260 results about "Proanthocyanidin" patented technology

The invention provides a technical method for improving the anti-aging effect of eurotium cristatum tea compound fermentation liquor, and belongs to the technical field of microorganisms, the Latin name of eurotium cristatum is Eurotium cristatum, the eurotium cristatum is preserved in the China Center for Type Culture Collection, and the preservation number is CCTCC M 2024643. According to the method, the yeast seed solution is inoculated into the tea-sea buckthorn leaf culture solution fermented by the eurotium cristatum, so that the content of anti-aging active components such as procyanidine B2, quercitrin, cyanidin-3-glucoside, nicotinic acid, naringenin and rutin in the fermentation culture solution can be remarkably increased through co-fermentation, and the elastase inhibition rate can be remarkably increased; the anti-aging effect of a component system of the fermentation culture solution is enhanced. The prepared tea-hippophae rhamnoides leaf compound fermentation liquor is suitable for development of anti-aging cosmetics and has a wide market prospect.

The invention relates to the technical field of high-barrier environment-friendly packaging films, and discloses a high-barrier environment-friendly packaging film with an antibacterial function, the high-barrier environment-friendly packaging film comprises a base layer, a nano composite barrier layer, a bio-based functional layer and an outer protective layer from bottom to top in sequence, and the layers are tightly attached through a coated starch-based adhesive. According to the high-barrier environment-friendly packaging film with the antibacterial function, good biodegradability of polyhydroxyalkanoate adopted in the base layer film, polycaprolactone which is adopted in the nano-composite barrier layer film and has a biodegradable function and konjac glucomannan in the biological functional layer film are utilized; the composite packaging film can be decomposed into carbon dioxide and water by microorganisms in various environments, has excellent flexibility and processability, can adapt to different packaging requirements, provides basic flexibility, structural support and green and environment-friendly effects for the whole packaging film, and has a wide application prospect. The procyanidine arranged in the outer protective layer film provides stronger antibacterial property and water solubility for the whole packaging film.

The invention relates to application of procyanidine in preparation of a medicine for inhibiting and killing in-vitro parasitic ciliates of fishes, and belongs to the technical field of medicines for fish parasitic diseases. The procyanidine is applied to preparation of drugs for inhibiting and killing in-vitro parasitic ciliates of fishes. The procyanidine is applied to preparation of the medicine for inhibiting and killing the in-vitro parasitic ciliates of the marine fishes for the first time, especially for inhibiting and killing cryptocaryon irritans, the in-vitro parasites can be completely inhibited and killed within an effective dosage range, and the effect of preventing and treating the ichthyophthiriasis of the marine fishes is achieved. The procyanidine serving as a main medicine component is wide in source, has an industrial preparation process, is low in price, has a huge potential of being developed into a novel fish medicine for preventing and treating in-vitro parasitic ciliates of fishes, and is wide in application prospect. The procyanidine has small toxic and side effects, is easy to degrade and eliminate, can effectively avoid negative effects such as environmental pollution and drug residues, and promotes sustainable, green and healthy development of the aquaculture industry.

The invention provides a ginseng exosome anti-aging and anti-oxidation composition and a preparation method thereof, and relates to the field of nursing materials, the ginseng exosome anti-aging and anti-oxidation composition comprises Exo nano-vesicles, procyanidine and cationic liposome, the Exo nano-vesicles are derived from ginseng extracellular fluid, the procyanidine is derived from the cationic liposome, and the cationic liposome is derived from the procyanidine. The ginseng exosome anti-aging and anti-oxidation composition provided by the invention can effectively improve skin wrinkles, enhance skin elasticity, promote collagen synthesis, inhibit collagen degradation and inhibit elastin degradation through the combined action of the Exo nano-vesicles, Pro and cationic lipidosome; degradation of elastin can cause skin to lose resilience, formation of wrinkles is accelerated, and facial skin can be effectively improved and wrinkles can be reduced by promoting synthesis of collagen and inhibiting degradation of elastin.

The invention discloses a mint McTTG2 gene as well as an expression protein and application thereof, and relates to the technical field of plant genetic engineering. The nucleotide sequence of the mint McTTG2 gene disclosed by the invention is shown as SEQ ID NO. 1, and the amino acid sequence of the expression protein of the mint McTTG2 gene is shown as SEQ ID NO. 2. The method comprises the following steps: constructing an expression vector of a mint McTTG2 gene, and transforming the expression vector into an arabidopsis thaliana mutant; and cultivating and screening to obtain a transgenic arabidopsis thaliana plant of which the procyanidine content is obviously increased. A transgenic experiment shows that after the McTTG2 gene is over-expressed in the mutant ttg2-7, the content of procyanidine is remarkably increased; compared with the mutant ttg2-7, the number of epidermal hairs on leaves of ttg2-7 / 35S:: McTTG2-1 and-2 strains is obviously increased, which is close to that of wild strains. Gene resources are provided for plant variety improvement, and cultivation of new mint varieties is facilitated.

The invention relates to the field of cosmetics, in particular to a berry composition for scalp care and a preparation method and application thereof, and the preparation method comprises the following steps: A, pretreating fruits to obtain berry freeze-dried powder; b, preparing a deep eutectic solvent; c, mixing the berry freeze-dried powder with the deep-eutectic solvent, and performing oscillation extraction to obtain a berry procyanidine crude extract; d, purifying the berry procyanidine crude extract with macroporous resin to obtain a first purified berry procyanidine product; e, removing the solvent from the first purified berry proanthocyanidins to obtain a second purified berry proanthocyanidins; and F, dissolving epicatechin, mixing the dissolved epicatechin with the second purified product of the berry procyanidine, uniformly heating in a vacuum environment, cooling after relieving the vacuum environment, mixing with amino acid hydrochloride, and preserving heat to obtain the berry extract.

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.

The invention relates to the field of aquatic feed, and provides a low-temperature adhesive type aquatic feed particle composition and a preparation method thereof. The composition is composed of puffed soybean meal, flour, fish meal, low-temperature directed enzyme, microcrystalline cellulose, modified zein nanoparticles, a protein adhesive and a modified zein ethanol water solution. The preparation method comprises the following specific steps: reacting soybean protein isolate with cross-linking enzyme to generate a protein adhesive, reacting proanthocyanidins with gallic acid to generate gallic acylated proanthocyanidins, and carrying out multi-step treatment on zein. Experimental results show that the composition has excellent water resistance and oxidation resistance, and the growth efficiency and the survival rate of aquatic animals are remarkably improved. The preparation method is simple, the cost is low, heat-sensitive substances in the feed are not damaged, and an economical, efficient and nutrient-rich feed solution is provided for aquaculture.

The invention relates to the technical field of insulin resistance reversal, in particular to a composition with an insulin resistance reversal component and a preparation method thereof.The composition comprises quercetin, procyanidine, malic acid, magnesium carbonate, zinc lactate and cereals, fasting blood glucose, fasting insulin and an insulin resistance index can be reduced through synergistic interaction of all the components, and the insulin resistance index can be reduced; according to the traditional Chinese medicine composition, the insulin sensitivity index is improved, and the problems that in the prior art, traditional Chinese medicine compositions are complex in component, effective components capable of reversing insulin resistance and the synergistic mechanism are unclear, and the content of the effective components in the same medicine is inconsistent due to the influence of the growth environment, so that the treatment effect is unpredictable are solved.

The application belongs to the technical field of food processing, and particularly relates to an oat protein-pectin-proanthocyanidin compound and a preparation method thereof. The oat protein is mixed with water, and an alkali liquor is added to adjust the pH to obtain a protein material solution for medium grinding. Then, pectin is added to the ground protein material solution, and proanthocyanidin powder is added after the pH is adjusted, and secondary medium grinding is performed to obtain an oat protein-pectin-proanthocyanidin solution. Then, hydrochloric acid is slowly added to adjust the pH to 6.8-7.0. Finally, the protein solution is centrifuged, and the supernatant is spray dried to obtain the oat protein-pectin-proanthocyanidin compound. The oat protein-pectin-proanthocyanidin compound prepared by the method is a brand-new protein system, and solves the problems of poor dispersibility, nutritional defects and poor emulsifying property of oat protein, and has a wide application prospect.

The invention relates to the technical field of preparation of Pickering emulsion stabilizers, in particular to a protein-polyphenol-polysaccharide ternary covalent complex as well as a preparation method and application thereof. The method comprises the following steps: step 1, preparing a whey protein isolate aqueous solution, completely hydrating the whey protein isolate aqueous solution, compounding a grape seed oligomeric proanthocyanidins aqueous solution and a hydrated protein aqueous solution, adjusting the pH value, and carrying out stirring reaction and dialysis freeze-drying to prepare a protein-polyphenol binary compound; and 2, compounding the binary compound solution with the lycium barbarum polysaccharide solution, uniformly stirring, carrying out Maillard reaction to obtain a ternary compound solution, and freeze-drying to obtain the protein-polyphenol-polysaccharide ternary compound. The invention provides a non-toxic, harmless and pollution-free natural emulsifier and stabilizer, and simultaneously prepares a Chinese wolfberry seed oil Pickering emulsion capable of loading nutritional ingredients and active substances, thereby providing reference for screening research of the natural emulsifier and protection of nutritional ingredients of Chinese wolfberry seed oil, which are easy to photodecompose and oxidize; the problem that the effect of protein serving as a Pickering emulsion stabilizer in the prior art is poor is solved.

The invention discloses a preparation method of bread containing a ternary covalent compound. The preparation method comprises the following steps: preparing the following raw materials: 300 g of flour, 90-120 g of water, 4-6 g of yeast powder and 30-50 g of granulated sugar; the bread is prepared from, by weight, 1-3 g of salt, 1-2 eggs, 4-6 g of bread improver and 25-35 g of butter. 3 g to 6 g of a ternary covalent complex; the bread raw materials are mixed and kneaded into dough for primary fermentation, the dough is divided and put into a mold for secondary fermentation after primary fermentation, baking is conducted after secondary fermentation is completed, and finished bread is obtained after baking is completed. The protein-polysaccharide-polyphenol ternary complex is added into the bread, so that the oxidation resistance of the bread can be effectively improved, the digestion degree of procyanidine in the stomach is reduced, the absorption effect of intestinal tracts is improved, the bioavailability is improved, and meanwhile, the stability of the bread is also improved. The polyphenol is stable in the stomach, can be massively released in the intestinal tract after being digested in the intestinal tract, is favorable for maintaining the balance of beneficial bacteria and harmful bacteria in the intestinal tract, and promotes the health of the intestinal tract.

A trace element supplement consisting of lutein, zeaxanthin, astaxanthin, anthocyanins, and proanthocyanidins is designed to improve retinal health in children and adolescents, relieve eye strain, and slow the progression of myopia. The daily dose is 1–20 mg lutein, 0.2–4 mg zeaxanthin, 0.5–8 mg astaxanthin, 10–700 mg taurine, and 0.5–8.5 mg zinc; the nighttime dose is 1–100 mg eyebright extract, 10–300 mg chamomile extract, 1–200 mg anthocyanins, and 1–500 mg proanthocyanidins.

The invention relates to a preparation process of a novel Danfit sparkling grape juice, and belongs to the technical field of grape juice preparation. Fully mature, brightly colored, non-rotten and pesticide-free Danfit grape fruits are selected, rinsed in clean water, dried and then the fruit stems are removed; the grapes are crushed after being quickly frozen at low temperature, and the pulp after low-temperature immersion is squeezed using a press to make all the juice flow out; the squeezed juice is first filtered with a filter screen, then put into a sterilized container, a clarifier is added, and naturally clarified at low temperature; the upper clarified liquid is taken and finely filtered through a modified microfiltration membrane; the sugar-acid ratio of the grape juice is adjusted and then homogenized, and then rapidly cooled after ultra-high temperature instantaneous sterilization; the sterilized grape juice is cooled and added to a soda mixer, filled with carbon dioxide, and then poured into a sterilized glass bottle, and sealed and packaged; the novel Danfit sparkling grape juice prepared by the invention contains a high level of proanthocyanidins.

The invention provides procyanidine C1 nanoparticles as well as a preparation method and application thereof, and relates to the technical field of food processing. The nanoparticles are prepared by using lysine as a coupling agent, polysaccharide (such as polygonatum polysaccharide, dendrobium polysaccharide and lycium barbarum polysaccharide) as an embedding wall material and procyanidine C1 as a core material through a self-assembly method. The nanoparticles can significantly improve the embedding rate and stability of the proanthocyanidins C1, enhance the anti-oxidation and anti-aging effects of the proanthocyanidins C1, can be used for constructing a nano delivery system or preparing anti-aging and anti-oxidation medicines and foods, and have wide application prospects.

The invention provides weak acid wet toilet paper special for women and a preparation process thereof, and belongs to the technical field of wet toilet paper preparation. The preparation process comprises the following steps: preparing the plant source weak acidity adjusting compound; preparing a bacteriostatic microcapsule compound; and preparing the weakly acidic wet toilet paper. The weakly acidic wet toilet paper prepared by the invention can relieve redness and pruritus of private skin caused by friction and secretion stimulation and enhance the skin barrier function, and an'instant bacteriostasis-long-acting regulation 'dual path is formed by the bacteriostatic component released by the microcapsule, the cranberry proanthocyanidin and the lactic acid bacteria metabolite, so that the recurrence rate of vaginitis is reduced.

The invention discloses a peanut red skin procyanidine microcapsule as well as a preparation method and application thereof, and belongs to the technical field of microcapsules. The peanut red skin procyanidine microcapsule is prepared by the following method: adding peanut red skin procyanidine powder into a wall material solution, and uniformly mixing to obtain a mixed emulsion; and homogenizing the mixed emulsion, and freeze-drying to obtain the peanut red skin procyanidine microcapsule. The inulin and the whey protein are used as wall materials, the peanut red skin procyanidine is used as a core material, and the proportion of the inulin and the whey protein is optimized, so that the prepared microcapsule can weaken the influence of the peanut red skin procyanidine powder on the color and luster of food and improve the environmental stability and the gastrointestinal tract slow release characteristic of the microcapsule. And meanwhile, the prebiotic inulin is used as a wall material raw material, so that the intestinal microecology can be improved, and the intestinal health can be promoted.

The invention belongs to the field of health care products and biological medicines, and particularly discloses an anti-aging stem cell PQQ cordyceps sinensis ganoderma lucidum anthocyanin compound preparation and application thereof.The preparation is composed of apple stem cell extract, PQQ, cordyceps militaris extract, ganoderma lucidum extract, procyanidine and pharmaceutic adjuvants and can be made into capsules or pills or tablets. The preparation method comprises the following steps: extracting the raw material components, uniformly mixing, adding the procyanidine and the auxiliary materials, performing high-pressure homogenization treatment, and finally preparing different dosage forms. Wherein the preparation of the apple stem cell extract, the cordyceps militaris extract and the lucid ganoderma extract comprises detailed steps. The compound preparation can be used for preparing health care products or medicines for preventing / treating senile nervous system diseases, especially medicines for preventing / improving Alzheimer's symptoms. In addition, the invention also provides a pharmaceutical composition containing the compound preparation and an acetylcholin esterase inhibitor.

The invention relates to the technical field of 3D printing of easy-to-swallow food, in particular to a protein-based nanoparticle gel double-nozzle 3D printing method and equipment, aiming at the nutritional requirements of old people with dysphagia, procyanidine is loaded on protein-based nanoparticles, corn starch, gelatin and the like are combined to construct a composite gel system as a printing wall material, and the printing wall material is used as a printing wall material. Protein, citrus juice and peony seed oil emulsion are used as core materials, and a double-nozzle 3D printing technology is utilized to realize accurate texture regulation and control and personalized nutrition design; the method comprises the steps of protein solution preparation, composite nanoparticle synthesis, procyanidine loading, wall material and core material preparation, double-nozzle printing and the like, the technology breaks through the bottleneck that traditional swallowing food is insufficient in protein strengthening and lacks active ingredients, and the antioxidant functional components and the 3D printing technology are integrated; innovative food with swallowing safety and nutrition targeting is provided for the elderly, and application of protein-based materials in intelligent food manufacturing is promoted.

The invention relates to the technical field of biomedical materials, in particular to hydrogel as well as a preparation method and application thereof. The hydrogel is obtained by crosslinking a polymer framework material, a functional additive and a shielding agent, the polymer framework material comprises any one or more of gelatin, carboxymethyl chitosan, hyaluronic acid, chitosan, collagen, polyvinyl alcohol, sodium carboxymethyl cellulose and sodium alginate; the functional additive comprises any one or more of tannic acid, tea polyphenol, vitamin C and procyanidine; the shielding agent comprises any one or more of barium sulfate, bismuth simple substance and bismuth-containing compound. The hydrogel provided by the invention can effectively isolate radiotherapy rays, reduce oxidative stress reaction, provide a protective barrier for normal tissues in a radiotherapy process and reduce radiation damage, has excellent tissue repair promotion capability, is safe in components, fast in metabolism and adjustable in flowability and adhesion, and is more beneficial to adaptation in rectum or skin tissues.

The utility model discloses equipment for preparing a peanut membrane extract containing proanthocyanidins with the concentration of more than 50%. The equipment comprises a base, the shell is connected with the base, and a containing cavity is defined by the shell and the base; the filter cartridge is accommodated in the accommodating cavity and comprises a cartridge body which is detachably connected with the base; the top cover is arranged on the cylinder body, the top cover is detachably connected with the cylinder body, an inner cavity is defined, and the inner cavity is used for containing a peanut film; the retaining ring is respectively connected with the barrel and the top cover to limit the top cover to move relative to the barrel; and the driving device is arranged on the base, is in transmission connection with the cylinder body and is used for driving the filter cylinder to rotate along the circumferential direction. The device can prevent expanded peanut membranes from entering filtrate, improves the filtering effect, increases the yield, prepares peanut membrane extracts containing proanthocyanidins with the concentration of more than 50%, and plays roles in regulating blood sugar and body fat, resisting aging and the like.

The invention relates to the field of functional additives for daily chemicals, and particularly discloses hydrolyzed procyanidine freeze-dried powder and a preparation method thereof. The hydrolyzed procyanidine freeze-dried powder is prepared by freeze-drying and comprises the following raw materials in parts by weight: 0.1-0.2 part of hydrolyzed procyanidine, 25-35 parts of carnosine, 10-20 parts of a stabilizer, 0.1-0.3 part of acetyl hexapeptide-8 and 45-55 parts of water. The stabilizer is selected from at least one of mannan, trehalose, mannitol, cane sugar, betaine, whey protein, PVP (Polyvinyl Pyrrolidone), PEG (Polyethylene Glycol), glycine, histidine, leucine, sodium alginate, beta-cyclodextrin, maltodextrin and chitosan. The hydrolyzed procyanidine freeze-dried powder has good storage stability, can keep activity for a long time, is still stable after being dissolved in water for a long time, and has less activity loss.

The invention discloses a procyanidine trimer compound, which has a chemical structure as shown in the specification. The hypoglycemic potential of the compound is evaluated through an in-vitro enzyme inhibition experiment, and the result shows that the compound has a remarkable inhibition effect on alpha-amylase, has good water solubility, is derived from natural plant resources, is clear in structure and good in safety, and has a huge application prospect in development of novel natural-source hypoglycemic drugs.

The invention belongs to the field of starch modification processing, and provides a method for preparing starch-polyphenol RS5 type resistant starch. According to the method, through physical-polyphenol composite synergistic modification, a procyanidine polyphenol structure and sweet potato starch are utilized to form a hydrogen bond / hydrophobic effect, starch molecular chains are induced to be directionally rearranged, a resistant crystal structure is stabilized, and the preferable process conditions are as follows: the temperature is 85-90 DEG C, the time is 18-20 minutes, the addition amount of procyanidine is 3-7% of a starch dry basis, and the final resistant starch content reaches 36.39-46.86%. Compared with a traditional method, the raw material utilization rate and the product yield are remarkably improved. The whole process has the advantages of no chemical reagent, simple operation, low equipment cost, and stable resistant starch content of the product.

The invention relates to the field of cell culture and discloses a culture medium for thick-shelled mussel mantle cells and an application thereof. The culture medium comprises a basal culture medium and additives, wherein the additives comprise thick-shelled mussel serum, proanthocyanidins, bovine insulin, growth factors, antibiotics, defensins, mussel mucin and a buffer. The culture medium can be used for in vitro culture of thick-shelled mussel mantle cells and can better maintain the survival and growth of in vitro cultured thick-shelled mussel mantle cells. Defensins in a specific proportion are added to the culture medium, and the best growth and reproduction state can be achieved when the thick-shelled mussel mantle cells are cultured using the culture medium in the specific proportion. The application also provides an application method of the culture medium, which is simple to operate and can produce cultured thick-shelled mussel mantle cells with high cell density, good morphology and high wall adhesion.

The invention belongs to the field of protease extraction, and particularly relates to a method for efficiently extracting bromelain. According to the bromelain-containing mixed solution, the bromelain contained in the bromelain-containing mixed solution obtained by mixing the crushed and quick-frozen pineapples obtained by crushing and quick-freezing with the activity retention agent obtained by freeze-drying and the compound enzyme and treating is high in activity, stable in structure and high in solubility of bromelain contained in the bromelain-containing mixed solution; the adsorption protease composition containing procyanidine, lauryl sodium sulfate and zinc chloride can effectively adsorb bromelain, the auxiliary adsorption suspension capable of forming a film after drying enables bromelain molecules to be in contact with one another more easily, and the adsorption protease composition is added into the auxiliary adsorption suspension for freeze spray drying. The obtained efficient adsorption precipitant can enable the extracted bromelain to be adsorbed and precipitated more efficiently; the bromelain freeze-dried powder extracted by the method for efficiently extracting bromelain is high in enzyme activity, high in purity and strong in stability.

This invention relates to a method for preparing ginkgo leaf extract, the ginkgo leaf extract obtained by the method, and pharmaceutical or food supplements containing the extract.

A composition based on inositol, oligomeric proanthocyanidins and chromium for the prevention and / or treatment of metabolic syndrome and for the primary prevention of cardiovascular diseases, particularly in premenopausal women, is described here.

The present invention discloses a method for brewing yellow rice wine by using proanthocyanidins to reduce the content of ethyl carbamate, belonging to the fields of food safety and fermentation brewing. The present invention solves the problems that the methods for reducing ethyl carbamate in the current yellow rice wine brewing process have certain risks and unpredictability, are prone to cause acidification of yellow rice wine, require a large amount of time, energy and high costs. The method for brewing yellow rice wine by using proanthocyanidins to reduce the content of ethyl carbamate inhibits the production of ethyl carbamate by adding proanthocyanidins during the fermentation and aging processes of yellow rice wine. The method of the present invention can effectively overcome the drawbacks existing in the current ways of degrading ethyl carbamate during the fermentation and aging processes of yellow rice wine, is safe, efficient, saves time and energy, and reduces production costs. The method of the present invention is applicable to the brewing of yellow rice wine.