33 results about "Toluidine" patented technology

The invention discloses high-wear-resistance tread rubber for a mine tire and a preparation method of the high-wear-resistance tread rubber, and relates to the technical field of tires. According to the invention, the ATT-Si / AL additive is creatively introduced and used together with carbon black as a wear-resistant main body, and an alkaline accelerator formaldehyde p-toluidine condensation compound and a conventional accelerator are synergistically applied to a wear-resistant tread rubber system for the first time; wherein the accelerator formaldehyde-p-toluidine condensation compound not only provides flat vulcanization characteristic and excellent aging resistance for the rubber material, but also solves the problems of'filler-rubber 'interface weakening and stress concentration caused by high-hardness filler by activating silanization reaction and catalyzing covalent bonding between a sulfur cross-linked network and a rigid filler interface through the alkalinity of the accelerator formaldehyde-p-toluidine condensation compound; the ATT-Si / AL additive and the accelerator formaldehyde p-toluidine condensation compound cooperate to form a physical-chemical dual enhanced network, so that the tread rubber keeps high strength and high wear resistance level under extreme wear.

The application provides a process and equipment for removing m-methylaniline and indole in coking nanofiltration concentrated water, a catalyst and a preparation method thereof, and the water quality of the coking nanofiltration concentrated water is as follows: conductivity 21300-34560 muS / cm, sulfate ion 567-1340 mg / L, m-methylaniline 45-78 mu g / L, and indole 23-39 mu g / L; the process comprises the following treatment steps: the coking nanofiltration concentrated water enters the ozone catalytic tower from the bottom of the tower and flows out from bottom to top, and the ozone catalytic tower is internally provided with a modified peanut shell biochar catalyst; after the ozone catalytic reaction, the water quality of the coking nanofiltration concentrated water is as follows: conductivity 21300-34560 muS / cm, sulfate ion 567-1340 mg / L, m-methylaniline 3-7 mu g / L, and indole 1-6 mu g / L.

The present invention relates to a synergistic antiknock fuel additive comprising a mixture of N-methyl-p-anisidine and m-toluidine in a volume ratio from 45:55 to 95:5; to the use of said fuel additive to increase the octane rating of a gasoline; and to a gasoline fuel composition comprising said fuel additive.

This invention discloses a self-microporous polymer, a self-microporous ion exchange membrane, its preparation method, and its applications, belonging to the field of polymer materials technology. The polymer uses 1,3,5-tris(4-aminophenyl)benzene (TAPB), o-toluidine (DMBP), and dimethylformaldehyde as monomers. Utilizing the rigid, distorted, and non-densely stacked molecular structures of TAPB and DMBP, a polymer material with an inherent sub-nanometer microporous structure and its corresponding homogeneous ion exchange membrane are prepared. The formed self-microporous structure constructs continuous ion transport channels within the membrane, where the sub-nanometer-scale micropores impart a significant size sieving effect, thereby achieving selective separation of monovalent / polyvalent anions. Furthermore, by quaternizing the membrane material, fixed positively charged groups are introduced onto the polymer backbone. These positively charged groups generate significant electrostatic repulsion, enabling selective separation of monovalent / polyvalent cations, particularly suitable for the efficient separation of lithium and magnesium ions.

The invention belongs to the technical field of fungaltoxin detection, and particularly relates to a Raman beacon COF nanoflower and a preparation method and application thereof. The method comprises the following steps: dissolving trialdehyde phloroglucinol, o-bitoluidine and polyvinylpyrrolidone in methanol, carrying out ultrasonic uniform mixing, adding a catalyst to carry out a reaction, adding benzaldehyde after the reaction is finished, continuously carrying out a standing reaction, centrifuging, washing and redissolving to obtain TpDBD-COF nanoflowers, dissolving the TpDBD-COF nanoflowers in a mixed solution of ethanol and water, adding AgNO3, carrying out ultrasonic adsorption, and carrying out vacuum drying to obtain the TpDBD-COF nanoflowers. After adsorption is finished, trisodium citrate is added for a heating reaction, centrifugation, washing and redissolution are performed, and the Raman beacon COF nanoflower is obtained. The COF nanoflower prepared by the invention has a highly enhanced stable Raman signal, the surface group has the advantage of being directly used for biomolecule coupling, and the COF nanoflower can be specifically used for sensitively detecting T-2 toxin in a sample.

This application belongs to the technical field of mycotoxin detection technology, specifically relating to a Raman beacon COF nanoflower, its preparation method, and its application. The method involves dissolving trialdehyde phloroglucinol, o-toluidine, and polyvinylpyrrolidone in methanol, ultrasonically mixing, adding a catalyst for reaction, adding benzaldehyde after the reaction, allowing the mixture to stand, centrifuging, washing, and redissolving to obtain TpDBD-COF nanoflowers. These nanoflowers are then dissolved in a mixed solution of ethanol and water, followed by the addition of AgNO3 and ultrasonic adsorption. After adsorption, trisodium citrate is added for heating reaction, centrifuging, washing, and redissolving to obtain the Raman beacon COF nanoflowers. The COF nanoflowers prepared by this invention exhibit a highly enhanced and stable Raman signal, and their surface groups have the advantage of being directly used for biomolecule coupling, specifically for the sensitive detection of T-2 toxin in samples.

The present application provides a long-life low-friction grease composition and a preparation method thereof. The grease composition comprises the following raw materials by weight: 20-35 parts of high-alkaline calcium sulfonate, 50-65 parts of base oil, 2-6 parts of diisocyanate, 1-5 parts of p-toluidine, 0.5-2 parts of urea, 1-4 parts of conversion agent, 1-2 parts of calcium carbonate, 1-2 parts of calcium hydroxide, 1-4 parts of small-molecule acid, 3-5 parts of fatty acid, 0.5-2 parts of solid friction-reducing agent, 0.5-3 parts of antioxidant, 0.5-2 parts of surfactant, and 0.5-2 parts of passivator. The grease composition has excellent friction-reducing capacity and extreme pressure performance, and has a long service life.

The application discloses a cold storage and heat preservation plastic foam and a preparation method thereof. The combined material formula comprises a boric acid polyether polyol and a high-hydroxyl-value o-toluidine polyether polyol. The boric acid polyether polyol has a characteristic of a triangular stable structure of boron atoms, and can improve the strength and dimensional stability of a plastic product and delay the attenuation of the strength and dimensional stability of the plastic product in application. The boric acid polyether polyol contains a part of insoluble B=O structure, which is easy to precipitate in the early stage of the reaction of the combined material with isocyanate, forms stable nucleation points, and through the synergistic effect of the high-hydroxyl-value o-toluidine polyether polyol, the cross-linking of product foam fibers is enhanced, the bubbles are inhibited and the bubbles are made more delicate, and the thermal conductivity of the product is reduced. The rapid cross-linking can reduce the volatilization of a foaming agent and reduce the surface bubbles at the end of product flow.

The invention belongs to the field of vinyl elastomers, and particularly relates to a flame-retardant high-strength polyethylene blow molding material and a preparation method thereof.The flame-retardant high-strength polyethylene blow molding material is prepared from 100 parts of high-density polyethylene, 20-30 parts of organic montmorillonite modified flame retardant, 3-5 parts of maleic anhydride grafted polyethylene, 0.3-0.5 part of composite antioxidant and 0.5-1.5 parts of polyethylene wax; the preparation method comprises the following steps: dispersing long-chain organized montmorillonite in toluene, adding gamma-aminopropyltriethoxysilane and triethylamine, and carrying out a reflux reaction at 80 DEG C under the protection of nitrogen for 6 hours to obtain long-chain organized montmorillonite containing active amino groups; the preparation method comprises the following steps: re-dispersing long-chain organic montmorillonite containing active amino groups in toluene, adding pentaerythritol spiro-phosphoryl p-toluidine, and carrying out a reflux reaction; the organic montmorillonite modified flame retardant is obtained; the flame-retardant high-strength polyethylene blow molding material prepared from the organic montmorillonite modified flame retardant has efficient flame retardance and excellent mechanical properties.

The present invention provides a polyimide film, comprising: a copolymer obtained by copolymerizing a dianhydride monomer comprising pyromellitic dianhydride (PMDA) and a diamine monomer comprising 4, 4 '-diaminodiphenyl ether (ODA) and m-bitoluidine (m-TD), wherein the film has a coefficient of thermal expansion (CTETD) in a transverse direction (TD) measured at a temperature range of 50 DEG C to 200 DEG C and a temperature rise rate of 10 DEG C / min of-5 ppm / DEG C to 2.5 ppm / DEG C, and a modulus of 8 GPa or more.

The application discloses a low-modulus bone cement and a preparation method thereof, and the solid-liquid ratio of powder and liquid is 2g-3g:1mL; the powder comprises the following raw materials in percentage by mass: 52%-89.5% of acrylic resin, 10%-40% of barium sulfate and 0.5%-8% of powdered phospholipid; and the liquid comprises the following raw materials: 0.5%-5% of N, N-dimethyl-p-toluidine, 0.05%-2% of hydroquinone and 93%-99.45% of methyl methacrylate. The powdered phospholipid is introduced into the bone cement powder to modify the bone cement, reduce the excessively high elastic modulus of the bone cement and prevent secondary injuries such as the fracture of adjacent vertebral bodies caused by the high elastic modulus of the bone cement after filling. Meanwhile, the powdered phospholipid is uniformly distributed in the bone cement, meets the requirement of the bone cement compression strength≥70MPa in the bone cement forced standard and guarantees the demand of human mechanical strength support.

The application provides a preparation method of direct-spun brown, and belongs to the technical field of dye synthesis, and comprises the following steps: 1) mixing and reacting 4,4'-diamino benzoyl toluidine with a sodium nitrite solution under low-temperature conditions to generate a diazonium salt solution; 2) controlling the speed of dropping the diazonium salt solution into a coupling component, stirring and reacting to obtain a primary coupling product solution; 3) in the presence of a biodegradable cosolvent, the primary coupling product solution is added into gamma acid in batches for mixing and reacting, and the material concentration in the reaction system is controlled, and when the solid content of the reaction solution is greater than or equal to 45 %, the reaction is considered to be completed, and a secondary coupling product solution is obtained; and 4) directly performing spray drying on the secondary coupling product solution to obtain a direct-spun brown product. The method improves the standard degree and saturation of the color light of the product, the color light deviation ΔE is less than or equal to 1.0, the saturation reaches more than 95 % of a standard sample, the solid content of the secondary coupling reaction is improved, the purification process is eliminated, and the production cost is reduced.

Provided is a polyimide film including: a block copolymer including a dianhydride monomer including pyromellitic dianhydride (PMDA), and a diamine monomer including 4, 4 '-diaminodiphenyl ether (ODA) and m-bitoluidine (m-TD), in which a water absorption rate measured after storage in water at room temperature (20 DEG C to 25 DEG C) for at least one day is 2.5% or less, and a water absorption rate measured after storage in water at room temperature (20 DEG C to 25 DEG C) for at least one day is 2.5% or less; and the moisture absorption rate measured after being stored for at least one day in a constant temperature and humidity chamber (at a temperature of 25 DEG C and a humidity of 50%) is 1.5% or less.

The invention belongs to the field of biomedical materials, and relates to antibacterial bone cement, the bone cement comprises a powder and a liquid, the powder comprises polyacrylate and an antibacterial developer, and the liquid comprises N, N-dimethyl-p-toluidine, hydroquinone and methyl methacrylate; the antibacterial developing agent is a barium sulfate / copper oxide compound, the invention further provides a preparation method of the antibacterial developing agent in the antibacterial bone cement, an antibacterial bone cement set and a preparation method of the antibacterial bone cement set, the bone cement is endowed with certain antibacterial property by changing the composition of the developing agent, the elasticity modulus of the bone cement is reduced, and the bone cement set is prepared. And secondary injury caused by too high modulus of the bone cement is prevented.

The application discloses a preparation method of methyl-modified polyaniline and construction of a super capacitor with excellent cycle stability. The application introduces methyl functional groups on benzene rings by using N-phenyl-p-phenylenediamine (AD) and m-toluidine (mT) to copolymerize, weakens the intermolecular force of the polymer to control the polyaniline morphology, obtains aniline derivative copolymer Poly(AD-co-mT) (PACM) with high specific capacity, controls the intermolecular force by adopting aniline dimer and m-toluidine polymerization, thereby effectively controls the performance of polyaniline, and increases the capacity of the device. Meanwhile, the structure rupture of polyaniline in the electrochemical cycle process is repaired by using a large number of intermolecular hydrogen bonds provided by the amide bond in the hydrogen bond binder (SIR), thereby ensuring the cycle stability of the polyaniline electrode structure, and after 30000 cycles, the device has excellent capacity retention rate, and the super capacitor device with excellent stability is obtained.

The invention discloses an S-type heterojunction covalent organic framework composite catalyst and a preparation method thereof.The preparation method comprises the following steps that aromatic aldehyde, p-aniline, carbon quantum dots and a solvent are mixed and subjected to ultrasonic dispersion, and a mixed solution is obtained; mixing the mixed solution with a catalyst, and carrying out freezing-vacuumizing-nitrogen charging circulation to obtain a precursor solution; and carrying out solvothermal reaction on the precursor solution to obtain the S-type heterojunction covalent organic framework composite catalyst. According to the preparation method, aromatic aldehyde and p-aniline are taken as monomer materials and are mixed with the carbon quantum dots and the catalyst for solvothermal reaction, so that the S-type heterojunction covalent organic framework composite catalyst which is large in specific surface area, multiple in active sites, high in visible light utilization rate, high in photocatalytic activity and good in stability can be prepared; the method is widely used for removing organic pollutants in water bodies, can effectively remove the organic pollutants in different water bodies, and is high in use value and good in application prospect.

The invention discloses a preparation method of phentolamine EP impurity acid salt, which comprises the following steps: (1) taking a compound I resorcinol and a compound II p-toluidine as raw materials, and performing dehydration reaction to obtain an intermediate product III; (2) carrying out nucleophilic substitution reaction on the intermediate product III and benzyl bromide to generate an intermediate product IV; (3) carrying out nucleophilic substitution reaction on the intermediate product IV and ethyl bromoacetate to obtain an intermediate product V; (4) carrying out ester amidation reaction on the intermediate product V and N-tert-butyloxycarbonyl-1, 2-ethylenediamine to obtain an intermediate product VI; and (5) taking the intermediate product VI, and carrying out deprotection reaction to obtain a final product VII, wherein X represents hydrochloric acid, sulfuric acid, acetic acid, formic acid or trifluoroacetic acid. The purity of the prepared phentolamine EP impurity acid salt reaches 99% or above, the reaction yield is high, a test sample is provided for phentolamine research, and the phentolamine EP impurity acid salt has important research value in clinical pharmacokinetic research.

The invention discloses a technological synthesis method of 6-(N-ethyl-4-toluidine)-2-methylfluorane, and relates to the technical field of organic synthesis. The method comprises the following four steps of: (1) reacting resorcinol as shown in a formula I and p-toluidine as shown in a formula II in an acid catalysis system and an organic solvent at 110-145 DEG C for 20-28 hours to obtain a formula III; (2) carrying out reductive amination on the compound shown in the formula III and a compound shown in the formula IV (paraldehyde) in the presence of a catalyst under the hydrogen pressure of 0.1-5 MPa to obtain a compound shown in the formula V; (3) reacting the formula V with a formula VI (phthalic anhydride) in an organic solvent at 100-120 DEG C for 10-15 hours to obtain a formula VIII; and (4) carrying out dehydration condensation on the formula VIII and the formula IX (p-cresol) under an acidic condition to obtain a target product. Raw materials are easy to obtain, the yield of each step is larger than or equal to 80%, energy consumption and cost are reduced, operation safety is improved, the method is suitable for industrial production, and import dependence of high-end heat-sensitive materials can be broken through.

Unleaded aviation gasoline. An aviation gasoline fuel blend includes an unleaded aviation gasoline base fuel, with an effective amount of selected alkyl benzenes to improve the functional engine performance to avoid harmful detonation sufficient to meet or exceed selected standards for detonation performance requirements in full scale aircraft piston spark ignition engines designed for use with Grade 100LL avgas. Suitable alkylated benzenes may include a mixture of xylene isomers. Aromatic amines, such as m-toluidine, may also be added to increase MON. Base fuels may be a high quality aviation alkylate, or may be a commercial iso-octane, or a mixture of high quality aviation alkylate enhanced by iso-octane, or by commercial iso-octane mixtures, and may include iso-pentane or butane or both iso-pentane and butane in sufficient quantity to provide appropriate vapor pressure for the final fuel blend.

The present invention relates to the use of p-aminobenzoic acid in a method for preparing a compound selected from p-toluidine, p-chlorobenzonitrile, benzoic acid, aniline, and hydroxybenzomorpholine. In particular, the p-aminobenzoic acid is produced or obtained from a microorganism.

The present application relates to a kind of stainless steel powder self-developing bone cement and preparation method, bone cement is composed of two parts of powder and liquid, the ratio of powder and liquid is (2-3):1 g / mL;The component and mass percentage of powder are as follows:50-95% of methyl methacrylate polymer, 5-50% of 430 type ferrite-mannitol compound;Methyl methacrylate polymer contains benzoyl peroxide, and the mass percentage of benzoyl peroxide is 1-5%;The component and mass percentage of liquid are as follows:94.90-99.89% of methyl methacrylate monomer, 0.1-5% of N, N dimethyl-p-toluidine, 0.01-0.1% of hydroquinone.The present application can effectively improve the uniformity of bone cement developing and magnetic heat effect, magnetic heat temperature rate is fast, long-term stable development can be realized, and its mechanical strength and bone strength are approximately matched.

This invention discloses a method for preparing an acid pickling corrosion inhibitor, specifically comprising the following steps: Boiler water is distilled under reduced pressure and dried to obtain organic compound A; organic compound A is extracted with anhydrous ethanol, filtered, and washed to obtain organic compound B; toluidine, 80% sulfuric acid, potassium iodide, and organic compound B are added to a reactor and heated under reflux at 135–155°C for 12–18 hours to remove acid-insoluble substances. The filtrate is then neutralized with sodium hydroxide solution, concentrated under reduced pressure, and back-extracted with anhydrous ethanol. After drying, the acid pickling corrosion inhibitor is obtained. This invention effectively realizes the resource utilization of brewing boiler water, and the prepared acid pickling corrosion inhibitor exhibits excellent corrosion inhibition performance.

A first aspect of the invention relates to a purification process for obtaining vicinal toluenediamine. In a second aspect, the invention is directed to vicinal TDA (vTDA) obtained or obtainable from a process of the first aspect of the invention, comprising less than 100 weight-ppm of a toluidine compound of formula (I). A third aspect of the invention is related to vicinal TDA (vTDA) having a purity in the range of at least 99 weight- % and comprising less than 100 weight-ppm of a toluidine compound of formula (I).

The invention relates to a preparation method and application of a polyhydroxy phosphine-nitrogen flame retardant, the polyhydroxy phosphine-nitrogen flame retardant is prepared by recycling nitrogen-containing polyol in a thermosetting ester epoxy / amine cured product degradation product and further reacting, and the preparation method comprises the following steps: (1) carrying out alcoholysis on a thermosetting ester epoxy / amine cured product by using ethylene glycol and sodium hydroxide to obtain degradation liquid; (2) filtering the degradation liquid, carrying out rotary evaporation to remove ethylene glycol, aging with ethanol to remove salt, adjusting the pH value to be neutral, and carrying out rotary evaporation to obtain nitrogen-containing polyol EP / N-8OH; and (3) mixing the EP / N-8OH with triethylamine and tetrahydrofuran, dropwise adding diphenyl phosphinyl chloride under the protection of nitrogen, and performing treatment after reaction to obtain P, P-diphenyl phosphinic acid-3-[(5-{[bis (2, 3-dihydroxypropyl) amino] methyl}-3, 3, 5-trimethyl cyclohexyl) (2, 3-dihydroxypropyl) amino]-2-hydroxypropyl ester (polyhydroxy phosphine nitrogen flame retardant, DPP-P). The application method comprises the following steps: mixing DPP-P with bisphenol A epoxy resin E-51, a curing agent 1, 2, 3, 6-tetrahydrophthalic anhydride and a catalyst N, N-dimethylamine, and carrying out preheating, defoaming and stepped heating curing, so that the prepared flame-retardant modified epoxy resin E51-DPP-P has good flame retardance and mechanical properties.

The invention provides a method for simultaneously detecting p-toluidine, p-fluoroaniline and o-fluoroaniline in a medicine, which comprises the following steps: respectively detecting a reference solution and a test solution by adopting an ultra-high performance liquid chromatography-mass spectrometry technology, and calculating according to an external standard method to determine the content of p-toluidine, p-fluoroaniline and o-fluoroaniline in a sample. The method has the advantages of simplicity in operation, good linear relation, low detection limit, high recovery rate and the like.

The invention discloses a method for preparing high-purity 3-chloro-p-toluidine by a two-stage melt crystallization method, and relates to the technical field of preparation of 3-chloro-p-toluidine, and the method comprises the following steps: carrying out preliminary filtration on crude product 2B oil containing 3-chloro-p-toluidine to remove solid impurities, heating the filtered substance to 110 + / -3 DEG C, and removing moisture to obtain a uniform melt; transferring the uniform melt into a composite crystallizer for primary crystallization; after the primary crystallization is completed, raising the temperature at the rate of 0.2-1 DEG C / min and carrying out sweating operation; melting the sweated crystal again, and repeating the crystallization and sweating processes for secondary crystallization to obtain a pure 3-chloro-p-toluidine product; according to the method, the high-purity 3-chloro-p-toluidine product is obtained through primary filtration treatment, primary crystallization, sweating operation and secondary crystallization through the composite crystallizer, the highest operation temperature is only about 110 DEG C, corrosion of chloride ions to equipment is greatly reduced in a low-temperature environment, and the quality stability of the product is improved.

Disclosed are a composite resin denture porcelain block, a preparation method thereof and a composite resin denture. The composite resin denture porcelain block includes 0.1% to 15% of carbamate dimethacrylate, 0.1% to 10% of bisphenol A-di glycidyl methacrylate, 3% to 20% of triethylene glycol dimethacrylate, 35% to 85% of glass powder, 0.1% to 8% of ZrO2, 3% to 15% of SiO2, 0.1% to 40% of ZrO2—SiO2 composite powder, 2% to 17% of diatomite, 0.01% to 3% of benzoyl peroxide, 0.01% to 3% of N,N dihydroxyethyl p-toluidine, 0.01% to 3% of 2,6 di-tert-butyl p-cresol, 0.001% to 0.2% of iron oxide red, 0.001% to 0.2% of iron oxide black, and 0.001% to 0.5% of iron oxide yellow. The composite resin denture porcelain block of the present application uses carbamate dimethacrylate, bisphenol A-di glycidyl methacrylate, and triethylene glycol dimethacrylate as the resin matrix.

The present application relates to a kind of magnetic antibacterial bone cement and preparation method, bone cement is composed of two parts of powder and liquid, the ratio of powder and liquid is (2-3):1g / mL, powder component and mass percentage are as follows: polymethyl methacrylate 45-89%, 440C martensitic steel silver powder 10-50%, benzoyl peroxide 1-5%;In 440C martensitic steel silver powder, the mass percentage of 440C martensitic stainless steel powder is 65-95%, and the mass percentage of silver powder is 5-35%;Liquid component and mass percentage are as follows: methyl methacrylate monomer 94.90-99.89%, N, N dimethyl-p-toluidine 0.1-5%, hydroquinone 0.01-0.1%.The bone cement of the present application has moderate magnetic heating rate, can realize long-term stable development, and has certain bacteriostasis.

The invention provides disperse blue 360 and a preparation method thereof. The preparation method comprises the following steps: a diazotization step: under an acidic condition, carrying out a diazotization reaction on 2-aminothiazole and a diazotization reagent to obtain a diazonium solution; a coupling step: carrying out a coupling reaction on N, N-diethyl m-toluidine and the diazonium liquid to obtain a coupling product; nitration: carrying out nitration reaction on the coupling product and nitric acid to obtain a nitration product containing disperse blue 360. The preparation method disclosed by the invention is simple and easy to implement, the stability of the coupled material is remarkably improved, and the decomposition loss of the raw material in the nitration process of the 2-aminothiazole is effectively reduced. The preparation method disclosed by the invention can greatly improve the yield of the product and remarkably save the production cost, and is suitable for large-batch production.

The invention discloses high-adhesion thermoplastic polyimide slurry and a preparation method and application thereof, and belongs to the technical field of high polymer materials, and the preparation method comprises the following steps: under the protection of inert gas, adding o-bitoluidine and bisphenol A type diether dianhydride into a polar aprotic solvent to prepare a polyamide acid solution; adding a dehydrating agent and a catalyst into the polyamide acid solution, and carrying out chemical imidization reaction to prepare thermoplastic polyimide reaction slurry; dropwise adding the reaction slurry into absolute ethyl alcohol for settling, washing, drying and crushing to obtain thermoplastic polyimide powder; the thermoplastic polyimide powder is re-dissolved in the polar aprotic solvent, and the thermoplastic polyimide slurry is prepared through ultrasonic dispersion and filtration. The glass-transition temperature Tg of the slurry is greater than or equal to 300 DEG C, the stripping force with a copper foil is greater than or equal to 1.1 N / mm, the slurry can be directly used for preparing a non-adhesive two-layer flexible copper-clad plate, and the problem that the traditional TPI is insufficient in adhesive property and difficult to consider the heat resistance at the same time is solved.