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179 results about "Nanocapsules" patented technology

A nanocapsule is a nanoscale shell made from a nontoxic polymer. They are vesicular systems made of a polymeric membrane which encapsulates an inner liquid core at the nanoscale. Nanocapsules have many uses, including promising medical applications for drug delivery, food enhancement, nutraceuticals, and for self-healing materials. The benefits of encapsulation methods are for protection of these substances to protect in the adverse environment, for controlled release, and for precision targeting. Nanocapsules can potentially be used as MRI-guided nanorobots or nanobots, although challenges remain.

Method for repairing soil heavy metal pollution by coupling soybean urease with biochar cementing agent

The invention discloses a method for restoring soil heavy metal pollution by coupling soybean urease with a charcoal cementing agent, and relates to the technical field of soil heavy metal pollution restoration, and the method comprises the following steps: dynamic microbiome regulation and control: introducing photosensitive protein into soil functional bacteria; the acyl homoserine lactone analogue is synthesized and applied to soil, and is competitively combined with a microbial quorum sensing receptor to block an inhibitor to secrete a signal channel; according to the method, microbial urease secretion is regulated and controlled through optogenetics, an inhibitor signal is blocked through quorum sensing interference, and a microbiome is precisely regulated and controlled; the pH-responsive nanocapsule releases an inhibitor in a targeted manner, and the magnetic-responsive nanochain dynamically captures interfering bacteria, so that the limitation of passive adsorption is broken through; the gene editing plant releases coumarin to inhibit fungal metabolism, and the engineering mycorrhizal fungi physically shields an inhibitor to construct cross-biosphere cooperative defense; the urease activity and the heavy metal removal rate are remarkably improved, meanwhile, the soil microbial diversity is maintained, and the soil specificity interference problem is solved.
Owner:GUANGDONG OCEAN UNIVERSITY

Preparation method and application of ceramic glaze layer protecting and repairing material

PendingCN121537228ACoatingsCrazingPolypropylene
The invention discloses a preparation method and application of a ceramic glaze layer protecting and repairing material, and belongs to the technical field of cultural relic protection. The preparation method comprises preparation of a core-shell self-repairing nanocapsule, and the preparation of the core-shell self-repairing nanocapsule comprises the following steps: reacting a calcium chloride solution with a sodium hydroxide solution, then adding sodium polyacrylate and nano ZnO, and carrying out dispersion, centrifugation, washing and other operations to prepare the nano Ca (OH) 2-ZnO composite material. The nano Ca (OH) 2-ZnO composite material of the core-shell self-repairing nanocapsule can be rapidly released through the 3.5 nm aperture of the mesoporous SiO2 shell, glaze layer cracks are physically filled and react with CO2 in air to generate CaCO3 crystals, crack plugging is achieved, meanwhile, dynamic disulfide bonds of a PU layer are broken and recombined under stress stimulation, a crack interface is repaired through chemical bonding, and the performance of the core-shell self-repairing nanocapsule is improved. The 24-hour crack repair rate is greater than or equal to 96%, and the limitation of'one-time repair 'of a traditional material is solved.
Owner:XIAN UNVERSITY OF ARTS & SCI

Chitosan nanocapsule as well as preparation method and application thereof

PendingCN120420904AFibre treatmentMicroballoon preparationCrosslinked chitosanSodium phosphates
The invention relates to the technical field of functional materials, in particular to a chitosan nanocapsule as well as a preparation method and application thereof. The preparation method of the chitosan nanocapsule comprises the following steps: (a) mixing and emulsifying a chitosan solution, an oil-in-water emulsifier and essential oil to form an oil-in-water emulsion, adding an aqueous solution of sodium tripolyphosphate into the oil-in-water emulsion, and stirring to obtain a first mixture; (b) adding the first mixture into an oil phase solvent containing a water-in-oil emulsifier, and stirring to obtain a multiple emulsion; and (c) adding an aqueous solution of a dialdehyde cross-linking agent into the multiple emulsion, carrying out a cross-linking reaction, collecting a solid-phase substance, and drying. The physical / chemical double-crosslinking chitosan nanocapsule is obtained by utilizing physical crosslinking between the chitosan and the sodium tripolyphosphate and chemical crosslinking between the chitosan and the binary aldehyde crosslinking agent, so that the encapsulation efficiency and the encapsulation efficiency of the nanocapsule are remarkably improved; meanwhile, the nanocapsule also has pH responsiveness and has a slow release effect after pH response.
Owner:DONGHUA UNIV +1

A drug carrier system and production method thereof

The present invention relates to a drug carrier system in the form of nanocapsules and nanospheres loaded with luteolin and oleuropein, which have a counteracting effect on tumour cell growth, invasion and angiogenesis, and to a production method (100) of this drug carrier system.
Owner:HACETTEPE UNIVERSITESI REKTORLUK +1

Buffer solution supporting multiple fluorescent quantitative PCR (Polymerase Chain Reaction) and preparation method thereof

The invention relates to a buffer solution supporting multiple fluorescent quantitative PCR and a preparation method thereof, and relates to the technical field of biochemical reagents, the buffer solution comprises Tris-HCl, (NH4) 2SO4, KCl, a temperature control type magnesium ion nanocapsule and an additive; the additive is prepared from polyethylene glycol, betaine, trehalose, tetramethylammonium chloride and acetylated BSA (Bovine Serum Albumin); the temperature control type magnesium ion nanocapsule is of a core-shell structure, the core comprises MgCl2 accounting for 1-5 mM of the concentration of the buffer solution, pyrophosphatase accounting for 0.1-0.5 U / mu L, phospholipid accounting for 10-30 mg / mL, cholesterol accounting for 5-15 mg / mL and an inorganic solution, and the shell comprises a temperature-sensitive polymer accounting for 20-45 wt% of the concentration of the buffer solution. The buffer solution can dynamically adjust the concentration of Mg < 2 + >, and the situation that the amplification efficiency is affected due to the fact that the concentration of Mg < 2 + > is difficult to adjust is avoided.
Owner:SHANDONG JIANMICROORGANISM TECH CO LTD

Magnesium oxide board capable of releasing negative oxygen ions for long time

The invention provides a magnesium oxide board capable of releasing negative oxygen ions for a long time and a preparation method of the magnesium oxide board, and relates to the technical field of building materials, the magnesium oxide board comprises a magnesium oxide board base material and nano microcapsules uniformly dispersed in the magnesium oxide board base material, the core of each nano microcapsule is high-activity negative ion powder, the high-activity negative ion powder is coated with SiO2, and the core of each nano microcapsule is coated with SiO2. A shell of the nano microcapsule is made of a humidity response material containing a photocatalytic material. According to the negative oxygen ion long-acting release technology based on combination of light-humidity double-response collaborative triggering and the nano microcapsules, the technical problems that traditional negative oxygen ion material release depends on a single environment condition, and release is uncontrollable due to direct exposure of the negative oxygen ion material are solved, intelligent on-demand release of negative oxygen ions is achieved, and the service life is remarkably prolonged.
Owner:QINGDAO BEIYUAN ENVIRONMENTAL PROTECTION BUILDING MATERIALS CO LTD +1

Coal mine tunnel roof displacement monitoring device

The invention discloses a coal mine tunnel roof displacement monitoring device, and belongs to the technical field of tunnel roof displacement monitoring, grooves are etched in the outer surface of an anchor rod body through an ultrafast laser micro-nano machining technology, the grooves are spirally distributed, graphene sensing fibers and flexible optical fiber spiral layers are embedded in the grooves, and the graphene sensing fibers and the flexible optical fiber spiral layers are arranged on the outer surface of the anchor rod body. The graphene sensing fiber and the flexible optical fiber spiral layer are used for monitoring the wide area of stress distribution on the surface of the anchor rod body, and the outer surface of the anchor rod body is coated with a nanocapsule filling type self-repairing coating. And the nanocapsule in the nanocapsule filling type self-repairing coating is broken to release the silane repairing agent to repair the crack surface. The spiral groove is etched in the anchor rod body, and the graphene sensing fiber and the flexible optical fiber spiral layer are embedded, so that the stress distribution and stress change of the surface of the anchor rod body can be monitored in a wide area, accurate data are provided for top plate displacement monitoring, and the monitoring accuracy and continuity are improved.
Owner:HUAIBEI MINING CO LTD

Multicomponent nanocapsules for enhanced oil recovery

A multicomponent nanocapsule composition comprising a core particle, an oil phase encapsulating the core particle, and an aqueous phase in which the encapsulated core particle is suspended is provided. The porous particle includes a cationic surfactant encapsulated in a porous particle. The oil phase includes an anionic surfactant and a zwitterionic surfactant. A method of making a multicomponent nanocapsule composition is also provided. A method of treating a hydrocarbon-bearing formation with the multicomponent nanocapsule composition is provided. The method may include providing a multicomponent nanocapsule composition, introducing the multicomponent nanocapsule composition into the hydrocarbon-bearing formation, displacing hydrocarbons from the hydrocarbon-bearing formation by contacting the multicomponent nanocapsule composition with the hydrocarbons, and recovering the hydrocarbons.
Owner:SAUDI ARABIAN OIL CO

Biodegradable hydraulic oil composition and preparation method of hydraulic oil

PendingCN121991749AImprove Oxidation Stabilitypromote degradationBase-materialsDemulsifierFiltration
The invention relates to a biodegradable hydraulic oil composition and a preparation method of hydraulic oil, and relates to the technical field of hydraulic oil compositions.The hydraulic oil composition comprises, by weight, 20-37% of ester oil, 5-10% of refined vegetable oil and 5-10% of a demulsifier, and the total weight of the ester oil, the refined vegetable oil and the demulsifier is 100%. The content of the refined vegetable oil is 62-79.9 wt%, the content of the demulsifier is 0.1-1 wt%, and the preparation method of the refined vegetable oil comprises the following steps: pre-loading a nanocapsule with an antioxidant as an inner core in activated clay, loading the activated clay pre-loaded with the nanocapsule into deacidified oil, and filtering to obtain the refined vegetable oil. The hydraulic oil composition disclosed by the invention has excellent biodegradability and also has the technical effects of relatively good oxidation stability and viscosity-temperature property.
Owner:HUBEI BODA SPECIAL LUBRICANT CO LTD

Mildew-proof and moth-proof polyurethane polystyrene foam manufacturing process

The invention relates to a mould-proof and mothproof polyurethane foaming adhesive manufacturing process which comprises the steps of prepolymer preparation, prepolymer mixture preparation, foaming agent mixture preparation, foaming forming, curing and finishing. According to the mould-proof and mothproof polyurethane foaming adhesive manufacturing process, a mould-proof agent is packaged in a silicon dioxide nanocapsule, so that the dispersity and the slow-release effect are improved; the pressure of the mixing head of the high-pressure foaming machine is increased to 20 MPa, the micron-sized dispersion effect is ensured, microwave radiation is adopted to replace a conventional curing mode, the working efficiency is improved, and the scientificity and practical value of the whole process are improved.
Owner:HEBEI RONGRUNDA BUILDING MATERIALS TECH CO LTD

Traditional Chinese medicine aromatic penetration enhancer containing plant cell extract and preparation method of traditional Chinese medicine aromatic penetration enhancer

The invention discloses a plant cell extract-containing traditional Chinese medicine aromatic penetration enhancer and a preparation method thereof, and the penetration enhancer comprises the following components in parts by mass: 8-15 parts of storax nano-vesicles, 3-8 parts of agilawood nano-vesicles, 1-5 parts of refined turpentine, 0.5-3 parts of panax notoginseng saponins, 0.5-3 parts of rhododendron dauricum oil and 20-35 parts of grape seed oil, the storax nano-vesicles and the agilawood nano-vesicles are exosome-like nano-vesicles extracted from plant secretion, and the particle size of the vesicles is 50-200 nm. Skin interstices are opened, skin meridians and blood are dredged, and accordingly relieving, inflammation resisting, redness improving and skin barrier repairing are achieved.
Owner:GUANGZHOU LUGUO FANGHUA BIOTECHNOLOGY CO LTD

Composition for fertilization and treating trees, shrubs and climbing plants with programmed release of the active substance that at the injection location induces formation of a clump of young roots that become the mouth of the tree

ActiveUS12342816B2BiocideContainer decorationsFungicideCapsule
The disclosed composition for fertilization and treating trees, shrubs and climbing plants with programmed release of the active substance is comprising the active substance stored in capsules made by nanoencapsulation or microencapsulation method and wherein based on capsule membrane the time of release of the active substance is adjusted. The active component stored in the nanocapsules or microcapsules can be such that it acidifies the surrounding soil in the range of pH 2.5 to pH 6.5. One example of such active component is the use of citric acid, which is completely ecological and does not create environmental pollution. Also, the active component in the nanocapsules can be such that it regulates the acidity of the soil in the range of pH 6.5 to pH 7.0. Furthermore, the active component in the special capsules can be an insecticide and / or in the special capsules fungicide, and / or in the special capsules acaricide and / or in the special capsules pheromone and / or in the special capsules repellent.
Owner:HERBAFARM MAGNOLIJA D O O

Preparation Method and Application of Pesticide Nanocapsule Controlled Release Agent

The present invention belongs to the field of pesticide formulations, and particularly relates to a preparation method and application of a pesticide nano-capsule controlled release agent, which comprises the following steps: adding a n-butanol solution containing a pesticide active ingredient into an aqueous solution containing a surfactant, stirring evenly to form an oil-in-water pesticide microemulsion; adding an aqueous tannic acid solution and an aqueous FeCl3 solution into the obtained product, so that Fe 3+ and the coordination polymer formed by the coordination of tannic acid are wrapped on the surface of the droplets of the oil-in-water pesticide microemulsion, and then through centrifugation, separation, washing and drying, the target product, the pesticide nano-capsule controlled release agent, is obtained. The present invention also discloses a method for controlling the release of pesticides in response to 8 stimuli, including acidity, alkalinity, glutathione, vitamin C, hydrogen peroxide, phosphate, phytic acid, sunlight (temperature). The present invention has the characteristics of simple preparation method, less use of raw materials, low cost, high pesticide loading rate, and easy degradation of nano-capsules.
Owner:NANJING UNIV

A pH-responsive Mat@CS-Pro nanocapsule antifouling agent and its preparation method and application

The present invention discloses a pH-responsive Mat@CS-Pro nanocapsule antifouling agent, its preparation method, and application, belonging to the technical field of marine antibacterial antifouling and nanocomposite materials. The invention comprises the following steps: dissolving matrine in anhydrous ethanol containing lecithin to prepare an oil phase; dissolving chitosan in anhydrous acetic acid to prepare an aqueous phase; preparing Mat@CS oil / water microcapsules by a microemulsion method; and preparing an aqueous solution of the prepared Mat@CS oil / water microcapsules and D-Proline. The solution is stirred in an ice-water bath, filtered through a dialysis bag in a deionized water solution, and freeze-dried to obtain the pH-responsive Mat@CS-Pro nanocapsule antifouling agent. The material disclosed is environmentally friendly and has excellent antibacterial properties, providing insights into the exploration of intelligent pH-responsive antifouling agents in the marine field.
Owner:UNIV OF SCI & TECH BEIJING

Biocidal infused composite fabric for cabin interiors

A biocidal composite wall or surface fabric installable within an aircraft cabin or other vehicle interior space includes a flexible woven layer. The woven layer is treated on its outer surface with a biocidal polymer coating. For example, the polymer coating may incorporate biocidal microcapsules or nanocapsules configured for controlled release of biocidal compounds in response to physical contact or other stimuli. The released biocidal compounds compromise or kill microbial compounds deposited on the outer surface, e.g., via physical contact by passengers or crewmembers. The woven layer includes additional biocidal molecules incorporated into its fibers and strands, the biocidal molecules capable of biocidal action in response to contact with the fabric.
Owner:BE AEROSPACE INC

Preparation method of peppermint essence

The invention relates to a preparation method of peppermint essence, which solves the problems of quick volatilization and poor durability of the traditional peppermint essence by optimizing the combination of essence components and a slow-release carrier by adopting a multi-layer microcapsule slow-release technology and a nanocapsule technology. According to the method, essence components such as menthol, menthone and leaf isovalerate are mixed with at least two layers of microcapsules, the outer layer microcapsules slowly release fragrance, the inner layer microcapsules quickly release fragrance, and it is ensured that the fragrance is kept for a long time in the using process. Meanwhile, the essence is uniformly dispersed in different carrier systems through ultrasonic-assisted emulsification by adopting a nanocapsule technology, so that the stability and dispersity of the essence are improved. In addition, the temperature-responsive and pH-responsive polymer materials are introduced, so that the release rate of the essence can be adjusted according to the external environment, and the adaptability of the essence is further enhanced.
Owner:GUANGZHOU ZHENXIN FLAVORS & FRAGRANCES CO LTD

Preparation method of photoresponse type UV regulation and control material and 3A optical film

The invention discloses a preparation method of a light response type UV regulation and control material and a 3A optical film, and relates to the technical field of optical films.The preparation method comprises the steps that spiropyrane is dissolved in ethyl acetate to form an oil phase, and first liquid is obtained; dispersing nano silicon dioxide in a water phase containing gelatin to obtain a second liquid; stirring and mixing the first liquid and the second liquid to form an emulsion; evaporating the emulsion at 55-65 DEG C for at least 12 hours to form a spiropyrane-silicon dioxide hybrid nanocapsule; the spiropyrane-silicon dioxide hybrid nanocapsule is dispersed into light-cured polyacrylate, and a light response type UV regulation and control material is obtained; the 3A optical film comprises a light response type UV regulation and control layer, and the material of the light response type UV regulation and control layer is a light response type UV regulation and control material. The 3A optical film realizes flexible regulation and control of absorption of ultraviolet rays according to different weather scenes.
Owner:YUEDA OPTRONICS TECH(ZHEJIANG) CO LTD

Nanocapsules for delivery of cell modulating agents

The present disclosure relates to a polymer nanocapsule comprising a ribonucleoprotein complex and a method for its delivery.In some embodiments, the polymer nanocapsule comprises a polymer shell and a ribonucleoprotein complex, wherein the polymer shell comprises at least one positively charged monomer, at least one neutral monomer, and a crosslinker.Also disclosed is a conjugate of the polymer nanocapsule linked to one or more targeting moieties and / or one or more stabilizing moieties.
Owner:CENTEON A LLC OF DELAWARE

Display apparatus and electronic apparatus including the display apparatus

Provided is a display apparatus including a display panel, an optically clear adhesive (OCA) over the display panel, and an auxiliary layer between the display panel and the OCA and including a nanocapsule and an OCA composition, wherein the nanocapsule is a gas-generating particle and has a diameter of at least about 100 nm and not more than about 2 μm.
Owner:SAMSUNG DISPLAY CO LTD +1

Biofilm carrier suitable for low-temperature sewage treatment, preparation method and application

The invention discloses a biofilm carrier suitable for low-temperature sewage treatment and a preparation method and application thereof.The biofilm carrier takes SiC ceramic as a biofilm framework, the upper portion of the SiC ceramic is coated with a photo-thermal agent to form a photo-thermal conversion functional area, the lower portion of the SiC ceramic is a microbial adhesion functional area, and meanwhile the upper portion of the SiC ceramic is loaded with temperature response type nanocapsules; and efficient photo-thermal conversion can be carried out, functional bacteria are adsorbed and enriched, the biomass is improved, and the bacterial activity is improved in a low-temperature environment. The preparation method of the biofilm carrier is simple, and the ammonia nitrogen removal rate is high after the biofilm carrier is applied to microbial wastewater treatment.
Owner:PEKING UNIV

Self healing plasma electroytic oxidation coating

PendingUS20260117394A1Anti-corrosive paintsPlasma electrolytic oxidationElectrolysis
An aircraft component including an aluminum substrate and a plasma electrolytic oxidation (PEO) coating disposed on the aluminum substrate. The PEO coating includes a plurality of cavities. A set of nano capsules disposed in the plurality of cavities, with at least a portion of the nano capsules in the set of nano capsules containing a corrosion inhibitor.
Owner:HAMILTON SUNDSTRAND CORP

A method for synthesizing catalase nanocapsules based on gas-liquid two-phase flow microfluidic technology and application

The application discloses a method for synthesizing catalase nanocapsules based on gas-liquid two-phase flow microfluidic technology and application. Nitrogen is used as a gas phase, and a liquid phase containing acrylated catalase, a monomer mixture and a crosslinking agent is used to form Taylor flow in a microfluidic chip. The internal vortex of the gas-liquid interface is used to enhance the mixing efficiency, and in-situ radical polymerization on the surface of the enzyme is realized. By screening six microfluidic chips with different structures, the geometric parameters of the chip and the hydrodynamic conditions are optimized, and the particle size uniformity and enzyme activity retention rate of the nanocapsules are significantly improved. The application also discloses a continuous flow reactor system for loading the obtained nanocapsules on macroporous resin microspheres to construct a continuous flow reactor system, and the system is used for efficient degradation of hydrogen peroxide in semiconductor wastewater. The method has the advantages of high mixing efficiency, mild reaction conditions, continuous production and the like, the obtained nanocapsules have the advantages of narrow particle size distribution, high enzyme activity and good stability, and are suitable for the field of industrial wastewater treatment.
Owner:FUZHOU UNIV

Three-signal sensor based on aptamer and pH response double-gating nanocapsule as well as preparation method and application of three-signal sensor

The invention belongs to the technical field of food safety and rapid detection, and discloses an acetamiprid residue three-signal (colorimetric, photo-thermal and fluorescent) synergistic detection method based on aptamer and pH response double-gated nanocapsules. According to the invention, UiO-66 is used as a nano container for packaging a signal molecule TMB, and an aptamer (Apt) and chitosan (CS) are assembled on the surface of UiO-66, so that the nano capsule (UiO-66 (at) TMB (at) Apt (at) CS) which has dual response to the aptamer and pH and can accurately release TMB is constructed. The method comprises the following steps: under an acidic condition, after a target object is added, CS cracking and specific binding of Apt and the target object lead to release of TMB, firstly, HRP and H2O2 are added, and then colorimetric detection is carried out; then, irradiating the solution subjected to color development by using 808 nm laser, and carrying out photo-thermal detection; finally, a proper amount of QDs is added for fluorescence detection, and three-signal detection of acetamiprid residues is achieved.
Owner:YANGZHOU UNIV

AlN / Fe-C-C nanocapsule as well as preparation method and application thereof

The invention provides a preparation method of an AlN / Fe-C-C nanocapsule, and relates to the technical field of nanomaterials, a mixed molding target material containing Fe, Al and C is taken as an anode, a graphite electrode is taken as a cathode, and arc discharge is carried out by adopting a plasma arc evaporation process in the atmosphere of catalytic gas and working gas containing nitrogen, so that the AlN / Fe-C-C nanocapsule is prepared. The preparation method comprises the following steps: adopting a mixed molding target material containing Fe, Al and C as an anode to form an AlN / Fe-C-C nanocapsule with a graphene matrix; wherein the graphene can maintain the dielectric loss capability at a high frequency band, and the AlN / Fe-C-C takes AlN and Fe-C as a core and takes a carbon shell as a shell, so that good impedance matching can be realized, and the material has the dielectric loss capability at a low frequency band, thereby solving the problem of narrow wave-absorbing frequency band of the existing nanocapsule material.
Owner:INST OF METAL RESEARCH - CHINESE ACAD OF SCI

Preparation method of light conversion adhesive film and light conversion adhesive film

The invention relates to the technical field of light conversion adhesive films, and particularly provides a preparation method of a light conversion adhesive film and the light conversion adhesive film. The invention aims to solve the problem of performance degradation caused by the fact that the potential of improving the efficiency of a polishing agent in the prior art is limited by EVA aging acid production. Therefore, the method comprises the following steps: providing a light conversion agent; and packaging the light conversion agent by using a copolymer to obtain the light conversion nanocapsule, modifying the surface of the light conversion nanocapsule by using a silane coupling agent to obtain a modified light conversion nanocapsule; providing base material particles; and mixing the modified light conversion nanocapsule, base material particles and a compatibilizer, and carrying out melt extrusion and film casting to obtain the light conversion adhesive film. The light conversion agent is packaged by using the copolymer, so that the stability of the light conversion agent can be improved. Meanwhile, the quantum dots and the organic light conversion agent are wrapped together, so that the quantum dots and the organic light conversion agent in the nanocapsule can be ensured to generate an energy transfer phenomenon instead of a long-distance secondary light conversion phenomenon when the quantum dots and the organic light conversion agent are excited by ultraviolet light.
Owner:XINJIANG CHUANGYAOHUI NEW MATERIALS CO LTD

Cellulose ester / borate / cellulose ester nanocapsule with three-dimensional network structure as well as preparation method and application of cellulose ester / borate / cellulose ester nanocapsule

The invention discloses a cellulose ester / borate / cellulose ester nanocapsule with a three-dimensional network structure as well as a preparation method and application of the cellulose ester / borate / cellulose ester nanocapsule, and belongs to the technical field of nano composite materials. The cellulose ester / borate / cellulose ester nanocapsule with a three-dimensional network structure is prepared by taking cellulose ester as a wall material and borate nanoparticles as a core material and combining the cellulose ester with the borate nanoparticles by adopting a high-pressure homogenization method and a solvent evaporation method. The composite material is composed of spheres with the size of 100-180 nm, the PDI value of a suspension of the composite material is lower than 0.15, and the water contact angle range is 125-135 degrees. The preparation method of the composite material comprises the following steps: (1) preparing borate nanoparticles; and (2) preparing the cellulose ester / borate / cellulose ester nanocapsule. The composite material provided by the invention has structural stability, has good dispersion stability when being applied to base oil as a lubricating oil additive, and can effectively improve the tribological performance of the base oil.
Owner:GUANGXI UNIV

Nanocapsule SMCPM and application thereof in preparation of medicine for treating or preventing osteosarcoma and pulmonary metastasis

The invention relates to the technical field of biological medicines, and particularly discloses a nanocapsule SMCPM and application thereof in medicines for treating or preventing osteosarcoma and pulmonary metastasis. The SMCPM is composed of a photosensitizer Ce6 carried by mesoporous silicon oxide-manganese oxide particles, an NRF2 inhibitor ML385 and an OS targeting peptide PT-7. Experiments prove that the SMCPM is high in penetrating power and strong in cell killing effect; by down-regulating NRF2 expression and reversing nuclear translocation, a biochemical inhibitory microenvironment can be effectively repaired, the tolerance of cells to active oxygen and epithelial-mesenchymal transition activated and induced by a NOTCH1 signal axis are remarkably reduced, the oxidative stress level of the cells is enhanced, and PIT-induced immunogenic cell death is promoted; the released Mn < 2 + > and double-stranded DNA can regulate and control an immunosuppressive microenvironment by activating an STING pathway in cells, thereby inhibiting the growth of osteosarcoma and preventing lung metastasis.
Owner:ZHONGNAN HOSPITAL OF WUHAN UNIV

Liquid crystal nanocapsules and capsule solutions, optical films, optical devices, transmittance variable devices using the same

This invention relates to liquid crystal nanocapsules and capsule solutions, optical films, optical devices, and transmissivity devices using the same, wherein the liquid crystal nanocapsules comprise: a core containing liquid crystal; and a polymer shell formed on the surface of the core; wherein the sum of the initial temperature change value according to Formula 1 and the peak temperature change value according to Formula 2 is 37.5°C or less.
Owner:LG CHEM LTD