85results about "Hydroxy compound separation/purification" patented technology

This invention belongs to the technical field of medicinal chemistry, specifically relating to a novel crystal form of cariprazine, specifically the cariprazine-4-hydroxybenzoic acid-methanol-hemihydrate crystal form and its preparation method. The novel cariprazine-fumaric acid crystal form provided by this invention comprises a basic unit of one molecule of cariprazine, one molecule of 4-hydroxybenzoic acid, one molecule of methanol, and 0.5 molecules of water. Its preparation method is simple to operate, the crystallization process is easy to control, and it has good reproducibility. The formation of a eutectic significantly enhances the solubility of cariprazine, exhibiting strong pharmaceutical value.

This application discloses an integrated method and system for the co-production of MTO methanol and refined methanol, belonging to the field of chemical technology. The co-production method provided by this application includes: feeding crude methanol into a light-duty removal distillation column for pre-distillation treatment to obtain a pre-distillation column bottom component; dividing the pre-distillation column bottom component into two streams, one as the output of MTO methanol and the other as a reprocessed component of the pre-distillation column bottom; feeding the reprocessed component of the pre-distillation column bottom into a refined methanol distillation column for distillation treatment to obtain a distillation column top component and a distillation column bottom component; at least a portion of the distillation column top component is output as refined methanol, and the distillation column bottom component is returned to the light-duty removal distillation column. This application achieves the co-production of refined methanol using only two columns, eliminating the need for additional independent equipment, significantly reducing equipment investment costs, and enabling flexible adjustment of both MTO methanol and refined methanol products, thus possessing broad application prospects in the industrial-grade MTO methanol field.

This application relates to the field of organic synthesis technology, specifically disclosing a process for preparing tert-butyl vinyl ether. The raw materials include solid tert-butanol, acetylene, tetrahydrofuran solvent, and potassium hydroxide catalyst, supplemented with auxiliary materials such as type 3A molecular sieves and activated alumina adsorbents. The preparation method involves: after dehydration and purification of the raw materials, the materials are introduced into a reaction vessel; temperature and pressure are controlled, and the reaction endpoint is monitored using an infrared spectrometer; byproducts are quenched and acetylene is recovered; the process involves multi-stage condensation, water washing to remove impurities, distillation separation, and solvent purification and recycling, with simultaneous integration of waste heat recovery and continuous material feeding. The tert-butyl vinyl ether prepared by this process, as an important fine chemical intermediate, can be used in coatings, adhesives, and polymer material modification, possessing advantages such as high purity and good stability. The preparation method achieves efficient utilization of materials and energy through multi-stage synergistic linkage, combining the advantages of green environmental protection, continuous and stable operation, and high resource utilization.

The utility model relates to corn soaking water treatment technical field especially, relates to a kind of production system for preparing ammonium magnesium phosphate and inositol with corn soaking water, including the pH regulating tank being connected with corn soaking water delivery pipeline, pH regulating tank, first filter device, resin column, neutralization kettle, second filter device, hydrolysis kettle, pH adjusting kettle, third filter device are sequentially connected in proper order, the liquid outlet of third filter device is connected with decoloring kettle, concentration kettle, crystallization kettle, the crystal outlet of crystallization kettle is connected with first drying device, the discharge port of first drying device is connected with inositol storage tank;The discharge port of third filter device is connected with second drying device, the discharge port of second drying device is connected with ammonium magnesium phosphate storage tank.The above-mentioned production system system, corn soaking water is recycled, and high yield, high recovery, high-purity ammonium magnesium phosphate product and inositol product are obtained, and resource waste is avoided, and economic benefit is increased for enterprise.

The application discloses a kind of purification process systems and methods of glycerin for injection, system includes ion exchange unit, oxidation unit, water removal unit, decolorization unit, purification unit in turn fluid communication, ion exchange unit receives upstream industrial glycerol raw material, the glycerol product that the purification unit exports meets the standard for injection.Industrial glycerol is treated in ion exchange unit in turn, and the treatment of removing aldehydes and reducing substance is carried out in oxidation unit, water removal unit is handled in water removal unit, decolorization unit is handled in decolorization unit, and after the deep purification treatment of purification unit, industrial glycerol can be purified to glycerol product meeting each index requirement of glycerol (for injection) in Chinese Pharmacopoeia (2025 edition).

The utility model relates to a kind of chloromethane by-product dilute sulfuric acid concentration recycling device, including with the organic matter separation system being connected with concentration system, organic matter separation system includes sequentially connected hydrolytic kettle, organic matter thermal separation equipment, primary condenser and secondary condenser;Hydrolytic kettle is connected with chloromethane by-product dilute sulfuric acid delivery pipe, desalted water pipeline, hydrogen peroxide delivery pipe respectively, primary condenser is communicated with condensate tank, the condensate tank is communicated with hydrolytic kettle, secondary condenser is communicated with methanol recovery tank, gas phase pipeline respectively, methanol recovery tank is communicated with chloromethane synthesis device;Organic matter thermal separation equipment is communicated with dilute sulfuric acid heater, dilute sulfuric acid heater is communicated with concentration system.The utility model is concentrated before dilute sulfuric acid, first organic matter is separated out in dilute sulfuric acid, not only increase economic value, but also reduce the subsequent dilute sulfuric acid vacuum concentration system's jam risk, improve the operation stability of dilute sulfuric acid vacuum concentration system.

The present invention relates to a method for preparing 3-methyl-2-butenal (prenal), 3-methyl-2-buten-1-ol (prenol), diprenyl acetate of prenal, and 3,7-dimethyl-octa-2,6-dienal (citral), wherein the aldehyde content in one or more reaction flows is maintained below a threshold. Furthermore, the present invention relates to available product flows of prenal, prenol, diprenyl acetate of prenal, and citral.

The application provides a core-shell structure composite adsorbent, a preparation method and application thereof; the core-shell structure composite adsorbent is prepared by adopting a one-step co-precipitation-thermal immersion process to prepare a core-shell structure from ZIF-8 and UiO-66-NH2, and then performing sulfonation modification, dispersing in a polyvinyl alcohol solution, drying and performing thermal solidification to complete coating; the preparation process is environment-friendly and efficient, and can realize gradient capture of aldehydes, ketones, carboxylic acid esters, aromatic hydrocarbons and metal ions. When the core-shell structure composite adsorbent is regenerated, a low-pressure steam and hydrogen / nitrogen mixed gas blowing combination mode is adopted, and the adsorption capacity attenuation is small after multiple cycles, the defects that the existing single MOF material or adsorption technology cannot simultaneously remove polar, non-polar impurities and metal ions are solved, the application limitations of the existing catalytic membrane or single coating technology are avoided, and the core-shell structure composite adsorbent has a good industrial application prospect.

The application provides a method for separating cis and trans 2,2,4,4-tetramethyl-1,3-cyclobutanediol, comprising the following steps: cooling a mixed solution containing a solvent, cis and trans 2,2,4,4-tetramethyl-1,3-cyclobutanediol to a first temperature at a first cooling rate, then cooling to a second temperature at a second cooling rate, and performing solid-liquid separation to obtain mixed crystals; performing screening treatment on the mixed crystals to obtain cis and trans 2,2,4,4-tetramethyl-1,3-cyclobutanediol crystals; wherein the first cooling rate is less than or equal to 10 DEG C / h, and the second cooling rate is greater than or equal to 30 DEG C / h; the first temperature is higher than the second temperature, the temperature of the mixed solution is greater than the first temperature, the first temperature is less than or equal to 70 DEG C, and the second temperature is less than or equal to 30 DEG C. The method can efficiently and simply separate cis and trans 2,2,4,4-tetramethyl-1,3-cyclobutanediol crystals.

This invention relates to the field of ethylene glycol preparation, specifically to a method for the direct production of ethylene glycol from ethylene. The method includes: reacting ethylene with hydrogen peroxide in the presence of an oxidative hydration bifunctional catalyst to obtain a material containing ethylene glycol, and collecting the product after separation via a metal-ceramic composite membrane. Using this method, ethylene glycol can be produced in a one-step process. The reaction exhibits high hydrogen peroxide utilization, ethylene conversion rate, and ethylene glycol selectivity, along with high catalyst activity and stability. During separation, the transmembrane pressure difference is small, allowing the separation system to operate continuously for extended periods. The resulting product liquid has a low catalyst concentration.

The application provides a method for synthesizing 2,4,4-trimethyl-2-pentanol from diisobutene by esterification hydration, comprising the following steps: S1, esterification hydration reaction: diisobutene, organic acid and water are reacted in the presence of a catalyst; S2, separation and recovery: S3, hydrogenation reaction: 2,4,4-trimethyl-2-pentyl acetate recovered in step S2.5 is subjected to catalytic hydrogenation to generate a hydrogenation reaction liquid containing 2,4,4-trimethyl-2-pentanol and ethanol; S4, the hydrogenation reaction liquid obtained in step S3 is separated, and TMPOL is synthesized by using the above method with the organic acid as a medium, the single-pass conversion rate of diisobutene can reach 50%, and the selectivity reaches 99%. The process has the characteristics of high efficiency and high atom economy, and has great industrialization potential.

This invention discloses an enzyme preparation and a method for preparing squalene, belonging to the field of genetic engineering technology. The enzyme preparation includes inositol-2-dehydrogenase and squalene dehydrogenase. The amino acid sequence of inositol-2-dehydrogenase is shown in SEQ ID NO. 6, and the amino acid sequence of squalene dehydrogenase is shown in SEQ ID NO. 8 or SEQ ID NO. 10. This invention mutates wild-type inositol-2-dehydrogenase and wild-type squalene dehydrogenase to obtain specific amino acid sequence mutants: inositol-2-dehydrogenase mutant D270P, squalene dehydrogenase mutant H89L, and squalene dehydrogenase mutant H89L / A294R. These mutants exhibit higher enzyme activity, effectively improving the yield and conversion efficiency of squalene during preparation.

This invention provides a method for removing reboilers during propylene glycol refining, relating to the field of propylene glycol refining technology. This invention splits the material in the bottom of the propylene glycol de-refining tower into a first material stream and a second material stream, and implements differentiated vaporization rate control: by precisely controlling the vaporization rate of the first material stream to be significantly lower than that of the second material stream, the overall residence time of reboilers in the refining system is effectively shortened. This not only significantly inhibits the occurrence of side reactions and improves the product yield of propylene glycol, but also reduces reliance on additional high-energy-consuming post-processing equipment, thus reducing equipment investment costs. Compared with traditional reboiler removal processes, this invention can alleviate the problem of pipeline and equipment blockage caused by reboiler accumulation at the source, and has outstanding advantages of low energy consumption and strong operational stability. While ensuring product quality, it achieves simultaneous improvement in process economy and operational reliability.

The application discloses a kind of alcohol wastewater multistage separation and waste heat integration device and method, device includes vertical coaxial tower body, gas purification section, extraction rectification section, pre-concentration section and heat exchange liquid collection section are integrated from top to bottom in it.The extraction rectification section is equipped with self-cleaning tray system, and the inclined hole is prevented from being blocked in cooperation with the injection cover.The heat exchange liquid collection section is built-in spiral coil type reboiler, and the heat medium inlet is connected with the extraction section bottom rich solvent outlet, to form internal energy circulation;Device outside is equipped with multi-section jacketed preheating heat exchange unit, recovers system waste heat gradient preheats raw material wastewater, forms external energy recovery network.The method includes raw material preheating, pre-concentration, extraction separation, internal energy circulation and discharge steps.The application highly integrates multistage separation function, substantially reduces energy consumption by internal and external double-circulation energy network, and uses self-cleaning tray to ensure long-term stable operation, with the advantages of compact equipment, significant energy saving, reliable operation.

The present application relates to a kind of methyl methacrolein oxidation esterification reaction product separation method, comprising: (1) the methyl methacrolein oxidation esterification reaction product of pretreatment is sent to demethyl methacrolein tower, and removes most of the unreacted methyl methacrolein therein;(2) the demethyl methacrolein tower tank product is mixed with water, and after obtaining mixture stream, it is entered into extraction tower, is extracted with lean solvent stream, and from the top, it is obtained that the solvent stream is rich, and from the tank, it is obtained that the aqueous phase stream;(3) the solvent stream is rich and is sent to washing tower, and after being washed with water, it is obtained that the solvent stream is washed after being washed and is sent to solvent recovery tower;(4) the solvent recovery tower top is obtained that the recovered lean solvent stream is used as extraction solvent in step (2) and is recycled, and the crude methyl methacrylate product is obtained from the tank of solvent recovery tower;(5) the crude methyl methacrylate product is refined and is obtained that the methyl methacrylate product;(6) the aqueous phase stream of step (2) is sent to methanol recovery tower, and the obtained methanol is recovered and returned to methyl methacrylate reaction unit.

A method of preparing isopropyl alcohol that allows separation of a reaction product stream formed by reacting a propylene monomer and water in a reactor into an unreacted propylene monomer and isopropyl alcohol with high purity using an absorption column, a gas purification column, and an inert gas removal column.

This invention relates to the field of polymer material degradation and recycling technology, and provides a process for the efficient degradation of PET using alcoholysis under low-temperature conditions, comprising the following steps: S1, raw material preparation and degradation reaction: waste PET fragments and ethylene glycol are added to a reaction vessel, stirred at 120-150℃, a composite catalyst is added, and the degradation temperature and pressure are controlled. The reaction is carried out for 2-6 hours to obtain a reaction solution; S2, separation: the reaction solution is filtered to separate solid and liquid components. The solid component enters the recycling system, and the liquid component enters the recrystallization system; S3, recrystallization: water is added to the recrystallization system, the mixture is cooled and crystallized, filtered, and the resulting solid enters the degradation system. The resulting liquid undergoes secondary crystallization. After crystallization, the solid obtained is filtered to obtain the product BHET, which is dried and collected. The filtered liquid enters the purification system; S4, purification; S5, crystallization. The preparation method of this invention provides a process for the alcoholysis degradation of PET, which has the advantages of low PET degradation temperature and high BHET yield.

The application discloses a kind of DMSO waste liquid recovery methods containing isopropanol, comprising the following steps: (1) DMSO waste liquid containing isopropanol is passed into crude distillation kettle, after adding lye to adjust pH, crude distillation treatment is carried out, fraction one and crude distillation residual liquid are obtained;(2) fraction one is passed into freezer and is subjected to freezing crystallization treatment, then centrifugal separation is carried out, solid and filtrate are obtained, solid is subjected to vacuum drying treatment, DMSO finished product is obtained, filtrate is passed into supergravity rectification device and is subjected to rectification treatment, fraction two and rectification residual liquid are obtained;(3) fraction two is passed into pervaporation membrane group and is subjected to dehydration treatment, isopropanol finished product is obtained.In the application, after neutralization, separation is carried out by crude distillation, the problem of low efficiency and high cost of traditional resin adsorption process is solved, the waste liquid is not heated and separated by freezing crystallization in the application, energy consumption is greatly saved, the process device of the application is simple, dimethyl sulfoxide and isopropanol can be effectively recovered, the application is easy to operate, and industrial production application is facilitated.

This invention relates to the field of chemical process treatment technology, and discloses a method and system for treating organic wastewater from ethanol dehydration to ethylene production. The invention first hydrogenates a mixed solution containing ethanol, diethyl ether, and acetaldehyde, converting acetaldehyde in the mixed solution into ethanol, effectively avoiding the impact of acetaldehyde accumulation on the dehydration catalyst. Then, the overhead gas from the stripping tower is collected to recover ethanol and diethyl ether from the aqueous phase, with recovery rates reaching over 99 wt%. This invention employs a "hydrogenation reaction + stripping" technology, effectively recovering and reusing ethanol and diethyl ether from the aqueous phase. It solves the problems of difficulty in separating the ternary azeotrope of diethyl ether, acetaldehyde, and water through distillation, acetaldehyde in the recovered product causing deactivation of the dehydration catalyst, and the high energy consumption caused by the need for condensation followed by vaporization of the recovered product.

The application discloses a kind of efficient preparation of left enantiomeric borneol crystal from Blumea Balsamifera and product, the method includes S1 supercritical CO2 extraction, S2 paste water separation, S3 impurity removal, S4 crystallization treatment and S5 crystal collection step.Using the method and the left enantiomeric borneol crystal prepared by the application, the whole preparation method is simple to operate, after supercritical CO2 extraction, the crude extract with less impurities can be obtained, then after column chromatography purification, Blumea Balsamifera crystal is obtained by induced crystallization, not only high preparation efficiency, and product quality is stable, far superior to traditional preparation method, greatly improve the comprehensive utilization rate of resources, also have guiding significance to left enantiomeric borneol product preparation and product application.

This invention provides a method for synthesizing an aqueous methanol solution from a mixed gas containing carbon dioxide and hydrogen under low pressure conditions of less than 1 MPa. [Solution] A method for synthesizing an aqueous methanol solution from a mixed gas containing hydrogen and CO2, wherein methanol and water vapor are generated from a raw material gas containing CO2 and hydrogen by a catalytic reaction in a first reactor, and then the separation layer is M n [Al n Si 96-n O 192 ](2

The utility model relates to residual liquid dehydration technical field, concretely relates to a butyl octanol residual liquid dehydration device, including support frame, still including the dehydration mechanism for to residual liquid dehydration, dehydration mechanism is located above support frame, dehydration mechanism includes the outer bucket setting above support frame, the dehydration bucket is fixed with in the outer bucket, the inside stirring structure of dehydration bucket is equipped for to residual liquid dehydration when carrying out stirring, the vibration structure that is used for driving the vibration of gas collecting hood is equipped with above gas collecting hood. Advantageous effects: through the residual liquid in dehydration bucket inside all -round stirring of stirring structure, makes the uniform mixing of light component and heavy component in residual liquid interior, prevents the stratification phenomenon of light component and heavy component, simultaneously when stirring residual liquid flows in a large range, contribute to residual liquid even heating, avoid partial residual liquid because of temperature is too high and takes place coking, carbonization etc. phenomenon, and then accelerated residual liquid's heat transfer efficiency, improved residual liquid dehydration's quality and efficiency.

The utility model relates to a kind of methanol plant fusel oil co-production anhydrous ethanol process method's device, realize the quality of methanol plant by-product fusel oil is handled, recover methanol in it while co-production anhydrous ethanol.The entire device at least includes dehydrating tower (T101), methanol tower (T102), ethanol tower (T103), stripping tower (T104) and four towers and membrane module (PU101) and its supporting equipment.It overcomes the defects of prior art, realizes the fine separation of waste fusel oil under lower energy consumption, improves the methanol yield while co-production anhydrous ethanol is realized, with significant practicality and economic benefits, wide application prospect.

The present disclosure relates to a method for purifying a 1,4-cyclohexanedimethanol (CHDM) composition, and more particularly, to a method for purifying CHDM that can efficiently remove water as a solvent with low energy and can separate high-purity CHDM.

The present application relates to a kind of glycol regeneration and recovery system based on electrodialysis desalination technology, belong to oil and gas exploitation technical field, applied to offshore oil and gas field and future natural gas hydrate exploitation.Its technical points are: including pretreatment unit, electrodialysis unit, double-effect evaporation unit, auxiliary system, vacuum unit, each part is connected by corresponding pipeline, constitute a kind of based on electrodialysis desalination, double-effect evaporation technology offshore natural gas hydrate exploitation glycol regeneration and recovery system, the present application introduces glycol electrodialysis desalination monovalent salt technology, glycol double-effect evaporation dehydration technology, auxiliary system self-circulation salt balance technology, with the advantages of environmental protection, low energy consumption, small volume, flexible arrangement, low operating cost.

The present invention relates to a system for a refinement processing of a xylitol fermentation broth, the system includes a fermentation tank, a post-fermentation tank, a ceramic membrane filter, a nanofiltration membrane filter, an activated carbon filter, ion exchange columns, an evaporation tank, a crystallization tank, a centrifuge, and a dryer, which are connected by pipelines. The post-fermentation tank is configured to store the xylitol fermentation broth obtained from the fermentation tank and obtain sediments and supernatant fermentation broth through a standing stratification processing. The ceramic membrane filter, the nanofiltration membrane filter, the activated carbon filter, and the ion exchange columns are configured to perform a filtration and impurity removal processing successively on the supernatant fermentation broth to obtain xylitol ion exchange liquid. The evaporation tank and the crystallization tank are configured to perform an evaporation and crystallization processing on the xylitol ion exchange liquid to obtain xylitol massecuite. The centrifuge is configured to perform a separation processing on the xylitol massecuite to obtain a crystal xylitol and mother liquor respectively. The dryer is configured to perform a drying processing on the crystal xylitol to obtain a refined xylitol crystal product. The present disclosure also discloses a method implemented on the system. The present disclosure significantly reduces an amount of activated carbons, increases a pH value of liquid, and significantly reduces an electrical conductivity and a load of a subsequent ion exchange processing.

The application belongs to the technical field of ethanol recovery, in particular to a membrane filtration ethanol recovery equipment, and proposes the following scheme: a support is provided with a raw material tank at the back side, the top of the raw material tank is connected with a feeding assembly, the end of the feeding assembly is connected with a heat exchange assembly, one side of the heat exchange assembly is connected with an evaporator, the inside of the evaporator is provided with an evaporation pipe, the back side of the evaporator is provided with a fan, and the bottom of the evaporator is provided with a liquid discharge valve; in the use process, the ethanol solution containing water enters the heat exchanger and the evaporator for treatment through the feeding assembly, is effectively vacuum filtered through a membrane filter, and then the product is cooled to below 35 DEG C in a product cooler and is sent to the inside of a product tank for finishing processing; the heat exchanger is arranged to improve the temperature of the feeding liquid through product heat exchange, thereby saving energy consumption.

This invention provides a 2-octanol recovery device for sebacic acid production, comprising a cracking reaction assembly, a high-level water tank, and a condensation recovery assembly. The cracking reaction assembly includes a cracking reactor and a feed tank. A gas emission pipe is located at the top of the cracking reactor, and the bottom of the reactor is connected to the feed tank via a discharge port. The condensation recovery assembly includes a condenser, a tail gas absorption tower, and a 2-octanol separation tank. A condensate inlet is located on one side of the condenser, and a water outlet is located at the top of the condenser. The water outlet is connected to the feed tank via a pipeline and also to a decolorization workshop via a pipeline. A water inlet and a condensate outlet are located at the bottom of the condenser. The water inlet is connected to the high-level water tank via a pipeline, and the condensate outlet is connected to the 2-octanol separation tank via a pipeline. This invention not only effectively recovers 2-octanol from high-temperature gas through the condenser but also converts the heat energy in the high-temperature gas into hot water for use in the next stage of production, thus achieving energy saving and consumption reduction.

Provided is a procedure for synthesizing an aqueous methanol solution from a mixed gas containing carbon dioxide and hydrogen under low-pressure conditions of less than 1 MPa. This method for synthesizing an aqueous methanol solution from a mixed gas containing hydrogen and CO2 is characterized by generating methanol and water vapor from a starting material gas containing CO2 and hydrogen by a catalytic reaction in a first reactor, then allowing 90% or more of both of the generated methanol and water vapor to permeate through to a membrane permeation side in a second reactor provided with a plurality of porous ceramic separation membranes that each have a separation layer including an MFI zeolite membrane body having a composition of Mn[AlnSi96-nO192] (2<n<8, M is a metal cation), and cooling and condensing the methanol and water vapor that have permeated through the membrane to obtain a 50 to 90 wt% aqueous methanol solution on the membrane permeation side.

This utility model relates to an MVR evaporation and concentration system for methanol-containing materials, including a material tank for storing materials, a feed pump for conveying materials, a material evaporation system for evaporating and concentrating materials, a water heater that uses secondary steam generated by the material evaporation system as a heat source to heat water and generate steam, a steam compressor for pressurizing and heating the steam generated by the water heater, a live steam source, a tail gas condenser, and a vacuum pump. This utility model uses the methanol-containing secondary steam generated during the evaporation process of methanol-containing materials as a heat source to heat water and generate pure steam. The pure steam enters the steam compressor and is compressed into high-pressure and high-temperature compressed steam. The compressed steam is used to evaporate and concentrate the methanol-containing materials. Live steam is only used as a supplementary heat source, which can effectively reduce the amount of live steam used, save costs, reduce the risk of methanol explosion, reduce the corrosion of the compressor's mechanical structure by methanol, and ensure the normal and stable operation of the system.