1962 results about "Hydroxybenzoic acid" patented technology

This invention provides methods and devices for spatially separating at least first and second components in a sample which in one exemplary embodiment comprises introducing the first and second components into a first microfluidic channel of a microfluidic device in a carrier fluid comprising a spacer electrolyte solution and stacking the first and second components by isotachophoresis between a leading electrolyte solution and a trailing electrolyte solution, wherein the spacer electrolyte solution comprises ions which have an intermediate mobility in an electric field between the mobility of the ions present in the leading and trailing electrolyte solutions and wherein the spacer electrolyte solution comprises at least one of the following spacer ions MOPS, MES, Nonanoic acid, D-Glucuronic acid, Acetylsalicyclic acid, 4-Ethoxybenzoic acid, Glutaric acid, 3-Phenylpropionic acid, Phenoxyacetic acid, Cysteine, hippuric acid, p-hydroxyphenylacetic acid, isopropylmalonic acid, itaconic acid, citraconic acid, 3,5-dimethylbenzoic acid, 2,3-dimethylbenzoic acid, p-hydroxycinnamic acid, and 5-br-2,4-dihydroxybenzoic acid, and wherein the first component comprises a DNA-antibody conjugate and the second component comprises a complex of the DNA-antibody conjugate and an analyte.

Trunk piston marine engine lubrication, when the engine is fueled by heavy fuel oil, is effected by a composition comprising a major amount of an oil of lubricating viscosity containing at least 50 mass % of a basestock containing greater than or equal to 90% saturates and less than or equal to 0.03% sulphur or a mixture thereof, and respective minor amounts of an over-based metal hydrocarbyl-substituted hydroxybenzoate detergent other than such a detergent having a basicity index of less than two and a degree of carbonation of 80% or greater and at least 1 mass % of a hydrocarbyl-substituted carboxylic acid, anhydride, ester or amide thereof. Asphaltene precipitation in the lubricant, caused by the presence of contaminant heavy fuel oil, is prevented or inhibited.

The invention relates to a dibenzoxazine containing an oxazole ring and a preparation method thereof. The preparation method comprises the following two steps of: 1: mixing ortho-aminophenol hydrochloride and para-hydroxybenzoic acid, adding polyphosphoric acid as a solvent, reacting at 60-180 DEG C for 24-60 hours, and washing by using deionized water, filtering and drying to obtain diphenol containing an oxazole ring structure; and 2: mixing the diphenol containing the oxazole ring structure, phenylamine and paraformaldehyde, reacting at 80-110 DEG C for 40-80 minutes, then filtering and precipitating, washing 4-8 times by using alkali liquor, and then washing, filtering and drying to obtain the product. The dibenzoxazine disclosed by the invention has the advantages of very good mechanical property because the high temperature resistant oxazole ring structure is introduced to a benzoxazine molecule structure, dielectric constant of only 1.6-2.3, simple process, lower equipment requirement and suitability for large-scale production.

The invention discloses a composition containing HFC-161 and a stabilizer, wherein the stabilizer is selected from one or more of epoxy compound, nitro-compound, hindered amines, hindered phenols, secondary arylamines, beta-diketones, phosphite esters, salicylic acid esters, cinnamic acid esters, hydroxybenzophenones, hydroxybenzoic acids, hydroxylphenyl benzotriazoles, hydroxylphenyl triazines, oxanilides, formamidines, polyhydric alcohols, ortho-formates, organosulfur compounds, olefins, ethanol amines and fatty amines. The composition provided by the invention is capable of keeping a stable state in a long time under the coexistence of air or oxygen, and capable of being used as a heat transfer composition in the form of a liquid or a gas, a refrigerant, an aerosol propellant and the like.

A process for preparing liquid crystal copolyester by solid polymerization includes such steps as heating the prepolymer poly(parahydroxy benzoic acid/2,6-naphthalenediformic acid/terephthalic acid/hydroquinone) to a temp which is 10-60 deg.c lower than its fusion point, and solid polimerizing reaction under existance of inertial gas.

The invention relates to an artificial feed of sesamia inferens walker as well as a preparation method and a feeding method thereof, belonging to the technical field of insect feeding. The artificial feed comprises soybean meal, corn meal, wheat germ, yeast powder, casein, cane sugar, honey, fresh wild rice shoots or fresh rice stems, ascorbic acid, cholesterol, choline chloride, Fiske salt, vitamin B complex, vitamin E, sorbic acid, methyl parahydroxybenzoats, 40 percent formaldehyde, 98.18 percent rice ketone, agal-agal and water. A long-term and successive feeding method of the sesamia inferens walker is carried out by adopting a wild rice shoots (young larva) and artificial feed (old larva until pupation). The fed larva of the sesamia inferens walker have development period of 24.8 days, larva survival rate of 76.6 percent, percentage of pupation of 87.7 percent, eclosion rate of 91.3 percent, egg laying amount of 101.9 for single adult and egg hatching rate of 88.8 percent. The invention has the advantages of low cost, practicability, simple preparation, and the like, and is suitable for massive, long-term and successive feeding of standard test sesamia inferens walkers.

The invention relates to high-level production of pHBA in green plants using a unique expression cassette. The latter comprises a chorismate pyruvate lyase (CPL) coding sequence operably linked to a suitable promoter capable of driving protein expression in higher plants. Additionally, the CPL cassette comprises a sequence encoding a chloroplast transit peptide, its natural cleavage site, and a small portion of the transit peptide donor protein fused to the N-terminus of CPL. The chloroplast targeting sequence targets the foreign protein to the chloroplast compartment and aids in its uptake into the organelle. The cleavage site is unique to the transit peptide, and cleavage of the chimeric protein encoded by the cassette at this site releases a novel polypeptide that has full enzyme activity, comprising the mature CPL enzyme and a small portion of the transit peptide donor.

A method of inhibiting skin darkening whilst inhibiting perspiration in the underarm which comprises incorporating into a antiperspirant composition comprising an astringent salt comprising an aluminium and/or zirconium salt, a triglyceride oil and optionally an active acid comprising an aliphatic dicarboxylic acid, especially C₆-C₁₂ such as azelaic acid, an unsaturated C₁₈ aliphatic carboxylic acid such as a linoleic acid or an hydroxybenzoic acid such as salicylic acid, at a ratio to said astringent salts, x:y, of 1:<4 in which x represents the weight concentration of said triglyceride oil plus 4 times the weight concentration of active carboxylic acid and y represents the weight concentration of said astringent salts. The composition can additionally comprise glycerol and/or a chelating agent for a transition metal.

The invention discloses a preparation method of a thermotropic liquid crystal polyarylester fiber, relates to a preparation method of thermotropic liquid crystal polyarylester, and aims to solve the problems that the existing method for preparing the thermotropic liquid crystal polyarylester is complex and the polyarylester fiber is low in tensile strength. The preparation method of the thermotropic liquid crystal polyarylester fiber comprises the following steps: step one, adding p-hydroxybenzonic acid, 2-(4-hydroxyphenyl)-5-carboxylbenzimidazole, acetic anhydride, 4-diethylaminopyridine and an antioxidant into a polymerization kettle for carrying out melt condensation polymerization to prepare a pre-polymer of thermotropic liquid crystal polyarylester; step two, putting the pre-polymer in a rotary kiln under the condition with nitrogen protection for carrying out solid phase polycondensation reaction to obtain high-molecular-weight polymer powder; step three, mixing the high-molecular-weight polymer powder, then cooling and drawing to prepare primary polyarylester fiber; and step four, carrying out heat treatment on the primary polyarylester fiber. The preparation method of the thermotropic liquid crystal polyarylester fiber is simple to operate; the tensile strength of the polyarylester fiber which is finally obtained can reach 4.0-4.5GPa.

Discussed herein are pharmaceutical compositions containing Ibrutinib and processes for preparing them. The compositions may be utilized in the treatment of a variety of conditions including, without limitation, B-cell proliferative disorders such as non-Hodgkin lymphoma (diffuse large B cell lymphoma, follicular lymphoma, mantle cell lymphoma or burkitt lymphoma), Waldenstrom macroglobulinemia, plasma cell myeloma, chronic lymphocytic leukemia, lymphoma, or leukemia. These compositions are designed for oral ingestion. The compositions are contained within a capsule such as a standard or sprinkle or in a liquid formulation such as a suspension. In one embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, and magnesium stearate. In another embodiment, the pharmaceutical composition contains Ibrutinib, a salt, prodrug, or metabolite thereof, microcrystalline cellulose, carboxymethylcellulose sodium, hydroxypropylmethylcellulose, citric acid monohydrate, disodium hydrogen phosphate, sucralose, sodium methyl parahydroxybenzoate, sodium ethyl parahydroxybenzoate, concentrated hydrochloric acid, sodium hydroxide, and water.

New polymers and new anti-reflective compositions containing such polymers are provided. The compositions comprise a polymer (e.g., epoxy cresol novolac resins) bonded with a chromophore (4-hydroxybenzoic acid, trimellitic anhydride). The inventive compositions can be applied to substrates (e.g., silicon wafers) to form anti-reflective coating layers having high etch rates which minimize or prevent reflection during subsequent photoresist exposure and developing.

Patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, are treated by administering to a patient in need thereof compositions that are hydroxybenzoate salts of E-metanicotine-type compounds. The formation of hydroxybenzoate salts of the E-metanicotine compounds is also useful in purifying the E-metanicotine compounds, as the hydroxybenzoate salts tend to crystallize out, leaving impurities such as Z-metanicotine compounds, and compounds where the double bond has migrated, in solution. If desired, the hydroxybenzoate salts can be converted to either the free base (the E-metanicotine) or to another pharmaceutically acceptable salt form.

An antimicrobial composition containing a cationic polymer having limited antimicrobial activity (such as a hydrophobically-modified quaternary ammonium cellulose ether) and an antimicrobial compound (such as one or more compounds selected from the group consisting of diiodomethyl-para-tolylsulfone, ortho-phenylphenol, sodium pyrithione, zinc pyrithione, 3-iodo-2-propynylbutylcarbamate, 2-methyl-4-isothiazolin-3-one, 1,2-benzisothiazolin-3-one, 2-n-octyl-4-isothiazolin-3-one, 1-(3-chloroallyl)-3,5,7-triaza-1-azoniaadamantane chloride, 2-(4-thiazolyl)-benzimidazole, β-bromo-β-nitrostyrene, 2,4,4′-trichloro-2-hydroxyphenyl ether, chloroxylenol, chlorocresol, para-tert-amylphenol, N-(4-chlorophenyl)-N′-(3,4 dichlorophenyl)-urea, and para-hydroxybenzoic acid esters). The growth of microorganisms (such as Pseudomonas aeruginosa) can be inhibited by exposing the microorganism to such a composition.

The invention discloses a preparation method of 3,6-dichloro-2-hydroxybenzoic acid, which sequentially comprises the following steps: 1) salifying 2,5-dichlorophenol; 2) carboxylation: transferring the 2,5-dichlorophenate solution into a high-pressure reaction kettle, adding a cocatalyst, and introducing CO2 to carry out high-pressure carboxylation reaction to obtain the reaction product containing 3,6-dichloro-2-hydroxybenzoate, wherein the cocatalyst is composed of potassium carbonate and activated carbon; 3) refinement: after cooling the reaction product containing 3,6-dichloro-2-hydroxybenzoate obtained in the step 2) to room temperature, adding an alkali solution, regulating the pH value to 11-13, uniformly stirring, filtering to recover activated carbon, stratifying the filtrate, and taking the water phase; and adding an acid solution into the water phase, regulating the pH value to 1-3, carrying out vapor distillation to recover the 2,5-dichlorophenol, cooling to crystallize, carrying out vacuum filtration, and drying to obtain the 3,6-dichloro-2-hydroxybenzoic acid.

This invention relates to methods and materials to produce para-hydroxybenzoic acid in the stem tissue of transgenic green plants using a cellulose synthase promoter to operably express a gene encoding HCHL.

The invention relates to a composite for preservation of human saliva and a preparation method of the composite. The composite comprises the following components: Tris-HCl with pH being 6-8.5 (5-20mmol/L), EDTA (Ethylene Diamine Tetraacetic Acid) (0.5-2mmol/L), NaOAc (2.5-3.5mol/L), cane sugar (0.1-0.4mol/L), N-acetyl-5-methoxytryptamine (1-3mmol/L), propylparaben (1-4mg/mL), diazonium imidazolidinyl urea (1-3mg/mL), protease K(10mu g/mL) and a system with pH being 7.5-8.5. When used for preservation of human saliva, the composite is capable of inhibiting nuclease activity and preventing nuclease from being contaminated by external microbes or being oxidized by itself, thereby guaranteeing the integrality and the purity of genomic DNA (deoxyribonucleic acid). The composite is long in preservation period, wide in preservation temperature range and applicable to gene detection and related scientific researches.

The invention belongs to the technical field of a limestone-gypsum wet-method flue gas desulfuration process and relates to a multifunctional composite additive for a wet-method flue gas desulfuration process and a using method thereof. The composite additive comprises the following components in percentage by mass: 31 to 45 percent of nylon acid, 31 to 45 percent of sodium humate, 6 to 9 percentof organic silicon defoaming agent, 2 to 5 percent of potassium formate, 2 to 5 percent of manganese sulfate and 2 to 5 percent of p-hydroxybenzoic acid. The composite additive can promote the dissolution of the limestone and reduce the using amount of the limestone, has an enhancement factor for improving an absorption reaction of sulfur dioxide (SO2), accelerates the migration speed of SO2 gas liquid, promotes the adsorption reaction of the SO2 in a liquid membrane, inhibits the soft scales of calcium sulfate (CaSO3) from generating, improves the pH value buffer capacity of limestone slurry, slows down the reducing speed of the pH value in the process of absorbing the SO2 by the desulfuration slurry continuously, and achieves the effect of avoiding bubbling and overflow of the desulfuration slurry.

The invention provides a preparation method and application of an anti-soil polymer. The prepared polymer is used as a dispersant for a hydraulic cementing agent and/or an aqueous dispersion for potential hydraulic cementing agent and has good anti-soil performance. The preparation method the anti-soil polymer comprises a step of subjecting polyether macromonomer A with a special structure, monomer B containing a phosphoric acid or phosphorous acid group, optional monomer D and aldehyde C to condensation polymerization so as to prepare the anti-soil polymer, wherein the monomer D is selected from the group consisting of phenol, aniline, p-/o-aminobezene solfonic acid, p-/o-hydroxybenzoic acid, p-/o-aminobenzoic acid, p-/o-hydroxyezene solfonic acid, p-/o-toluidine and p-/o-methylphenol, a mol ratio of the polyether macromonomer A to the monomer B to the monomer D is 1: (0.5-12): (0-8.0), and a mol ratio of the polyether macromonomer A to the monomer B and the monomer D is 1: (0.5-12.0).

Disclosed is hair conditioning compositions comprising antidandruff agent wherein the hair conditioning composition is substantially free of the group selected from a chelating agent, methylchloroisothiazolinone, and methylisothiazolinone. The compositions comprise by weight: (a) from about 0.1 % to about 15 % of a high melting point fatty compound; (b) compounds selected of; (b1a) from about 0.1 % to about 10 % of an amidoamine having the following general formula: R<1> CONH (CH2)m N(R<2>)2 wherein R<1> is a residue of C11 to C24 fatty acids, R<2> is a C1 to C4 alkyl, and m is an integer from 1 to 4; (b1b) an acid selected from the group consisting of 1 glutamic acid, lactic acid, hydrochloric acid, malic acid, acetic acid, fumaric acid, 1 glutamic acid hydrochloride, tartaric acid, and mixtures thereof, at a level such that the mole ratio of amidoamine to acid is from about 1:0.3 to about 1:1; or (b2) the combination of; (b2a) from about 0.1% to about 10% of a cationic conditioning agent; and (b2b) from about 0.1% to about 10% of a low melting point oil having a melting point of less than 25 DEG C; (c) a safe and effective amount of an antidandruff agent; (e) a preservative system comprising, by weight of the entire composition, from about 0.1% to about 1.0% of benzyl alcohol, from about 0.1 % to about 1.0 % of phenoxy ethanol, from about 0.05 % to about 1.0 % of methyl paraben, and from about 0.05 % to about 1.0 % of mettryl paraben, and from about 0.01 % to about 1.0 % of propyl paraben; and (f) an aqueous carrier.

The invention discloses skin whitening, moisturizing and nourishing gel. Each 160 grams of the skin whitening, moisturizing and nourishing gel comprises the following materials by weight: 0.1-1.5 g of carbomer, 0.05-0.1 g of triethanolamine, 2-8 g of glycerol, 3-7 g of olive oil, 1-4 ml of 70% sorbitol,0.5-3.5 g of honey, 2-5 g of bletilla striata extract, 13-20 g of cucumber extract, 0.1-1 g of tween-80, 0.1-0.5 g of ethyl p-hydroxybenzoate, 1-3 ml of 95% ethanol, 0.05-0.25 ml of essence and 90-150 ml of distilled water. Compared with the prior art, the skin whitening, moisturizing and nourishing gel is glittering and translucent, has suitable viscosity and consistency, good stability and fragrant smell, can make the skin feel better and can be absorbed quickly.

Non-steroidal anti-infammatory after shave preparations to aid in the prevention and treatment of Pseudofolliculitis Barbae and a method of delivering the ingredients of the preparation to affected areas of the skin. Formula I comprises ethanol, salicylic acid, propylene glycol, glycerine, fragrance, at least one compound for reducing skin irritation and at least one non-steroidal anti-inflammatory agent wherein said non-steroidal anti-inflammatory agent is an NSAID drug, a naturally occurring herbal compound containing an anti-inflammatory component or combinations thereof. Formula 11 comprises water, hydrolyzed oat flour, sorbitol, methylparaben, petrolatum, lanolin, cetyl alcohol, sunflower seed oil, stearic acid, propylparaben, triethanoloamine, a preservative, and at least one non-steroidal anti-inflammatory agent wherein said non-steroidal anti-inflammatory agent is an NSAID drug, a naturally occurring herbal compound containing an anti-inflammatory component or combinations thereof. The formulas have sufficient viscosity to allow the after shave preparation to remain on an affected area of the skin for a sufficient period of time to optimize the skin irritation reduction and anti inflammatory effects on the affected area thus providing local relief from irritation due to PFB.

The invention discloses a humidifying piece and a humidifying mask with the same. The humidifying piece comprises moisturizing components, wherein the moisturizing components include one or multiple components of hyaluronic acid, hydroxyethyl cellulose, trimethyl glycine and ethyl p-hydroxybenzoate. Medical components can be selectively added into the humidifying piece and include mint, eucalyptus oil or natural borneol. The humidifying piece comprising the moisturizing components is placed in an interlayer of a mask body to provide moisture needed by nasal cavities of a human body, the humidity of the nasal cavities and an oral cavity is kept, medicines are continuously fed, nasal mucosa drying is avoided, and the humidifying mask is suitable for wearing in dry air environments or after various rhinitis or nasal operations.

The invention discloses a Pseudomonas aeruginosa strain TBPY, which is screened from tribromophenol(TBP)-polluted sludge and purified. The purified strain is domesticated by a pressure type domesticating method with gradually increased TBP concentration in an organic salt culture medium, and the domesticated strain can be used for the biological control of waste water containing persistent organic pollutants such as phenol, pyrocatechol, resorcinol, benzoic acid, p-hydroxybenzoic acid, vanillin, 4-chlorophenol, 2,4-dichlorophenol, trichlorophenol and tribromophenol and has high research and application values.