211 results about "Proanthocyanidin" patented technology

The invention relates to the technical field of high-barrier environment-friendly packaging films, and discloses a high-barrier environment-friendly packaging film with an antibacterial function, the high-barrier environment-friendly packaging film comprises a base layer, a nano composite barrier layer, a bio-based functional layer and an outer protective layer from bottom to top in sequence, and the layers are tightly attached through a coated starch-based adhesive. According to the high-barrier environment-friendly packaging film with the antibacterial function, good biodegradability of polyhydroxyalkanoate adopted in the base layer film, polycaprolactone which is adopted in the nano-composite barrier layer film and has a biodegradable function and konjac glucomannan in the biological functional layer film are utilized; the composite packaging film can be decomposed into carbon dioxide and water by microorganisms in various environments, has excellent flexibility and processability, can adapt to different packaging requirements, provides basic flexibility, structural support and green and environment-friendly effects for the whole packaging film, and has a wide application prospect. The procyanidine arranged in the outer protective layer film provides stronger antibacterial property and water solubility for the whole packaging film.

The invention provides a ginseng exosome anti-aging and anti-oxidation composition and a preparation method thereof, and relates to the field of nursing materials, the ginseng exosome anti-aging and anti-oxidation composition comprises Exo nano-vesicles, procyanidine and cationic liposome, the Exo nano-vesicles are derived from ginseng extracellular fluid, the procyanidine is derived from the cationic liposome, and the cationic liposome is derived from the procyanidine. The ginseng exosome anti-aging and anti-oxidation composition provided by the invention can effectively improve skin wrinkles, enhance skin elasticity, promote collagen synthesis, inhibit collagen degradation and inhibit elastin degradation through the combined action of the Exo nano-vesicles, Pro and cationic lipidosome; degradation of elastin can cause skin to lose resilience, formation of wrinkles is accelerated, and facial skin can be effectively improved and wrinkles can be reduced by promoting synthesis of collagen and inhibiting degradation of elastin.

The invention belongs to the field of nano-medicine and traditional Chinese medicine, and particularly discloses an antioxidant nano-material based on self-assembly of traditional Chinese medicine and copper ions and a preparation method thereof.The nano-material is prepared from BPCu nano-particles formed by self-assembly of berberine and procyanidine B2 under induction of the copper ions, the BPCu nano-particles are further subjected to surface modification through polyvinylpyrrolidone, and the antioxidant nano-material is prepared. And the stably dispersed PVP-coated BPCu nano structure is obtained. The material is small in particle size, uniform in distribution, good in water solubility and storage stability, excellent in free radical scavenging capacity and catalase-like activity and suitable for adjuvant therapy of oxidative stress related diseases, and the preparation method is easy and convenient to operate, does not need an organic solvent and has good industrialization and disease treatment potential.

The invention belongs to the technical field of microorganisms, and relates to a plant lactobacillus NXU-F1 strain and application thereof. The classification name of the bacterial strain is lactobacillus plantarum, the bacterial strain is preserved in Guangdong Microbial Culture Collection Center on June 20, 2025, and the preservation number of the bacterial strain is GDMCC No.66563. The invention also discloses a preparation method of the bacterial strain. The plant lactobacillus is strong in growth capability, has good adaptive capacity to environment, and can obviously increase the content of antioxidant substances when being applied to plant matrix fermentation. The lycium barbarum and grape compound fermented beverage is prepared by fermenting the lycium barbarum and grape compound fermented beverage, the content of polyphenol, flavone, polysaccharide and procyanidine in the beverage is obviously increased, and the increase of resveratrol and ferulic acid is particularly obvious; meanwhile, ester compounds are increased and aldehyde substances are reduced, so that the beverage is endowed with strong longan fruity flavor, and the flavor of harmonious sour and sweet taste and lingering aftertaste is formed.

The invention relates to the field of aquatic feed, and provides a low-temperature adhesive type aquatic feed particle composition and a preparation method thereof. The composition is composed of puffed soybean meal, flour, fish meal, low-temperature directed enzyme, microcrystalline cellulose, modified zein nanoparticles, a protein adhesive and a modified zein ethanol water solution. The preparation method comprises the following specific steps: reacting soybean protein isolate with cross-linking enzyme to generate a protein adhesive, reacting proanthocyanidins with gallic acid to generate gallic acylated proanthocyanidins, and carrying out multi-step treatment on zein. Experimental results show that the composition has excellent water resistance and oxidation resistance, and the growth efficiency and the survival rate of aquatic animals are remarkably improved. The preparation method is simple, the cost is low, heat-sensitive substances in the feed are not damaged, and an economical, efficient and nutrient-rich feed solution is provided for aquaculture.

The invention relates to the technical field of insulin resistance reversal, in particular to a composition with an insulin resistance reversal component and a preparation method thereof.The composition comprises quercetin, procyanidine, malic acid, magnesium carbonate, zinc lactate and cereals, fasting blood glucose, fasting insulin and an insulin resistance index can be reduced through synergistic interaction of all the components, and the insulin resistance index can be reduced; according to the traditional Chinese medicine composition, the insulin sensitivity index is improved, and the problems that in the prior art, traditional Chinese medicine compositions are complex in component, effective components capable of reversing insulin resistance and the synergistic mechanism are unclear, and the content of the effective components in the same medicine is inconsistent due to the influence of the growth environment, so that the treatment effect is unpredictable are solved.

The application belongs to the technical field of food processing, and particularly relates to an oat protein-pectin-proanthocyanidin compound and a preparation method thereof. The oat protein is mixed with water, and an alkali liquor is added to adjust the pH to obtain a protein material solution for medium grinding. Then, pectin is added to the ground protein material solution, and proanthocyanidin powder is added after the pH is adjusted, and secondary medium grinding is performed to obtain an oat protein-pectin-proanthocyanidin solution. Then, hydrochloric acid is slowly added to adjust the pH to 6.8-7.0. Finally, the protein solution is centrifuged, and the supernatant is spray dried to obtain the oat protein-pectin-proanthocyanidin compound. The oat protein-pectin-proanthocyanidin compound prepared by the method is a brand-new protein system, and solves the problems of poor dispersibility, nutritional defects and poor emulsifying property of oat protein, and has a wide application prospect.

The invention relates to the technical field of preparation of Pickering emulsion stabilizers, in particular to a protein-polyphenol-polysaccharide ternary covalent complex as well as a preparation method and application thereof. The method comprises the following steps: step 1, preparing a whey protein isolate aqueous solution, completely hydrating the whey protein isolate aqueous solution, compounding a grape seed oligomeric proanthocyanidins aqueous solution and a hydrated protein aqueous solution, adjusting the pH value, and carrying out stirring reaction and dialysis freeze-drying to prepare a protein-polyphenol binary compound; and 2, compounding the binary compound solution with the lycium barbarum polysaccharide solution, uniformly stirring, carrying out Maillard reaction to obtain a ternary compound solution, and freeze-drying to obtain the protein-polyphenol-polysaccharide ternary compound. The invention provides a non-toxic, harmless and pollution-free natural emulsifier and stabilizer, and simultaneously prepares a Chinese wolfberry seed oil Pickering emulsion capable of loading nutritional ingredients and active substances, thereby providing reference for screening research of the natural emulsifier and protection of nutritional ingredients of Chinese wolfberry seed oil, which are easy to photodecompose and oxidize; the problem that the effect of protein serving as a Pickering emulsion stabilizer in the prior art is poor is solved.

A trace element supplement consisting of lutein, zeaxanthin, astaxanthin, anthocyanins, and proanthocyanidins is designed to improve retinal health in children and adolescents, relieve eye strain, and slow the progression of myopia. The daily dose is 1–20 mg lutein, 0.2–4 mg zeaxanthin, 0.5–8 mg astaxanthin, 10–700 mg taurine, and 0.5–8.5 mg zinc; the nighttime dose is 1–100 mg eyebright extract, 10–300 mg chamomile extract, 1–200 mg anthocyanins, and 1–500 mg proanthocyanidins.

The invention provides weak acid wet toilet paper special for women and a preparation process thereof, and belongs to the technical field of wet toilet paper preparation. The preparation process comprises the following steps: preparing the plant source weak acidity adjusting compound; preparing a bacteriostatic microcapsule compound; and preparing the weakly acidic wet toilet paper. The weakly acidic wet toilet paper prepared by the invention can relieve redness and pruritus of private skin caused by friction and secretion stimulation and enhance the skin barrier function, and an'instant bacteriostasis-long-acting regulation 'dual path is formed by the bacteriostatic component released by the microcapsule, the cranberry proanthocyanidin and the lactic acid bacteria metabolite, so that the recurrence rate of vaginitis is reduced.

The invention relates to the technical field of 3D printing of easy-to-swallow food, in particular to a protein-based nanoparticle gel double-nozzle 3D printing method and equipment, aiming at the nutritional requirements of old people with dysphagia, procyanidine is loaded on protein-based nanoparticles, corn starch, gelatin and the like are combined to construct a composite gel system as a printing wall material, and the printing wall material is used as a printing wall material. Protein, citrus juice and peony seed oil emulsion are used as core materials, and a double-nozzle 3D printing technology is utilized to realize accurate texture regulation and control and personalized nutrition design; the method comprises the steps of protein solution preparation, composite nanoparticle synthesis, procyanidine loading, wall material and core material preparation, double-nozzle printing and the like, the technology breaks through the bottleneck that traditional swallowing food is insufficient in protein strengthening and lacks active ingredients, and the antioxidant functional components and the 3D printing technology are integrated; innovative food with swallowing safety and nutrition targeting is provided for the elderly, and application of protein-based materials in intelligent food manufacturing is promoted.

The invention relates to the technical field of biomedical materials, in particular to hydrogel as well as a preparation method and application thereof. The hydrogel is obtained by crosslinking a polymer framework material, a functional additive and a shielding agent, the polymer framework material comprises any one or more of gelatin, carboxymethyl chitosan, hyaluronic acid, chitosan, collagen, polyvinyl alcohol, sodium carboxymethyl cellulose and sodium alginate; the functional additive comprises any one or more of tannic acid, tea polyphenol, vitamin C and procyanidine; the shielding agent comprises any one or more of barium sulfate, bismuth simple substance and bismuth-containing compound. The hydrogel provided by the invention can effectively isolate radiotherapy rays, reduce oxidative stress reaction, provide a protective barrier for normal tissues in a radiotherapy process and reduce radiation damage, has excellent tissue repair promotion capability, is safe in components, fast in metabolism and adjustable in flowability and adhesion, and is more beneficial to adaptation in rectum or skin tissues.

The utility model discloses equipment for preparing a peanut membrane extract containing proanthocyanidins with the concentration of more than 50%. The equipment comprises a base, the shell is connected with the base, and a containing cavity is defined by the shell and the base; the filter cartridge is accommodated in the accommodating cavity and comprises a cartridge body which is detachably connected with the base; the top cover is arranged on the cylinder body, the top cover is detachably connected with the cylinder body, an inner cavity is defined, and the inner cavity is used for containing a peanut film; the retaining ring is respectively connected with the barrel and the top cover to limit the top cover to move relative to the barrel; and the driving device is arranged on the base, is in transmission connection with the cylinder body and is used for driving the filter cylinder to rotate along the circumferential direction. The device can prevent expanded peanut membranes from entering filtrate, improves the filtering effect, increases the yield, prepares peanut membrane extracts containing proanthocyanidins with the concentration of more than 50%, and plays roles in regulating blood sugar and body fat, resisting aging and the like.

The invention relates to the field of functional additives for daily chemicals, and particularly discloses hydrolyzed procyanidine freeze-dried powder and a preparation method thereof. The hydrolyzed procyanidine freeze-dried powder is prepared by freeze-drying and comprises the following raw materials in parts by weight: 0.1-0.2 part of hydrolyzed procyanidine, 25-35 parts of carnosine, 10-20 parts of a stabilizer, 0.1-0.3 part of acetyl hexapeptide-8 and 45-55 parts of water. The stabilizer is selected from at least one of mannan, trehalose, mannitol, cane sugar, betaine, whey protein, PVP (Polyvinyl Pyrrolidone), PEG (Polyethylene Glycol), glycine, histidine, leucine, sodium alginate, beta-cyclodextrin, maltodextrin and chitosan. The hydrolyzed procyanidine freeze-dried powder has good storage stability, can keep activity for a long time, is still stable after being dissolved in water for a long time, and has less activity loss.

The invention discloses a procyanidine trimer compound, which has a chemical structure as shown in the specification. The hypoglycemic potential of the compound is evaluated through an in-vitro enzyme inhibition experiment, and the result shows that the compound has a remarkable inhibition effect on alpha-amylase, has good water solubility, is derived from natural plant resources, is clear in structure and good in safety, and has a huge application prospect in development of novel natural-source hypoglycemic drugs.

The invention belongs to the field of starch modification processing, and provides a method for preparing starch-polyphenol RS5 type resistant starch. According to the method, through physical-polyphenol composite synergistic modification, a procyanidine polyphenol structure and sweet potato starch are utilized to form a hydrogen bond / hydrophobic effect, starch molecular chains are induced to be directionally rearranged, a resistant crystal structure is stabilized, and the preferable process conditions are as follows: the temperature is 85-90 DEG C, the time is 18-20 minutes, the addition amount of procyanidine is 3-7% of a starch dry basis, and the final resistant starch content reaches 36.39-46.86%. Compared with a traditional method, the raw material utilization rate and the product yield are remarkably improved. The whole process has the advantages of no chemical reagent, simple operation, low equipment cost, and stable resistant starch content of the product.

The invention relates to the field of cell culture and discloses a culture medium for thick-shelled mussel mantle cells and an application thereof. The culture medium comprises a basal culture medium and additives, wherein the additives comprise thick-shelled mussel serum, proanthocyanidins, bovine insulin, growth factors, antibiotics, defensins, mussel mucin and a buffer. The culture medium can be used for in vitro culture of thick-shelled mussel mantle cells and can better maintain the survival and growth of in vitro cultured thick-shelled mussel mantle cells. Defensins in a specific proportion are added to the culture medium, and the best growth and reproduction state can be achieved when the thick-shelled mussel mantle cells are cultured using the culture medium in the specific proportion. The application also provides an application method of the culture medium, which is simple to operate and can produce cultured thick-shelled mussel mantle cells with high cell density, good morphology and high wall adhesion.

The invention belongs to the field of protease extraction, and particularly relates to a method for efficiently extracting bromelain. According to the bromelain-containing mixed solution, the bromelain contained in the bromelain-containing mixed solution obtained by mixing the crushed and quick-frozen pineapples obtained by crushing and quick-freezing with the activity retention agent obtained by freeze-drying and the compound enzyme and treating is high in activity, stable in structure and high in solubility of bromelain contained in the bromelain-containing mixed solution; the adsorption protease composition containing procyanidine, lauryl sodium sulfate and zinc chloride can effectively adsorb bromelain, the auxiliary adsorption suspension capable of forming a film after drying enables bromelain molecules to be in contact with one another more easily, and the adsorption protease composition is added into the auxiliary adsorption suspension for freeze spray drying. The obtained efficient adsorption precipitant can enable the extracted bromelain to be adsorbed and precipitated more efficiently; the bromelain freeze-dried powder extracted by the method for efficiently extracting bromelain is high in enzyme activity, high in purity and strong in stability.

This invention relates to a method for preparing ginkgo leaf extract, the ginkgo leaf extract obtained by the method, and pharmaceutical or food supplements containing the extract.

The present invention discloses a method for brewing yellow rice wine by using proanthocyanidins to reduce the content of ethyl carbamate, belonging to the fields of food safety and fermentation brewing. The present invention solves the problems that the methods for reducing ethyl carbamate in the current yellow rice wine brewing process have certain risks and unpredictability, are prone to cause acidification of yellow rice wine, require a large amount of time, energy and high costs. The method for brewing yellow rice wine by using proanthocyanidins to reduce the content of ethyl carbamate inhibits the production of ethyl carbamate by adding proanthocyanidins during the fermentation and aging processes of yellow rice wine. The method of the present invention can effectively overcome the drawbacks existing in the current ways of degrading ethyl carbamate during the fermentation and aging processes of yellow rice wine, is safe, efficient, saves time and energy, and reduces production costs. The method of the present invention is applicable to the brewing of yellow rice wine.

The invention relates to a method for preparing a Ginkgo biloba leaf extract highly concentrated in proanthocyanidins, and practically free of flavonoids and terpene trilactones. The invention also relates to the use of cheese fungal strains such as Penicillium Roquefortii PA and Geotrichum Candidum Geo 15, to catabolize high molecular weight proanthocyanidin polymers into small molecules in order to have beneficial effects on health.

The present invention relates to a functional composition and uses thereof, and in particular towards a composition that maintains or improves mental clarity. The composition includes a combination of at least two of: a pine bark extract containing proanthocyanidin(s); a berryfruit extract containing anthocyanin(s); and a source of L-theanine. The invention also relates to methods of use and treatment of said composition.

This invention relates to the field of feed additive technology, specifically to a Bacillus subtilis composition for improving animal intestinal health and its preparation method. It comprises the following raw materials: Bacillus subtilis engineered bacterial powder, cinnamaldehyde microcapsules, proanthocyanidins B2, selenium-enriched yeast culture, glycoterpenes, trehalose, and a carrier. The core of this invention lies in using Bacillus subtilis EhrBS-9 (CGMCC No. 24947) as the strain, constructing a dual-function engineered bacterium with tolerance and transformation through gradient cinnamaldehyde domestication and cad gene integration. This, combined with the intestinal-targeted delivery of cinnamaldehyde microcapsules, barrier strengthening of proanthocyanidins B2, and the construction of a multidimensional anti-stress network of selenium-enriched yeast, glycoterpenes, and trehalose, forms a synergistic mechanism of gut microbiota regulation, immune enhancement, and stress buffering. This addresses the industry pain point of insufficient synergistic effects of existing feed additives in terms of high-efficiency antibacterial activity, safe immune regulation, root-cause anti-stress, and ecological safety.

The invention discloses a feed additive and compound feed for improving the muscle quality of litopenaeus vannamei, and belongs to the technical field of aquatic feed. The feed additive comprises the following air-dried substance components in percentage by weight: 1%-30% of procyanidine, 1%-30% of levodopa and 40%-98% of broad bean powder, the compound feed comprises the feed additive and a main feed composed of fish meal, chicken meal, soybean meal, soybean protein concentrate, peanut meal, wheat middling, squid paste, fish oil, soybean lecithin, vitamin premix, mineral premix and the like. According to the litopenaeus vannamei compound feed, the synthesis of muscle collagen is promoted through the procyanidine, the muscle hardness, chewiness and shearing force are improved, meanwhile, the content of free amino acid is increased through the levodopa, the wind taste of the muscle is improved, and the antioxidant capacity and the water retention capacity of the muscle are improved, so that the muscle quality of the litopenaeus vannamei is improved.

The invention belongs to the technical field of food safety, and relates to application of peanut red skin proanthocyanidin nano-liposome in inhibition of salmonella typhimurium, and the peanut red skin proanthocyanidin nano-liposome causes cell death by causing permeability change of cell membranes and cell walls of salmonella typhimurium. According to the present invention, the inherent limitation of the natural antibacterial substance PSPc is overcome through the efficient delivery system of the nano-liposome, such that the salmonella typhimurium inhibition activity of the nano-liposome can be completely performed and durably maintained, the method is efficient and safe, the application potential in the food preservation aspect is provided, and the value-added utilization of the peanut resource is improved.

The invention belongs to the field of extraction, processing and application of natural plant products, and particularly relates to a preparation method of a grape seed extract and application of the grape seed extract in preparation of a composition for preventing hair loss and growing hair. Tests prove that the grape seed extract can remarkably promote proliferation of hair papilla cells, inhibit apoptosis of the hair papilla cells and remarkably promote expression of factors representing that hair papilla enters an active cycle, is beneficial to inducing or maintaining the growth period of hair follicles and achieving self-rebuilding of the hair follicles, has good effects of preventing hair loss and growing hair, and can be used for preventing hair loss. A new way is provided for development and utilization of the grape seed extract.

The invention discloses procyanidine B2G2 from purple sweet potato Ningzi No.4 and application thereof, and belongs to the technical field of biological medicine, the molecular formula of the procyanidine B2G2 is C44H34O20, and the molecular weight of the procyanidine B2G2 is 882.736 Da. The procyanidine B2G2 remarkably relieves acute lung injury ALI by inhibiting inflammatory response and ferroptosis induced by klebsiella pneumoniae KP; experiments show that B2G2 can reduce the lung tissue injury score, the lung wet / dry ratio, the expression of inflammatory factors TNF-alpha, IL-6 and IL-1beta and the bacterial load, and up-regulate the expression of ferroptosis related proteins GPX4, SLC7A11 and HO-1; in addition, B2G2 is non-toxic to liver and kidney functions and has good safety, and the application provides a new drug candidate scheme for preparation of drugs for treating acute lung injury.

The invention discloses a natural plant polyphenol-peptide compound applied to mouth wash. The compound consists of plant polyphenols such as procyanidine and catechin in specific parts by weight, and five sections of small molecule peptides derived from soybeans, corns and the like. By optimizing extraction, separation and compounding processes, the polyphenol and the peptide have synergistic interaction. The prepared mouthwash has the functions of efficiently resisting bacteria (harmful bacteria are reduced by 85%-95%), resisting inflammation (inflammatory factors are remarkably reduced), repairing enamel (hardness is improved by 42%), freshening breath (VSC concentration is reduced to 18 ppb) and the like. Compared with traditional mouthwash, the mouthwash overcomes the defects of component irritation, single function and the like, adopts a green process to ensure activity, and is good in stability and good in taste.

The invention discloses fat-soluble oligomeric procyanidine as well as a preparation method and application thereof, and belongs to the technical field of high-value processing of food byproducts. Oleic anhydride is utilized to modify the proanthocyanidin oligomer, and a fatty acid chain is introduced to the proanthocyanidin oligomer, so that the proanthocyanidin oligomer obtains good fat solubility, and meanwhile, the oxidation resistance of the proanthocyanidin oligomer is also improved. The modified procyanidine oligomer has the advantages of large particle size, high fat solubility, good in-vitro digestion stability, difficult degradation and easy absorption, overcomes the problem of low bioavailability of the existing procyanidine oligomer, and has good medical value and application prospect.

The invention relates to the technical field of procyanidine extraction, and provides a green extraction method of procyanidine in grape pips, which comprises the following steps: carrying out physical wall breaking treatment on dry grape pips; mixing the pretreated grape seeds with the eutectic solvent precursor liquid, and carrying out solid-liquid separation to obtain a clear extracting solution; adding an azobenzene chitosan solution into the clarified extracting solution, mixing under a dark condition, irradiating by adopting light with a first specific wavelength to form a compound precipitate, and separating to obtain a precipitate; dispersing the compound precipitate in an aqueous medium, irradiating with light with a second specific wavelength to release the proanthocyanidins from the compound, separating to obtain a supernatant containing the proanthocyanidins, and recycling regenerated azobenzene chitosan; and concentrating and drying the supernate to obtain a procyanidine product. According to the technical scheme, the extraction efficiency and purity of the procyanidine are improved, and efficient selective precipitation separation and mild release are realized by utilizing the photoresponsive carrier.