The invention discloses a simulating PCB intelligent test system which is based on nerve network, which includes main control PC machine, processor, storage, communication circuit, function signal generator, multi-channel sampling switch matrix, sequential circuit, decoding circuit, A/D converter, sampling retainer, differential amplifier, function signal generator under the control of processor outputs stimulating signal to the stimulating node of the tested circuit, the responding signal of the tested circuit is transmited to the processor by multi-channel sampling circuit, then is transmitted to the main control PC machine by communication circuit, the main control PC machine treats the sampling signal with wavelet packet transform de-noising treatment, and with principal component analysis and normalization processing for obtaining fault feature vector; the fault feature vector is inputted into the trained BP nerve network, the output of the BP nerve network is fault type. The invention can position the PCB test fault to the component level effectively, and improve the scalability of system greatly with the simple and effective test method of CMOS switch array.