The invention discloses a soft-shelled turtle feed for preventing and treating parotitis as well as a preparation method thereof. The soft-shelled turtle feed for preventing and treating parotitis is prepared from the following raw materials in parts by weight: 20-30 parts of sweet corn protein powder, 10-15 parts of wheat germ powder, 5-10 parts of sesame seed meal, 10-15 parts of alfalfa hay, 8-12 parts of wheat middling, 30-40 parts of marine fish powder, 6-9 parts of snail powder, 3-5 parts of dry sea sedge, 2-3 parts of radices trichosanthis, 1-2 parts of chrysanthemum leaves, 2-3 parts of plantain herb, 0.5-1.5 parts of centella, 1-2 parts of phaseolus radiates, 1.5-2.5 parts of hibiscus mutabilis, 2-3 parts of purslane and 1-2 parts of phagostimulant. The chrysanthemum leaves, plantain herb, centella, phaseolus radiates, hibiscus mutabilis and purslane are added to the feed provided by the invention on the basis of guaranteeing the nutrition requirement of soft-shelled turtle growth, and can play effects of clearing away heat and detoxifying, dispelling wind, removing stasis, fighting bacterium, diminishing inflammation, relieving pain and stopping blood, improve the disease resistance of soft-shelled turtles, can effectively prevent and treat parotitis of soft-shelled turtles, guarantee the healthy growth of soft-shelled turtles, improve the survival rate of soft-shelled turtles, reduce the cultivation hazard, and improve the economical benefit of farmers.