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1906 results about "Propionates" patented technology

Derivatives of propionic acid. Included under this heading are a broad variety of acid forms, salts, esters, and amides that contain the carboxyethane structure.

Gene products of bacillus licheniformis which form odorous substances and improved biotechnological production methods based thereon

The present invention relates to 25 hitherto undescribed genes of B. licheniformis and gene products derived therefrom and all sufficiently homologous nucleic acids and proteins thereof. They occur in five different metabolic pathways for the formation of odorous substances. The metabolic pathways in question are for the synthesis of: 1) isovalerian acid (as part of the catabolism of leucine), 2) 2-methylbutyric acid and/or isobutyric acid (as part of the catabolism of valine and/or isoleucine), 3) butanol and/or butyric acid (as part of the metabolism of butyric acid), 4) propyl acid (as part of the metabolism of propionate) and/or 5) cadaverine and/or putrescine (as parts of the catabolism of lysine and/or arginine). The identification of these genes allows biotechnological production methods to be developed that are improved to the extent that, to assist these nucleic acids, the formation of the odorous substances synthesized via these metabolic pathways can be reduced by deactivating the corresponding genes in the micro-organism used for the biotechnological production. In addition, these gene products are thus available for preparing reactions or for methods according to their respective biochemical properties.
Owner:BASF AG

Melamine-formaldehyde microcapsule slurries for fabric article freshening

Described is a method for freshening fabric articles by means of spraying the articles with an aqueous slurry of microcapsules having rupturable melamine-formaldehyde polymeric walls, containing substantive and efficacious functional substances, e.g., malodour counteractants and/or fragrances. The slurry may optionally contain non-confined functional substances, e.g. malodour counteractants and/or fragrances. The method is effective for the deposition of effectively-rupturable malodour suppressant and/or fragrance emitting microcapsules onto fabrics wherein the resulting emitted fragrance activity and/or malodour counteractant activity is long-lasting and where the resulting substantive aroma is aesthetically pleasing over the long period of time for which it is effective. Also described are efficacious and substantive malodour counteractant compositions useful for the aforementioned process containing a malodour composition composed of zinc ricinoleate and at least one of: 1-cyclohexylethan-1-yl butyrate; 1-cyclohexylethan-1-yl acetate; 1-cyclohexylethan-1-ol; 1-(4′-methylethyl)cyclohexylethan-1-yl propionate; and/or 2′-hydroxy-1′-ethyl(2-phenoxy)acetate. In addition, described are efficacious microcapsule slurries useful for the aforementioned process containing microcapsules having melamine-formaldehyde polymeric capsule walls with the microcapsules being in contact with one or more polymeric silicone phospholipids.
Owner:INTERNATIONAL FLAVORS & FRAGRANCES

Methods of preparation and using antimicrobial products

Novel antimicrobial products and methods of making and using the same are shown, whereby the products can be used in the same or greater percentages as conventional microbial growth inhibitors without imparting an off-flavor, taste, color or odor to the products in which they are used. The antimicrobial products are formed by reacting azodicarbonamide or an ammonia gas with a compound selected from the group consisting of benzoic acid, sodium benzoate, calcium benzoate, potassium benzoate, acetic acid, sodium diacetate, paraben, niacin, calcium acetate, calcium diacetate, citric acid, lactic acid, fumaric acid, sorbic acid, sodium sorbate, calcium sorbate, potassium sorbate, propionic acid, sodium propionate, calcium propionate, potassium propionate and mixtures thereof. In one embodiment, the product is prepared by placing a layer of azodicarbonamide on a substrate and covering the layer with a gas permeable separator. The antimicrobial compound is then added on top of the separator, and the combination is heated to form the final product. In another embodiment, the product is prepared by exposing the antimicrobial compound to an ammonia gas. The ammonia gas reacts with free acids in the antimicrobial compound to convert the free acids into ammonium salts, thereby eliminating off-flavor and off-odor of the resulting antimicrobial product. The antimicrobial products prepared according to the present invention are suitable for use in foodstuffs, sanitation products, cosmetics, pharmaceuticals, and so forth.
Owner:TILLIN

Controlled release composition

InactiveUS20080254124A1Easy for to follow prescribed regimenConstant of releasePowder deliverySolution deliveryEthyl(hydroxyethyl)celluloseCellulose acetate
A composition for controlled delivery of at least one active substance into an aqueous medium by erosion at a preprogrammed rate of at least one surface of the composition, comprising a matrix comprising the active substance, the matrix being erodible in the aqueous medium in which the composition is to be used, and a coating having at least one opening exposing at least one surface of said matrix, the coating comprising a first cellulose derivative which has thermoplastic properties and which is substantially insoluble in the aqueous medium in which the composition is to be used, and at least one of a second cellulose derivative which is soluble or dispersible in water, a plasticizer, and a filler. The coating is a coating which crumbles and / or erodes upon exposure to the aqueous medium such as a body fluid. The first cellulose derivative may be, e.g., ethylcellulose, cellulose acetate, cellulose propionate or cellulose nitrate, and the second cellulose derivative may be, e.g. methylcellulose, carboxymethylcellulose or salts thereof, cellulose acetate phthalate, microcrystalline cellulose, ethylhydroxyethylcellulose, ethylmethylcellulose, hydroxyethylcellulose, hydroxyethylmethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, hydroxymethylcellulose or hydroxymethylpropylcellulose.
Owner:EGALET LTD

Preparation method of 3,5-dibenzoyl-2-deoxy-2-fluoro-2-methyl-D-ribo-gamma-lactone

The invention provides a preparation method of 3,5-dibenzoyl-2-deoxy-2-fluoro-2-methyl-D-ribo-gamma-lactone (sofosbuvir). The method comprises the following steps: adding alkali into a mixed solution of L-alanine isopropyl ester or an acid salt thereof and phenyl dichlorophosphate for reacting to obtain (S)-2-phenoxy-chloro-phosphoryl amino isopropyl propionate, reacting the (S)-2-phenoxy-chloro-phosphoryl amino isopropyl propionate with 4-trifluoromethylphenol in the presence of alkali at the temperature of 0-10 DEG C to obtain racemic (S)-2-[(4-trifluoromethyl-phenoxyl)-phenoxy-phosphoryl amino)]alanine isopropyl ester, dissolving the racemic (S)-2-[(4-trifluoromethyl-phenoxyl)-phenoxy-phosphoryl amino)]alanine isopropyl ester into an ether or alkane solvent at the normal temperature, cooling to 50-10 DEG C below zero, and separating (S)-2-[(S)-(4-trifluoromethyl-phenoxy)]-phenoxy-phosphoryl amino)]alanine isopropyl ester out; and reacting the (S)-2-[(S)-(4-trifluoromethyl-phenoxy)]-phenoxy-phosphoryl amino)]alanine isopropyl ester with (2'R)-2'-deoxy-2'-fluoro-2'-methyluridine in the presence of organic alkali with high steric hindrance to obtain the 3,5-dibenzoyl-2-deoxy-2-fluoro-2-methyl-D-ribo-gamma-lactone. The method has the advantages of simple steps, mild reaction and suitability for industrial production.
Owner:苏州东南药业股份有限公司
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