The invention discloses Lycium ruthenicum Murr effective extract and its extraction method and use. The extraction method comprises the following steps of carrying out vacuum drying of Lycium ruthenicum Murr, crushing it, adding 95% of ethanol into the crushed Lycium ruthenicum Murr, carrying out backflow 2 times, wherein each backflow process lasts for 1h, carrying out filtration, carrying out distillation of the filtrate at a temperature of 75 DEG C for concentration, transferring the concentrate into an evaporating dish, carrying out water-bath evaporation, carrying out vacuum drying at a temperature of 70 DEG C for 2h to obtain dry extract, adding methanol into the dry extract until a constant volume is realized, filtering by an organic microporous filter membrane having the aperture size of 0.45 microns and carrying out procyanidine extraction. The Lycium ruthenicum Murr effective extract obtained by the scientific and reasonable extraction method has novel purposes of reducing blood pressure, blood fat and blood sugar. The extraction method provides a novel measure for effective and full utilization of the Lycium ruthenicum Murr effective extract in products for treating or preventing diabetes, hyperlipidemia and hypertension. The extraction method shortens extraction separation time, reduces energy consumption in processes, and effectively reduces a production cost. The Lycium ruthenicum Murr effective extract has high purity, stable performances, fewer extract impurities and good quality. The extraction method adopts pharmaceutical health-care products having antioxidation effects.