14 results about "Magnetic polymer" patented technology

The invention relates to the field of biological detection, in particular to microspheres and a preparation method and application thereof. The invention provides a preparation method of magnetic polymer microspheres. The preparation method comprises the following steps: S1, obtaining magnetic microspheres with carboxyl groups; s2, activating the magnetic microspheres with carboxyl in the step S1 to obtain activated magnetic microspheres; s3, mixing the activated magnetic microspheres obtained in S2 with a first compound and a second compound, reacting, and collecting the microspheres to obtain the magnetic polymer microspheres, the first compound and the second compound competitively react with the carboxyl of the activated magnetic microspheres. The preparation method provided by the invention is simple and convenient to operate, mild in condition and good in repeatability, and the prepared microspheres are accurate and controllable in carboxyl density and uniform in distribution, have the advantages of high magnetic responsiveness, good dispersity, dispersion stability, good biocompatibility and the like, and can be widely applied to the fields of biological separation, diagnosis and the like.

The invention relates to a magnetic polymer microsphere and a preparation method and application thereof.The magnetic polymer microsphere comprises a nano Fe3O4 particle magnetic core and a polymer shell layer, the polymer shell layer internally comprises the nano Fe3O4 particle magnetic cores which are independently dispersed, the polymer shell layer comprises a porous copolymer framework containing sulfonic acid groups, and the porous copolymer framework is a porous copolymer framework containing the sulfonic acid groups. The sulfonic acid group is grafted on the surface of the porous copolymer framework. The magnetic polymer microspheres provided by the invention are uniform in particle size, and can meet the requirements of structure regulation and application performance. Wherein the magnetic cores of the nano Fe3O4 particles are independently and uniformly dispersed in the polymer shell layer to form the multi-core magnetic polymer microspheres, so that an external magnetic field can be responded more efficiently, the magnetic responsiveness is strong, and the magnetization intensity is uniform; sulfonic acid groups grafted on the surface of the porous copolymer skeleton can significantly improve the adsorption capacity of the magnetic polymer microspheres to rare earth ions, can realize rapid magnetic response recovery of the rare earth ions, and have the advantages of large adsorption capacity, greenness, no pollution and the like.

The invention discloses a method for producing medium-chain fatty acid through a core-shell structure magnetic polymer material reinforced biological carbon chain lengthening reaction, which comprises the following steps: by taking a perishable organic solid waste as a raw material, adding core-shell structure magnetic polypyrrole, adding a culture medium solution containing a substrate, adding a domesticated inoculum, and carrying out a reaction for 2-3 hours; a fermentation system for producing hexanoic acid through biological carbon chain lengthening is constructed for reaction, the reaction temperature is 30-40 DEG C, and the pH value is weak acidity; according to the magnetic polypyrrole with the core-shell structure, ferroferric oxide is used as a core, and polypyrrole is used as a shell; the problems that single magnetic particles are agglomerated, magnetic components are prone to loss, and traditional materials are difficult to recycle and large in adding amount are solved, and the performance stability and the reaction promoting capacity are enhanced by means of the structural advantages of the materials. Meanwhile, the efficiency of the carbon chain lengthening reaction and the yield of medium-chain fatty acid are remarkably improved, and high-valued conversion of the perishable organic solid waste is achieved.

This invention belongs to the field of human-computer interaction technology and discloses a self-powered human-computer interaction sensing glove based on 3D printing and its printing method. The sensing glove includes a flexible substrate layer, conductive coils, and a magnetic polymer layer. The flexible substrate layer is a wearable flexible substrate glove integrally formed by 3D printing. The magnetic polymer layer is formed by 3D printing in the thumb area of ​​the flexible substrate glove. The conductive coils are formed by 3D printing in the other finger areas of the flexible substrate glove. During operation, the magnetic polymer layer in the thumb area moves relative to the conductive coils in the other finger areas, causing a change in the magnetic flux through the conductive coils, thereby generating characteristic electrical signals. This invention can generate characteristic electrical signals through the relative movement of the conductive coils and the magnetic polymer, and wirelessly transmit these characteristic electrical signals to an external terminal device, enabling gesture recognition and human-computer interaction even in non-visual environments.

The invention belongs to the field of preparation of hydroxybutyl acrylate by a continuous rectification device, and particularly relates to a hydrophobic mesoporous confinement type Sn < 2 + >-SO3H double-acid-site magnetic polymer solid acid catalyst as well as a preparation method and application of the hydrophobic mesoporous confinement type Sn < 2 + >-SO3H double-acid-site magnetic polymer solid acid catalyst. The invention synthesizes a hydrophobic mesoporous confinement type Sn < 2 + >-SO3H double-acid-site magnetic polymer solid acid catalyst Fe3O4 (at) mP (St-FD-Sn)-SO3H, the catalyst integrates two different catalytic active centers (Sn with Lewis acidity and-SO3H with Bronsted acidity), the catalyst has a better catalytic effect, and the ester exchange reaction can reach a higher yield. Compared with the traditional purification method that rectification purification is carried out after continuous extraction, the method adopting continuous rectification for product purification has the advantages that the introduction of an extracting agent is reduced, the product is purer in quality and higher in yield, and the production cost is obviously reduced.

The invention discloses an optical fiber cantilever magnetic field sensing probe based on magnetic polymer microspheres and a preparation method thereof. The optical fiber cantilever magnetic field sensing probe comprises an optical fiber body and an optical fiber cantilever fixed to one end face of the optical fiber body. The optical fiber cantilever is cylindrical, and the tail end face of the optical fiber cantilever is wrapped with a magnetic polymer microsphere. According to the optical fiber cantilever magnetic field sensing probe, the cylindrical optical fiber cantilever is formed on one end face of the optical fiber body, and the magnetic polymer microsphere wraps the tail end face of the optical fiber cantilever, so that when the obtained optical fiber cantilever magnetic field sensing probe is used for detecting an environment magnetic field, excellent magnetic field response characteristics can be obtained, and meanwhile, the manufacturing process is simple.

The application relates to the technical field of biotechnology, and discloses a synthesis and functional modification technology of large-diameter core-shell type magnetic polymer microspheres, which comprises the following steps: S1, preparation and modification of polymer microspheres; S2, adsorption of magnetic fluid on the surface of the polymer microspheres; S3, surface cross-linking and functionalization of the magnetic microspheres; S4, multilayer adsorption of the magnetic fluid on the surface of the polymer microspheres; and S5, functionalization and application. The synthesis and functional modification technology of the large-diameter core-shell type magnetic polymer microspheres fills the short board of the prior art, and can amplify the preparation process of the uniform and large-diameter magnetic polymer microspheres for large-scale production. The particle size and uniformity of the core-shell type magnetic polymer microspheres depend on the size and uniformity of the polymer microsphere core, and the polymer microsphere core can have a relatively wide particle size range, and polymer microspheres with a particle size of several hundred nanometers to millimeters can be implemented through the technical scheme.

The invention discloses a magnetic ion imprinted polymer as well as a preparation method and application thereof. The preparation method of the magnetic ion imprinted polymer comprises the following steps: 1) dispersing a functional monomer and template molecules in a solvent for pre-assembly to obtain a complex solution; 2) dispersing the oleic acid-coated modified Fe3O4 particles, a cross-linking agent and an initiator by using a solvent, and then adding into the complex solution for polymerization reaction to obtain a magnetic polymer; and 3) washing the magnetic polymer with an eluent to obtain the magnetic ion imprinted polymer. The magnetic ion imprinted polymer can specifically recognize and adsorb Sb oxygen-containing anions, is easy to separate from wastewater, is easy to regenerate, can be used for efficiently recovering and recycling antimony in antimony-containing wastewater, and is simple in preparation method, easy in raw material obtaining, low in production cost and suitable for large-scale industrial production and application.

The application discloses a kind of multistage rigid-flexible heterostructure crosslinking magnetic polymer microspheres and its preparation method and application.The microsphere is the continuum of global chemical crosslinking, and its microstructure is composed of five parts of high-density rigid skeleton unit, flexible accommodation matrix unit, rigid-flexible transition interface unit, magnetic functional component and organic-inorganic hybrid interface layer.The application uses the strategy of step-by-step assembly-in-situ mineralization, uses RAFT active polymerization and starvation feeding process to construct nonlinear crosslinking density gradient network, and realizes the topological interlocking of magnetic component and polymer matrix by in-situ induction of metal chelating monomer to limit the growth of rare earth doped ferrite nanocrystal cluster.The application fundamentally eliminates the shell peeling risk caused by physical interface, realizes the zero leakage of magnetic component.The microsphere has the advantages of fast magnetic response speed, high structural stability and rich surface biological activity sites, and has important application prospect in the field of liquid phase biochip and in-vitro diagnostic reagent.

The application discloses an anisotropic three-dimensional polymer with magnetic driving form adaptability and a preparation method and application thereof. The three-dimensional polymer network is embedded with pre-prepared magnetic microfibers with high length-diameter ratio and anisotropic characteristics. Under the action of a dynamic external magnetic field such as an alternating or rotating magnetic field, the internal magnetic microfiber network can generate high-efficiency mechanical torque and anisotropic driving force, and endow the macroscopic polymer with extremely sensitive motion deformation capability and local mechanical force output. The application breaks the mechanical isotropy limitation caused by the random dispersion of nanoparticles in traditional magnetic polymers, and can prepare macroscopic gel patches, injectable microfluidic microspheres and flexible elastomers across scales, and has extremely high commercial and scientific research conversion value in the fields of micro-nano soft robot driving, biomimetic dynamic tissue engineering scaffolds, cell mechanical culture matrix and intelligent drug delivery carriers.

The invention relates to a preparation method and application of carboxyl magnetic microspheres, and the preparation method comprises the following steps: (1) coating a polymer layer: carrying out polymerization reaction on magnetic polymer microspheres, a first initiator, a polymeric monomer, a carboxylic acid monomer and a cross-linking agent to obtain the magnetic microspheres coated with the polymer layer; and (2) carboxyl group derivation: carrying out amination reaction on the magnetic microspheres coated with the polymer layer obtained in the step (1) and an amination reagent, and then carrying out carboxyl derivation reaction with an anhydride compound to obtain the carboxyl magnetic microspheres. The carboxyl magnetic microspheres prepared by the preparation method provided by the invention have the advantages of high carboxyl content, high stability, uniform size and the like, and have wide application prospects in biological medicines.

The invention provides a steel bridge deck pavement method based on a magnetic force effect, which comprises the following three steps of: paving a magnetic response epoxy anti-sliding waterproof bonding layer on a steel bridge deck, then paving a magnetic epoxy resin asphalt concrete layer, and finally paving an asphalt mastic macadam mixture layer. The magnetic response epoxy anti-sliding waterproof bonding layer adopts the magnetic response epoxy adhesive cement and the aggregate to form an adhesive cement-aggregate-adhesive cement sandwich structure, and the strength and the shearing strength of the bonding layer are enhanced by means of the magnetic adsorption effect between the magnetic polymer microspheres and the magnetic blocks. The magnetic epoxy resin asphalt concrete layer also generates interlayer magnetic adsorption with the'adhesive cement-aggregate-adhesive cement 'sandwich structure through internal magnetic polymer microsphere-magnetic blocks, and the magnetic epoxy resin asphalt concrete layer and the'adhesive cement-aggregate-adhesive cement' sandwich structure jointly form a'double-magnetic effect functional layer 'and are tightly connected through the magnetic adsorption effect, so that the overall cohesiveness and anti-sliding performance of the pavement system are effectively enhanced, and the pavement system is suitable for being used in the field of pavement. The durability and the service life of the steel bridge deck pavement can be improved, and the driving safety is guaranteed.

The invention belongs to the technical field of biomedical detection, and provides a prostatic cancer olaparione response marker determination system and a determination method and application thereof. A multifunctional polymer brush is grafted on the surface of a core-shell magnetic polymer microsphere, an HRR gene oligonucleotide probe is coupled through carbodiimide-mediated amidation reaction, and efficient enrichment and accurate quantitative detection of ultralow-abundance mutant alleles are achieved by combining a digital PCR technology. The use amount of the magnetic oligonucleotide probe in a single 20L reaction system is 0.5-200g, and the positive detection rate of HRR gene mutation sites with allele frequency of 0.10%-0.50% is not less than 95%. The problems that in the prior art, low-abundance target capturing efficiency is low, non-specific adsorption is high, and digital PCR quantitative accuracy is poor are solved, a high-sensitivity and high-specificity molecular diagnosis tool is provided for olapara utilization drug decision-making of castration-resistant metastatic prostate cancer patients, and wide clinical application value is achieved.

The invention discloses an adsorption material for sewage treatment and a preparation method thereof, and belongs to the technical field of sewage treatment.The preparation method comprises the steps that sodium bentonite is dispersed through sodium hexametaphosphate, acrylic acid is neutralized and then subjected to a copolymerization reaction with sodium methallyl sulfonate in the presence of a cross-linking agent, and polymer modified bentonite is obtained; ferroferric oxide magnetic particles are loaded on polymer modified bentonite through ferric salt coprecipitation, lanthanum ions are used for surface complexing modification to obtain magnetic polymer modified montmorillonite, alkali lignin is sulfonated and then subjected to graft copolymerization with N-vinyl pyrrolidone, and defluorination type dispersing agent powder is obtained. And then physically mixing with the magnetic polymer modified montmorillonite, so that the obtained adsorbing material is high in magnetic separation recovery rate and beneficial to stable fluorine removal of sewage.