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5183 results about "Salicylic acid" patented technology

Salicylic acid is used on the skin to treat psoriasis and other dry, scaly skin conditions. This medication is also used to help remove dead skin from warts, the palms of the hands, and the soles of the feet.

Mixed micellar drug deliver system and method of preparation

Pharmaceutical compositions comprising a macromolecular pharmaceutical agent in micellar form are disclosed. The micelles are formed from an alkali metal alkyl sulfate, and at least one additional micelle-forming compound as described in the specification. An alkali metal salicylate and a pharmaceutically acceptable edetate are also included in the composition. Micelle size ranges between about 1 and 10 nanometers. Methods for making and using the compositions are also disclosed.
Owner:GENEREX PHARMA

Topical dermal anaesthetic

A liquid composition applied transdermally for relief of pain comprising alcohol in an amount by weight of about 57 to about 91 percent; glycerin in an amount by weight of about 1 to about 12 percent; an analgesic agent in an amount by weight of about 2 to about 28 percent, the analgesic agent comprising a derivative of salicylic acid; methylsulfonylmethane in an amount by weight of about 0.02 to 5 percent; and emu oil in an amount by weight of about 0.01 to 3 percent, the liquid composition permeating skin to relieve pain. The composition further comprising, as an additional feature, aloe vera in an amount by weight of at least about 0.05 percent and having an amount by weight of about 0.05 to 4 percent. The composition features transdermal pain relief such that a patient can apply the analgesic agent directly to an area of pain without such side effects as stomach irritation which is normally associated with aspirin. The composition may be sprayed or rolled directly onto the painful area. Because of the unique formula, the composition is safe to vital internal organs, requires no mixing before use, and is shelf stable for marketing purposes.
Owner:VELTRAN LP

Derivatives of 4- or 5-aminosalicylic acid

InactiveUS20060270635A1Less readily absorbedEasily reach colonBiocidePhosphorous compound active ingredientsThioester synthesisSalicylic acid
The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention / treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention / treatment of colon cancer.
Owner:ANTIBE THERAPEUTICS INC

Regulation of mammalian keratinous tissue using N-acyl amino acid compositions

InactiveUS20050019356A1Prevent and retardTreat uneven skin toneCosmetic preparationsToilet preparationsPlant sterolHydroxyproline
Skin care compositions containing N-acyl amino acid, particularly N-acyl derivatives of Phenylalanine or Tyrosine, their isomers, or their salts; at least one other skin care active selected from sugar amines, vitamin B3, retinoids, peptides, dialkanoyl hydroxyproline, hexamidine, salicylic acid, and phytosterol; and a dermatologically acceptable carrier for the N-acyl amino acid and the skin care active. The invention further relates to methods for regulating the condition of mammalian keratinous tissue wherein the methods each comprise the step of topically applying to the keratinous tissue of a mammal needing such treatment, a safe and effective amount of the skin care composition of the invention.
Owner:THE PROCTER & GAMBLE COMPANY

Saline-alkali soil improver

The invention relates to an improver for saline-alkali soil. The improver comprises a powder agent and a water agent, wherein the powder agent comprises the following components: organic matters, plant mycelium protein powder, active calcium, calcium superphosphate, aluminum sulfate, fatty alcohol polyoxyethylene ether ammonium sulfate, amino acid powder, bacillus subtilis and photosynthetic bacteria, and the water agent comprises the following components: citric acid, fulvic acid, humic acid, malic acid, maleic acid, fumaric acid, L-tartaric acid, pyrophosphoric acid, humic acid, lactic acid, oxalic acid, salicylic acid, sodium ion adsorbent, Tween-80 and water. The improver disclosed by the invention can improve the soil from multiple angles, namely soil structure, microorganism species, a chemical method and the like, obviously promote the release of iron and phosphorus in the soil, improve the soil structure, effectively reduce the content of sodium ions in the soil, reduce the pH value of the soil and restore land to a normal planting state after being used continuously for two years.
Owner:孙东军 +1

Biodegradable activators to gel silica sol for blocking permeability

A method of treating a treatment zone in a well to reduce the permeability of the treatment zone including the steps of: introducing into the treatment zone a water-based treatment fluid comprising: an aqueous silica sol; and a water-soluble chemical activator for gelling the silica sol, wherein the chemical activator is selected from the group consisting of: phytic acid, methylglycinediacetic acid, a water-soluble polyepoxysuccinic acid, salicylic acid, ascorbic acid, tannic acid, and an alkali metal salt or ammonium salt of any of the foregoing; and shutting in treatment zone for at least a sufficient time to allow the treatment fluid to in-situ form a solid gel at a design temperature for the method. Alternatively, a first treatment fluid including the aqueous silica sol and a second treatment fluid including the chemical activator can be introduced into the treatment zone separately, in any order.
Owner:HALLIBURTON ENERGY SERVICES INC

Methods and compositions for improved non-viral gene therapy

Methods to prevent or reduce inflammation secondary to administration of a lipid-nucleic acid complex in a subject, that include administering to the subject a non-steroidal anti-inflammatory agent, a salicylate, an anti-rheumatic agent, an antihistamine, or an immunsuppressive agent with the lipid-nucleic acid complex are disclosed. Also disclosed are methods of screening for inhibitors of the inflammatory response associated with administration of a lipid-nucleic acid complex to a subject, including providing a candidate substance suspected of preventing or inhibiting the inflammation associated with administration of a lipid-nucleic acid complex to the subject. Also disclosed are compositions that include a lipid, a nucleic acid, and a non-steroidal anti-inflammatory agent, a salicylate, an anti-rheumatic agent, an antihistamine, or an immunosuppressive agent.
Owner:BOARD OF RGT THE UNIV OF TEXAS SYST

Antimicrobial medical articles containing a combination of anti-infective compounds, octoxyglycerin, salicylic acid, and sesquiterpenoids

Medical articles impregnated with antimicrobial compositions containing synergistic combinations of octoxyglycerin and other anti-infective compounds are disclosed. Such medical articles may include urinary catheters, central venous catheters, tracheal catheters, arterial grafts, wound dressings, sutures, or any other medical articles derived from polymeric substrates such as biomedical polyurethane, biomedical polyvinylchloride (PVC), biomedical silicon, biodegradable polymers, polytetrafluoroethylene (PTFE), etc. or from natural products including natural rubber, silk or cotton fiber. Antimicrobial compositions comprising salicylic acid and sesquiterpenoids are also disclosed.
Owner:THE TRUSTEES OF COLUMBIA UNIV IN THE CITY OF NEW YORK

Lubricating oil compositions

Lubricating oil compositions having a sulfated ash content of no more than 1.0 mass %, which contain a major amount of oil of lubricating viscosity, a minor amount of calcium salicylate detergent, an amount of a magnesium-based detergent providing at least 200 ppm of magnesium, and a basic, low molecular weight, nitrogen-containing dispersant, which compositions provide improved top ring wear protection in internal combustion engines.
Owner:INFINEUM INT LTD

Composition and method of effecting superficial chemical skin peels

A method for effecting a superficial chemical skin peel is provided wherein a concentrated solution of salicylic acid in a dermatologically acceptable solvent is applied to be treated. The concentrated salicylic acid solution contains at least 15 wt % salicylic acid and preferably at least about 20 wt % salicylic acid, The composition and method are useful in the treatment of skin disorders such as photodamaged skin, hyperpigmentation, acne vulgaris, and the like.
Owner:KLIGMAN DOUGLAS E +1

Personal Care Compositions Containing Cationic Synthetic Copolymer and a Detersive Surfactant

A personal care composition comprising:a) a synthetic random copolymer having a net positive charge comprising;i.) a nonionic monomer unit of the following formula:where R is H or C1-4 alkyl; and R1 and R2 are independently selected from the group consisting of H, C1-4 alkyl, CH2OCH3, CH2OCH2CH(CH3)2, and phenyl, or together are C3-6cycloalkyl; andii.) a cationic monomer unit with 2 or more positive charges of the following formula:where each of v, v′, and v″ is independently an integer of from 1 to 6, w is zero or an integer of from 1 to 10, and X− is an anion.and;b) a detersive surfactant;c) an azole;d) salicylic acid ande) an aqueous carrier.
Owner:THE PROCTER & GAMBLE COMPANY

Hydrogen peroxide disinfectant containing a cyclic carboxylic acid and/or aromatic alcohol

An aqueous disinfecting solution and dry powdered composition which may be dissolved in water to provide the solution. The solution has a pH of from 0.6 to 7 and comprises (a) hydrogen peroxide in a concentration of from 0.01 to 6% w / w; and (b) at least one component chosen from cyclic carboxylic acids and aromatic alcohols, in a concentration of from 0.01 to 4 w / w %, all based on the total weight of the solution. The cyclic carboxylic acids are preferably 2-furan carboxylic acid, benzoic acid and salicylic acid. Furthermore, the solution preferably contains at least one C6-C12 alkyl diphenyl sulfonate surfactant and a nonionic surfactant. Additional optional ingredients include anionic surfactants, corrosion inhibitors, cation sequestering agents, and buffers.
Owner:JOHNSONDIVERSEY INC

Plant nutrient liquid fertilizer

InactiveCN102701861AImprove stress resistanceSolve the problem of lack of nutrientsFertilizer mixturesSucrosePhosphate
The invention relates to a plant nutrient liquid fertilizer. In order to solve the problem of over fertilization, the plant nutrient liquid fertilizer is prepared from the following raw materials in proportion by weight: aqua brassin 12-36, gibberellin 1-4, indoleacetic acid 30-80, abscisic acid 10-20, naphthaleneacetic acid 50-90, salicylic acid 80-180, vitamin C 1-3, cane sugar 40-100, chitin 20-80, 0.05-0.2 percent triacontanol 400-1,000, hydrolyzed protein 2-5, potassium dihydrogen phosphate 300-400, thiourea 40-120, cobalt chloride 5-12, borax 50-100, sodium silicate 30-55, urea 300-500, ammonium molybdate 50-80, copper sulfate 30-65, zinc sulfate 120-200, magnesium sulfate 100-150, calcium chloride 50-120, manganese sulfate 40-80 and water in the amount of 3-8 times the total amount of all the raw materials or water in the amount capable of dissolving all the raw materials, wherein the water is de-ionized water or micro cluster water; and the preparation method is that all the materials are prepared into aqueous solution. The plant nutrient liquid fertilizer has the advantages of favorably solving the problems of over fertilization and shortage of nutrient elements in soil, obviously improving the plant adverse resistance, improving the photosynthesis and the accumulation efficiency of nutritive materials and improving the yield and the quality.
Owner:魏玉芳

Derivaitves of 4-Or 5-Aminosalicylic Acid

InactiveUS20080207564A1Less readily absorbedEasily reach colonBiocideAntipyreticThioester synthesisSalicylic acid
The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) and for the prevention / treatment of colon cancer. More particularly, these derivatives comprise a hydrogen sulfide releasing moiety linked via an azo, an ester, an anhydride, a thioester or an amide linkage to a molecule of 4- or 5-aminosalicylic acid. Furthermore, the present invention provides a process for preparing these compounds and their use for treating IBD and IBS and the prevention / treatment of colon cancer.
Owner:ANTIBE THERAPEUTICS INC

Acne treatment powder foundation

Dry powder foundation formulations that include a sustained-release salicylic acid composition, an effective, buffering amount of one or more salicylate ions, and one or more of zinc and titanium oxides, and pigments or colorants, are disclosed. The formulations provide both acne treatment and prevention, and sunblock protection. The formulation can also include other sunblocking or sunscreen agents to prevent photoaging and sunburn, such as avobenzone, and 3-benzophenone, and other cosmetically-acceptable active agents and excipients.
Owner:AER LINGUS +1

Chemical mechanical polishing slurries and cleaners containing salicylic acid as a corrosion inhibitor

The invention provides methods for CMP polishing, residue removal and post-CMP polishing of a metal containing substrate. The CMP polishing methods for contacting a metal-containing substrate with a composition comprising an oxider, a salicylic acid compound, water, and an abrasive. The post-CMP polishing and residue removal methods require contacting a metal-containing substrate with a composition comprising an oxidizer, a salicylic acid compound, and water.
Owner:DUPONT AIR PRODS NANOMATERIALS

Fruit-vegetables antistaling agent, preparation and application thereof

The invention provides a fruit and vegetable fresh-keeping agent, a preparation method and application thereof. The fresh-keeping agent uses burdock fructo-oligosaccharides as main composition and combines aqueous solution prepared by chitosan, ascorbic acid, salicylic acid, calcium chloride and acetic acid to treat fruit and vegetable, so that a fruit and vegetable system can obtain the improved resistance, and a hyaloplasmic fresh-keeping membrane is formed on the surface of the fruit and the vegetable so as to effectively inhibit the growth of microbe, prevent moisture dissipation and contact between the fruit and the vegetable and air, and inhibit breath and transpiration, thereby greatly deferring aging of the fruit and the vegetable, and inhibiting putridity, mildew and rot. The fruit and vegetable fresh-keeping agent is applicable to storage and fresh-keeping for various fruits and vegetables with long fresh-keeping period and small consumption of nutrient materials.
Owner:SHANDONG UNIV

Hydrogen peroxide disinfectant containing a cyclic carboxylic acid and/or aromatic alcohol

An aqueous disinfecting solution and dry powdered composition which may be dissolved in water to provide the solution. The solution has a pH of from 0.6 to 7 and comprises (a) hydrogen peroxide in a concentration of from 0.01 to 6% w / w; and (b) at least one component chosen from cyclic carboxylic acids and aromatic alcohols, in a concentration of from 0.01 to 4 w / w %, all based on the total weight of the solution. The cyclic carboxylic acids are preferably 2-furan carboxylic acid, benzoic acid and salicylic acid. Furthermore, the solution preferably contains at least one C6-C12 alkyl diphenyl oxide sulfonate surfactant and a nonionic surfactant. Additional optional ingredients include anionic surfactants, corrosion inhibitors, cation sequestering agents, and buffers.
Owner:JOHNSONDIVERSEY INC

Scaling powder for no-clean lead-free low-silver welding paste

The invention discloses scaling powder for no-clean lead-free low-silver welding paste. The scaling powder comprises, by weight percentage, 3-13% of active agent, 0.2-1.5% of surface active agent, 0.2-3.0% of emulgator, 3.0-10.0% of thixotropic agent, 3-8% of film-forming agent, 0.1-1% of antioxidant, 0.1-0.5% of corrosion inhibitor and the rest of solvent. The active agent is composed of four or five components in succinic acid, oxalic acid, salicylic acid, glutaric acid, citric acid, adipic acid, lactic acid, benzoic acid, malic acid and triethanolamine. The scaling powder for the no-clean lead-free low silver welding paste does not contain halogen, the corrosion to a circuit board is greatly lowered, the printing quality of the welding paste is good without bridging or turned-down edges, a welding point is good in forming after returning, the brazing connecting defect is greatly lowered, the residue is small without solder balls, the cleaning is not needed, the welding paste is directly used for assembling, the Sn-0.45 Ag-0.68 Cu or Sn-0.3 Ag-0.7 Cu low silver welding paste manufactured by using the scaling powder does not contain the halogen and rosin, the organic chemistry smoke is small, and the pollution to the environment is small.
Owner:CHONGQING UNIV OF TECH

New Combination Dosage Form

InactiveUS20070122470A1Salicyclic acid active ingredientsBiocideGastrointestinal complicationsSalicylic acid
The present invention relates to an oral pharmaceutical preparation for use in the prevention and / or reduction of gastrointestinal complications associated with the use of acetyl salicylic acid. The present preparation comprises a fixed oral dosage form comprising a proton pump inhibitor in combination with acetyl salicylic acid. Furthermore, the present invention refers to a method for the manufacture thereof and the use thereof in medicine. The present invention also relates to a specific combination comprising esomeprazole, or an alkaline salt thereof or a hydrated form of any one of them, and acetyl salicylic acid for use as a medicament for the prevention of thromboembolic vascular events, such as myocardial infarction or stroke, and for the prevention and / or reduction of gastrointestinal complications associated with the use of acetyl salicylic acid.
Owner:ASTRAZENECA AB

Concomitant drug as therapeutic agent for inflammatory bowel disease

An object of the present invention is to provide a medicament efficacious for an inflammatory bowel disease such as ulcerative colitis or Crohn's disease. Specifically, it provides a therapeutic agent for inflammatory bowel diseases comprising active ingredient (a) consisting of at least one compound having inflammatory inhibiting activity selected from the group consisting of an aminosalicylic acid derivative, an antiinflammatory glucocorticoid, an immunosuppressive compound, an anti-TNFα antibody, a neurohypophysial hormone and an antiinfective compound, combined with active ingredient (b) consisting of at least one compound having PPARγ agonistic activity, wherein the agent is so configured that the compound (a) and the compound (b) are used simultaneously, separately or every scheduled time.
Owner:EISIA R&D MANAGEMENT CO LTD

Synergistically active mixture which inhibits hair growth

A process for inhibiting hair growth on skin comprising contacting the skin with a composition containing: (a) a hydrolyzed soya protein; (b) at least one plant extract selected from the group consisting of Hypericum perforatum, Hamamelis virginiana, Arnica montana, Salix alba, and mixtures thereof; and (c) optionally, an auxiliary component selected from the group consisting of urea, menthol, propylene glycol, salicylic acid, and mixtures thereof.
Owner:COGNIS FRANCE SA

Hair and scalp care formulations for treating and preventing acne and related skin conditions

InactiveUS20110256249A1Preventing and significantly reducing incidence of acneAggressive skin treatmentBiocideCosmetic preparationsSalicylic acidReducing agent
The present invention is directed to skin treatment formulations having salicylic acid and other secondary ingredients. The secondary ingredients may include: non-comedogenic essential oils and plant extracts and sebum reducing agents. Salicylic acid and the secondary ingredients are provided in amounts effective to provide a sufficiently aggressive skin treatment for unclogging pores and reducing inflammation, while maintaining levels of sebum on the exterior of the skin to form an operative water barrier on the skin and hair. Additionally, a method is provided that unclogs pores, reduces inflammation, and controls levels of sebum on the exterior of the skin to maintain an operative water barrier on the skin and hair. The method may include, applying a sufficiently aggressive product comprising salicylic acid, non-comedogenic plant extracts and essential oils, and a sebum reducing agent to hair and its surrounding areas.
Owner:CLEARSKIN RX INC

Nuisance-free medical fertilizers for prevention and curing of nematode and underground pest and production process thereof

InactiveCN101139234AEfficient fertilizerOvercome the disadvantages of poor efficacyBiocideNematocidesBiological StressPhoxim
The present invention discloses a non-social pollution drug fertilizer for preventing wireworm and underground pest and the relative technics process; the drug fertilizer consists of the following components according to the weight ratio: 1-10 percent of bitter bean, 1-10 percent of cattle heart Preserving Simplicity, 1-10 percent of azedarach fruit, 1-3 percent of carapace or chitosan, 0.5-2 percent of salicylic acid or natrium salicylicum, 1-3 percent of Chlopyrifos or phoxim, 1-5 percent of diffusing agent, 1-5 percent of surface active agent, 1-10 percent of adhesive agent, 5-15 percent of disintegrant, 5-20 percent of micro fertilizer, 10-50 percent of corrupted acid; wherein, the weight ratio of all components is 100 percent. The drug fertilizer in the present invention integrates nutrient, improving soil and preventing pest together, which has much better immunity, prevention and curing effect to the wireworm and underground pest. The present invention can realize the purpose for ''detoxification to the soil and epidemic prevention to the crops'', decrease the use quantity for fertilizer and venomous pesticide and enhance the biological stress for the soil and crops. The present invention does not leave in the crop and pollute the environment. The present invention can accelerate the growth for the crops, decrease the pests in the crops, increase the output and improve the quality.
Owner:淮安市农业科学研究院

Preparation process of herbicide dicamba

The invention relates to a preparation process of herbicide dicamba, in particular to a supercritical preparation process. The preparation process of the herbicide dicamba comprises the following steps of: preparing 2,5-dichlorophenol into corresponding sodium phenolate, and then completing carboxylation reaction under a supercritical condition to obtain 3,6-dichlorosalicylic acid; and then completing O-methylation to prepare a product of 3,6-dichloro-2-methoxy salicylic acid, i.e. the dicamba, by taking dimethyl carbonate as a reagent. The invention changes the heterogeneous gas-solid reaction of the traditional process into homogeneous reaction under the supercritical condition, carries out the O-methylation reaction by using the dimethyl carbonate and has the advantages of high reaction yield, good product quality, reduced environmental pollution, lowered energy consumption, and the like.
Owner:上海力智生化科技有限公司
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