882results about "Hydroxy compound separation/purification" patented technology

The invention relates to the technical field of chemical engineering, in particular to a method and a device for removing heavy components from cyclohexanol. Comprising the following steps: a, rectifying a cyclohexanol-containing material from a cyclohexene hydration reaction to obtain a first solution containing cyclohexanol and heavy components in a tower kettle; b, carrying out heavy component removal operation on the first solution to obtain a third solution containing a catalyst and heavy components, a first gas phase and a second gas phase; and c, rectifying the first gas phase and the second gas phase to obtain a fourth solution subjected to heavy component removal, namely cyclohexanol subjected to heavy component removal. The entrained catalyst and heavy components are removed together, and the fluidity required by the catalyst waste liquid is maintained by using the heavy components, so that the loss of cyclohexanol is reduced.

The invention relates to the technical field of eutectic crystals, in particular to a lutein and mannitol eutectic crystal as well as a preparation method and application thereof, an XRD (X-Ray Diffraction) pattern of the eutectic crystal has characteristic diffraction peaks at least at positions where 2 theta angles are 9.71 degrees, 19.44 degrees, 20.4 degrees, 21.17 degrees, 22.07 degrees, 24.67 degrees, 25.32 degrees, 36.1 degrees, 40.39 degrees and 44.9 degrees, and error tolerance of + / -0.2 degrees exists; a characteristic endothermic peak exists at 163.7 DEG C in a DSC spectrum, and an error tolerance of + / -0.2 DEG C exists; the preparation method comprises the following steps: respectively dissolving mannitol and xanthophyll in water and absolute ethyl alcohol, mixing, carrying out high-temperature and high-pressure reaction, standing, crystallizing, filtering, spray-drying and grinding to obtain the eutectic crystal, and the eutectic crystal can be applied to cosmetics, health-care products, foods and medicines. The eutectic crystal provided by the invention has the advantage of good stability.

The invention relates to the field of biomass energy and chemical industry, in particular to an efficient methanol preparation method based on biomass graded catalytic conversion and cycle coupling. The method comprises the following steps: in a graded catalytic oxidation reaction system, mixing a biomass raw material with a composite vanadium-based catalyst, water, oxygen and circulating methanol for reaction to generate a gas-liquid mixture containing methyl formate; recycling methyl formate by using a gradient variable-pressure rectification separation system; carrying out an interface hydrogenation reaction under the action of a copper-zinc-LTA hierarchical pore catalyst to generate methanol; finally, part of methanol is purified and recycled through membrane separation. The method realizes efficient conversion from biomass to methanol, has the advantages of mild reaction conditions, low energy consumption, high yield and good catalyst stability, and opens up a new path for industrialization of preparation of methanol from biomass.

The invention relates to a lignin-based polymer pervaporation membrane, a preparation method thereof and a method for separating and purifying cyclohexane-KA oil. The invention aims to provide a pervaporation membrane which is high in permselectivity, high in stability and good in mechanical property. The pervaporation membrane is used for cyclohexane-KA oil separation and has the advantages of high separation efficiency, low energy consumption and simple process. The preparation method comprises the following steps: adding the surfactant, the polymer and the solvent into a reactor, and stirring at 50-70 DEG C for 4-6 hours to obtain a mixed solution; the method comprises the following steps: adding lignin and a solvent into a reactor, and stirring at room temperature for 4-6 hours to obtain a lignin solution; dropwise adding the lignin solution into the mixed solution, and continuously stirring at constant temperature for 12-24 hours to obtain a membrane casting solution; transferring the membrane casting solution to a centrifugal tube, performing centrifugal separation, and uniformly coating the membrane casting solution on an ultrafiltration membrane material with the membrane thickness of 100-200mm to form a uniform liquid membrane; and drying the liquid membrane to obtain the lignin-based polymer pervaporation membrane. Belongs to the technical field of membrane separation.

A gas separation method includes supplying a mixed gas to a zeolite membrane complex and permeating a high permeability gas through the zeolite membrane complex to separate the high permeability gas from other gases. The mixed gas includes a high permeability gas and a trace gas that is lower in concentration than the high permeability gas. The molar concentration of a first gas included in the trace gas in the mixed gas is higher than the molar concentration of a second gas included in the trace gas in the mixed gas. The adsorption equilibrium constant of the first gas on the zeolite membrane is less than 60 times that of the high permeability gas. The adsorption equilibrium constant of the second gas on the zeolite membrane is 400 times or more that of the high permeability gas.

The invention discloses a separation and preparation method of D-chiro-inositol, and relates to the technical field of D-chiro-inositol production, a D-chiro-inositol conversion liquid is subjected to thallus removal, deproteinization, desalination and concentration, then ethanol is added for primary separation, ethanol is added again for crystallization after dealcoholization, D-chiro-inositol is purified, and the D-chiro-inositol is obtained. The ethanol is an inert solvent, more chiral inositol in the solution can be crystallized by adding the ethanol, the yield is increased, after the ethanol is added, the viscosity of a crystallization system is reduced, the flowability of the system is better, the crystal can grow more uniformly during crystallization, the crystal is more uniform, and the purity of the product is improved. And the quality of the D-chiro-inositol is improved.

This invention discloses a system and method for producing methanol by carbon dioxide hydrogenation. The system includes a feedstock turbine compressor, a first feedstock gas heat exchanger, a second feedstock gas heat exchanger, an adiabatic reactor, an isothermal reactor, a gas-liquid membrane separator, and a molecular sieve. By setting up an isothermal reactor and utilizing the heat from the product produced by the adiabatic reactor in separate streams, heat coupling between the two reactors is achieved. The unreacted feedstock gas remaining after the adiabatic first-stage reaction is circulated in the isothermal reactor, reducing the size requirements of the adiabatic reactor and improving the overall conversion rate of carbon dioxide. This application solves the problems of high energy consumption in the distillation of by-product water in the carbon dioxide hydrogenation to methanol process, large investment in traditional equipment, serious heat loss, and excessive circulating gas volume in existing technologies.

According to the method, industrial-grade 1, 2-propylene glycol co-produced by a dimethyl carbonate process through a transesterification method is taken as a raw material, and purification processes of activated carbon adsorption impurity removal, deodorant impurity removal and rectification impurity removal are carried out, so that various indexes such as chromaticity, odor, purity and ultraviolet light transmittance of the obtained 1, 2-propylene glycol product reach the quality indexes of an imported pharmaceutical-grade 1, 2-propylene glycol product. According to the method disclosed by the invention, the pharmaceutical grade propylene glycol can be prepared with high quality, and a good development prospect and huge economic benefits are undoubtedly brought to the propylene glycol industry.

The invention relates to the technical field of glycerol purification, in particular to a high-purity glycerol deep purification process which comprises the following steps: adding methanol and phosphoric acid into crude glycerol to prepare pretreated glycerol; adding a composite alkali solution into the pretreated glycerol, standing and layering to obtain a clear liquid phase, adding activated carbon and stirring, and injecting filtrate into an ion exchange column after centrifugal separation; distilling the liquid flowing out of the ion exchange column to obtain semi-treated glycerol; and sequentially carrying out reduced pressure distillation and activated carbon deodorization and decolorization treatment on the semi-treated glycerol to obtain the high-purity glycerol. According to the method, methanol and phosphoric acid are firstly used for treatment, separation of glycerol is facilitated, salt is sufficiently separated out by adding a composite alkali solution, impurities in crude glycerol can be well adsorbed and removed by matching with added activated carbon, and non-electrolytic substances of the crude glycerol are adsorbed and fixed under the assistance of ion exchange resin, so that further purification is realized; finally, methanol and water are removed through distillation / reduced pressure distillation, and the purity of the obtained glycerol can reach 99.9%.

The invention discloses a production method of stable liquid aluminum isopropoxide, and belongs to the field of organic metal compound preparation. According to the method, an oxidation film on the surface of aluminum and water in isopropanol are removed through raw material pretreatment, and initial liquid aluminum isopropoxide is prepared in an inert atmosphere; the composite solvent is prepared by mixing a functional main solvent and a high-boiling-point auxiliary solvent in proportion, the addition amount of the composite solvent is 15-30% of that of the initial product, and the finished product is obtained through step-by-step stirring and mixing and precise filtration. Through double mechanisms of chemical coordination stabilization and physical volatilization inhibition, the problems of short shelf life and poor stability of the existing product are solved, the shelf life reaches 6-12 months, the purity is greater than or equal to 99.0%, the batch difference is less than or equal to + / -10%, and the preparation method has a good application prospect.

The utility model relates to an MTO (Methanol To Olefins) concentrated water treatment device, which comprises a circulating liquid phase hydrogenation unit and a dehydration unit, aldehyde and ketone components in MTO concentrated water are converted into mixed alcohol through circulating liquid phase hydrogenation, and most of water in the mixed alcohol is removed through flash evaporation degassing, azeotropic distillation and zeolite membrane dehydration treatment. According to the MTO concentrated water treatment device, a mixed alcohol product with low water content (about 2wt%) and waste water with low alcohol content (less than 0.2 wt%) are obtained, the technical index of the obtained mixed alcohol product is higher than the national standard of alcohol-based liquid fuel GB16663-1996, and ethanol, isopropanol and 2-butanol products can be obtained through further separation. The additional value is also improved, and the purposes of improving the quality and improving the efficiency are achieved.

The present invention provides a clofazimine ethanol crystalline compound, its preparation method, application, and pharmaceutical composition, relating to the field of biomedicine. The clofazimine ethanol crystalline compound provided by the present invention has a small size and a relatively large surface area. When used as a pharmaceutical, it has a high dissolution rate and a high in vivo absorption rate, enabling faster achievement of higher blood drug concentrations and providing enhanced therapeutic effects against diseases such as leprosy and drug-resistant tuberculosis.

The invention discloses a cadinane type sesquiterpene as well as a preparation method and application thereof. The cadinane type sesquiterpene is separated from cinnamon bark, and has at least one of structural formulas shown as a formula (I), a formula (II), a formula (III) and a formula (IV). Liver protection activity evaluation is carried out by applying an alcohol-induced hepatocyte injury model, and it is found that the cadinane type sesquiterpene can effectively relieve alcohol-induced AML-12 hepatocyte injury; the dumarane sesquiterpenes can inhibit the alcoholic liver disease and relieve fat accumulation, so that the dumarane sesquiterpenes have the anti-alcoholic liver disease activity, can be applied to preparation of the anti-alcoholic liver disease drugs, and have good research and development prospects; belongs to the field of natural medicinal chemistry.

The invention belongs to the technical field of chemical production, and particularly relates to a novel process for separating pentaerythritol by a membrane method and application of the novel process. The membrane separation comprises the steps of separating sodium formate by using an ion exchange membrane and separating pentaerythritol by using a low-pressure nanofiltration membrane device. The dealdehyding liquid is separated through different membranes, and formic acid, pentaerythritol, dipentaerythritol and other substances can be effectively separated. The process greatly shortens the process flow and saves the cost. According to the technical scheme, the quality and performance of the pentaerythritol product are remarkably improved, the added value of the product is increased, and a new technical scheme is provided for industrial production of pentaerythritol.

The invention relates to a separation and purification method of a high-carbon alcohol crude product. The method comprises the following steps: (a) washing a C11-C17 high-carbon alcohol crude product solution; (b) distilling the washed solution to remove heavy components; (c) mixing the de-heavy solution with an ionic liquid, adding a polar solvent into the mixture for extraction, and separating out inert components; and (d) distilling to remove light components in the high-carbon alcohol to obtain the high-carbon alcohol with the purity of more than 98.5 wt%. The method is mild in process, green in process and high in separation efficiency, product loss in the high-temperature cooking process is avoided, compared with a traditional high-carbon alcohol rectification process, energy consumption is lower, and the ionic liquid and the extraction agent can be recycled.

The invention relates to a device and a method for preparing isobutene and methanol by cracking methyl tert-butyl ether. The device comprises a methyl tert-butyl ether vaporization refining tower, a reactor, a cooling tower, an absorption tower, a methanol extraction tower, an isobutene light component removal tower and an isobutene heavy component removal tower which are sequentially connected along a material conveying direction, a top discharge hole of the cooling tower is connected with a lower gas-phase material inlet of the absorption tower; an absorbent outlet at the bottom of the absorption tower is circularly connected with a cooling absorption liquid inlet at the top of the cooling tower; the bottom extract liquor outlet of the methanol extraction tower is circularly connected with the top absorbent inlet of the absorption tower; an isobutylene discharge hole is formed in the top of the isobutylene heavy component removal tower; the device further comprises a methanol recovery tower and a methanol refining tower which are connected in sequence along the material conveying direction; a bottom cooling absorption liquid outlet of the cooling tower is connected with the methanol recovery tower; a methanol discharge hole is formed in the bottom of the methanol refining tower. The device provided by the invention not only can relax the limitation of the purity of methyl tert-butyl ether in raw materials, but also can prepare high-purity isobutene and high-purity methanol at the same time.

The invention belongs to the technical field of BDO recovery, and particularly relates to a process for recovering BDO from process waste liquid. The process comprises the following steps: S1, evaporation: evaporating the BDO process waste liquid and the BDO tower kettle residual liquid with higher BDO content generated in the step S2 in an evaporator to obtain BDO evaporated gas and BDO heavy component residual liquid; the operation pressure of the evaporator is 1-5 kPa, and the operation temperature is 150-190 DEG C; the BDO evaporation gas generated in the step S1 and the BDO light component residual liquid generated in the current step are rectified in a rectifying tower, BDO light component impurities are obtained at the tower top, part of the BDO light component impurities are condensed to form BDO light component residual liquid, the BDO light component residual liquid is returned to the rectifying tower, a BDO product is obtained on a side line of the rectifying tower, and BDO tower kettle residual liquid is obtained in a tower kettle; the operation pressure of the rectifying tower is 1-2kPa, the operation temperature of the tower top is 60-110 DEG C, and the operation temperature of the tower kettle is 140-180 DEG C. The method is coupled with an original BDO separation and purification process in a factory, and continuous and efficient recovery of BDO is realized by a short route under the condition that no extra organic solvent is introduced.

The invention discloses a reactor for preparing methanol through CO2 hydrogenation, a preparation system and a method thereof, and belongs to the technical field of methanol preparation, a mixed gas of carbon dioxide and hydrogen is introduced into a reaction assembly to react to obtain methanol and water, and the water is separated from the reaction assembly through a membrane separation assembly during the reaction. The membrane separation assembly is integrated in the reactor, generated water is moved out of the reactor during reaction, the reaction is pushed to be carried out in the forward direction, the one-way reaction conversion rate can be greatly improved, and therefore the efficiency of the reactor is greatly improved. Meanwhile, the circulating gas amount is reduced, and the energy consumption is reduced.

The invention discloses N-alkylated / sulfonated benzimidazole polyaryletherketone / polyaryletherketone sulfone with controllable grafting density as well as a preparation method and application of the N-alkylated / sulfonated benzimidazole polyaryletherketone / polyaryletherketone sulfone. The preparation method comprises the following steps: firstly, introducing a protecting group on a phenolic hydroxyl group of a bisphenol monomer containing a benzimidazole structure, then carrying out nucleophilic substitution reaction on alkyl halide / alkyl halide sulfonic acid and-NH, and then removing the protecting group to obtain an N-alkylated / sulfonated benzimidazole functionalized bisphenol monomer; copolymerizing the monomer, a bisphenol monomer and a difluoro monomer to obtain a polymer; alkyl or alkyl sulfonic acid is introduced to a benzimidazole ring, so that-NH bonds are passivated, a steric hindrance effect is formed, and gelation of the polymer under a high polymerization degree is avoided; by adjusting the molar ratio of the monomers, the retention stability of the functional groups can be effectively controlled, and compared with the traditional grafting on the polymer, the non-regulation of functionalization and the gelation of the polymer are effectively avoided.

This invention belongs to the technical field of medicinal chemistry, specifically relating to a novel crystal form of cariprazine, specifically the cariprazine-4-hydroxybenzoic acid-methanol-hemihydrate crystal form and its preparation method. The novel cariprazine-fumaric acid crystal form provided by this invention comprises a basic unit of one molecule of cariprazine, one molecule of 4-hydroxybenzoic acid, one molecule of methanol, and 0.5 molecules of water. Its preparation method is simple to operate, the crystallization process is easy to control, and it has good reproducibility. The formation of a eutectic significantly enhances the solubility of cariprazine, exhibiting strong pharmaceutical value.

This application discloses an integrated method and system for the co-production of MTO methanol and refined methanol, belonging to the field of chemical technology. The co-production method provided by this application includes: feeding crude methanol into a light-duty removal distillation column for pre-distillation treatment to obtain a pre-distillation column bottom component; dividing the pre-distillation column bottom component into two streams, one as the output of MTO methanol and the other as a reprocessed component of the pre-distillation column bottom; feeding the reprocessed component of the pre-distillation column bottom into a refined methanol distillation column for distillation treatment to obtain a distillation column top component and a distillation column bottom component; at least a portion of the distillation column top component is output as refined methanol, and the distillation column bottom component is returned to the light-duty removal distillation column. This application achieves the co-production of refined methanol using only two columns, eliminating the need for additional independent equipment, significantly reducing equipment investment costs, and enabling flexible adjustment of both MTO methanol and refined methanol products, thus possessing broad application prospects in the industrial-grade MTO methanol field.

The present invention provides a method for concentrating an ethylene glycol aqueous solution, comprising the following steps: S1, modifying a cationic resin with metal ions to obtain a modified cationic resin; S2, passing the ethylene glycol aqueous solution and excess butyraldehyde through a packed tower filled with the modified cationic resin to react for a period of time; wherein the butyraldehyde serves as both a reactant and an extractant; S3, after the reaction period, performing static separation, hydrolyzing the extract phase at a certain temperature using the modified cationic resin as a catalyst, and then recovering the butyraldehyde by distillation to obtain a concentrated ethylene glycol aqueous solution. The present invention has the advantages of low energy consumption and no wastewater.

The present disclosure provides compositions and methods of recovering a policosanol or a sterol from a mixture comprising one or more fatty alcohols, aldehydes, fatty acids, and / or sterols. The mixture may be, for example, a lipid extract obtained from industrial fermentation processes (e.g., filter cake, distillate residue). The policosanol and / or sterol fraction recovered may be enriched in certain fatty alcohols (e.g., 1-octacosanol, 1-triacontanol, and / or 1-dotriacontanol), or enriched in certain sterols (e.g., ergosterol, campesterol, stigmasterol, and / or β-sitosterol). These bioactive molecules may be useful in the treatment or prevention of various metabolic conditions (e.g., obesity, dyslipidemia, cardiovascular conditions, and other chronic metabolic diseases).

The application belongs to the technical field of microorganisms and particularly relates to a kind of Aspergillus ustus and application thereof.The Aspergillus ustus is preserved in China General Microbiological Culture Collection Center, and the preservation number is CGMCC No.40820.The Aspergillus ustus can be separated to obtain sesquiterpenes shown in formula I and formula II, and the sesquiterpenes have good bacteriostatic activity on Physarum polycephalum, and the bacteriostatic rates are 79.45% and 76.71% respectively at a final concentration of 100 μg / mL, which is equivalent to the control agent of bercyn in inhibiting mycelial growth.

The invention provides a 1, 4-butynediol membrane separation recovery and waste catalyst treatment device and a method thereof, and relates to the technical field of chemical process separation. Comprising a 1, 4-butynediol membrane separation and extraction device, a clear liquid backwashing device, a waste catalyst treatment device and a purified water washing and backwashing slag discharging device, one end of the 1, 4-butynediol membrane separation and extraction device is connected with the reactor, and the other end of the 1, 4-butynediol membrane separation and extraction device is connected with a clear liquid pipeline and a waste catalyst collection tank; one end of the clear liquid backwashing device is connected with a clear liquid pipeline, and the other end of the clear liquid backwashing device is connected with the 1, 4-butynediol membrane separation and extraction device; one end of the waste catalyst treatment device is connected with the waste catalyst collecting tank and the washing device, the other end of the waste catalyst treatment device is connected with a clear liquid pipeline, and the waste catalyst treatment device collects and washes waste catalysts through a waste residue pipeline. The 1, 4-butynediol membrane separation recovery and waste catalyst treatment method comprises the application method of the device, and the method provided by the invention is higher in 1, 4-butynediol recovery ratio, higher in operation flexibility, high in product recovery rate in the waste catalyst, and safe and environment-friendly in waste catalyst treatment.

The application relates to a preparation method and application of a silicone / MOF-303 mixed matrix membrane. A silicon source precursor is uniformly dissolved in an ethanol solvent, a mixture of water and hydrochloric acid is added in a certain proportion, water bath heating is carried out for a period of time, and a silicone sol is obtained. MOF-303 powder prepared in advance is added into the silicone sol in a certain proportion, ultrasonic mixing is carried out to obtain a separation layer sol, the prepared separation layer sol is coated on a ceramic support through a hot coating method, and calcination is carried out in an air atmosphere for a period of time to obtain a MOF-303 / mixed matrix membrane. The application preferably uses an organic silicone substance BTESA with a rigid acetylene bridge structure as a precursor, and the MOF-303 material with a high specific surface area is doped into the precursor, the pore structure of the membrane is modified, and more adsorption sites are provided for water molecules. Through optimization of the composite proportion, a composite membrane material with the best separation performance is obtained.

The utility model relates to the technical field of alcohol extraction, in particular to a secondary alcohol cooling and extracting system which comprises an evaporating tank and a collecting tank, the evaporating tank is connected with the collecting tank through a cooling and extracting device, the cooling and extracting device comprises a condenser, and the condenser is fixedly connected to the top of the evaporating tank through a supporting component; wherein the supporting component comprises a first supporting part and a second supporting part, and the first supporting part and the second supporting part are used in a telescopic mode through an adjusting assembly; a fixing assembly is arranged on the top of the second supporting part and used for fixing the condenser, the condenser can be conveniently adjusted and installed through an adjusting assembly, the condenser is limited and supported through an annular part, then a connecting belt is pulled to abut against the condenser, and after the connecting belt and a clamping rod are fixed, the effect of conveniently installing the condenser is achieved. The condenser is convenient to disassemble and assemble, and meanwhile the downtime can be effectively shortened.

The invention discloses a treatment technology for separating a sorbic acid isomerization product, and belongs to the field of chemical engineering. According to the method, water and ethanol in the eliminated mother liquor are separated through selective separation of the dehydration membrane, so that an ethanol solution with higher concentration is obtained, the concentrations of sorbic acid and isomers in the solution are increased, then the crystallization temperature is controlled by utilizing the solubility difference of the sorbic acid and the isomers in the alcohol, and the crystallization efficiency is improved. Sorbic acid containing a low isomerization product is separated and recovered, so that the quality of a finished product is effectively improved.

This invention relates to the field of separation and purification technology, and discloses a method and system for preparing ultra-clean, high-purity isopropanol. The method includes: isopropanol feedstock undergoing a first distillation and a first adsorption process; the first distillation removes light organic components and water, and the first adsorption removes organic impurities including water, alcohols, ethers, and ketones; the first adsorption is performed before or after the first distillation; followed by a second distillation and a second adsorption process; the second distillation removes heavy organic components and most of the metal cations and anions, and the second adsorption further removes metal cations and anions; the second adsorption is performed before or after the second distillation; followed by a third distillation to further remove water, alcohols, ethers, ketones, organic impurities, metal cations, and anions; and finally, filtration to obtain ultra-clean, high-purity isopropanol. This method can obtain ultra-clean, high-purity isopropanol products with low water content and low levels of alcohol, ketone, and ether impurities.