1198 results about "Melanin" patented technology

The invention discloses bacillus velezensis as well as fermentation product filtrate and a biological product thereof, and belongs to the technical field of microorganisms, a bacillus velezensis BTN-HB-F4 strain is separated and purified from prinsepia utilis royle in Harba snow mountain in Yunnan province, the fermentation product filtrate of the bacillus velezensis has excellent HAS inhibition capacity and remarkable DPPH and ABTS free radical scavenging capacity, and the biological product of the bacillus velezensis has the advantages that the biological product can be used for preparing biological products of the prinsepia utilis royle; a good anti-oxidation effect can be realized; secondly, under various concentrations, fermentation product filtrate can remarkably reduce the proportion of SA-beta-Gal positive cells, gene expression of matrix metalloproteinase 3 can be remarkably inhibited, and a good anti-aging effect is achieved; in addition, fermentation product filtrate can remarkably inhibit generation of zebra fish melanin and has a good whitening effect; the secretion amount of cell inflammatory factors IL-6 and TNF-alpha can be remarkably inhibited, and a good relieving effect is achieved; finally, the fermentation product filtrate can effectively inhibit the growth of pathogenic bacteria staphylococcus aureus, and has the potential of regulating the skin micro-ecology.

The invention provides application of UBR5 in preparation of drugs for treating pigmented skin diseases, and further the pigmented skin diseases comprise various types of pigmented nevus (mainly congenital pigmented nevus and megalous with the risk of malignant transformation). Various pigmented spots (mainly chloasma, freckles, Taitian nevus, post-inflammation hyperpigmentation and the like) and hypopigmentation / depigmentation spots (mainly leucoderma, post-inflammation hypopigmentation and the like). Experimental results show that UBR5 is highly expressed in disease tissues such as pigmented nevus. The UBR5 expression level and the melanogenesis ability are in significant positive correlation, targeted knockout / knockdown of UBR5 in melanocytes can significantly inhibit the expression level of melanogenesis related genes such as MITF, TRP1, TRP2, TYR and other proteins, the melanin content of melanocytes and tyrosinase activity, vice versa, and the melanogenesis ability of melanocytes after overexpression of UBR5 is significantly increased.

The invention relates to the technical field of genetic engineering, and particularly discloses a genetic engineering bacterium for producing melanin as well as a construction method and application of the genetic engineering bacterium. According to the application, the yield of the melanin can be effectively increased by modifying a metabolic pathway of the genetically engineered bacterium, and the yield of the melanin reaches 6.2 g / L and 18.5 g / L respectively through shake-flask culture and 5L fermentation tank culture. Compared with the prior art, the yield of melanin produced by the genetically engineered bacterium is improved by 30% at the shake flask fermentation level, the fermentation yield of a fermentation tank is improved by 4.3 times, in addition, expensive tyrosine is changed into glucose as a fermentation precursor substance, the production cost is greatly reduced, and an efficient and feasible solution is provided for large-scale production of melanin.

Provided are a whitening and freckle-removing composition, a gel, a preparation method therefor, and a use thereof, relating to the technical field of skin-care products. The whitening and freckle-removing composition comprises tranexamic acid, nicotinamide, 4-butylresorcinol, licorice extract, 3-o-ethyl ascorbic acid, and glutathione. For the whitening composition, by inhibiting the activity of tyrosinase, blocking the transfer of melanin from melanocytes to keratinocytes, and inhibiting the formation and accumulation of melanin by means of multiple mechanisms including oxidation resistance, and by means of the synergistic action of all components, cosmetic benefits of whitening and freckle-removing are achieved. The whitening and freckle-removing gel has a simple preparation method, has a mild and non-sensitizing formula, is safe and non-irritating, and is suitable for large-scale production and application.

The invention belongs to the technical field of biological dyes, and discloses a bio-based melanin precursor compound, bio-based melanin as well as a preparation method and application of the bio-based melanin precursor compound and the bio-based melanin. The invention provides a bio-based melanin precursor compound 4-[5-(2, 2-diaminoethyl)-2, 3-dihydroxyphenyl]-1H-indole-5, 6-diphenol, and a preparation method of the bio-based melanin precursor compound. The bio-based melanin precursor compound is stable in chemical property and easy to store. And the catalyst can be used as a raw material to efficiently synthesize bio-based melanin through a catalytic oxidation reaction. The process for preparing the bio-based melanin is simple, mild, high in yield and suitable for large-scale industrial production. The bio-based melanin prepared by the invention has good application performance during dyeing, does not generate harmful substances, and is safe and environment-friendly.

The invention discloses a multi-effect repair type collagen and application thereof, and belongs to the technical field of synthetic biology. Transdermal peptide TD-1, a transmembrane region of human XVII type collagen, an extracellular sixteenth non-collagen region, an extracellular fifteenth collagen region and a coding gene of a His tag are selected to be connected in series, and a gene sequence is optimized through pichia pastoris codon selection preference; and then the T-COL17R3 is constructed and expressed to obtain the T-COL17R3. Efficacy experiments prove that compared with similar products sold in the market, T-COL17R3 not only has excellent transdermal performance, but also has better cell proliferation and migration promoting capability, better capability of resisting early saccharification product ketoamine and later saccharification product dicarbonyl compounds, better capability of scavenging free radicals and resisting elastase, and can be used for preparing the anti-epidermal drug. In addition, synthesis of melanin in B16-F10 cells can be reduced, so that T-COL17R3 has excellent application potential in development of pharmaceutical compositions or skin care products with repairing, anti-wrinkle and firming or whitening and brightening effects.

The invention relates to application of a tea exosome in preparation of a medicine for improving skin pigmentation, the tea exosome is creatively extracted and purified, and the tea exosome can effectively inhibit proliferation of melanoma cells and inhibit expression of melanin generation related protein by scavenging free radicals and inhibiting tyrosinase activity, so that the effect of improving skin pigmentation is achieved. The intracellular melanin removal is promoted. In a mouse in-vivo experiment, after the tea exosome is applied, it is observed that the skin epidermis thickness of a mouse is reduced, the dermis thickness is increased, collagen arrangement is tighter and more ordered, the content is increased, and meanwhile generation of inflammatory factors is reduced. The tea exosome can significantly increase the content of a melanin autophagy key factor LC3B and reduce the content of P62 to promote melanin autophagy, and has good percutaneous infiltration capacity, thereby playing a role in improving skin pigmentation.

The invention belongs to the technical field of cosmetic efficacy evaluation, and discloses a sunscreen efficacy evaluation method and application thereof, and the method comprises the following steps: building a blank group; establishing a model group; establishing a sample group; performing constant-temperature incubation on the blank group, the model group and the sample group for a first period of time, recording a swimming track, and calculating swimming distance increment and after-sun burning pain relieving efficiency of each group of zebrafish; performing constant-temperature incubation on the blank group, the model group and the sample group for a second duration, recording the tail fin and dorsal fin area of the zebra fish, and calculating the sunburn prevention efficiency; performing constant-temperature incubation on the blank group, the model group and the sample group for a third period of time, recording the head melanin area of the zebra fish, and calculating the anti-sunburn efficiency; and grading the sunscreen effect of the sample. The method disclosed by the invention has the advantages of low cost, short test period, high reproducibility, high visualization degree, intuitive and understandable test result and the like, and can be used for accurately grading the sunscreen effects of chemical sunscreen agents, water-soluble sunscreen cosmetics and raw materials thereof from the whole animal level.

The invention discloses a high-transdermal recombinant humanized XVII type collagen as well as a preparation method and application thereof, and belongs to the technical field of synthetic biology. According to the preparation method, transdermal peptide TD-1, different functional fragments of human XVII type collagen and coding genes of His tags are selected to be connected in series, gene sequences are optimized through pichia pastoris codon selection preference firstly, and then the high-transdermal recombinant humanized XVII type collagen is obtained; and then the recombinant humanized XVII type collagen T-COL17-NC16 and the recombinant humanized XVII type collagen T-COL17 are constructed by expression of the recombinant humanized XVII type collagen T-COL17. Effect experiments prove that compared with similar products sold in the market, the skin-care product has more excellent transdermal performance, can improve cell proliferation and migration ability, also has obvious ability of resisting early saccharification product ketoamine and late saccharification product dicarbonyl compounds, better ability of scavenging free radicals and resisting elastase, and can be used for preparing the skin-care product. Moreover, synthesis of melanin in B16-F10 cells can be reduced, and the compound is expected to become a novel functional biological raw material to be applied to the fields of pharmaceutical compositions or skin care products and the like.

The invention relates to the technical field of whitening essence, and discloses whitening essence suitable for sensitive skin and a preparation method thereof.The whitening essence suitable for sensitive skin is prepared from, by mass, 2%-3% of prinsepia utilis royle oil, 1%-2% of portulaca oleracea extract, 1.5% of camellia yunnanensis flower extract, 0.5% of panax notoginseng root extract, 3% or less of nicotinamide, 1% or less of 1, 2-propylene glycol and the balance deionized water. 1%-1.5% of 1, 2-hexanediol, 0.1%-0.3% of sodium hyaluronate and 60%-70% of deionized water. According to the whitening essence suitable for the sensitive skin and the preparation method of the whitening essence, through the synergistic combination of prinsepia utilis royle oil (barrier repair), purslane (anti-inflammatory), camellia japonica (tyrosinase inhibition) and pseudo-ginseng (microcirculation improvement), melanogenesis is inhibited through multiple channels, the sensitive skin is relieved synchronously, nicotinamide (3%) is compounded with the prinsepia utilis royle oil, and the skin whitening effect is achieved. The synergism of whitening and barrier repair is enhanced through a dual mechanism of promoting ceramide synthesis and inhibiting melanin transport, and the problems that a traditional whitening agent has different degrees of irritation, allergy phenomena such as skin redness, swelling and pain are easily caused by improper use, and a skin intolerance phenomenon exists are solved.

The invention belongs to the technical field of cosmetics, and discloses a whitening composition, application thereof and cosmetics. The whitening composition is prepared from the following active ingredients in parts by mass: 16 to 24 parts of coix seed fermentation liquor, 8 to 12 parts of Chinese herbaceous peony extract combined factors, 22 to 38 parts of 4-butylresorcinol solution and 2 to 8 parts of zinc gluconate, through the synergistic effect of the four components, the activity of tyrosinase can be effectively inhibited, synthesis of cell melanin can be effectively inhibited, and the whitening effect is good.

The invention relates to the field of cosmetics, in particular to sea rice fermentation filtrate, a preparation method thereof and a whitening cosmetic. Inoculating the first fermentation seed solution and the second fermentation seed solution into a fermentation culture medium, fermenting at 25-30 DEG C to obtain a fermentation product, and removing thalli in the fermentation product; the fermentation culture medium is prepared from the following components in percentage by mass: 5 to 10 percent of sea rice powder, 1 to 5 percent of saccharides and the balance of water; the pH value of the fermentation culture medium is 4-5; the first fermentation seed solution is a saccharomyces cerevisiae strain fermentation seed solution; the second fermentation seed solution is a lactobacillus plantarum strain fermentation seed solution. The method can promote the growth of saccharomyces cerevisiae and lactobacillus plantarum while promoting the release of an active component phytic acid in the sea rice, and has a remarkable effect of removing excessive free radicals and inhibiting the activity of related enzymes for synthesizing melanin; therefore, the whitening effect of the cosmetic can be effectively improved.

The invention relates to the technical field of freeze-dried powder preparation, and discloses a white tomato exosome freeze-dried powder preparation method, which comprises: 1, manually picking white tomatoes 3-5 days after a color changing period, carrying out double-frequency ultrasonic cleaning, and pre-cooling in a 4 DEG C phosphate buffer solution containing 0.1% of vitamin C; according to the method, by virtue of an ultrasonic-cellulase synergistic crushing process, cells are mildly and efficiently crushed, so that the damage to an exosome structure is reduced, and the release efficiency and activity of the exosome are improved; the zebra fish embryo melanogenesis can be obviously inhibited, and the whitening and freckle-removing effects are relatively good.

The invention belongs to the technical field of microorganisms, and discloses a Lactobacillus paracasei B20 for inhibiting melanin from a plateau area and application of the Lactobacillus paracasei B20, the Lactobacillus paracasei B20 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.32434, and the preservation date is October 31, 2024. Metabolite of the lactobacillus paracasei B20 comprises phenylalanine, p-hydroxycinnamic acid and the like, has strong tyrosinase inhibition effect and anti-ultraviolet ability, and can significantly reduce generation of melanin in skin. In addition, the lactobacillus paracasei B20 also has relatively strong oxidation resistance, has good tolerance in artificial gastric juice and artificial intestinal juice, and can smoothly reach the intestinal tract of a human body. In addition, the lactobacillus paracasei B20 has a relatively obvious growth inhibition effect on skin conditioned pathogens such as staphylococcus aureus and enterococcus faecalis.

A group of polypeptides, which can be used as a tyrosinase inhibitor. The polypeptides have the effects of inhibiting tyrosinase activity, reducing melanin secretion, resisting oxidation, skin-whitening, spot-removing, etc. The polypeptides can be widely used in antioxidant drugs and in the preparation of skin-whitening cosmetics for resisting melanogenesis and lightening spots as a new raw material, and has good application scenarios.

The invention provides a preparation method of collagen and an application of the collagen in anti-aging. According to the invention, the anti-aging antioxidant collagen peptide F-5-B is obtained through enzymolysis and column separation identification. It is identified that the polypeptide has good DPPH free radical scavenging capacity, ABTS free radical scavenging capacity and lipid peroxidation reaction inhibiting capacity, the collagen peptide F-5-B can further inhibit melanoma cells from synthesizing melanin, and the polypeptide can further obviously increase the SOD level in the liver of a mouse. SOD can help the body resist attack of free radicals, so that the aging process is slowed down. Therefore, the anti-aging pharmaceutical composition prepared from the polypeptide has a relatively good application prospect.

The invention relates to an indole hair dye based on air oxidation. The hair dye provided by the invention is characterized in that a chemical strong oxidant is not added, and oxygen in air can be catalyzed by using an air oxidation catalyst and a metal ion catalyst to naturally finish the oxidative polymerization process of indole substances (natural bionic melanin precursor substances). The used reducing agent is a combination of cysteine and a derivative thereof and sodium sulfite and a derivative thereof, the oxidative polymerization speed of indole substances can be controlled, and finally generated melanin macromolecules are embedded in hair cortex, so that white hair is obviously blackened. The natural oxidation process does not need hydrogen peroxide, destructive strong base or organic base, so that the use of harmful chemical reagents is reduced, the formula is simplified, the hair dyeing process is milder, potential hazards to hair and scalp are reduced, and the natural oxidation hair dye is safe, environmentally friendly and sustainable.

The invention relates to a dihydroarteannuic acid compound as well as a preparation method and application thereof. The structure of the dihydroarteannuic acid compound is shown as a formula I in the specification. The dihydroarteannuic acid compound or the pharmaceutically or cosmetically acceptable salt of the dihydroarteannuic acid compound shows good melanogenesis inhibition activity and anti-inflammatory activity at the cellular level, has good safety, can be used as a melanogenesis inhibitor, and can be used for preparing anti-inflammatory drugs. The composition is used for preparing medicines for treating senile plaques, chloasma, freckles and hyperpigmentation after inflammation and cosmetics for whitening and removing freckles.

The invention discloses a preparation method of polydihydroxyindole and application of the polydihydroxyindole in hair dyeing, and belongs to the field of functional materials and the field of daily cosmetics. The polydihydroxyindole is obtained in the mode that Boc-true melanin is formed after true melanin is protected through phenolic hydroxyl groups, the Boc-true melanin is subjected to oxidative degradation, separation and purification and then deprotection, the true melanin is naturally extracted melanin or chemically synthesized melanin or melanin synthesized through a microbiological method, and the oxidative degradation method is an enzymatic oxidative degradation method. The obtained polydihydroxyindole is moderate in molecular weight and has excellent permeability on hair, a strong alkaline condition is not needed in the oligomer dyeing process, and hair quality damage can be reduced; the polydihydroxyindole is oxidized again in the hair dyeing process to generate melanin, and under the condition that the pH is 5-7, and in the presence of ferric ions, the polydihydroxyindole can be more tightly combined with keratin on the hair to coat the outer layer of the hair, so that the hair color is deepened, and the effects of dyeing and protecting the hair are achieved.

The invention discloses a polypeptide with a whitening effect and a preparation method and application thereof.The polypeptide is obtained from hydrolyzed protein of babylonia areolata, the amino acid sequence of the polypeptide is cysteine-arginine-proline-threonine-cysteine-serine-arginine-leucine-alanine-cysteine, and the amino acid sequence of the polypeptide is cysteine-arginine-proline-threonine-cysteine-serine-arginine-leucine-alanine. The compound can obviously inhibit the generation of melanin in cells and the activity of tyrosinase in vitro, has the characteristics of low toxicity, low irritation, good stability, safety and high efficiency, and can be applied to whitening cosmetics.

The invention discloses Janus microspheres co-loaded with melanin and tea polyphenol-magnesium as well as a preparation method and application of the Janus microspheres. The preparation method comprises the following steps: complexing tea polyphenol and magnesium ions under an alkaline condition to form nano-particles, and dissolving keratin in hair by using strong base to obtain melanin nano-particles; the two solutions are respectively mixed with methacryloyl collagen to prepare a solution as a mobile phase, vegetable oil is used as a dispersion phase solution, in a microfluidic device, a two-channel flow phase is coaxial and co-flow, the dispersion phase fluid disperses the mobile phase into monodisperse liquid drops by using a flow shear force, and the monodisperse liquid drops are subjected to ultrasonic dispersion. And curing the liquid drops under the irradiation of ultraviolet laser to form the Janus microspheres co-loaded with melanin / tea polyphenol-magnesium. By means of the microfluidic technology, high-uniformity preparation of the Janus microspheres co-loaded with melanin / tea polyphenol-magnesium is achieved, synergistic anti-oxidation and antibacterial treatment can be achieved, and the Janus microspheres can be applied to various biomedical applications with anti-oxidation and antibacterial requirements, such as promotion of healing of diabetic wounds, bacterial infectious wounds and the like.

The invention relates to the technical field of scalp care, in particular to a hair-blacking composition for promoting melanin secretion and a preparation method of the hair-blacking composition. Comprising the following components in parts by weight: water, ethanol, a ginseng root extract, a polygonum multiflorum extract, a cacumen biotae extract, a licorice root extract, an eclipta prostrata extract, a ganoderma atrum extract, a rhizoma bletillae root extract, a mulberry leaf extract, radix sophorae flavescentis powder, a glossy privet fruit extract, a raspberry fruit extract and a black sesame extract. According to the technical scheme, the ganoderma atrum extract is prepared through enzymolysis-ultrasonic combined modification, a cell wall structure is decomposed through compound enzyme, then cell remains are further broken through the ultrasonic cavitation effect, and the release rate of active peptide and polysaccharide is increased; the hair-blacking composition can promote the generation of hair melanin so as to blacken hair, improve the hair quality, enable the hair to become tough and elastic, and enable the hair to gradually become black, smooth and firm after being smeared on the scalp for a long time.

The invention discloses a five-membered heterocyclic compound as well as a preparation method, an intermediate, a composition and application thereof. Specifically provided is a compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound provided by the invention has excellent biological activity; on one hand, free radicals can be removed, so that activation of tyrosinase is reduced; on the other hand, the activity of activated tyrosinase can be inhibited, and generation of melanin is reduced from multiple aspects; besides, the compound can reduce skin pigmentation induced by ultraviolet (UVB), has no obvious stimulation and inflammatory cell infiltration during administration, is safe and good in tolerance, has better solubility and preparation performance, is good in skin feeling, and is expected to be widely applied in the industries of medicine, cosmetics and beauty. # imgabs0 #

The invention discloses a whitening active peptide with an effect of inhibiting melanin formation as well as a preparation method and application of the whitening active peptide. The amino acid sequence of the whitening active peptide is as follows: YYYDPWAGK. Whitening activity verification is carried out on the peptide, the relative tyrosinase activity in cells can be remarkably reduced to 164.26 + / -3.03% from 245.52 + / -1.55% by the peptide with the concentration of 200 mu g / mL, and meanwhile, the relative melanin content can be reduced to 130.05 + / -1.23% from 206.65 + / -4.33%. In addition, the peptide not only can significantly reduce the relative tyrosinase activity of zebrafish from 100 + / -0.36% to 60.42 + / -0.73%, but also can reduce the relative melanin content of zebrafish from 100 + / -2.01% to 63.74 + / -2.05%, and lays an important theoretical foundation for the research and application of zebrafish in the fields of functional food, health care products, cosmetics and medicines.

The application provides a tyrosinase-based transdermal delivery system for treating vitiligo, which is a core-shell structure, the core is tyrosinase, and the shell is a polymer shell layer. The application coats a polymer protective layer on the surface of the tyrosinase through in-situ polymerization reaction on the double bond of the tyrosinase, can effectively protect the activity of the tyrosinase and promote the transdermal delivery of the tyrosinase, and can control the targeted delivery of the tyrosinase nanogel to melanocytes in the deep part of the skin and hair follicle by adjusting the polymerization conditions of the polymer shell, so as to promote the in-situ synthesis of melanin. The transdermal delivery system of the application can also load active small molecules with anti-inflammatory function in the center of the tyrosinase, and the small molecules are released after being targeted and delivered to the inflammation area of vitiligo along with the tyrosinase nanogel, so as to relieve inflammation and protect melanocytes from damage.

The application discloses a whitening and freckle-removing composition, conditioner, medicine and cosmetic. The whitening and freckle-removing composition comprises broccoli, ganoderma lucidum and inula japonica in the composition; the broccoli comprises broccoli raw materials and / or broccoli extract, the ganoderma lucidum comprises ganoderma lucidum raw materials and / or ganoderma lucidum extract, and the inula japonica comprises inula japonica raw materials and / or inula japonica extract. The application has significant synergistic activity by scientific compounding of the broccoli and the inula japonica, has significant inhibitory effect on tyrosinase activity, can inhibit the expression and function of the rate-limiting enzyme TYR in the melanin synthesis process, has significant whitening and freckle-removing activity, is safe and efficient, and can be applied to various conditioners, medicines and cosmetics.

The invention relates to an arteannuic acid compound as well as a preparation method and application thereof. The structure of the arteannuic acid compound is shown as a formula I in the specification. The arteannuic acid compound or the pharmaceutically or cosmetically acceptable salt thereof provided by the invention shows good melanogenesis inhibition activity and anti-inflammatory activity at a cellular level, has good safety, can be used as an inhibitor for melanogenesis, and can be used for preparing anti-inflammatory drugs. The composition is used for preparing medicines for treating senile plaques, chloasma, freckles and hyperpigmentation after inflammation and cosmetics for whitening and removing freckles.

The invention relates to a hair dye based on monatomic nano-enzyme, the hair dye is composed of a first solution and a second solution which are independently subpackaged, the first solution is a solution containing melanin small molecule precursor substance 5, 6-dihydroxyindole and monatomic nano-enzyme, and the second solution is a solution containing hydrogen peroxide; the monatomic nano enzyme is nitrogen-doped hollow carbon microspheres loaded by metal iron, copper, manganese or silver atoms. During hair dyeing, the melanin small-molecule precursor substance 5, 6-dihydroxyindole enters hair through hair cuticles and then is quickly oxidized and polymerized into melanin under the action of monatomic nano-enzyme and hydrogen peroxide, so that safe, quick and permanent hair dyeing is realized. According to the hair dye, the harm of hydrogen peroxide to a human body is remarkably reduced while the hair dyeing time is effectively shortened, and the hair dye has good dyeing capacity and excellent washing fastness and biological safety.

The invention belongs to the field of shampoo, and discloses hair-blacking and alopecia-stopping Chinese herbal medicine shampoo and a preparation process thereof. The shampoo cream is prepared from the following raw materials in parts by weight: 10 parts of cacumen biotae, 10 parts of Chinese honey locust, 110 parts of soapberry, 6 parts of szechwan chinaberry fruit, 5 parts of lucid ganoderma, 5 parts of pine needle, 5 parts of eclipta, 5 parts of garden balsam stem, 5 parts of tea seed powder, 5 parts of rhizoma drynariae, 5 parts of glossy privet fruit, 5 parts of mulberry leaf, 4 parts of duckweed, 3 parts of polygonum multiflorum, 3 parts of angelica sinensis, 3 parts of tribulus terrestris and 2 parts of ginseng. The hair-loss-preventing and hair-growing shampoo has the comprehensive effects of preventing hair loss and growing hair, namely activating hair follicle activity, promoting hair cell proliferation and improving scalp microcirculation through the components such as the radix polygoni multiflori preparata and the cacumen biotae. The hair blackening and brightening agent contains eclipta, mulberry leaves and the like, can promote melanin synthesis, inhibit decomposition, repair damaged hair and enhance hair gloss. The effects of controlling oil, removing dandruff, relieving itching, resisting inflammation, nourishing and conditioning are achieved.

The invention relates to an anti-ultraviolet-damage composition and application thereof in sunscreen products, and the anti-ultraviolet-damage composition is prepared from the following raw materials in parts by weight: 5-8 parts of oxhide tea leaf extract, 3-7 parts of green alga extract, 1-4 parts of dogwood extract, 8-10 parts of sea-buckthorn extract, 2.5-4 parts of butyrospermum parkii butter and 5-8 parts of camellia oleosa seed oil. All the raw materials have a synergistic effect, and free radicals generated by ultraviolet induction are neutralized, so that oxidative stress is relieved, and skin cells are protected from being damaged; ultraviolet rays are absorbed and are prevented from penetrating through the skin, so that direct damage of the ultraviolet rays to the skin is reduced; the activity of tyrosinase is regulated or a melanin synthesis pathway is blocked, the accumulation of melanin is reduced, and the effects of preventing and improving stains, darkness and the like are achieved.