The invention relates to a preparation method of a
coreopsis tinctoria and
lithospermum erythrorhizon
traditional Chinese medicine lipstick with anti-inflammatory and repairing effects. Aiming at the problems that active ingredients of the traditional Chinese herbal
medicine lipstick are easy to degrade, easy to break at low temperature, insufficient in anti-inflammatory repairing effect and the like, a freezing crushing-supercritical extraction-
microsphere self-
assembly process is initiated and comprises the following steps: 1, quick-freezing
coreopsis tinctoria,
lithospermum erythrorhizon and roselle in
liquid nitrogen, performing high-pressure micro-jet crushing, and combining cetyltrimethylammonium
bromide / supercritical CO2 extraction, so that the yield of
alkannin is increased; 2, injecting the extract into an
olive oil carrier containing camel fat
wax, and self-assembling to form core-shell microspheres to realize lip temperature triggered self-repairing; and 3,
cynomorium songaricum polysaccharide is added to react with salivary
enzyme to generate a biological
adhesive film, and the TNF-alpha inhibition rate is increased by cooperating with the honey-fried
licorice root extract, the sea buckthorn seed oil and the like. The
lipstick is suitable for lip protection in extreme environments such as high cold,
sand storm and
plateau strong
ultraviolet rays, and fills the technical blank of Chinese herbal
medicine lipsticks in the field of molecular-level slow release and intelligent response repair.