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An electronic cigarette has a power device (1), a sensor (2), an atomizing core component and a liquid storage component (3). The atomizing core component includes an electric heater (5) and a liquid permeating component (6). The electric heater (5) has a through hole (51), the liquid storage component (3) has a channel (31), and the sensor (2) is connected with the through hole (51) and the channel (31) to form an airflow loop by the auxiliary air inlet. The liquid permeating component (6) is directly sleeved on the electric heater (5), so that the cigarette can adequately heat gasified smoke with uniform small drops. The electric heater (5) and the liquid storage component (3) are connected with the through hole (51) and the channel (31), so that the vapor generated by the atomizing process can be cooled.

The present invention relates to a method for continuous production of a water-absorbent resin by use of an continuous polymerization device having a charge part of a monomer aqueous solution; an endless belt on which the monomer and a hydropolymer formed are conveyed; and a discharge part of the hydropolymer, wherein the continuous polymerization device has side walls and a ceiling, and the space ratio in the device represented by the equation, “space ratio in the device=B / A”, is in the range of 1.2 to 20. In the equation, A is a maximum cross-sectional area (cm2) of the hydropolymer during the polymerization in the width direction of the endless belt, and B is a maximum cross-sectional area (cm2) of the space between the endless belt of the continuous polymerization device and the ceiling of the continuous polymerization device in the width direction of the endless belt.

An atomizing electronic cigarette has an atomizing core component and a liquid storage component, including an electric heater. The electric heater may have a through hole aligned with a channel passing through the liquid storage component. the cigarette can heat and uniformly vaporize liquid from the liquid storage component, with the user inhaling the vaporized liquid. The vapor generated by the atomizing process may be cooled as it flows through the channel.

The present invention relates to a class of molecules specified as novel multipurpose antibody derivatives. This class of molecules is created by heterodimerization of two constituting components. Heterodimerization is obtained by the specific heterotypic interaction of a chosen VH-CH1 combination of immunoglobulin domains, with a chosen VL-CL combination of immunoglobulin domains. The appropriate VH and VL domains in the VHCH1 and VLCL context, a binding specificity can be constitituted by the heterodimerization scaffold itself. One or both of the comprising VHCH1 and VLCL chains can thus be extended at either the N- or the C-terminus or both with other molecules, such as a toxin polypeptide, an enzyme, a hormone, a cytokine, a signaling molecule, or a single chain linked Fv fragment with the same or a different specificity.

An applicator for applying functional substances, such as cosmetic powder, food color marking, India ink effect marks, or drugs into human skin, having a base, a plurality of microneedles fixed to and projecting from the base a distance only sufficient to penetrate into the stratum corneum or dermis, with the microneedles being of a material that is capable of disintegration and dispersion into the stratum corneum or dermis, such as maltose. The needles contain the functional substance for delivery into the stratum corneum or dermis. The microneedles are of a length approximately 0.5 to 500 μm when used to apply a functional substance to the stratum corneum, or are of a length of approximately 500 to 5,000 μm when used to apply a functional substance to the dermis.

The present invention relates to transgenic non-human animals that are engineered to contain human immunoglobulin gene loci. In particular, animals in accordance with the invention possess human Ig loci that include plural variable (VH and Vκ) gene regions. Advantageously, the inclusion of plural variable region genes enhances the specificity and diversity of human antibodies produced by the animal. Further, the inclusion of such regions enhances and reconstitutes B-cell development to the animals, such that the animals possess abundant mature B-cells secreting extremely high affinity antibodies.

An array of photovoltaic (PV) module(s) is arranged in series and / or parallel electrical connection to deliver direct current electrical power to an electrolyzer to produce hydrogen. The electric power is delivered by the array at its maximum power point (Vmpp) to deliver Ioper at Voper for the electrolyzer. The arrangement of the PV modules in the array, or the arrangement of cells in the electrolyzer, is continually monitored and controlled by an automatic controller system to operate the PV and electrolyzer systems at or near their respective maximum efficiencies. A DC-DC converter may be used to adjust the Vmpp to the operating voltage of the electrolyzer.

A biomarker generator system for producing approximately one (1) unit dose of a biomarker. The biomarker generator system includes a small, low-power particle accelerator (“micro-accelerator”) and a radiochemical synthesis subsystem having at least one microreactor and / or microfluidic chip. The micro-accelerator is provided for producing approximately one (1) unit dose of a radioactive substance, such as a substance that emits positrons. The radiochemical synthesis subsystem is provided for receiving the radioactive substance, for receiving at least one reagent, and for synthesizing the approximately one (1) unit dose of a biomarker.

A method for producing methane (69) from a carbonaceous (22) material includes conveying pulverized carbonaceous material (28) entrained in an inert carrier fluid, such as carbon dioxide (36), into a reactor (34). The reactor (34) includes a vortex region (72) for receiving hydrogen gas (38) and imparting a swirling motion to the hydrogen gas (38). The pulverized carbonaceous material (28) is exposed to the swirling stream of hydrogen gas (38) in a first reaction zone (114) within the reactor (34) to form an exit gas (40) that includes methane (69). Remaining unreacted carbonaceous material (28) is further exposed to the hydrogen gas (38) in a second, low velocity, reaction zone (120). The methane rich exit gas (40) is subsequently extracted from the reactor (34) for further processing.

A Cooperative Help Assistance (CHA) system and method provide real-time user assistance for one or more windows-based Graphic User Interface (GUI) applications or a single application's different subsections such as web pages, running concurrently in any operating system. The CHA System enables the development of an informative assistance object independently from the original source code or development environment of the target Host Application. The assistance object can be selected by any number of user interfaces from sophisticated inference driven interactive interface search tools or categorized lists. By intercepting and monitoring user actions on a Host Application, the CHA system performs intelligent assistance in the context of the target host application program. Utilizing a Host Application Model, the CHA System and method dynamically assemble many elements in real-time or just-in-time to produce assistance sequences or elements very efficiently without having to code every interface path permutation. Paths can be dynamically generated from the Host Application Model, which enables a real-time module to offer intelligent, contextual assistance as well as real-time construction of automated, accelerated CHA Sequences or Procedures that require little or no user interaction. All assistance and information are processed and expressed by an extensive multitasking, multimedia subsystem for two dimensional (2D) and real-time three-dimensional (3D) application interfaces, which greatly enhances and extends the effectiveness of any explanation or material expression. The production of Assistant Sequences is facilitated by the Host Application Model and 2D and 3D GUI “drag and drop” interface tools.