5780 results about "Oil phase" patented technology

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, at least one anti-inflammatory agent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

A stable topical alcohol-free aerosol foam containing one or more keratolytic agents is provided. The foam-forming formulation is an emulsion which contains an HFA propellant and one or more keratolytic agents. The emulsion has an oil phase and an aqueous, i.e. water-containing, phase. The active agent(s) may be present in either phase of the emulsion or dispersed in the emulsion. The oil phase may consist at least in part of the HFA propellant. Either or both of the oil phase and the aqueous phase may contain one or more surfactants, emulsifiers, emulsion stabilizers, buffers, and/or other excipients. The foam is stable on the skin, for example, for at least 5 minutes at body temperature, preferably at least 20 minutes at body temperature, and disappears into the skin upon rubbing or after prolonged standing. In one embodiment, the formulation contains an HFA propellant which does not contain additional co-solvents or co-propellants. The formulations demonstrate reduced intensity of the odor and/or color associated with the keratolytic agent(s) as compared to conventional formulations containing keratolytic agents.

An aqueous peroxide composition for coloring or lightening hair comprising (a) 1-99% of an aqueous phase containing (ii) 1-55% by weight of the total composition of water, (ii) 1-45% hydrogen peroxide, and (iii) a water soluble cosolvent; and (b) 0.1-60% of an oil phase; and (c) 1-65% of an organic, amphiphilic, surface active ingredient capable of interacting with the water phase and the oil phase to form lyotropic liquid crystals containing said water phase ingredients; a method for coloring or lightening hair using the peroxide composition, and a method for reducing the amount of time necessary to permanently color hair using the peroxide composition.

The invention relates to a method of depositing a benefit agent on a keratinous surface, said method comprising topically applying to said surface an effective amount of a ringing gel composition comprising (a) a surfactant phase; (b) an oil phase; and (c) a benefit agent.

Nanoemulsion compositions with low toxicity that demonstrate broad spectrum inactivation of microorganisms or prevention of diseases are described. The nanoemulsions contain an aqueous phase, an oil phase comprising an oil and an organic solvent, and one or more surfactants. Methods of making nanoemulsions and inactivating pathogenic microorganisms are also provided.

Personal care composition comprising from about 5% to about 75% of an oil phase; an aqueous phase; from about 0.1% to about 2% of a polymeric thickener; and a skin care active; wherein said composition comprises at least two separate phases, and after agitation and dispensation from a suitable container containing a suitable propellant, forms stable foam.

Sprayable, anhydrous and physically/chemically stable dermatological/pharmaceutical compositions, well suited for the treatment of a variety of dermatological disorders, notably psoriasis, contain: a) a therapeutically effective amount of a solubilized corticoid, notably dissolved clobetasol propionate; b) a therapeutically effective amount of a solubilized vitamin D derivative, notably dissolved calcitriol; and c) an oily phase which comprises one or more oils; formulated into d), a sprayable and topically applicable, dermatologically/pharmaceutically acceptable vehicle therefor.

The present invention relates to an oil-in-water emulsion topical delivery system comprising an oil phase; an aqueous phase; phenoxyethanol; an effective exfoliatingamount of a hydrophobic hydroxycarboxylic acid; a non-ionic emulsifier having an HLB of from about 7 to about 10; and at least one skin-supporting ordermatopharmaceutically active agent.

A composition comprising purified water using ozonation, ionization, or distillation or any combination thereof wherein alcohol may be substituted for, or combined with water at least one emollient including but not limited to chitosan, and aloe vera gel, individually or in any combination; an oil component with spf boosting agents including but not limited to; ethyl macadamiate, non-toxic silicone oil and essential oils, butter milk, waxes impregnated with inorganic sun-block or sunscreen agent and organic/inorganic micronized particles, wood powder and bentonite clay, keratin, either individually or in any combination; at least one inorganic sun-block or sunscreen agent including any metal oxide, glass microsphere, silica and silica compound, and optionally metal oxide pigments with particles that are micronized, submicronized, nanoparticle sized, or otherwise individually or in any combination that can be homogenized in either a water phase, a water-aloe phase, an oil phase or any phase of said composition; at least one emulsifier wherein said emulsifier includes but is not limited to a phospholipid and/or liposome or an aloe vera gel or an ester of coconut oil individually or in any combination, for emulsifying the water, water-aloe, or oil phase in combination with an homogenizer; where any of components are preferably mixed with an homogenizer and where an appropriate thickening agent including but not limited to xanthan gum, carageenan, either individually or in any combination is added as required.

The present invention provides novel dietary supplement compositions based on the use of a particular oil phase which comprises of Coenzyme Q10 and optionally other lipophilic dietary ingredients of low water solubility and a liquid mixture which comprises one or more emulsifiers, a fatty acid monoester formed between an short chain alcohol of C1 to C4 chain length and a saturated, or mono-unsaturated, or di-unsaturated (both conjugated and non-conjugated) fatty acid of C6 to C24 chain length, or medium chain mono-/di-esters, or the mixture of above. The composition is in a form of self-emulsifiable in the aqueous medium, for example, a simulated gastric fluid, which should provide a high oral bioavailability for the lipophilic dietary ingredients.

Compositions in the form of a spray contain a pharmaceutical active agent, at least one volatile silicone and a non-volatile oily phase, formulated into a physiologically acceptable medium, are well suited for improved transdermal administration in cosmetics and dermatology.

The invention discloses spherical integral macroporous alumina and a preparation method thereof. The method comprises the following steps of: uniformly mixing polymer microspherical emulsion, alumina sol and a coagulant in a certain ratio, and dispersing the mixture in an oil phase to obtain W/O liquid drops; heating the miscible phase system to make the alumina sol in an aqueous phase gelatinized into spheres; separating out the formed gel microspheres from the oil phase; and ageing in an ammonia water medium, drying, and roasting to obtain the spherical integral macroporous alumina. The macropore size of the alumina is uniform and controllable in a range of less than 1 mu m, spherical particles have controllable size and high mechanical strength, and the forming process is simple and feasible, and is suitable for mass preparation.

The invention relates to a microemulsion-type fracture acidizing cleanup additive, and a preparation method and application thereof, belonging to the technical field of petrochemical industry. The microemulsion-type fracture acidizing cleanup additive is prepared from the following components in percentage by weight:5-10% of surfactant, 2-8% of cosurfactant, 35-45% of oil phase, 35-45% of water phase and 3-10% of inorganic electrolyte. The microemulsion-type fracture acidizing cleanup additive provided by the invention has a function of restoring reservoir permeability; and compared with the existing cleanup additive system, the microemulsion-type fracture acidizing cleanup additive provided by the invention can reduce the degree of reservoir damage, which is caused by incompatibility of water locks, residues and formation fluids in the wellbore area of an oil well in the fracture acidizing process of an oil and gas well, by more than 50%.

Method of treating a subterranean formation, comprising (A) injecting down a well bore into the formation an admixture of (a) an emulsion having an internal aqueous phase comprising a water-soluble oil of gas field chemical or an aqueous dispersion of a water-dispersible oil or gas field chemical and an external oil phase comprising a liquid hydrocarbon and an oil-soluble surfactant and (b) a demulsifier comprising a solution of a surfactant having a cloud point temperature of above 40° C. Alternatively, the method comprises separately injecting down a well bore into the formation emulsion (a) and demulsifier (b) and generating an admixture of emulsion (a) and demulsifier (b) within the formation.

The invention relates to a harsh oil deposit reversed-phase microemulsion profile-control flooding system and a preparation method thereof. The problems in the prior art that the initial particle size of the product is improper and polymeric microspheres are poor in expansibility under high-temperature high-salt conditions are mainly solved. The harsh oil deposit reversed-phase microemulsion profile-control flooding system disclosed by the invention comprises the following components in parts by weight of microemulsion: 20-70 parts of an oil-soluble solvent, 5-20 parts of an emulsifier and a co-emulsifier, 20-70 parts of a polymer aqueous phase containing acrylamide and other temperature-resistant salt-resistant comonomers. According to the technical scheme, a semi-continuous reaction method is adopted, the aqueous phase containing acrylamide and other temperature-resistant salt-resistant comonomers is added into an oil phase containing the emulsifiers in batches, and a hydrophobic monomer is added, so that the problems are solved, the prepared polyacrylamide reversed-phase microemulsion is directly compounded or is compounded with other oil field chemicals to be applied to such field applications for improving oil recovery as depth profile control, water plugging and displacement in tertiary oil recovery of a harsh oil deposit.

An oil-in-water emulsion composition for wet-wipes delivering a particulate skin health benefit ingredient in the oil phase. A process for making an oil-in-water emulsion composition in which the oil phase is first made as a concentrate and then diluted in water.

Disclosed are multilayered liposomes for transdermal absorption and a method of preparing the liposomes. The multilayered liposomes are prepared using a mixture of oil-phase components comprising squalane, sterols, ceramides, neutral lipids or oils, fatty acids and lecithins, is 200 to 5000 nm in particle size, and is capable of entrapping a physiologically active substance. The multilayered liposomes entrap a larger amount of a physiologically active substance and are structurally stable when encapsulating the physiologically active substance, compared to unilamellar liposomes. Also, they are prepared by a simple and cost-effective process not using a high-pressure homogenizer but using a general homo mixer. Further, since the multilayered liposomes are prepared in a larger size than the intercellular spaces in the stratum corneum, they overcome the tension of surrounding cells when passing through the intercellular spaces and are thus able to penetrate into the dermal layer, compared to nano-sized unilamellar liposomes. Thus, the multilayered liposomes are useful for enhancing the transdermal absorption of physiologically active substances.

A preparation method for porous microspheres of a biodegradable polymer is provided. The method comprises the following steps: (a) dissolving a biodegradable polymer in an organic solvent to form an oil phase of 1-30% (g/ml) concentration; (b) selecting a pore-forming agent 1-50% of the biodegradable polymer in the step (a) and dissolving the pore-forming agent in water to form an internal water phase; (c) adding dropwise the internal water phase into the oil phase at a volume ratio of (1-30):100, and stirring to form a primary emulsion; (d) preparing a polyvinyl alcohol aqueous solution of 0.5-10% (g/ml) concentration, which serves as an external water phase; (e) pouring the primary emulsion into the external water phase at a volume ratio of (3-30):100, stirring or performing ultrasonic treatment to form a double-emulsion, and allowing the polymer in the double-emulsion to solidify, thereby forming microspheres; (f) freeze-drying the microspheres to obtain the final product. The obtained porous microspheres of the biodegradable polymer have high porosity, large specific surface area and good adsorption and encapsulation properties; and are used for the adsorption and encapsulation of unstable protein drugs, polypeptide drugs and growth factors and can retain pharmaceutical activity and effectiveness thereof.

Antiperspirant emulsion products with improved antiperspirant efficacy and processes for making them are provided. In one embodiment, an antiperspirant emulsion product comprises a water-in-oil emulsion having a water phase and an oil phase. The water phase comprises an activated aluminum sesquichlorohydrate active system and the oil phase comprises cetyl PEG/PPG-10/1 dimethicone and a hydrophobic carrier.

The invention relates to a method and system for establishing a multilayer oil pool inter-well connectivity model. The multilayer oil pool inter-well connectivity model capable of simulating oil and water dynamic states is established oriented to the limitation that by means of a current connectivity model, only the dynamic change of production liquid can be predicted, the dynamic states of the oil phase and the water phase cannot be calculated respectively, and connectivity analysis cannot be carried out layer by layer. According to the model, an oil pool system is layered and scattered into a series of inter-well communication units, matter balance equation calculation is carried out with the inter-well communication units as simulating objects, pressure solving and inter-well flow calculation are achieved, an inter-well saturation degree tracking calculating method is established with the combination of the lead edge boosting theory, and the output dynamic states of oil and water of all layers at well points are obtained; a model parameter inversion method is established in a fitting mode through dynamic states based on a random disturbance approximation method, a projection gradient method and the like. Layered inter-well flow distribution coefficients, single well longitudinal production liquid and production oil splitting coefficients and other information can be obtained in real time, the oil pool plane, the longitudinal oil and water flow relation and the production measure change can be more accurately reflected to guide the practical production of an oil field.

The present invention relates to a multi-phase cosmetic composition for application to the body, which has a liquid and transparent appearance, becomes a homogeneous mixture after being stirred, the phases raps idly separating when at rest. The composition according to the present invention comprises at least one oily phase and at least one aqueous phase, further comprising a polyol, the oily phase comprising a mixture of at least one mineral oil and at least one vegetable oil, and the aqueous phase comprising a water-soluble salt.

The invention relates to a heavy oil and biomass hydrogenation coliquefaction treatment process in which one or two of heavy oil and biomasses are used as raw materials in vacuum gas oil with the distillation range of 360-540 DEG C and FCC (Fluid Catalytic Cracking) oil slurry. In the process, an oil-soluble transition metal organic compound with hydrogenation activity is used as a catalyst, dimethyl sulfide is used as a vulcanizing agent, a full-back-mixing type empty barrel reactor is used as a slurry column hydrogenation reactor, the reaction temperature is uniform, and the structure is simple. By using the process, the conversion rate of the biomasses can be up to over 90wt% at lower hydrogen pressure of 4-8MPa and the temperature of 370-430 DEGC, and the yield of oil phases is up to over 70wt%. A dispersive hydrogenation catalyst adopted in the process can be used for greatly reducing the quantity of green cokes and taking a better deoxidization effect on the biomasses.

The invention relates to a polymer nanomicrosphere product with uniform and controllable size and a preparation method thereof. The preparation method comprises the following steps: preparing polymerizable olefine monomers, an initiator, assistants and the like into an oil phase, and preparing water, a stabilizer, an emulsifier and the like into a water phase; and mixing the oil phase and water phase into an O/W pre-emulsion, quickly passing the pre-emulsion through a uniform-pore-size microporous membrane under pressure to form a uniform-particle-size O/W emulsion, and polymerizing and curing emulsion droplets in the emulsion into the uniform-particle-size polymer nanomicrospheres. The average particle size of the microspheres can be controlled within the range of tens of nanometers to 50 micrometers, and the particle size distribution coefficient C.V. is smaller than 20%. The method has the advantages of simple steps, favorable batch repetitiveness, uniform and controllable particle size, no need of subsequent screening and the like, is easy to control, can easily implement large-scale production, and therefore, has the characteristics of fewer emissions and low preparation cost.

The invention discloses a preparation method of an alumina porous microsphere. The preparation method comprises the following steps: 1) dissolving a surfactant in deionized water, stirring the solution, and using the solution as a water phase; 2) mixing a chelating agent, an alumina precursor and octanol, stirring the materials, and using the mixture as an oil phase; 3) adding Span80 and a pore-forming agent to the oil phase, and stirring the materials; 4) pouring the clear oil phase obtained in the step 3) into the water phase, and continuously stirring and emulsifying the materials; 5) carrying out vacuum filtration on the product obtained in the step 4), and washing and then drying the obtained filter cake, thus obtaining the alumina porous microsphere. The microsphere has an internally closed macroporous structure and has a microsphere dimension of 1-100mu m and an internally closed pore diameter of 50nm-5mu m.

The invention provides a piece of equipment and a method for extracting volatile essential oil from natural perfume plants by using the technology of reduced pressure steam distillation extraction. The equipment provided in the invention comprises a steam distillation system and a vacuum system, wherein the steam distillation system is composed of a steam generator, a material retort, a condenser, an oil-water separator and connecting pipelines, and the vacuum system comprises a vacuum unit or a suction pump, a pressure regulator valve, connecting pipelines and the like. The method comprises the following steps that: plant raw materials to be extracted for essential oil in the material retort is controlled to be at a certain temperature and under certain pressure so as to reduce changes of aroma components in perfume plants in the process of extraction as much as possible; extracted volatile components of essential oil is mixed with steam to form mixed steam of water and oil; the mixed steam enters into the condenser for condensation and then enters into the oil-water separator for separation; an oil phase is collected after separation and the oil phase is plant essential oil; the separated water phase is flower water. The essential oil and flower water obtained by the extraction method have pure aroma, suffer little loss for head volatile thereof, and are applicable to the industries of perfumes, essence, cosmetics, daily chemicals, etc.

The present invention relates to a composition containing anionic, amphoteric, cationic or non-ionic stable high solid polymeric emulsions wherein the solids content is equal to or greater then 35%, the emulsion particle size is less than or equal to 0.5 microns and the surfactant level ranges from 2 to 9 percent. The present invention also relates to a method for preparing said high solid polymeric emulsions, which process comprises the steps of (a) admixing; (i) an oil phase composition comprising at least one hydrocarbon liquid; (ii) an effective amount of a surfactant or mixture of surfactants or mixture of surfactant and co-surfactant; (vii) an aqueous phase comprising at least one monomer selected from the group consisting of ethylenically unsaturated cationic monomers, ethylenically unsaturated anionic monomers, ethylenically unsaturated amphoteric monomers and ethylenically unsaturated nonionic monomers, and optionally, (viii) at least one cross-linking agent, so as to form an inverse emulsion; (b) heating the inverse emulsion formed in step (a) to a temperature of about 28 to about 50° C.; (c) degassing the heated inverse emulsion formed in (b); and, (d) polymerizing the monomer or monomers of the emulsion formed in (c) to form the polymeric inverse emulsion.

A stable, liquid concentrate herbicidal composition is provided. The composition comprises a water-soluble herbicide in a continuous aqueous phase and an oil-soluble herbicide in a discontinuous oil phase.

PEG-free, cold-preparable, prolonged-stability, low-viscosity, fine oil-in-water emulsions, their preparation from preferably clear oil phases or via preferably clear to transparent microemulsion-like concentrates, the corresponding oil phases or microemulsion-like concentrates and the use of the inventive emulsions for producing cosmetic, dermatological, pharmaceutical or industrial formulations, especially for the production of impregnating emulsions for wet wipes or for sprayable care emulsions are provided.

The invention relates to a method for preparing methylbenzene or dimethylbenzene by alkylating benzene with methanol, comprising the following steps: raw material benzene and recycle benzene rectified to be recovered are mixed together with the methanol, mixed materials exchange heat with materials on an outlet of an alkylation reactor, and then the mixed materials are heated to achieve alkylation reaction temperature and subject to alkylation reaction to obtain a product under the condition that an acidic catalyst exists; the product is cooled by water to reduce temperature and then subjects to oil-water separation to obtain a water phase and an oil phase, wherein the water phase is purified to be recycled, the oil phase is rectified to be separated to obtain the benzene, the methylbenzene and the dimethylbenzene, and the methylbenzene and the dimethylbenzene are used as target products to separate from a reaction system; and unreacted benzene is returned to be circulated and continuously reacted together with the raw material benzene. The invention has high catalyst selectivity and can conveniently regulate the selectivity of the methylbenzene and the dimethylbenzene.

Antiperspirant emulsions which exhibit excellent phase stability even in the presence of an effective concentration of antiperspirant salts in solution and which are thickened are obtainable by dispersing a hydratable polymer and particularly an amphoteric or cationic modified starch in an aqueous emulsion forming a viscous emulsion, often at an elevated temperature, subjecting the emulsion to high shear, thereby reducing the droplet size of the dispersed oil phase, bringing the emulsion to below 40° C. and introducing the antiperspirant, preferably in aqueous solution. The viscous emulsion subjected to high shear mixing desirably has a Sheer Stress of 10 to 500 Pa. The resultant emulsions show good phase stability even when they contain aluminium/ zirconium antiperspirant salts that promote instability and even at elevated storage temperatures such as at 50° C.