312 results about "Hydroxybenzoic acid" patented technology

The invention discloses streptomyces bulbus as well as a multifunctional fungicide and application thereof. According to the invention, firstly, a strain of Streptomyces tauricus zhanshen-LZ-12 is separated and screened from straw returning soil, and the preservation number of the strain is CGMCC (China General Microbiological Culture Collection Center) No.34456. The invention also discloses a preparation method of the Streptomyces tauricus zhanshen-LZ-12. The strain has the functions of degrading cellulose, decomposing protein, fixing nitrogen, resisting salt, degrading phenolic acid autotoxic substances (benzoic acid, p-hydroxybenzoic acid and cinnamic acid) and the like. Bacterial powder obtained after fermentation of the bacterial strain is uniformly mixed with bacillus bacterial powder to obtain the multifunctional bacterial agent, and when straw returning or composting is carried out, the multifunctional bacterial agent is adopted, straw decomposition can be accelerated, soil ecology can be improved, crop growth can be promoted, and the stress resistance of crops can be enhanced.

The invention discloses a method for producing mRNA (messenger ribonucleic acid) template plasmids by fermenting escherichia coli. When the recombinant escherichia coli is fermented and cultured, a seed solution of the recombinant escherichia coli is inoculated into a basic culture medium to be fermented and cultured until the OD600 value of fermentation liquor is 18-22, then a fed-batch culture medium is continuously added at the feeding rate of 5-15 mL / L / h to be subjected to continuous fed-batch fermentation culture, the basic culture medium contains 0.05-0.2 mmoL / L of ferric salt compound and 0.05-0.2 mmoL / L of copper chloride dihydrate, and the basic culture medium contains 0.05-0.2 mmoL / L of ferric salt compound and 0.05-0.2 mmoL / L of copper chloride dihydrate. The basal culture medium contains 10-15 g / L of copper chloride dihydrate and 100-300 mg / L of p-hydroxybenzoic acid, the carbon source of the basal culture medium contains 0.1-0.3 mmoL / L of a ferric salt compound, 0.1-0.3 mmoL / L of copper chloride dihydrate and 100-300 mg / L of p-hydroxybenzoic acid, the carbon source of the fed-batch culture medium contains 360-480 g / L of glycerol, and the ferric salt compound is one or more of ferrous citrate, ferric ammonium citrate or ferrous sulfate heptahydrate. According to the method, the yield and superhelix content of the mRNA template plasmids are improved by optimizing the culture medium formula and culture conditions, and large-scale production of the high-quality target mRNA template plasmids is facilitated.

The invention relates to the technical field of liquid crystal polymers, and discloses a high-temperature-resistant, electricity-conducting and heat-conducting graphene-LCP material and a preparation method thereof.The preparation method comprises the steps that a diacid monomer, p-hydroxybenzoic acid and 4, 4 '-bis (4-hydroxyphthalimide)-benzamido benzene are subjected to a carboxyl reaction, liquid crystal polyarylester is obtained and mixed with graphene oxide, and the high-temperature-resistant, electricity-conducting and heat-conducting graphene-LCP material is obtained. The liquid crystal polyarylester molecular chain contains an imide ring, so that the thermal decomposition mass loss temperature of the liquid crystal polyarylester LCP material can be improved. The liquid crystal polyarylester contains amido bonds and forms strong interaction with hydroxyl and carboxyl on the surface of the graphene oxide, the interfacial compatibility between the graphene oxide and the liquid crystal polyarylester can be improved, the graphene oxide does not need surface modification and has good dispersity in the LCP material, a conductive path is formed, and the conductivity and the antistatic performance are improved.

Use of a lubricating composition in an ammonia combustion engine The present invention relates to the use of a lubricating composition comprising at least one alkali or alkaline-earth salt of hydroxybenzoic acid, optionally substituted by at least one hydrocarbon group, called hydroxybenzoate salt, in an ammonia combustion engine. It also relates to the use of said hydroxybenzoate salt as a corrosion retardant in an ammonia combustion engine. It also relates to a method for lubricating an ammonia combustion engine, comprising a step of bringing at least one mechanical part of said engine into contact with a lubricating composition comprising at least said hydroxybenzoate salt. Figure for abstract: None

The invention discloses a smoke-suppression flame-retardant ecological board and a preparation method thereof. The ecological board comprises a base material, a flame-retardant adhesive layer and a facing layer which are sequentially stacked, wherein the flame-retardant adhesive layer is prepared from the following raw materials: 100 parts of urea-formaldehyde resin, 10-15 parts of a phosphorus-nitrogen composite flame retardant and 5-10 parts of flame-retardant filler; the preparation method of the phosphorus-nitrogen composite flame retardant comprises the following steps: carrying out an aminomethylation reaction on p-hydroxybenzoic acid, ethanolamine and paraformaldehyde which are used as raw materials in a molar ratio of 1: (1-1.2): (2-2.2) to prepare a Mannich base intermediate; and carrying out substitution reaction on the Mannich base intermediate and phosphonitrilic chloride trimer serving as raw materials according to the molar ratio of (3-7): 1. The phosphorus-nitrogen flame retardant disclosed by the invention is high in content of phosphorus and nitrogen elements and uniform in distribution ratio, and has more excellent synergistic smoke suppression and flame retardant effects compared with an existing physical compound system.

The invention belongs to the technical field of scale inhibitors, and particularly relates to a slow-release scale inhibitor and a preparation method thereof.The preparation method comprises the steps that 3, 4, 5-allyl trihydroxybenzoate, itaconic acid, sodium hydrogen sulfite, methacryloyloxyethyl-n-hexadecyl-dimethyl ammonium bromide and deionized water are mixed, after water bath heating, an ammonium persulfate aqueous solution is slowly added, and the scale inhibitor is obtained after reaction; the preparation method comprises the following steps: dissolving agar in deionized water, adding polyethylene glycol modified sodium alginate and a scale inhibitor into the deionized water, stirring, dropwise adding into edible oil to obtain gel microspheres, adding the gel microspheres into a calcium chloride aqueous solution, slowly stirring, cross-linking, cleaning and drying to obtain the slow-release scale inhibitor. The hydrogel microspheres swell to slowly release the scale inhibitor, meanwhile, the released scale inhibitor is hydrolyzed in water, ester groups are slowly broken, polycarboxylic acid, 3, 4, 5-trihydroxybenzoic acid and hydroxyethyl-n-hexadecyl-dimethyl ammonium bromide are slowly released, and good scale inhibition and corrosion inhibition effects are achieved.

The present invention relates to the use of a lubricant composition comprising at least one alkali salt or alkaline earth salt of hydroxybenzoic acid, optionally substituted with at least one hydrocarbon group, referred to as hydroxybenzoate salt, in an ammonia combustion engine. The invention also relates to the use of said hydroxybenzoate salt as a corrosion retardant in an ammonia combustion engine. The invention further relates to a method for lubricating an ammonia combustion engine, comprising a step of bringing at least one mechanical part of said engine into contact with a lubricant composition comprising at least said hydroxybenzoate salt.

The invention discloses a polyurethane bonding layer resin material, which belongs to the field of high polymer material and structure bonding, and comprises 40-60 parts by mass of a prepolymer A which is obtained by reacting 4, 4 '-diphenylmethane diisocyanate with polyether polyol with the molecular weight of 1800-2200g / mol and the hydroxyl value of 55-65mgKOH / g in the absence of a metal catalyst, and the mass fraction of residual NCO is 3-7%; the hydroxyl-terminated chain extender B is a blend of 1, 4-butanediol and 1, 6-hexanediol, and the molar ratio of the 1, 4-butanediol to the 1, 6-hexanediol is (1.0: 1)-(2.0: 1); the aromatic block modifier C is formed by condensation polymerization of p-hydroxybenzoic acid and isophorone diisocyanate, and the content of aromatic rings in the aromatic block modifier C is 30%-50%; 3 to 8 parts of a fluorine-containing isocyanate modifier D; 1 to 5 parts of an anti-migration stable component E; and 2-6 parts of a crosslinking density regulator F. The adhesive provided by the invention has excellent damp-heat aging resistance, dimensional stability and solvent resistance, high bonding strength and stable interface bonding, and is suitable for long-term bonding application in a complex environment.

The invention discloses an application of 2, 3-dihydroxybenzoic acid in preparation of an antitumor drug. Researches find that 2, 3-dihydroxybenzoic acid can inhibit proliferation, migration and invasion of colorectal cancer cells in vitro and promote cell cycle arrest and cell apoptosis, and 2, 3-dihydroxybenzoic acid can inhibit growth of mouse transplanted tumors in vivo and promote cell apoptosis; the 2, 3-dihydroxybenzoic acid has a remarkable treatment effect on mouse colon cancer and can improve the immunotherapy effect; moreover, the 2, 3-dihydroxybenzoic acid small molecule substance, as an inhibitor of fatty acid synthase (FASN), plays an important role in inhibiting colorectum.

The invention discloses a PVDF / PFA composite filter material for sewage treatment and a preparation method of the PVDF / PFA composite filter material, and relates to the technical field of water treatment. When the filtering material is prepared, firstly, N-propenylimidazole and 1-chloro-3-phenylpropane react to prepare vinyl imidazolium salt, PVDF subjected to alkali treatment is grafted with the vinyl imidazolium salt, then the PVDF and 5-aza-uracil react, and modified PVDF is obtained; secondly, enabling resorcinol, 3, 5-dihydroxybenzoic acid and formaldehyde to react to obtain porous microspheres, and sulfonating the porous microspheres through chlorosulfonic acid to obtain modified microspheres; finally, PVDF, PFA, polyoxyethylene and the modified microspheres are mixed and subjected to melt spinning, and a fiber membrane is prepared; and carrying out in-situ generation of ferroferric oxide, and activating with hypochlorous acid to obtain the PVDF / PFA composite filter material for sewage treatment. The filter material prepared by the invention has good antibacterial, hydrophilic and photocatalytic degradation properties.

The invention discloses an anti-UV hydrolysis-resistant PET functional master batch and a preparation method thereof, UV absorbing groups such as isophorone diester and 2, 4-dihydroxybenzoic acid are introduced to enhance the UV resistance, and neopentyl glycol and trimethylolpropane are introduced to enhance the hydrolysis resistance of a molecular chain. Besides, the Beta molecular sieve, the zinc metaborate and other auxiliaries are utilized, so that the uniform distribution of the light stabilizer and the ultraviolet light absorber in the molecular structure is improved, and the problem that the UV absorption performance and the hydrolysis resistance of the film are not uniform due to molecular arrangement change in the stretching process is effectively avoided. The ultraviolet resistance, the strength and the hydrolysis resistance of the film are improved through the synergistic effect of all the components in the formula, so that the application requirements of PET products in the fields of packaging, electronics, photovoltaics, automobiles, medical instruments and the like are met.

This invention belongs to the technical field of medicinal chemistry, specifically relating to a novel crystal form of cariprazine, specifically the cariprazine-4-hydroxybenzoic acid-methanol-hemihydrate crystal form and its preparation method. The novel cariprazine-fumaric acid crystal form provided by this invention comprises a basic unit of one molecule of cariprazine, one molecule of 4-hydroxybenzoic acid, one molecule of methanol, and 0.5 molecules of water. Its preparation method is simple to operate, the crystallization process is easy to control, and it has good reproducibility. The formation of a eutectic significantly enhances the solubility of cariprazine, exhibiting strong pharmaceutical value.

The invention relates to a continuous production method of ultra-pure 2, 3, 4, 4 '-tetrahydroxybenzophenone, which comprises the following steps: completely dissolving p-hydroxybenzoic acid in high-boiling range petroleum ether, and completely dissolving pyrogallic acid in the high-boiling range petroleum ether; the preparation method comprises the following steps: adding a p-hydroxybenzoic acid solution and a pyrogallic acid solution into an ultra-pure continuous reactor group, adding boron trifluoride diethyl etherate into the ultra-pure continuous reactor group at a flowing speed, reacting at 110-140 DEG C, adding the obtained reaction solution into the next ultra-pure continuous reactor group, stirring in ice water, filtering, washing and recrystallizing to obtain the 2, 3, 4, 5-tetramethyl-3, 5-dihydroxybenzoic acid. According to the present invention, the reaction time is substantially shortened, the conversion rate is 70-80%, the purity of the obtained electronic product is more than or equal to 99.2%, the content of the metal ions such as sodium, aluminum, copper, iron, calcium, zinc and boron is less than or equal to 60 ppb, the reaction materials, the reaction temperature and the reaction rate are controllable, the reaction is sufficient, the yield of the obtained target product is stable, and the method can be used for continuous production.

The present application provides a reversible thermochromic microcapsule pigment which is easily changed to a colored state from a colorless state by heating at a temperature in a living environment temperature range or a temperature close to a daily life temperature, and is sensitively recovered to the colorless state again. The reversible thermochromic microcapsule pigment of the present application is formed by enclosing a reversible thermochromic composition in a microcapsule, the reversible thermochromic composition comprising (A) an electron-donating colored organic compound, (B) a 4-hydroxybenzoic acid ester compound represented by the following general formula (1) as an electron-accepting compound (in the formula, R represents a linear or branched alkyl group having 12 to 22 carbon atoms), (C) a chain hydrocarbon compound or the like as a reaction medium in which reversible electron transfer reactions based on the above (A) and (B) occur, (D) a linear dibasic acid compound having 3 to 22 carbon atoms, and (E) an aromatic hydrocarbon compound or the like having a melting point of 50°C or higher.

The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and / or salt co-crystals are also provided.

The application relates to the technical field of functional films for semiconductor material processing, and discloses a low-residual, heat-resistant and anti-static semiconductor wafer cutting protection film. The protection film comprises a functional adhesive layer arranged on the surface of a base film, and the functional adhesive layer is composed of a synergistically modified polymer matrix, an organic small-molecule interface regulator, a heat-resistant toughening agent, an anti-static auxiliary agent, a residual inhibiting auxiliary agent and a rheological adjusting agent. The synergistically modified polymer matrix is formed by synergistic modification of an acrylate main chain polymer, 2-aminoethyl methacrylate, p-benzene dicarboxaldehyde, tannic acid and an amino-terminated polydimethylsiloxane, and the organic small-molecule interface regulator is 2,5-dihydroxybenzoic acid. The preparation method is simple and controllable, and is suitable for the semiconductor wafer cutting process with high requirements for cleanliness, heat resistance and static control.

The invention discloses a use method of 2, 4-dihydroxybenzoic acid dissolving and recrystallizing equipment, the 2, 4-dihydroxybenzoic acid dissolving and recrystallizing equipment comprises a closed dissolving kettle, a crystallization kettle and a mother liquor storage tank, the closed dissolving kettle, a first separator, a first filtrate storage tank and the crystallization kettle are connected in sequence, and the mother liquor storage tank is connected with a second separator. A discharge port of the crystallization kettle is connected with a feed port of a second separator, a filtrate discharge port of the second separator is connected with a liquid inlet of a second filtrate storage tank, and a liquid outlet of the second filtrate storage tank is communicated with a liquid inlet of the mother liquid storage tank through a third pipeline; the second pipeline between the first separation column and the second pump body is communicated with a liquid outlet of the mother liquid storage tank through a fourth pipeline; the second pipeline between the second pump body and the fourth pipeline is communicated with one end of a backflow pipeline, and the other end of the backflow pipeline is communicated with the first pipeline. The 2, 4-dihydroxy benzoic acid dissolving and recrystallizing equipment disclosed by the invention can be used for preparing 2, 4-dihydroxy benzoic acid with the purity of 99.68%, and the content of metal ions is reduced to 0.15 ppm.

The invention relates to the technical field of coatings, in particular to a graphene modified polyurethane coating with an electromagnetic shielding function. The coating is composed of deionized water, a graphene modified polyurethane emulsion, silver nanoparticles and an auxiliary agent, a synergistic modification system of hydroxylated graphene and p-hydroxybenzoic acid is introduced in a polyurethane prepolymerization stage, an organic-inorganic synergistic network with good interface compatibility is formed, the conductivity and electromagnetic shielding effect of the coating are remarkably improved through a formed compact conductive path, and meanwhile the flexibility and adhesive strength of polyurethane are kept. The coating is compact in structure, high in adhesive force, good in conductive continuity and excellent in electromagnetic shielding effect, and can be widely applied to the field of electromagnetic protection of electronic equipment shells, communication devices and aerospace equipment.

The invention relates to the technical field of biology, in particular to a pine bark polyphenol extract as well as a preparation method and application thereof. According to the present invention, the pine tree bark polyphenol extract is obtained through extraction with an ethanol solution, and the pine tree bark polyphenol extract mainly comprises 2-Hydroxy-4-hydroxybenzoic acid, Pinosylvin, Hispidulin, 3, 5-Dimethoxyphenol, 2, 3, 5, 4 '-Tetrahydroxystilbene, 2-O-beta-D-glucose, Quercetin-3-O-glucose, 6-O-Caffeoyl-D-glucose, Galvantinol, MeIAA and Rhapontigenin, and the pine tree bark polyphenol extract can be used for preparing the pine tree bark polyphenol extract, and can be used for preparing the pine tree bark polyphenol extract, the pine tree bark polyphenol extract, the pine tree bark polyphenol extract, the pine tree bark polyphenol extract, the pine tree bark polyphenol extract, the pine tree bark polyphenol extract and the preparation method thereof, the pine bark polyphenol extract can be used for effectively relieving LPS (lipopolysaccharide)-induced intestinal barrier injury of weaned piglets by regulating intestinal flora (improving Pediococcus abundance and reducing Alloprevotella abundance) and a tryptophan-AhR pathway under the condition that the addition amount of the pine bark polyphenol extract is lower than 0.05 wt%.

The invention relates to an aqueous pigment paste comprising or containing a) an organic and / or inorganic pigment, b) a humectant, c) a preservative such as alkali sorbates or the water-soluble salts of para-hydroxybenzoic acid, and d) water, wherein the aqueous pigment paste has a pH value in the range of 4.0 to 6.5 or is adjusted to a pH value in the range of 4.0 to 6.5. The invention further relates to a kit-of-parts coating system comprising or formed from a) at least one aqueous pigment paste according to the invention and b) at least one aqueous coating compound, as well as a tinted aqueous coating system obtainable from the kit-of-parts coating system by mixing the aqueous pigment paste A) with the aqueous coating compound B).Furthermore, the invention relates to a method for tinting an aqueous coating compound as well as the use of the aqueous pigment paste according to the invention for coloring water-based paints, varnishes, glazes, plasters, primers and / or fillers or for the production of or as interior paint, facade paint, filler, plaster, primer, varnish, glaze or pigment paste or as a component thereof.

The invention discloses a generalized pustular psoriasis diagnosis marker based on metabonomics and application of the generalized pustular psoriasis diagnosis marker. The diagnostic marker is prepared from one or more of the following 35 compounds: pyruvic acid, alpha-ketoisovaleric acid, 2-hydroxybutyric acid, 3-hydroxybutyric acid, methane thiophosphoric acid, proline, uracil, tranexamic acid, 4-aminobutyric acid, threonine, scopoletin, dodecanol, N-methyl-L-leucine, L-cysteine-glycine and L-kynurenine. The feed additive is prepared from the following raw materials: 3-hydroxybenzoic acid, allantoin, delta-tocopherol, xylofuranose, glucose-1-phosphoric acid, pyrophosphate, taurine, L-asparagine, phthalic acid, 4-(dimethylamino) azobenzene, 5-tert-butyl-1h-indole-2, 3-dione, quinic acid, glucose, histidine, lysine, palmitic acid, 7-methylguanine, oleic acid and whale acid. The marker can be used for accurately distinguishing patients with generalized pustular psoriasis from healthy people.

The invention discloses a high-temperature-resistant liquid crystal polymer substrate for ultrathin flexible display, which belongs to the technical field of flexible display and comprises a modified liquid crystal polymer and a functional additive dispersed in the modified liquid crystal polymer. The modified liquid crystal polymer is prepared by polymerizing a monomer composition, and is specifically prepared from 38 to 42 parts of p-hydroxybenzoic acid, 28 to 30 parts of 4, 4 '-biphenol, 5.6 to 6.0 parts of terephthalic acid, 4.4 to 5.0 parts of 2, 6-naphthalic acid, 2.7 to 3.3 parts of isophthalic acid, 9 to 11 parts of 2, 2-bis (3, 5-difluoro-4-hydroxyphenyl) hexafluoropropane, 4.5 to 5.5 parts of N, N'-dihydroxypyromellitic diamine, 9 to 11 parts of 9, 9-bis [4-(4-methoxycarbonyl phenoxy) phenyl] fluorene and 1, 2-bis (4-(4-methoxycarbonyl phenoxy) phenyl] fluorene. The component A is prepared from 5.5 to 6.5 parts of 1, 4-cyclohexanedimethanol; the functional additive comprises an azobenzene derivative, a hot acid generator and a hydrogen bond enhancer; through the synergistic effect of a specific monomer combination, a functional additive and an optimization process, the technical bottleneck that heat resistance, transparency, dimensional stability and flexibility of an existing material are difficult to consider at the same time is broken through.

The invention belongs to the technical field of solid waste treatment and utilization, and particularly relates to modified manganese slag and application thereof in preparation of a cement material. The modified manganese slag disclosed by the invention is prepared by a method comprising the following steps: uniformly mixing maleic anhydride grafted polyethylene, epoxy group modified manganese slag, epoxy group modified nano alumina fiber and epoxy group modified basalt fiber, and then performing melt extrusion to obtain a polyethylene grafted manganese slag-polybasic fiber compound, and uniformly mixing the polyethylene grafted manganese slag-polybasic fiber compound and 5-chlorosulfonyl-2-hydroxybenzoic acid, and carrying out melt extrusion to obtain the modified manganese slag. The basalt fiber and the nano alumina fiber are combined with the manganese slag through chemical bonds and polyethylene long chains to form a compound, so that the combination stability and dispersion uniformity of the basalt fiber, the alumina fiber and the manganese slag can be improved, and the basalt fiber and the alumina fiber can play an anchoring role in a cement material; the mechanical strength and the low-temperature freezing resistance of the cement material are improved.

The present application belongs to the technical field of daily chemical preparation, and particularly relates to a gynecological gel for inhibiting bacteria, regulating microecological balance and tightening vagina and a preparation method thereof. The gynecological gel comprises the following raw materials in mass fractions: 0.5-1 parts of carbomer, 0.04-0.09 parts of sodium hydroxide, 1-3 parts of collagen, 0.01-0.06 parts of sodium hyaluronate, 0.5-1.5 parts of isomaltooligosaccharide, 2-5 parts of propylene glycol, 0.05-0.3 parts of hydroxybenzoic acid methyl ester, 0.02-0.15 parts of hydroxyphenyl ethyl ester, 0.1-1.5 parts of hydrogenated lecithin, 1-6 parts of 1,3-butanediol, 3-5 parts of glycerol, 0.5-1 part of xanthan gum and 70-90 parts of water. The present application uses buckwheat filtrate to prepare collagen, and the active ingredients in the buckwheat filtrate can penetrate the cell membrane of pathogenic bacteria to play an antibacterial role; the collagen can repair the vaginal mucosa barrier and reduce the adhesion and invasion of pathogenic bacteria; therefore, after being compounded with the raw materials such as carbomer, sodium hydroxide, sodium hyaluronate, isomaltooligosaccharide and propylene glycol, the multiple components can synergistically promote the synthesis and repair of collagen fibers and improve the elasticity of tissues.

The invention discloses a positive pole piece and a preparation method thereof, a diaphragm-free battery and a battery. The positive pole piece comprises a positive pole current collector and a positive pole active material layer arranged on at least one side of the positive pole current collector, the positive pole active material layer comprises a polymer, and the polymer is formed by polymerizing at least one of small molecules of the following raw material components: vinylethylene carbonate, vinylene carbonate, 2, 3, 4-trimethyl-1, 3-pentanedione, 2, 3, 4-trimethyl-1, 3-pentanedione and 2, 3, 4-trimethyl-1, 3-pentanedione. The adhesive is prepared from 2, 4-hexadienoic acid, allyl trifluoroacetate, diethyl allylmalonate, allyl methacrylate, allyl chloroformate, allyl phenylacetate, allyl acetate, allyl 4-hydroxybenzoate and allyl phenoxyacetate. The adhesive is prepared from the following raw materials: 1, 4-hexadienoic acid, allyl trifluoroacetate, diethyl allylmalonate, allyl methacrylate, allyl chloroformate, allyl phenylacetate, allyl acetate, allyl 4-hydroxybenzoate and allyl phenoxyacetate. The positive pole piece provided by the invention comprises the polymer, so that the interface impedance can be reduced, and the rate capability of the battery can be improved.

The invention relates to the technical field of catalysts, in particular to a preparation method of an iron-cobalt oxide and Beta molecular sieve composite catalyst and application of the iron-cobalt oxide and Beta molecular sieve composite catalyst to demethoxylation of lignin derivative vanillic acid. Meanwhile, due to the interaction of iron and cobalt species, the acid site of the catalyst is enhanced, and adsorption and activation of a substrate are facilitated; the iron-cobalt oxide is combined with the Beta molecular sieve, and the reaction activity of demethoxylation is improved through cooperation of metal / zeolite; the Co0 / Fe0. 04Co0. 96O-Beta composite catalyst is used for a vanillic acid demethoxylation catalytic reaction, the reaction is performed for 2 hours under the condition of 0.4 MPa H2 and 0.4 MPa CO2, the substrate conversion rate reaches 96.07%, the p-hydroxybenzoic acid selectivity reaches 86.96%, and the target product yield is 83.54%.

The invention provides certain nicotine salts, co-crystals, and salt co-crystals and provides novel polymorphic forms of certain nicotine salts. In particular, nicotine salts with mucic acid, 3,5-dihydroxybenzoic acid, and 2,3-dihydroxybenzoic acid, and crystalline polymorphic forms of nicotine 4-acetamidobenzoate, nicotine gentisate, and nicotine 1-hydroxy-2-naphthoate are described. The invention further provides methods of preparation and characterization of such nicotine salts, co-crystals, and salt co-crystals and polymorphic forms thereof. In addition, tobacco products, including smoking articles, smokeless tobacco products, and electronic smoking articles comprising nicotine salts, co-crystals, and / or salt co-crystals are also provided.

The present invention provides a vasospasm inhibitor and an oral composition for inhibiting vasospasm that can suppress abnormal vasoconstriction (vasospasm). [Solution] A vasospasm inhibitor and an oral composition for inhibiting vasospasm, containing as an active ingredient at least one compound selected from the group consisting of 2,5-dihydroxybenzoic acid, trans-3-caffeoylquinic acid, trans-4-caffeoylquinic acid, trans-5-caffeoylquinic acid, and 2-hydroxybenzoic acid, or a salt thereof.

The invention relates to the technical field of medical crystallization, and particularly discloses benzocain-2, 6-dihydroxy benzoate monohydrate as well as a preparation method and application thereof. The benzocain-2, 6-dihydroxy benzoate monohydrate has the following characteristic diffraction peaks in an X-ray powder diffraction pattern which is determined by adopting rays: the diffraction angle values are 6.28 degrees, 12.48 degrees, 15.12 degrees, 17.40 degrees, 19.44 degrees, 22.92 degrees, 23.88 degrees, 26.46 degrees and 27.76 degrees. According to the invention, benzocaine is taken as an active ingredient, 2, 6-dihydroxybenzoic acid monohydrate is taken as a salt-forming agent, and the formed salt can obviously improve the water solubility, antibacterial property and stability of benzocaine; and the preparation method is simple to operate, low in energy consumption, low in solvent consumption, even free of solvent, good in product reproducibility and beneficial to industrial production.

The invention belongs to the field of catalysts, and particularly relates to a nitrogen-sulfur co-doped Fe-based diatomic catalyst as well as a preparation method and application thereof. The preparation method comprises the following steps: by taking hexamethylenetetramine and 2, 4-dihydroxybenzoic acid as hard templates and sodium oleate, P123 and polyethylene glycol with the molecular weight of 4000 as soft templates, uniformly mixing, carrying out hydrothermal reaction to prepare HBP, loading Fe ions, and carrying out nitrogen and sulfur doping with thiourea through high-temperature calcination to obtain the nitrogen and sulfur doped hollow carbon bowl loaded Fe-based diatomic catalyst. The catalyst shows excellent ORR catalytic activity under an alkaline condition and shows excellent application performance in a zinc-air battery.