186 results about "Metal chelate" patented technology

The invention relates to the technical field of biological separation materials, and discloses an amine-functionalized magnetic nano composite material and application thereof in protein separation and purification. The material has a core-shell structure and comprises a magnetic ferroferric oxide nano core, an ordered mesoporous silicon dioxide intermediate layer and a covalent grafted polyethyleneimine functional layer. By controlling the matching relationship between the pore diameter of mesopores and the molecular size of the polymer and adopting a crosslinking strategy, the material has high magnetic responsiveness, rapid mass transfer performance and high-density surface amino groups. The material shows high adsorption capacity, rapid adsorption kinetics and good cycle stability in the protein separation process, and is suitable for enrichment purification and metal chelating affinity separation of protein in a biological sample. According to the invention, the technical problems of low protein adsorption capacity, slow dynamics and poor cycling stability caused by compact shell layer, non-uniform amino distribution and limited mass transfer of the existing amine functionalized magnetic material are solved.

The invention belongs to the technical field of wastewater treatment, and particularly discloses a treatment method for complex-component mine acid wastewater. The method comprises the following steps: introducing wastewater into a primary mixing reaction tank, and respectively adding an alkaline agent, powdered zeolite and a heavy metal capturing agent to adjust the pH value and remove organic nitrogen and NH3-N to form a heavy metal chelate precipitate; pressurizing effluent in the first-stage mixing reaction tank to a first-stage efficient cyclone water purifier, carrying out solid-liquid separation, and introducing the wastewater into an efficient denitrification filter to adsorb organic nitrogen; introducing the filtrate in the efficient denitrification filter into a secondary mixing reaction tank, and then respectively adding a heavy metal capturing agent, a defluorination agent and NaClO; pressurizing the wastewater in the second-stage mixing reaction tank to a second-stage efficient cyclone water purifier, then introducing the wastewater into an efficient manganese removal filter, then introducing filtrate into a clean water tank, and finally calculating the removal rate n of each pollutant. The method has the characteristics of high treatment efficiency, simplicity and convenience in operation, stability in operation and low cost.

The invention relates to high-flame-retardant polypropylene resin for a new energy automobile and a preparation method of the high-flame-retardant polypropylene resin, and belongs to the technical field of high polymer materials. The high-flame-retardant polypropylene resin is prepared from the following raw materials: polypropylene, maleic anhydride grafted polypropylene, POE grafted acrylic acid, LLDPE grafted maleic anhydride, Si-APP (at) BN, a bio-based phytic acid metal chelate, nano titanium carbide, a TPC polyester elastomer, nano cerium oxide and silicone powder. Si-APP (at) BN is an organic silicon modified ammonium polyphosphate (at) boron nitride core-shell structure material obtained by coating the surface of nano boron nitride with Al2O3, then polymerizing ammonium polyphosphate and grafting vinyl trimethoxy silane. The POE grafted acrylic acid, the LLDPE grafted maleic anhydride, the Si-APP coated BN, the bio-based phytic acid metal chelate, the TPC polyester elastomer and other components have a synergistic effect, a heat conduction-flame retardant network is constructed, and the bottleneck of the prior art is broken through through molecular structure design and process innovation.

The disclosed method of treating a malignant solid tumor in a subject includes the steps of administering to the subject an immunomodulatory dose of a radioactive phospholipid ether metal chelate, a radiohalogenated phospholipid ether, or other targeted radiotherapy (TRT) agent that is differentially retained within malignant solid tumor tissue, and either (a) performing in situ tumor vaccination in the subject by introducing into at least one of the malignant solid tumors one or more agents capable of stimulating specific immune cells within the tumor microenvironment, or (b) performing immunotherapy in the subject by systemically administering to the subject an immunostimulatory agent, such as an immune checkpoint inhibitor. In a non-limiting example, the radioactive phospholipid ether metal chelate or radiohalogenated phospholipid ether has the formula:wherein R1 comprises a chelating agent that is chelated to a metal atom, wherein the metal atom is an alpha, beta or Auger emitting metal isotope with a half-life of greater than 6 hours and less than 30 days, or wherein R1 comprises a radioactive halogen isotope. In one such embodiment, a is 1, n is 18, m is 0, b is 1, and R2 is —N+(CH3)3.

The invention discloses an odorless temperature-controlled asphalt additive, odorless temperature-controlled asphalt and a preparation method of the odorless temperature-controlled asphalt. The odorless temperature control asphalt additive comprises the following components in parts by weight: 1-5 parts of odorless temperature control microcapsules; 1-5 parts of an auxiliary deodorant; 1-5 parts of a dispersant; the odor-removing temperature-control microcapsule comprises a composite shell material and a core material, the composite shell material comprises silicon dioxide / nano tourmaline / polydopamine, the core material comprises n-alkane with the phase change temperature of 40-60 DEG C, and a metal chelate and a smoke suppression compound containing active alpha-H are loaded on the surface of the composite shell material. The odorless temperature-controlled asphalt additive can efficiently and durably reduce the content of irritant gas in asphalt smoke, reduce the content of volatile organic compounds released by an asphalt pavement at high temperature, improve the high-temperature stability of asphalt and prolong the service time of the asphalt pavement, and provides a brand new idea for long-life and environment-friendly utilization of asphalt.

The invention relates to the technical field of industrial flue gas purification, in particular to a desulfurization and denitrification integrated flue gas purification system and method.The desulfurization and denitrification integrated flue gas purification system comprises an integrated washing tower, and the washing tower sequentially comprises an atomization venturi section, a desulfurization section, a denitrification section, a desulfurization section and a denitrification section which are communicated in the flue gas flowing direction, and the atomization venturi section is used for conducting preliminary acceleration, cooling and dust particle pre-wetting on introduced flue gas; the rotational flow centrifugal section is used for enabling the flue gas and the washing liquid to generate strong rotary centrifugal motion so as to realize gas-liquid-solid primary separation and mass transfer; the boiling foam absorption section is used for enabling the washing liquid at the bottom of the tower to form a boiling foam layer through an air distribution device and flue gas with a specific flow speed so as to provide a huge gas-liquid contact area; the dehydrating and demisting section is used for separating liquid drops entrained in the purified flue gas; by skillfully combining NO trapping by metal chelating and wet desulfurization by calcium, alkali and method, the method is realized in a unique boiling centrifugal tower, dust removal, desulfurization and denitrification are synchronously and efficiently completed in one tower body, the system is compact, and the investment and operation cost is low.

An amido group-containing monomer composition contains 80.00 to 99.99 mass % of an amido group-containing monomer (a) of the following formula (1) and 0.01 to 20.00 mass % of a metal chelate complex (b) having carbonyl group as a ligand:wherein R1 represents a hydrogen atom or a methyl group, R2 represents a hydrocarbon group having a carbon number of 1 to 6, R3 represents a hydrocarbon group having a carbon number of 1 to 23, and R4 represents hydrogen or a methyl group.

The invention relates to the technical field of agricultural biology, and particularly discloses a preparation method and application of a Chinese herbal medicine extract fertilizer for enhancing immunity, the preparation method comprises the following steps: S1, performing water extraction and alcohol precipitation extraction on Chinese herbal medicine raw materials to obtain a Chinese herbal medicine extracting solution and medicine residues; s2, crushing the obtained medicine residues, inoculating white-rot fungi or bacillus subtilis, and performing solid-state fermentation at the fermentation temperature of 25-35 DEG C for 5-7 days to obtain a fermentation product; s3, concentrating and drying the obtained Chinese herbal medicine extracting solution to obtain Chinese herbal medicine extract powder; s4, the obtained Chinese herbal medicine extract powder is mixed with humic acid, ferric salt or zinc salt is added, stirring reaction is conducted under the condition that the pH ranges from 5.0 to 6.5, and a Chinese herbal medicine-humic acid metal chelate is formed; chinese herbal medicine compound extraction and microbial solid fermentation are combined, and traditional waste medicine residues are converted into high-activity organic fertilizer carriers, so that efficient utilization of resources is realized, meanwhile, the immune induction function of the fertilizer is enhanced, and the disease resistance of crops is remarkably improved.

The invention provides a compound shown in a formula I or pharmaceutically acceptable salts, stereoisomers, isotope derivatives, solvates (such as hydrates), prodrugs, metal chelates, crystal forms or metabolites of the compound and application of the compound in the field of medicine. The compound can be used for treating and / or preventing psoriasis diseases, especially propafenone. The invention also finds that under the condition of the same administration dosage, the effect of smearing administration on treating psoriasis diseases is better than that of injection administration. Compared with a flecainib ointment with a similar anti-arrhythmia function, the propafenone ointment disclosed by the invention has a better effect on treating psoriasis diseases.

Provided is a film for forming a protective film, which is formed from a resin composition that contains a polymer component, a thermosetting component, a crosslinking agent component, an epoxy-modified silicone oil, and an inorganic filler. The polymer component is an acrylic polymer, the thermosetting component comprises epoxy resin and a thermosetting agent, and the cross-linking agent component comprises a metal chelate and polyisocyanate. In addition, based on the total weight of the resin composition as 100 weight percent, the content of the epoxy modified silicone oil is 0.01 weight percent to 0.2 weight percent. Therefore, according to the film for forming the protective film, the resin composition containing the epoxy modified silicone oil is added, so that the film can be quickly torn off as required after being thermally bonded with a semiconductor wafer, and the film has reworkability.

The invention relates to a method for determining the chelation effect and the chelation rate of a compound amino acid microelement chelate. According to the determination method, the chelation effect and the chelation rate of the compound amino acid microelement chelate are determined through combination of an infrared spectroscopy method, an elemental analysis method and an anhydrous titration method, and the chelation effect comprises an action form and action intensity. The determination method comprises the following steps: weighing a compound amino acid trace metal chelate sample; taking a part of the to-be-detected powder and potassium bromide crystals, grinding together, pressing, measuring the infrared spectrum of the powder, and analyzing the chelation type and strength; taking another part of the to-be-detected powder, measuring the nitrogen content of the to-be-detected powder through an elemental analysis method, and calculating the total amount of amino acids in the sample; taking another part of the to-be-detected powder, removing inorganic salt in the to-be-detected powder, and drying; and dissolving the obtained solid powder, titrating without water, carrying out a blank experiment to eliminate the influence of reducing substances in the solution, and calculating to obtain the chelation rate. The method is simple and easy to operate and high in accuracy.

The present invention provides a nickel ion metal chelate affinity chromatography medium and a preparation method thereof. The nickel ion metal chelate affinity chromatography medium uses porous dextran gel microspheres as a matrix, and allyl glycidyl ether is bonded to the surface of the dextran gel microspheres. The allyl glycidyl ether is connected to ethylenediaminetetraacetic acid, and the ethylenediaminetetraacetic acid is complexed with nickel ions. The nickel ion metal chelate affinity chromatography medium uses the ethylenediaminetetraacetic acid to bond with allyl glycidyl ether, and the ethylenediaminetetraacetic acid can bind nickel ions. 2+ Carry out complexation and effectively improve the stability of chromatography media.

The application discloses a demetallization agent, a preparation method and application method thereof, and a use of a demetallization auxiliary agent. The demetallization agent comprises a core-shell structure, is composed of an organic material with a chelating functional group, and comprises a core and a shell layer. The core is a sub-micron organic polymer particle, and the shell layer is an amphiphilic polymer with a functional group of strong electrostatic adsorption and metal chelating capacity connected to the surface. The preparation method of the demetallization agent comprises the steps of initiating connection and preparing the demetallization agent. The demetallization auxiliary agent has strong chelating capacity in an aqueous phase, and can transfer the metal chelated by the demetallization agent to the demetallization auxiliary agent. In addition, the application of the demetallization agent and the demetallization auxiliary agent to non-acid crude oil demetallization is disclosed. The demetallization agent and the demetallization auxiliary agent are suitable for removing metals such as nickel and vanadium in crude oil, have high demetallization agent grafting rate, increase the contact time of the demetallization agent and the oil phase, and have the characteristics of low cost, easy production and environmental friendliness.

The problem of the present invention can be solved by an adhesive which contains a specific acrylic copolymer (A), an isocyanate compound (B), and a metal chelate (C), and which satisfies all of the following (1)-(3) after curing. (1) 3.0 * 10 < 4 > Pad; g '(-20) lt; 4.0 * 10 < 5 > Pa, (2) 5lt; g '(-20) / G' (200) lt; 17, (3) 2lt; tan delta (-20) / tan delta (200) lt; 6.5); wherein in the formula, G '(-20) refers to the storage modulus at-20 DEG C and 1 Hz, G' (200) refers to the storage modulus at 200 DEG C and 1 Hz, tan delta (-20) refers to the loss tangent at-20 DEG C and 1 Hz, and tan delta (200) refers to the loss tangent at 200 DEG C and 1 Hz.

The present disclosure provides for a metal chelated polyol liquid and / or a metal chelated polyether polyol liquid that can be used in an isocyanate-reactive composition and a reaction mixture for forming a polyurethane polymer. The metal chelated polyester polyol liquid is a reaction product of a chelating polyester polyol having a chelating moiety and a metal compound having a metal ion. The metal chelated polyether polyol liquid is a reaction product of a chelating polyether polyol having a chelating moiety and a metal compound having a metal ion. The chelating moiety of the chelating polyester polyol or the chelating polyether polyol chelates the metal ion to form the metal chelated polyester polyol liquid or the metal chelated polyether polyol liquid, respectively, having a mole ratio of the metal ion to the chelating moiety of 0.05:1 to 2:1.

There is provided a resin composition including a resin having an alkyl group on a side chain of a molecule thereof, an inorganic filler and an antioxidant, wherein the antioxidant is either of a hydrazide-based antioxidant or a combination of a hindered phenol-based antioxidant and an organic metal chelate-based antioxidant.

The invention belongs to the technical field of catalytic materials, and particularly discloses an ionic liquid catalyst for preparing methylacrolein and a preparation method of the ionic liquid catalyst. According to the preparation method, ionic liquid (protonated morpholine hydrochloride or 1-butyl-3-methylimidazole chloride salt) and metal chloride are subjected to a reaction, metal chelating ionic liquid is obtained, and the ionic liquid catalyst is obtained. The ionic liquid catalyst disclosed by the invention is simple in synthesis operation and mild in reaction condition, and has good industrial amplification potential; compared with the traditional supported or single metal salt catalyst, the catalyst provided by the invention has the advantages that the metal ion loss or agglomeration phenomenon is not easy to occur in the use process, the service life of the catalyst is effectively prolonged, and the problem that the existing catalyst is easy to inactivate is solved; the catalyst is adjustable in active center, high in selectivity and excellent in catalytic performance.

The invention relates to a preparation method and application of a releasing agent, and belongs to the technical field of steroid hormone releasing agents. The releasing agent is prepared from the following components in percentage by mass: 0.2 to 1 percent of an amide compound, 0.02 to 0.06 percent of a metal chelate, 0.05 to 0.15 percent of a preservative, 0.2 to 0.5 percent of a surfactant, 0.015 to 0.045 percent of a steroid heterocyclic compound and the balance of deionized water, wherein the amide compound is a composition of sodium alpha-mercaptoethanesulfonate and N-methylacetamide, and the amide compound is a compound of sodium alpha-mercaptoethanesulfonate and N-methylacetamide; the steroid heterocyclic compound is a composition of methyltestosterone, danazol and stanolone. According to the universal releasing agent, the four hormones in a sample can be effectively released from respective binding proteins to be in a free state, and clinical test data of the sample can be obtained by measuring the content of the free hormones, so that the measured test result is more accurate.

The invention discloses a biomass waste-based compost fertilizer for improving saline-alkali soil and a preparation method thereof, and belongs to the technical field of fertilizer preparation, the compost fertilizer comprises the following raw materials: a biomass waste basic mixture, charcoal, desulfurized gypsum, zeolite powder, hydroxyapatite, sodium lignin sulfonate, EDTA-metal chelate and polyaspartic acid; the biomass waste base mixture comprises animal waste, crop straw and agricultural product processing by-products. On the basis of a biomass waste resource utilization concept, the compost fertilizer with a multi-mechanism synergistic effect is constructed through precise compatibility of components such as the biochar, the desulfurized gypsum, the zeolite, the hydroxyapatite, the natural polymer and the metal chelate and optimization of a two-stage fermentation and aging process, and aims to break through the bottleneck of the prior art. An innovative solution is provided for green and sustainable improvement of the saline-alkali soil.

The present application relates to systems and methods for purifying polypeptides, such as His tagged polypeptides, using immobilized metal chelate affinity chromatography (IMAC). The method comprises loading a composition comprising the polypeptide onto an IMAC matrix; eluting the polypeptide from the first IMAC matrix; performing buffer exchange to remove the elution buffer from the first eluate; loading the first eluate from the buffer exchange onto a second IMAC substrate; eluting the polypeptide from the second IMAC matrix; and optionally purifying the eluate from the second IMAC matrix using size exclusion chromatography. In some aspects, the method is fully automated.

The present invention relates to the field of polypeptide compositions, and specifically relates to a polypeptide metal chelate and the use thereof in the field of cosmetics. The polypeptide metal chelate is formed by means of the chelation of a polypeptide compound with a metal ion compound. A structure of the polypeptide compound is: [γ-Glu]n-AA, wherein n≥1, and AA is selected from glycine, alanine, valine, leucine, isoleucine, methionine (Met), proline, tryptophan, serine, tyrosine, cysteine, phenylalanine, asparagine, glutamine, threonine, aspartic acid, glutamic acid, lysine, arginine or histidine. The polypeptide zinc chelate prepared by the present invention has significant oil-controlling and anti-inflammatory effects, and can be compounded with other raw materials to prepare cosmetics with oil control and acne removal effects.

The application discloses a high-strength, large-pore-volume phosphorus-containing binder, characterized in that the binder comprises a glue, a curing agent and a modifier; the glue comprises a phosphorus-containing compound and an aluminum-containing compound; the curing agent comprises a gamma-aluminum oxide precursor, an acid and an alkylammonium salt, and the modifier is a metal chelate; wherein the colloidal solubility index of the gamma-aluminum oxide precursor is less than or equal to 50%; and the modifier is reacted with the glue in a high-shear dispersion emulsifier. The phosphorus-containing binder provided by the application, in combination with a conventional method, can obtain a catalytic cracking catalyst which, on the basis of high molecular sieve content and large pore volume, still has high wear resistance.

The problem of the present invention is solved by an adhesive comprising a specific acrylic copolymer (A), an isocyanate compound (B), and a metal chelate compound (C), the adhesive after curing satisfying all of (1) to (3). (1) 3.0 × 104 Pa < G'(-20) < 4.0 × 105 Pa; (2) 5 < G'(-20) / G'(200) < 17; (3) 2 < tanδ (-20) / tanδ (200) < 6.5. In the abovementioned formulas, G'(-20) represents the storage elastic modulus at -20°C and 1 Hz, G'(200) represents the storage elastic modulus at 200°C and 1 Hz, tanδ (-20) represents the loss tangent at -20°C and 1 Hz, and tanδ (200) represents the loss tangent at 200°C and 1 Hz, respectively.

Disclosed is the use of dihydroporphin derived from chlorophyll as a plant growth regulator. Compared with the prior art, a class of new type plant growth regulators are provided; since the direct decomposition product of chlorophyll is used as a product, the preparation and processing thereof are easier, the structure is relatively simple, and tedious reactions and preparations such as further chemical coordination / chelation / purification are eliminated, so that the product is more environmentally friendly and safer; the product has a better solubility than the corresponding metal chelate and has a more convenient method of use, making it more convenient to be used in the fields; the stability of the product has been improved, with stable quality assurance and a longer shelf life; the product has a natural source and uses a low amount of same due to a low effective dosage, thereby improving the utilization rate of silkworm excrement resources.

An adhesive includes: a resin binder including an acrylic polymer and carboxylic acid; metal chelate hardener; and epoxy-based hardener.

The invention discloses a special fertilizer for honeysuckle as well as a preparation method and application of the special fertilizer. The fertilizer is prepared from the following components in percentage by mass: 80-85% of a core granular material and 15-20% of a film coating layer material, wherein the core particle material is prepared from the following raw materials in percentage by mass: 30-35% of organic matters, 10-12% of an alkali reducing agent, 15-18% of a slow-release nitrogen source, 3-5% of a metal chelate, 6-8% of a water-retaining agent, 2-3% of a microbial agent and the balance of a binder, and the film coating layer material is composed of an inner-layer material and an outer-layer material. The inner-layer material is prepared from the following components in percentage by mass: 60-70% of polyvinyl alcohol, 20-30% of a nano inorganic reinforcing agent and 5-10% of a plasticizer, and the outer-layer material is a biodegradable high polymer material; according to the invention, the alkalinity of the saline-alkali soil is effectively improved, the pH value and EC value of soil are reduced, the survival rate of microbial bacteria in the fertilizer is increased, and the release time of fertilizer nutrients is prolonged.

The present application relates to the field of environment-friendly metal surface pretreatment technology, and discloses a metal chelating film forming agent, a preparation method and application thereof, wherein low-molecular polysilazane resin and zirconium triethanolamine compound are used as film forming agents, epoxy modified silicone resin is used as an auxiliary film forming agent, aspartic acid diacetic acid tetrasodium is used as a chelating dispersant, tetramethyl decyne glycol is used as a wetting agent, n-butanol is used as a leveling agent, and interface stable graphene with Schiff base functional groups, quinoline functional groups and quaternary ammonium salt functional groups on the surface is used as a corrosion-resistant filler to prepare the metal chelating film forming agent, wherein the present application is environmentally friendly, and after the leak detection process of the compressor muffler, no alkaline cleaning agent is needed for cleaning and treatment, and the subsequent spraying can be directly performed, on the other hand, the metal substrate surface can be combined by physical adsorption and chemical adsorption to produce strong bonding force, and a dense protective film is formed on the metal substrate surface, thereby achieving the beneficial technical effect of significantly improving the corrosion resistance.

This invention provides a binder for a catalytic cracking catalyst and its preparation method. The binder comprises a binder, a curing agent, and a modifier. The curing agent is prepared by a hydrothermal reaction of a γ-alumina precursor, an acid, and an alkylammonium salt. The modifier is prepared by reacting a multi-metal chelate ligand, a metal central ligand, ethanol, and an organic acid. The binder comprises a phosphorus-containing compound and an aluminum-containing compound. In the binder for the catalytic cracking catalyst provided by this invention, a multi-metal chelate modifier composed of a multi-metal chelate ligand and multiple metals is introduced. Under the promotion of organic acid and ethanol, a multi-metal chelate modifier can be prepared in situ during the binder preparation process. Compared with directly using commercially available metal chelates, the in-situ prepared multi-metal chelate modifier has better water solubility and can promote the binding of the modifier with the phosphorus-aluminum sol, resulting in a better modification effect.

The invention belongs to the technical field of extraction and purification of natural active substances, and discloses an anti-inflammatory active melanoidin based on black American ginseng as well as a preparation method and application of the anti-inflammatory active melanoidin, and the black American ginseng melanoidin with anti-inflammatory activity is obtained by performing separation and purification by utilizing the metal chelating property of the melanoidin. The content of the anti-inflammatory active melanoidins is 63.29-73.52 g / 100g, the molecular weight distribution range is 4.6 * 10 < 2 >-2.49 * 10 < 4 > Da, the average molecular weight is 17.46 kDa, and the anti-inflammatory active melanoidins are of uniform rod-shaped and sheet-shaped structures. A skeleton in the black American ginseng melanoidin with anti-inflammatory activity is rich in C = O, C-N and N-H groups, characteristic absorption peaks of amide, carboxyl and the like appear at 1600cm <-1 > of a separated product, the influence of the separated product on LPS-induced Caco-2 colon cancer cells is researched through an in-vitro cell experiment, and a research result shows that the melanoidin isolate has a relatively remarkable anti-inflammatory effect.

The invention discloses an environment-friendly sunlight-resistant microcapsule, an environment-friendly sunlight-resistant asphalt additive and a preparation method of the environment-friendly sunlight-resistant microcapsule. The environment-friendly sunlight-resistant microcapsule comprises a shell material and a core material, the shell material is a composite shell material comprising titanium dioxide / nano tourmaline / polydopamine, the core material is n-alkane with the phase change temperature of 40-60 DEG C, and a metal chelate and a light stabilizer are loaded on the surface of the shell material. Through the temperature control effect, the ultraviolet aging resistance and the in-situ trapping effect of the environment-friendly sunlight-resistant microcapsule, the damage of asphalt caused by the influence of high temperature and ultraviolet is reduced, the service time of the asphalt pavement is effectively prolonged, meanwhile, the amount of small molecular compounds released by the asphalt pavement caused by the influence of high temperature is reduced, and the environmental problem existing in the asphalt pavement is solved.