The invention relates to a preparation method of a licorice root active extract based on microjet synergistic subcritical
water extraction, which comprises the following steps: S1,
raw material pretreatment: crushing dried
licorice roots to obtain licorice root
powder; s2,
slurry preparation: mixing the licorice root
powder with deionized water, and stirring and dispersing to prepare uniform suspension
slurry; s3, microjet
cell disruption: feeding the
slurry prepared in S2 into a microjet device, accelerating liquid in the slurry to
supersonic speed to form high-speed jet, disrupting
cell walls of licorice root cells, and fully exposing
intracellular active components in a water phase; s4, carrying out subcritical
water extraction, transferring the slurry into a reaction kettle, sealing, introducing
inert gas to replace internal air, and carrying out dynamic stirring extraction; and S5, carrying out
solid-liquid separation, cooling treatment, pressure relief and
solid-liquid separation, and collecting a clarified extracting solution to obtain the
licorice root extract. By adopting the technical scheme, the invention provides the preparation method and the application of the licorice root active extract based on microjet synergistic subcritical
water extraction, the
plant cell structure can be thoroughly destroyed, the efficient, rapid and green extraction can be realized under the mild condition, and the high-activity and high-content licorice extract can be obtained.