58 results about "Polygala" patented technology

The invention belongs to the technical field of traditional Chinese medicine fermentation, and particularly relates to a traditional Chinese medicine fermentation composition for regulating sleep as well as a preparation method and application thereof. The traditional Chinese medicine fermented composition for regulating sleep is prepared by fermenting spina date seeds, poria cocos, lily, liquorice, polygala tenuifolia, cortex albiziae, lotus seeds and Chinese yams serving as traditional Chinese medicine raw materials through probiotics. The traditional Chinese medicine raw materials with specific components are selected and subjected to gradient fermentation with specific strains, the prepared traditional Chinese medicine composition is remarkable in sleep adjusting effect, and the level of 5-hydroxytryptamine can be remarkably improved.

The invention provides a fingerprint spectrum and multi-component content determination method of a calamus-far nerve calming mixture, and relates to the field of quality control of traditional Chinese medicines. 31 common peaks are calibrated by establishing a fingerprint spectrum, and 24 common peaks can clearly belong to polygala tenuifolia. Meanwhile, synchronous content determination of seven components including chlorogenic acid, caffeic acid, ferulic acid, liquiritin, 2, 3, 5, 4 '-tetrahydroxy stilbene-2-O-beta-D-glucoside, 3, 6'-dimustard acyl sucrose and rosmarinic acid is realized. The method is good in precision, high in repeatability and stable and reliable in result, the medicine quality can be comprehensively and accurately reflected and controlled, and powerful support is provided for guaranteeing the safety and effectiveness of the calamus-far Ningmind mixture.

The invention discloses health-care deer medicinal liquor and a preparation method thereof. The health-care deer medicinal liquor is prepared from the following raw materials in parts by weight: 80 to 120 parts of Chinese chive seeds, 80 to 120 parts of fructus schisandrae chinensis, 80 to 120 parts of polygala tenuifolia, 80 to 120 parts of fructus alpiniae oxyphyllae, 80 to 120 parts of rhizoma anemones altaicae, 80 to 120 parts of radix cyathulae, 80 to 120 parts of fructus corni, 80 to 120 parts of semen cuscutae, 40 to 60 parts of radix morindae officinalis, 160 to 240 parts of radix ophiopogonis, 160 to 240 parts of radix polygonati officinalis, 480 to 720 parts of mulberries, 30 to 50 parts of lucid ganoderma and 20 to 40 parts of cornu cervi pantotrichum. The invention solves the problems that the existing medicinal liquor preparation process is relatively simple, normal-temperature soaking is generally adopted, deep effective components of medicinal materials are difficult to fully extract, the fusion degree of the effective components and liquor is relatively low, and the final curative effect of the medicinal liquor is reduced.

The invention provides a traditional Chinese medicine composition for treating cerebrovascular diseases and a preparation method and application thereof, and belongs to the technical field of biological medicine. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 8 to 12 parts of rhizoma chuanxiong, 12 to 17 parts of radix paeoniae rubra, 13 to 18 parts of radix salviae miltiorrhizae, 8 to 12 parts of radix polygalae, 10 to 15 parts of rhizoma acori graminei, 27 to 32 parts of radix astragali seu hedysari, 0.3 to 0.7 part of borneol, 0.1 to 0.2 part of musk, 12 to 18 parts of radix angelicae sinensis, 6 to 12 parts of flos carthami, 7 to 12 parts of semen persicae and 5 to 7 parts of radix glycyrrhizae preparata. The traditional Chinese medicine composition disclosed by the invention has the curative effects of tonifying qi and activating blood, dispersing blood stasis and dredging collaterals, and restoring consciousness and inducing resuscitation. The traditional Chinese medicine composition can be combined with a leg electrical stimulation system to efficiently treat cerebral apoplexy hemiplegia and effectively treat vascular dementia, and has an obvious treatment effect on cerebrovascular diseases. The preparation method of the traditional Chinese medicine composition is simple, convenient and rapid, and is suitable for industrial production.

The invention provides a nerve soothing and mind stabilizing pill and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine preparations. The preparation method comprises the following steps: cleaning, infiltrating, cutting, drying, performing high-pressure steam sterilization on genuine medicinal materials such as poria cocos, poria with hostwood, ginseng, polygala tenuifolia, rhizoma acori graminei and the like in a formula of the mind-tranquilizing and mind-tranquilizing pill, mixing and crushing at low temperature to obtain fine powder, adding refined honey to prepare pills, and finally coating with cinnabar powder to obtain the mind-tranquilizing and mind-tranquilizing pill. The contents of polygala-ketone III, 3, 6 '-dimustard acyl sucrose, ginsenoside Rb1, beta-asarone, dehydrotumoic acid, pachymic acid and calcium salt in the prepared nerve-soothing and mind-stabilizing pill are high, the loss of index components in the pelleting process is small, and the dissolution time limit and microbial limit of the pill meet the requirements of Chinese Pharmacopoeia of 2025 edition. The preparation process of the mind-tranquilizing and mind-stabilizing pill is stable, and the prepared mind-tranquilizing and mind-stabilizing pill can effectively improve cognitive impairment, inflammation and oxidative stress injury caused by insomnia.

The invention discloses a medicinal moxa composition for preventing and treating atherosclerosis and suppurative bacterial infection co-disease. The medicinal moxa composition comprises coptis chinensis, radix rehmanniae, polygala tenuifolia, juncus effuses and moxa. The medicinal folium artemisiae argyi composition disclosed by the invention can be used for effectively preventing and treating atherosclerosis and skin suppurative bacterial infection co-diseases through a multi-target synergistic effect. The medicinal moxa composition has the core effects of clearing away heart-fire, inducing diuresis for treating stranguria and promoting blood circulation to remove meridian obstruction, and forms a complete treatment system which uses cold and warm as well as treats both symptoms and root causes by purging fire for removing toxin through coptis chinensis, clearing heat and cooling blood through radix rehmanniae, soothing nerves and promoting intelligence through polygala, inducing diuresis and conducting heat downward movement through juncus effuses and combining moxa floss for warming and dredging meridians, eliminating cold to stop pain, resisting bacteria and diminishing inflammation. By inhibiting inflammatory factors, regulating epithelial cell proliferation and reaction to oxidative stress, regulating fluid shear force, atherosclerosis and Kaposi sarcoma-related herpesvirus infection-related pathways and other mechanisms, the medicinal folium artemisiae argyi composition realizes synergistic prevention and treatment of atherosclerosis and skin infection, and provides a basis for co-disease treatment.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for relieving depression and clearing collaterals and a preparation, a pharmaceutical composition and application thereof. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 6-12 parts of radix bupleuri, 9-15 parts of radix curcumae, 6-12 parts of rhizoma acori graminei, 3-9 parts of fructus gardeniae, 3-9 parts of polygala tenuifolia, 9-15 parts of radix paeoniae rubra and 9-20 parts of cortex albiziae. The traditional Chinese medicine composition provided by the invention can be used for remarkably improving depression-like behaviors of mice with depression, reversing synaptic injury and improving the expression of synaptic associated proteins SYP and PSD-95. The anti-depression mechanism of the traditional Chinese medicine composition is that the traditional Chinese medicine composition has the effects of synergistically inhibiting activation of microglial cells and reducing the level of proinflammatory cytokines such as Tnf alpha, Il1beta and Il6, so that neuroinflammation is remarkably inhibited, and the traditional Chinese medicine composition has the advantages of novel formula, definite mechanism and definite curative effect for treating depression, particularly patients with anxiety and dysphoria symptoms.

The present application belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating cerebrovascular disease and a preparation method thereof. The traditional Chinese medicine composition for treating cerebrovascular disease comprises the following raw materials in parts by weight: 19-24 parts of chuanxiong, 15-20 parts of gastrodia, 8-14 parts of kudzu vine tea, 11-17 parts of San Ye Qing Teng, 3-9 parts of hibiscus flower, 7-12 parts of polygala, and 2-5 parts of licorice. The chuanxiong in the composition has the effects of activating blood and regulating qi, and the gastrodia has the effects of calming wind and stopping convulsion, and both of them are used as monarch drugs. The kudzu vine tea and San Ye Qing Teng are used as minister drugs, the kudzu vine tea has the effect of resolving and dredging collaterals, and the San Ye Qing Teng has the effect of dispelling wind and relieving pain. The hibiscus flower and polygala are both used as auxiliary drugs, and the licorice is used as a guide drug. The licorice can not only harmonize all drugs, but also warm the center and promote drug absorption. The traditional Chinese medicine composition has the effects of activating blood and resolving stasis, dredging collaterals and relieving pain, and soothing the nerves and helping sleep. The composition has good therapeutic effects on stroke and apoplexy.

This invention provides a composition comprising: 5-15 parts by weight of dried plum, 10-20 parts by weight of cinnamon twig, 10-20 parts by weight of ginseng, 3-8 parts by weight of angelica root, 5-15 parts by weight of asarum, 10-30 parts by weight of dried ginger, 5-15 parts by weight of Sichuan pepper, 5-15 parts by weight of phellodendron bark, 3-8 parts by weight of coptis root, 20-40 parts by weight of bitter wine, 20-30 parts by weight of japonica rice, 10-20 parts by weight of honey, 3-8 parts by weight of lily bulb, 40-60 parts by weight of polygonum multiflorum stem, 40-60 parts by weight of monkey head mushroom, 3-8 parts by weight of polygala root, and 5-15 parts by weight of poria cocos (a traditional Chinese medicine composition). Further, the composition comprises: 20-40 parts by weight of hydrolyzed milk protein, 20-40 parts by weight of fish collagen peptide, and 20-40 parts by weight of soybean peptide (a biological product). This invention also provides pharmaceutical preparations (especially pills) comprising the above composition, biological products, and methods for preparing the same. The composition has a significant effect on improving sleep and has broad application prospects.

The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating co-disease of liver depression and spleen deficiency type depressive state and IBS (irritable bowel syndrome). The composition comprises radix pseudostellariae, poria cocos, raw coix seeds, fingered citron, polygala tenuifolia, roasted rhizoma atractylodis macrocephalae, lotus seed pulp, mint, roses, lilies, raw fructus gardeniae, fermented soybeans and raw hawthorn fruits. Liver soothing, depression relieving, spleen strengthening and heart nourishing are taken as core treatment rules, heat clearing, restlessness relieving, digestion promoting and stagnation removing are also taken, and the complex pathogenesis that the two are causal to each other is formed for gastrointestinal dysfunction caused by emotional discomfort. The formula is characterized in that the three internal organs of the heart, the liver and the spleen are treated at the same time, the four methods of tonifying, dredging, clearing and eliminating are used at the same time, balance is achieved between qi regulating and healthy qi supporting, and the formula is suitable for patients suffering from complex heart and body diseases with low mood, anxiety, dysphoria, insomnia, amnesia, abdominal fullness, inappetence, loose stool or loose stagnation.

The invention provides a traditional Chinese medicine compound external preparation for invigorating the kidney and strengthening Yang and a preparation method thereof, belongs to the technical field of traditional Chinese medicine preparations, and aims to solve the problems that the bioavailability of the first-pass effect of existing oral administration is low, and effective components of external ointment are difficult to penetrate through the skin. The preparation is a composite gel containing a penetration enhancer and a temperature-sensitive gel matrix, and the traditional Chinese medicine compound at least comprises various active ingredients of male silkworm moth, centipede, epimedium, rhizoma curculiginis, cistanche, schisandra chinensis, semen cuscutae, polygala tenuifolia, fructus cnidii, semen allii tuberosi, actinolite, sulfur, venenum bufonis, amethyst and borneol. According to the preparation disclosed by the invention, the transdermal permeation rate and the cumulative permeation amount of various active ingredients in the compound are improved in order of magnitude, so that an effective treatment concentration can be ensured to be reached in an in-vitro local or in-vivo system. In clinical application, the traditional Chinese medicine composition has better effect taking speed and treatment effect than external application or oral administration of traditional prescriptions with the same name.

The application discloses a kind of American ginseng compound antioxidant products, is prepared from the following mass fraction components extraction: American ginseng 20-30 parts, 15-25 parts of radix rehmanniae preparata, 20-28 parts of dogwood, 15-25 parts of radix scrophulariae, 15-25 parts of gardenia, 8-12 parts of safflower, 18-22 parts of chuanxiong, 20-26 parts of citrus aurantium, 18-25 parts of alocasia, 10-20 parts of polygala, 16-26 parts of Platycladus branchlet, 15-25 parts of hovenia dulcis thunb, after screening, cleaning, crushing, weighing, alcohol extraction, water extraction, concentration and the like step is made.Compared with prior art, the application obtains the beneficial effect: synergistic effect between components, by tonifying qi and invigorating the spleen, nourishing liver and kidney, clearing heart and detoxifying, promoting blood circulation and qi movement, it has the effect of root and original for senile dementia, using reasonable extraction method is beneficial to the extraction of each effective component;Since the components of the application are non-toxic commonly used medicinal materials, there is no harm to the body after use, and there is no side effect.

The invention discloses granules of a composition containing polygala tenuifolia. The granules further comprise an excipient and an adhesive, wherein the weight ratio of the dry paste powder of the composition to the excipient to the adhesive is (0.5-1.5): (0.5-2.5): (0.01-1), the composition comprises polygala tenuifolia, rhizoma acori graminei and poria with hostwood, the excipient is microcrystalline cellulose, and the adhesive is povidone and / or maltodextrin. The granules improve the compliance of clinical medication of patients, especially elderly patients, and meanwhile, a solution is provided for taste masking of other preparations containing polygala tenuifolia medicine taste related components.

The application discloses a traditional Chinese medicine composition for treating insomnia, anxiety depression and AD, a preparation method and application thereof. The traditional Chinese medicine composition adopts an ethanol extract of raw medicinal materials, and the raw medicinal materials include, by weight, 175-185 parts of polygala root, 160-170 parts of jujube seed, 90-100 parts of platycladus seed, 150-160 parts of jujube, 160-170 parts of fried licorice, 160-170 parts of astragalus, 150-160 parts of angelica, 150-160 parts of salvia miltiorrhiza, and 155-165 parts of schisandra chinensis. The raw medicinal materials in the traditional Chinese medicine composition are based on the polygala root, and are combined with the jujube seed, the platycladus seed, the jujube, the fried licorice, the astragalus, the angelica, the salvia miltiorrhiza and the schisandra chinensis. The components have a synergistic effect, can treat insomnia, anxiety depression and AD, and have the advantages of small side effect of traditional Chinese medicine and difficulty in drug resistance.

The invention relates to the technical field of traditional Chinese medicine compositions and cosmetics, and discloses an anti-aging traditional Chinese medicine compound composition which is prepared from cistanche, radix achyranthis bidentatae, eucommia ulmoides, dendrobium flowers, polygala tenuifolia, roses, Chinese yam, angelica sinensis, salvia miltiorrhiza and liquorice. The traditional Chinese medicine compound composition prepared by the method can significantly inhibit the activity of an intracellular senescence marker beta-galactosidase and the expression of P16 or P21, improve the oxidation resistance of cells, improve the spatial learning and memory ability of senescent mice and recover the cardiac ejection ability of mice, exert a significant anti-senescence effect, and has good application prospects. The method has great popularization and application values.

The present application relates to a kind of pneumatic rolling ring cutting type shanzhai medicine core pulling machine. Mainly solve the technical problems of complex structure and high production cost of existing shanzhai core pulling machine. The technical scheme adopted by the present application is: a kind of pneumatic rolling ring cutting type shanzhai medicine core pulling machine, it includes mobile workstation, mobile slide rail, core pulling mechanism, pneumatic ring cutter mechanism and pneumatic rotary jaw mechanism, the pneumatic rotary jaw mechanism is installed in the left side of the workstation of mobile workstation setting, the pneumatic ring cutter mechanism is set on the workstation of mobile workstation setting and located in the front end of the clamping block of pneumatic rotary jaw mechanism setting, the mobile slide rail is installed on the workstation of mobile workstation setting and located in the right side of pneumatic ring cutter mechanism, the core pulling mechanism is connected with mobile slide rail by the mobile core pulling platform of setting and can move on mobile slide rail. The present application has the advantages of high working efficiency, good quality of shanzhai barrel and low cost.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a qi-tonifying and beautifying pill and a preparation method thereof. The qi-tonifying and beautifying pill is prepared from the following main raw materials in parts by weight: 360g of chrysanthemum morifolium ramat, 26g of Changbai mountain ginseng slices, 52g of bighead atractylodes rhizome, 72g of astragalus membranaceus, 72g of mulberry, 120g of prepared rehmannia root, 22g of dried rehmannia root, 52g of poria cocos, 120g of angelica sinensis, 28g of processed polygala tenuifolia, 120g of salted morinda officinalis, 120g of fructus lycii, 22g of pepper, 28g of Chinese yam, 28g of poria with hostwood, 60g of salted semen cuscutae, 60g of eucommia ulmoides and 60g of rhizoma polygonati. According to the qi-tonifying and beauty-maintaining pill and the preparation method thereof, the qi-tonifying and beauty-maintaining pill is scientific in formula and strong in synergistic effect, and can achieve the effects of tonifying qi and blood and regulating internal organs together, so that the remarkable effects of tonifying qi and maintaining beauty are achieved; meanwhile, the preparation method is standard and efficient, the retention rate of active ingredients of the raw materials and the pill stability can be improved, the taste is improved, and the pill is convenient to take.

The invention provides a traditional Chinese medicine sleeping pillow which comprises a traditional Chinese medicine pillow inner, and the traditional Chinese medicine pillow inner comprises a pillow inner sleeve and a traditional Chinese medicine particle filling layer arranged in the pillow inner sleeve; the traditional Chinese medicine particle filling layer comprises the following components in parts by weight: 80-100 parts of chrysanthemum, 50-70 parts of crude dragon bone, 10-20 parts of sandalwood, 50-70 parts of processed polygala tenuifolia pulp, 45-65 parts of junci medulla, 55-65 parts of albizia flower, 55-65 parts of raw dens draconis, 8-10 parts of borneol, 80-100 parts of clove, 85-90 parts of rhizoma acori graminei, 85-95 parts of vine of multiflower knotweed, 85-95 parts of calcined magnet, 50-70 parts of folium artemisiae argyi and 50-70 parts of pericarpium citri reticulatae. The detachable traditional Chinese medicine pillow inner and plastic neck support structure is adopted, pillow inner replacement and essential oil supplementation are facilitated, and maintenance is convenient and fast; ergonomic design improves use comfort and adapts to neck physiological curves of different crowds.

The application discloses a traditional Chinese medicine combined incense bead for soothing nerves and helping sleep, which is prepared from the following raw materials in a mass ratio: 5g of agarwood, 5g of sandalwood, 3g of Chinese flowering crabapple, 4g of fried Chinese date seed, 2g of polygala, 2g of lavender, 1g of natural borneol camphor and 16g of cypress stick powder. The application adds fried Chinese date seed to the traditional liver-soothing incense material to supplement the heart-nourishing and liver-nourishing effect, adds polygala to communicate the heart and kidney, and adds lavender to soothe nerves, so that three types of insomnia core pathogenesis, i.e., liver stagnation, heart blood deficiency and heart-kidney disharmony, can be solved at the same time. The single formula covers multiple types of insomnia, and the nerve-soothing effect is much better than that of the single formula. The natural borneol camphor is added as a meridian-inducing transdermal absorption carrier in the combined incense bead formula, so that the technical defect that the effective components of the traditional incense bead only float on the body surface and have weak effect is solved.

The invention relates to the technical field of traditional Chinese medicine, and provides a medicine for treating radiotherapy-induced leucopenia and a preparation method and application thereof.The medicine comprises a traditional Chinese medicine composition, and the traditional Chinese medicine composition comprises ginseng, rhizoma atractylodis macrocephalae fried with bran, poria cocos, Chinese yam, pericarpium citri reticulatae, radix aucklandiae, fructus amomi, radix astragali preparata, angelica sinensis, fried semen ziziphi spinosae and processed polygala tenuifolia. When the traditional Chinese medicine composition acts on mammals, it is verified that the traditional Chinese medicine composition has a good curative effect on leucopenia and / or bone marrow hematopoietic tissue area reduction caused by radiotherapy, and the level of pro-inflammatory cytokines increased due to radiotherapy in serum of the mammals is lowered.

The invention provides a nerve-soothing and sleep-aiding compound for improving sleep quality and application of the nerve-soothing and sleep-aiding compound. The nerve soothing and sleep aiding compound for improving sleep quality comprises the following components in parts by weight: 10-30 parts of a spina date seed extract, 5-15 parts of a polygala tenuifolia extract, 2-5 parts of sandalwood, 2-3 parts of bergamot, 2-3 parts of corydalis tuber, 1-2 parts of albizia flower, 1-2 parts of chamomile, 2-3 parts of lavender, 3-5 parts of sweet orange and 8-20 parts of a poria cocos extract. According to the nerve-soothing and sleep-aiding compound for improving the sleep quality and the application thereof, the nerve-soothing and sleep-aiding compound adopts various natural plant extracts and functional components, is safe and free of side effects, does not generate drug dependence and drug resistance after being used for a long time, is suitable for being used by people with various sleep disorders, and is free of toxic and side effects. According to the compound, through the synergistic effect of various components, the sleep time can be remarkably shortened, the sleep time can be prolonged, the sleep depth can be improved, the sleep quality can be effectively improved, and the compound has a good improvement effect on sleep disorders caused by pressure, anxiety and the like.

The invention relates to the technical field of preparation and application of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating Alzheimer's disease and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 3-9 parts of ginseng, 3-10 parts of morinda officinalis, 6-12 parts of dogwood, 3-10 parts of rhizoma acori graminei, 3-10 parts of polygala tenuifolia, 3-6 parts of rhodiola rosea, 3-6 parts of China rose, 2-3 parts of hypericum perforatum, 3-6 parts of saussurea involucrate, 9-15 parts of cortex lycii radicis, 3-12 parts of golden cypress and 1-5 parts of agilawood. The traditional Chinese medicine composition provided by the invention accords with the traditional Chinese medicine treatment concept of tonifying deficiency and filling marrow, inducing resuscitation and soothing nerves, dredging collaterals and eliminating evil, and tonifying spleen and assisting transportation, not only can relieve damage of neurons, but also can reverse alzheimer disease related disorder signal channels in neuronal cells, microglial cells and astrocytes.

The invention discloses a traditional Chinese medicine composition for preventing and treating climacteric insomnia. The traditional Chinese medicine composition is mainly prepared from cortex moutan, mantis egg-case, poria cocos, rhizoma anemarrhenae, pericarpium citri reticulatae, folium apocyni veneti, cortex albiziae, polygala tenuifolia, roses, herba lycopi, pericarpium arecae, fructus liquidambaris and the like according to a certain weight ratio. The traditional Chinese medicine can be prepared into any common oral dosage form. The whole formula has the effects of nourishing blood and soothing liver, activating blood and removing stasis, promoting qi circulation and inducing diuresis, and nourishing yin and clearing heat, and has an exact curative effect on preventing and treating climacteric insomnia.

The application discloses a traditional Chinese medicine composition for treating ventricular premature beat and a preparation method thereof. The composition comprises the following raw materials: radix pseudostellariae, schisandra chinensis, rhizoma corydalis, radix notopterygii, polygala, lotus plumule, albizia julibrissin, calcined semen orystalis, gancao, radix scabiosae, and herba artemisiae annuae. The traditional Chinese medicine composition is suitable for patients with ventricular premature beat. The composition can be prepared into any common oral dosage form and health product, has the effects of benefiting qi and nourishing yin, regulating qi and activating blood, calming the nerves and stabilizing palpitation, can effectively improve the symptoms of the patients, and can significantly reduce the number of premature beats, and is especially suitable for the application to ventricular premature beat of qi-yin deficiency and blood stasis.

The application belongs to the technical field of medicine, and particularly relates to a traditional Chinese medicine composition for treating cognitive impairment and a preparation method thereof. The preparation method of the traditional Chinese medicine composition comprises the following steps: S1. adding modified mesoporous silicon dioxide to water extracts of ginseng, poria cocos, polygala, acorus gramineus, bupleurum, radix curcumae, cyperus rotundus and chuanxiong, grinding, vacuum drying, and preparing an intermediate product; and S2. mixing the intermediate product with microcrystalline cellulose, mannitol, sodium carboxymethyl starch and a stabilizer, adding a binder, extruding and rounding, drying, sieving, and preparing the traditional Chinese medicine composition. The method is simple in steps and easy to put into production. The obtained traditional Chinese medicine composition can significantly improve the oxidative stress damage of a vascular dementia model rat.

The invention belongs to the technical field of health-care tea drinks, is homologous in medicine and food, and is prepared into agilawood tea pills with health-care functions by taking agilawood in a court secret prescription and various traditional Chinese medicinal materials as a formula and taking Chinese tea as a raw material in combination with a Chinese traditional pill preparation process. The tea pills have the health-care effects of enriching yin and nourishing kidney; according to the preparation method and the formula, the traditional Chinese medicine comprises various natural traditional Chinese medicinal materials such as freshwater sponge, lamp grass carbon, fructus cnidii, semen plantaginis, cistanche deserticola, semen cuscutae, malan flower, morinda officinalis, herba epimedii, piper cubeba, anise, fructus rosae laevigatae, fructus psoraleae, radix aucklandiae, fructus caryophylli, semen allii tuberosi, monkshood, polygala tenuifolia, rhizoma zingiberis, agilawood, rhizoma alismatis, semen juglandis, semen boitae, mantis egg-case, fructus lycii, pulp of dogwood fruit, poria cocos and radix rehmanniae preparata. The traditional Chinese medicine has the effects of nourishing yin and strengthening, warming and tonifying kidney qi, strengthening muscles and bones, coordinating intestines and stomach, improving dysmenorrhea, refreshing and restoring consciousness, and strengthening heart and lung.

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by mass: 6-15 parts of codonopsis pilosula, 15-30 parts of astragalus membranaceus, 10-15 parts of bighead atractylodes rhizome, 10-15 parts of poria cocos, 6-10 parts of honey-fried licorice root, 10-15 parts of angelica sinensis, 10-15 parts of prepared rehmannia root, 10-12 parts of radix paeoniae alba, 6-10 parts of ligusticum wallichii, 3-6 parts of cassia twig, 6-10 parts of schisandra chinensis, 6-10 parts of polygala tenuifolia, 12-15 parts of endothelium corneum gigeriae galli, 6-10 parts of pericarpium citri reticulatae, 5-10 parts of fresh ginger and 10-15 parts of jujube. And the body function and psychological state of the patient are improved through multi-target regulation.

The invention belongs to the technical field of traditional Chinese medicine preparations, and discloses a retroauricular administration type sleep-promoting traditional Chinese medicine compound composition and a preparation method thereof. The retroauricular administration type sleep-promoting traditional Chinese medicine compound composition is prepared from pericarpium citri reticulatae, fingered citron, agastache rugosus, liquorice, lily, fried spina date seed, processed polygala tenuifolia, schisandra chinensis, poria with hostwood, platycladi seed, acanthopanax, cortex albiziae, rhizoma acori graminei, rhizoma anemarrhenae, albizia flower and pseudo-ginseng according to a specific mass ratio. According to the preparation method disclosed by the invention, the dissolution rate and the transdermal absorption efficiency of active ingredients in the medicinal materials are remarkably improved by carrying out cell wall breaking pretreatment on the prepared polygala tenuifolia and / or the schisandra chinensis, including modes of enzymolysis, bacterium-enzyme synergistic fermentation and plasma-assisted wall breaking. According to the preparation method, an ethanol-water mixed solution is used for extraction and centrifugal separation, and a medicine extracting solution is obtained. The composition can quickly and efficiently play a role in promoting sleep in a retroauricular administration manner, and has the comprehensive effects of soothing the nerves, stabilizing the mind, soothing the liver, relieving depression and promoting the circulation of heart and kidney.

The present application relates to a composition with improved sleep quality function and its preparation method, belonging to the technical field of cosmetics and external preparation. The composition comprises: gamma-aminobutyric acid, isosorbide dimethyl ether, plant extract compound (pink passion fruit, jujube kernel, polygala, rehmannia), aromatic essential oil (lavender oil, dalbergia odorifera oil, linaloe extract), menthol, polyacryl dimethyl ammonium taurate and moisturizing and preservative system. By using isosorbide dimethyl ether and gamma-aminobutyric acid to form a penetration precursor solution, the problem of transdermal difficulty of gamma-aminobutyric acid is solved; and through a specific preparation process, a gradient sleep-aiding release based on the volatility difference of essential oil and gel wrapping is constructed, realizing the phased sleep-aiding effect of instant cooling to block irritability, induction of relaxation synergistic effect, and whole night slow release to maintain deep sleep. The composition has high transdermal absorption rate, controllable aroma release timing, long-lasting sleep-aiding effect, and good application prospect.

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating diabetes-related erectile dysfunction as well as a preparation method and application of the traditional Chinese medicine composition. The composition consists of a pharmaceutically acceptable carrier and an active ingredient, wherein the active ingredient consists of the following components in parts by weight: 5-15 parts of rhizoma acori graminei; 5-15 parts by weight of ligusticum wallichii; 5-15 parts by weight of radix curcumae; 5-15 parts by weight of polygala tenuifolia; 5-15 parts by weight of Chinese herbaceous peony; 5-15 parts by weight of Chinese angelica; 10-20 parts by weight of Radix Astragali; 5-15 parts by weight of semen cuscutae; 5-15 parts by weight of herba epimedii; 5-15 parts by weight of dens draconis; 5-15 parts by weight of tribulus terrestris; 5-15 parts by weight of radix bupleuri; and 5-15 parts by weight of rhizoma cyperi. The composition is prepared into various oral preparations such as granules, tablets, capsules, pills and the like through the processes of extraction, concentration, drying, granulation and the like. The application can significantly improve the erectile function index, erectile hardness and sexual life quality of DMED patients, improve the serum testosterone level of the patients and reduce blood sugar, and has the advantages of few adverse reactions and good safety.