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19264results about How to "Reduce testing costs" patented technology

Apparatus and method for prediction and management of participant compliance in clinical research

A system for developing and implementing empirically derived algorithms to generate decision rules to determine participant noncompliance and fraud with research protocols in clinical trials allows for the identification of complex patterns of variables that detect or predict participant noncompliance and fraud with research protocol, including performance and enrollment goals, in the clinical trial. The data may be used to overall predict the performance of any participant in a clinical trial, allowing selection of participants that tend to produce useful, high-quality results. The present invention can also be used to monitor participant compliance with the research protocol and goals to determine preferred actions to be performed. Optionally, the invention may provide a spectrum of noncompliance, from minor noncompliance needing only corrective feedback, to significant noncompliance requiring participant removal from the clinical trial or from future clinical trials. The algorithms and decision rules can also be domain-specific, such as detecting non-compliance or fraud among subjects in a cardiovascular drug trial, or demographically specific, such as taking into account gender, age or location, which provides for algorithms and decision rules to be optimized for the specific sample of participants being studied.
Owner:ERESTECH

Device for detecting surface shape of optical aspheric surface by sub-aperture stitching interferometer

The invention relates to a device for detecting a surface shape of an optical aspheric surface by a sub-aperture stitching interferometer, which comprises an interferometer, a transmission sphere, an adjusting mechanism, a numerical control device and a computer, wherein parallel light emitted by the interferometer is changed into a standard spherical wave through the transmission sphere; the computer controls the action of the adjusting mechanism by the numerical control device to adjust the relative position of the interferometer and an aspheric surface to be detected so that the standard spherical wave is incided to each sub-aperture of the detected optical aspheric surface sequentially and returns to the interferometer; and the computer extracts phase distribution data of each sub-aperture measured by the interferometer for analysis and processing, and the error distribution of the surface shape of a full aperture of the detected optical aspheric surface is obtained by a stitching algorithm. The device broadens horizontal and vertical dynamic range tested by the interferometer, can detect surface shapes of large-aperture concave and convex aspheric surfaces and an off-axis aspheric surface in high resolution and high precision without other auxiliary optical elements, and has low testing cost and short construction period.
Owner:CHANGCHUN INST OF OPTICS FINE MECHANICS & PHYSICS CHINESE ACAD OF SCI

Soil slope water flow erosion resistance simulation test method and device

The invention relates to a soil slope water flow erosion resistance simulation test method and device. The device comprises a liftable slope simulation device, a sheetflood scouring simulation device, a water and soil collecting device, a flow velocity determining device and a slope surface form camera device. According to the test method, the water flow is controlled, surface flow and seepage are formed, and sheetflood water, seepage water and sediment quantity formed by scouring slopes by sheetflood water are collected. The flow, the flow velocity, the erosion depth, the sand yield and the like of the water flow are measured quantitatively. Compacted soil is soaked in water until saturation for simulation, the efficiency of an indoor simulation test on slope scouring is improved, the test period is shortened, the test result proves the maximum depth of a slope erosion gully and the change rule of the sand yield with time, discloses the relation between the water flow erosion capacity of catchment behind slopes and the slope length, gradient and time and provides a basis for prediction of the water flow erosion scale and the need of slope protection and reinforcement. The device is simple in structure, convenient to operate and suitable for measurement of soil mechanics parameters of slope soil mass.
Owner:CHANGSHA UNIVERSITY OF SCIENCE AND TECHNOLOGY

MiRNA with cell corpuscule as vector and preparation research approach thereof and application

The invention discloses micro ribonucleic acids (microRNA, miRNA) carried by cell microparticles (Microparticle, MP), a method for preparing the same, and application thereof in the technical field of biotechnological pharmacy. The invention provides a combination of the micro ribonucleic acids for evaluating the physiological and / or pathological states of a participant, and the combination contains all the micro ribonucleic acids which exist stably in serum / plasma particles of the participant and are detectable. At the same time, the invention provides an experimental method for preparing the cell microparticles containing specific micro ribonucleic acids and using the cell microparticles to perform gene-level regulation and control as well as modification on other cells and tissues. The combination and the method can be used for detecting and treating various diseases, including the aspects of the diagnosis and the differential diagnosis of various tumors, various acute and chronic infectious diseases and other acute and chronic diseases, the prediction and the curative effect evaluation of the occurrences of disease complications and the recurrences of malignant diseases, as well as the active ingredient screening, the efficacy evaluation and the judicial authentication of drugs, the detection of prohibited drugs and the like; besides, the combination and the method have the advantages of wide detection pedigree, high sensitivity, low detection cost, convenient available material, easy storage of samples and the like.
Owner:NANJING UNIV

Test device for simulating and testing thermal fatigue failure of high-temperature part in real time

The invention belongs to the field of high-temperature part detecting equipment, in particular to a test device for simulating and testing the thermal fatigue failure of a high-temperature part in real time. The device mainly comprises a high-temperature gas two-way heating system, a real-time temperature testing and collecting system, a cooling system, an ARAMIS non-contact three-dimensional deformation test system, a PCI-2 AE non-destructive detection system, a 1260+1296-type material electric property AC impedance spectroscopy test system, a test control platform and the like. The device can simulate the thermal fatigue work environment of alternating temperature cycle in a high-performance aircraft engine, and synchronously realize the real-time testing and the analysis to the sample temperature, temperature gradient, surface morphology image evolution, three-dimensional deformation field, three-dimensional displacement field, interfacial oxide layer and thickening law, thermal fatigue crack initiation and propagation, cooling gas flow and other data. The device can provide an important experimental platform for effectively evaluating the fatigue failure process and the failure mechanism of the high-temperature part in the high-temperature thermal cycle environment.
Owner:XIANGTAN UNIV

Performance test platform and method for multi-rotor unmanned aerial vehicle

ActiveCN105083588AFlexible swingAccurate and reliable performance indicatorsAircraft components testingFlight vehicleEngineering
The invention discloses a performance test platform and method for a multi-rotor unmanned aerial vehicle. The test platform comprises a base, a stand column, a top frame, a performance test instrument and a calculation processing center; the bottom of the stand column is connected to the base through a ball-head universal bearing, and the top of the stand column is connected to the top frame through a ball-head universal bearing; the top frame is hung on an external rigid body through an elastic inhaul cable; a rack of the multi-rotor unmanned aerial vehicle is provided with a sleeving ring arranged on the stand column in a sleeving mode; the performance test instrument comprises an on-vehicle test instrument body which is arranged on the multi-rotor unmanned aerial vehicle and used for testing flight attitude information and work condition information of the multi-rotor unmanned aerial vehicle and a ground test instrument body which is arranged on the test platform and used for testing external response information of the multi-rotor unmanned aerial vehicle; the calculation processing center comprises a data collecting unit and a data analyzing unit. The test platform is simple in structure, good in flexibility and capable of accurately testing multiple performance indexes of the aerial vehicle.
Owner:SOUTH CHINA AGRI UNIV

Full-automatic biological chips detection system

The invention discloses a full automatic biochip detection system belonging to the clinical detection field of multi-marker biochips. The system adopts modular structure and comprises an automatic sample processing module, a reaction washing module, a detection module, a Tip head storage module, a reagent storage module, a biochip storage module, a sample storage module, a system base, an electric control box and a computer, the electric control box and all the modules are operated under the control of software, so as to realize the automatic sampling, the sample adding, the reaction, the washing, the detection and other processes. All the modules can work independently and can also be combined together and matched for work. The full automatic biochip detection system can overcome the shortcomings of the existing biochip detector and reduce the errors caused by human operation, and has stable and reliable detection result and good flexibility, so that the full automatic biochip detection system can not only greatly improve the detection efficiency, but also can be conductive to the accuracy of the detection result; the system has simple operation, therefore, the system is not only applicable to the scientific research and the applications of laboratories and hospitals, but also can be used for large-scale sample screening of large-scale hospitals and blood stations.
Owner:上海裕隆生物科技有限公司

Virtual oscillating table detection signal processing method and equipment thereof

The invention relates to a vibration table detection instrument field. In order to overcome the defects of the prior art, a signal processing approach is designed to allow a virtue instrument to be applied to the measurement field and an instrument suitable for measurement is designed accordingly on the basis of the signal processing approach. More particularly, the invention relates to a virtual vibration table detecting signal processing method and the instrument. The method comprises the processes: (1) the acceleration value of the vibration table is collected and converted into electric signals; (2) the signal is conditioned by a signal conditioning instrument; (3) the conditioned signal is collected by a data collecting card and transmitted to a computer; (4) the signal is preprocessed by the computer; (5) the preprocessed signal is discrete Fourier transformed and digital signal frequency domain filtered; (6) in the end, a speed component is output after the signal is integrated for one time; a displacement component is output after the signal is integrated for two times. The detection instrument comprises an acceleration sensor, a signal conditioning instrument, a data collecting card and a computer.
Owner:广州市计量检测技术研究院

Sensing method of optical-fiber Bragg grating laser device

The invention relates to a sensing method with an optical-fiber Bragg grating laser device. An optical-fiber Bragg grating is used as a reflector of the resonant cavity, an active optical fiber capable of generating sufficient gains is added, and a double wavelength/multiple wavelength optical-fiber Bragg grating laser device is formed under the action of a pump light source and used as a sensor. When the outside strain, temperature and other physical quantities act on the sensing system, the beat signal frequency among the double wavelength or multiple wavelength laser can shift, and counter stress, temperature and other physical parameters can be measured precisely by detecting the beat signal frequency information. The invention has the advantages of simple manufacture, stable and reliable operation, stable measurement result and high precision, and is free from the interference of light intensity, polarization and other optical information quantities. The multipoint distribution sensing measurement can be realized in a frequency-division multiplexing mode. An electrooptical modulator is added before the spectrum analyzer starts detection so as to randomly adjust the beat signal frequency, thereby greatly reducing the spectral range of the spectrum analyzer and reducing the detection cost.
Owner:NANJING UNIV

Multi-field coupling true triaxial test system and experiment method implemented by same

The invention discloses a multi-field coupling true triaxial test system and an experiment method implemented by the same. The multi-field coupling true triaxial test system is characterized by comprising a true triaxial double-cavity pressure chamber (1), an axial loading system (2), a confining pressure/back pressure loading system (3), a temperature control system (4), a permeation control system (5), a gas loading system (6), a bending element experiment system (7) and a computer (8). The multi-field coupling true triaxial test system and the experiment method have the advantages that stress fields and seepage fields are controlled, and accordingly simulation research can be carried out on seepage anisotropy of rock and soil mass; influence of environmental factors on freezing nucleusor frozen soil samples can be simulated under the effects of temperature fields, the seepage fields and the stress fields; research can be carried out on the physical and mechanical properties of unsaturated frozen soil under the effects of the temperature fields and the stress fields; simulation research can be carried out on change of the physical and earth properties of sediments in generationand decomposition procedures of natural hydrates under multi-field coupling conditions, and simulation research can be carried out on mutual displacement effects between hydrate gas in the sediments and underground water; simulation research can be carried out on the physical and mechanical properties of unsaturated soil under the multi-field coupling conditions.
Owner:南京泰克奥科技有限公司

Human mycoplasma pneumoniae gold-marked silver-stained immunochromatographic assay kit and preparation method and application thereof

The invention provides a human mycoplasma pneumoniae gold-marked silver-stained immunochromatographic assay kit and a preparation method and application thereof. The assay kit comprises a detection card and a silver-stained sensitivity-enhanced pad, wherein the detection card is composed of a bottom plate, a sample pad, an absorbent pad, a conjugate pad and a detection layer; the conjugate pad is coated with a colloidal gold-marked polyclonal antibody mixture of colloidal gold marked rabbit anti-human mycoplasma pneumoniae P1 protein and P30 protein; the detection layer is composed of a solid phase nitrocellulose membrane with a detection line and a quality control line; the detection layer is bonded on the bottom plate, the conjugate pad and the absorbent pad are partially overlapped with the detection layer respectively and are bonded with the detection layer and the bottom plate respectively; the sample pad and the conjugate pad are partially overlapped to be bonded with the conjugate pad and the bottom plate respectively; and the silver-stained sensitivity-enhanced pad consists of a AgNO3 pad and a restoring pad. The human mycoplasma pneumoniae gold-marked silver-stained immunochromatographic assay kit can effectively improve the detection sensitivity of the human mycoplasma pneumoniae, has the strong specificity and has the high application value in the aspects of clinical diagnosis of human mycoplasma pneumoniae, etiology identification, epidemiological investigation and the like.
Owner:HUBEI UNIV OF TECH +1

Manufacturing method of simulation fracture for fractured rock mass seepage test

The invention discloses a manufacturing method of a simulation fracture for a fractured rock mass seepage test. The manufacturing method comprises the steps of drawing a fracture digitized profile curve, constructing a fracture three-dimensional model, making a fracture plate through 3D (three-dimensional) printing, making a fracture test piece casting model and performing casting and maintenance of a fracture test piece, specifically, through digitizing a rock structural surface joint roughness profile curve, drawing the fracture three-dimensional model on the basis of CAD (Computer Aided Design) software, making the fracture plate satisfying JRC value fluctuation by adopting a 3D printing technology, making the fracture test piece casting model by combining the fracture test piece, forming by using cement mortar to cast, and making the fracture test piece by performing maintenance in a cement test piece maintenance box for 28 days. The manufacturing method has the beneficial effects: the manufacturing method of rock rough fracture analogue simulation which is easy in observing, simple in manufacturing, convenient in testing, convenient for adjusting fracture opening, and capable of truly and accurately reflect rock mass fracture structural surface roughness is provided, the working procedures are simple and clear, the manufacturing duration is short, economy and efficiency are realized, the accuracy is high, and the adaptability is good.
Owner:HOHAI UNIV

Delamination propagation behavior simulation method of composite material multidirectional laminated plate on basis of cohesion model

The invention relates to a delamination propagation behavior simulation method of a composite material multidirectional laminated plate on the basis of a cohesion model. The method includes the following steps that (1) a geometric model is built according to structural parameters of a composite material multidirectional laminated plate test piece, (2) key parameters capable of reflecting interfacial behaviors are calculated, and material attributes are respectively set, (3) meshing is carried out on the geometric model of the composite material multidirectional laminated plate test piece, a module is assembled, and a three-dimensional finite element model is built, (4) a load and boundary conditions of the finite element model are determined according to practical situations and the load state of a composite material structure, (5) the finite element model based on the cohesion model is calculated and analyzed, a load displacement curve of a loading point is extracted, delamination propagation behaviors of the composite material multidirectional laminated plate are simulated to obtain the largest load value of the load displacement curve, and damage behaviors of the multidirectional laminated plate are predicted.
Owner:BEIHANG UNIV
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