187 results about "Xanthone" patented technology

Metabolic energy capacity enhancing compositions and methods for reducing oxidative stress and improving vitality in a mammal are disclosed. A composition for increasing metabolic energy capacity may be in a palatable liquid formulation or a solid dosage form and typically includes an anti-oxidant containing phytonectar and an energy catalyst. An anti-oxidant may include a polyphenol, anthrocyanin, bioflavonoid, proanthocyanidin, and a xanthone. An energy catalyst may include a mineral, vitamin, co-vitamin, carbohydrate and a lipid. In a presently preferred embodiment a composition includes phytonectar extracts from grape, aloe vera, apple, morinda citrifolia, scullcap, blueberry, prune, cranberry, elderberry, bilberry, and gentain and a mineral blend containing calcium, magnesium, manganese, zinc, chromium, selenium, iron, copper, molybdenum, vanadium, potassium, iodine, and cobalt. A method for increasing metabolic energy capacity in a mammal may include consuming a chemical component having the ability to undergo oxidation, producing free radicals and administering a composition having an anti-oxidant containing phytonectar and an energy catalyst.

The present invention relates to pharmaceutical, therapeutic, nutritional, cosmetic, and dermatological compositions derived from the preicarp (rind) of the Garcinia mangostana L plant and the novel extraction processes used to produce those compositions. Specifically, the present invention relates, in part, to an approximately 0.01% to about 80% mixture of a xanthone-rich mangosteen pericarp (rind) extract in novel combinations for pharmaceutical, cosmetic, therapeutic or dermatological compositions that yield surprising health benefits. Additionally, the present invention relates, in part, to novel extraction processes that result in the production of the novel compositions of the invention.

Nutritional supplement drink compositions containing extracted xanthones, flavoring agents, aqueous carriers, and one or more vitamins, minerals, carotenoids, flavonoids, or other nutrients are described. The xanthones are extracted from xanthone-rich plants, such as the mangosteen tree, Brazilian malva-do-santo, and a Chinese herb, Swertia davidi.

The present invention relates to pharmaceutical, therapeutic, nutritional, cosmetic, and dermatological compositions derived from the preicarp (rind) of the Garcinia mangostana L plant and the novel extraction processes used to produce those compositions. Specifically, the present invention relates, in part, to an approximately 0.01% to about 80% mixture of a xanthone-rich mangosteen pericarp (rind) extract in novel combinations for pharmaceutical, cosmetic, therapeutic or dermatological compositions that yield surprising health benefits. Additionally, the present invention relates, in part, to novel extraction processes that result in the production of the novel compositions of the invention.

The invention discloses an azaxanthone compound and applications of the azaxanthone compound in organic electroluminescent devices. According to the present invention, the azaxanthone compound uses azaxanthone as the core, the molecules are not easily crystallized and are not easily aggregated, and the azaxanthone compound has good film forming property; and with the application of the azaxanthone compound as the light emitting layer main material of the OLED light emitting device, the current efficiency, the power efficiency and the external quantum efficiency of the device are greatly improved, and the service life of the device can be remarkably improved.

The invention discloses a compound based on xanthone and application thereof. The compound uses xanthone as a parent nucleus, which is connected to a heteroaromatic group, so as to destroy the molecular symmetry, and thus further destroy the crystallinity of molecules and avoid the aggregation between molecules. The compound based on xanthone has good film-forming property, and can be applied to organic light emitting diode as a luminescent layer; and the OLED device using the compound based on xanthone has good photoelectric property, and can meet the requirements of panel manufacturing enterprises.

This invention relates to novel xanthone compounds, their preparation and use as medicament. More particularly this invention is directed to the isolation of the novel xanthone natural product sootepenseone from Dasymaschalon sootepense Craib, Annonaceae, its identification and derivatization, and the use of sootepenseone and its derivatives as anticancer agents.

The invention discloses a mangosteen total xanthone extract and a preparation method thereof and well as application in the preparation of a TR3 receptor inducer, belonging to the field of pharmaceuticals and foods. The mangosteen total xanthone extract is applied to preparing foods or medicines for preventing or treating cancers, hepatitis or atherosclerosis as the TR3 receptor inducer. The TR3 receptor inducer and pharmaceutically-acceptable vectors are mixed to prepare powders, tablets, capsules, pills, suppositories, dropping pills, enteric-coated agents, injections, syrups, emulsions, suspensions, tinctures, ointments or sprays. Based on a mechanism that TR3 is possible to be an ideal molecular target for screening anti-tumor and cardiovascular medicines, the invention discovers and develops compounds for selectively controlling the TR3 expression approach or medicine compositions with the advanced treating characteristic and has practical meaning.

The invention discloses an organic light emission diode device containing a xanthone compound and an application thereof. The device comprises a hole transport layer, a light emission layer and an electron transport layer. The material of the light emission layer of the device comprises a compound with xanthone as a core group, and the structural formula of the compound is shown in the general formula (1). According to the material with xanthone as the core group, due to a small triplet and singlet energy difference, energy transfer between host and guest materials can be realized easily, energy that is originally lost in a heat form is easily available, and the high efficiency of the device can be acquired more easily. Further, when a fluorescent material is selected as a doped material, light emission radiation of the doped material is acquired more easily, and a long service life of the material can be acquired more easily.

The present invention relates to the field of medical technology, and in particular relates to a category of novel sulphonyl substituted xanthene ketone compounds that have a structural formula as shown in the right, a preparation method and application thereof. The compound has high inhibitory activity for ACAT1 / ACAT2; most of the compounds have high inhibitory activity for acyl coenzyme A cholesterol acyltransferase (ACAT). The compounds can be used for preparing anti-atherosclerosis drug combination. Furthermore, the compounds can be used as a preventive or a treating agent of such diseases as angina, myocardial infarction, cerebral infarction, apoplexy, Alzheimer's disease, acute coronary syndrome, PTCA or restenosis of coronary artery after a bracket is arranged. The compounds can be used as a treating agent to adjust the function of sebaceous glands of the skin and inhibit the excessive generation of sebum. And the compounds can be used for treating such diseases as acne-like damage caused by oily skin, acne, seborrhea and corticosteroids.

The invention belongs to the field of chemical synthesis, in particular relates to a synthesis method of a natural product mangostin which is shown in the formula (I) and has good anti-tumor activity, anti-inflammation activity and anti-bacterial activity. The method provided by the invention comprises the following steps of: taking 2,4,5-trialkoxy benzoic acid and 1,3,5-trialkoxy benzene as initial raw materials; carrying out acyl chlorination, Friedel-Crafts acylation and cyclization to prepare a key intermediate 1,3,6,7-tetraalkoxy xanthone; and then, carrying out dealkylation, allylation, Claisen rearrangement, methylation, oxidation reaction, WITTING reaction and dealkylation reaction so as to prepare the mangostin.

The invention provides a Tibetan capillaris extract, which comprises components of secoiridoid, xanthone, triterpene and the like, wherein the total content of the three components is 20%-80% (by weight). The invention also provides a preparation method of the Tibetan capillaris extract, and a pharmaceutical composition containing the Tibetan capillaris extract. The Tibetan capillaris extract hasthe obvious function of benefiting the cholecyst, and has obvious functions of protecting and improving acute liver injury caused by chemicals and hypohepatia of obstructive jaundice.

A nutritional supplement composition containing extracted xanthones, vitamins, minerals, carotenoids, flavonoids, and other nutrients is described. The xanthones are extracted from xanthone-rich plants, such as the mangosteen tree, Brazilian malva-do-santo, and a Chinese herb, Swertia davidi.

Three pairs of C-2 epimeric xanthones isolated from Garcinia hanburyi and method for efficiently separating the xanthone compounds into individual epimers, each of which possesses varying biological effects. The compounds are useful for their anticancer effects, particularly because they are shown to be non-substrates of the multidrug-resistance transporter. Some of the epimers have significant inhibitory effects on cytochrome P450 systems. The xanthone compounds of the present invention are gambogic acid, epigambogic acid, isogambogic acid, isoepigambogic acid, 30-hydroxygambogic acid and 30-hydroxyepigambogic acid.

The invention relates to xanthone compounds separated from a fermentation product of a Paraconiothyrium sp.YM311593, and applications thereof, belonging to the technical field of microbial medicines. The produced strain YM311593 is collected in the CCTCC (China Center For Type Culture Collection) on April 10th, 2013, with the CCTCC No:M2013142. The xanthones compounds can be obtained by carrying out conventional fermentation and extraction separation on the strain YM311593. Activity tests proved that the compounds have obvious anti-tumor cell activity and anti-plant pathogenic fungi activity, and has a potential application in preparation of a new anti-tumor medicine and a new agricultural antibacterial agent.

The invention relates to a fluorescence detection method and provides a fluorescent probe which has high sensitivity and high selectivity and is used for detecting intracellular hypochloric acid and an application of thiospirolactone in intracellular hypochloric acid detection. The structure of the fluorescent probe for detecting the intracellular hypochloric acid is a triphenylmethane fluorescent probe with a Xanthone ring parent structure; and the fluorescent probes of the thiospirolactone all adopt corresponding spirolactones as raw materials. The thiospirolactone has high-sensitivity fluorescent response characteristics on hypochloric acid, and when being used in the fluorescent probe for detecting the intracellular hypochloric acid, the selectivity is high. The probe has strong lightstability, no illumination self oxidation, rapid response to an aimed compound, good cell permeability and no strong cytotoxicity, and a product formed by combining the fluorescent probe and the aimed compound has strong photobleaching resistance. The thiospirolactone used for detecting the hypochloric acid of the aimed compound has high sensitivity and strong specificity and other active oxygen in cells has no interference on the detection.

The invention discloses an active xanthone compound, which has a structure represented by a general formula (I) as follows. 2,4-dihydroxyl xanthones differing in concentration represent different degrees of antibacterial effects on staphylococcus aureus, therefore the active xanthone compound has a remarkable inhibiting effect.

The present invention relates to a UV irradiation assisted method of surface modification, which comprises: introducing a functional group L onto the surface of a polymer material P through the photochemical reaction of a photosensitive group X under UV irradiation, wherein the photosensitive group X comprises at least one xanthone unit.

Aromatic ketones having an extended fluoro-alkyl or fluoro-alkoxy moiety are disclosed. In particular aspects, the compounds comprise substituted 9-acridone, 9-xanthone, 4(1H)-quinolone, 4(1H) pyridone, 1,4-naphthoquinone, 9,10-anthraquinone derivatives. These preparations possess potent pharmacological activity for inhibiting malaria and mosquito-borne (Plasmodium) diseases. The haloalkyl / alkoxy aromatic compounds possess significant pharmacological activity, with IC50 values in the nanomolar and sub-nanomolar range, and reduced toxicity against host derived cells and tissues. Methods of using the fluoro-alkyl / alkoxy aromatic compounds in the treatment of malaria and other human and animal diseases are also disclosed. Agricultural uses of the fluoro-alkyl / alkoxy aromatic compounds, such as in control of fungal diseases and in the production of important commercial crops (apples, etc.), are also presented.

The invention discloses a heterocyclic compound with xanthone as a core and a preparation method and applications thereof, and belongs to the technical field of semiconductors. The structure of the compound provided by the invention is represented by a general formula (I) shown in the description. The invention also discloses the preparation method and the applications of the compound. The compound of the invention has high glass transition temperature and molecular thermal stability and has a suitable HOMO and LUMO energy leves, has a singlet-triplet energy level difference ([delta]Est), andcan be used as a doping material of a light emitting layer of an organic electroluminescent device, thereby improving the luminous efficiency and service life of the device.

The invention relates to an establishing method of rhizoma anemarrhenae HPLC-ELSD (High Performance Liquid Chromatography-Evaporative Light Scattering Detector) fingerprint and a standard fingerprint established by using the establishing method. The establishing method comprises chromatographic conditions, the preparation of a test substance solution, and the preparation of a control substance solution, wherein the chromatographic condition is a Thermo C8 chromatographic column (4.6mm*250mm, 5 microns); a mobile phase is an acetonitrile-0.2% acetic acid aqueous solution for gradient elution; the column temperature is 20 DEG C; the flow speed is 1mL.min<-1>; the flow speed of an ELSD atomizer is 2.6L.min<-1>; the temperature of a drift tube is 100 DEG C; and the sampling size is 20 microlitres. The establishing method provided by the invention has the advantages of good stability and repeatability, high precision, capability of simultaneous reflection of the characteristics of saponins and xanthones, which are the main chemical ingredients of the rhizoma anemarrhenae, and capability of reflecting the quality of the rhizoma anemarrhenae according to the overall characteristics of the chromatogram; and the establishing method can be used as one method for controlling the quality of the rhizoma anemarrhenae.

Skin care compositions containing xanthones extracted from plants are described. These compositions include lotions, creams, ointments, and the like that reduce wrinkles, give skin a more youthful appearance, provide antioxidant effects, protect the skin, and moisturize the skin. The compositions contain an admixture of a base and a xanthone-containing plant extract.

The present invention belongs to the field of Chinese medicine technology, and is especially isopentenyl ketone compound from cudrania and its application in preparing antitumor medicine. The isopentenyl ketone compound of the present invention has relatively high antitumor activity and function of inhibiting vascularization and may be used in preparing antitumor medicine.

The invention relates to a polymer surface modification method by ultraviolet irradiation. The polymer surface modification method by ultraviolet irradiation includes allowing a photosensitive group X to chemically react under ultraviolet irradiation so as to introduce a functional group L into the surface of polymer material P, wherein the photosensitive group X contains at least one xanthone unit.

The invention provides a medicinal compound for improving the immunity of a human body as well as a preparation method and application of the medicinal compound. The medicinal compound comprises the following components: algae-selenium polysaccharide, cordycepin, cordyceps polysaccharide, ganoderan, lycium barbarum polysaccharide, lentinan, codonopsis pilosula polysaccharide, resveratrol, a lily extract, a date extract and xanthone. The medicinal compound has the functions of improving cell function activity, rapidly improving the immunity of the human body, protecting and repairing cells, promoting marrow to generate thrombocyte, hematokrit and leukocyte, cancer cell diffusion can be effectively inhibited, the cancer cell activity can be degraded, and malignant tumor recurrence and metastasis can be effectively inhibited. According to the preparation method of the medicinal compound, the medicinal compound is prepared into an oral liquid which is convenient for patients to use and is convenient to carry about.

The invention relates to the field of natural compounds, especially to two novel compounds extracted from the bark of Garcinia oligantha and having a structural formula as described in the specification, or a pharmaceutically acceptable salt, hydrate or prodrug thereof, and a preparation method, a pharmaceutical composition and application thereof. In the formula, R is a methyl group or -CH2CH2CH=C(CH3)2. The compound can be used for preparation of drugs used for preventing and treating a plurality of tumors like prostatic cancers, liver cancers, lung cancers and colorectal cancers.

The invention discloses application of high mangiferin and aglycon thereof in preparation of a medicament for preventing and treating hyperuricemia and in particular relates to application of high mangiferin and aglycon thereof in preparation of a medicament for preventing and treating hyperuricemia as well as gout and lithangiuria brought by the hyperuricemia, and a medicine application way. The high mangiferin and aglycon thereof provided by the invention can be used for obviously reducing the concentration of serum uric acid in an animal for experiment and have the serum uric acid inhibition effect similar to that of a xanthine oxidase inhibition medicament allopurinol; and simultaneously, the high mangiferin and aglycon thereof provided by the invention can be used for obviously improving the concentration of uric acid in urine and have the uric acid excretion promoting function similar to that of a uric acid excretion promoting medicament probenecid. The high mangiferin and aglycon thereof provided by the invention are efficient, low in toxicity and high in safety, thus the high mangiferin and aglycon thereof are wide in application prospect.

The invention, relating to the field of pharmaceutical chemistry, particularly relates to a method for preparing 1,3,6,7-tetrahydroxy xanthone. According to the invention, 1,3,6,7-tetrahydroxy xanthone can be synthesized through two steps, the synthesis route is short, the steps are few, the operation is simple and easy to control, the prepared 1,3,6,7-tetrahydroxy xanthone has high purity and can be widely applied in industrial production.