11 results about "Paraben" patented technology

The present disclosure provides an oral liquid composition comprising potassium chloride, free of alcohol, free of parabens, and with enhanced stability. The present disclosure further provides methods of using the oral liquid compositions comprising potassium chloride, and which are free of alcohol and parabens, for the treatment of hypokalemia in patients with or without metabolic alkalosis.

Disclosed is a thickener dispersion including a thickener including at least one among carboxymethyl cellulose and metal salt of the carboxymethyl cellulose, a change-over-time inhibitor, and an aqueous solvent. The change-over-time inhibitor includes at least one selected from the group consisting of phenoxyethanol, sodium azide, paraben, formaldehyde, 5-chloro-2-methyl-4-isothiazolin-3-one, sodium benzoate, ethylhexylglycerin, and 1,2-hexanediol. The thickener is included in an amount of 0.05 wt % to 3.5 wt % in the thickener dispersion, and the change-over-time inhibitor is included in an amount of 0.05 wt % to 3.0 wt % in the thickener dispersion.

The present invention aims at the formulation and manufacture of a new natural shampoo without sulfates and without parabens based on laurel hydrosol which will purify the scalp, eliminate oils and combat the proliferation of bacteria. The shampoo composition provided by the invention contains the following components in mass percentage: 72% laurel hydrosol, 8.5% geranium hydrosol, 9% Sodium Lauroyl Sarcosinate surfactant, 8% Coco Betaine surfactant, 0.2% preservative, 0.7% thickening stabilizer Xanthan Gum, 1% laurel oil macerate and 0.5% laurel essential oil. The physicochemical analysis of the prepared shampoo shows that its pH is 6.90, its density is 0.91, and its foaming power is 210 ml. It is rheologically stable and does not cause skin irritation.

The invention belongs to the technical field of pigment red preparation, and particularly provides a high crystal transformation quality-based quinacridone pigment red surface treatment process, which comprises the following steps: 1) taking a pigment crude product, and carrying out grinding and salt milling to obtain a primary treatment material; and 2) adding a solvent and a MA-HBA derivative into the primary treatment material, stirring for pigmentation, and then filtering and drying to obtain the pigment red, the MA-HBA derivative is prepared by synthesizing methyl p-hydroxybenzoate and 1, 11-undecanediol, and the prepared pigment red has the advantages of good pigmentation effect and good covering power.

An immediate-release liquid oral suspension of Eslicarbazepine Acetate, containing between about 5 to about 10 g of active ingredient per 100 mL, along with carbomer homopolymer and microcrystalline cellulose as viscosity modifying agents. It may further comprise, parabens as antimicrobial agent, sucralose as a sweetener, and polyethylene glycol 8 stearate as a surfactant. The suspension is designed to provide bioequivalence to marketed Eslicarbazepine Acetate tablets, ensuring rapid drug release and stability over extended storage periods. The pH is adjusted to 3.0-6.5 to maintain stability, with impurities remaining under 0.05% of the eslicarbazepine content after stress storage conditions. This formulation offers an alternative to solid dosage forms for patients with partial-onset seizures.

Provided is a paraben-free aqueous pharmaceutical suspension formulation comprising fexofenadine zwitterionic dihydrate Form I of formula (I)and uses thereof. In certain embodiments, the formulation comprises polypropylene glycol, edetate disodium, potassium sorbate, xanthan gum, poloxamer 407, titanium dioxide, sodium phosphate monobasic monohydrate, sodium phosphate dibasic heptahydrate, artificial raspberry cream flavor, sucrose, xylitol, and purified water. The disclosure also includes methods of making such formulations.

The invention discloses a butylparaben cation salt derivative, the structural general formula of which is shown as a formula P. In the formula, R is selected from C1-C12 straight chain or branched chain alkyl with substituent groups, five-membered or six-membered cycloalkyl or aryl with substituent groups, and the C1-C12 straight chain or branched chain alkyl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent groups, the C1-C12 straight chain or branched chain alkyl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent groups, the five-membered or six-membered cycloalkyl or aryl with substituent the substituent group in the five-membered or six-membered naphthenic base or aryl with the substituent group is at least one of hydrogen, halogen and C1-C6 alkyl; a is selected from-CO <-> or-CH2 <->; q is selected from nitrogen or phosphine; x is selected from chlorine or bromine; n is equal to 0-10. According to the invention, the antibacterial property and antibacterial spectrum of the butylparaben are improved, and the butylparaben has the advantages of rapid sterilization and long-acting sterilization, and also has efficient and broad-spectrum sterilization effects.

This invention relates to a gel preparation with pistachio shell extract as the active ingredient which has the effect of inhibiting Staphylococcus aureus bacteria. The gel consists of pistachio shell extract made from a maceration process using 70% alcohol, 5% CMC-Na gel base, 5.0% glycerin humectant, 3.0% propylene glycol, 0.25% methyl paraben preservative and aquades solvent added up to 100%. The gel has antibacterial activity which is characterized by the formation of an inhibition zone against Staphylococcus aureus bacteria. The emergence of this inhibition zone is due to the active compound contained in the gel base diffusing through the media so that it is able to inhibit the growth of Staphylococcus aureus bacteria. The positive control used in this antibacterial test is 1.2% clindamycin phosphate gel.From the results of the antibacterial effectiveness test that has been carried out, it was found that 10% to 25% pistachio shell extract gel can inhibit ≥15mm-24mm of Staphylococcus aureus bacterial growth with Minimum Inhibitory Concentration (MIC) and Minimum Bactericidal Concentration (MBC) values ​​of 80% and 100%, respectively.

A hair cleansing composition, comprising: i) 0.2 to 2.5 wt %, preferably from 0.5 to 2 wt %, of a glutamate salt, preferably sodium glutamate, most preferably monosodium glutamate; and ii) a cleansing surfactant; wherein the pH is in the range of from 4.1 to 6, preferably 4.1 to less than 5; and wherein the composition is free from parabens.

The invention relates to the technical field of traditional Chinese medicine gel preparation, in particular to asiaticoside gel and a preparation method and application thereof. The asiaticoside gel is used for preparing a preparation for wound healing and comprises the following components in parts by weight: 0.2-2 parts of an asiaticoside extract or lipidosome with the content of total asiaticoside in an active ingredient being 70-80wt%, 0.2-2 parts of a p-hydroxybenzoate compound, 2-10 parts of glycerol and 5-20 parts of carbomer. The preparation method comprises the following steps: S1, swelling carbomer, and adjusting the pH value to obtain carbomer gel; s2, dissolving the asiaticoside extract or lipidosome and a p-hydroxybenzoate compound into glycerol to obtain a glycerol solution; and S3, adding a glycerol solution into the carbomer gel, and uniformly stirring to obtain the asiaticoside gel. The asiaticoside gel prepared by the invention has the advantages of no toxic or side effect, freshness, transparency, no greasiness and good wound healing effect in the wound healing process.

An objective is to provide an antibacterial hot-melt adhesive that does not undergo phase separation even when heated for a long time, has high safety for the human body, and is able to maintain stable antibacterial properties even when heated for a long time. The objective is achieved by a hot-melt adhesive that includes: a base polymer; a adhesive; and an antibacterial agent that has a paraben structure and that has a 10% weight loss temperature of not lower than 200°C in thermogravimetric measurement, the hot-melt adhesive having a melting viscosity at 140°C of not greater than 20,000 mPa·s.