave band, a green light wave band, a red light wave band and a far-red light wave band, the output light intensity of each wave band can be continuously and steplessly adjusted within a set range, and the wave bands can be independently controlled. Through the independent continuously-adjustable multi-band LED array, combined output in any proportion can be realized in a full spectrum range, spectrum mutation and physiological stress caused by traditional discrete band switching are avoided, the requirement differences of different genotypes and different growth stages of special crops (such as cannabis sativa) on UV, blue, green, red and far-red light can be accurately matched, and the application prospect is wide. Therefore, the photosynthetic efficiency and the balance of target secondary metabolite synthesis are improved.

Provided are therapeutic combinations, pharmaceutical compositions, and pharmaceutical kits comprising bioactive molecules from fungi, plants, and algae. In some embodiments, the fungi are from any psilocybin-producing fungi, such as from Psilocybe spp. fungi. In some embodiments, the plants are from either or both of the Cannabis and Dipteryx genera. In some embodiments, the algae may be marine algae, such as from the family Bangicacae, including the Pyropia and Porphyra genera. Methods of producing the disclosed combinations, compositions, and kits are also provided, such as using natural, biosynthetic, or synthetic means. Further provided are methods of using the disclosed combinations, compositions, and kits in treatment, and in particular for movement disorders, such as for Parkinson's disease, and the disclosed combinations are demonstrated to provide significant advantages in the treatment thereof.

The invention relates to the technical field of traditional Chinese medicine preparation, in particular to a traditional Chinese medicine composition for treating hypertension and a preparation method and application thereof. The traditional Chinese medicine composition comprises apocynum venetum, gastrodia elata, fructus cannabis, girald daphne bark, salvia miltiorrhiza, rhodiola rosea, gynostemma pentaphylla, corn stigma, dogwood and radix rehmanniae. The traditional Chinese medicine composition provided by the invention can stably reduce blood pressure and effectively eliminate headache, dizziness, palpitation, weakness and other symptoms caused by hypertension. The traditional Chinese medicine composition can effectively treat hypertension, and the effective rate is high and reaches 86% or above.