Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

7 results about "Half-life" patented technology

Half-life (symbol t1⁄2) is the time required for a quantity to reduce to half of its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo, or how long stable atoms survive, radioactive decay. The term is also used more generally to characterize any type of exponential or non-exponential decay. For example, the medical sciences refer to the biological half-life of drugs and other chemicals in the human body. The converse of half-life is doubling time.

Half-life period demonstration device and demonstration method

The invention relates to the technical field of science popularization demonstration, in particular to a half-life period demonstration device and a half-life period demonstration method. The device comprises a base body, a plurality of vertically-arranged demonstration cavities are formed in the table top of the base body, magnetic jumping blocks are arranged in the demonstration cavities, the visual states of the top faces and the bottom faces of the magnetic jumping blocks are different, and the magnetic pole directions of the top faces and the bottom faces of the magnetic jumping blocks are opposite; an electromagnet is arranged under each magnetic jumping block, all the electromagnets can be controlled by a controller to switch the magnetic pole direction, and when the controller controls part of the electromagnets to switch the magnetic pole direction, the part of the electromagnets and the bottom faces of the magnetic jumping blocks are magnetically repelled to drive the magnetic jumping blocks to jump and turn over. Therefore, radioactive decay of part of atomic nucleuses in the elements is demonstrated. According to the invention, by combining the action of a mechanical structure, the nuclear decay process and rule can be dynamically and visually displayed, so that the double problems of non-visual teaching and weak science popularization display can be solved.
Owner:HEFEI PANSHI AUTOMATION TECH

Method of determining half-life of a biomolecule of interest and kit

The present invention relates to a method of determining the half-life T1 / 2 of a biomolecule of interest, said method comprising: (a) bringing said biomolecule into contact with a compound that decreases the amount of said biomolecule; (b) determining the amount of said biomolecule as a function of time; (c) determining, from amount as a function of time, (i) the half-life T1 / 2* of said biomolecule upon said bringing into contact; and (ii) the ratio r of the equilibrium amount of said biomolecule in the presence of said compound over the equilibrium amount of said biomolecule in absence of said compound; and (d) determining said half-life as T1 / 2 = T1 / 2* / r.
Owner:BOEHRINGER INGELHEIM INT GMBH

A method and apparatus for identifying a nuclide

The application provides a nuclide identification method and device, comprising: obtaining gamma spectrum data of a target radioactive source; determining whether other characteristic peaks except for specified characteristic peaks are contained in characteristic peaks of the gamma spectrum data; if yes, determining a first peak area corresponding to the other characteristic peaks and a second peak area of the specified characteristic peaks according to the gamma spectrum data; determining a total area of the specified characteristic peaks contributed by all nuclides of the target radioactive source according to the first peak area and a peak branch ratio of each first nuclide; determining whether the second nuclide having only the specified energy peak value is contained in the target radioactive source according to the second peak area and the total area; if yes, determining the second nuclide in the target radioactive source through half-life measurement; and determining the nuclide composition of the target radioactive source according to the first nuclide and the second nuclide. The method can identify the heavy peak by setting the verification condition, and then determine the nuclide composition, so that the technical problem of nuclide missing identification can be relieved.
Owner:SHANGHAI SIM-MAX TECH CO LTD Y

Method and system for separating and preparing high-purity terbium 149 based on electromagnetic mass spectrum tandem separation technology

The invention relates to the technical field of radioactive isotope preparation, and discloses a high-purity terbium-149 separation preparation method and system based on an electromagnetic mass spectrometry tandem separation technology, and the method comprises the following steps: bombarding a 151Eu target material based on an alpha beam to obtain an irradiated target material of the 151Eu target material, and carrying out high-temperature gasification on the irradiated target material to obtain the high-purity terbium-149. The method comprises the following steps: irradiating a target material to obtain nuclide steam of the irradiated target material, carrying out strong electromagnetic separation on isobaric elements of the nuclide steam to obtain a crude separation target product of the nuclide steam, and carrying out fine separation on the crude separation target product based on a pre-calibrated high-resolution mass spectrometer to obtain terbium-149 ions of the irradiated target material. Condensing and collecting the terbium-149 ions, and dissolving the terbium-149 ions into a medical-grade terbium chloride solution of the terbium-149 ions; according to the method, high-efficiency, high-purity, low-energy-consumption and short-process preparation of terbium 149 is realized, and the large-scale production requirements of targeted alpha therapy on high-purity and short-half-life alpha nuclide can be met.
Owner:GUANGZHOU ZHONGKE NUCLEAR & JIAN PHARMACEUTICAL TECHNOLOGY CO LTD

Method and system for real-time analysis of elution profiles for at-211 purification processes

The application provides an elution curve real-time analysis method and system for At-211 purification process, relates to the technical field of signal analysis, generates elution curve data by real-time sampling of continuous detection signals output by a chromatographic separation device, sets time constraints for elution determination and divides multiple determination time windows in combination with the radioactive half-life characteristics of At-211 and the allowed activity loss requirements; a reference elution baseline is constructed and updated during the elution process, the difference change of the elution curve relative to the reference elution baseline is analyzed, candidate elution state determination, effective elution interval determination and elution end determination are sequentially completed, and then the starting and ending collection time of the eluent is determined, so that the segmented collection control of the At-211 eluent is realized; the method can continuously determine the elution state within a controlled time range and is suitable for the purification process of radionuclides.
Owner:FUJIAN RUISIKE MEDICAL TECHNOLOGY CO LTD

Intelligent management method for radioactive contaminated clothing and related equipment

PendingCN122117289AReduce peak exposureReduce cumulative exposureDosimetersCo-operative working arrangementsHalf-lifeEngineering
The application discloses a kind of radioactive contaminated clothing intelligent management method and related equipment.The method comprises the following steps: collecting the initial radiation dose of the contaminated clothing and generation time;Based on the nuclide decay formula, a decay tracking calculation process is constructed, the current dose is calculated in real time according to the nuclide half-life parameter, and the total dose is obtained by superimposing the contribution of each nuclide when there is multi-nuclide contamination;The current dose calculated in real time is compared with the preset control threshold, and the washable instruction is pushed to the medical terminal when the control threshold is met, and the remaining decay time prompt is output when the control threshold is not met.It can solve the problem that the management of radioactive contaminated clothing is highly dependent on manual, which can easily lead to waste of manpower, missed or wrong recording, and occupational health hazards caused by frequent close contact of medical staff with high-activity contaminated clothing during manual monitoring.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Iodine 131 treatment patient discharge monitoring system

The invention provides an iodine-131 treatment patient discharge monitoring system, and the method comprises the steps: carrying out the initialization modeling, and generating an initial attenuation curve based on a physical half-life period; introducing a composite attenuation model containing double components of physical decay and biological metabolism; periodically receiving actually measured environment dose rate data reported by the patient terminal; performing intelligent dynamic calibration on metabolic component parameters in the composite model by using time sequence measured data to generate a personalized dynamic attenuation curve; predicting a future accumulated exposure dose based on the curve and performing risk assessment; customized closed-loop safety intervention is automatically executed according to an evaluation result, and the method relates to the technical field of medical health information technology and radiation protection, and realizes conversion from static general management to dynamic precise intelligent protection by deeply fusing a theoretical physical model, an individual physiological metabolism model and real-time monitoring data. And the accuracy, the initiative and the compliance of radiation safety risk management are remarkably improved.
Owner:QIQIHAR FIRST HOSPITAL