357 results about "Aconitum" patented technology

The present invention provides a composition of transdermally administered alkaloids from aconitum plant for ameliorating pain and inflammation. In one aspect, an aconitum alkaloid is delivered in a sufficient amount to achieve and maintain a blood plasma aconitum alkaloid level of about 0.5 ng/mL to about 400 ng/mL. Aconitum alkaloids may be delivered by themselves, or in combination with other elements, such as additional analgesics, other drugs, or positive health promoting substances. Various formulations for the transdermal delivery of aconitum alkaloids are disclosed, and may include selected penetration enhancers.

The invention discloses a pharmaceutical composition for killing termites. Termites are a very harmful pest, which has caused serious harm and major economic losses to various sectors and fields of the national economy. Traditional termite-killing medicines are made of highly toxic chemicals, which cause serious pollution to the environment, and cannot completely kill termites fundamentally. The present invention adopts Aconitum aconitum, Aconitum aconitum, Realgar, Banxia, ​​Dafengzi, Torreya chinensis, capsicum and talcum powder as raw materials, which can be made into various dosage forms such as powder, granule and tablet, and has the advantages of safety, non-toxicity, quick effect, and killing effect. Features such as complete termite eradication. The medicine source of the invention is rich, the preparation method is simple and easy, and the cost is low.

The invention provides a preparation method of a compound biological pesticide fertilizer special for peach trees which comprises the following components in parts by weight: 40-60 parts of greenhouses garbage, 10-15 parts of fallen leaves, 10-15 parts of snakegourd fruit vines, 10-15 parts of edible mushroom chaff, 7-9 parts of sheep manure, 10-12 parts of sugar residues, 16-18 parts of humic acid ammonium phosphate, 10-12 parts of monoammonium phosphate, 8-9 parts of superphosphate, 9-11 parts of urea, 10-12 parts of potassium sulfate, 15-18 parts of slags, 14-16 parts of pig furs, 11-13 parts of bamboo charcoals, 2-4 parts of EM strains, 3-5 parts of mint leaves, 3-5 parts of Anemone hupehensis, 3-5 parts of neem, 4-6 parts of Tripterygium Wilfordii, 7-9 parts of eucalyptus leaves, 8-10 parts of hives, 4-6 parts of Aconitum, 5-7 parts of lotus leaves, 0.7-1.2 parts of boric acid, 0.8-1.2 parts of zinc sulfate, 0.6-0.8 part of manganese sulfate, and an appropriate amount of Baeckea frutescens oil. The pesticide fertilizer provided by the invention can improve the utilization rate, carry out primary fertilization, effectively and slowly release the fertilizer, reduce the fertilizing frequency, lower the fertilizer cost and enhance economic benefits.

The present invention provides a composition of transdermally administered aconitine alkaloids for ameliorating pain and inflammation. In one aspect, an aconitine alkaloid is delivered in a sufficient amount to achieve and maintian a blood plasma aconitine alkaloid level of about 0.5 ng/mL to about 400 ng/mL. Aconitine alkaloids may be delivered by themselves, or in combination with other elements, such as additional analgesics, other drugs, or positive health promoting substances. Various formulations for the transdermal delivery of aconitine alkaloids are disclosed, and may include selected penetration enhancers.

The invention discloses preparation and application of acylate (a compound structure is shown in figure) of natural napelline type diterpenoid alkaloids in Aconitum plant aconite, which belong to the technical field of medicine synthesis of medicine and pesticide. The method for preparing the acylate of the napelline type diterpenoid alkaloids comprises the following steps: a napelline type diterpenoid alkaloid compound in aconite is taken as a raw material to be stirred to react with an acylating reagent, namely acyl chloride or acid anhydride at a temperature of between 0 and 40 DEG C, the pH value is adjusted to be between 8 and 10 after the reaction is finished, the reduced pressure distillation is performed after the extraction, and the acylate of the napelline type diterpenoid alkaloids is obtained through recrystallization or column chromatography. The acylate of the napelline type diterpenoid alkaloids can be applied to agricultural insecticides, and can also be used for the development of anti-tumor drugs, anti-inflammatory analgesics, antiarrhythmic drugs and so on. In a formula, R1 and R2 are hydrogen, hydroxy or acyl (at least one of R1 and R2 is acyl); and R3 is alkyl containing 1 to 4 carbon atoms.

The invention discloses a fertilizer with natural insecticidal effect and a preparation method thereof and belongs to the technical field of fertilizer preparation. The fertilizer comprises, by weight, root bark of Chinaberry, pyrethrum, Paulownia leaf, garlic, lightyellow Sophora root, tobacco waste, Celastrus angulatus seed, Aconitum soongoricum tuber, waste residue, apple snail powder, biological bacteria, boron salt, ferric salt, zinc salt, manganese salt, copper salt, a water-retaining agent, a conditioner, and a dispersant. The fertilizer is prepared in the steps such as crushing, extracting, filtering, concentrating, fermenting, granulating, drying and cooling. The fertilizer is effective in preventing disease and pest damage, has balanced nutrition and is also capable of improving soil environment, promoting quick and healthy growth of crops, shortening a growth cycle, increasing crop yield and lowering production cost.

The invention discloses an environmentally-friendly Chinese herbal medicinal biological pesticide. The pesticide comprises, by weight, 1-10 parts of a synergist, 5-20 parts of Herba Taraxaci, 4-10 parts of purslane, 6-9 parts of Siberian Cocklour Fruit, 10-15 parts of pomegranate rind, 11-15 parts of Artemisia argyi, 20-30 parts of Cannabis sativa L., 10-20 parts of Chloranthus serratus, 15-20 parts of Artemisia annua L., 20-30 parts of tobacco, 10-15 parts of Phytolacca acinosa Roxb, 10-20 parts of Aconitum carmichaeli Debx., 12-18 parts of Herba Houttuyniae, 5-18 parts of Andrographis paniculata, 4-10 parts of camphor, 50-70 parts of Common Threewingnut Root and 100-150 parts of water. The environmentally-friendly Chinese herbal medicinal biological pesticide is a novel pesticide having the advantages of high effectiveness, pertinence, environmental protection, no secondary toxicity, no residual, no pollution, ecologic balance maintenance and no nuisance, is an important guarantee for realizing the ecologic agriculture, the green ecologic agriculture and green enterprises, and has a broad prospect.

The invention discloses a standardization planting technology of cold-highland-area aconitum vilmorimianum kom. The standardization planting technology includes the steps of 1, planting area selecting; 2, soil preparing; 3, seed selecting; 4, standardization cultivating; 5, field managing; 6, disease and pest preventing; 7, harvesting. By means of the planting technology of cold-highland-area aconitum vilmorimianum kom, a regular effect and a reasonable effect are achieved, the yield can be increased, quality can be guaranteed, and high-quality raw materials can be provided.

The invention discloses a biopesticide for vegetables and a preparation method of the biopesticide. The biopesticide is mainly prepared from the components in parts by weight as follows: 1 part of toyocamycin, 50-70 parts of common threewingnut roots, 60-80 parts of graceful jessamine herb, 40-60 parts of aconite, 50-70 parts of coptis chinensis, 40-60 parts of purslane, 30-50 parts of herba houttuyniae, 40-60 parts of common andrographis herb and 2-4 parts of a suspending agent. Compared with common chemical pesticides in the prior art, the obtained biopesticide for the vegetables has the characteristics of good effect and low toxicity and can be used as an ideal environment-friendly agricultural drug for vegetable protection; meanwhile, the toyocamycin is compounded with traditional Chinese medicine extracts, so that the sterilization and insecticidal spectrum can be enlarged, the efficacy can also be improved, and what's more, the problem of drug resistance caused by long-term usage of single pesticides can be solved.

The invention relates to a traditional Chinese medicine composition for treating goose gout. The traditional Chinese medicine composition is prepared from 15-24 parts of poria cocos, 10-13 parts of astragalus membranaceus, 10-12 parts of fourstamen stephania roots, 12-18 parts of cassia twigs, 6-8 parts of aconite, 12-16 parts of radix aconiti carmichaeli, 8-16 parts of rhizoma atractylodis macrocephalae and 8-11 parts of liquorice. The traditional Chinese medicine composition can be made into powder and is prepared in the steps of 1, weighing the traditional Chinese medicinal materials according to a formula; 2, smashing the traditional Chinese medicinal materials and conducting screening with a 40-100-mesh screen; 3, conducting mixing for 5-15 min to generate traditional Chinese medicine powder; 4, subpackaging the traditional Chinese medicine powder in bags with 100-300 g traditional Chinese medicine powder in each bag, so that finished products are obtained. The adopted Chinese herbal medicinal materials can invigorate spleen and replenish qi, warm yang to promote diuresis, warm channel and expel cold, and dispel wind and eliminate dampness, goose gout can be effectively treated, and the cure rate can reach 90.12%.

The invention provides analgesic and antiphlogistic medicines and a micro-needle transdermal administration method for the same. Analgesic and antiphlogistic traditional Chinese medicines with aconitum alkaloid as a representative have the characteristics of long action and non-frequent administration; a micro-needle administration system enables slow release and sustained release of aconitum alkaloid to be realized. A plasma concentration in a range of 0.5 to 500 ng/ml is achieved in 0.5 to 14 h after administration. The invention provides a micro-needle transdermal administration method and system for analgesic and antiphlogistic medicines capable of enhancing pain or inflammation, with aconitum alkaloid included. According to the invention, usage amount of aconitum alkaloid is sufficient to enable a plasma concentration of about 0.5 to 400 ng/ml to be achieved and maintained; administration through skin pricking enables painless administration to be realized, and the medicines themselves do not cause direct irritation or damage to skin surface.

The invention relates to a traditional Chinese medicine composition of a medicinal pillow for treating cervical spondylosis in the field of bedding health protection products. The traditional Chinese medicine composition comprises the following raw materials in weight portion: 20 to 30 portions of angelica, 20 to 30 portions of chuanxiong rhizome, 15 to 30 portions of dragon blood, 20 to 40 portions of mulberry branch, 20 to 30 portions of safflower, 15 to 25 portions of boswellin, 15 to 25 portions of myrrh, 20 to 30 portions of radix salviae miltiorrhizae, 15 to 20 portions of asarum herb, 25 to 30 portions of Chinese clematis, 20 to 30 portions of earthworm, 20 to 30 portions of calamus, 20 to 30 portions of ledebouriella root, 20 to 30 portions of American lopseed, 15 to 25 portions of prepared aconitum Chinese Paxton, 15 to 20 portions of camphor, 20 to 30 portions of pawpaw, 15 to 25 portions of panicled swallowwort root, 30 to 40 portions of argyi leaf, and 10 to 20 portions of borneol. The traditional Chinese medicine composition which has reasonable crude drug selection and accurate compatibility has the effects of stimulating blood circulation and removing blood stasis, unblocking channels and relieving pains, dispelling wind evils and eliminating dampness, and refreshing and restoring consciousness. The medicinal pillow has a good curative effect on the nerve root type sympathetic type cervical spondylosis and has assistant therapeutic action on migraine and neurasthenia.

The invention discloses a pesticide for preventing and controlling cotton anthracnose, and belongs to the technical field of agriculture. The pesticide comprises a seed dressing agent and a leaf surface spraying agent; the seed dressing agent is composed of 25% carbendazol wettable powder, 40% azoxystrobin wettable powder and 50% dimethomorph wettable powder; the leaf surface spraying agent is composed of 1.8% abamectin wettable powder, 50% sporgon wettable powde, 50% dimethomorph wettable powder and traditional Chinese medicine bactericide; the traditional Chinese medicine bactericide is prepared from, by weight, 10 parts of pokeberry roots, 10 parts of aconite, 10 parts of ailanthus, 10 parts of purple perilla, 20 parts of tobacco and 20 parts of garlic. According to the pesticide for preventing and controlling the cotton anthracnose, Chinese herbal medicine ingredients and chemical preparations are compounded for use, the effect is better, preparation and usage are easy, the effect of preventing and controlling cotton starscream diseases is better, and the control effect can almost reach 100 percent.

The invention provides a compound shown as formula I in the specification or salt thereof. Specifically, R1 is selected from hydrogen, C1-C8 alkyl, C1-C8 alkoxy, halogen and -OC(O)R2; and R2 is selected from C1-C8 alkyl. According to the invention, the compound mithracitine separated from an indaconitone processed product not only does not cause arrhythmia, but also has excellent treatment effecton arrhythmia, can be used for preparation of drugs treating arrhythmia, and also can greatly reduce the toxicity of aconitum drugs containing indaconitone, thus having good application prospects.

The invention discloses a special herbicide used in a nursery garden and a preparation method thereof, and belongs to the technical field of pesticides. The herbicide is prepared from the following raw materials in parts by weight: 15 parts of glyphosate, 2 parts of trifluralin, 1 part of imazethapyr, 0.1 part of metsulfuron-methyl, 1 part of a bactericide, 3 parts of auxiliaries and 80 parts of water, wherein the glyphosate is 41% water-based glyphosate, the trifluralin is 480g/L emulsifiable concentrate trifluralin, the imazethapyr is 70% particles and the metsulfuron-methyl is 60% particles; the bactericide is prepared by performing water extraction on garlic, veratrum nigrum, aconitum rotundifolium, fraxinella, elderberry, ailanthus and pokeberry root in a weight ratio of 10 to 2 to 2 to 2 to 2 to 5 to 10. The weeding active ingredients are combined for completely preventing the growth of weeds when being applied to seedling in the nursery garden, and meanwhile, plants cannot be influenced. The traditional Chinese medicine bactericide is added to the special herbicide, so that the incidence of soil-borne diseases and various root rot can be obviously reduced during weeding.

The invention discloses a yellow aconite hair root and its acquisition method. The yellow aconite hair root provided by this invention is obtained by selecting yellow aconitic organ as explant materials, performing transfection by hair root agricillin and culturing the hair root. The yellow aconite hair root obtained by this invention can reproduce by fluid culture method, the reproductive speed is quick, the period of production is short (about 40 days or so), and it can not be influenced by the natural condition, which can carry out the intensifited industrial production and can overcome the defects that the speed of reprothropology is slow, the growing cycle is long, the output is low and the hereditary stability is weak in artificial planting of yellow aconite hair root; the medicinal components in hair root-the guanfu base A is of high content, which has wide application foreground and utilization value.

The invention discloses a method for breeding aconite which comprises the following steps of: soaking seed with GA3 solution, sowing seeds, managing after sowing, transplanting, and the like. Before the aconite seed is sown, the aconite seed is soaked in a GA3 solution having a concentration of 400mg/L to 1000 mg/L, in order to obviously promote the germination percentage and the germinating energy of the aconite seed, increase the fresh weight of the over-ground part of the aconite seedling, and emerge rapidly and orderly. The growing of the aconite seedling can be boosted and the earthnut diameter can be increased by using a proper sowing and managing method so as to decrease the breeding cost of the aconite and promote the yield of the aconite.

The invention provides a method for taking Aconitum Chinese medicine as raw material to prepare mono-ester aconitum alkaloids. The method is as follows: radic aconite kusnezoffii preparata and radix aconiti praeparata of the Aconitum Chinese medicine is quenched by ethanol; alcohol precipitation is performed by anhydrous alcohols and then extraction is performed; extractum is prepared by lower solution and then prepared into alkaline water solution with the pH between 7.5 and 9.5; the solution is placed in a water bath at a temperature of 100 DEG C for 3 hours; chloroform is used for extraction after cooling of the solution; the extracted chloroform solution is evaporated to prepare extractum and then the mono-ester aconitum alkaloids are obtained. The extraction and separation effects are good through electro-spray mass spectrometric detection. The gross production rate of the mono-ester aconitum alkaloids calculated is over 0.21 percent.

A traditional Chinese medicine for refreshing the brain and improving intelligence and a production process thereof relate to a traditional Chinese medicine. Its formula is composed of: Chuanxiong 0.2-0.6g, Chrysanthemum 0.1-0.4g, Raw Pinellia 0.8-1.2g, Frankincense 0.2-0.5g, Myrrh 0.2-0.5g, Astragalus 0.4-0.8g, Guizhi 0.2-0.5g g, Nanxing 0.1-0.4g, Asarum 0.1-0.4g, Aconitum 0.8-1.2g, Safflower 0.8-1.4g, Paeoniae Alba 0.2-0.5g, Shenjin leather 1.0-1.3g, Fangfeng 0.1-0.4g, Earthworm 0.1-0.4g, Aconite 0.2-0.5g, Woody Fragrance 0.3-0.5g, Angelica 1.0-1.3g, Ginseng 1.0-1.3g, White Mustard Seed 0.1-0.3g, Mildew Spatholobus 0.1-0.3g, Magnet 1.3- 1.6g, Tianma 1.0-1.5g, Panax notoginseng 0.8-1.2g, Achyranthes bidentata 0.7-1.2g, Ephedra 1.2-1.6g, Borneol 1.2-1.6g, Uncaria 0.5-0.8g and Styrax 0.4-0.6g; The invention can dredge meridians and activate collaterals, tonify yang and replenish qi, refresh the brain and improve intelligence, and it is cheap and widely applicable.

The invention discloses a microbial agricultural traditional Chinese medicine pesticide comprising the following components by weight: 5-13 parts of lactobacillus powder, 1-3 parts of nitrobacteria powder, 5-6 parts of nodule bacteria powder, 8-10 parts of monoucleosis powder, 9-13 parts of candida powder, 4-13 parts of rhodococcus powder, 7-13 parts of chrysanthemum, 9-13 parts of hemsleya amabilis, 1-7 parts of antifebrile dichroa, 3-8 parts of snake slough, 3-7 parts of grifola, 5-9 parts of marijuana, 5-8 parts of serrate chloranthus, 5-12 parts of artemisia annua leaf, 1-6 parts of caffeine, 1-10 parts of a synergistic agent, 20-30 parts of tobacco, 10-15 parts of pokeweed, 10-20 parts of aconitum and 100 parts of water. The microbial agricultural traditional Chinese medicine pesticide is a new pesticide which is high-efficiency, purposeful, environmentally-friendly, free of secondary toxicity, residue and pollution, can keep ecological balance, is an important guarantee for realization of ecological agriculture, green ecological agriculture and green enterprise, and has broad prospects.

The invention provides a paddy environmentally-friendly pesticide which is prepared from a botanical insecticide and a special auxiliary agent, wherein the botanical insecticide is prepared from marijuana, serrate chloranthus root, Artemisia annua, tobacco, radix phytolaccae and field thistle, and the formulation of the botanical insecticide is as follows: 25-35kg of marijuana, 10-25kg of serrate chloranthus root, 15-20kg of Artemisia annua, 25-35kg of tobacco, 18-30kg of radix phytolaccae and 7-15kg of field thistle; aconite can be added into the formulation of the paddy environmentally-friendly pesticide, and the addition of the aconite is 5-10kg; and the auxiliary agent is prepared from the following components: 6-10kg of emulsifying agent, 10-15kg of turpentine, 3-5kg of penetrating agent, 0.4-1.5kg of antiseptic agent and 22-28kg of ethanol. The pesticide provided by the invention is prepared by scientifically processing pure natural plants utilized as raw materials, not only is low in toxicity but also has no toxicity residue problem, can not perform secondary killing on birds which are natural enemies of injurious insects and can not cause damage to human, animals and zoology, thus being an efficient, targeted, environmentally-friendly, secondary-toxicity-free, no-residue, no-pollution, nuisanceless and novel pesticide capable of keeping ecological balance, and being an important guarantee for realizing ecological agriculture, green ecological agriculture and green enterprises.

The invention discloses a traditional Chinese medicine, in particular a traditional Chinese medicine composition for treating rheumatoid arthritis and a preparation method thereof. The traditional Chinese medicine composition for treating rheumatoid arthritis is characterized by comprising the following components: aconitum wardii, grass monkshood, Pinellia ternata, rhizoma arisaematis, nux vomica, hindu hatura flower, pseudo-ginseng, dragon's blood, ligusticum wallichii, turmeric, safflower carthamus, corydalis tuber, root of common peony, vinegary armadillo, radix angelica, vinegary frankincense, vinegary myrrh, ginger, camphor and plum blossom borneol. The traditional Chinese medicine is specially used for treating rheumatoid arthritis and a plurality of medicines are matched properly to improve the curative effect by means of inter-synergism or resistance so as to meet the treating requirement of complex condition. The traditional Chinese medicine reduces the adverse reaction, has rapid effect of external treatment, is convenient for external use, safe and reliable and has good treating or symptom relieving effect for rheumatoid arthritis and cervicodynia, omalgia, lumbago and skelalgia. Totally 660 patients are treated and total effective rate reaches 96%.