1272 results about "Proanthocyanidin" patented technology

Metabolic energy capacity enhancing compositions and methods for reducing oxidative stress and improving vitality in a mammal are disclosed. A composition for increasing metabolic energy capacity may be in a palatable liquid formulation or a solid dosage form and typically includes an anti-oxidant containing phytonectar and an energy catalyst. An anti-oxidant may include a polyphenol, anthrocyanin, bioflavonoid, proanthocyanidin, and a xanthone. An energy catalyst may include a mineral, vitamin, co-vitamin, carbohydrate and a lipid. In a presently preferred embodiment a composition includes phytonectar extracts from grape, aloe vera, apple, morinda citrifolia, scullcap, blueberry, prune, cranberry, elderberry, bilberry, and gentain and a mineral blend containing calcium, magnesium, manganese, zinc, chromium, selenium, iron, copper, molybdenum, vanadium, potassium, iodine, and cobalt. A method for increasing metabolic energy capacity in a mammal may include consuming a chemical component having the ability to undergo oxidation, producing free radicals and administering a composition having an anti-oxidant containing phytonectar and an energy catalyst.

Elevated levels of homocysteine have been implicated as an important risk factor for cardiovascular and other diseases. A composition for decreasing levels of plasma homocysteine and a method for administering the composition are provided, the composition containing dextromethorphan (DM), folic acid and vitamins B6 and B12. The composition provides a synergistic therapeutic effect so that lower amounts of the above ingredients may be employed to minimize any undesirable side effects caused by the use of high levels of a component such as DM. Preferred compositions for cardiovascular diseases further include lecithin, vitamin E, betacarotene, procyanidins/flavonoids, trimethylglycine, garlic oil and minerals. Other compositions for treating glaucoma include bilberry, bioflavonoids and beta-carotene and for treating tardive dyskinesia include an antioxidant such a grape seed extract and pine bark extract, lecithin and oligomeric proanthocyanidins. The compositions may be administered using any suitable means such as orally or intravenous.

The invention provides a preparation method for plant enzymes. According to the method, a plurality of plants, vegetables and fruits, seeds, herbal medicines, mushrooms and alga are used as raw materials, natural extraction of plant enzymes is carried out to obtain liquid containing plant active components, and a liquid stock solution of plant enzymes is obtained after fermentation and maturation of the liquid containing plant active components; the obtained liquid stock solution of plant enzymes contains a multienzyme ferment, a protein decomposition enzyme, a fat decomposition enzyme, a starch decomposition enzyme, proanthocyanidin, a plurality of natural vitamins, mineral matters, amino acids, trace elements, etc. The obtained liquid stock solution of plant enzymes is prepared into plant enzyme oral liquid, plant enzyme solid powder or plant enzyme capsules. The preparation method provided in the invention has the following advantages: preparation conditions in the method are simulation of natural generation conditions of enzymes, so preparation theory is scientific; preparation equipment is simple, applicable to large scale production; obtained plant enzymes never contain artificial pigments, synthetic fragrances or antiseptics, and are pure natural. The plant enzymes can be extensively used in health products or cosmetic and make-up products.

The invention provides a composition comprising a matrix of chitosan and a tannin wherein the chitosan is electrostatically bonded to the tannin to form a chitosan-tannin composite material. The chitosan can be partially or fully deacetylated, and the tannin can be a monomeric or an oligomeric proanthocyanidin or a hydrolysable tannin. The chitosan-tannin composite material can be a nanoparticle, a hydrogel film, a bio-foam, or a biogel, or the chitosan-tannin composite material can coat a liposome. The composite materials can be used for drug delivery, for antibacterial and/or antifungal applications, for tissue engineering applications, for wound healing applications, or they can be used as adjuvants for vaccination, including oral vaccinations. The invention also provides methods of preparing the composite materials and their various forms.

The present invention relates to one kind of protocyanidin oligomer and its production process and application in food, health article, feed additive and animal medicine. The protocyanidin oligomer is dimer, trimer and tetramer, and is produced with condensated tannin as material and through oxidizing degradation with hydrogen peroxide or potassium chlorate as oxidant to obtain yellow or brown semi-transparent liquid and subsequent separation and purification. The protocyanidin oligomer of the present invention has powerful antioxidant function and antibiotic function, and my be used in food owing to no astringent taste and no negative effect on the activity of amylase in digestive tract, as feed additive to reduce coccidiosis infection of fowls and low cholesterol content in egg.

A process is disclosed for the production of polyphenol oligomers having n polyphenol monomers, n being an integer from 2-18. The process includes coupling of a protected polyphenol, having protected phenolic hydroxyl groups, with a C-4 functionalized polyphenol monomer. The protected polyphenol may be a protected polyphenol monomer or a protected polyphenol oligomer having 2-17 monomers. Advantageously, polyphenol monomers forming the polyphenol oligomers may be the same or different.

The method for extracting grape-seed oligoproanthocyandin includes the following steps: pulverizing grape-seed, sieving and defatting to obtain grape-seed dregs, extracting the grape-seed dregs by using organic solvent containing inorganic mineral acid, feltering, neutralizing with inorganic alkali, filtering and reduced pressure concentrating to obtain proanthocyanidin crude extract, then adding petroelum ether or chlorform into the crude extract, standing still, filtering and drying to obtain refined proanthocyanidin. The utilization of said method can quickly and simple extract the grape-seeds-waste material of winery and can obtain the invented oligoproanthocyanidin whose content is greater than 60% and yield can be up to 2%.

Cocoa components having enhanced levels of cocoa polyphenols, processes for producing the cocoa components while conserving a significant amount of the cocoa polyphenols, compositions containing the cocoa components or the cocoa polyphenols, and methods of using the cocoa components or the cocoa polyphenols for improving the health of a mammal are described. The cocoa components include partially and fully defatted cocoa solids, cocoa nibs and fractions derived therefrom, cocoa polyphenol extracts, cocoa butter, chocolate liquors, and mixtures thereof. The invention provides processes for extracting fat from cocoa beans and for otherwise processing cocoa beans to yield a cocoa component having conserved concentrations of polyphenols relative to the starting materials.

The invention relates to lycium ruthenicum tablets and a production method thereof. The lycium ruthenicum tablets are prepared by taking lycium ruthenicum as a raw material, selecting, washing, extracting, centrifuging for separation, performing membrane concentration, performing vacuum concentration, weighing, drying, grinding, mixing, pelletizing, drying, straightening and tabletting. The purpose of the invention is to solve the problems of high procyanidine loss and high organic solvent residue content when the lycium ruthenicum tablets are produced by a traditional method. The production method is simple and low in cost, the extraction rate of procyanidine reaches more than 92%, and the prepared lycium ruthenicum tablets are convenient to carry, high in added value and free from organic solvent residues.

The invention discloses a method for extracting oligomeric proanthocyanidins, which comprises the following steps of: extracting a plant raw material containing the oligomeric proanthocyanidins with a solvent; enabling a crude extract to pass through a macroporous adsorbent resin column; eluting with water to remove protein and polysaccharide impurities; carrying out gradient elution with water and one or more selecting from alcohol, methyl alcohol and acetone as an eluant; collecting mixed solution with the volume ratio of n-butyl alcohol, acetic acid and water of 4:1:5; standing for demixing, wherein the solution at upper layer is a developing solvent; and carrying out silica gel thin-layer chromatography, wherein the elution part with the Rf value of 0.2-0.5 on a thin-layer chromatography plate is the oligomeric proanthocyanidins extract. Compared with the prior art, the invention has the advantages that the purity and the yield are both remarkably improved, the yield of the oligomeric proanthocyanidins can reach more than 80 percent, the product purity is no less than 50 percent and is basically more than 80 percent, and the method has simple and convenient process, low cost and easy industrialization.

The invention discloses a making method to crack C-C bond among protocyanin polymer into oligomer protocyanin, which comprises the following steps: dissolving polymer in the solvent; adding 1-10mg/ml degrading liquid in the polymer; adding 5-20% acid catalyst in the degrading liquid; swaying evenly; reacting under 40-90 deg.c for 0.5-2h; insulating air.

The invention relates to an anti-oxidation health-care wine and its production method, wherein the wine is prepared from the oxidation resistant reactive constituents in grape seed and peel extracted with high grade white spirit or brandy with high ethanol content, the the oxidation resistant reactive constituents in grape seed and peel is proanthocyanidin, resveratrol, polydatin, which can effectively remove excess oxygen-derived free radicals in human bodies.

The invention discloses Lycium ruthenicum Murr effective extract and its extraction method and use. The extraction method comprises the following steps of carrying out vacuum drying of Lycium ruthenicum Murr, crushing it, adding 95% of ethanol into the crushed Lycium ruthenicum Murr, carrying out backflow 2 times, wherein each backflow process lasts for 1h, carrying out filtration, carrying out distillation of the filtrate at a temperature of 75 DEG C for concentration, transferring the concentrate into an evaporating dish, carrying out water-bath evaporation, carrying out vacuum drying at a temperature of 70 DEG C for 2h to obtain dry extract, adding methanol into the dry extract until a constant volume is realized, filtering by an organic microporous filter membrane having the aperture size of 0.45 microns and carrying out procyanidine extraction. The Lycium ruthenicum Murr effective extract obtained by the scientific and reasonable extraction method has novel purposes of reducing blood pressure, blood fat and blood sugar. The extraction method provides a novel measure for effective and full utilization of the Lycium ruthenicum Murr effective extract in products for treating or preventing diabetes, hyperlipidemia and hypertension. The extraction method shortens extraction separation time, reduces energy consumption in processes, and effectively reduces a production cost. The Lycium ruthenicum Murr effective extract has high purity, stable performances, fewer extract impurities and good quality. The extraction method adopts pharmaceutical health-care products having antioxidation effects.

The invention relates to a technology for extracting effective components from a natural product and in particular relates to a method for extracting oil and procyanidin from grape seeds. The method comprises the following process steps: preparing grape seeds, grinding, performing ultrasonic extraction to obtain grape seed oil, and performing ultrasonic extraction to obtain procyanidin. The method integrates the characteristics of an ultrasonic extraction method and a double-solvent extraction method, has the characteristics of low solvent dosage, low extraction cost, high extraction efficiency, less influence on the environment and the like, and can be used for effectively avoiding the problem that in the extraction process of the prior art, the bioactivities of grape seed oil and procyanidin are damaged.

The present invention relates to formulations comprising combinations of analgesic/anti-inflammatory, immunomodulating and cartilage-reconstructing agents in particular comprising saligenig, boswellic acid, procyanidins, N-acety-glucosamine and either glucoronic acid or glucoronolactone, for the treatment of rheumatoid arthritis and, more generally, of arthritis conditions.