The invention discloses a space-borne real-time occultation prediction method, which comprises first obtaining the position velocity of the spacecraft according to the positioning equipment of the occultation detector, and calculating the orbital parameters of the spacecraft; and then calculating the orbital parameters of the spacecraft and all navigation stars after 10s position, and calculate the pitch angle, azimuth angle, tangent point height and antenna azimuth angle of all navigation stars, and judge whether the obtained pitch angle Elv, tangent point height Hight and antenna azimuth angle meet the threshold of occultation events, if satisfied , then extrapolate the time for 30s and 1min, and repeat the above calculation and judgment process respectively. If all are satisfied, it is determined that the navigation star is an occultation. The present invention judges occultation events by adopting continuous arc segments by inertial navigation equipment, thereby enhancing the accuracy of forecast results, the method is simple and easy, and has important application value for real-time forecast.