56 results about "Paraben" patented technology

The invention provides a teak camel moth artificial feeding feed and a teak camel moth artificial feeding method, the feed comprises the following components by weight: 8% of wheat germ powder, 4% of soybean meal, 4% of yeast powder, 2% of casein, 2% of sucrose, 1.8% of agar powder, 1.5% of cellulose, 0.8% of Webster salt, 0.6% of vitamin C, 0.2% of sorbic acid, 0.3% of methyl p-hydroxybenzoate, 0.1% of cholesterol, 0.1% of choline chloride, 0.05% of inositol, 0.01% of folic acid, and the balance of water. And the balance of deionized water. The invention further provides an artificial feeding method of teak camelmoths, and the artificial feeding method comprises the steps of 1, adult mating and egg laying, 2, egg disinfection and incubation and 3, larva rearing. The feed does not contain host material teak leaves, and full-artificial continuous large-scale feeding of the teak camelmoths can be achieved.

The present disclosure concerns radiopharmaceutical compositions of radioactive halogenated benzylguanidine (such as radioiodinated MIBG) or a pharmaceutically acceptable salt, hydrate, or solvate thereof. In a preferred embodiment, the composition has at least 97% of radiochemical purity for at least 4 days. Advantageously, the compositions of the present disclosure may be devoid of parabens, which are carcinogenic and yet are used in known radioactive MIBG compositions. The present disclosure also provides processes of preparing a radioactive halogenated benzylguanidine composition. The compositions of the present disclosure can be used in diagnosis and treatment of various diseases.

The invention discloses a preparation method of a predatory mite feed and a predatory mite feeding method. The predatory mite feed comprises a basic artificial feed and biomass, the basic artificial feed comprises egg yolk liquid, yeast extract powder, cane sugar, honey, purified water, peptone, potassium sorbate and p-hydroxybenzoate; the preparation method comprises the following steps: fully mixing the components into a semi-fluid mixture, and freeze-drying the semi-fluid mixture into a solid state at low temperature by using an instantaneous low-temperature freeze-drying technology to obtain the predatory mite feed. The predatory mite freeze-dried feed is prepared to be used for feeding predatory mites, a traditional feeding scheme of plants-pest mites-predatory mites can be replaced, the whole feeding process is simple, conditions are controllable and easy to control, and the feeding difficulty and the feeding cost are effectively reduced; meanwhile, the predatory mite feed is prepared into a freeze-dried state, the feed utilization rate can be increased, the predatory mites can easily eat the feed, and therefore the breeding efficiency of the predatory mites is improved.

A cooling sheet comprising: a backing layer; an adhesive agent layer; and a liner layer for protecting the adhesive agent layer, wherein the adhesive agent layer containswater at 65 to 85% by mass based on a total mass of the adhesive agent layer,polyalkylene glycol monooleate at 0.12 to 0.7% by mass based on the total mass of the adhesive agent layer,polyvinyl alcohol at 3 to 10% by mass based on the total mass of the adhesive agent layer,polyacrylic acid at 0.5 to 5% by mass based on the total mass of the adhesive agent layer, anda parahydroxybenzoate at 0.01 to 1% by mass based on the total mass of the adhesive agent layer, anda mass ratio of a content of the polyvinyl alcohol to a content of the polyacrylic acid is in a range of 1.2:1 to 5:1.

The disclosure relates to methods for amplifying a target nucleic acid. The methods include performing an amplifying step comprising contacting the nucleic acid with a polymerase, dNTPs, one or more set of primers specific for the nucleic acid, and an amplification enhancer that is methyl paraben or a derivative thereof. Also described are kits and reaction mixtures for the amplification of a target nucleic acid in the presence of the amplification enhancer, as well as methods for enhancing nucleic acid amplification.

The present disclosure provides an oral liquid composition comprising potassium chloride, free of alcohol, free of parabens, and with enhanced stability. The present disclosure further provides methods of using the oral liquid compositions comprising potassium chloride, and which are free of alcohol and parabens, for the treatment of hypokalemia in patients with or without metabolic alkalosis.

The invention provides a preparation method and application of a nipagin ester modified waterborne polyurethane emulsion. According to the invention, the paraben is taken as a modifier, the polyurethane emulsion synthesized by an acetone method shows excellent antibacterial performance when being applied to antibacterial fabric finishing, and the mechanical performance of the fabric is improved.

The utility model relates to the technical field of dibenzoxepinone heterocyclic derivatives, and discloses a preparation device of a dibenzoxepinone heterocyclic derivative. Comprising a base, a supporting rod is fixedly connected to the upper surface of the base, a preparation tank is fixedly connected to the end, away from the base, of the supporting rod, a feeding pipe is fixedly connected to the upper surface of the preparation tank, a discharging pipe is fixedly connected to the lower surface of the preparation tank, and a control valve is fixedly connected to the side surface of the discharging pipe. The upper surface of the base is fixedly connected with an extraction box, the extraction box is internally provided with a concentric-square-shaped pipe group, and the bent top end of the concentric-square-shaped pipe group is fixedly connected with a sealing seat. And water vapor is separated and discharged in the process of extracting the dibenzoxepinone heterocyclic derivative mixed solution, so that the extraction purity of the dibenzoxepinone heterocyclic derivative is improved.

The subject matter of the present invention is a novel composition in emulsion form comprising glycerol, vaseline, and liquid paraffin as well as a particular system of preservatives and gelling agents, wherein said composition is characterised by the absence of parabens.

Provided herein are substantially crystalline solid forms of 2-[3-[4-amino-3-(2-fluoro-4-phenoxy-phenyl)pyrazolo[3,4-d]pyrimidin-1-yl]piperidine-1-carbonyl]-4-methyl-4-[4-(oxetan-3-yl)piperazin-1-yl]pen-t-2-enenitrile (identified herein as Compound (I), and also known as PRN 1008 or rilzabrutinib) as a pharmaceutically-acceptable salt selected from an HCI, oxalate, and / or a maleate salt or alternatively, as a pharmaceutically-acceptable methyl paraben co-crystal, and pharmaceutical compositions comprising the substantially crystalline forms.

Compositions, products, systems, kits, and methods of perming hair may include a first-product (perming lotion) that contains cysteamine and cysteine, such that the first-product is used to break preexisting disulfide bonds in hair, and then a second-product may be applied directly over (on top of) the first-product to neutralize the effects of the first-product without first rinsing the hair to remove the first-product, so that disulfide bonds in the hair may form to set the treated hair into a desired shape with desired curls, waves, texture, and / or style. Various on-the-rod, off-the-rod, and / or perm tools may be used to maintain the hair in the desired shape until the first-product and the second-product have finished acting on the hair and / or on each other. The Compositions, products, systems, kits, and methods of perming hair are vegan, cruelty free, paraben free, sulfate surfactant free, use minimal water, and are without thioglycolic acid.

Disclosed is a thickener dispersion including a thickener including at least one among carboxymethyl cellulose and metal salt of the carboxymethyl cellulose, a change-over-time inhibitor, and an aqueous solvent. The change-over-time inhibitor includes at least one selected from the group consisting of phenoxyethanol, sodium azide, paraben, formaldehyde, 5-chloro-2-methyl-4-isothiazolin-3-one, sodium benzoate, ethylhexylglycerin, and 1,2-hexanediol. The thickener is included in an amount of 0.05 wt % to 3.5 wt % in the thickener dispersion, and the change-over-time inhibitor is included in an amount of 0.05 wt % to 3.0 wt % in the thickener dispersion.

To provide a dispersion liquid containing a paraben, which ensures excellent dispersion of the paraben in water and is capable of maintaining a dispersed state over an extended period of time.SOLUTION: The present invention relates to a dispersion liquid containing: a component (A), a benzyl 4-hydroxybenzoate represented by formula (1) or a salt thereof in an amount of 0.0001-70 mass%; a component (B), a surfactant having an aromatic group in an amount of 0.0001-10 mass%; and water, wherein the average particle diameter of the component (A) is 0.01-20 μm.SELECTED DRAWING: None

The present invention provides a toad oil cream and a preparation method thereof, and relates to the field of medical technology. The cream comprises toad oil and a matrix, wherein the toad oil is prepared according to the method of Chinese invention patent application CN117126696 A, and the matrix comprises phase A, phase B and phase C, wherein the phase A comprises: cetostearyl alcohol, glyceryl monostearate, liquid paraffin, dimethyl silicone oil and propylparaben, the phase B comprises: carbomer, glycerol, potassium lauryl phosphate, hyaluronic acid, methylparaben and water, and the phase C comprises the component triethanolamine. By optimizing the matrix, the cream obtained by the present invention has moderate hardness and softness, low cost, good coating property, uniformity and stability, and at the same time, the toad oil is turned into treasure.

The present invention provides a thickener dispersion liquid comprising: a thickener comprising at least one selected from the group consisting of carboxymethyl cellulose and a metal salt of the carboxymethyl cellulose; a time-dependent change inhibitor; and an aqueous solvent. The thickening agent dispersion liquid contains a thickening agent and a change over time inhibitor, the change over time inhibitor contains at least one selected from the group consisting of phenoxyethanol, sodium azide, paraben, formaldehyde, 5-chloro-2-methyl-4-isothiazolin-3-one, sodium benzoate, ethylhexylglycerin, and 1, 2-hexanediol, and the content of the thickening agent in the thickening agent dispersion liquid is 0.05 wt% to 3.5 wt%. And the content of the change over time inhibitor in the thickener dispersion liquid is 0.05 wt% to 3.0 wt%.

The present invention aims at the formulation and manufacture of a new natural shampoo without sulfates and without parabens based on laurel hydrosol which will purify the scalp, eliminate oils and combat the proliferation of bacteria. The shampoo composition provided by the invention contains the following components in mass percentage: 72% laurel hydrosol, 8.5% geranium hydrosol, 9% Sodium Lauroyl Sarcosinate surfactant, 8% Coco Betaine surfactant, 0.2% preservative, 0.7% thickening stabilizer Xanthan Gum, 1% laurel oil macerate and 0.5% laurel essential oil. The physicochemical analysis of the prepared shampoo shows that its pH is 6.90, its density is 0.91, and its foaming power is 210 ml. It is rheologically stable and does not cause skin irritation.

An additive comprising (i) a sugar oxidation product and (ii) a solvent. A personal care product comprising (i) an additive comprising (1) a sugar oxidation product and (2) at least one material selected from the group consisting essentially of a solvent, chelating agent, emollient, humectant, preservative and combinations thereof and (ii) at least one material selected from the group consisting essentially of an emollient, a preservative, a paraben, formaldehyde, a fragrance, an aldehyde, glycerin, a humectant, an emulsifier, citric acid, benzophenone, oxybenzone, zinc oxide, titanium dioxide, a surfactant, sodium lauryl sulfate, toluene, acetone, a solvent, sodium bicarbonate colorants, thickeners, stabilizers, preservatives, pH adjusters, pH buffers, silicones, natural extracts, antioxidants, thereof co-surfactants, conditioning agents, anti-dandruff agents, anti-microbial agents, suspending agents, pearlescent aids, foam boosters, pediculocides, proteins, vitamins, amino acids, skin active agents, sunscreens, UV absorbers, stabilizers, and combinations thereof.

The present invention relates to sustainable fast breaking W / O emulsions. The present invention relates to a cosmetic or dermatological composition, in particular to a cosmetic or dermatological composition free of silicon, paraben, mineral oil, PEG and polyacrylate, comprising an emulsifier complex of polyglycerol-3 polyricinoleate / polyglycerol-3 ricinoleate, and an oil phase comprising at least one non-polar oil and at least one polar oil, where IOBgt; the average weight of the oil having an IOB of 0 and the oil having an IOB of 0 is from 0.05: 1 to 12: 1 by weight, preferably from 1: 1 to 11: 1, preferably from 3: 1 to 5: 1, and the average IOB value of the total oil is from 0.2 to 0.5, preferably from 0.2 to 0.35. The emulsifier disclosed by the invention has good stability, acceptable sensory characteristics, good skin compatibility and good preservation performance.

The invention relates to the technical field of chemical catalysis, in particular to an efficient catalytic synthesis method of nipagin ester. According to the method, a supported heteropolyacid ionic liquid catalyst with UiO-66-NH2 as a carrier is adopted, ionic liquid and metal heteropolyacid salt are supported on the surface of epoxy group modified UiO-66-NH2 through specific steps, p-hydroxybenzoic acid and corresponding alcohol are used as raw materials, the catalyst accounting for 3%-5% of the mass of p-hydroxybenzoic acid is added under the specific substance amount ratio, and the reaction is carried out for 1-2 hours at the temperature of 50-60 DEG C to obtain the UiO-66-NH2 supported heteropolyacid ionic liquid catalyst. And the nipagin ester is synthesized, so that the yield is remarkably improved.

The present disclosure concerns radiopharmaceutical compositions of radioactive halogenated benzylguanidine (such as radioiodinated MIBG) or a pharmaceutically acceptable salt, hydrate, or solvate thereof. In a preferred embodiment, the composition has at least 97% of radiochemical purity for at least 4 days. Advantageously, the compositions of the present disclosure may be devoid of parabens, which are carcinogenic and yet are used in known radioactive MIBG compositions. The present disclosure also provides processes of preparing a radioactive halogenated benzylguanidine composition. The compositions of the present disclosure can be used in diagnosis and treatment of various diseases.

The present invention discloses an external traditional Chinese medicine compound ointment for treating radioactive dermatitis and a preparation method thereof. The ointment is composed of the following components in parts by weight: 1-40 parts of the extract of the stem and leaf of Gynura Root, 1-10 parts of the extract of Poria cocos, 1-15 parts of the extract of Coix lacryma-jobi, 1-10 parts of the extract of Forsythia suspensa, 1-15 parts of the extract of Atractylodes macrocephala, 0.1-0.5 part of paraben, 1-500 parts of petrolatum, 1-2 parts of β-sitosterol, 1-5 parts of zinc oxide powder, 1-2 parts of talcum powder, 1-2 parts of sodium stearate, and 1-20 parts of ethanol. The traditional Chinese medicine of the present invention adopts traditional Chinese medicine extracts, which maximally reduces the residues of pesticides and heavy metals, improves the solubility, and makes the medicine more easily absorbed by the skin. The external traditional Chinese medicine compound ointment of the present invention can effectively treat radioactive dermatitis, with good effect, quick onset, and low cost. After the patients use it, the related adverse manifestations of radioactive dermatitis significantly subside.

The present invention addresses the problem of providing a hot melt adhesive which does not undergo phase separation even if the adhesive is heated for a long time, is highly safe for humans, and exhibits stable anti-bacterial properties that can be maintained even if the adhesive is heated for a long time. The problem can be solved by a hot melt adhesive which contains a base polymer, a tackifier and an antimicrobial agent which has a paraben structure and has a 10% weight loss temperature of 200°C or higher in thermogravimetric measurements. The hot melt adhesive has a melt viscosity at 140ºC of 20,000 mPa·s or less.

The invention belongs to the technical field of pigment red preparation, and particularly provides a high crystal transformation quality-based quinacridone pigment red surface treatment process, which comprises the following steps: 1) taking a pigment crude product, and carrying out grinding and salt milling to obtain a primary treatment material; and 2) adding a solvent and a MA-HBA derivative into the primary treatment material, stirring for pigmentation, and then filtering and drying to obtain the pigment red, the MA-HBA derivative is prepared by synthesizing methyl p-hydroxybenzoate and 1, 11-undecanediol, and the prepared pigment red has the advantages of good pigmentation effect and good covering power.

Fexofenadine zwitterionic dihydrate form I of formula (I) Paraben-free aqueous pharmaceutical suspension formulations and uses thereof are provided, including JPEG2026501487000031.jpg4390. In certain embodiments, the formulations include polypropylene glycol, edetate disodium, potassium sorbate, xanthan gum, poloxamer 407, titanium dioxide, sodium phosphate monobasic monohydrate, sodium phosphate dibasic heptahydrate, artificial raspberry cream flavor, sucrose, xylitol, and purified water. The disclosure also includes methods of making such formulations.

This fluorescent inspection liquid is obtained by dissolving, in water, a composition that contains: a fluorochrome that is easily broken down by microorganisms, light or oxygen; and a preservative that prevents putrefaction of the fluorochrome. The preservative contains a parahydroxybenzoic acid ester or an isothiazolinone derivative.

The invention relates to a method for preparing a covalent organic framework adsorbent and extracting and detecting paraben, and belongs to the technical field of adsorption materials. The preparation method comprises the following steps: dispersing Fe3O4 nanoparticles and an amino organic monomer containing ureido in an organic solvent, adding an aldehyde group organic monomer, sequentially carrying out primary ultrasonic operation, vortex operation and secondary ultrasonic operation, standing and reacting at room temperature for 1-1.5 hours, and carrying out magnetic separation to obtain a crude product; washing the crude product with N, N-dimethylformamide and ethanol in sequence; and drying the obtained product in vacuum to obtain the magnetic ureido covalent organic framework adsorbent. The adsorbent provides a hydrogen bond and pi-pi accumulation effect, and can perform high-selectivity extraction and detection on p-hydroxybenzoate in samples such as toning lotion and the like.

An immediate-release liquid oral suspension of Eslicarbazepine Acetate, containing between about 5 to about 10 g of active ingredient per 100 mL, along with carbomer homopolymer and microcrystalline cellulose as viscosity modifying agents. It may further comprise, parabens as antimicrobial agent, sucralose as a sweetener, and polyethylene glycol 8 stearate as a surfactant. The suspension is designed to provide bioequivalence to marketed Eslicarbazepine Acetate tablets, ensuring rapid drug release and stability over extended storage periods. The pH is adjusted to 3.0-6.5 to maintain stability, with impurities remaining under 0.05% of the eslicarbazepine content after stress storage conditions. This formulation offers an alternative to solid dosage forms for patients with partial-onset seizures.

Provided is a paraben-free aqueous pharmaceutical suspension formulation comprising fexofenadine zwitterionic dihydrate Form I of formula (I)and uses thereof. In certain embodiments, the formulation comprises polypropylene glycol, edetate disodium, potassium sorbate, xanthan gum, poloxamer 407, titanium dioxide, sodium phosphate monobasic monohydrate, sodium phosphate dibasic heptahydrate, artificial raspberry cream flavor, sucrose, xylitol, and purified water. The disclosure also includes methods of making such formulations.

This disclosure relates to deodorizing compositions, ostomy devices, and uses thereof. In certain embodiments, the disclosure contemplates a deodorizer comprising a combination of citric acid and a citric acid salt, cocamidopropyl betaine, zinc ricinoleate, and optionally comprising a preservative such as a paraben. In certain embodiments, the deodorizing composition is contained loaded in a hydrogel or hydrophilic polyurethane. In further embodiments, the loaded hydrogel or hydrophilic polyurethane is placed in an ostomy device.

The invention discloses a butylparaben cation salt derivative, the structural general formula of which is shown as a formula P. In the formula, R is selected from C1-C12 straight chain or branched chain alkyl with substituent groups, five-membered or six-membered cycloalkyl or aryl with substituent groups, and the C1-C12 straight chain or branched chain alkyl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent groups, the C1-C12 straight chain or branched chain alkyl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent the substituent group in the five-membered or six-membered naphthenic base or aryl with the substituent group is at least one of hydrogen, halogen and C1-C6 alkyl; a is selected from-CO <-> or-CH2 <->; q is selected from nitrogen or phosphine; x is selected from chlorine or bromine; n is equal to 0-10. According to the invention, the antibacterial property and antibacterial spectrum of the butylparaben are improved, and the butylparaben has the advantages of rapid sterilization and long-acting sterilization, and also has efficient and broad-spectrum sterilization effects.