188 results about "Simulated moving bed" patented technology

The invention discloses a method for continuously and efficiently adsorbing and separating hydrogen isotopes. The hydrogen isotopes are separated by adopting a multi-tower variable-temperature variable-pressure device operated in a simulated moving bed operation mode. When the device runs, each adsorption tower needs to sequentially execute the following steps: 1, adsorption; 2, replacement; 3, heating; 4, vacuumizing and desorbing; 5, carrying out vacuum purging; 6, pressurizing and cooling; the operation mode of the simulated moving bed is that an adsorption tower is frequently, sequentially and synchronously moved along the gas flowing direction in the tower through all gas input and output ports, so that an adsorbent phase and a gas flowing phase in the tower form countercurrent flow, and the hydrogen isotope adsorption separation efficiency is enhanced. The invention relates to a technological process of cyclic adsorption, replacement, heating, vacuum desorption, pressurization and cooling, continuous and efficient hydrogen and isotope adsorption separation is realized, multi-tower serial adsorption and replacement are adopted in the process, and separation of hydrogen isotopes (such as H2 / D2) is enhanced; and the desorption efficiency of heavy components is improved by adopting a heating and vacuumizing depressurization coupling mode.

The invention discloses a method for preparing cellobiose and comprehensively utilizing a by-product of cellobiose. The method is characterized by specifically comprising the following steps: (1) dilution, (2) enzymolysis, (3) flocculation and carbon explosion, (4) decoloration, (5) continuous ion exchange, (6) evaporation and concentration, (7) simulated moving bed chromatographic separation, (8) concentration, (9) finished product preparation and (10) raffinate utilization. The method effectively solves the problems of low preparation purity and high production cost of cellobiose.

The invention provides a synthetic method of high-purity p-methylstyrene. The method comprises the following steps: carrying out alkylation on toluene and catalytic dry gas in a modified ZSM-5 catalyst to generate methyl-ethylbenzene, carrying out adsorption separation on the methyl-ethylbenzene to obtain high-purity p-methyl-ethylbenzene, and carrying out high-temperature dehydrogenation on the p-methyl-ethylbenzene in the presence of an iron-based catalyst to obtain the high-purity p-methyl styrene. According to the method, based on the synergistic effect of a preparation process and an alkylation reaction catalyst, the para-selectivity of the alkylation reaction catalyst is strictly controlled, so that the selectivity of the catalyst is ensured, the service life of the catalyst is greatly prolonged, and furthermore, a simulated moving bed is utilized to adsorb and separate methyl ethylbenzene isomers, separate, purify and recycle; the raw material utilization rate and the product purity are improved, and the purity of the finally obtained p-methylstyrene is 99% or above.

The invention relates to the technical field of biology, and particularly discloses a method for removing lactulose-based isomers in an oligosaccharide separation and purification process. The method comprises the following steps: taking oligosaccharide fermentation liquor for producing oligosaccharide through fermentation by using lactose as a substrate, sequentially carrying out thallus removal, decoloration, electrodialysis desalination, ion exchange resin desalination, concentration, sequential simulated moving bed chromatographic purification, ultrafiltration, re-concentration and spray drying, and detecting the oligosaccharide and the lactulose-based isomer in the oligosaccharide. According to the method disclosed by the invention, the content of lactulose-based isomers in the separation and purification process is greatly reduced, so that the product purity is effectively improved; the method can be applied to the synthesis process of other milk oligosaccharides such as fucose lactose (FL), lactose-N-tetraose (LNT), lactose-N-neotetraose (LNnT), lactose-N-fucopentasaccharide (LNPFI) and the like or other carbohydrates containing a lactosyl group, has a very high application value, and accords with laws and regulations.

The invention discloses a method for efficiently preparing chlorogenic acid by using a stevia rebaudiana extracting solution, which comprises the following steps: concentrating the stevia rebaudiana extracting solution, and adjusting the pH value of the concentrated solution to 5.0-6.5 to obtain a to-be-treated solution; pumping the to-be-treated liquid into a simulated moving bed chromatographic system for separation to obtain a chlorogenic acid phase and a stevioside phase; adjusting the pH value of the chlorogenic acid phase to 3.0-4.5, then sequentially carrying out nanofiltration membrane concentration and thermal concentration, and finally carrying out spray drying to obtain a chlorogenic acid product. According to the method, ethanol extraction, simulated moving bed separation and nanofiltration membrane desalination are combined, the yield of the prepared chlorogenic acid is high, the extraction efficiency is high, the technological process is simple, and the production cost is low. In addition, stevioside is also recycled in the process of preparing the chlorogenic acid.

The invention provides a method for separating and purifying galactose and glucose by using a simulated moving bed chromatography system, and relates to the technical field of saccharide separation and purification. According to the method, the simulated moving bed chromatography system is used for separating and purifying the galactose, operation can be carried out under the set temperature condition, the separation and purification efficiency of the galactose is remarkably improved, continuous large-scale efficient separation and purification of the galactose can be achieved, the separation and purification effect is good, the yield is high, and the product quality is good. According to the method, pure water is used as an eluent, and analyzed and purified compounds are free of damage, low in toxicity, rich in source and low in cost.

The invention provides a method for separating and purifying ergothioneine by simulated moving bed chromatography, which comprises the following steps: step 1, carrying out pretreatment, sterilization and ultrafiltration on fermentation liquor to obtain ultrafiltrate; 2, separating and purifying the ultrafiltrate by adopting a simulated moving bed chromatography system, and collecting a target component containing ergothioneine; and step 3, carrying out deep desalination, decoloration, concentration, cooling crystallization, centrifugation and drying on the target component to obtain a pure ergothioneine product. According to the method for separating and purifying the ergothioneine through the simulated moving bed chromatography, in the ergothioneine preparation process, the ergothioneine is purified from fermentation liquor through the simulated moving bed technology, and the method is high in efficiency and capable of achieving automatic and continuous large-scale production.

The invention relates to the technical field of biology, in particular to a method for purifying 6-sialic acid lactose. According to the 6-sialic acid lactase reaction liquid prepared based on multi-enzyme catalysis, the high-efficiency, high-purity and high-recovery-rate purification method of the 6-sialic acid lactase is developed by combining membrane separation and simulated moving bed chromatography technologies, meanwhile, less wastewater is generated, the cost benefit is high, and continuous large-scale production can be achieved.

Systems and methods are provided for multiplexed extraction of target minerals from a variety of separate or combined desalination brines and / or wastewater sources. The use of multiple pretreatment, extraction, and posttreatment apparatuses with intelligent, directed flow control can allow for a single system to extract multiple target minerals. Improved extraction methods including zwitterionic simulated moving bed chromatography with target-specific zwitterions can allow for improved extraction efficiency and recovery rates with a dramatically reduced environmental footprint compared to existing methods.

Systems and methods are provided for multiplexed extraction of target minerals from a variety of separate or combined desalination brines and / or wastewater sources. The use of multiple pretreatment, extraction, and posttreatment apparatuses with intelligent, directed flow control can allow for a single system to extract multiple target minerals. Improved extraction methods including zwitterionic simulated moving bed chromatography with target-specific zwitterions can allow for improved extraction efficiency and recovery rates with a dramatically reduced environmental footprint compared to existing methods.

A method for separating and purifying 4MP1 from a mixture containing 4MTP2 and 1-Hexene comprises the following steps: continuously introducing a solution in which 4MTP2, 1-Hexene and 4MP1 with any concentration are dissolved into a simulated moving bed chromatography system as a raw material solution, collecting a high-purity 4MP1 solution from raffinate of the simulated moving bed chromatography system by adopting a metal organic framework material as a stationary phase, and separating the high-purity 4MP1 solution from the raffinate of the simulated moving bed chromatography system. The extraction liquid is a solution containing impurities 4MTP2 and 1-Hexene. The invention provides a brand new method for separating 4MP1 from 4MTP2 and 1-Hexene, and a complete separation scheme is provided for the prior art; in the separation of high-concentration 4MP1, the relative purity of the separated and purified 4MP1 can reach gt; the recovery rate is gt; and in the separation of low-concentration 4MP1, the rectification level is also exceeded, and the method is more suitable for 4MP1 thermosensitive substances.

A continuous chromatography system includes a plurality of treatment columns, each column of the plurality of columns including an adsorbent. The system further includes a valve system configured to operate the plurality of columns as a simulated moving bed system. The valve system includes a first valve configuration having an injection of a brine into a first column of the plurality of columns and an extraction of an eluate from a second column of the plurality of columns. The second column being a different column than the first column. The valve system further includes a second valve configuration comprising a recirculation of fluid through the plurality of columns.

The utility model relates to online elution equipment for a simulated moving bed. The online elution equipment comprises an adsorption system, a replacement system, a raw material feeding system, a mobile phase feeding system, a circulating system, a raffinate system and an extract system, the adsorption system comprises a plurality of adsorption columns, and each functional area is provided with at least one adsorption column; the replacement system comprises a replacement column and a replacement pipeline assembly, the structure of the replacement column is the same as that of the adsorption column, and the column top and the column bottom of the replacement column are connected with the column top and the column bottom of each adsorption column through the replacement pipeline assembly; the replacement column can replace the adsorption column in the isolation area so as to elute the adsorption column in the isolation area. Therefore, after the adsorption column in the isolation area is replaced by the replacement column, the replacement column can be connected into the circulation loop, so that the whole equipment can normally operate, the adsorption column in the isolation area does not need to be shut down during elution, and the stable and uninterrupted operation of the equipment is ensured.

The utility model relates to the technical field of simulated moving beds, and discloses a collection distributor for simulated moving bed purification and separation equipment, which comprises a distribution transverse pipe, the upper end of the distribution transverse pipe is fixedly connected with a main pipe, and the upper end of the main pipe is provided with an insertion pipe. The collection distributor for the purification and separation equipment of the simulated moving bed is provided with a first sliding rod, a first screw rod and a first adjusting seat, when a support and the simulated moving bed are fixedly installed and a main pipe needs to transversely align a pipeline of the simulated moving bed, two first motors are started to rotate forwards and backwards respectively, the two first screw rods are driven to rotate, and the first adjusting seat and the second adjusting seat are adjusted. The two first adjusting seats in threaded connection are driven to move along the first sliding rods, so that the main pipe is aligned with the pipeline of the simulated moving bed in the transverse direction, the collecting distributor can be fixedly installed with the simulated moving bed after roughly aligning, the multiple motors are started to finely adjust the main pipe, and the main pipe and the pipeline of the simulated moving bed are assisted to be fixedly installed. Manpower is saved, and the mounting efficiency is improved.

The invention concerns a process for the separation of carbon monoxide (CO) from a feed comprising CO and nitrogen (N2), wherein the process is carried out in a simulated moving bed (SMB) system. The invention furthermore concerns an SMB system for the separation of carbon monoxide (CO) from a feed comprising CO and nitrogen (N2) comprising serially connected adsorption columns each comprising a CO adsorbent.

The present invention discloses a method for preparing fuel ethanol from straw biomass and the fuel ethanol, belonging to the technical field of fuel ethanol production. It includes: dissolving and hydrolyzing straw and concentrated sulfuric acid to obtain a saccharified solution, separating out a sugar-rich solution in a simulated moving bed chromatography system, and then mixing it with Saccharomyces cerevisiae SEB3 for fermentation, and generating fuel ethanol through distillation. The method for preparing fuel ethanol from straw biomass provided by the present invention can obtain fermentable sugars under normal pressure and low temperature conditions by using concentrated acid hydrolysis, and has the remarkable advantages of low energy consumption, low toxic by-products, and no need to input cellulase. And Saccharomyces cerevisiae SEB3 is used for fermentation. This strain has the ability of co-fermenting all sugars, can realize the fermentation of all sugars, synchronously convert all sugars into ethanol, the sugar consumption efficiency reaches more than 90%, and the ethanol recovery rate reaches more than 80%, and it is applicable to industrial production.

The invention discloses a method for preparing galacto-oligosaccharides, comprising the following steps: S1, using a lactose solution as a raw material, loading a barrier layer with beta-galactosidase immobilized by calcium pectin gel-chitosan, wherein the calcium pectin gel-chitosan as a carrier is composed as follows: chitosan is assembled on the surface of calcium pectin gel particles by electrostatic adsorption, and the beta-galactosidase is cross-linked to the chitosan; S2, circulating, wherein the lactose solution flows through the surface of the calcium pectin gel-chitosan and contacts with the beta-galactosidase for reaction; S3, pumping out the reaction solution, separating the galacto-oligosaccharides using a continuous simulated moving bed technology, and recovering the separated lactose to continue the reaction; the invention uses the calcium pectin gel particles as the core, gathers chitosan on the surface of the gel particles, further adsorbs and cross-links the beta-galactosidase, and cooperates with the liquid circulation during the reaction process to effectively improve the conversion rate of the galacto-oligosaccharides.

This invention relates to a method for the liquid-phase adsorption separation and purification of 2,3-dichloronitrobenzene and 3,4-dichloronitrobenzene, belonging to the field of chemical separation. This method for the simultaneous separation and purification of 2,3-dichloronitrobenzene and 3,4-dichloronitrobenzene involves preparing small spherical molecular sieve adsorbents from USY molecular sieves, silicon coupling agent-modified illite, and biomass polysaccharides, which are then loaded into a countercurrent simulated moving bed for separation and purification. This method can simultaneously obtain 2,3-dichloronitrobenzene and 3,4-dichloronitrobenzene with a purity ≥99%. The separation and purification method adopted in this invention is not only energy-efficient and highly effective, but also enables continuous production of two high-purity dichloronitrobenzenes, possessing significant industrial application value.

The present invention relates to a method for extracting glutamic acid using a sequential simulated moving bed, comprising the following steps: (1) screening an adsorption resin suitable for separating glutamic acid and glucose; (2) determining single column parameters, and determining adsorption isotherm parameters and kinetic parameters; (3) obtaining operating parameters through multi-objective optimization; and (4) performing a sequential simulated moving bed experiment based on the optimized operating parameters. The present invention introduces simulated moving bed technology into an amino acid system, performs separation operations by regulating specific variables in a simulated moving bed, uses a genetic algorithm multi-objective optimization method to explore conditions, takes the final performance of the product as a direct target, uses Fortran programming to perform process simulation, performs operating condition screening and simulates the moving bed experiment design, so that the entire separation process is faster and more efficient, and the process flow is simplified.

The invention discloses a preparation method of galactooligosaccharide, which comprises the following steps: S1, taking a lactose solution as a raw material, loading beta-galactosidase immobilized by calcium pectate gel-chitosan in an interlayer, wherein the composition mode of the calcium pectin gel-chitosan serving as the carrier is as follows: the chitosan is assembled on the surfaces of calcium pectin gel particles through electrostatic adsorption, and the beta-galactosidase is cross-linked to the chitosan; s2, circulation is carried out; a lactose solution flows through the surface of the calcium pectate gel-chitosan and is subjected to a contact reaction with beta-galactosidase; s3, pumping out the reaction liquid, separating by using a continuous simulated moving bed technology to obtain galactooligosaccharide, and recovering separated lactose to continue the reaction; the calcium pectin gel particles are used as cores, chitosan is gathered on the surfaces of the gel particles, beta-galactosidase is further adsorbed and crosslinked, and liquid circulation in the reaction process is matched, so that the conversion rate of galactooligosaccharide is effectively increased.

The present invention discloses a process for separating sugar and acid using an eight-zone simulated moving bed. The eight-zone simulated moving bed system is composed of 16 chromatographic columns filled with H-type cation exchange resins, and every two columns form a zone with a total of eight zones, specifically separation zones (Zones II, III, VI, and VII), stationary phase regeneration zones (Zones I and V), and eluent regeneration zones (Zones IV and VIII). The mobile phase direction of the entire system is opposite to the column switching direction, and the flow rate is controlled by three inlets and three outlets to achieve continuous separation of three components (sulfuric acid, monosaccharides, and organic acids). The technical solution of the present invention can achieve a recovery rate of sulfuric acid and xylose higher than 98%, a mass purity of xylose and sulfuric acid higher than 99%, and a solvent consumption of only 0.09 mL of deionized water per 1 g of xylose produced.

Systems and methods for recycling polymers. A method for recycling synthetic polymers by combining the polymers with a solid depolymerizing catalyst in a vessel, mechanically shearing the combined polymers and the solid depolymerizing catalyst against each other to produce monomers from the polymers; and collecting the monomers. The solid depolymerizing catalyst can be solid sodium hydroxide. Collecting the monomers can be achieved by contacting the sheared polymer and catalyst with a recyclable volatile solvent to dissolve the monomers. The method can include purifying the collected monomers for repolymerization. Purifying the monomers can be achieved using nanofiltration membrane technology, cyclic fixed bed adsorption, simulated moving-bed adsorption or a combination thereof.

The invention discloses equipment and a method for dry flue gas desulfurization based on a simulated moving bed, an adsorption tower and a regeneration double-tower process of traditional dry flue gas desulfurization are combined into a single module unit adsorption regeneration tower process, the tower is composed of a plurality of module units with the same function, and the module units are similar in structure, are arranged in parallel and are mutually independent. And a program control valve group is adopted for orderly switching the working process, so that efficient coupling among the multi-module units, the heating medium circulating system, the refrigerant circulating system and the carrier gas injection system in the tower is realized, and a continuously matched adsorption regeneration process among the multi-module units is realized. The process trend of a gas phase is periodically changed through a program control valve group, meanwhile, an adsorbent is kept still in situ, the effect of simulating a moving bed by a fixed bed is achieved, the solid adsorbent in the whole process is free of dynamic transfer and abrasion, the fixed bed can keep a good filling state, the gas phase is uniformly distributed in a bed layer, and the product quality is stable; and large handling capacity and automatic operation can be conveniently realized.

The utility model discloses a treatment device for scutellaria baicalensis acidification waste liquid. The treatment device comprises a pretreatment tank, a ceramic membrane filter, a first nanofiltration membrane filter, a first buffer tank and a simulated moving bed chromatographic separation system, an organic salt phase outlet of the simulated moving bed chromatographic separation system is communicated with a second buffer tank, a second nanofiltration membrane filter, a first heat concentration tank, a first spray dryer and a scutellaria baicalensis flavone storage tank; an organic phase outlet of the simulated moving bed chromatographic separation system is communicated with a first reverse osmosis membrane filter, a second heat concentration tank, a second spray dryer and a scutellaria baicalensis polysaccharide storage tank; permeate outlets of the first nanofiltration membrane filter and the second nanofiltration membrane filter are communicated with a second reverse osmosis membrane filter; the second reverse osmosis membrane filter is communicated with a third thermal concentration tank, a cooling tank, a plate and frame filter, a drying tank and a potassium chloride storage tank. According to the device, effective components in the scutellaria baicalensis acid precipitation waste liquid are effectively separated, the economic value of the scutellaria baicalensis acid precipitation waste liquid is improved, and environmental pollution caused by direct emission of the scutellaria baicalensis acid precipitation waste liquid is avoided.

Process and device for simulated moving bed extraction of lithium by adsorption, in which at least one column (Ci) is supplied with a feed (F) comprising lithium and a desorbent (D), and an extract (E) and a raffinate (R) are withdrawn from the column. The column comprises an adsorbent solid (Ai) and is configured to operate in a closed loop. The supply and withdrawal points of the column are shifted over time by a value corresponding to a predetermined quantity of adsorbent solid with a permutation period and determine a plurality of operating zones of the column, in particular the following main zones: a lithium desorption zone I; a desorption zone II of compounds other than lithium; and a lithium adsorption zone III. According to the invention, a portion of the extract is recycled to the feed.

Provided is an assembly comprising: at least one valve box block (20) comprising a plurality of valves (25) controllable via a control surface (24) of the valve box block (20); a valve control block (10) having an operating surface (11), the valve control block (10) being configured to control each of the plurality of valves (25) when the operating surface (11) contacts the control surface (24) of the at least one valve box block (20), the valve control block (10) comprising at least one sliding groove (14) formed in the operating surface (11); and at least one sliding member (30) configured to contact the at least one sliding groove (14). 4) slidably interlocked so that at least one sliding component (30) is movable relative to the valve control block (10) in a sliding direction parallel to the operating surface (11); at least one traction bracket (40, 50) is configured to surround at least one valve box block (20) and interact with at least one sliding component (30) so that sliding movement of at least one sliding component (30) in at least one sliding groove (14) causes the traction bracket (40, 50) to traction the at least one valve box block (20), wherein its control surface (24) abuts against the operating surface (11) of the valve control block (10).

The invention relates to a process for the preparation of an allulose product comprising enzymatic conversion of fructose into allulose; chromatographically separating the thus obtained crude product into (i) one or more allulose enriched fractions, (ii) a fructose enriched fraction, and optionally (iii) a purge fraction, preferably by simulated moving bed chromatography; and recirculating the fructose enriched fraction to the enzymatic conversion.

The invention relates to a method for purifying a plastic feedstock to obtain a purified polymer stream, comprising: a) a dissolution step in which the plastic feedstock is brought into contact with a dissolution solvent; followed by b) an extraction step by means of size exclusion, in which beds of size exclusion solids are used in series, the polymer solution from a) is fed at an injection point (F) and an eluent is fed at an injection point (S), and the extract is removed at a removal point (E) and a raffinate comprising the purified polymer solution is removed at a removal point (R), the injection point and the extraction point are separated and are moved by one bed along with time according to a given frequency; followed by c) a polymer-solvent separation step to obtain a stream of purified polymer. The invention also relates to a device for carrying out step b) and to a device for carrying out said purification method.

The application discloses a method for separating spirodiphenol by using an analog moving bed chromatography. The method for separating spirodiphenol specifically disclosed comprises the following steps: separating left-handed spirodiphenol and right-handed spirodiphenol from a spirodiphenol racemate by using an analog moving bed chromatography system; and the analog moving bed chromatography system has the following conditions: a stationary phase: silica gel coated with chiral polymer; and a mobile phase: a mixed solution of n-hexane and ethanol. The application can realize complete separation of two single enantiomers, obtain high purity and high recovery rate, and is more suitable for industrial production while being continuously operated. The process has strong stability, constant product quality, high automation degree, higher yield and lower cost than batch chromatography. The method also has the advantages of high yield, low cost, recyclable elution phase, green environmental protection, automatic and continuous production, stable product quality and the like.

A method for separating aromatic hydrocarbon components and non-aromatic hydrocarbon components in fuel oil by using a simulated moving bed. The method comprises the following steps: introducing fuel oil into a simulated moving bed so that the fuel oil is in contact with an adsorbent in the simulated moving bed and aromatic hydrocarbon components in the fuel oil are selectively adsorbed by the adsorbent, thereby obtaining a raffinate rich in non-aromatic hydrocarbon components; and introducing a desorbent into the simulated moving bed to desorb the adsorbed aromatic hydrocarbon components from the adsorbent, thereby obtaining an extract rich in aromatic components, wherein the desorbent comprises an alkane mixture and aromatic hydrocarbons, and the alkane mixture comprises cycloalkanes and linear alkanes. The method can significantly reduce the concentration of the aromatic hydrocarbon desorbent left in an adsorption area, improve the utilization efficiency of the adsorbent, and thus improve the aromatic hydrocarbon content in the extract, reduce the aromatic hydrocarbon content in the raffinate and further improve the aromatic hydrocarbon yield.